#=GF ID PrnB
#=GF AC PF08933.15
#=GF DE Monodechloroaminopyrrolnitrin synthase PrnB
#=GF PI DUF1864;
#=GF AU Mistry J;0000-0003-2479-5322
#=GF AU Sammut SJ;0000-0003-4472-904X
#=GF SE pdb_1zee
#=GF GA 27.00 27.00;
#=GF TC 27.00 27.10;
#=GF NC 26.80 24.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Family
#=GF CL CL0380
#=GF RN [1]
#=GF RM 17924666
#=GF RT The second enzyme in pyrrolnitrin biosynthetic pathway is
#=GF RT related to the heme-dependent dioxygenase superfamily.
#=GF RA De Laurentis W, Khim L, Anderson JL, Adam A, Johnson KA,
#=GF RA Phillips RS, Chapman SK, van Pee KH, Naismith JH;
#=GF RL Biochemistry. 2007;46:12393-12404.
#=GF RN [2]
#=GF RM 20421301
#=GF RT The ternary complex of PrnB (the second enzyme in the
#=GF RT pyrrolnitrin biosynthesis pathway), tryptophan, and cyanide
#=GF RT yields new mechanistic insights into the indolamine dioxygenase
#=GF RT superfamily.
#=GF RA Zhu X, van Pee KH, Naismith JH;
#=GF RL J Biol Chem. 2010;285:21126-21133.
#=GF DR INTERPRO; IPR015029;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This protein family includes Monodechloroaminopyrrolnitrin
#=GF CC synthase PrnB from Pseudomonas fluorescens and similar bacterial
#=GF CC proteins. PrnB is involved in the biosynthesis of the antifungal
#=GF CC compound pyrrolnitrin. It is organised into two domains: a small
#=GF CC N-terminal capping domain that consists of 7 alpha-helices and
#=GF CC the core helical domain, which is related to myoglobin. PrnB
#=GF CC shows structural homology to the heme b-dependent two-domain
#=GF CC indoleamine 2,3-dioxygenase enzyme (IDO, Pfam:PF01231) and to
#=GF CC the tryptophan 2,3-dioxygenase (TDO, Pfam:PF03301) family [1,2].
#=GF SQ 128
#=GS A0A250ITK4_9DELT/10-361 AC A0A250ITK4.1
#=GS V6JUA0_STRNV/2-390 AC V6JUA0.1
#=GS A0A4V2ZFB4_9ALTE/3-391 AC A0A4V2ZFB4.1
#=GS A0A7X0JWE1_9GAMM/2-389 AC A0A7X0JWE1.1
#=GS A0A8J8KRZ5_9ACTN/43-357 AC A0A8J8KRZ5.1
#=GS K6XH21_9ALTE/5-391 AC K6XH21.1
#=GS A0A0M3T2C7_9GAMM/2-387 AC A0A0M3T2C7.1
#=GS F2R416_STRVP/11-361 AC F2R416.1
#=GS A0A839UWF8_9GAMM/2-388 AC A0A839UWF8.1
#=GS A0A098L8S6_9BACT/18-366 AC A0A098L8S6.1
#=GS E8U445_DEIML/24-365 AC E8U445.1
#=GS A0A5R9M054_9ACTN/28-366 AC A0A5R9M054.1
#=GS A0A841G2N7_9ACTN/4-374 AC A0A841G2N7.1
#=GS Q4KAM6_PSEF5/14-360 AC Q4KAM6.1
#=GS A0A095X0D8_9GAMM/2-388 AC A0A095X0D8.1
#=GS Q3IDE5_PSET1/2-388 AC Q3IDE5.1
#=GS A0A0F7FU76_9ACTN/30-366 AC A0A0F7FU76.1
#=GS A0A7L4Y877_9ACTN/24-373 AC A0A7L4Y877.1
#=GS A0A542QNV9_9ACTN/22-371 AC A0A542QNV9.1
#=GS A0A8J3ZXS5_9ACTN/1-378 AC A0A8J3ZXS5.1
#=GS A0A0Q0H8X1_9GAMM/5-391 AC A0A0Q0H8X1.1
#=GS A0A3A4BCG6_9ACTN/18-394 AC A0A3A4BCG6.1
#=GS A0A2N3Y4Z1_SACSN/14-351 AC A0A2N3Y4Z1.1
#=GS A0A7K1Y8W7_9SPHI/2-386 AC A0A7K1Y8W7.1
#=GS A0A4R7V2M0_9PSEU/1-149 AC A0A4R7V2M0.1
#=GS A0A166XFK5_9GAMM/2-388 AC A0A166XFK5.1
#=GS A0A1M5Q393_STRHI/40-368 AC A0A1M5Q393.1
#=GS A0A4P6U8C4_9NOCA/16-362 AC A0A4P6U8C4.1
#=GS A0A2W2KKV8_9ACTN/44-276 AC A0A2W2KKV8.1
#=GS E1SN32_FERBD/2-389 AC E1SN32.1
#=GS A0A4V2ELC1_9PSEU/91-343 AC A0A4V2ELC1.1
#=GS A0A1C5GAZ2_MICEH/1-346 AC A0A1C5GAZ2.1
#=GS A0A4U1B922_9GAMM/5-391 AC A0A4U1B922.1
#=GS F2JUA2_MARM1/3-386 AC F2JUA2.1
#=GS V6KCF9_STRNV/25-370 AC V6KCF9.1
#=GS A0A4V2ELC1_9PSEU/2-93 AC A0A4V2ELC1.1
#=GS A0A4V5NWG0_9GAMM/2-389 AC A0A4V5NWG0.1
#=GS E3BJD8_9VIBR/2-389 AC E3BJD8.1
#=GS A0A8J3ZGI1_9ACTN/9-381 AC A0A8J3ZGI1.1
#=GS A0A0F4PQL1_9GAMM/2-389 AC A0A0F4PQL1.1
#=GS A0A4Q0YII9_9GAMM/2-389 AC A0A4Q0YII9.1
#=GS A0A7K3GM81_9ACTN/51-350 AC A0A7K3GM81.1
#=GS K0F9H5_NOCBR/20-344 AC K0F9H5.1
#=GS A0A2K5R2R7_CEBIM/160-387 AC A0A2K5R2R7.1
#=GS A0A6H1UFU1_9GAMM/2-389 AC A0A6H1UFU1.1
#=GS A0A1H2S9V3_9PSEU/2-383 AC A0A1H2S9V3.1
#=GS A0A365H9F2_9ACTN/31-412 AC A0A365H9F2.1
#=GS A0A1G8XRS6_9BACT/26-369 AC A0A1G8XRS6.1
#=GS A0A1I0HZ79_THASX/2-388 AC A0A1I0HZ79.1
#=GS A0A4U1L7V8_9SPHN/5-392 AC A0A4U1L7V8.1
#=GS A0A6G9H4K2_9ACTN/16-363 AC A0A6G9H4K2.1
#=GS A0A1H8Y654_9PSEU/1-377 AC A0A1H8Y654.1
#=GS A4ABU7_9GAMM/2-390 AC A4ABU7.1
#=GS A0A0S2K0S0_9GAMM/2-388 AC A0A0S2K0S0.1
#=GS A0A540WC81_9ACTN/29-348 AC A0A540WC81.1
#=GS A0A7W6G595_9SPHN/2-388 AC A0A7W6G595.1
#=GS Q8E972_SHEON/5-391 AC Q8E972.1
#=GS A0A1G9Y6N9_ALLAB/42-362 AC A0A1G9Y6N9.1
#=GS A0A100Y3K5_9ACTN/37-372 AC A0A100Y3K5.1
#=GS A3QIX5_SHELP/2-388 AC A3QIX5.1
#=GS A0A3M0AI50_9GAMM/2-386 AC A0A3M0AI50.1
#=GS A0A810KXC3_9ACTN/10-370 AC A0A810KXC3.1
#=GS A0A089X1U0_STRGA/22-358 AC A0A089X1U0.1
#=GS A0A8J3INP1_9CHLR/21-334 AC A0A8J3INP1.1
#=GS A0A2A2Z0G9_9ACTN/7-336 AC A0A2A2Z0G9.1
#=GS A0A364Y1V6_9BACT/20-372 AC A0A364Y1V6.1
#=GS B8KV85_9GAMM/6-393 AC B8KV85.1
#=GS A0A2N1DCJ9_9ALTE/5-391 AC A0A2N1DCJ9.1
#=GS A0A6G9H1S2_9ACTN/12-357 AC A0A6G9H1S2.1
#=GS K7AL66_9ALTE/5-391 AC K7AL66.1
#=GS A0A2Z6UBV8_GLASK/2-389 AC A0A2Z6UBV8.1
#=GS A0A0Q0KGE5_9GAMM/2-388 AC A0A0Q0KGE5.1
#=GS A0A1M5E317_9ALTE/3-386 AC A0A1M5E317.1
#=GS A0A2T0GWJ9_ACTMO/14-362 AC A0A2T0GWJ9.1
#=GS A0A261GI73_9GAMM/42-355 AC A0A261GI73.1
#=GS A0A1M5XZR4_9GAMM/2-388 AC A0A1M5XZR4.1
#=GS A0A2S6GC38_9PSEU/5-372 AC A0A2S6GC38.1
#=GS A0A1Q5LXD5_9ACTN/24-369 AC A0A1Q5LXD5.1
#=GS A0A7W7C6V9_9PSEU/2-376 AC A0A7W7C6V9.1
#=GS A0A7K2L0H5_9ACTN/23-358 AC A0A7K2L0H5.1
#=GS A0A7J7ZHX8_PIPKU/192-403 AC A0A7J7ZHX8.1
#=GS A0A6C7E6K0_ILUCY/11-397 AC A0A6C7E6K0.1
#=GS A0A7W0HVV1_9ACTN/95-412 AC A0A7W0HVV1.1
#=GS A0A8A8DIL7_9BURK/1-344 AC A0A8A8DIL7.1
#=GS A0A1V9G2Q7_9BACT/43-323 AC A0A1V9G2Q7.1
#=GS A0A495XFN4_9PSEU/2-349 AC A0A495XFN4.1
#=GS A0A5C9A7C7_9GAMM/2-388 AC A0A5C9A7C7.1
#=GS A0A2R4T8D7_9ACTN/34-375 AC A0A2R4T8D7.1
#=GS L5LS41_MYODS/187-399 AC L5LS41.1
#=GS A0A1E5PIT5_9ACTN/13-362 AC A0A1E5PIT5.1
#=GS A1SB64_SHEAM/5-391 AC A1SB64.1
#=GS A0A0F4NW72_PSEO7/3-388 AC A0A0F4NW72.1
#=GS A0A1G8W512_9GAMM/2-389 AC A0A1G8W512.1
#=GS J0U836_9BURK/3-389 AC J0U836.1
#=GS A0A6N0X3I6_9SPHN/1-388 AC A0A6N0X3I6.1
#=GS A0A1I1M8M0_9BACT/29-382 AC A0A1I1M8M0.1
#=GS S9PK82_9DELT/1-237 AC S9PK82.1
#=GS Q1YT13_9GAMM/2-390 AC Q1YT13.1
#=GS A0A652KBU9_9ACTN/23-368 AC A0A652KBU9.1
#=GS A8H9J6_SHEPA/2-388 AC A8H9J6.1
#=GS A0A0F4QE14_9GAMM/2-389 AC A0A0F4QE14.1
#=GS A0A2N5Y1J1_9GAMM/3-390 AC A0A2N5Y1J1.1
#=GS A0A2C9ZZH4_PSEDV/2-388 AC A0A2C9ZZH4.1
#=GS A0A2P8B2B2_9ACTN/31-373 AC A0A2P8B2B2.1
#=GS A0A395JV47_9GAMM/3-390 AC A0A395JV47.1
#=GS A0A1C6QHX0_9BURK/1-305 AC A0A1C6QHX0.1
#=GS A0A7J7Z3K7_MYOMY/40-255 AC A0A7J7Z3K7.1
#=GS A0A7W7QBW1_9PSEU/1-353 AC A0A7W7QBW1.1
#=GS A0A1S2KG16_9ACTN/46-375 AC A0A1S2KG16.1
#=GS A0A0K1JDM7_9MICO/66-364 AC A0A0K1JDM7.1
#=GS A0A1H3MGE0_9BACL/52-345 AC A0A1H3MGE0.1
#=GS A0A2K8KNV6_9GAMM/18-404 AC A0A2K8KNV6.1
#=GS B8KTW6_9GAMM/2-388 AC B8KTW6.1
#=GS A0A4R2KN42_9GAMM/3-390 AC A0A4R2KN42.1
#=GS A0A561UPP3_9ACTN/14-356 AC A0A561UPP3.1
#=GS A0A1C3EKP0_9GAMM/2-389 AC A0A1C3EKP0.1
#=GS A0A4Q7X553_9ACTN/36-272 AC A0A4Q7X553.1
#=GS A0A8J4DU23_9ACTN/24-352 AC A0A8J4DU23.1
#=GS A0A2V4N0T0_9ACTN/16-352 AC A0A2V4N0T0.1
#=GS A0A7J7Z3J0_MYOMY/193-404 AC A0A7J7Z3J0.1
#=GS A0A2S7K8P1_9PROT/2-389 AC A0A2S7K8P1.1
#=GS A0A1S2PD07_9ACTN/38-272 AC A0A1S2PD07.1
#=GS G7Z6M6_AZOL4/72-388 AC G7Z6M6.1
#=GS Q12IK0_SHEDO/5-391 AC Q12IK0.1
#=GS G4QG60_GLANF/7-397 AC G4QG60.1
#=GS A0A371REP4_9PROT/14-400 AC A0A371REP4.1
#=GS A0A563F2Q4_9PSEU/14-323 AC A0A563F2Q4.1
#=GS A0A3R9UH24_9ACTN/11-361 AC A0A3R9UH24.1
A0A250ITK4_9DELT/10-361 .................................................mh--AAITALDPLDAL--ATMRRLPEL---.-NQQ.KDV.P...G..I..LRLLHGILPPPGKA--------...--RT...WSYV.EAAAAMRDIGFFLGSLKRH..G-HEP..VE--IVPALEP.I..LLEL--ARVTDLPPRETLLHVTVWNPPSPDAERRYTCCQAEVHLLESVRISMVSLESALHRLV..EL..YE.LPIGSRLFAPMCDDVAEK...LKKMVESIVYAYR.....TIPPRVFV.Q.ELRPY...............YDPIQVG.GQSYLGPGAVEMP-LFLLDHILWGS.R...S.....E...H..AE...YKSFKETYLPYVLPQLRTLHGRFLGHISLLERVLEEV.E.A..M.GT.....--..LEEPVRG--------.GL.KSLDKIFEVLLRFRAPHVGLAEQAYQVEse..thSVGSGGYAPSMLGDLLAL.T.-.-.RDARS.RL----------------tavlrgaevse......................................................................
V6JUA0_STRNV/2-390 ..................................................t-TAADDFDRWIRNDFVALNTLLEEAHFA.AEGR.IPHdR...P..E..LATARRRIGHEGAELVGRITDG...GAPHalpTKDD.ERYELLGSVGLYLGACRRH..EIEGP..QS-AAWPL---.-..--AQLLASSLGVVPRFVFAHQALYNRAVGDTFRTFTSLADERAFILYNGLSVLAYQRTAAALR..RV..PA.LGVSSPLTAYPLREARSG...LEDVLDLGRTLGK.....TLDVDRFF.L.NIRPY...............FKAHRVG.GVEYRGVNAGDFAAINTIDVLLGLC.S...P.....Y...D..PF...YQALLTEKYPYMPPEDQATLRATVTAEPLLDAFVRET.AaG..P.LT.....PQ..LRDNAELFLAVCRLH.GA.ASAFHHHRLVVPFLQAPAARAPQERESGt...adLTTSGPPLHVVMGTLARL.V.D.L.RTARQ.RP----------------gtdggarpaldrlrqal................................................................
A0A4V2ZFB4_9ALTE/3-391 ...................................................TKNVERMDDWIRKDFKQINTALEELYFA.QEDP.SQV.G...G..V..GNAYKEQLLNEGNCRVSALLRE...GNTD...EGFD.NGFDLLGNVGLFMAACRRH..ELTNP..ANEKRSPLVDA.S..ALAMQLGASLGVTPRFASAHLETHNMAKNGFYKTFTNLPDEQRFIDYNTRGVFAFIRASEALL..HA..LP.LGISHPITYDLLMVAKQA...LEDVVENNQQLFD.....ELDVARFF.H.SVRPY...............YKPYRVG.LHEYRGANAGDFAGINVIDLLLGLC.R...A.....D...D..PY...YSQLLVDKFLFMRPDDQLTLRDCMRRKSLMDCFLKSL.S.KgeE.QS.....GW..YQKNLAVFVQVCEAH.GQ.TAIQHHELLIRRFIEAPAATSNATEKED......LTASGPPLPVLLKGLKKL.C.D.L.RSAAD.VEGIPTRFGDLTRLRESL.................................................................................
A0A7X0JWE1_9GAMM/2-389 ...................................................TANVENFDRWIRSSFIEINTELEKLYQQ.QDDK.ANV.V...G..I..GDSLKRQLEEEGRSLIAELLRE...GNTD...EGFD.AGFDLLGNVGFYMAACRRH..EITEP..SREDTSPLKEA.S..ALALQLGASLGVTPRFATAHLTTHNRAINGVAKSFTSLEDEFIFNEYNTRAVLAYKRAADALF..RT..VP.LGMSNVSVPDLLDAAYDA...LEDVIRLNDILFE.....KLDVNAFF.Y.LVRPY...............YKPYRVG.REIYRGANAGDFAGINIIDLMLGLC.R...A.....D...D..SY...YSQLLVDKMLYMMPEDQRCLMDCMRRPSLMDQLLQSP.D.S..E.QD....sEW..FQLVASKFLKVCDAH.GR.TAAQHHNNLVEKFITKPSQGMDEVYANK......LTASGPPLPVLLRSLAKL.R.D.L.RLAAE.RDDIPSRYRDIETIRNSL.................................................................................
A0A8J8KRZ5_9ACTN/43-357 ............................sslvrvfarslpsaqavagfspa----------------------------.----.---.-...-..-..----------------------...----...----.ECLAAMRDLGMYIGSLKRH..G-LSP..FE--IVPRAAG.A..CESL--GRRTGMIPRDTVYHYTCWNPV-GERERLYTGHPMERCLVDAVRTCIPDLARAVDLGH..AL..RG.DDPCGPAYAGRVLALASY...VSSADRAMGDVAA.....QVAPEFFA.L.VLRPY...............FEDVHIS.GRRYMGPAAAHVP-LFLIDTLLWSS.D...R.....C...A..PQ...YGQFCDEAAAHTLPHWRQWFSEWSRVPSVTSRVARAL.G.G..S.CA.....PA..DMEHIYA--------.SA.QGLRQALRSLTRFRGKHLVMARRAYHEEvr..lyDLGSGGGSVGLLAEILTL.T.-.-.RQN--.------------------atmvga...........................................................................
K6XH21_9ALTE/5-391 ..................................................t-PKTQAFDSWIRSDFVQLNDELETLYFE.QEDK.SNV.A...G..I..GDDIKQQLEREGRDLIKELLAE...GNTD...QGFD.SAFDLLGNVGLYMAACRRH..EITEP..SRETQSPLVEA.S..ALAMHIGASIGVTPRFATAHLTTHNSAQNGIYKRFTSLKDEKLFLDFNTRGILAYKRAADALL..KI..QP.LGISHPISHDLLVTCQKA...LQEVIDSNAILFE.....RLDATRFF.Y.CVRPY...............YKPYRVG.SQVFRGANAGDFAGINVIDMQLGLC.M...A.....N...D..PN...YSQLLVDKFLYMMPEDQTLLRDCMRRESIMNDFLIAK.D.C..S.DQ.....DW..YQANLKQFLIACELH.GE.TANQHHEQLVNKYITQPSTDLSQAHLKT......VTASGPPLAALLSGLEKL.K.D.K.RMANE.RSDILTRFEDLNSLKASL.................................................................................
A0A0M3T2C7_9GAMM/2-387 .................................................tp--NSLTFDHWIRNRFVELNTELELLYKN.QNER.INV.N...Q..V..GDQIKKTLEDEGRDLIKQLLSE...GNTD...EGFD.NAFDLLGNVGLYMAACRRH..EITDP..SKDSSSPLKEA.S..GLAMNIGASIGVVPRFATAHLSTHNKAVDGVYKSFTSLPAEKLFLDYNTKAILAYKRAADALL..KL..HS.LGISHPMCQELLQVVKVS...LIDVIQSNQFLFD.....QLSVDDFF.F.SVRPY...............YKPYHVG.FQVYRGANAGDFAGINVIDILLGLC.L...A.....K...E..PA...YSQMLVDKFMYMMPEDQGILRDCMRRTSFMDDFLNAT.D.S..N.AK.....-W..YQDNLTLFLEICELH.GK.AATQHHNQLVEKYIATPSNSLKETQLDN......ITASGPPLEVLISALEKL.R.D.R.RAAAD.RNDIPTRFKDIETLKNR-l................................................................................
F2R416_STRVP/11-361 .........diraadplgadallnavpamnadgdvaaltvalramvpdldr----------------------------.----.---.-...-..-..-------------A--------...--AQ...WSVG.HALAAMRDLGILLGSLKRH..G-VQP..AE--AVPEVLP.-..ALEL-LGLRTDMVPRDTVHHYTTWNPV-GPRRRSYTGHPTEFLLQDAVRMVLPGLVAALDDCG..RI..AR.LEPYDPGFAAALDRVARH...LRAMVESIDLTVA.....RVPPEYFA.L.TLRPY...............FEEVEIA.GRDYLGPAAAQVP-LWPVDLTLWQC.D...R.....S...D..PA...YDAFLADSVPYALPSWRAFHARHRGGVSAVSKLSAAV.S.W..E.GA.....DR..LPASLTA--------.SA.EALSRVLRVLKTFRARHLGIARKAYHEDvr..lyEEGSGGAPVALLRSVLDL.TrE.N.ETMVR.RATVRRR-----------paga.............................................................................
A0A839UWF8_9GAMM/2-388 ..................................................s-SNSQAFDEWIRHRFVALNSELEQRYAQ.QADR.ANV.V...G..V..GDDLKQQLESEGRALISALLAE...GNTD...QGFD.KAFDLLGSVGLYMAACRRH..EITEP..SRETTSPLVEA.S..ALAMHIGASIGVTPRFATAHLTTHNRAVNGVYKRFTDLPDEKIFVDYNTRGILAYKRAADALL..KI..LP.LGIAHPITQDLLQVAERA...LQDVIDANDQLFD.....KLDTDQFF.Y.CVRPY...............YKPHRVG.QQVYRGANAGDFAGINVIDMLLGLC.F...A.....N...E..PS...YSQILVDKFLYMMPEDQLILRDSMRRTSLMDSFLEHQ.A.D..R.DQ.....DW..YQTNLRHFLAVCERH.GD.TAIQHHDQLVSKYIEKPSAHIEQQHIEK......ITASGPPLHVLLGALEKL.R.D.R.RAAAP.RTDIRTRHDDIAHLKSL-l................................................................................
A0A098L8S6_9BACT/18-366 ...........................kkisqeidkldpiqidrlipfihk----------------------------.LNRE.KNV.Q...A..L..AEILYKHLPYPERL--------...--ER...FTYN.ESIACMRDIGIFLGSLKKH..G-TEP..VE--VIPELDY.V..-LDV-LSDKTNLPPRDTLFHYTIWNPSGLR-VRTYTGLSDEIHLIESVKMSMFPLVDAIYNLI..EL..HQ.TPLNSPAFEEICNIAEEN...LSGMINGIVYAKR.....NVSPAVFA.N.ELRFY...............FDPISLY.RREFIGPGAVEMP-LFVFDHLLWSS.E...T.....N...D..EE...YVKFKITYLPFNQPDIRDIYYNYDNQPSLATKVIEAL.K.K..N.PG.....-Y..CQQTAKS--------.-A.RALLSLCNRLKSFRMPHKKLAEESYAQQk...erSHGSGGYSTDILSHIISL.N.-.L.KTIAD.IEQA--------------itryg............................................................................
E8U445_DEIML/24-365 .........ldpfglddaladlpalnaradvpaltallqhmtaqykhltll----------------------------.----.---.-...-..-..----------------------...----...-DAE.STHATMRDFGIVLGSLKRH..G-VEP..LS--VVPHLEP.I..LLDL--GGQHDMVPRDTVLHYTVWNPD-GERRRLYTGDPQERELQDAVTNVFPHLSASLALSD..SL..AD.LDPRDVRFAPLAMHLART...SEVMVDTIDRVTQ.....HVSPIFFA.Q.TMRPY...............FEEIHVN.GRAYLGPAAAQVP-LWLIDITLWAS.D...R.....S...H..PA...YEHFLQESLQYSPPSWRAFYAAHSARPSLVTKVSALL.A.S..D.AH.....--..--QHDRNLLR--SAD.AL.TAL---LRTLKVFRGRHLGIARRAYAEDvr..lyEHGSGGAPIELLKTITQL.T.K.E.NEAAV.RAR---------------vggrp............................................................................
A0A5R9M054_9ACTN/28-366 ....................................dplgadeaceklrvm----------------------------.-NAD.GDV.S...G..M..VTALRELLPATDVL--------...--DD...FSTV.ENLAAMRDLGIFLGSVKRH..G-TEP..LD--AVPEALP.V..LRAL--GRRTGMVPRDTVHHYTAWNPVG-ARQRMYTGDPMEACLQDAVRMVFPSLCASLDACS..EL..AT.LEPHDSRFSSCLDRLAGL...VQAMVDSIDFTIA.....NVSPVFFA.R.VLRPY...............FEEITLD.GREYLGPAAAQVP-LWLVDLTLWQS.D...R.....S...T..GR...YESFLTESVPYSLPAWRTFHARYQGSPSAVGKLSFAI.S.W..E.EA.....DR..LPPTLRA--------.SA.VALARVLRILKTFRARHIRIAREAYSDEvr..lyDYGSGGAPVELLRSVLDL.T.R.-.-----.------------------enetlvrrste......................................................................
A0A841G2N7_9ACTN/4-374 ................................................tpl----AAYDAWLRSRFTDLNTGLEEAYFA.ARDD.Q-I.A...-..G..HDAAKDAILREGAALIARIG--...-DIP...HDDG.DRYKLLGAVGFHLAACARH..GVGDA..TL-----LAPA.W..ALARLLGSALDVAPRFVFSHQSLYNPAVGDRFHMFTTLPDEALFITRNGEAVLAYRRAAHALS..AV..AA.MGVSNPMAAYLFEDAAAA...LGDVLRFSQSLAR.....ELDPERFY.L.NIRPY...............FTPHVVG.RTEFRGVNAGDFAAINVVDLLLGLC.S...P.....S...D..PF...YQEVLAEKRPYLPPGDGAEIQAVLTVPSLLDRFAAEA.A.V..E.VT.....PG..LRRNAELFLAVCRAH.GA.AYAFHHHRLVADFIEKPAADRPT---PV......GSSSGPPMEVVLGILGRL.A.D.L.RAARD.RP----------------gtargrleglraal...................................................................
Q4KAM6_PSEF5/14-360 ...................................................THAAVAACDPLQAR--ALVLQLPAL---.-NRD.KDV.P...G..I..VGLLRDFLPVSGVP--------...--SS...WGFV.EAAAAMRDIGFFLGSLKRH..G-HEP..VD--LVPGLER.V..LLDL--ARVTDLPPRETLLHVTVWNPAAADAQRSYTGLPDEAHLLESVRISMAALEAAIALTV..EL..SD.VSLRSPAFAQGCDELEAY...LQKMVESIVYAYR.....FISPQVFY.D.ELRPF...............YEPIRVG.GQSYLGPGAVEMP-LFVLEHVLWGS.Q...S.....D...D..PA...YREFKETYLPYVLPAYRAVYARFATKPALIDRALDEA.R.A..V.GT.....--..QGEHVRA--------.GL.TALERVFKVLLRFRAPHLKLAERAYEAGrs..gpTTGSGGYAPSMLGDLLTL.T.-.-.-CAARsR--IRA------------alde.............................................................................
A0A095X0D8_9GAMM/2-388 ..................................................s-TNVEHFDHWVRSTFAELNTQLEEHYFA.QDDR.ARV.A...G..V..GEDLKARLKAEGNEHIARLLAE...GNTD...EGFD.AGFDLLGNVGLFMAACARH..GAADQ..H-AKDGGLPEA.S..ALALQLGASLGVTPRFATSHLTTHNRAVEGRYKSFTTLRDEYLFTDYNTRGILSYKRAGDALL..RV..LP.LGVSHPVAADLLRAARDA...LGAVVVSNERLFA.....ELDMDRFF.Y.SVRPY...............FKPHRVG.QHVYRGANAGDFAGINVIDMLLGLC.R...A.....D...H..AY...YSQLLVDKFLYMMPEDQVILRDCMRRRSLMDDFLALD.E.D..E.RR....rEP..CRENLALFLELCELH.GQ.TAAQHHDQLVAKFIEEPAQHMDQEHHDK......LTASGPPLPVLLRALARL.R.D.L.RQAAD.RDDIPSRYADIRKLRESL.................................................................................
Q3IDE5_PSET1/2-388 ..................................................s-THTAIFDRWIRSAFPQINSELEQLYWQ.QDDK.ANV.E...G..L..GEPLKQQLKDEGNALISNLLAE...GNTD...EGFD.SAFDLLGNVGLFMAACRRH..EITEP..SRETTSPLVEA.S..ALAMHIGASIGVTPRFATAHLTTHNKALNGTYKRFTNLPDEKLFIDYNTQGILAYKRASDALL..KI..LP.LGISHPTCAELLKVAKQA...LIDVIESNNALYT.....QLDTERFF.N.CVRPY...............YKPHRVG.NEIYRGANAGDFAGINVIDMLLGLC.S...A.....N...E..PS...YSQMLVDKFLYMMPEDQQILREAMRMQSFMDDFLQAQ.Q.Y..K.DN.....DW..FKYHAKLFIQVCKLH.GD.TAIGHHNQLVEKFIAQPSKQMQQQHMSK......VTASGPPLHVLLDSLEKL.R.D.K.RASAK.RDDIKTRYDDINLLKQW-i................................................................................
A0A0F7FU76_9ACTN/30-366 .........................................dadracfdlr---------------------------R.QNET.ADV.R...A..L..TAALRTLLPDADAL--------...--AG...YSVE.ESVAAMRDLGLFLGSVKRH..G-PEP..LD--LVPEALP.V..LREL--GRRTDMVPRDTVHHYCTWNPL-GTRQRMYTGDVQEAYLQESVRMVFPHLRDGLELAA..VL..GD.TDLADPKFALLTDELSRH...TESTVTAIDMVVA.....NVGPEFFA.R.VLRPY...............FEEIDVG.DRVLLGPAAAQVP-LWLIDLAIWAA.D...H.....S...E..PG...YQEFLRESIPYSLRRWRDLYGRWIRTPSVVGRLVEAF.G.E..D.PG.....EA..ERRAPAL------RA.ST.EALARLLRVLVVFRGRHLGIARKAYDADlr..lyPVGSGGASVDLLRQIIDL.T.-.-.RAAAQ.------------------ltqpgt...........................................................................
A0A7L4Y877_9ACTN/24-373 ...........................iraadplgadallaalpgmnadad----------------------------.----.--V.A...A..L..TVALRTLVPDPDRA--------...--AE...WSVV.DALAAMRDLGILLGSLKRH..GI-QP..VA--AVPEVLP.V..-LEL-LGRRTDMVPRDTVHHYTTWNPL-GPRQRMYTGHPMEAHLQEAVRMAFPGLVAALDTCS..RL..AR.LEPYDPGFAVALDRTAHH...VQSMVDSIDFTIA.....HVSPEFFA.L.TLRPY...............FEAIDVA.GRDYLGPAAAQVP-LWLVDVTLWQC.D...R.....S...H..SA...YDEFLADSVQYSLPSWRDFHARHAGGVSAVSKLSAAV.S.W..E.NV.....DR..LPPQLAA--------.SA.HALGRVLRILKTFRARHIGIARRAYSDDlr..lyDEGSGGAPVDLLRSILDL.TrD.N.ETLVR.R-----------------atgtrsrvrp.......................................................................
A0A542QNV9_9ACTN/22-371 .....................................aeiraadplgadal------------------LAALPAM---.-NAD.ADV.P...A..L..TVALRTLVPEPERV--------...--AA...LGIT.DALAAMRDLGILLGSLKRH..G-VEP..VA--AVPEVLP.V..LEEL--GRRTDMVPRDTVHHYTAWNPLG-ARQRMYTGDIMESHLQDAVRMAFPSLVAALDTCA..QL..AR.CEPYEPGFALALDRTAQH...VQSMVDSIDFTIA.....NVSPVFFA.T.RMRSY...............FEEIDVG.GTDYLGPAAAQVP-LWLVDLTLWQC.D...R.....S...N..PA...YDAFLDDSVRYSLPSWRAHYAAHKAGTSAVSKLSAAI.S.W..E.AA.....HR..LPPQL--------AA.SA.VSLARVLRILKTFRARHFTLARKAYSEDvr..lyDVGSGGAPIELLRSVLDLtR.D.N.ETLVR.RST---------------erprtp...........................................................................
A0A8J3ZXS5_9ACTN/1-378 ...............................................manp----VEFDRWLDDEFVELNTELEEAYFA.ARAE.-IV.R...GdpD..LDARREAILFDGAKLAAGVLDA...GELP...DDPV.ARYQLLGSVGGYLGAVRRH..QIDTG..HADVLAP---A.W..TLAWTLAAPLGVAPRYVFAHQCLYG------HRLFTALRDERIFVTYNALGVLAYRRAAHALR..QI..PP.MGVSTPMTGYLLADARTA...LEDVLRFNRLLAA.....ELDVDRFF.F.NVRPY...............FKPYRVG.TKEYRGANAGDFAGINEIDLLLGLC.R...R.....D...D..PF...YARILAEKAPYVPPEDQAPLRVAGTGPSILDQFLAAA.N.A..G.RL....tGE..LKQNAATFLDVCRAH.GA.AYSFHHNRLVRPYLVEPAGRSP--DAED......LTASGPPLPVVLEFLERL.S.D.L.RAARN.RPDLRTAHGDLRALRAA-v................................................................................
A0A0Q0H8X1_9GAMM/5-391 ...................................................TRHTQAFDEWIRHRFVALNDQLEQAYFE.QADK.NNV.E...G..I..GDDIKQMLLTQGNDLISHLLEE...GNTD...QGFD.SAFDLLGNVGLFMAACRRH..EITEP..SRETYSPLKQA.S..ALAMHIGASIGVTPRFATAHLTTHNRALNGTYKRFTSLEDEQIFVDYNTKGILAYKRAADALL..KI..QP.LGISHPICFDLLTVAEQA...LSEVIDSNSRLFN.....KLDADRFF.Y.CVRPY...............YKPYRVG.SQVYRGANAGDFAGINVIDLQLGLC.A...A.....N...D..QS...YSQLLVDKFLYMMPEDQRILRDCMRRQSIMDDFLLQR.S.A..S.QQ.....GW..YQKNLQQFLVVCQRH.GQ.GAIQHHDQLVSKYISQPSTDMAQQHMAK......VTASGPPLPVLIAALEKL.R.D.R.RAANK.RDDIHTRFDDIKTLQASL.................................................................................
A0A3A4BCG6_9ACTN/18-394 ................................................gpa----ALYDQWIRREFVEYNTALEEAYFA.AGRE.L-V.T...GrrD..LEEIKEALAREGAELIGRLAGD...GSVP...ADPE.ERYELLGRVGFYLAALRRH..EVEAP..-------DPSA.G..VLSQVLGTSLGVAPRYVFAHQSLYNRAVRDAYPTFTSLPDEHVFVTYNGLGVLAYQRAAAALA..PI..PA.LGVSSPLATYLLEGARAA...LDDVLAFNRALSG.....ELDPGRFF.L.NIRPY...............FKPYRVG.GVEYRGVNAGDFSGINEIDLLLGLC.D...A.....R...D..PF...YQRVLAEKRPYVPPEDQGRLSRAVMIPSLLDAFLAEM.D.A..G.PL....pPR..LRRNAELFLAVCRSH.GA.AYTFHHHRLVKPFLETPAQNAE----GE......VTSSGPPLEAVIAMLDRL.S.D.L.RSARR.RPGLTSASASLDRLRRAL.................................................................................
A0A2N3Y4Z1_SACSN/14-351 .....................................ddehirhldpldfd-------------------IRLPSL-WE.ANAA.GDV.R...A..L..LAILNDILPSLETT--------...--KA...MSLP.ESVATIRDLGIVMGSVKRH..G-VEP..VV--AIPELEA.P..LRAI--GERTGMIPRDTIHHYIRWNPTG-RRERMYTGEPMEKLLMASVRISLPRLSAAVDVCT..AL..HT.AEAGDLDFALAANELAAL...VGAMEDSIDTVIA.....DVTPEFFA.R.TIRPY...............FEDIRIG.EDTFLGPAAAHVP-LALVDLLLWAS.D...H.....S...D..SE...YLKFVHESAIYGLEHWRPLYQEWGNAPSLAARVIGAL.E.R..G.P-.....--..---------------.--.----------------------------......------------------.-.-.-.-----.------------------kgevplamhasvealcrtlrslmvfrgkhltvarkayadevrlyelgsgggsiglltnitslvkgm...............
A0A7K1Y8W7_9SPHI/2-386 ..................................................t-PNVSRFDRWIRTSFVEINTELETLYFA.QENK.AAV.T...F..T..GAALKQQLLAEGCAFIIDLLNE...GNTD...EGFE.EGFNLLGNVGLYLAACRRH..EIDEA..NQ---NIMKEA.S..SLALQLGASLGVTPRFATSHLTTHNTAFNGRYKTFTSLEDEAIFIDYNTRGIFSYKRAADALL..RI..MP.LGVSHPVAPDLFKAAKDA...LYDVIAYNKTLFK.....KLDTDRFF.Y.NVRPY...............YKPHRVG.ASVYRGANAGDFAGINVIDLLLGLC.R...A.....E...N..AS...YSQMLVDKFLYMMPQDQLLLRDCMRQKSMMNSFLEAL.P.A..N.SK....sPW..FQENLKAFLDVCDAH.GE.AAAQHHDQLVGKYISQPAVNLPEENHSN......LTASGPPLPVLLAVLEKL.R.D.Q.RMAAP.RNDIETRYKDIQLLKAA-i................................................................................
A0A4R7V2M0_9PSEU/1-149 ..................................................m----------------------------.----.---.-...-..-..----------------------...----...----.-------------------..-----..-----------.-..---------------------------------------------------------------..--..--.------------------...-------------.....--------.-.-----...............-----VC.GTEYRGANAGDYSAVNEIDLALGLC.D...L.....T...D..PF...YQRIVAEKYPYVPPEDQPRLRTP---PADLRHRLAPG.G.-..-.--.....--..--PNTDRFLAVCRAH.GA.AYAFHHHRLVKPFLQAPAATVPPDRLAK......LTASGPPLDVVVATLARL.V.D.L.CTARS.RK----------------hrqdsrlst........................................................................
A0A166XFK5_9GAMM/2-388 .................................................tq--LTKDFDIWIRNDFVELNDRLEAAYRD.QSDR.ANV.E...G..V..GEDIKQQLLLQGEQHIEALLAE...GNTD...EGFD.SAFDLLGNVGLYMAACRRH..EITEP..SRELYSPLKAA.S..ALAMHIGSSIGVTPRFATAHLTTHNSAIDGVYKRFTSDPAEQLFIDYNTRGILAYKRAAEALL..KI..QP.LGISHPMTPVLFEEVKRA...LLDVIGSNQTLFK.....QLDTESFF.Y.VVRPY...............YKPYRVG.KEVYRGANAGDFAGINVIDMMLGLC.R...A.....N...D..VD...YAQILVEKLLYMMPEDQATLRECMRLPNLMDAFLEAQ.T.Y..R.NQ.....AW..YQESLSVFLQACKLH.GD.TAIQHHNQLVEKYICHPAKFMASNHLEK......VTASGPPLEVLLKQLETL.R.D.K.RAAAK.RADLETRFADIQQLRSTL.................................................................................
A0A1M5Q393_STRHI/40-368 ..............aalpemnarvdvpeltralralisvyherpprdtvgr----------------------------.----.---.-...-..-..----------------------...----...----.--LAAMRDLGMLLGSLKRH..G-VEP..LA--AVPEAEG.P..LLAL--GAATDMVPRDTVLHYGAWNPR-GPRQRMFVGAAEESVLIDAVRRTAPAVEDAALTLV..SL..AG.TEVRDPRFARSCRHAVAR...LAVLPAVMRVVGQ.....VVDPARFFlA.RLRPY...............MEDVEIA.GRHYYGPAAAHVP-LHLLDRVVWSG.D...R.....G...D..PA...HSALQDDLIDYGLPSWRRVFAGSKGRETLVTRVIRAV.G.-..-.--.....--..---------------.--.----------------------------......------------------.-.-.-.-----.------------------pagapdpelrpavealtdllrtlvvfrgrhsplvkaaytrnenyfagsagaspdvvrhilaltrqcadglralaar.....
A0A4P6U8C4_9NOCA/16-362 avqaadplnadvlltdlaamneradttalwalqrelthrtltllaarslsg----------------------------.----.---.-...-..-..----------------------...----...---V.ESLAVMRDIGIVLGSVKRH..G-TEP..LE--VTPDLSP.A..LLAL--GWQTGLIPRDTVQHYTAWNPR-GERRRRYTDDPQEQHLQDAVSTVFPQLSASLTISS..EL..SE.LDPRDSRFAPLMSCLDGI...TVSMVTTIDTVVR.....SVSPVFFA.Q.VLRPY...............FEEITIA.GTTYLGPAAAQVP-LWLVDLCLWAS.D...R.....N...A..DG...YRKFLDDSLPYALPSWRAFHDAHHRHPSIVTRLTTGF.A.A..E.PQ.....--..-NADLER--------.SA.EATARLLRTLKTFRGRHIGIAKKAYADDvr..lyENGSGGAPVALLKEILDL.T.-.-.-----.------------------renetllnkpttshr..................................................................
A0A2W2KKV8_9ACTN/44-276 .....................................llarrsaevlsaap----------------------------.----.---.-...-..-..----------------------...----...----.-AQAALRDLGMLTASLARH..TGH--..--SAPAPCVEA.A..LLRL--GALTGEVPRETVYSYATRNPR-GLRRRSFTDTPGEHLFIDEVTAASHTLEAAIDLLV..HL..PK.ADNETA-ATALADQVAQH...LRAFSTHLLRVKR.....NLTPEFFT.G.QLRPY...............YPPLEIA.GRTYYAPGGAQMP-LLVVDVLLLAQ.A...S.....T...G..PLarwYAQYVAGNVLYLPPHHRALIEDAGSRPGL--------.-.-..-.--.....--..---------------.--.----------------------------......------------------.-.-.-.-----.------------------arlarhaahlr......................................................................
E1SN32_FERBD/2-389 .................................................ns--KVAAFDGWIRSDFVTLNNELEALYFE.QDDK.ANV.A...G..I..GEHAKQQLEAQGREHIQTLLAQ...GNTD...EGFD.RAFDLLGNVGLYMAACRRH..GLSDP..DRDSSSPQQEA.S..ALAMHIAASIGVVPRFATAHLCTHNRAVDGQYKRFTDLTDERVFVDYNSKGILAFKRAADALM..RV..LP.LGVSHPIARDLFHACADA...LEEVKESNRVLFN.....TLDPERFF.Y.CVRPY...............YKPHHVG.GQVYRGANAGDFAGINVIDMLLGLC.Q...A.....N...E..PS...YGRMLVEKFLYMMPEDQAILRDCMRRQSLMDEFLAVApE.H..H.GS.....SW..YQENLSAFLRLCELH.GE.IATQHHNQLVHTYIVRPSEQMDQKHMGQ......LTASGPALQGLLKALTDL.R.D.R.RAGAP.REDILTRYNELAHLRASL.................................................................................
A0A4V2ELC1_9PSEU/91-343 .................................................yl----------------------------.----.---.-...-..-..----------------------...----...----.-------------------..-----..-----------.-..---------------------------------TFTSLPDELLFVVRNGLAVLAYQRAADALR..RI..PP.MGVSSPLATYLLETARAA...LDDVLEFNRGLAE.....ALDVDRFF.L.NVRPY...............FKPYLVG.TTEYRGANAGDFAAVNEVDLLLGLC.A...A.....T...D..PF...YAGVIREKTPFTPPEDQAALRAAVTGDLLLDMFLRET.A.L..D.PV....pPR..LRRNTELFLEVCRAH.GA.AYIFHHHRLVRPFLEAPAKWTPPERLAT......LTASGPPLDVVIAQLERL.S.D.L.QAGRD.RPGLSTARASLNCL----leri.............................................................................
A0A1C5GAZ2_MICEH/1-346 ............................................mttsfig-----------------ADQNADDLAVA.AMDP.LRA.D...D..V..LAELPAANERADTAWMADALADlgaGFDT...ADVY.TARAALRDLGFLAASLIRH..D---P..DA--DLNGIEP.T..LLRL--AAVADEVPRDTVYSYTTRNPV-GPRRRGFLLSDEEHVFIDSVVAATQALNLAVDDLA..AC..RDsADLDEDMLLAALGQVHDG...VEVLRKNLRTVQR.....TITPDYFS.N.RLRPY...............FPSMSLG.GRAYMGPGGAQMP-LLVLDVLLLAP.S...E.....P..gQlgAW...HDGYLGENVLYLPPTHRAVCDDT--------------.-.-..-.--.....--..---------------.--.----------------------------......------------------.-.-.-.-----.------------------llayrsgnspllrcllesprvraeyaallkrilrfryphrqvaranmairaegslgsggytvealdhlieittskaavtlp
A0A4U1B922_9GAMM/5-391 ...................................................TANTRAFDQWIRNEFCQLNSELESLYWQ.QDDK.ANV.E...N..L..GDDLKQTLTTEGNALITSLLAE...GNTD...EGFD.NAFNLLGNVGLFMAACRRH..EITEP..TRETVSPLTEA.S..ALAMHIGASIGVTPRFATAHLTTHNSAINGVYKRFTDLPDEALFIDYNTKGILAYKRAADALL..KI..QP.LGISHPITADLLKVAKQA...LQDVLDSNQILFE.....RLDTDRFF.Y.CVRPY...............YKPYRVG.KEVYRGANAGDFAGINVIDMQLGLC.F...A.....N...E..PS...YSQMLVDKFLYMMPEDQTILRDCMRRPSLMDDFLAAK.D.A..H.RQ.....QW..YQENLQLFLDVCKLH.GD.TAIAHHNQLVEKYIRVPSMSMMQQHMDK......VTASGPPLPALLDGLEKL.R.D.K.RCAAK.RDDIRTRYQDIEDLKQTL.................................................................................
F2JUA2_MARM1/3-386 ................................................tpl---VNEFDNWIRTRFVDLNTELESLYFA.QDKK.EQI.Q...G..V..GEELKLALITEGDQFVQQLLHE...GNTD...EGFD.SGFDLLGNVGFLMSASRRH..E----..MDEKHPALKSA.S..ALAMQLGASLGVVPRFASAHLETHNRAQNGKYKTFTHLDDEKVFLDYNTRGVFGFIRASEALL..HI..LP.LGVSHPVTLDLLNTAKDA...LEKVVENNTALFN.....ELDVDRFF.Y.NVRPY...............YKTHKVG.RHEYRGANAGDFAGINVIDLLLGLC.R...G.....N...D..PY...YSQLLVDKFLFMRPEEQLTLRDCMRRTSLMDEFLAVS.D.E..E.RE....sQW..FKINLSAFLDVCEAH.GE.TARQHHSQLISRFIESPAAKYELAHRQD......MTASGPPLEVLLAALQKL.H.D.L.RTASY.REDIQTRHQDVQTLRSY-l................................................................................
V6KCF9_STRNV/25-370 ........raadplgadatvaavpamnrdadipaltvalrtlvpdhdrtas----------------------------.----.---.-...-..-..----------------------...----...LSVV.DALAAVRDLGLLLGSLKRH..G-VEP..LA--AVPEALP.V..LQEL--ARRTDMVPRDTVHHYTTWNPL-GDRQRMYTGERMEGHLQNAVRMVFPALVAALDTCD..EL..AG.LEPYDPRFADTLDRTGQH...VQAMVDSIDFTVA.....QVSPEFFA.R.GLRPY...............FEEIDVA.GRDYLGPAAAQVP-LWLVDLTLWQS.D...R.....S...S..PE...YDAFLDESVLYSLPSWRAFHAAHRGSTSAVSKLSAAI.S.W..E.ST.....PR..LPPVLAA--------.SA.VSAARVLRILKTFRARHIGIARKAYSDElr..lyDAGSGGAPIALLRSVLDL.T.-.-.-----.------------------rdnetlvrhanvrmha.................................................................
A0A4V2ELC1_9PSEU/2-93 .................................................tg--EIGRFDRWLRHEFVDVNTELEEAYFA.ERS-.EII.H...G..VpaLESAKGALERDGADHIAAILDN...ASLP...AGDQ.ARYQLLGKIGLYLAACRRH..E----..-----------.-..---------------------------------------------------------------..--..--.------------------...-------------.....--------.-.-----...............-------.-------------------------.-...-.....-...-..--...-------------------------------------.-.-..-.--.....--..---------------.--.----------------------------......------------------.-.-.-.-----.------------------ylt..............................................................................
A0A4V5NWG0_9GAMM/2-389 ..................................................s-QNVAQFDAWIRDQFKALNTELESLYDH.CENP.MQI.A...D..T..GNELKQQLKQEGESHIEKLLIE...GNTD...QGFD.RNFDLLGNIGMYMAACRRH..ELTEP..SRETRSPLEKA.S..ALALQVGASLGVTPRFATSHLTTHCKAVDGEPKRFTSLKDEALFIDFNTLAVLAYKRAADALV..RI..LP.MGISHPVAPYLLMDATSA...LKDVAHWNKKLFD.....ELDGDAFF.N.HVRPY...............YKPFRVG.QHEYRGANAGDFAGINEIDMLLGLC.Q...A.....N...Q..SF...YSQLLVDKFLYMMPEDQARLRDVMRRQSLLDQILDGL.N.S..N.PE....aPW..LKEVIQALVEAIDAH.GN.TAHQHHEQLVKRFIVAPSIKLEDNDKTH......ITASGPPLEVLLRSLNRL.K.E.L.RMAAN.NSQLPSRYHDVQRLKCW-l................................................................................
E3BJD8_9VIBR/2-389 ...................................................TENTWKFDEWIRTQFVEHNNELECLYWQ.QSDK.ANV.E...G..I..GEEIKKSLVEQGNYYISKLLQE...GNTD...EGFD.ADFDLLGNVGLFMAACRRH..EITEP..SRERVSPLHEA.S..ALSMQIGASIGVTPRFATAHLTTHNRAVNGRYKRFTDLDAEKLFVDYNTRGILAFKRAADALL..KI..KP.IGVSHPMAEDLFKVAYQA...LADVYQSNEILFS.....ELDSDAFF.Y.QVRPY...............YKPYRVG.QHIYRGANAGDFAGINVIDLLLGLC.L...A.....N...E..SS...YSQLLVDKFLYMMPEDQRILRDCMRMTSLMDEFISVM.DrS..R.HQ.....VW..YKKHLALFLSVCEMH.GK.TAQQHHNQLVEKYIAVPANSMNQEHMDK......LTASGPPLNVLLGALEKL.K.D.R.RNAVK.RDDIVTRFDDIQKLKHSL.................................................................................
A0A8J3ZGI1_9ACTN/9-381 ...............................................evss-----EFERWLDGEFVELNTQLEEAYFR.AHVE.-IV.R...GdpD..LDARREAILFDGAKFAAAVLDA...GDLP...TDPV.ARYQLLGSVGGYLASCRRH..QIDKG..HAEVLAP---A.W..TLAWTLAAPLGVAPRYVFAHQCLYG------HRLFTSLDDERIFVTYNALGVLAYRRAAHALR..QI..PP.MGVAAPMAGYLLADARSA...LDDVLRFNTQLAA.....ELDVDRFF.Y.NVRPY...............FKSYRVG.TAEYRGANAGDFAGINEIDLLLGLC.R...R.....D...D..PF...YGRILTEKAPYVPPEDQEPLKAAGTGESILAQFQR-A.G.R..T.DQ.....--..VRENARIFLDVCRLH.GA.AYSFHHNRLVRPFLVEPAEHAPDA--ED......LTASGPPLPVVLEFLERL.G.D.L.RAARN.RPGLATAHGDLARLRESL.................................................................................
A0A0F4PQL1_9GAMM/2-389 .................................................tp--HAQQFDDWIRSRFVEINNQLEQRYQA.QADR.ANV.H...G..V..GDALKQQLTDEGDALIANLVDE...GNTD...EGFD.SAFDLLGNVGLYMAACRRH..EITEP..SRETHSPLQQA.S..TLAMHIGASIGVTPRFATAHLTTHNRAINGQYKRFTDLPDERLFVDYNTKGIVAFKRAADALL..RI..QP.LGISHPVVPDLLLVAEQA...LKDVLESNRYLFQ.....HLDAQQFF.Y.AVRPY...............YKPYRVG.KEVYRGANAGDFAGINVIDMLLGLC.C...A.....N...E..PA...YSQMLVEKFLYMMPEDQRVLRNCMRLPSIMDEFLAVA.P.Q..Q.HS....sSW..FQQNLRAFLRVCKLH.GQ.TAIQHHNQLVDKYIRIPNENLGSQHQTK......VTASGPPLPVLLAELANL.R.D.K.RAARE.RDDIHTRYHDIATLTA--lv...............................................................................
A0A4Q0YII9_9GAMM/2-389 ...................................................TDNTLAFDAWIRNEFVEHNNALEALYWK.QSDR.ANV.V...D..V..GGDIKASLVEQGNQFISQLLQE...GNTD...EGFD.AAFDLLGNVGLFMAACRRH..EITEP..SRESFSPLREA.S..ALSMQIGASIGVTPRFATAHLTTHNQSINGTYKRFTDLDAEKIFVDYNTRGIFAYKRAADALL..KI..KS.IGISHPIAADLLLVAHQA...LKDVYESNEVLFS.....ALDTDAFF.Y.QVRPY...............YKPYRVG.QHVYRGANAGDFAGINVIDLLLGLC.L...A.....N...E..SS...YSQLLVDKFLYMMPEDQQILRDCMRMTSFMDEFLSAT.E.Q..Q.SN....aSW..YQQHLALFLDVCDMH.GR.TAVQHHNQLVEKYIAKPAATMEETHLDK......LTASGPPLHVLLGALEKL.R.D.R.RNAAE.RSDIFTRFNDIQSLRNSL.................................................................................
A0A7K3GM81_9ACTN/51-350 ..........................................rvaanvrdt----------------------------.----.---.-...-..-..----------------------...----...---V.TAGAALRDLGFALASLERH..G----..VDLRRVPGAEE.T..LLRL--GALTGEVPRDSVYTYALRNP--ENAVRSFTELPEEALFIREVRTAGVALRPAVDALL..EA..LP.LTAEDPGLPELLAEATRG...FTVFAQSLLAVKR.....AITPQTFS.G.ELRPY...............FPPMTVG.GQVLYAPGGAQMTPLL-VDILLIRP.EpgdQ.....A...E..EW...YEGYLRENLPYLPAAYRAASDRARRHRPLLPRLVDEA.T.A..H.SP.....-V..RPTAGRA------LA.GL.RSLMR---ELLRFRLPHLQLAKANMNIRp...dgSLGSGGYTTDSLDHLAEL.T.L.A.R----.------------------hrllsg...........................................................................
K0F9H5_NOCBR/20-344 ....................naaadlrqlatmfrellsrarevelpeiadr----------------------------.----.---.-...-..-..----------------------...----...----.--LAAMRDVGMLMSSLRRH..G-VEP..LD--AVPEAAG.V..LLAW--GHSAGMVPRDTVLHYGAWNPR-GKRQRMFLGEQQENVVLDAVRVSTLLISEIAPQLA..GL..AE.LHPDDTAFGEICHAAADQ...LETLPQLMSGLYR.....TVDPIEFY.AaRLRPF...............MADVVVA.DRSYYGPAAVHVP-LYLIDRLVWSS.D...H.....G...G..VG...MTYFQDDLLNYGLPRWRRMFEHTADAESLVTRLVREF.D.R..P.DG.....PP..STKAAYA------MD.G-.-VIRILDGL-VTFRTKHGMLARAAYTDGt...ryAMGIAGVSPAVLDHVLAL.T.-.R.RCA--.------------------nwartrrrga.......................................................................
A0A2K5R2R7_CEBIM/160-387 ...........................lvsllveieaasaikamrmqelda----------------------------.----.---.-...-..-..----------------------...----...----.-------------------..-----..-----------.-..---------------------------------------------------------------..--..--.-------LRKALLKIASC...LEKALQVFHQIHE.....HVDPQVFF.N.VLRIYlsgwkgnpqlsegliYDGFWKD.AKQFSGGSAGQSSIFQCFDVLLGIPqR...A.....S...G..GS...AAQFLQDMRMYMPPAHRNFLCSLESKPSVREFVLLKD.D.A..D.LR.....EA..YDACVKALVNLRN--.--.----YHLQIVTKYILIPASQKSKDKTSQepseqgN--KGTGGTDLMNFLK--.-.-.-.-----.------------------tvrtttqksll......................................................................
A0A6H1UFU1_9GAMM/2-389 .................................................nd--TVAAFDDWIRTDFIELNSELERRYRQ.QQDR.ANV.V...G..V..GDEVKAQLEAVGCEHTKLLLAQ...GNTD...EGFE.QAFDLLGNVGLYLAACRRH..GLSDP..DNDRTSPQAEA.S..ALAMHIAASIGVVPRFATAHLCTHNRAVNGHYKRFTNLAAEQCFIDYNSKGILAFKRAAEALL..KV..LS.LGISHPISLNLFDAAKHA...LEEVYHSNDTLFT.....QLDPDDFF.Y.GVRPY...............YKPHHVG.SQVYRGANAGDFAGINVIDMLLGLC.K...A.....N...E..PA...YGRMLVEKFLYMMPQEQRILRDCMRQQSLMTEFLEVA.P.K..Q.HH....sRW..YQQHLQAFLKLCQLH.GE.IANQHHQQLVQRYIVQPAAQMEQQHLQQ......LTASGPQLAGLLQSLTDL.R.D.R.RAGYQ.RDDIVTSYRELSLLRRTL.................................................................................
A0A1H2S9V3_9PSEU/2-383 .................................................tr--TITDLDRWIRGEFTGLNTKLEEIYFA.EKTLvLRG.R...A..E..VDDLTTTLVRDGGALIGKITEQ...RQLP...EHAD.ARYELLGMVGFYLAACRRH..E-VEP..DQAQFAPL---.-..ALAL--GASLGVAPRFAASHQNIRNRAVGGAFATFTTLDSERIFLLYNGLSVMAYRRATHALL..SV..PA.LGVSNPLATYHLTDAVAA...LRDVLRFSQALAN.....ELDKDRFF.Y.NIRPY...............FKSYRVG.SQEFRGVNAGDFAAVNAIDVLLGLC.S...P.....H...D..PF...YQGVITEKYPYVAPEDQELLRSLVTTESLMDMAVREL.E.A..G.PP....pAS..LHGNAELLLDACRGH.GA.ATVFHHNKLVAPFLREPAGYAPPEDQAD......MTTSGSPLDAVIEALARL.R.D.L.RAAHD.RPGVVTARSTLDRVRAL-l................................................................................
A0A365H9F2_9ACTN/31-412 .................................................aa--AVDRFDRWIRQEFVERNTELEEAYFS.ARRE.IVH.D...P..H..LDTIKRMIRTDGAKLIAPIVED...GGMP...PGAQ.ERYRLLGAVGFYLASCRRH..EVDGP..DG--AEELSAA.W..SLANLLGSSLGVVPRFVFAHQSFYNPAVHDAYRTFTSLDDESVFITYNALAALAYRRAAHALR..SV..PP.MGVSNPMATYLLEDARAA...LDDVMEFQRTLGR.....TLDVDRFF.F.NVRPY...............FKPYRVG.GTEYRGANAGDFSAINELDVLLGLC.D...P.....R...D..PF...YQGILAEKRPYLPPEDQARLRGVVTAESLLEAFLREA.A.A.gP.VT.....PR..LRENAEHFLALCRAH.GT.ASSFHHHKLVKPFLEEPARDAPEERRKG......ITASGPPLEVVMAWLARL.S.D.L.RAAR-.------------------dlpgsarlalerlrn..................................................................
A0A1G8XRS6_9BACT/26-369 ..................................sldplqsddrltrvpaf----------------------------.-NKE.RDV.M...A..L..VMTLQDMLPAVQEV--------...--TT...FDYP.QACAAMRDIGILLGSIKRH..G-VEP..VH--VVPSLED.R..-LNL-LGEVTNLPPRDTLIHYVRWNPEGSR-LRTYTGTEDEHQLIKSVQVAFHPLYEAILSLH..DL..YH.VSLDSSEFSTLCDQVISQ...FEGMVHGVVNAKR.....NVSPQYFA.E.ELRFY...............FDPIQLN.GREYLGPGAVEMP-VFLFDHILWSC.D...V.....E...D..ET...YTAFKKAYVPYNQAMVRDLYAAYEQRPSLVSKAVQEL.S.N..G.DD.....-F..CETRLES--------.-A.KSLVRLFNLLKSFRAPHKKLADKAYEHAakdnyrEKGSGGYEPGVLHYILQL.N.-.-.-----.------------------lnalqnlkariqvye..................................................................
A0A1I0HZ79_THASX/2-388 ...................................................TENTLAFDQWIRTRFVELNTELELLYKQ.QNDR.ANV.V...G..I..GDNLKQTLEQEGNALIAKLVSE...GNTD...EGFD.AAFDLLGNVGLFMAACRRH..EITEP..SRERTSPLVEA.S..TLAMHIGSSIGVTPRFATAHLCTHNKAVDGKYKRFTDLIDEKVFIDYNTKGILGFKRAADALL..KI..LP.LGISHPISLDLLQCAKVA...LEDVLSSNQTLFD.....TLDDDEFF.Y.AVRPY...............YKPYRVG.SQVYRGANAGDFAGINVVDMLLGLC.F...A.....N...E..QS...YSQMLVDKFLYMMPEDQQILRDCMRRTSLMDEFLAQA.K.H..A.NQ.....PW..FQQHLSMFLSVCEAH.GE.TAIQHHNQLVNKYIEKPAEVMESQHLEK......VTASGPPLSVLLNSLEKL.R.D.R.RCAAD.RDDIRTRFQDIHSLKALL.................................................................................
A0A4U1L7V8_9SPHN/5-392 ..................................................s-QATLAFDRWIRTAFPQMNEALENLYFE.QDDR.ANT.Q...G..I..GDALKAAIRDEGHGHIVALWRE...GNTG...EGFD.SAFDVLGNVGLYMAALRRH..ELTNP..AREDRSPFAEA.S..SLSLHLGASIGMAPRFATAHLAHRNRAVAGVRKSFTFLADEFLFIDENARGILCLQRAADALF..RI..VP.LGVSNPVADVQFEAAAHA...LDQAIAINARLFA.....ALDVERFF.F.SVRPY...............YKPYRVG.RQEYRGANAGDFAGINELDLLLGLT.R...A.....S...D..PH...YAQLLVDKMLYMLPEDQARLRDCMRHRSLLDELLLLA.D.D..H.AA....aPW..FQAALGGLLGVIDRF.AE.TARQHHALLVDRFIAGPAATLDRAHMAG......ITASGPPLDALLRALQLL.H.D.F.RTAAP.RSDVETRHADLARLRALL.................................................................................
A0A6G9H4K2_9ACTN/16-363 .....................................atvreldplaadpa---------------------LSAL-RE.QNAR.ADV.P...A..L..AAALRGLVPALDAV--------...GA--...YSAE.RCAAAMRDLGLFLGSIKRH..G-PEP..LS--LVPELRP.V..LLEL--GRRTDLVPRDTVHHYCTWNPV-GERQRMYTGDAQEARLQESVRLVFPHLRAGIELAA..TL..SD.TAPDDAQFRRSAEELTAH...VERIVTAIDLVVA.....HVTPEFFA.L.GLRPY...............FEEITVG.DRVLMGPAAAQVP-LWLIDQALWAS.D...H.....S...E..PA...YAEFVRDSVPYALPRWRDLYARWSRVPSVVSRLVEAF.G.D..N.PD.....DA..ARRMPAL------RA.NS.EALARLLRVIVVFRGRHLALARKAYDADlr..ryPVGSGGGSTDLLRQILDL.T.-.-.RTAAR.------------------lttrpads.........................................................................
A0A1H8Y654_9PSEU/1-377 .................................................md-----RLDRWIRTEFVEYNTALEEAYFA.ERRE.IVCdR...P..E..LEKIKQAVVIEGGRLIGAV--S...GPLP...ISPR.EKYQLLGMVGFYLAACRRH..ESAEP..VD----P--SA.W..SLAQQLGSALGVAPRFVFAHQALYNPAVRDRYQTFTSLADEAVFLTGNGLAVLAYQRAADALR..RV..PP.MGVSNPLTTYLLETALSA...LDDVLRFNRDLGK.....TLDVDRFF.F.NIRPY...............FKSHRVG.AVEYRGANAGDFSAINEIDLLLGLC.D...A.....R...D..PF...YQNVIAEKYAYVAPEDQVLLRAVVDEEPLLAKFLREA.E.S..G.AG.....PR..LRQNAELFLAVCRAH.GA.AYTYHHHRLVKPFLVAPAEKAPADRLTG......ITASGPPLDVVVAGLSRL.S.D.L.RSARD.RPGVPTARPSLDRLRS--lv...............................................................................
A4ABU7_9GAMM/2-390 .................................................sv--KAQRYDEWIRSSFIEINSELEALYFA.QEDR.ADT.S...A..G..GEALRQLLHDEGRAHIIGLHKE...GNTD...EGFE.AAFSLLGNVGLYMGACRRH..GITEP..SRERSSPLVEA.S..GLALHIGASLGVAPRFATSHLSTHNSASNGVYRSFTKLKDEFLFLDFNTRGIFAYKRAADALV..RT..VP.LGITHPVTADLLLAAHQT...LEDVARYNEQLFE.....QLDPARFF.Y.SVRPY...............YKPYRVG.KSEYRGANAGDFAGINEIDLLLGLC.R...A.....E...D..PS...YSQLLVDKFLYMMPEDQARLRDSMRRKSLMDQILEGL.K.S..P.GSc...gRY..FEENARLFLKVCEAH.GR.TAAQHHDQLVERFIEKPSSALDEKHLTH......ITASGPPLEVLMAALQKL.R.D.L.RTAAP.RDDIQSRYKDIAAIRSAL.................................................................................
A0A0S2K0S0_9GAMM/2-388 ................................................tac---TREFDAWIRSSFCEINSQLETLYWQ.QEDK.ANV.E...D..V..GEVLKQQLQAEGTELIKTLVVE...GNTD...EGFD.NAFDLLGNVGLYMAACRRH..EITEP..SRERTSPLVEA.S..TLAMHIGASIGVTPRFATAHLTTHNTAVNGVYKRFTDLADEKIFVDYNTKGILAYKRAADALL..KI..LP.LGVSHPITGDLLKVAKYA...LQDVIDSNQELFD.....KLDTDRFF.Y.CVRPY...............YKPHRVG.SQVYRGANAGDFAGINVIDMLLGLC.V...A.....N...E..PS...YSQMLVDKFLYMMPEDQQILRDCMRRTSLMDSFLNLE.S.Q..H.SA.....SW..YQENVTLFLEVCELH.GK.GATQHHNQLVEKYIAQPSNSMAEQHLDK......VTASGPPLSVLLGSLEKL.R.D.R.RAANQ.RDDIFTRYHDIQKLKTTL.................................................................................
A0A540WC81_9ACTN/29-348 ....................vnergdlrrlaailtelgeaaaraelftlkd----------------------------.----.---.-...-..-..----------------------...----...----.-RLAAMRDLGMLLGSFKRH..G-TEP..LA--AVPAVEP.L..LLRL--GDETDMVPRDTVFHYGAWNPS-GGRQRMYTGAFEEGVLIESVRVSAMGLERSALELA..AL..DC.LDPADPQYAETLARATES...FMVLPEQIGRVAE.....LVPPAEFFiA.RLRPY...............MEDVAVG.GQTFYGPAAAHVP-LYLIDHLLWSS.D...R.....V...D..PE...HAALQQGLLDYGLPEWGRLHRKRQGCESAVSQVVRAL.L.A..A.GR.....ET..---APQL-----LAS.GH.AVAELLRSLV-VFRGRHLRLVRDAYTVEs...pyTTGSAGAAPEVVK-----.-.-.-.-----.------------------lvldltrdcerqfa...................................................................
A0A7W6G595_9SPHN/2-388 ...............................................spda-----ALNRWIRHDFAAINTALEELYFA.QGDR.AQV.E...G..I..GTDLKAELVRRGEELLAPLLAE...GRTH...DGFD.SALELLGDVGMYLGALRRH..ELTNP..DRETTSPFATA.S..ALALHVGVSIGMAPRFATAHLATHNRAVGGLRRSFTTLHDEFLFIDENTRGIFGLQSAAYALT..RL..VP.LGASSPVADVLFAEAEGA...LKGVAACNARLFE.....TLDIDRFF.Y.CVRPY...............YKPYRVG.RQVYRGANAGDFAGINEIDLMLGLC.R...A.....S...D..PY...YAQLLHEKLPYMLPAEQLRLRESMSRRSILDQLLDHV.E.T..D.RD....aPW..FVANVRAFLGVCDAF.GA.IAAQHHDQLVSRFVAGPAQTMAPGHMQG......ITASGPPLEALLRSLEIL.R.D.L.RMAAP.RGDIASRHDDMARLRAA-i................................................................................
Q8E972_SHEON/5-391 ..................................................t-YNTEAFDEWIRSRFVELNSQLEQLYYQ.QTDR.ANV.Q...E..V..GTELKHTLESEGRELVKALLDE...GNTD...EGFD.SAFDLLGNVGLYMAACRRH..EITEP..TRETTSPLLEA.S..ALAMHIGASIGVTPRFATAHLTTHNRAHNGIYKRFTDLPDEKLFVDYNTKGILAYKRASDALL..KI..QP.LGISHPISHDLLRVTKQA...LQDVIESNQQLFN.....RLDTDRFF.Y.CVRPY...............YKPYRVG.SVVYRGANAGDFAGINVIDLTLGLC.F...A.....N...E..AS...YSQMLVDKFLYMMPEDQQILRECMRRPNLMDDFLQAK.G.C..I.HQ.....DW..YQENLKLFIEVCELH.GQ.TAIQHHNELVTKYIAEPSVSMEQQHLAK......VTASGPPLHVLLASLERL.R.D.R.RAAVL.RDDIRTRYYDLKKLKDSL.................................................................................
A0A1G9Y6N9_ALLAB/42-362 ................................dlrgligmlsdlvrlaret----------------------------.----.---.-...-..-..----------------------...--AD...RPLP.ESLAVMRDLGILLGSVKRH..G-AEP..TK--VVPGLED.V..LLDL--GGRTGMVPRDTIHHYITWNPTG-HRERTYTGDRMETMLLSSVRFSLPQLSAAVDVCR..RL..TS.TDLGSLDFVLAANELVSR...LRPLEDALDTVTA.....NVTPEFFA.R.TLRPY...............YEEIRVD.GARYLGPAAAHVP-LAMVDLLLWAS.D...H.....G...D..AA...YEEFWRESAQYGLPGWPELTEKWAASPSLVTQLKTAA.V.F..M.PR.....GD..FAQNLRA--------.SA.EALARALHALVVFRAKHLAIARQAYAEEnr..lyELGSGGGTVQMLEQVIAF.T.R.E.NA---.------------------tmvrsafvg........................................................................
A0A100Y3K5_9ACTN/37-372 ....................aavpginrdadtaaltvalralvpdldrvag----------------------------.----.---.-...-..-..----------------------...----...WSVV.EALAGMRDLGVLLGSLKRH..G-TEP..VA--AVPEVLP.V..LEEL--GRRTDMVPRDTVHHYTTWNPL-GRRRRSYTGSETEAHLQDAVRMVFPGLVAALGTCG..EL..AR.LEPYDPGFACALDRTAQH...VQSMVDSIDFTVA.....HVAPEFFA.R.TLRPY...............FEGIDVA.GREYLGPAAAQVP-LWLVDLTLWQS.D...R.....S...D..PR...YDAFLDESVRYSLPSWRAFHAAHRGGVSAVGKLTAAL.S.W..E.SG.....HR..TPPAL--------TA.AA.VSLTRVLRLLKTFRARHLGIARKAYHDDlr..lyETGSGGAPVALLRSVLDL.TrD.N.ENLVR.RAT---------------vpprtpa..........................................................................
A3QIX5_SHELP/2-388 ..................................................s-QDVAAFDHWIRQEFVEINSALERLYMQ.QSDP.ANV.V...G..I..GDELKARLEAEGRTLIKALLDE...GNTD...EGFD.AAFDLLGNVGLYMAACRRH..EITEP..SRETSSPLLEA.S..ALAMHIGASIGVTPRFATAHLTTHNRAVNGLYKRFTDLDDEKLFVDYNTKGILAYKRAADALL..KI..QP.LGISHPMTAELLEVALVA...LQQVIASNQTLFE.....RLDTQAFF.N.SVRPY...............YKPYRVG.QQVYRGANAGDFAGINVIDLQLGLC.F...A.....N...E..SA...YSQLLVDKFLYMMPEDQRILRDCMRRTSLMDDFLAAI.E.M..R.DQ.....PW..YQENLAQFLRVCEAH.GQ.GAIQHHDQLVEKYIAQPAKQMESQHIDK......VTASGPPLPVLLGALEKL.R.D.R.RAAAK.RDDIRTRFDDIARLRASL.................................................................................
A0A3M0AI50_9GAMM/2-386 ...................................................TQNTKAFDHWIRTDFVAINTQLETLYFEhHSDR.AQV.E...G..I..GDDLKQQLLNDGRTLLASLLAE...GNTD...EGFD.AGFDLLGNIGFYMAACRRH..ELTEP..SRETKSPLVEA.S..ALALQVGASIGMIPRFSTAHLTTHNQAINGRAKSFTHLPDEAIFNEFNTRSILAYQEASTALI..KV..VD.VGISSPVAIDLLHTAGVA...LKKVFDSNQQLND.....QLDVDRFF.Y.SVRPY...............YKSHRVG.NNIYRGANAGDFAGINIIDLLLGLC.R...A.....D...E..SY...YSQLLVDKMLYMMPDDQAALRNAMRLPNLLDALLSS-.-.-..P.DG.....NW..KAAAATALLKVCRAH.GA.TAEQHHNLLVERFIRVPSQQLAAQHHQN......LTASGPPLPVLLAALEKL.R.D.L.RCASP.RHDIVTAAAKMDQVKEL-l................................................................................
A0A810KXC3_9ACTN/10-370 srlvraldpldadetyrrlpemnaaadvpalvgalrrlaanaaaapdgtpy----------------------------.----.---.-...-..-..----------------------...----...----.ECRAAMRDLGLLLGSIKRH..G-VEP..VT--AVPEVEP.V..LLRL--AARGDVVPRDTVHHYSVWNPY-GERQRSYTGSSQESALIDSVRLSLPRLSQAVELCD..PL..AR.AELTDPEFLTAMGSFRAH...LASLDEAIELVNG.....RVTPAFFA.N.ELRPY...............FDEVTID.GRVWRGGAGAGLP-MPLLDLALWAA.D...HdpdddD...S..AG...YAEFWAGGVPYALPEWRRRYAELAGGPSLVARVTAAL.D.E..A.GD.....GP..MD--DRL------WA.AA.TAVEQSLRALLSFRAKHFTVARQSYQEDvr.lfsVGSSGGSVE-LLASIVRL.T.-.-.RDNAR.------------------vvrprrsarsdperlsr................................................................
A0A089X1U0_STRGA/22-358 ..................................dplgldedlgslpkmne----------------------------.---N.GDV.A...A..L..ARVLREALPPHERI--------...--AS...FTLP.ECLAAMRDLGMYVGSLKRH..GV---..SAFDIVPGATE.-..LFEL-LGRRTRMIPRDTVYHYTCWNPV-GERERLYSGQPMERSLIHAVRTCVPELAKAVTVGR..SL..QY.EDLRTPEGAAGMASLASH...ITAADKAMSGVLA.....DVTPEFFA.L.VLRPY...............FEEVRIA.GRTYMGPAAAHIP-LFLIDLLLWAS.D...R.....G...S..RD...YLAFCDEVASHTLPGWRERHAEWTEMPSITSRVVAAL.G.N..C.RDs...rTP..AGEHARS--------.SA.RGLRRALRSLTAFRGKHLVMARRAYHAEvr..lyERGSGGGSVELLEEILTL.T.-.R.RN---.------------------gamvg............................................................................
A0A8J3INP1_9CHLR/21-334 leqeaainqriaasdplnadvvfqrlpdwnerneseeirqalagiianvts----------------------------.----.---.-...-..-..----------------------...-QLE...WDYT.SCSAAIRDISMLGAALIRF..E-REP..EE-CVSGFSDAlL..ALSTHIGAQI---PRDSFIDYTSRNPSGA-RERTFTSTPQEKIFLNSLRQGMLALDLCLIHLL..TA..CT.FPIASQEFASSVHTATSS...FQAMIAAIVQVKR.....EITPEAFT.H.YIRPF...............FEPFHIA.GKGFSAPSGAEMS-ILNIDQILWGA.D...C.....T...D..EL...YTTYFRANIIRLPTVYQEITQAVVGQKSLLS-LLKER.I.T..-.--.....--..---------------.--.----------------------------......------------------.-.-.-.-----.------------------lgsalnreerrsiqeihqlltrmytfrmphykvaeenv...........................................
A0A2A2Z0G9_9ACTN/7-336 .........................hadvpalvtavrglvpsldevagysv----------------------------.----.---.-...-..-..----------------------...----...---E.ACVAAMRDLGMFLGSIKRH..G-PEP..VP--LVPEVLP.V..LLEL--GRRTDMVPRDTVHHYTTWNPT-GGRQRMYTGDIQEAYLQESVRMVFPHLREGLELAE..RL..SD.SDVADPKFAVLTDELTAH...VETMVSSIDMVVA.....NVSPEFFA.R.DLRAY...............FEEITVG.GRVLLGPAAAQVP-LWLIDQAIWAA.D...N.....S...E..PE...YEEFLRDSVPYSLPRWRELYDNWTGIPSVVTRLVEAY.G.D..D.PD.....--..-GAERRM---PGLRP.SA.EALARLLRVIIVFRGRHLGIARKAYDADlr..lyPVGSGGASVDLLRQIVDL.T.-.-.RATAQ.------------------ltrrpapsaaara....................................................................
A0A364Y1V6_9BACT/20-372 ......qemiqsldplnfdnalpvlhalnregntheiiqllyrhlpvpdrl----------------------------.----.---.-...-..-..----------------------...--DG...FGYE.EAIASMRDLGIFIGILKKH..G-IEP..VD--VLPELEY.V..LLVL--MVKTGLPPRDTLIHYTAWNPS-NERIRTYTGLEDEKQLIESVKIAYPSLLDAINLLD..KT..HS.IALNDPSFADHCTTIREM...LEGMVRGIVLAKR.....KVSPEVFA.N.ELRFY...............YDAIKVDyNNKYMGPGAVEMP-MFLIDHLLWSC.D...C.....D...D..QV...YTEFKKGYLSYNLPVVREIYDRYENKPSLAARMAQAL.A.T..N.SS.....--..----LEV------FN.NA.LALADLFTVLKSFRMPHKKVAESAYQHQdd.khhQKGSGGYATDILQHIIDL.Q.Q.R.NTAAM.M-----------------salvverqkyvme....................................................................
B8KV85_9GAMM/6-393 ..................................................m-TNTERLDNWIRSDFVALNTALEEIYFS.SEMP.EEV.E...G..K..GDELKRQLEKEGKSFIVDLLKE...GNTN...EGFD.AGFSLLGNVGLYMAACRRH..MITEP..SRETKSPLVEA.S..ALAMQLGASLGVVPRFASAHLENHNYAINGVAKSFTSLPDEILFLTHNTRAELAFIRASEALL..RI..LP.LGVSHPITADLLLVARRA...LEDVLTSNNELFT.....QLDTDRFF.Y.CVRPY...............YKPHRVG.LHEYRGANAGDFAGINVIDLLLGVC.R...A.....D...D..SY...YSQLLVDKFLFMTPDDQLILRDCMSRESLLDQFLRES.I.T..N.HT....eSW..YQKNVALFLDVAKAH.GA.TALQHHEQLVSKFIEKPADNMGLSEKPG......LTASGPPLPVLLRSLRKL.A.D.L.RSAAD.RDDIPSRFSDMQKLRASL.................................................................................
A0A2N1DCJ9_9ALTE/5-391 ..................................................t-PKTQAFDSWIRSDFVKLNDELEALYFQ.QEDK.SNV.E...G..I..GEDIKQSLEREGRDLIKELLAE...GNTD...QGFD.SAFDLLGNVGLYMAACRRH..EITEP..SRETTSPLIEA.S..ALAMHIGASIGVTPRFATAHLTTHNSAQNGIYKRFTSLDDEKLFLDYNTRGILAYKRAADALL..KI..QP.LGISHPISHDLLVSCQKA...LQEVIDSNAILFE.....RLDATRFF.Y.CVRPY...............YKPYRVG.SQVFRGANAGDFAGINVIDLLLGLC.P...A.....N...D..SN...YSQLLVDKFLYMMPEDQTLLRDCMRRESLMNDFLNAK.N.C..A.NQ.....DW..YQDNLGQFLTACQLH.GE.TANQHHEQLVNKYITQPASDLTQTHLNS......VTASGPPLASLLSGLEKL.K.D.K.RMANE.RSDILTRFNDIKTLKASL.................................................................................
A0A6G9H1S2_9ACTN/12-357 ............rtisdldplefvrhvdhltelnahadraglerladdmla----------------------------.----.---.-...-..-..--------------------RV...WNNV...SDLP.TAGAALRDLGFVLASLERH..G----..VDHRTISGAEE.T..LLKL--GDITDEIPRDSVYTYALRNPRS--GTRFFTGIPEEILFIDQVRIAGTALRPAVDDLV..AT..LT.LPLRDPELTERLARAVAG...FRTFAEALLAVKR.....QVTPEVFS.H.RMRPY...............FPPMTVG.GTVLYAPGGAQMTPLL-VDIALLRP.E...P.....G...E..PEagwYPRYLDENLPYLPAAYREAADAIQRHRPLLPRLLDEA.A.R..A.GS.....AL..RDAGR-------EEP.GL.RQLRLLMREVLRFRLPHLQLARANMAIRv...pgSLGSGGYTTSSLDQLAEL.T.T.R.RH---.------------------hqltdalsd........................................................................
K7AL66_9ALTE/5-391 ..................................................t-PKTQAFDSWIRSQFVQLNDELEGLYFQ.QEDK.SNV.Q...G..I..GDDTKQTLEREGRDLIIELLAE...GNTD...QGFD.SAFDLLGNVGLYMAACRRH..EITEP..SRETTSPLVEA.S..ALAMHIGASIGVTPRFATAHLTTHNSAQNGTYKRFTSLQDEKLFLDYNTRGILAYKRAAEALL..KI..QP.LGISHPICHDLLVSCQKA...LQEVIDSNAILFE.....RLDATRFF.Y.CVRPY...............YKPYRVG.SQVFRGANAGDFAGINVIDMQLGLC.L...A.....N...D..PD...YSQLLVDKFLYMMPEDQTLLRDCMRRESLMNKFLEAE.N.H..S.DQ.....DW..YQANVSQFFKACTLH.GE.TANQHHEQLVNKYITQPASQLTQTHLST......VTASGPPLASLLSGLEKL.K.D.K.RMANE.RSDILTRFDDLKILKASL.................................................................................
A0A2Z6UBV8_GLASK/2-389 .................................................ti--NSRAFDDWIRTRFCDLNSELEALYWQ.QDDK.ANV.L...G..I..GDDIKHTLKEEGRQLIVPLLDE...GNTD...NGFD.NAFDLLGNVGLYMAACRRH..EITEP..SQEVSSPLIEA.S..ALAMHIGASIGVTPRFATAHLTTHNKAINGRYKCFTHLEDEAIFIDYNTKGILAYKRAADAII..KI..QA.IGISHPITADLLSAAKHG...LKDVIESNKLLFA.....KLDTDRFF.N.CVRPY...............YKPYRVG.KEVYRGANAGDFAGINVLDLQLGLC.F...A.....N...E..PA...YSQMLVDKFLYMMPEDQDMLRECMRRKSLMDEFLETTpD.M..H.AS.....NW..YQKNTSLFLEVCKLH.GT.TAIQHHNQLVERYIAKPSANIAQQHLDK......ITASGPPLSVLLEELEKL.R.D.R.RAAHQ.RDDIRTRFDDIKQLKSR-l................................................................................
A0A0Q0KGE5_9GAMM/2-388 ...................................................TENTKAFDSWLRTRFVEINSELEKLYWQ.QDDK.ANV.E...G..V..GEHLKRQLEQEGNEHIRALLAE...GNTD...EGFD.NAFDLLGNVGLYMAACRRH..EITEP..SRETSSPLVEA.S..ALAMHIGASIGVTPRFATAHLTTHNKAVDGLYKRFTDLEDEKIFIDYNTKGILAYKRAADALL..KI..QP.LGISHPIAADLLAVAKQA...LLDVIESNNTLYN.....KLDTDRFF.Y.CVRPY...............YKPYRVG.KEVYRGANAGDFAGINVIDLLLGLC.F...A.....N...E..PS...YSQMLVDKFLYMMPEDQQILRESMRMTSIMDDFLAAE.A.E..R.DS.....EW..LQTNLKLFIQVCKLH.GD.TAIGHHNQLVSKYIAQPSQQMQQQHMDK......VTASGPPLHVLLNSLEQL.R.D.R.RAAAK.RDDIRTRFDDLTKLKQW-i................................................................................
A0A1M5E317_9ALTE/3-386 ................................................tpl---VNDFDHWIRTRFVDINTELEHRYFA.QQRR.EEV.S...H..V..GDDLKTSLLEESGEFIRLLLGE...GNTD...EGFD.SGFDLLGNVGFVLAACRRH..EI---..-DEHHSTLKNA.S..ALAMQLGASLGVVPRFASAHLETHNRAINGKYKTFTHLEDEKTFLDYNTRGVFGFVRASEALL..HT..LP.LGISHPVTLDLLNVARVA...LQQVVENNTALFN.....ELDVDRFF.Y.NVRPY...............YKTHKVG.RHEYRGANAGDFAGINVIDLLLGLC.R...G.....D...D..PY...YSQLLVDKFLFMRPEEQLILRDCMRRTSLMDAFLNAT.E.E..E.RN....aSW..FKPHLQAFLAVCEAH.GE.TARQHHEQLISRFIESPAAKYELTKRQD......MTASGPPLEILLAALQKL.H.D.L.RTAAP.RDDIPTRYNDVQTLKGF-l................................................................................
A0A2T0GWJ9_ACTMO/14-362 .............................................qleatr------SADPLGAD--EVCSRLPEM---.-NAE.ADL.A...A..L..TGALRDLLPGFERV------AE...----...LSTD.ECLAAVRDLGMLLGSIKRH..G-SEP..AV--LVPEVLP.V..LLEL--GRRTDMVPRDTVLHYCVWNPEG-TRRRMYTGDPQECTLQNAVRHVFPHLHEGLRLCA..EL..NR.TSPEDERFAQLATRIDGN...VHTMLESIDTVLA.....EVSPVFFA.R.TLRPY...............FEEISLG.GQNYLGPAAAQVP-LWLVDEVVWLS.D...R.....G...I..AE...YEKFLLDSVPYGLPLWRELHAGWRHSPSAVTRLLESF.E.R..A.GG.....-Y..DRAGERL------RD.SA.AALAGVLRTAVTFRGRHYRIARQAYQEEvr..lyPLGSGGGSIDLLHRVLLL.T.-.-.-----.------------------rqnsriaeertkr....................................................................
A0A261GI73_9GAMM/42-355 ...............................kkgnslalssvqtqyisqit----------------------------.----.---.-...-..-..----------------------...----...----.-AHAMTRDLCFLASSLLRH..G----..ASLDEIPGLEQ.F..LLSI--SKITQEIPRDNVYSYSIRNPSG-KRRRSFTGMDEELLFIELLSTSIEDLLKLLCLFP..VA..EA.FDPESQECADLLLRCAGC...LQILTSSIVTVKR.....KISPETFS.Y.ILRPY...............FEPLKIG.GRLWAGHSAAQLP-LLLIDWAMWGV.D...C.....P...D..AD...YHRYFEHNIEYS----PIVIRDYRRLQGLAESYVSVT.E.R..A.LK.....--..-ERNP------CKVEaVA.IALLEILKVLVKFRYPHIKVAEENFSIRe...rnSKGSGGYDMEILHRLAEH.T.-.-.--QHN.RMRIKTALG---------nirvcs...........................................................................
A0A1M5XZR4_9GAMM/2-388 ..................................................s-HHVADFDHWIRNDFIRLNAELEALYYA.QPDR.AEV.E...G..V..GGELKRELEQRGRGFSEALLAE...GNTD...EGFD.AAFDLLGNVGLYLAACRRH..GLSDP..DRDRCSPQAEA.S..ALAMHIAASIGVVPRFATAHLCTHNRAIDGRYKSFTELPDELCFIDYNSKGILAFKRAAEALM..KT..QS.LGISHPITADLLAAAEQA...LLEVQASNQELFQ.....RLDPARFF.Y.SVRPY...............YKPHHVG.SQVYRGANAGDFAGINVIDMLLGLC.Q...G.....N...D..PA...YGRMLVEKFLYMMPDDQRILRDCMRRRSLMDDFLAAR.D.Q..H.RS.....SW..YQTNLAAFLRLCDLH.GA.IAGQHHDQLVHQFIVRPSEQMADKHMEQ......LTASGPQLAHLLKALTDL.R.D.R.RSAAP.REDILTRHREVALLRQLL.................................................................................
A0A2S6GC38_9PSEU/5-372 .................................................sr--TIAALDRWLDDEFTAANTAAEEIYFA.AR-R.DYL.P...G..R..APDL----LHAGARLIAPIAAA...-DLP...EDPM.DQYRLLGSVGLYLAACRRH..RLDDQ..P----AILAPV.W..DLATRLGTALGVAPRYVFAHQVLY------GYRTFTSLPDEDVFVTYNGAAVVAQQRAADALR..RI..ST.MGVSSPLAGELFEQAAAA...LGDALDACRALAD.....RLDVERFY.L.CIRPY...............FATYRVG.DSDFRGANAGDFAAVNEIDLRLGLC.H...A.....D...D..PF...YGRVLREKESYMPPGDRQATHCAARSVPLPTRLLEEP.I.T..R.RT.....--..-RVNARLLLDVCRAH.GA.AASFHHNRLVRPFLARPAATMPTAEPDR......VTASGPPLEVVLADLARL.R.D.L.RVAHT.RLGAAGASAVLDRLR---ama..............................................................................
A0A1Q5LXD5_9ACTN/24-369 .......................................irdadplgadal------------------LAALPAM---.-NRD.ADV.A...A..L..TVALRTLVPDLDRV--------...--SE...WCVI.EALAAMRDLGMLLGSLKRH..G-VQP..VA--AVPEVLP.V..LEEL--ARRTDMVPRDTVHHYTTWNPL-GPRQRMYTGHEMEAHLQEAVRMVFPSLVAALDTCG..QL..AR.LEPYDPGFALALDRTAQH...VQAMVDAIDFTIA.....NVSPSYFA.R.TLRPY...............FEEVDVA.GRDYLGPAAAQVP-LWLVDLTVWQC.D...R.....P...H..PG...YDAFLDESVEYSLPAWRDFHATHKGGVSAVSKLSAAL.S.W..E.TV.....--..HQLPPQL------LA.SA.HSLARVLRILKTFRARHIGIARKAYSDEvr..lyDEGSGGAPVALLRSVLDL.T.-.-.-----.------------------rdnetlvrqaterpr..................................................................
A0A7W7C6V9_9PSEU/2-376 .................................................st--AADRLDHWIRTRFADLNTELEQRYFA.AHTE.ILL.G...D.pE..IDRVKHTIVTQGAALIAEL---...----...-DPV.TSYDLLGLVGFYLGACRRH..EVGSP..AE-----LTPA.Y..AVANRIGLALGVAPRYVFAHQSLYNLAGREGYRTFTTLPDERIFIEYNGLAVLAYQRAATALR..RI..PT.LGVGNPLAGYLLEDARTA...LLDVLRFNQSLAK.....ELDVDRFF.L.NIRPY...............FKSYRVN.GIEYRGANAGDFAAVNEIDLLLGLC.R...Q.....E...D..PF...YQRVLSEKAPYLPPEDQPPLRAAMTTEPLLTAFLRES.A.E..P.MP.....PQ..LRANAELFLEVCRAH.AA.AYAFHHHRLVKPFLEVPAQHAPPSRQED......LTASGPPLSVVIESLARL.A.D.L.RAARD.RPGLTTARAALDQLRD--rc...............................................................................
A0A7K2L0H5_9ACTN/23-358 ....................llaavpamnadadvaaltvalralvpdpdra----------------------------.----.---.-...-..-..----------------------...--AQ...WSVG.HALAAMRDLGILLGSLKRH..G-VQP..LA--AVPEALP.V..-LEL-LGRRTDMIPRDTVHHYTTWNPPG-PRRRTYTGHPTEARLQDAVRMVFPGLVAALDDCG..RV..AR.LEPYDPGFATALDRVARH...VRAMVDAIDLTVA.....QVPPEFFA.T.VLRPY...............YEEVEID.GRDYLGPAAAQVP-LWLVDLTLWQC.D...R.....S...D..PA...YQAFLTESVPYALPAWRAFHARHRGGVSAVSKLSAAV.S.W..E.GA.....DR..LPPSLTA--------.SA.EALGRVLRLLKTFRARHLGIARKAYHEEtr..lyEEGSGGAPVALLRSILDL.T.R.EnETMVR.RA----------------tvrrsp...........................................................................
A0A7J7ZHX8_PIPKU/192-403 ..........................................rdrdtlqka----------------------------.----.---.-...-..-..----------------------...----...----.-------------------..-----..-----------.-..---------------------------------------------------------------..--..--.-----------LGDITSC...LQGALEVFHQINK.....YVDPKLFF.N.VLRIYlsgwkgnaklpegllYEGVWDT.PKMFAGGSAAQSSIFQCFDVLLGIQ.H..sS.....D...E..AS...SAEFLQEMRTYMPPAHRQFLHSLESKPSVRDFVLSEK.D.D..D.LQ.....KI..YNECVHAMVSLR---.--.---QYHLSIVTKYIVIPANESKKKQSSEep..seEVNKGTGGTDVMKFLKSV.K.N.-.-----.------------------tttaallkei.......................................................................
A0A6C7E6K0_ILUCY/11-397 .................................................tp--RVAAFDDWIRNRFIDLNSELEDLYEA.QENR.SQV.A...G..V..GDDLKQVLVDEGRELIVDLLEE...GNTD...EGFD.RAFELLGNVGYYMAACRRH..DITEP..SRERTSPLAEA.S..ALAMHLGASLGTVPRFVSSHMETYNRSINGRYRTFTWRPAEKIFLDYNTRSALAYMRAADALG..RI..HP.MGLSHPAANDLLVDARNA...LDDVLRLNTELAD.....RLDVDEFF.F.CVRPY...............YKPYRVG.SQEYRGANAGDFAAFNQVDMLLGLC.L...P.....T...E..AQ...YTQIVIEKIPYLTPDEQRRLHDSFRHPNLLDSLLEQR.E.H..A.GE.....AW..FRENAQAYLEVCAAH.GA.AAAHHHDELVARFITAPSTGIPPEFLEG......ITASGPPLDVLLRALEGL.R.D.R.RLAAP.RDDIPTRHDDLVELRSL-i................................................................................
A0A7W0HVV1_9ACTN/95-412 ..........................disslvrvfarslpsaeavagfspa----------------------------.----.---.-...-..-..----------------------...----...----.ECLAAMRDLGMYIGSLKRH..G-LSP..FE--IVPRAAG.V..CESL--GRRTGMIPRDTVYHYTCWNPV-GERERLYTGHAMERCLVDAVRTCIPDLARAVDLGH..AL..RG.DDPCGAAYAGRVLSLASY...VSSADRAMGDVAA.....EVAPEFFA.L.VLRPY...............FEDVHIS.GRRYMGPAAAHVP-LFLIDTLLWSS.D...R.....C...A..PQ...YGQFCDEAAAHTLPHWRQWFSEWSRVPSVTSRVARAL.G.G..S.CA.....PA..DMEHVYA--------.SA.QGLRQALRSLTRFRGKHLVMARRAYHEEvr..lyELGSGGGSVGLLAEILTL.T.R.-.QNAA-.------------------mvgal............................................................................
A0A8A8DIL7_9BURK/1-344 ..................................................m-----AACDPLQAR--AFVLQLPGL---.-NRQ.RDV.P...G..I..VGLLRAFLPARGMP--------...--AG...WGFV.EAAAAMRDIGFFLGSLKRH..G-HEP..VD--AVPGLEP.V..LLDL--ARATGLPPRETLLHVTVWNPAAADAQRSYTGLRDEAHLLESVRLSMAALEAAIALTV..EL..SD.VPLQAPAFAQGCDALAAY...LRKMVDSIVYAYR.....FISLQVFY.D.ELRPF...............YEPIRVG.GRSYLGPGAVEMP-LFVLEHVLWGS.Q...S.....D...H..HA...YREFKETYLPYVLPAFRAIYARFAGQPSLVDRALGDA.Q.A..A.RA.....--..RGEPVAA--------.GL.AALDRVFEVLLHFRAPHVKLAERAYEAGks..gpSIGSGGYAPSMLGDLLTL.T.-.-.RAARS.R-----------------vraaldes.........................................................................
A0A1V9G2Q7_9BACT/43-323 ........lnnlpiindkivagggcvyeiiqqvnkplrtlvdtyqsrtltr----------------------------.----.---.-...-..-..----------------------...----...---D.VAIDILRCVAPVISSIQRH..LVTYN.yKQEHFSNLLEC.NieNFLLDLGRVSGLPPRDSV--YTTWLLNDNPVYR-FDTNAGWLFFWKAVRLTNSNFLEANKAID..TIicQN.WAITSGSALDAIAYATEK...VNEVFTFYQGFVK....gGMETDYFA.N.VFRTY...............FLSYRIG.DKQYIGSNATNVASVPALDFKIGVY.-...-.....-...N..EK...YKAIVENRFIQLAHEDIMYIKTAMKEPSLLQLLIEYL.-.-..-.--.....--..---------------.--.----------------------------......------------------.-.-.-.-----.------------------gfdyyefvyfside...................................................................
A0A495XFN4_9PSEU/2-349 ................................................avm----TEFERWLDEGFVRLNTVFEEAYFA.AG-Q.EHV.P...G..L..GQ---EELLHEGAK--------...--RL...PGFDgDPYRLLGSVGMYLAACARH..QVED-..E----EVLAPA.W..ALATRLGTSLGVAPRYVFAHQSLHG------FRTFTSLPDEQVFVRQNGVAVVAYERAAHALR..LV..AT.MGVGGPVVEGLLREARRA...LEEVLAANRTLAD.....TVHPRRFY.L.GIRPY...............FRPHRVG.SQVYRGVNAGDFAAVNEIDLLLGLC.R...A.....D...D..PF...YQRVVAEKMPFVPPDHQDRLKRAVVAEPLLPQVLEEP.R.-..-.--.....--..---HAGLFLEVCRAH.GA.AYALHHGRLVKPFLEAQA-----GDEQD......VTASGPPLSVVVAELGHL.V.D.L.RTGRA.RAGAFGAHEELRRL----aelv.............................................................................
A0A5C9A7C7_9GAMM/2-388 ..................................................t-PNAATFDQWIRGPFRDINSELEALYFA.QPNR.ANV.A...G..V..GDALKQVLLAEGREHIAALLAE...GNTD...EGFD.ANFDLLGNVGFYMAACRRH..ELTEP..SRETRSPLTEA.S..ALAMQLGASLGTVPRFASAHLETHNRAVNGVFKSFTDLEDEITFIAYNTRGAFGYIRAAEALL..HL..LP.LGISHPVAADLLRQAKAS...LEDVHRYNGELFE.....ALDVERFF.Y.CVRPY...............YKPHRVG.LREYRGANAGDFAGINVIDLLLGLC.R...A.....D...D..PY...YSQILVDKFLFMRPDDQLVLRDCMRRRSLLDAFLDEQ.G.S..S.ES.....PW..YRHNLQLFLEVCEAH.GR.TALQHHEQLVEKFIVKPADEGDLVEDKG......LTASGPPLPVLLKALKTL.C.D.L.RAGAE.RDDIPSRYRELATLRSL-l................................................................................
A0A2R4T8D7_9ACTN/34-375 ......aadplgadamlaalpamnaaadvpaltvalralvpdpdrvaalsv----------------------------.----.---.-...-..-..----------------------...----...---V.DALAAMRDLGILLGSLKRH..G-TEP..VP--AVPEVLP.V..LEEL--GRRTDMVPRDTVHHYTTWNPLG-ARQRMYTGDRMEASLQDAVRMVFPSLVAALGTCA..EL..AR.LEPYDPGFALCLDRTAQH...VQAMVDSIDFTVA.....NVSPVFFA.Q.EMRSY...............FEEIDVA.GHEYLGPAAAQVP-LWLVDLTLWQC.D...R.....S...N..PK...YDAFLRESVQYSLPSWRDHYARHQGGTSAVSKLSAAI.S.W..E.AV.....DR..LPQQLAA--------.SA.VSLARVLRILKTFRARHMTIARKAYSEDvr..lyDMGSGGAPIELLRSVLDL.TrD.N.E----.------------------tlvrrsver........................................................................
L5LS41_MYODS/187-399 ............................................nqdrdtl----------------------------.----.---.-...-..-..----------------------...----...----.-------------------..-----..-----------.-..---------------------------------------------------------------..--..--.--------QKALRDITSC...LKKALEVFHQIHE.....YVDPDLFF.N.VLRIYlsgwkgnakmpegllYEGFWDT.PKMFAGGSAAQSSIFQCFDVLLGIQ.H..sS.....D...E..AS...SAEFLQEMRTYMPPAHQKFLHSLESKPSVREFVLSEG.D.D..S.LL.....AI..YNECVDAMVSLR---.--.---NYHLQIVAKYIVIPAKQSKNTQPSEep..seSENKGTGGTDVMKFLKSV.R.D.T.TKAA-.------------------llkei............................................................................
A0A1E5PIT5_9ACTN/13-362 ...........qadplaadpllavlpamnrdadvpaltvalrtllplpaaa----------------------------.----.---.-...-..-..----------------------...--DE...WSVV.ESLAAMRDLGMFLGSLKRH..G-TEP..LD--AVPEALP.V..LETL--GRRTDMVPRDTVHHYTTWNPI-GLRRRTYTGEAMEADLQDAVRMVFPSLAASLDTCA..AL..AR.LEPHDPGFAVSLDRTAQH...VQSMVDSIDFTVA.....NVSPVFFA.R.TLRPY...............FEEIDVA.GRDYLGPAAAQVP-LWLIDLTLWQC.D...H.....S...S..PE...YDEFLAESVPYSLPSWRDFHAAHTGGASAVSKLAAAV.D.W..E.NA.....DR..LSPQLAA--------.SA.VSLARVLRILKTFRARHIGIARKAYSDDlr..lyEVGSGGAPIELLRSVLDLtR.D.N.ETLVR.RATGRSRT----------pvash............................................................................
A1SB64_SHEAM/5-391 ..................................................t-LNVEAFDDWLRTRFVELNNELEHLYWL.QTDK.ANV.T...G..V..GDDLKAQLETEGRKHICALLDE...GNTD...EGFD.AAFDLLGNVGLYMAACRRH..EITEP..TRETQSPLVEA.S..ALAMHIGASIGVTPRFATAHLTTHNLARDGKYKRFTDLPDERLFVDYNTKGILAYKRAADALL..KI..LP.LGVSHPITADLLKVARQA...LQDVMDSNTTLFN.....ELDTDRFF.Y.CVRPY...............YKPYRVG.SQVYRGANAGDFAGINVIDLLLGLC.Y...A.....N...E..PS...YSQMLVDKFLYMMPEDQAILRDCMRRSSLMEHFLAAT.G.A..K.EQ.....SW..YQDNLSLFLEVCELH.GQ.TAIQHHDQLVHKYIAEPSVNMQQQHMSK......VTASGPPLHVLIGALEKL.R.D.R.RAAAK.RSDIRTAWQDVARLKATL.................................................................................
A0A0F4NW72_PSEO7/3-388 ................................................pla----VQFDAWIRGPFVDLNDKLEHLYWQ.QQDK.ANV.E...G..V..GETLKAQLLEEGNQLIQALLEE...GNTD...EGFE.QAFDLLGNVGLFMAACRRH..EITEP..SRERVSPLTQA.S..ALAMHIGASLGVTPRFATAHLTTHNRAINGVYKRFTSHPAERLFIDYNTQAILAYKRASESLM..KV..HH.LGISHPMSLVLLKQVKQA...LLEVIESNRELFK.....ELDTEAFF.Y.VVRPY...............YKPYRVG.KEVYRGANAGDFAGINVIDMMLGLC.P...A.....N...D..IS...YGQMLVEKFLYMMPEDQATLRECMRTPNLMDAFLSAL.K.G..P.KS.....DW..FGPACSLFIQVCKLH.GD.TAIQHHNQLVEKYIAKPSQAMQQQHLSK......VTASGPPIEVLLKELADL.R.D.R.RAAAE.RADIFTRHHDLKRLRQA-i................................................................................
A0A1G8W512_9GAMM/2-389 ...................................................TQHAQAFDQWIRTDFKAINTELEQLYFQ.QQDK.ANV.E...G..V..GDDLKARMESGGRGFIEKLLAE...GNTD...EGFD.SNFDLLGNVGMYMAACRRH..DLTEP..SRERKSPLKAA.S..ALALHIGASLGVTPRFATSHLTTHCLAKAGVPKRFTSLDDEALFIDYNTLAVLAYKRAADALV..RI..LP.MGISHPVAIHLLEDARQA...LVDVAKWNQVLFD.....KLDSERFF.N.SVRPY...............YKPFRVG.QHEYRGANAGDFAGINEIDMLLGLC.Q...A.....N...N..PF...YSQLLVDKFLYMMPEDQRRLRDVMRRRSFLDDLLSAA.K.T..D.AD....sDW..FQRVLPAFLAVQQAH.GH.TAIQHHDQLVSRFIAKPSTEMAAQHLKQ......VTASGPPLEVLMRSLQGL.R.D.L.RAAAP.RDDIPSRYRDINALSA--lv...............................................................................
J0U836_9BURK/3-389 .................................................ia--SATAFDGWIRSRFKDFNTELEELYFA.KADR.ADV.E...G..T..GDGTKAALRDEGAGHIARIHAE...PRLY...EDEA.RSYDLLGNIGLYMAALRRH..ELTNP..DREERSPFPVA.S..ALAQRLAAGLGVAPRFATAHVNLRNLAIGGEHKSFTRLPDELLFIEYNCLPILAYIRAADVLR..RI..AP.LGVAHPASLALLRDAQAA...LKDVGRYNAELHR.....RLDVDRFF.Y.NIRPY...............FKTYRVG.RHAYRGANAGDFAAINEIDLCLGLC.R...V.....S...D..PG...YAGIVMEKMPFLPREDQQALQAACWQQSLLDAFLEAA.P.A..A.HG....hAG..LRANVQAFLDVCAAH.GE.TAAQHHELFVHRFIEVPSTRMEEKHLAQ......ITASGPPLQALLAALEAL.R.D.R.RLAVD.RPGIDSRHADLAVLRA--l................................................................................
A0A6N0X3I6_9SPHN/1-388 ..................................................m-DNAEKFEGWIRGPFVEMNTELEDLYFA.QPDR.MEI.E...S..V..GTSIKETLRDEGRALIVPLLEE...GKTG...DGFV.NAFGVLGNVGLYLGALRRH..EMTNP..DREERSPFVEA.S..ALALHIGVSIGMVPRFATSHLATHNLAVNGIRKSFTSLRDEFLFIDENTRGILSFQSAADALT..RI..VP.LGVTSPVADVLYEQAKQA...MANVIRFNDRLFT.....ELDIDRFF.F.SVRPY...............YKPYRVG.RQIYRGANAGDFAGINEIDLMLGVC.R...A.....S...D..PS...YSQLLHEKMPFMLPSEQRRLNECMSRRSLLDELLLLIdD.H..A.DK.....PW..FRSSARMYLEVFDLY.AE.TARQHHDQLVMRFIQRPSDNLAQARLTG......ITASGPSLEVLIRSLETL.R.D.Y.RCAAD.RPDLATRHRDIARLRAV-a................................................................................
A0A1I1M8M0_9BACT/29-382 ........................................yvstldplgid----------------QAIKELPTL---.-NKN.KDV.E...G..I..VALLRRYLPTPDLV--------...--NF...FDFP.EMLACMRDIGLFLGSLKRH..G-VEP..VE--KVPELEP.V..LGIL--GEKTNMPPRDTLFHYTIWNPSGDR-LRTYTGTPDEIALIQSVQMAMRPLIESIHHLE..EM..HE.SDPLDAQFAEIGQAASEA...FTGVISGIVQAKR.....YVSPHYFA.Q.ELRLY...............YDPIIWK.GDSYYGPGAVEMP-MFLFDHLLWSS.E...I.....T...D..SK...YVEFKKAYLAFNQPFVRELYDRFEGKPSLLQKTISAL.E.T..T.KDnrdsqEYlcAKNSAKMLLGVCNML.KS.FRMPHKKIAEESYKSQHAGQSQPPQEAQ.....rSHGSGGYTIDILSHVLAL.N.-.-.-----.------------------vasidaleea.......................................................................
S9PK82_9DELT/1-237 .................................................mc----------------------------.----.---.-...-..-..----------------------...----...----.------------LGSLEHH..G-YEP..LE--RVPQLEP.V..LRRL--GERTGLPPRDTLLHYSVWNPPGDR-LRTYPGLPDEEQLIQSVRLAIPPLESAITRLA..EL..HE.VPVRAPDFVPLCTQVLEG...LRQLVESIAHAHR.....HVSPHVFA.T.ELRSY...............YDPILIG.GTPYLGPGAVEMP-LFVLEHLPWGS.S...S.....K...E..AR...YLAFKERYVPYILPELRALYRRHVGRPSLVDRVLEEV.H.A..L.EE.....--..---------------.--.----------------------------......------------------.-.-.-.-----.------------------pddaaragvdtlrwqtsalgvnqalp.......................................................
Q1YT13_9GAMM/2-390 ...................................................TDKAKALDLWIRNDFRQINTALEALHFS.QPDR.LPA.P...G..L..GEVLKRRLVEEGTALISDLLNE...GNTD...EGFD.SGFDLLGNVGFYMAACRRH..EITEP..SRETGSPLREA.S..ALAMQLGASLGVIPRFASSHLETHNRAISGVYKTFTDLDDEKLFLDYNTRSVFAFIRASEALR..QI..LP.LGVSHPVTYDLLLSAKQS...LEQVYAYNQTLFE.....KLDVDRFF.Y.CVRPY...............YRPHRVG.LHEYRGANAGDFSGINVIDLLLGLC.R...A.....D...D..PY...YSQLLVDKFLFMRPDDQLVLRDCMRRTSLLDSFLATA.D.T..D.KQ....qPW..VQRNLQLFLQVCHAH.GQ.TALQHHEQLVNKFIERPADKGSLSETSG......ITASGPPLPVLLKSLRKL.C.D.M.RCAADvGGEFKTRHKDIEYLKGL-l................................................................................
A0A652KBU9_9ACTN/23-368 ........................................dicaadplgad----------------ALLAALPAM---.-NAD.ADV.A...A..L..TVALRTLLPDHDRA--------...--AE...WNVV.AALAAMRDLGILLGSLKRH..G-VQP..AE--AVPEVVP.I..-LEL-LGRRTDMVPRDTVHHYTTWNPAGP-RRRTYTGHPMETDLQEAVRMAFPGLVAALDTCA..RV..AC.LEPYDPGFATALDRTAHH...VRSIVDSIDFTAS.....NISPEFFA.L.TLRPY...............FEEVDVA.GRSYLGPAAAQVP-LWLVDLTLWQC.D...R.....S...D..AA...YDAFLAESLPYSLPSWREFHEQYAGGVSAVSKLSAAL.S.W..E.NA.....ER..LPRELAA--------.SA.LALGRVLKILKTFRARHIVIARKAYSDDlr..lyEEGSGGAPVALLRSILDL.T.-.-.-----.------------------rdnetlvrqatsgr...................................................................
A8H9J6_SHEPA/2-388 ..................................................t-GNTQAFDHWIRTRFVELNSKLESLYAQ.QADR.ANV.E...G..V..GEDLKFQLESEGRELIACLLAE...GNTD...EGFD.HAFDLLGNVGLYMAACRRH..EITEP..SRERVSPLTEA.S..ALAMHIGASIGVTPRFATAHLTTHNRAHQGLYKRFTDLDAEQLFVDYNTKGILAYKRAADALL..KI..QP.LGIDHPIAYDLLLVAKRA...LRDVIESNRVLFQ.....RLDADDFF.Y.CVRPY...............YKPYRVG.SQIYRGANAGDFAGINVIDMLLGLC.S...A.....N...E..PG...YSQMLVDKFLYMMPEDQAILRDCMRRTSFMDELLNLS.H.F..S.AE.....PW..YQQNVKLFLEVCALH.GE.TAIQHHNELVAKYIAQPSKTMEQQHMSK......VTASGPPLDVLLNSLEKL.R.D.R.RAAAK.RSDIRTRYEDIQSLLAS-m................................................................................
A0A0F4QE14_9GAMM/2-389 .................................................tt--LTQAFDHWIRSDFVALNDKLETAYWQ.QQDK.ANV.V...G..V..EDDIKQQLLNEGQQHIQALLSE...GNTD...EGFD.NAFDLLGNVGLYMAACRRH..ELTEP..SREQYSPLKEA.S..ALAMHIGASIGVTPRFATAHLTTHNRAINGVYKRFTSHPAEQLFIDYNTRAILAYKRAAECLL..KI..QP.LGISHPMTPVLLMQVKEA...LLDVIRSNQCLFE.....QLDTDAFF.Y.VVRPY...............YKPYRVG.KEVYRGANAGDFAGINVIDMLLGLC.Q...A.....N...D..VN...YAQMLVDKFLYMMPEDQATLRECMRLPNLMDAFLAAA.P.Q..H.HA....sGW..YQEAVSAFVQVCKLH.GD.TAIQHHNQLVEKYIAKPSGDMNTAHLDK......VTASGPPLPVLLNQLALL.R.D.K.RAAAK.RDDVFTRFDDLNTLRRS-i................................................................................
A0A2N5Y1J1_9GAMM/3-390 ................................................tpl---AQAFDTWIRDDFRDMNTRLEELYFS.GEHP.ERV.T...G..V..GDDIKQQLVDEGREYIVQLLQE...GNTD...EGFD.HGFDLLGNVGFYMAACRRH..GITDP..AVEHRSPLTEA.S..ALAMQLGASLGAIPRFASAHLETHNRAINGVYKSFTSLPDERIFLDYNTRGVFAYIRAAEALL..HI..LP.LGISHPVSLDLLRVAKVA...LEDVFDSNRELFQ.....ALDTERFF.Y.CIRPY...............YKPHRVG.LHEYRGANAGDFAGINVIDLLLGLC.R...A.....D...D..PY...YSQLLVDKFLFMRPEDQLVLRDCMRRKSLLASFLEEL.Q.P..H.GQ....tPW..FRRNVAAFLEVCEMH.GQ.VAQQHHQQLVEKFIVAPARDAGLENQQD......LSASGPPLPVLLKGLRTL.C.D.L.RSAAD.RTDIPSRFPDIQRLRNML.................................................................................
A0A2C9ZZH4_PSEDV/2-388 ..................................................t-NHSTLFDDWIRDDFIDLNTELENLYWQ.QSDR.ANV.E...S..I..GQSLKQALEQQGQHFINALLAE...GNTN...QGFD.HAFDLLGNVGLYMAACRRH..EITEP..SRETHSPLIEA.S..TLAMHIGASIGVTPRFATAHLTTHNKAVEGEYKRFTHLPDERVFIDFNTKGILAYKQAADALI..RI..QP.LGISHPATADLLTTAITA...IQTVQKHNQTLFH.....TLDAERFF.Y.CVRPY...............YKPYRVG.SVVYRGANAGDFAGINVIDLLTGLC.A...G.....N...D..KV...YSQMLVDKFLYMMPEDQAILRDCMRRPSMLDLFLQQQ.H.C..A.HH.....LW..FQENLHLFLQLCQVH.GQ.AATQHHDQLVEKFISQPSQSLQAQHLDK......LTASGPALPILIDALEKL.R.D.R.RTAAP.RNDIKTRYHDIKTLSA--li...............................................................................
A0A2P8B2B2_9ACTN/31-373 ...................frlramnaqadvpaisgalralipgldevaty----------------------------.----.---.-...-..-..----------------------...----...-SVD.ECLAAMRDLGMFLGSLKRH..G-VEP..LP--VVPEVTV.V..LEE--IGRRTDMVPRDTVHHYTTWNPV-GHRQRMYTGDPQEGFLQESVRMVFPDLRTGLNTCD..AL..AD.TEPTDPEFAPLLDELNVR...LTSMVDSIDMVLR.....HVSPVFFA.R.VLRPY...............FEEITVE.GRELLGPAAAQVP-LWLVDQVIWAT.D...R.....S...D..PG...YEEFIRHSVPYSLPRWRNYYTRWTERRSVVSRLIDAF.G.G..V.DG.....AL..TGGGSPV-----LRR.GA.EALARVLRTVVVFRGRHLGIARQAYQADlr..lyPVGSGGASVDLLRQIIDL.T.R.-.-QNAN.------------------lvqarrsdpsteerraq................................................................
A0A395JV47_9GAMM/3-390 .................................................tp--NSRHFDHWIRQDFKHINTELELAYRE.AGCK.DSV.T...D..V..GDALKQQLLREGNQHITALLRE...GNTD...EGFD.NGFDLLGNVGFFMAACRRH..DLTEP..SREHKSPLTDA.S..ALAMQLGASLGVIPRFASAHLETHNRAINGEYKSFTNLPDEHLFLEYNTRGVFAFIRASEALL..HC..LP.LGVSHPVTHDLLVAAQHD...LKTVISNNNALFE.....KLDIDQFF.Y.CVRPY...............YKTHRVG.LHEYRGANAGDFAGINVIDLLLGLC.R...A.....D...D..PY...YSQLLVDKFLFMRPDDQLALRDCMRRKSLLDGFLEVD.D.N..A.TQ....dDW..FQRNAEAFLQVCELH.GQ.TALQHHELLIKKFIELPAARDGLEKQSD......LTASGPPLDVMLKGLKKL.C.D.L.RTAAN.VEGLSTRFNDLQKLRSV-v................................................................................
A0A1C6QHX0_9BURK/1-305 .............................................misnll----------------------------.----.---.-...-..-..----------------------...-NAN...WYEA.VALAAMRDVGLVLGSLKRH..G-VEP..LT--VVPQIEP.L..LLQL--GGLCEMVPRDTVLHYTSWNPDG-PRRRAYTCDPQERLLQASIVKVFPSLSASLCVSA..SL..RE.MSPRDARCAPLVDSLHSM...ATSMVESIDGVVQ.....NVSPAFFA.Q.TLRPY...............FEDVKIG.GRAYLGPAAAQVP-LWLMDLCVWAS.D...R.....S...S..EN...YRRFLDESVPYCLPPWRIYYEQFGAAQSLVSRLGQYM.A.D..P.EM.....--..----AQ----DCNLL.GTaSSIARLLKTLKAFRGRHLGIARKAYAPEir..ryEQGSGGAPVSLLKEIIDL.T.-.-.-----.------------------iqsehsvlge.......................................................................
A0A7J7Z3K7_MYOMY/40-255 .........................................avqnqdrdtl----------------------------.----.---.-...-..-..----------------------...----...----.-------------------..-----..-----------.-..---------------------------------------------------------------..--..--.--------QKALLDITSC...LQKALEVFHQIHE.....YVDPDLFF.N.VLRIYlsgwkgnakmpegllYEGFWDT.PKMFAGGSAAQSSIFQCFDVLLGIQ.H..sS.....D...E..AS...SAEFLQEMRTYMPPAHQKFLHSLESKPSVREFVLSEG.D.D..S.LQ.....AI..YNKCVDAMVSLR---.--.---NYHLQIVAKYIVIPARQSKNTQPSEep..seSENKGTGGTDVMKFLKSV.R.D.T.T----.------------------ksallkei.........................................................................
A0A7W7QBW1_9PSEU/1-353 .................................................ms--AVTDFTRWLSTEFTAANTGLEGAYFA.AGQE.IVY.D...D..H.dLDQRKRALRDDGATLVTRI---...GTTS...T--D.NPYDLLGAVGLYLAACRRH..EVDAP..EA--------A.Q..AVAGRLGLALGVAPRFVFAHLSTHNPAA----RTFTDLPDEQLFIDHNGLGVLAYQRAAAALR..RI..PS.--VTTALAAALYDEALAA...LDAVLAANRALAE.....SLDPDRFF.L.NVRPY...............FKPHVVV.GTEYRGANAGDFAAVNEIDLALGLC.D...L.....G...D..PF...YQRILAEKYPYVPPEDQPRLRTPP------ADLLALV.E.R..D.GT.....--..---HAERYLAVCRAH.GA.AYAFHHHRLVVPFLARPAESMPPDRRAR......LTASGPPLDVVLATLSRL.V.D.L.RAARD.RP----------------gtaservravt......................................................................
A0A1S2KG16_9ACTN/46-375 ...........................mnhaadvpaltvalralvpeparl----------------------------.----.---.-...-..-..----------------------...--AR...WGVV.ECLAAMRDLGLLLGSLKRH..G-TEP..VA--AVPEVGP.V..LREL--GRRTDMVPRDTVHHYTTWNPLG-ARRRSYTATDMERHLQDAVRMVFPSLVAALDSCA..DV..AR.LEPYDPGFAPALDRTAQH...VQSVVDSIDFTVA.....NVTPEFFA.R.VLRPY...............FEEIDVD.GRDYLGPAAAQVP-LWLVDLTLWQS.D...R.....S...D..PA...YDAFLDESLPYSLPAWRAFHAAHRGSVSAVGKVSAAL.S.W..E.SA.....HR..LPPQLT--------A.SA.LSLARVLRLLKTFRARHIGIARKAYHDDlr..lyDNGSGGAPVALLRTVLDL.T.-.-.-----.------------------rdnetlvrralphadvs................................................................
A0A0K1JDM7_9MICO/66-364 .................................................vq----------------------------.----.---.-...-..-..----------------------...----...----.-GLAVMRDLGIVLGSIKRH..G-TEP..LD--VVPELTP.L..LLAL--GRQTDLVPRDTVQHYTSWNPPGA-RRRTYTDDEQETWLQDSVSHVFPDLSASLSISE..TL..VD.LDPRDTRFAANARLLART...VHSMLEAIDSVTA.....RVSPIFFA.Q.EMRPY...............FEEITVD.GTEYLGPAAAQVP-LWLVDLCLWAS.D...R.....N...A..DA...YGSFLSESLQYALPDWRDFHGRHHHRPSLVTRLSNLM.M.A..D.PR.....--..-RTSPAL------IE.SA.KAVGDLLRTLKTFRGRHITIAKKAYAEDvr..lyENGSGGAPIALLQEILDL.T.-.-.R----.------------------enenlirsrhrpapr..................................................................
A0A1H3MGE0_9BACL/52-345 ..........................................ihkvafyap----------------------------.----.---.-...-..-..----------------------...----...--FE.VRIRSMGDLGIYLVSCLRA..GI--P..ME-KLSPIYES.-..-LCM-LSPTTGVVPRDTYCSYATHNS--EEAMRTFTGHESEIGFIRQHQRSDEALMPAVDHLL..QL..QT.VN-EQGNYGESLTMIRDC...VKKLIDENKNVHQ.....AVDPVFFI.K.YFREY...............FFPIEIQ.GKMLNAPSGVHLA--NIILLDIGIG.S...A.....D...D..-R...YLDTTDELMIYLEPIERLKIIQTKSFPSLREKFIKEY.K.T..N.GT.....--..NREELNLLMDIYKYM.R-.IYRYVHQGLVTRYIRKQDT---------......------------------.-.-.-.-----.------------------nvkfgtggfpfdefleeriqivkraeedvrka.................................................
A0A2K8KNV6_9GAMM/18-404 ...................................................TAKTELFDDWIRTRFVELNSALEDLYFA.QADR.ANV.A...G..I..GEDYKICLEQEGQALIAALLAE...GNTD...QGFD.KAFDLLGNVGLYMAACRRH..EITEP..SRETKSPLLEA.S..ALALQIGASIGVTPRFATAHLTTHNRAVNGRYKRFTNLPDEQLFVDYNTRGILAYKRAADALI..KI..QP.LGISHPLTHDLMSAALVA...LQQVIESNSDLFE.....QLDAQRFF.H.CVRPY...............YKPYRVG.SQIYRGANAGDFAGINVIDLLLGLC.Q...G.....N...D..PT...YGQLLVDKFLFMMPEDQQILRDCMRRTSLLDYFLAAG.D.Q..S.QA.....PW..YQANLSLLLELCQVH.GE.TASQHHNQLVEKYISQPSAQMPEQYLDK......LTASGPPLPVLLAALEKL.R.D.R.RAAAQ.RSDILTRFHDIQQLKATL.................................................................................
B8KTW6_9GAMM/2-388 ..................................................t-GNVENFDRWIRSEFADLNTVLENAYFQ.RSDR.ADV.T...A..V..GAAEKGQLRAAGTAHIVELLRE...GNTD...EGFD.AGFDLLGNVGLFMAACARH..GIADQ..NA-KDGDMPEA.S..GLALQLGASLGVTPRFATSHLTTHNRAIDGRYKSFTTLRDDYLFTDYNTRGILGYKRAADALL..RI..LP.LGITHPVAADLLAAARDA...LKYVVQSNETLFT.....ELDTDRFF.Y.SVRPY...............FKPHRVG.QHSYRGANAGDFAGINVIDMLLGLC.R...A.....D...H..AY...YSQLLVDKFLYMMPEDQSILRDCMRRRSLMDEFLCLP.D.S..AwHD.....TH..CRDNLALFLEVCDLH.GQ.TATQHHNQLVTKFIEQPAVHIDDKHQEN......LTASGPPLEVLMRALARL.R.D.L.RSAAD.RDDIPSRYHDIVKLRAKL.................................................................................
A0A4R2KN42_9GAMM/3-390 ................................................tpl---ASKFDHWIRQDFRDMNTALEELYFA.QENR.DNL.E...G..V..GDGIKQQLVTEGRDYIAQLLRE...GNTD...EGFD.HGFELLGNVGFYMAACRRH..GITDP..ARETRSPLREA.S..ALAMQLGASLGAVPRFASSHLETHNRAVNGVYKTFTALNDERIFIDYNTRGVFGYIRTAEALL..HS..LP.LGVSHPVTLDLLRVARAA...LEDVFASNQELFT.....ALDMQRFF.F.CIRPY...............YKPHRVG.LREYRGANAGDFAGINVIDLLLGLC.R...A.....D...D..PY...YSQLLVDKFLFMRPEDQLLLRDCMRRKSLLNSFLEEA.E.E..HaGE.....DW..FQTNVSAFLEVCEAH.GR.VAVQHHELLVEKYIVQPASDAGLEDKAD......LSASGPPLPVLLKGLKTL.C.D.L.RSAAP.RDDIPSRYRDIGRLKAC-v................................................................................
A0A561UPP3_9ACTN/14-356 ..vaaadplradrllaelpalnaradprplgellaalagaadraplesaae----------------------------.----.---.-...-..-..----------------------...----...----.-RLAAMRDMGMTLGSLKRH..G-VEP..LS--AVPAAGP.V..LRRL--GARAEMVPRDTVLHYGAWNPR-GDRQRMYLGAPEEDVLIQSVRLGAVAVERAALGLA..EL..DG.ADPGTPEYFRVLRQAVRD...FEVLPEQIGVVAG.....KVAPAGFFmA.RLRPY...............FEDVRVG.DRSYYGPAAAHVP-LHLVDQLLWSS.D...R.....V...D..PA...YAELTREMLDYGLPEWSRLHHEREGAESVVTRVVRAL.L.A..A.GQ.....--..-EASPQL-----LLT.GR.TVAELLRSMVV-FRGRHLRLVREAYTVDs...pyTTGSAGGAPELVKRVLEL.T.-.-.-RACE.R-----------------qlvgrade.........................................................................
A0A1C3EKP0_9GAMM/2-389 ...................................................TDNVIAFDSWMRDGFVELNNDLERLYWA.QEDK.ANV.D...E..V..GDDVKKTLVAEGNQLISSLLQE...GNTD...EGFD.AAFDVLGNVGLFMAACRRH..EITEP..SREHVSPLTEA.S..ALAMQIGASIGVTPRFATAHLTTHNKAVAGKYKRFTDLDAERIFVDYNTKGILAYKRAADALL..KI..KS.IGISHPIAADLLRVAHRA...LQDVHESNSILFS.....KLDTDGFF.Y.QVRPY...............YKPHRVG.QNIYRGANAGDFAGINVIDLLLGLC.L...A.....N...E..PS...YSQLLVDKFLYMMPEDQQILRDCMRMTSFMDEFIALS.E.S.cR.HQ.....SW..FQEHLSLFIDVCRMH.GQ.TAQQHHNQLVEKYIAKPANDMVENHLDK......VTASGPPLPVLLGALEKL.R.D.R.RCAAQ.RNDIYTRYEDMQMLEAML.................................................................................
A0A4Q7X553_9ACTN/36-272 ................................twlrtraehlsrhaasird----------------------------.----.---.-...-..-..----------------------...----...--AA.PARAALRDLGMITASLARH..T-GHP..VP---PPAVQA.A..MLRL--GAAADEVPRETVYSYATRNPR-GPRRRSFTDTPGEHVFIDEVTAASHALDDAIRHCS..G-..LP.AAADRNTADALAAVVHER...LRDFAARLLTVKR.....TLTPHYFT.G.LLRPY...............YPPLEID.GRTYYAPGGAQMP-LLVLDVVILSQ.A...A.....TgelA..AW...YEQYVTDNVLYLPPHHRALVDAGRR------------.-.-..-.--.....--..---------------.--.----------------------------......------------------.-.-.-.-----.------------------tpglarlahrr......................................................................
A0A8J4DU23_9ACTN/24-352 ............lsadqacqhlramnhnadvpalanalrvltpgldevety----------------------------.----.---.-...-..-..----------------------...----...-SVD.ECLAAMRDLGMFLGSIKRH..G-TEP..AS--AVPEVVP.V..LREL--GRRTEMVPRDTVHHYTTWNPV-GHRQRMYTGDPQESVLQESVRMVFPALRHGLDLCD..EL..SD.TAPGEDRFAPLLDALTTR...LGAMVDSIDLVLR.....EVSPVFFA.R.VLRAY...............FEEVTLD.GKVLLGPAAAQVP-LWLVDQVIWAS.D...L.....G...S..PD...YEEFIRDSVPYSLPRWRHYYARWEGRPSAVSRLLAAY.G.P..S.GV.....-N..ETPVLR--------R.GA.ESLFRLLRTVVVFRGRHLGIARQAYQADlr..lyPVGSGGASVELLRQIIDL.T.-.-.-----.------------------rqnsg............................................................................
A0A2V4N0T0_9ACTN/16-352 ...........plgadrllallprhneradrralvallaelvaaaeraplt----------------------------.----.---.-...-..-..----------------------...----...-GTA.EQLAAVRDLGLPLGSLRRH..G-VEP..LG--AVPGAEP.L..LRRL--GGSVGMVPRDTVLHYGAWNPTGA-RQRMYTGAAAESVLIHSVRVGAPSAERTALALA..AL..SE.QDPAAPEYADALAEAGAR...LRPLVESVDAVAE.....QVAPAEFF.TaRLRPF...............MQEVRVG.TRAYYGPAAAHLP-LHLVDQLLWAG.D...R.....T...D..PV...HRGLQLDLLEYGLPQWSRLYRERTGRESVVSAVLRAL.R.A..A.GT.....GA..PTTLLRS--------.AQ.AAAALLRQLVV-FRGRHLRLVRAAYTEDg...pfRAGSAGAAPELVRHLLDL.T.R.E.RA---.------------------rqvagahs.........................................................................
A0A7J7Z3J0_MYOMY/193-404 .............................................qdrdtl----------------------------.----.---.-...-..-..----------------------...----...----.-------------------..-----..-----------.-..---------------------------------------------------------------..--..--.--------QKALLDITSC...LQKALEVFHQIHE.....YVDPDLFF.N.VLRIYlsgwkgnakmpegllYEGFWDT.PKMFAGGSAAQSSIFQCFDVLLGIQ.H..sS.....D...E..AS...SAEFLQEMRTYMPPAHQKFLHSLESKPSVREFVLSEG.D.D..S.LQ.....AI..YNKCVDAMVSLR---.--.---NYHLQIVAKYIVIPARQSKNTQPSEep..seSENKGTGGTDVMKFLKSV.R.D.T.T----.------------------ksallkei.........................................................................
A0A2S7K8P1_9PROT/2-389 .................................................sa--NSENFENWIRSGFVEMNTELENLYFA.QERR.ENV.D...G..V..GDKLKAQIRDEGHDFVVRLQAE...GNTD...EGFD.NAFDLLGDLGLYLAALRRH..ELTNP..AREEKSPFPEA.S..ALGLHIAASIGMAPRFATAHLATRNAAKDGLQKSFTTLKDEFLFLDYNTRSIFSFMRAADALT..RI..LP.LGVSHPVAHTLLEDAANA...LKDVIKYNEMLYD.....YLDTDRFF.Y.SVRPY...............YKPYRVG.RHEYRGANAGDFSGINEIDLLLGLC.Q...A.....N...D..PY...YAQLLVDKMLFMTPEDQASLRDCMRRRSLLAQFLDIApG.S..S.HE.....PW..FKRNAAAFLEVCRLH.GQ.TASQHHDRLVTTFIEEPSTALGGDKLAQ......VTASGPPLQVLMRALETL.R.D.M.RLAAN.RTDIKTSYKDIEALKAF-v................................................................................
A0A1S2PD07_9ACTN/38-272 ...................................lhtraerlsrhavsir----------------------------.----.---.-...-..-..----------------------...----...-DVA.PARAALRDLGMITASLARH..T----..SCQVPPPAVET.A..MLHL--GATADEVPRETVYSYTTRNPR-GPRRRSFTDTPGEHVFIDEVTDASHALDDAIRHCA..GM..PE.-AANQEAADGLAATVHER...LRAFAAHLLTVKR.....TLTPEYFT.G.LLRPY...............YPPLDID.GTTYYAPGGAQMP-LLVLDVMILSQ.A...A.....TgnlA..AW...YEQYLTDNVLYLPPHHRAMVDAARRTP----------.-.-..-.--.....--..---------------.--.----------------------------......------------------.-.-.-.-----.------------------glarlarnr........................................................................
G7Z6M6_AZOL4/72-388 ........................sllerevaahidpqiigpivysghvdq----------------------------.----.---.-...-..-..----------------------...----...---E.LALRYLGLLGFAVSSLERHaqGAGRPagSALAAMPGVER.C..LLEL--GRIANHPPRD--SHYTYWLNNNSDDPLTFTGETGEKFFNFAVNQTDLLLGNAADYLLdiRI..GA.LSLRDPQAVLCIEEAAASiaiLRRVYLDYRRPVEggtgaRMTP-LDF.N.RMRNY...............LLPYPVG.GMMHSGPNATNVAAYPRVDLAIGWA.-...-.....-...D..EA...FCATIAQRLSHMNDRDAALVRRDLGLPSLAERLLDLI.G.L..R.TE.....KG..V--------------.--.----------------------------......------------------.-.-.-.-----.------------------sptieqlidhirqsgsdgrkvahaysllvkeahalsalhwghishylvhggk.............................
Q12IK0_SHEDO/5-391 ...................................................TTNTYAFDQWIRHRFVELNDELEVLYFQ.QSDK.ANV.A...G..I..GQDIKLALENEGRALIKSLLLE...GNTD...QGFD.AAFDLLGNVGLYMAACRRH..EITEP..SRETHSPLTEA.S..ALAMHIGASIGVTPRFATAHLTSHNSAINGTYKRFTSLADEKLFVDYNTRGILAYKRAADALL..KI..QP.LGISHPISHDLLIVCQQA...LQQVIDSNAILFE.....RLDSERFF.N.CVRPY...............YKPYRVG.SQVFRGANAGDFAGINVIDLQLGLC.V...A.....N...D..PS...YSQLLVDKFLYMMPEDQTLLRDCMRRESLMNDFLNAR.E.H..S.QQ.....AW..YQANLREFLTACELH.GA.TAIQHHEQLVSKYITAPSKQLGQQHLDT......VTASGPPLEVLLASLEKL.K.D.K.RAASP.RRDIATRFDDIEALKASL.................................................................................
G4QG60_GLANF/7-397 ..................................................t-AAVKNFDLWIRNDFKQLNTQLEEIYFA.QSDR.SDV.NcqtS..V..TKPLTNELTEAGRTYIAALLKE...GNTD...SGFD.AGFDLLGNVGLYMAACRRH..DITEP..SRETKSPLIEA.S..ALAMQIGASLGVTPRFSTSHLTTHNSAINGLYKSFTSLEDEILFLDYNTRGILAYMRTADALL..KI..LP.MGISHPLTGDMLHVAKQG...LQDVIKYNDILFN.....ELNVERFF.H.CVRPY...............YKPYRVG.QNEYRGANAGDFAGINVIDLLLGVC.Q...G.....D...D..PY...YSQILVDKFLFMLPEEQATLRDCMRRESLLDSMLSVT.P.E..Q.IS....sPW..FKENGALFLEVLELH.GY.AASQHHNQLVERFIAQMAKNESQQAYEK......VTASGPPLPVLLRSLEKL.K.D.L.RCATE.RDDIPSRYAEIQLLKAR-i................................................................................
A0A371REP4_9PROT/14-400 ................................................gas---AARFDHWIRTDFVELNTQLEELYFA.QSDK.ANV.A...G..V..GDDLKDALRRGGHEHIVALWRE...GNTD...DGFD.SAFGVLGNVGLYMGALRRH..ELTNP..DTEDRSPFPEA.S..SLALHIGATIGMAPRFATAHLATHNYAVNGVRKSYTSLKDEFLFIDENTRGILALTEAAEALA..RI..VP.LGVSNMVALDLFESAAKS...LERAIKINQGLFD.....NLDRDRFF.Y.CVRPY...............YKPYRVG.REVYRGANAGDFAGINQLDLLLGLT.R...A.....S...D..PY...YAQLLVDKLLFMTPGDQAKLKDTMRYPSLLDSLLGLA.G.H..A.EA.....DW..FKRAGAAYLKVADLF.AE.TARQHHDNLVKKFIVGPSDDLGDQHLQQ......VTASGPPLPVLIRALEKL.R.D.F.RTAAK.RDDIETRADDIAKLREL-v................................................................................
A0A563F2Q4_9PSEU/14-323 ........................................eevataslpdl----------------------------.----.---.-...-..-..----------------------...----...----.--LAMMRDLGILLGSVKRH..G-VEP..VA--VAPELEE.V..-LPLIARRSGMVIPRDTIYHYVLWNPV-GPRERLYTGLPMERMLMSAVRVALPMLSTAVDVCT..SL..DD.ATPGELAFATSVNELATL...VGTMRDSMDLVIA.....NVGPEFFA.R.TMRPY...............FQDIRVG.DDTWLGPAAAHVP-VALIDLRVWAS.D...H.....A...D..DC...YLDFVDHSAWYALERWRPLYRDWQRGPSLVSRVVEAL.E.R..H.PR.....--..--QDVPYVIN----A.SA.EALCRTMRALTVFRGKHLSIAREAYAPDtg..lyELGSGGGSVALLENV---.-.-.-.-----.------------------mnqardmatlvrlntsgtrrr............................................................
A0A3R9UH24_9ACTN/11-361 .........................diraadplgadallaavpamnaradt----------------------------.----.---.A...A..L..TVALRALIPDQDRA--------...--AL...WSVG.AALAAMRDLGILLGSLKRH..G-VQP..LA--AVPEALP.V..-LEL-LGRRTDMVPRDTVHHYTTWNPPG-PRRRSYTGHPTEARLQEAVRMVFPGLVAALDDCS..RV..AR.LEPYDPCFAAALDRIARH...VRAMVDAIDLTVA.....EVSPEYFA.V.TLRPY...............FEEVEVA.GRDYLGPAAAQVP-LWLVDLTLWQC.D...R.....S...D..AA...YDAFLAESLPYALPAWREFHARHRGGVSAVSKLSAAV.S.W..E.EV.....DR..LPPEL--------MD.SA.AALGRVLRILKTFRARHIGVARKAYSDDlr..lyEEGSGGAPVALLRSILDL.T.ReN.ETMVR.RATVRRR-----------paga.............................................................................
#=GC seq_cons ..................................................h.....................h..h.....tt....h.....s..h..ht.h+t.l.t.st..............st....uhs.puhshltslGhahuuh+RH..t.s-P..sp..hsPhhps.s..hLsh.lGsshGhsPR.sstHhooaN.shssth+pFTshssEtlFl-hsshuhhuhpcAs-sLh..cl...s.lulscPhhssLLppspps...Lpsllcu.ptlhp.....plss-hFa.h.slRPY...............acsh+VG.sp.YtGssAu-hu.lpllDllLhhC.c...s.....s...-..st...YsphLs-ph.YhhPccpthlccshppsSlhschLpth.s.t..p.tp......h..hptshphhh..h.ht.ut.sAht+p.pllppFhsp.st.hppta.pc.......suSGsshssLLptLtcL.p.-...Rsut..p.................h................................................................................
//
