GenomeNet

Database: Pfam
Entry: RE_Bpu10I
LinkDB: RE_Bpu10I
Original site: RE_Bpu10I 
#=GF ID   RE_Bpu10I
#=GF AC   PF09549.13
#=GF DE   Bpu10I restriction endonuclease
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Bateman A
#=GF GA   25.00 25.00;
#=GF TC   50.60 49.50;
#=GF NC   22.00 19.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0236
#=GF RN   [1]
#=GF RM   9461472
#=GF RT   Cloning and analysis of the four genes coding for Bpu10I
#=GF RT   restriction-modification enzymes. 
#=GF RA   Stankevicius K, Lubys A, Timinskas A, Vaitkevicius D, Janulaitis
#=GF RA   A; 
#=GF RL   Nucleic Acids Res. 1998;26:1084-1091.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR018577;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family includes the Bpu10I (recognises and cleaves CCTNAGC
#=GF CC   (-5/-2)) restriction endonucleases.
#=GF SQ   66
#=GS A9WKK7_CHLAA/27-244       AC A9WKK7.1
#=GS A0A433MWJ7_CHLFR/92-197   AC A0A433MWJ7.1
#=GS A0A0Q8I892_9RHIZ/74-241   AC A0A0Q8I892.1
#=GS H0IY25_9GAMM/47-262       AC H0IY25.1
#=GS A0A2D0H8R4_9NOSO/92-184   AC A0A2D0H8R4.1
#=GS A0A1V2M3A4_9FIRM/86-307   AC A0A1V2M3A4.1
#=GS G2I7M4_KOMMN/89-308       AC G2I7M4.1
#=GS A0A654E4P7_9BACT/97-253   AC A0A654E4P7.1
#=GS A0A257L024_9BACT/93-255   AC A0A257L024.1
#=GS A0A0M1JRN4_9CYAN/87-303   AC A0A0M1JRN4.1
#=GS A0A519J860_ACISP/87-290   AC A0A519J860.1
#=GS A0A1J1LM07_9CYAN/92-195   AC A0A1J1LM07.1
#=GS A0YIL0_LYNSP/85-289       AC A0YIL0.1
#=GS A0A2D0H8R4_9NOSO/188-322  AC A0A2D0H8R4.1
#=GS A0A1W2GNX3_9BACT/85-288   AC A0A1W2GNX3.1
#=GS A0A0G3WIL1_9BACT/96-258   AC A0A0G3WIL1.1
#=GS A0A1Z4USJ9_9CYAN/92-195   AC A0A1Z4USJ9.1
#=GS A0A1Z4NMM7_9CYAN/3-204    AC A0A1Z4NMM7.1
#=GS A0A1Y4M0D3_9FIRM/68-289   AC A0A1Y4M0D3.1
#=GS A0A2T1M1V5_9CHRO/183-322  AC A0A2T1M1V5.1
#=GS A0A0Q8I868_9RHIZ/81-254   AC A0A0Q8I868.1
#=GS K9PHS5_9CYAN/188-322      AC K9PHS5.1
#=GS A0A507SMR4_9MOLU/78-252   AC A0A507SMR4.1
#=GS A0A3N6NRJ2_9CYAN/20-223   AC A0A3N6NRJ2.1
#=GS A0A552AD71_MICAE/90-308   AC A0A552AD71.1
#=GS R5D302_9FIRM/86-277       AC R5D302.1
#=GS A0A2T1M1V5_9CHRO/92-188   AC A0A2T1M1V5.1
#=GS K7X035_9NOST/90-308       AC K7X035.1
#=GS A0A1D2PBN9_9CYAN/189-322  AC A0A1D2PBN9.1
#=GS D3RTN6_ALLVD/85-297       AC D3RTN6.1
#=GS A0A3A9J9A1_9FIRM/80-282   AC A0A3A9J9A1.1
#=GS A0A328VMC2_9CHLR/22-239   AC A0A328VMC2.1
#=GS D4ZWX4_ARTPN/85-288       AC D4ZWX4.1
#=GS A0A5P8VU70_9NOSO/92-184   AC A0A5P8VU70.1
#=GS A0A3A9FNM2_9BACT/85-288   AC A0A3A9FNM2.1
#=GS Q8YMV8_NOSS1/44-183       AC Q8YMV8.1
#=GS B7KH18_GLOC7/87-303       AC B7KH18.1
#=GS A0A6N6JMU3_9RHOB/80-287   AC A0A6N6JMU3.1
#=GS A0A3A9J679_9FIRM/94-249   AC A0A3A9J679.1
#=GS K9PHS5_9CYAN/92-184       AC K9PHS5.1
#=GS A7C792_9GAMM/1-81         AC A7C792.1
#=GS A6GAH0_9DELT/95-313       AC A6GAH0.1
#=GS A0A6N6JNR2_9RHOB/92-247   AC A0A6N6JNR2.1
#=GS A0A257L0A0_9BACT/74-278   AC A0A257L0A0.1
#=GS A0A1J1LGD6_9CYAN/87-303   AC A0A1J1LGD6.1
#=GS A0A368YV55_9FIRM/80-251   AC A0A368YV55.1
#=GS A0A553EJV5_9BACT/84-294   AC A0A553EJV5.1
#=GS A0A5P8VU70_9NOSO/185-322  AC A0A5P8VU70.1
#=GS V4JIR1_9GAMM/86-303       AC V4JIR1.1
#=GS A0A553DV67_9FLAO/93-254   AC A0A553DV67.1
#=GS A0A0M2KCP0_9GAMM/94-297   AC A0A0M2KCP0.1
#=GS D7E3Y7_NOSA0/14-116       AC D7E3Y7.1
#=GS A0A2S7XND1_9GAMM/85-288   AC A0A2S7XND1.1
#=GS A0A2S6CUS5_9CYAN/90-308   AC A0A2S6CUS5.1
#=GS K9VIQ8_9CYAN/87-305       AC K9VIQ8.1
#=GS A0A521G237_9DELT/85-288   AC A0A521G237.1
#=GS A0ZAC6_NODSP/87-303       AC A0ZAC6.1
#=GS A0A0D6EUL7_9PROT/85-288   AC A0A0D6EUL7.1
#=GS A0A1Z4USJ9_9CYAN/182-321  AC A0A1Z4USJ9.1
#=GS A0A654E3L1_9BACT/61-264   AC A0A654E3L1.1
#=GS S2W195_9ACTO/113-332      AC S2W195.1
#=GS A0A433MWJ7_CHLFR/189-322  AC A0A433MWJ7.1
#=GS A0A6P1AST7_9BACT/92-310   AC A0A6P1AST7.1
#=GS A0A261KNK8_9CYAN/87-303   AC A0A261KNK8.1
#=GS A0A1D2PBN9_9CYAN/92-196   AC A0A1D2PBN9.1
#=GS A0A421DLN9_9GAMM/91-294   AC A0A421DLN9.1
A9WKK7_CHLAA/27-244                  .........................................................................QLKLDNTVIEEFLPVLVSI...AF.-P..DF.....PD..-T..LDLGM.K.SCFGAIYFT.STAGIISTSPKARIRTKDHDFTISR..QM..YLKAS......FDPR..............Y.....AQ.GVD.Q.LEV.NLAYLCAECKTNLDKTMFQEACATAHDVKTVVPGAKYLIICEW..LDMI..PVSTAG....TDVDEVLILRKA..RR.LGAQTRSLFASYAGRVAGRELYARYLNDNPFAVDVFERFLTHVRLLLED.RSPDE.RD.VLERGWF.........................................
A0A433MWJ7_CHLFR/92-197              .........................................................................RSNLHSSVLEEFLYYLF-K...DL.TG..DF.....GE..NA..-LIGK.S.HTFKDIFFVpPKYSEMLKRPYARIEKKDHDFVIGA..TI..QVSFE......AAPP..............-.....PE.QDE.N.TGE.ILP----------------------------------------..----..------....------------..--.-------------------------------------------------.-----.--.-------llkeepstysevtvt..........................
A0A0Q8I892_9RHIZ/74-241              .......................................................................qe--GLQPSIIEEFFGYLF-C...NI.DG..DV.....GV..-D..LLRRP.A.SSFIGLIFNpSSVKTLVSSPEYTVRSKDHDFVLGA..SL..EMTIG......ADGA..............G.....PS.KT-.-.EKI.IVPAVAIECKRYLERNMLDECAGTAERIKKATPYCRYIVAAEF..LKMD..DASPEL....SQIDEIFVLRRQ..KN.LER----------------------------------------------.-----.--.-------rgeqlnpiyad..............................
H0IY25_9GAMM/47-262                  .........................................................................QLKLDNSIIEEFMPYLITK...CF.-P..EL.....KD..--..VSLGP.T.KCFSAAYFR.TSLASRRDSSGLSIRTKDQDFAIAK..KI..YLKSS......RQQS..............F.....QN.SE-.T.VET.YLGYVTAECKTNLDKTMFQEATATAHDVKSAIPGSKYFLLCEW..LDMT..PISTAP....TDIDEVLILRKS..KR.IASNKRKEFSTYKGRLKNADWFRDYLIMHPFEVSVFERLIGHIEGIMGD.EDPVE.NN.VLDDGFF.........................................
A0A2D0H8R4_9NOSO/92-184              .........................................................................RSNLHSSVLEEFLYYLF-K...DL.VR..DF.....GE..NA..-LIGK.S.HTFKDIFFVpPKYSEMLKRPYARIEKKDHDFVIGA..TI..QVSFE......AA--..............-.....--.---.-.---.-------------------------------------------..----..------....------------..--.-------------------------------------------------.-----.--.-------tppekdenpgeilpll.........................
A0A1V2M3A4_9FIRM/86-307              .........................................................................QLKLDNTVIEEFLPIFSNK...CI.EK..VF.....GK..TA..STISA.QvPVFSSMYFQ.SSLANPIVGGGMTIKSKKQDFSISR..KI..FLKSS......HSPD..............F.....KS.EEA.KvITT.HLGYVMAELKTNLDKTMFQEASATAHDIKLAVTGAKYFLLCDF..LDMK..PISTTT....TDIDEILILRKA..KR.INSNVRASFSTYSGRQNARQSYYNYLCQNPYSVDMMTRFIEHLLNSMSN.EELIE.KN.VLEIGYF.........................................
G2I7M4_KOMMN/89-308                  .........................................................................QLKLDNTILEEFLPRLFDA...RL.IP..GF.....AR..QN.gLECGP.K.ASFAGLSFE.SPLLAL-SGGGVYIKRKDQDFSVTR..RH..KMRIT......TPSN..............-.....PN.DIF.E.QDF.HVSYFATEIKTNLDKTMFQEAAATAGELKRVSSGSKYILLCEW..LDMT..PINTKL....TAMDEVIVLRRA..KR.IASNQRSEFSTAAGRQKKSQWYSDYLDKYPLSLDGFKRLIWHLNECFPA.EEHDS.EEiVLERGYF.........................................
A0A654E4P7_9BACT/97-253              ..qsdflssllpellylsyskiiqsahsdleittqkdiiidlsflpyndssitfkpkrvdvaivkkldvtigg-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....--.--E.A.LDF.SIPIVALEVKTNLDKNMISGVEYSVERLKRTFPLCKFYLVSEL..ADFAyeKQNYAG....TAIDEIIILRKQ..KR.S------------------------------------------------.-----.--.-------vvrknpkginn..............................
A0A257L024_9BACT/93-255              ......................................................................qsd---FLSSLLPEFLYLLYDK...FV.IS..QH.....KD..FI..IE-TQ.K.DLVIDLSFL.PYST-----SAINFKSKRVDVAILK..PC..SFKVN......KE--..............-.....--.--K.L.NDF.NIALIAIEVKTNLDKNMIGGVEYSVQRLKRTFPLCKYYLISEL..ADFAyeKQNYAA....SAIDEILITRKQ..KR.SE--VR-------------------------------------------.-----.--.-------rdstklnpidanl............................
A0A0M1JRN4_9CYAN/87-303              .........................................................................QLKLDNTILEEFLPQVVFR...SL.-R..GI.....DD..-S..FELGP.R.NTFAGLSFL.SSLGNLGQGGEPIIRSKDQDFILGK..KL..YLKSS......FDRE..............F.....QD.CK-.F.IES.HLGYVCAECKTNLDKTMFQEAVATSRDLKTAVPGSLYFIVCEF..LDMT..PVSLIS....TQIDDVLIVRKT..KR.MSSNIRQEYRTPEARRNHRQEYIDFLDSSRYYSDVFQRMIDKIQSLIDD.TSPSM.EN.VLNQGHF.........................................
A0A519J860_ACISP/87-290              .........................................................................RSNLHSSVLEEFIYYLF-R...DL.VY..SF.....SP..NA..-LLGK.A.HAFKDIFFQaSNFANMVTKPNTKIEKKDHDFVIGI..NV..HSKMH......CAGQ..............T.....EE.E--.I.DIF.QIPAVAIECKTYLDKTMLEASSTSAQQLMYKNPNAIYIVVAEW..LKLT.sNVNLRK....YKVDQIYVFRKQ..KN.TDREYR---------------YAETYIKNPIYPDVIEHLFNYVRKHLTT.DWENG.TAhGISKGYL.........................................
A0A1J1LM07_9CYAN/92-195              .........................................................................RSNLHSSVLEEFLYYLF-K...DL.VR..DF.....GS..NA..-LIGK.S.HTFKDIFFVsPKYSEMLKRPYARIEKKDHDFVIGA..TI..QASFE......AAT-..............-.....--.---.-.---.-------------------------------------------..----..------....------------..--.-------------------------------------------------.-----.--.-------ppeqdetpgelvtfvqqepesyseat...............
A0YIL0_LYNSP/85-289                  .........................................................................RSNLHSTVLEEFMYYLF-K...DL.VA..EF.....SE..YA..-LIGK.S.HTFKDIFFLpSSYRNMLRSPHALIERKDHDFAIGV..QVdaILQCR......GQTE..............-.....--.-RE.H.DSW.DIPAVAVECKTYLDKTMLQDASTAALQLKNKNPNALYIVVAEW..LKLT.nAVNLRK....YQIDQVYVLRKQ..KN.TDREFR---------------YLETYVKNPIYSDVVIHLFETVREFLSYpSWEGG.VNyGLQRGYL.........................................
A0A2D0H8R4_9NOSO/188-322             ................................................................penysevtv-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....TG.NTE.T.HIF.DIPVVAIECKTYLDKTMLEGSSRAAEDLKARNPNSLYVVLMEW..IKLT.sDVNLRK....YKVDQIYVLRQQ..KN.TDREFR---------------YEEKYLKNSINPVVVQHLFHKVRKHLKM.DWTGG.IEhGIERGWL.........................................
A0A1W2GNX3_9BACT/85-288              .........................................................................RSNLHSSVLEEFIYYLF-K...DI.VF..EF.....SE..HA..-QLGK.A.HAFKDIFFNaPNFREMVTKPYTKIEKKDHDFVIGV..NI..DTKMQ......VHGS..............-.....-T.DME.E.VTL.QIPAVAIECKTYLDKTMLEGSSTAAEQLKNKNPNGIYIVVSEW..LKLT.sQVNLGK....YKVDQIYVLRKQ..KN.TDREFR---------------YADDYEKNQIHEDVVEHLFSTVRDHLSS.DWEKG.VEyGLKKGFL.........................................
A0A0G3WIL1_9BACT/96-258              ........................................................................q-GKFRPTIMEEFMYLLFKDlflDI.KK..DL.....KD..QHnlINLGG.V.KAYTNLYFSaKNLKQFVENPIIGINNKNQDFAIYR..PI..DLKIN......NESV..............-.....--.---.-.QKI.NLPIIAIENKTYIDKTMLEGSIATAEKIKSGNPYSLFFIVTET..YEVD.sSVDPAY....SRIDQIFVLRKS..KN.KD-----------------------------------------------.-----.--.-------dgnk.....................................
A0A1Z4USJ9_9CYAN/92-195              .........................................................................RSNLHSSVLEEFLYYLF-R...DL.AK..DF.....GE..NA..-LIGK.S.HTFKDIFFVpPKYAEMLKRPYARIEKKDHDFVIGA..TI..EA--S......FEAV..............T.....PP.EEE.N.S--.-------------------------------------------..----..------....------------..--.-------------------------------------------------.-----.--.-------gemltiikeepdnysdvtv......................
A0A1Z4NMM7_9CYAN/3-204               ......................................................................eqe-------------------...--.--..--.....--..--..-----.K.PTFKDIFFVpPNYSEMLKRPYARIEKKDHDFVIGV..TI..QASLEaapppeTDPSlgemvtiikeepgtYseatvTG.NTE.T.HIF.DIPVVVIECKTYLDKTMLEGSSRAAEDLKARNPNSLYIVVMEW..IKLT.sDVNLRK....YKVDQIYVLRQQ..KN.TDREFR---------------YESKYVKNSINPAVVQHLFKKVRNYLTT.DWVGG.IEmGIQRGWL.........................................
A0A1Y4M0D3_9FIRM/68-289              .........................................................................QLKLDNTILEEFMPIFVKK...CI.TK..VQ.....GD..YD..IEISS.QiPTFSSVYFA.SSLSNPNIGGGINIKTKDQDFSMSR..KL..YLQSS......YDPQ..............F.....NP.LKTvK.LET.HLGYVLAEMKTNLDKTMFQEASATAHDIKQAVTGAKYYLLCDF..LDMT..PISTTT....TDIDEILIVRKA..KR.ISSNIRKEFSTRAGRDKWRDWYVKYLRDNPYSADIFKRFVSHVISQMSN.EELIE.ES.VLEVGYF.........................................
A0A2T1M1V5_9CHRO/183-322             ...........................................................ilkeepinysevtv-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....ID.NAE.T.HIF.DIPVVVIECKTYLDKTMLEGSSRAAEELKARNPNSLYIVVMEW..IKLT.nDVNLRK....YKVDQIYVLRQQ..KN.TDREDR--YKT-------------DYVKNPISATVVQHLFDKIRNYLTR.DWAEGlEQ.GLQRGWL.........................................
A0A0Q8I868_9RHIZ/81-254              .....................................................................rgdf----ASSLLPEFLFRVVLA...RL.-E..GL.....DV..-L..PLFSR.K.DSIVDITLN.S-----YREGGWTVRKKNQDLCIGL..RT..----D......TI--..............-.....VD.EKL.S.RTF.VVPLIAIEAKTNIDINKLNGLDFSADRLKRTFPAAKYYLVTET..LDFS..LSKNYS....GSIDEIFVLRKQ..MRsVSRRTK-------------------------------------------.-----.--.-------apycsdvfeefaedvahcmlradv.................
K9PHS5_9CYAN/188-322                 ................................................................penysqvtv-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....TG.NTE.T.HIF.DIPVVAIECKTYLDKTMLEGSSRAAEDLKARNPNSLYVVLMEW..IKLT.sDVNLRK....YKVDQIYVLRQQ..KN.TDREFR---------------YEENYIKNPMNPIVVQHLFHKIRKHLKM.DWTGG.IEhGIERGWL.........................................
A0A507SMR4_9MOLU/78-252              .........................................................................QSKFESSFLEEINCYLFQN...LL.--..PI.....KN..NE..LGIFN.K.RIFAGL---.----KINNEGKISLINKDVDFCIGI..KS..IIKIN......DQPG..............-.....--.---.-.ISL.TIPVVCVEVKTYLDATMFGEVKNSSSSIKYANPNSNMYLLCTY..LSIA..NEHIISargnSALNEIFVLKHN..KD.NLFDWKIFYD---------------------------------------.-----.--.-------yyceiencvmsykasdkitv.....................
A0A3N6NRJ2_9CYAN/20-223              .........................................................................RSNLHSSVLEEFMYYLF-K...DL.VQ..EF.....SS..QA..-LIGK.S.RTFKDIFFRsENYQYMLNYPYALIELKDNDFAIGV..RI..HAQMN......CQGS..............-.....-Q.ELE.S.HIW.DVTAVVIECKTYLDKTMLQDAATAAEQLKYRNPNAIYILVAEW..LKLT.dAVNLRK....FKIDQIYVLRKQ..KN.TDREFR---------------YQKGYVKNPIYVDVVEHLFVYVRDYLTS.DWEGG.INfGLKRGYL.........................................
A0A552AD71_MICAE/90-308              .........................................................................QLKLDNTIIEEFLPYLINP...II.IP..EI.....EK..LD..AEVGP.I.KAFSSVYFE.SSLTIPALGGGLSIRSKNQDFAITR..KL..YLKAS......HFPD..............F.....TQ.EK-.S.IIT.NLAYIAVECKTNLDKTMFQEGCATAHDVKTAVPGAKYFLVCEW..LDMS..PISTAP....TDIDEVILLRKA..KR.INSNIRTHFATYQGRLDYRDYYIQYLENNPFRIEVFQHLINNIRNLLNN.EGLDE.SN.VLEVGYF.........................................
R5D302_9FIRM/86-277                  .........................................................................QLKLDNTVIEEFLPIFVRK...CI.IK..EF.....GV..CD..VDIGS.QtATFSSAYFA.SSLSSPSIGGGLSIKTKDQDFSMSR..KL..YLRSS......YTPT..............F.....DV.EKTvT.VTT.HLGYVMAELKTNLDKTMYQEASATAHDIKLAVTGAKYYLLCDF..LDMT..PISTAT....TDIDEILIVRKA..KR.ISSNVRKEFSTFAGRQANREWYFQAV-----------------------.-----.--.-------hgrarpd..................................
A0A2T1M1V5_9CHRO/92-188              .........................................................................RSNLHSSVLEEFLYYLF-R...DL.AN..DF.....GE..NA..-LIGK.S.HTFKDIFFVpPKYSEMLKRPYARIEKKDHDFVIGA..TI..QASFE......AAPP..............P.....EQ.DKN.-.---.-------------------------------------------..----..------....------------..--.-------------------------------------------------.-----.--.-------lgevlpilkeep.............................
K7X035_9NOST/90-308                  .........................................................................QLKLDNTIIEEFLPYLINP...VI.VP..EI.....EN..LA..VDIGP.I.KTFSSVYFE.SSLTFPALGGGLSVRSKNQDFAITR..KL..YLKAS......HFPD..............F.....TQ.EK-.S.IIT.NLSYIAVECKTNLDKTMFQEGCATAHDVKTAVPGAKYFLLCEW..LDMS..PISTAP....TDIDEVILLRKA..KR.LNSNIRGNFATYEGRLDYRDYYIEYLKNNPFRVEVFKHLINNIRKLLKN.EGLDE.SN.VLEVGYF.........................................
A0A1D2PBN9_9CYAN/189-322             .................................................................gtysevtv-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....TG.NTE.T.HIF.DIPVVAIECKTYLDKTMLEGSSRAAEDLKARNPNSLYLVVMEW..IKLT.sDVNLRK....YKVDQIYVLRQQ..KN.TDREFR---------------YEATYVKNSINPVVVQHLFKKVRNHLTM.DWASG.IElGIQRGWL.........................................
D3RTN6_ALLVD/85-297                  .........................................................................QLKLDNSVLEEFLIHLIHP...AI.IP..GL.....PE..NL.eLNVGP.T.RAFMSLSFNpSGVAALGEKPSVVVKVKDQDFILGK..EI..YYKFS......PDHD..............F.....PD.STT.A.SGViPLAVLAAECKVNLDKTMFQEASGTAARLKQGCPHAQYFVLNEY..LDMS..PEDCRL....TAVDNVYLLRHA..KR.LPFNLRNDYDAVR-RQR---------DAHPIDPAVILRFVENIDAFVNA.VWYDP.NA.ALERGSF.........................................
A0A3A9J9A1_9FIRM/80-282              .........................................................................QVALGYTIMEEFFYLLFQK...KVdMM..NI.....EH..EN..LFVGK.G.NSYVSLSFTpSSFSELFNRPNAYIHTKDQDFVLGA..NV..EIQVT......ADGE..............-.....--.-IG.T.TTT.VIPAVAIECKTYLERNMLDACAATASRLKAAMPYCIYIVAAEY..MKMS..DAAPEL....TDIDEVYILCRA..KN.ADRERRK------------------------------------------.-----.--.-------renlapfdintdlivdlynrvsrhlnaiwwqpenavengki
A0A328VMC2_9CHLR/22-239              .........................................................................QTKLDNSIIEEFLPRLVQA...LL.GH..KL.....PP..-G..IHLGP.V.ESFSAIWFD.SSLIRREPGGGLSLRQKAQDFALSL..PL..YIRAS......HSPT..............F.....EG.SL-.E.LRT.NLAYIATECKTNLDKTMFQEACATARDLKSALPLAKYLLLCEW..LDMK..SINTGT....TPTDRVLILRKA..KR.ISAATREKFSTYQGRQSLKGTYLTFLRSHPYREEVFQLFISYIDQFLSQ.ETLDE.ET.VLDQGYF.........................................
D4ZWX4_ARTPN/85-288                  .........................................................................RSNLHSSVLEEFMYYLF-R...DL.VQ..EI.....SP..HA..-LLGK.A.HSFKDVFFRpPSYQEMLKKPYALIEIKDHDFAIGVsvET..QMKCE......GSPV..............-.....--.-VE.T.HNW.DIPAVAIACKTYLDKTMLQDISTAAEQLKYKNPNAMYIVVAEW..LKLT.dSVNLRK....YKIDQIYILRKQ..KN.TDREFR---------------YLESYQKNPIYSDVVQHLFLKVREFLIS.DWEGG.ISdGLNRGFL.........................................
A0A5P8VU70_9NOSO/92-184              .........................................................................RSNLHSSVLEEFLYYLF-K...DL.VR..DF.....GE..NA..-LIGK.S.HTFKDIFFVpPKYSEMLKRPYARIEKKDHDFVIGA..TI..QVSFE......AA--..............-.....--.---.-.---.-------------------------------------------..----..------....------------..--.-------------------------------------------------.-----.--.-------tppekdenpgeilpll.........................
A0A3A9FNM2_9BACT/85-288              .........................................................................RSNLHSSVLEEFIYYLF-K...DL.VR..DF.....SE..SA..-LLGK.S.HAFKDIFFMpKSYQEMVTKPCAKIERKDHDFVIGV..KI..NSDMI......CEGS..............-.....-T.TVE.R.VDF.QIPAVAIECKTYLDKTMLEGASTAGEQLKTRSPNALYIVVAEW..LKLT.eNVNIKK....YKVDQIYILRKQ..KN.TDREYR---------------YLPGYVKNPVYLDVVQHLFETVRNHLTS.DWEGG.IKfGLERGYL.........................................
Q8YMV8_NOSS1/44-183                  ...........................................................ilkeepdtysevtv-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....TG.NIE.T.HIF.DIPVVAIECKTYLDKTMLEGSSRAAEDLKARNPNSLYLVVMEW..IKLT.nDVNLRK....YKVDQIYVLRQQ..KN.TDREFR---------------YESTYIKNSINPTVVQHLFKKVQHHLIK.DWAGG.IEsGIQRGWL.........................................
B7KH18_GLOC7/87-303                  .........................................................................QLKLDNTILEEFLPQVVFR...SL.-R..GI.....DD..-S..FELGP.R.NTFSGLSFL.SSLGNLGQGGEPSIRTKDQDFILGK..KL..YLKSS......FDAE..............F.....QD.YK-.L.IES.HLGYVCAECKTNLDKTMFQEAVATSRDLKIAVPGSLYFLICEF..LDMT..PISIIS....TQIDDVLIVRKT..KR.MSSNIRQEYRTPEERQRHRQQYVDFLDSSQYYPDVFQRMINKIQALIDD.TSPSM.EN.VLNQGHF.........................................
A0A6N6JMU3_9RHOB/80-287              .........................................................................QENLRSTMMEELYAWLF-K...DI.FEllEI.....DQ..PL.nFKLGKsT.SSYVSLTFApHNFASIFNDPNPRIAKKDQDFAIGA..TF..QLTIQ......PEGG..............-.....-E.SPI.K.SGI.LIPIVAIECKTYLAKNHLDMCASTAASIKTAAPYCMYVVSAEF..IKMD.kGVFPEL....TDISEIFVLCRA..KN.GDRKKRRD-----------------------------------------.-----.--.-------aglpphdihadlicdlfnrvighlrsiwwdpdsalksgrv.
A0A3A9J679_9FIRM/94-249              ......qadftssiipemlclifnhviqstglnlevsaqkdltiecifdivgggemrfknkrvdvavvepckl-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..----S......LNE-..............-.....--.--Q.T.TEF.PIPLLAIECKTNLDKNMLSGIEHSVAEMKKTFPNCQYFVITEC..SDFNvkKSNYAS....SGIDEIYILRKQ..KR.-------------------------------------------------.-----.--.-------gvirrapdlrn..............................
K9PHS5_9CYAN/92-184                  .........................................................................RSNLHSSVLEEFLYYLF-R...DL.VR..DF.....GE..NA..-LIGK.S.HTFKDIFFVpPKYSEMLKRPYARIEKKDHDFVIGA..TI..QAS--......----..............-.....--.---.-.---.-------------------------------------------..----..------....------------..--.-------------------------------------------------.-----.--.-------laaavppekdknpgeilavf.....................
A7C792_9GAMM/1-81                    ........................................................................m-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....--.---.-.---.----------------------------------------IEY..LDML..PEDCRL....TEIDNVFLLRKT..KR.LPVNKR-SLSTEIEKQH---------KDFPISKEVMWHFVQEIQNFVDA.VWYDP.NA.ALERGSF.........................................
A6GAH0_9DELT/95-313                  .........................................................................QTKLDNSIIEEFLPILVTS...VF.GE..DL.....AD..DI..FELGP.T.TCFSNLRFE.SSIVELSKGAGAAVKSKDQDFAISR..PV..FLKTS......HHKD..............F.....RN.AT-.T.HET.RIAYVAAECKTNLDKTMFQEAAATAQDVKTAVPGAKYFLLCEW..LDMT..PISTSV....TPIDEILLMRRA..KR.LPSSARKSFSKAADRKANRGTFIEYLDGNPFSSKVFERLLSHIEQVVRA.DGLDT.NK.ALSDGFF.........................................
A0A6N6JNR2_9RHOB/92-247              qsdfitsvvpefflrmfhvlcadyeqlfasgqrdiaidvsfdtrmpsllmpkmqrvdlaigyvttltvgahas-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....--.---.-.TPL.FIPILAAEAKTYFDKNMISGVDFSATAIKNTFPHCQYLAMSEFadFDLQ..ALSYAA....SSIDEIYILRHQ..KR.SDF----------------------------------------------.-----.--.-------rksglakg.................................
A0A257L0A0_9BACT/74-278              .........................................................................QENLRSSMLEELFCHLFSDligEL.LP..SL.....PS..-N..LLLGK.A.NSYVDLTFSpSSFREIFIKPNPYIHSKDQDFVIGV..NL..ELKIK......ADGA..............-.....-N.EI-.K.EDI.IVPVLAIECKTYIERNMLDSCSGTARRLKSAMPYCLYIVASEY..MKLK..DEQPEL....SDINEIYILCKA..SV.------------SERLDSRK---RGIKPHIIQEDLIIDLFNKVKGHLNS.IWWSP.DK.ALSTG--ki.......................................
A0A1J1LGD6_9CYAN/87-303              .........................................................................QLKLDNTILEEFLPQLIYR...SL.-Q..GI.....DE..-S..FEIGP.R.NTFSGLSFL.SSLGNIGQGGEPSLRTKNQDFVLGK..KL..YLKTA......FDSG..............F.....HN.YK-.L.LES.HLGYVCAECKTNLDKTMFQEAVATSRDLKIAVPASLYFLVCEF..LDMM..PVSIIS....TQIDDVLIVRKN..KR.LPANIRQQYKTPESRKRYRQSYADFLDSSKYYPDVFQRMINKIQILIDD.TAPEI.DK.ILKRGHF.........................................
A0A368YV55_9FIRM/80-251              .........................................................................QSKFRSTILEEFMGYLF-K...DI.-P..EI.....EG..MG..LEFNN.K.NIFAGIK--.-----LDHNGNINIQTKDVDFCIGK..NF..DIYVD......AQ--..............-.....--.-KN.K.YEI.FIPIVAIECKTYLDKTMYSEAQFSAQKIKNGTPNAKTYIIMET..NEVA.lDKYSPQ....SPIDELYVLRKEtgKN.ISKEITYTF----------------------------------------.-----.--.-------fkelhedirqvnklneii.......................
A0A553EJV5_9BACT/84-294              .........................................................................QLKLDNSVIEEFLIHLVHD...DV.LT..GL.....PK..-G..IETGS.Q.TAFMSLTFRpSSIDALTERPEIVLKQKDQDFTIGK..SI..FYQFS......PNEK..............F.....EK.KVT.A.NGKlFLAVLAAEVKVNYDKTMFQECAGTASRLKQGCPLSKYYALVEY..LDMK..PEDVRL....TDIDNVFLLRKA..KR.LPFEKRSVFEEVRD----------QHKDCPINSDVMKMFVKEMQEFISA.TWYDA.EQ.ALKRGSF.........................................
A0A5P8VU70_9NOSO/185-322             .............................................................keepenysevtv-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....TG.NTE.T.HIF.DIPVVAIECKKYLDKTMLEGSSRAAEDLKARNPNSLYVVLMEW..IKLT.sDVNLRK....YKVDQIYVLRQQ..KN.TDREFR---------------YEEKYVKNSINPVVVQHLFHKVRKHLKM.DWTGG.IEhGIERGWL.........................................
V4JIR1_9GAMM/86-303                  .........................................................................QLKLDNTVIEEFLPYLITK...SL.-P..QL.....GE..-E..MYVGP.Q.SCFSAAYFT.STLTRHENGGGLHIRTKDQDFTIAK..KL..FIQTS......YDPS..............F.....RE.QVL.A.RET.YLGYICAECKTNLDKTMFQEASATAHDVKTAVPGAKYYLLCEW..LDMT..PISTAP....TDIDEVLLLRKA..KR.VGSQVRRHYATYRGRQQVREEYTEYLSDNPFAPDVFRRLVSHIEGVLND.QDPDE.GN.VLSGGYF.........................................
A0A553DV67_9FLAO/93-254              .........................................................................QSKFRPTIIEEFLYLLF-N...DL.IE..ELkiknkDE..KD.vLKVGT.I.KAYSNLYFTaKNLNNFINGPSVGINTKDQDFAIYR..PL..NLSIQ......DIG-..............-.....--.---.T.YST.NIPVVSIECKTYIDKTMLEGSIATAEKIKSGNPYSLFIIITET..YEVD.lKVDPVY....SRINQIYVLRKT..KR.KDAN---------------------------------------------.-----.--.-------q........................................
A0A0M2KCP0_9GAMM/94-297              .........................................................................RSNLHSSVLEEFMFYLF-K...DM.VE..EI.....SP..HA..-LIGK.T.HSFKDIFFRsKSYKDMVNKPSAIVEIKDHDFSIGI..TV..NAKMK......VNGS..............-.....-E.FYE.N.HLW.DIPALAIECKTYLDKTMLQDVSTAAEQLKLKNPNAVYIVVAEW..VKLT.eKVNLKK....YKVDQIYILRKQ..KN.TDRELR---------------YKAGYIKNPIYDEVVSHLFNTVRDFLTT.DWDSG.IAyGLQNGYL.........................................
D7E3Y7_NOSA0/14-116                  ...................................................................acmnns-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....--.---.-.---.---------------------------------SLLYFLVSEF..PDIT..PVSITS....TQIDYVLIVIKS..RH.ITSNVRQEYRTPETRKLYRQEYGDFIDASKYYPDVFQRMINKTQTLIDD.TAPGV.EQ.VLKLGNF.........................................
A0A2S7XND1_9GAMM/85-288              .........................................................................RSNLHSSVLEEFMYYLF-R...DL.VF..GI.....SE..YA..-LIGK.S.HSFKDIFFRaPSYLHMIKKPHALFEIKDHDFTIGAsvKT..TMKCR......GSAL..............-.....--.-IE.E.HDW.DIPAVAIECKTYLDKTMLQDVSTAAEQLKQKNPNAMYIVVAEW..LKLT.gSVNLKK....YKIDQIYVLRKQ..KN.TDREFR--YD-------------TNYQKNPIYDDVINHCFNSVREFLTS.DWEGG.IShGIDRGFL.........................................
A0A2S6CUS5_9CYAN/90-308              .........................................................................QLKLDNTIIEEFLPYLINP...II.IP..EI.....EK..LD..AEVGP.I.KAFSSVYFE.SSLTIPALGGGLSIRSKNQDFAITR..KL..YLKAS......HFPD..............F.....TQ.EK-.S.IIT.NLAYIAVECKTNLDKTMFQEGCATAHDVKTAVPGAKYFLVCEW..LDMS..PISTAP....TDIDEVILLRKA..KR.INSNIRTHFATYQGRLDYRDYYIQYLENNPFRIEVFQHLINNIRNLLNN.EGLDE.SN.VLEVGYF.........................................
K9VIQ8_9CYAN/87-305                  .........................................................................QLKLDNSIIEEFIPILVTT...VF.AD..SL.....KD..KE..LSFGP.T.QCFSSLRFE.SSLKLSPKGGGMSIRAKEQDFAISR..KI..FLKAS......HNQD..............F.....KE.TT-.S.REA.NIAYVAAECKTNLDKTMFQEGAATALDVKLSVPGAKYFLLCEW..LDMS..PISSSL....TAIDEILILRKA..KR.LTSNIRKDFSTVKGRKKNKDSFVNHLDNNPFAPEVFMRFLKEIEGMIGK.DELDE.DD.VLSRGYF.........................................
A0A521G237_9DELT/85-288              .........................................................................RSNLHSSVLEEFMYYLF-R...DL.VL..GI.....SE..NA..-LIGK.S.HSFKDVFFRpPSYKKMISSPHALFEIKDHDFAIGA..SV..RATMQ......CIGS..............T.....--.TTE.V.YDW.DIPAIAIECKTYLDKTMLQDVSTAAEQLKQKNPNAMYIVVAEW..LKLT.eSVNLKK....YKVDQIYVLRKQ..KN.TDREFR---------------YDAGYKKNPIYADFVEHCFNSIRDFLTA.DWEGG.IShGLERGFL.........................................
A0ZAC6_NODSP/87-303                  .........................................................................QLKLDNSILEEFLPQVIYR...SL.-K..GI.....DN..-T..FEVGP.K.KTFAGLSFL.SSLGNPGIGGEPTLRTKNQDFVLGK..KL..YLKTS......FDSQ..............F.....TS.SK-.L.VES.YLGYVCAECKTNLDKTMFQEAVATSRDLKLAVPSSLYFLVCEF..LDMT..PVSITA....TQIDDVLIVRKS..KR.ISANIRQEYKTPESRQQHRQEYADFIEMSKYYPDVFQKMIDKIQTLVDD.TAPKV.DQ.VLKRGHF.........................................
A0A0D6EUL7_9PROT/85-288              .........................................................................RSNLHSSVLEEFMYYLF-R...DL.VA..HI.....SP..YA..-LIGK.S.HSFKDLFFRaNSFDSLIKKPNALIEKKDHDFAIGT..SV..--KAE......MSCR..............G.....SD.EIE.L.HDW.DIPAVAIECKTYLDKTMLQDASTAAEQLKQKNPNALYIVVAEW..LKLT.eSVNLKK....YKIDQIYVLRKQ..KN.TDREFR--Y---D---------IDY-VKNPIYSDVIEHCFFTVRNFLIH.DWEGG.IShGLEKGFL.........................................
A0A1Z4USJ9_9CYAN/182-321             ............................................................iikeepdnysdvt-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............V.....TG.NTE.T.HIF.DIPVIVIECKTYLDKTMLEGSSRAAEDLKARNPNSLYIVLMEW..IKLT.sDVNLRK....YKVDQIYVLRQQ..KN.TDREFR---------------YEETYVKNPINPTVVQHLFHKVRKHLTM.DWSGG.IEyGIKRGWL.........................................
A0A654E3L1_9BACT/61-264              .........................................................................QENIRSSMLEEFFCHLFSD...LI.EK..SL.....ETipTN..LFIGK.A.NSYVDLTFSpSSFKDIFVSPNPYIHTKDQDFVLGV..KL..DLQIT......STEK..............-.....--.-TY.K.ESI.IIPALAVECKTYIERNMLDSCAGTARRLKSAMPYCIYIVAAEY..MKLK..DEQPEL....SDINEIYILCKA..SN.AD---RLKYKAEK------------KSPHPIDELLIIDFFDKVKGHLNS.IWWSP.DK.ALETG--kv.......................................
S2W195_9ACTO/113-332                 .........................................................................QLKLDNSILEEWFPWLVDP...RI.MP..EL.....EG..ID..LQVGP.A.KAFAAAHFQ.SVLTDVSGRPGLIVRSKDQDFTIGR..QT..YLRAS......FDKA..............F.....RNdHTD.D.SET.YIAYVAAELKTNLDKTMFQEATATSHDLRIAAPGSHYFLICEF..LDMT..PISSAG....TDIDEVLVLR-G..RR.VGSQNRKNFSNAVYRRDHREEHLRRVRSTPVRIDVVQRFVNHVREILQN.QRGDL.SG.AVERGYF.........................................
A0A433MWJ7_CHLFR/189-322             .................................................................stysevtv-------------------...--.--..--.....--..--..-----.-.---------.-------------------------..--..-----......----..............-.....TG.NTE.T.HIF.DIPVVAIECKTYLDKTMLEGSSRAAEDLKARNPNSLYLVVMEW..VKLT.sDVNLRK....YKVDQIYVLRQQ..KN.TDREFR---------------YELTYVKNPINPIVVQHLFKKVRNHLIM.DWTGG.IEhGIQRGWL.........................................
A0A6P1AST7_9BACT/92-310              .........................................................................QLKLDNTIIEEFLPRLGHP...SV.IP..EV.....AN..LD..VTLGP.K.KCFSSIYFE.SSLDSPAIGGGLRVRSKDQDFSISK..RL..FLKTS......HKED..............F.....SE.SL-.D.TET.YLSYVSAECKTNLDKTMFQEGCATAHDTKVAVPGSKYFLLCEW..LDMT..PLSTAP....TDIDEILLLRKA..KR.INSNVRKSYSSRQGRVANRESYVKYLVDNPFREDVFGRFVDHIRKLIQN.EVPVE.HN.VMELGYF.........................................
A0A261KNK8_9CYAN/87-303              .........................................................................QLKLDNTILEEFLPQLVFR...SL.-R..GI.....DE..-S..FELGP.R.NTFSGLSFL.SSLGNPGLDGKPSIRSKDKDFILGK..KL..YLKTS......LYPN..............F.....QD.YK-.L.IES.HLGYVCAECKTNLDKTMFQEAVATSRDLKIAVPGSLYFLICEF..LDMT..PISIVS....TQLDDVLIVRKS..KR.LSANIRQEHKTPEARRIHRQEYAEFLDTPKYYPDVFQRMIDKIKPLIDN.ANPSI.NK.VLNQGY-v........................................
A0A1D2PBN9_9CYAN/92-196              .........................................................................RSNLHSSVLEEFLYYLF-R...DL.AR..DF.....GE..NA..-LIGK.S.HTFKDIFFVpPKYSEMLKRPYARIEKKDHDFVIGA..TI..QASLE......AAPP..............-.....--.---.-.---.-------------------------------------------..----..------....------------..--.-------------------------------------------------.-----.--.-------peqdenpgemltllkeepgtysevtv...............
A0A421DLN9_9GAMM/91-294              .........................................................................RSNLHSSVLEEFMYYLF-K...DI.VE..EI.....SP..HA..-LIGK.S.HSFKDIFFRsSSYENMVERPYAIIEKKDHDFSIGI..SV..NAKMS......CNGS..............-.....-D.VDE.D.HIW.DIPAIAIECKTYLDKTMLQDVSTAAEEIKLKNPNAMYIVVAEW..LKLT.eNINLNK....YKVDQIYVLRKQ..KN.TDREYR---------------YLEGYVKNPIYDDAVMHLFSLVKNFLTS.DWEGG.INyGLQNGYL.........................................
#=GC seq_cons                        .........................................................................p.pLcsollEEFh.hLh.p...sl.....th.....sp...s....lG..t.psFtslhF..sshtphhtts.h.lcpKDpDFsIuh..pl...hphp......ht.......................t.th..p.hth.plshluhECKT.LDKTMhptssssAcclKttsPsuhYhllsEa..lcho..slshth....hplDplhlLRKt..Kp.hspphR...................h.tp.h...lh.+hhpplpthlt..p..t...p.slp.G.h.........................................
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