GenomeNet

Database: Pfam
Entry: Proho_convert
LinkDB: Proho_convert
Original site: Proho_convert 
#=GF ID   Proho_convert
#=GF AC   PF12177.8
#=GF DE   Prohormone convertase enzyme
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Gavin OL;
#=GF SE   pdb_2ke3
#=GF GA   25.00 25.00;
#=GF TC   25.00 34.50;
#=GF NC   23.80 17.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   19376969
#=GF RT   Functional and structural characterization of a dense core
#=GF RT   secretory granule sorting domain from the PC1/3 protease.
#=GF RA   Dikeakos JD, Di Lello P, Lacombe MJ, Ghirlando R, Legault P,
#=GF RA   Reudelhuber TL, Omichinski JG;
#=GF RL   Proc Natl Acad Sci U S A. 2009;106:7408-7413.
#=GF DR   INTERPRO; IPR022005;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain family is found in eukaryotes, and is approximately
#=GF CC   40 amino acids in length. The family is found in association
#=GF CC   with Pfam:PF01483, Pfam:PF00082. There are two completely
#=GF CC   conserved residues (Y and D) that may be functionally important.
#=GF CC   This protein is the C terminal domain of a prohormone convertase
#=GF CC   enzyme which targets hormones in dense core secretory granules.
#=GF CC   This C terminal tail domain is the domain responsible for
#=GF CC   targeting these dense core secretory granules. The domain adopts
#=GF CC   an alpha helical structure. 
#=GF SQ   126
#=GS H2UMM7_TAKRU/715-753      AC H2UMM7.1
#=GS G3P2G0_GASAC/737-775      AC G3P2G0.1
#=GS A0A091VCH7_NIPNI/648-686  AC A0A091VCH7.1
#=GS K7AIY0_PANTR/642-680      AC K7AIY0.1
#=GS A0A091JK71_EGRGA/665-703  AC A0A091JK71.1
#=GS H0X116_OTOGA/714-752      AC H0X116.1
#=GS A0A091IAT4_CALAN/655-693  AC A0A091IAT4.1
#=GS F1MFR6_BOVIN/713-751      AC F1MFR6.2
#=GS A0A1U8D770_ALLSI/731-769  AC A0A1U8D770.1
#=GS A0A2I3HMV3_NOMLE/622-660  AC A0A2I3HMV3.1
#=GS A0A093ER99_GAVST/648-686  AC A0A093ER99.1
#=GS A0A1V4L147_PATFA/726-764  AC A0A1V4L147.1
#=GS A0A1U7SRB1_TARSY/713-751  AC A0A1U7SRB1.1
#=GS A0A093P8H3_PYGAD/656-694  AC A0A093P8H3.1
#=GS A0A2K5NPR1_CERAT/638-676  AC A0A2K5NPR1.1
#=GS F7DCC0_MACMU/638-676      AC F7DCC0.2
#=GS H2QR92_PANTR/713-751      AC H2QR92.1
#=GS A0A0G2JX54_RAT/588-626    AC A0A0G2JX54.1
#=GS A0A091TVP5_PHALP/656-694  AC A0A091TVP5.1
#=GS A0A1U7SY08_TARSY/589-627  AC A0A1U7SY08.1
#=GS A0A091L059_CATAU/656-694  AC A0A091L059.1
#=GS A0A091Q0I1_LEPDC/653-691  AC A0A091Q0I1.1
#=GS F7GI61_MONDO/716-754      AC F7GI61.1
#=GS A0A2I0LZF4_COLLI/656-694  AC A0A2I0LZF4.1
#=GS A0A1L8HR72_XENLA/701-739  AC A0A1L8HR72.1
#=GS W5Q845_SHEEP/713-751      AC W5Q845.1
#=GS A0A091QN03_MERNU/461-499  AC A0A091QN03.1
#=GS A0A087XXH9_POEFO/737-766  AC A0A087XXH9.2
#=GS H2LXE5_ORYLA/704-742      AC H2LXE5.1
#=GS M3XZ36_MUSPF/713-751      AC M3XZ36.1
#=GS NEC1_HUMAN/713-751        AC P29120.2
#=GS A0A0Q3PL92_AMAAE/708-746  AC A0A0Q3PL92.1
#=GS F6Z764_ORNAN/588-626      AC F6Z764.2
#=GS A0A091T3E9_9AVES/648-686  AC A0A091T3E9.1
#=GS A0A1D5NXP3_CHICK/584-622  AC A0A1D5NXP3.1
#=GS W5KGZ8_ASTMX/713-751      AC W5KGZ8.1
#=GS A0A2K5I2L5_COLAP/709-747  AC A0A2K5I2L5.1
#=GS A0A087QIT1_APTFO/656-694  AC A0A087QIT1.1
#=GS A0A226NHB3_CALSU/708-746  AC A0A226NHB3.1
#=GS A0A2K5I2Q5_COLAP/638-676  AC A0A2K5I2Q5.1
#=GS G1RV16_NOMLE/688-726      AC G1RV16.2
#=GS NEC1_RAT/712-750          AC P28840.1
#=GS L5KJL9_PTEAL/706-744      AC L5KJL9.1
#=GS A0A1S3A632_ERIEU/713-751  AC A0A1S3A632.1
#=GS A0A218UMC8_9PASE/709-747  AC A0A218UMC8.1
#=GS B6VCA1_DANRE/714-752      AC B6VCA1.1
#=GS K7GI54_PELSI/708-746      AC K7GI54.1
#=GS A0A096MPL7_PAPAN/709-747  AC A0A096MPL7.1
#=GS A0A093GXD3_STRCA/642-680  AC A0A093GXD3.1
#=GS NEC1_BOVIN/713-751        AC Q9GLR1.1
#=GS A0A094LBR1_9AVES/656-694  AC A0A094LBR1.1
#=GS D2HUX9_AILME/713-751      AC D2HUX9.1
#=GS H0VGG0_CAVPO/715-753      AC H0VGG0.1
#=GS F1RNV5_PIG/589-627        AC F1RNV5.3
#=GS A0A093J6A5_EURHL/504-542  AC A0A093J6A5.1
#=GS S7PRA2_MYOBR/767-805      AC S7PRA2.1
#=GS A0A094KYP4_ANTCR/660-698  AC A0A094KYP4.1
#=GS A0A087VL48_BALRE/656-694  AC A0A087VL48.1
#=GS A0A096LWJ8_POEFO/721-759  AC A0A096LWJ8.1
#=GS A0A1L8I1P1_XENLA/792-830  AC A0A1L8I1P1.1
#=GS A0A093SDE6_9PASS/659-697  AC A0A093SDE6.1
#=GS A0A099Z1B3_TINGU/644-682  AC A0A099Z1B3.1
#=GS I3MFI9_ICTTR/713-751      AC I3MFI9.2
#=GS A0A2G9SA06_LITCT/475-513  AC A0A2G9SA06.1
#=GS H3AFD1_LATCH/622-660      AC H3AFD1.1
#=GS A0A1A6FXP9_NEOLE/85-123   AC A0A1A6FXP9.1
#=GS A0A091H9K3_BUCRH/639-677  AC A0A091H9K3.1
#=GS A0A091EPD8_CORBR/661-699  AC A0A091EPD8.1
#=GS A0A093BA31_CHAPE/646-684  AC A0A093BA31.1
#=GS W5LZN5_LEPOC/703-733      AC W5LZN5.1
#=GS A0A2D0T2A7_ICTPU/729-766  AC A0A2D0T2A7.1
#=GS G7P7Z4_MACFA/713-751      AC G7P7Z4.1
#=GS M3ZTQ7_XIPMA/733-771      AC M3ZTQ7.1
#=GS F6TCF0_HORSE/714-752      AC F6TCF0.1
#=GS A0A091G706_9AVES/649-687  AC A0A091G706.1
#=GS H2UMM8_TAKRU/782-820      AC H2UMM8.1
#=GS F7B6Y5_CALJA/665-703      AC F7B6Y5.1
#=GS A0A2I4BXN5_9TELE/736-774  AC A0A2I4BXN5.1
#=GS G3H754_CRIGR/587-625      AC G3H754.1
#=GS A0A2I3MV42_PAPAN/638-676  AC A0A2I3MV42.1
#=GS G3VJH4_SARHA/712-750      AC G3VJH4.1
#=GS A0A091WC82_OPIHO/653-691  AC A0A091WC82.1
#=GS E9QIE6_DANRE/713-751      AC E9QIE6.1
#=GS G3SVS6_LOXAF/713-751      AC G3SVS6.1
#=GS G1KMV9_ANOCA/868-906      AC G1KMV9.2
#=GS V8P1Y2_OPHHA/696-734      AC V8P1Y2.1
#=GS A0A093G5M5_DRYPU/643-681  AC A0A093G5M5.1
#=GS H9FVB9_MACMU/709-747      AC H9FVB9.1
#=GS A0A226P6P6_COLVI/651-689  AC A0A226P6P6.1
#=GS A0A1S3P5Z7_SALSA/738-776  AC A0A1S3P5Z7.1
#=GS G5BU25_HETGA/715-753      AC G5BU25.1
#=GS U3JJX3_FICAL/709-747      AC U3JJX3.1
#=GS NEC1_MOUSE/713-751        AC P63239.1
#=GS NEC1_MOUSE/713-751        DR PDB; 2KE3 A; 713-751;
#=GS NEC1_MOUSE/713-751        DR PDB; 2KDT A; 713-751;
#=GS G1T2Q3_RABIT/712-750      AC G1T2Q3.1
#=GS E2QX69_CANLF/713-751      AC E2QX69.1
#=GS A0A1D5QZJ3_MACMU/641-679  AC A0A1D5QZJ3.1
#=GS G3QVR2_GORGO/713-751      AC G3QVR2.1
#=GS S9WAG8_CAMFR/113-151      AC S9WAG8.1
#=GS A0A1S3FN75_DIPOR/712-750  AC A0A1S3FN75.1
#=GS I3KX34_ORENI/728-766      AC I3KX34.1
#=GS A0A1V4L1Q1_PATFA/734-772  AC A0A1V4L1Q1.1
#=GS G1P8D0_MYOLU/713-751      AC G1P8D0.1
#=GS A0A0A0ADZ2_CHAVO/640-678  AC A0A0A0ADZ2.1
#=GS A0A0D9RPD1_CHLSB/709-747  AC A0A0D9RPD1.1
#=GS A0A2I3HQT2_NOMLE/698-736  AC A0A2I3HQT2.1
#=GS F7EBE4_CALJA/712-750      AC F7EBE4.1
#=GS H2PG51_PONAB/713-751      AC H2PG51.1
#=GS M3W5Q0_FELCA/713-751      AC M3W5Q0.1
#=GS A0A1S3L979_SALSA/735-773  AC A0A1S3L979.1
#=GS A0A091L0L3_9GRUI/641-679  AC A0A091L0L3.1
#=GS R0K3G2_ANAPL/652-690      AC R0K3G2.1
#=GS M7BZ79_CHEMY/664-702      AC M7BZ79.1
#=GS A0A091PNK8_HALAL/656-694  AC A0A091PNK8.1
#=GS A0A0N8JYZ4_9TELE/725-763  AC A0A0N8JYZ4.1
#=GS A0A1S3P651_SALSA/730-768  AC A0A1S3P651.1
#=GS A0A2I3HL19_NOMLE/666-704  AC A0A2I3HL19.1
#=GS A0A091DTA5_FUKDA/714-752  AC A0A091DTA5.1
#=GS A0A2I3GED9_NOMLE/704-742  AC A0A2I3GED9.1
#=GS A0A2I3TD29_PANTR/666-704  AC A0A2I3TD29.1
#=GS F1NB95_CHICK/708-746      AC F1NB95.2
#=GS A0A0F8AX79_LARCR/725-763  AC A0A0F8AX79.1
#=GS A0A2I2Z2B7_GORGO/642-680  AC A0A2I2Z2B7.1
#=GS A0A2I2Y9A9_GORGO/666-704  AC A0A2I2Y9A9.1
#=GS A0A0F8CAY7_LARCR/102-140  AC A0A0F8CAY7.1
#=GS A0A2K5NPA9_CERAT/709-747  AC A0A2K5NPA9.1
#=GS H3CZ93_TETNG/701-739      AC H3CZ93.1
H2UMM7_TAKRU/715-753                 ........YGGPEDNVYSDYADGFYRTKPYRHRDDRLLQALFQMIGD.
G3P2G0_GASAC/737-775                 ........YQGPEDSVYSDYSDGFYSIKPYRHRDDRLLQALFEMIDG.
A0A091VCH7_NIPNI/648-686             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
K7AIY0_PANTR/642-680                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A091JK71_EGRGA/665-703             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
H0X116_OTOGA/714-752                 ........LKDSDDSLYHDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A091IAT4_CALAN/655-693             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
F1MFR6_BOVIN/713-751                 ........LKDSEDSLYNDYVDGFYNTKPYKHRDDRLLQALVDLLRE.
A0A1U8D770_ALLSI/731-769             ........LRDSEESLYSDYVDLFYNTKSYKHRDDRLLQALVDILNE.
A0A2I3HMV3_NOMLE/622-660             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A093ER99_GAVST/648-686             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A1V4L147_PATFA/726-764             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A1U7SRB1_TARSY/713-751             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A093P8H3_PYGAD/656-694             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A2K5NPR1_CERAT/638-676             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
F7DCC0_MACMU/638-676                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
H2QR92_PANTR/713-751                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A0G2JX54_RAT/588-626               .......l-EDSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNE.
A0A091TVP5_PHALP/656-694             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A1U7SY08_TARSY/589-627             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A091L059_CATAU/656-694             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A091Q0I1_LEPDC/653-691             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
F7GI61_MONDO/716-754                 .......l-KNDENSLYSDYVDLFYNTKPYKHRDDRLLQALVDILKE.
A0A2I0LZF4_COLLI/656-694             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A1L8HR72_XENLA/701-739             .......g-REKENNLYNEYIDRFYHTRPYKHRDDRLLQALLNILKK.
W5Q845_SHEEP/713-751                 ........LKDSEDSLYNDYVDGFYNTKPYKHRDDRLLQALVDLLRE.
A0A091QN03_MERNU/461-499             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIVNE.
A0A087XXH9_POEFO/737-766             ........FSGPGDSLYSDYSDSFYSIKPYKHRNDRLL---------.
H2LXE5_ORYLA/704-742                 ........YHGAGDNIYSDYSDGFYNIKPYRHRDDRLMQALFQMLDD.
M3XZ36_MUSPF/713-751                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILRE.
NEC1_HUMAN/713-751                   ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A0Q3PL92_AMAAE/708-746             .......m-RGSEESLYSDYVDLFYNARPYKHRDDRLLQALIDIVNE.
F6Z764_ORNAN/588-626                 .......i-RDSEDSLYGDDVDVFYNTKPYKHRDDLLRQALLNILNG.
A0A091T3E9_9AVES/648-686             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A1D5NXP3_CHICK/584-622             ........LKDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
W5KGZ8_ASTMX/713-751                 .......h-RNPESSLYNHYRDSFYRNRAYRHRDEQLLQALFDMLDG.
A0A2K5I2L5_COLAP/709-747             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A087QIT1_APTFO/656-694             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A226NHB3_CALSU/708-746             ........LKDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A2K5I2Q5_COLAP/638-676             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
G1RV16_NOMLE/688-726                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
NEC1_RAT/712-750                     .......l-EDSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNE.
L5KJL9_PTEAL/706-744                 .......l-KEAEDSLYNNYLDGFYNTKPYKHRDDRLLQALMDILRE.
A0A1S3A632_ERIEU/713-751             ........LKDSEDSLYNDYVDGFYNTKPYKHRDDRLLQALVDILRD.
A0A218UMC8_9PASE/709-747             ........LRGSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
B6VCA1_DANRE/714-752                 ........YRASQNGLFNDYSDNFYRAQPYRHRDDRLLQALFDMLRD.
K7GI54_PELSI/708-746                 ........LKDSEDNLYSDYVDLFYNAKPYKHRDDRLLQALVDILNE.
A0A096MPL7_PAPAN/709-747             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A093GXD3_STRCA/642-680             ........LKDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDILNE.
NEC1_BOVIN/713-751                   ........LKDSEDSLYNDYVDGFYNTKPYKHRDDRLLQALVDLLRE.
A0A094LBR1_9AVES/656-694             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDILNE.
D2HUX9_AILME/713-751                 ........LKDSEDSLYSDYVDVFYNTKPYKHRDDRLLQALVDILRE.
H0VGG0_CAVPO/715-753                 ........LKDSEDTLYHDYVDVFYNTKPYKHRDDRLLQALVDILNE.
F1RNV5_PIG/589-627                   ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILRE.
A0A093J6A5_EURHL/504-542             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVAIIS-e
S7PRA2_MYOBR/767-805                 .......l-KDTEDSLYNDYADVFYNTKPYKHRDDRLLQALVDILRE.
A0A094KYP4_ANTCR/660-698             ........LRDSEESLYSDYIDLFYNAKPYKHRDDRLLQALVDIINE.
A0A087VL48_BALRE/656-694             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A096LWJ8_POEFO/721-759             ........FSGPGDSLYSDYSDSFYSIKPYKHRNDRLLQALFEMLDD.
A0A1L8I1P1_XENLA/792-830             .......g-RDRENNLYNEYIDRFYHSRPYKHRDDRLLQALLTILKK.
A0A093SDE6_9PASS/659-697             ........LRGSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A099Z1B3_TINGU/644-682             ........LKDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDILNE.
I3MFI9_ICTTR/713-751                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A2G9SA06_LITCT/475-513             .......a-KDKGNNLYNDYIDRFYNRRPYKHRDDRLLQALLNIVD-k
H3AFD1_LATCH/622-660                 .......q-KDSEDDLYNDYSDLFYNVKPYRHRDDRLLQALFELLKK.
A0A1A6FXP9_NEOLE/85-123              .......l-EDAEDSLYSDYVDVFYNTKSYKHRDDRLLQALVDILNE.
A0A091H9K3_BUCRH/639-677             ........LRGSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A091EPD8_CORBR/661-699             ........LRGSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A093BA31_CHAPE/646-684             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIVS-e
W5LZN5_LEPOC/703-733                 gqysqpsa----------------YSATPYRHRDGRLLQAFVDMLTE.
A0A2D0T2A7_ICTPU/729-766             ......tv---PENNLYNDYSDNFYRAQAYRHRDDRLMQALFDMLE-g
G7P7Z4_MACFA/713-751                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
M3ZTQ7_XIPMA/733-771                 ........FSGPGDSLYSDYSDGFYNIKPYKHRNDRLLQALFEMLDD.
F6TCF0_HORSE/714-752                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILRE.
A0A091G706_9AVES/649-687             ........LRDSEENLYSDYVDLFYNAKPYKHRDDRLLQALIDILNE.
H2UMM8_TAKRU/782-820                 ........YGGPEDNVYSDYADGFYRTKPYRHRDDRLLQALFQMIGD.
F7B6Y5_CALJA/665-703                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A2I4BXN5_9TELE/736-774             ........YRGPEDSLYSDYSDGFYNIKPYRHRDDRLLQALFQMLDD.
G3H754_CRIGR/587-625                 ........LKDSEDSLYSDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A2I3MV42_PAPAN/638-676             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
G3VJH4_SARHA/712-750                 ........LRNAENSLYSDYVDLFYSTKPYKHRDDRLLQALVDILKE.
A0A091WC82_OPIHO/653-691             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
E9QIE6_DANRE/713-751                 ........YRASQNGLFNDYSDNFYRAQPYRHRDDRLLQALFDMLRD.
G3SVS6_LOXAF/713-751                 ........LRDPEDSVYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
G1KMV9_ANOCA/868-906                 ........LKDSEESLYNDYVDLFYNSKPYKHRDDRLLQALVDILND.
V8P1Y2_OPHHA/696-734                 ........LRDSEESLYSDYVDLFYNSKSYKHRDDRLLQALVDILNE.
A0A093G5M5_DRYPU/643-681             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIIKE.
H9FVB9_MACMU/709-747                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A226P6P6_COLVI/651-689             ........LKDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A1S3P5Z7_SALSA/738-776             ......ra--GQDDSLYSDYSDGFYSSKPYRHRDDRLLQALFNMLSD.
G5BU25_HETGA/715-753                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
U3JJX3_FICAL/709-747                 ........LRGSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
NEC1_MOUSE/713-751                   .......l-EGSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNE.
#=GR NEC1_MOUSE/713-751        SS    .......S-SSS-SSSSHHHHHCCCT---SS-SCHHHHHHHHHHCCC.
G1T2Q3_RABIT/712-750                 .......l-QDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
E2QX69_CANLF/713-751                 ........LKDSEDNLYSDYVDVFYNTKPYKHRDDRLLQALVDILRE.
A0A1D5QZJ3_MACMU/641-679             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
G3QVR2_GORGO/713-751                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
S9WAG8_CAMFR/113-151                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILRE.
A0A1S3FN75_DIPOR/712-750             ........LKDSEDSLYNDYVDVFYNRKPYKHRDDRLLQALVDILSE.
I3KX34_ORENI/728-766                 ........YRSPEDSVYSDYSDGFYSTKPYRHRDDRLLQALFEMLDD.
A0A1V4L1Q1_PATFA/734-772             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
G1P8D0_MYOLU/713-751                 .......l-KDTEDSLYNDYADVFYNTKPYKHRDDRLLQALVDILRE.
A0A0A0ADZ2_CHAVO/640-678             ........LRDSEENLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A0D9RPD1_CHLSB/709-747             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A2I3HQT2_NOMLE/698-736             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
F7EBE4_CALJA/712-750                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
H2PG51_PONAB/713-751                 ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
M3W5Q0_FELCA/713-751                 .......l-KESEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILRE.
A0A1S3L979_SALSA/735-773             .......l-SGQDNSLYSDYSDGFYSTKPYRHRDDRLLQALFDMLSD.
A0A091L0L3_9GRUI/641-679             .......l-RHSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
R0K3G2_ANAPL/652-690                 ........LKDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
M7BZ79_CHEMY/664-702                 ........LKDSEDTLYSDYIDLFYNAKPYKHRDDRLLQALVDILNE.
A0A091PNK8_HALAL/656-694             ........LRDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A0N8JYZ4_9TELE/725-763             ........YRGSEENLYSDYSDVFYNAKPYKHRDDRLLQALFDMITE.
A0A1S3P651_SALSA/730-768             ......ra--GQDDSLYSDYSDGFYSSKPYRHRDDRLLQALFNMLSD.
A0A2I3HL19_NOMLE/666-704             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A091DTA5_FUKDA/714-752             ........LKDSEDSLYNNYVDVFYNTKSYKHRDDRLLQALVDILNE.
A0A2I3GED9_NOMLE/704-742             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A2I3TD29_PANTR/666-704             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
F1NB95_CHICK/708-746                 ........LKDSEESLYSDYVDLFYNAKPYKHRDDRLLQALVDIINE.
A0A0F8AX79_LARCR/725-763             ........YRGSEDSVYSDYTDGFYSTKPYRHRDDRLLQALFEMID-n
A0A2I2Z2B7_GORGO/642-680             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A2I2Y9A9_GORGO/666-704             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
A0A0F8CAY7_LARCR/102-140             ........YRGSEDSVYSDYTDGFYSTKPYRHRDDRLLQALFEMID-n
A0A2K5NPA9_CERAT/709-747             ........LKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNE.
H3CZ93_TETNG/701-739                 ........YGGPEDSVYSDYADGFYRTKPYRHRDDRLLQALFQMIGD.
#=GC SS_cons                         .......S-SSS-SSSSHHHHHCCCT---SS-SCHHHHHHHHHHCCC.
#=GC seq_cons                        ........L+DSE-SLYsDYVDlFYNsKPYKHRDDRLLQALVDILNE.
//
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