#=GF ID RecD_N
#=GF AC PF21185.1
#=GF DE RecBCD enzyme subunit RecD, N-terminal domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE ECOD:EF17572
#=GF GA 27.00 27.00;
#=GF TC 27.00 27.00;
#=GF NC 26.90 26.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF CL CL0123
#=GF RC Paper describing PDB structure 1w36
#=GF RN [1]
#=GF RM 15538360
#=GF RT Crystal structure of RecBCD enzyme reveals a machine for
#=GF RT processing DNA breaks.
#=GF RA Singleton MR, Dillingham MS, Gaudier M, Kowalczykowski SC,
#=GF RA Wigley DB;
#=GF RL Nature. 2004;432:187-193.
#=GF RC Paper describing PDB structure 3k70
#=GF RN [2]
#=GF RM 18668125
#=GF RT DNA binding to RecD: role of the 1B domain in SF1B helicase
#=GF RT activity.
#=GF RA Saikrishnan K, Griffiths SP, Cook N, Court R, Wigley DB;
#=GF RL EMBO J. 2008;27:2222-2229.
#=GF RC Paper describing PDB structure 5ld2
#=GF RN [3]
#=GF RM 27644322
#=GF RT Mechanism for nuclease regulation in RecBCD.
#=GF RA Wilkinson M, Chaban Y, Wigley DB;
#=GF RL Elife. 2016; [Epub ahead of print]
#=GF RC Paper describing PDB structure 5mbv
#=GF RN [4]
#=GF RM 28009252
#=GF RT Structural basis for the inhibition of RecBCD by Gam and its
#=GF RT synergistic antibacterial effect with quinolones.
#=GF RA Wilkinson M, Troman L, Wan Nur Ismah WA, Chaban Y, Avison MB,
#=GF RA Dillingham MS, Wigley DB;
#=GF RL Elife. 2016; [Epub ahead of print]
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found in RecBCD enzyme subunit RecD from
#=GF CC Escherichia coli and in similar proteins mostly found in
#=GF CC Gammaproteobacteria. RecD is a 5'-3' helicase that comprises
#=GF CC three domains. This entry represents the N-terminal domain of
#=GF CC RecD, which forms the principal interface between RecD and
#=GF CC domain 2B of RecC and leads to the conformational change in RecD
#=GF CC that has significant effects on the conformation of the RecC
#=GF CC subunit [1-4].
#=GF SQ 742
#=GS A0A0L0MEV9_9BURK/30-153 AC A0A0L0MEV9.1
#=GS A0A410UGC6_9GAMM/23-125 AC A0A410UGC6.1
#=GS A0A2U8I508_9GAMM/5-39 AC A0A2U8I508.1
#=GS A0A3N7CSZ2_9BURK/9-126 AC A0A3N7CSZ2.1
#=GS A0A251X5A3_9GAMM/4-110 AC A0A251X5A3.1
#=GS E0SCN3_DICD3/13-131 AC E0SCN3.1
#=GS A0A1H3F217_ALLWA/11-144 AC A0A1H3F217.1
#=GS A0A1Y0CV64_9GAMM/28-150 AC A0A1Y0CV64.1
#=GS RECD_ECOLI/7-108 AC P04993.2
#=GS F5T385_9GAMM/4-104 AC F5T385.1
#=GS A0A0B8PYW4_9VIBR/30-139 AC A0A0B8PYW4.1
#=GS A0A7Z0VP94_9GAMM/8-111 AC A0A7Z0VP94.1
#=GS R9PMD6_AGAAL/18-121 AC R9PMD6.1
#=GS A0A1G6LQH9_9BURK/31-154 AC A0A1G6LQH9.1
#=GS A0A1S2TXS8_9GAMM/12-115 AC A0A1S2TXS8.1
#=GS A0A1W1HBI2_9DELT/77-184 AC A0A1W1HBI2.1
#=GS A0A0Q4NLD6_9GAMM/7-112 AC A0A0Q4NLD6.1
#=GS A0A519ZLZ4_9BURK/20-137 AC A0A519ZLZ4.1
#=GS A0A510X349_9GAMM/26-141 AC A0A510X349.1
#=GS A0A1H6CU16_9GAMM/27-147 AC A0A1H6CU16.1
#=GS A0A369UIL0_9GAMM/11-117 AC A0A369UIL0.1
#=GS A0A0N1L0V3_9PROT/11-131 AC A0A0N1L0V3.1
#=GS A0A2I0CRF1_9PSED/25-138 AC A0A2I0CRF1.1
#=GS A0A401FYM6_9DELT/6-110 AC A0A401FYM6.1
#=GS A0A7W3IUR5_9ACTN/21-130 AC A0A7W3IUR5.1
#=GS A0A3S2UPJ5_9BURK/10-123 AC A0A3S2UPJ5.1
#=GS G2E1S3_9GAMM/20-130 AC G2E1S3.1
#=GS A0A370DMV0_9GAMM/8-112 AC A0A370DMV0.1
#=GS M4R6R5_BIBTR/5-126 AC M4R6R5.1
#=GS A0A1W1XCS0_9DELT/11-129 AC A0A1W1XCS0.1
#=GS A0A4R2F836_9GAMM/18-138 AC A0A4R2F836.1
#=GS A0A0N0ZBP2_9GAMM/6-115 AC A0A0N0ZBP2.1
#=GS A0A521AGM4_9BACT/9-112 AC A0A521AGM4.1
#=GS A0A556AZ40_9BURK/14-133 AC A0A556AZ40.1
#=GS A0A0S2KBN9_9GAMM/16-137 AC A0A0S2KBN9.1
#=GS A0A0Q2SFE9_VIBFU/15-132 AC A0A0Q2SFE9.1
#=GS A0A3N4B3X6_YERPE/5-112 AC A0A3N4B3X6.1
#=GS A0A0J8YQT1_9GAMM/8-116 AC A0A0J8YQT1.1
#=GS A0A2N0X3S7_9GAMM/20-135 AC A0A2N0X3S7.1
#=GS A0A1R4I628_9GAMM/46-166 AC A0A1R4I628.1
#=GS A0A0A1YNW4_9PSED/19-99 AC A0A0A1YNW4.1
#=GS A0A1B9QV19_9VIBR/9-134 AC A0A1B9QV19.1
#=GS A0A1G5IFK1_9DELT/13-110 AC A0A1G5IFK1.1
#=GS J2X5N0_KLEPN/7-112 AC J2X5N0.1
#=GS A0A4R1G5N3_9PAST/5-127 AC A0A4R1G5N3.1
#=GS A0A085G471_9ENTR/7-112 AC A0A085G471.1
#=GS A0A1M5LS59_9BURK/15-128 AC A0A1M5LS59.1
#=GS A0A848FG17_9BURK/30-154 AC A0A848FG17.1
#=GS C4ZM85_THASP/31-142 AC C4ZM85.1
#=GS I4VME0_9GAMM/10-116 AC I4VME0.1
#=GS Q1QYD2_CHRSD/25-144 AC Q1QYD2.1
#=GS A0A5M8FTD5_9GAMM/33-141 AC A0A5M8FTD5.1
#=GS R8AN63_PLESH/5-113 AC R8AN63.1
#=GS I4W827_9GAMM/19-123 AC I4W827.1
#=GS A0A2N7QRS8_9GAMM/10-118 AC A0A2N7QRS8.1
#=GS A0A095TER5_9GAMM/8-116 AC A0A095TER5.1
#=GS A0A7T0JSE8_9GAMM/10-129 AC A0A7T0JSE8.1
#=GS B7VJZ4_VIBA3/30-146 AC B7VJZ4.1
#=GS A0A1K1YNU1_9GAMM/16-138 AC A0A1K1YNU1.1
#=GS A0A2N7TL60_9GAMM/35-149 AC A0A2N7TL60.1
#=GS A0A1R4AZU9_9VIBR/9-121 AC A0A1R4AZU9.1
#=GS K9DAV7_9BURK/16-130 AC K9DAV7.1
#=GS A0A421DQI4_9GAMM/5-112 AC A0A421DQI4.1
#=GS A0A0K2BM12_9GAMM/5-118 AC A0A0K2BM12.1
#=GS A0A7X5UE80_9GAMM/11-102 AC A0A7X5UE80.1
#=GS A0A4Q7LR29_9BURK/18-143 AC A0A4Q7LR29.1
#=GS M4U5Z1_9GAMM/5-115 AC M4U5Z1.1
#=GS A0A420XIC9_9PAST/5-126 AC A0A420XIC9.1
#=GS A0A1H1SP67_9PSED/27-147 AC A0A1H1SP67.1
#=GS W1N4C8_9GAMM/24-145 AC W1N4C8.1
#=GS F9UF31_9GAMM/21-140 AC F9UF31.1
#=GS A0A0J7JRU5_9BURK/30-152 AC A0A0J7JRU5.1
#=GS A0A368TWV0_9GAMM/23-142 AC A0A368TWV0.1
#=GS A0A0Q4XLF3_9BURK/22-143 AC A0A0Q4XLF3.1
#=GS A0A6I6EXE3_9GAMM/7-112 AC A0A6I6EXE3.1
#=GS J3VTR9_9ENTR/5-115 AC J3VTR9.1
#=GS A0A0U3B5I4_9ALTE/8-116 AC A0A0U3B5I4.1
#=GS A0A1I3FYP5_9PSED/19-99 AC A0A1I3FYP5.1
#=GS A0A086WEF8_9BURK/20-135 AC A0A086WEF8.1
#=GS A0A0K1JU28_9BURK/17-140 AC A0A0K1JU28.1
#=GS A0A1H6SJL9_9GAMM/28-154 AC A0A1H6SJL9.1
#=GS A0A2K8UGI4_9GAMM/27-135 AC A0A2K8UGI4.1
#=GS A0A3N9TYX4_9GAMM/47-163 AC A0A3N9TYX4.1
#=GS A0A1N7BSX4_9GAMM/16-125 AC A0A1N7BSX4.1
#=GS A0A0E3Y7F4_9ENTR/5-114 AC A0A0E3Y7F4.1
#=GS A0A7Y3X988_9GAMM/47-162 AC A0A7Y3X988.1
#=GS A0A1I1P7K2_9GAMM/15-138 AC A0A1I1P7K2.1
#=GS A0A2T5P9N8_9PSED/19-99 AC A0A2T5P9N8.1
#=GS A0A2T0VMD0_9GAMM/31-148 AC A0A2T0VMD0.1
#=GS A0A0L7T2Y3_9GAMM/8-113 AC A0A0L7T2Y3.1
#=GS E1VNR5_9GAMM/31-142 AC E1VNR5.1
#=GS A0A4R3YKA2_9GAMM/6-112 AC A0A4R3YKA2.1
#=GS A0A2U8FP21_9BURK/41-162 AC A0A2U8FP21.1
#=GS A0A2A3XK42_9GAMM/48-169 AC A0A2A3XK42.1
#=GS A0A3N1Y144_9GAMM/5-101 AC A0A3N1Y144.1
#=GS A0A318GY76_9BURK/77-194 AC A0A318GY76.1
#=GS A0A4Z0QK25_SALET/7-71 AC A0A4Z0QK25.1
#=GS A0A6I4V8A3_9GAMM/8-113 AC A0A6I4V8A3.1
#=GS A0A1V3TSS5_9PAST/5-128 AC A0A1V3TSS5.1
#=GS A0A6I4VCW0_9GAMM/8-113 AC A0A6I4VCW0.1
#=GS N2J3M0_9PSED/49-167 AC N2J3M0.1
#=GS A0A0X8HDC8_9GAMM/30-143 AC A0A0X8HDC8.1
#=GS A0A839T5T5_AZOMA/13-99 AC A0A839T5T5.1
#=GS A0A2S5KK69_9PROT/24-139 AC A0A2S5KK69.1
#=GS A0A451DLN7_9GAMM/7-112 AC A0A451DLN7.1
#=GS A0A4R3HWA2_PAULE/12-130 AC A0A4R3HWA2.1
#=GS A0A0M2VK33_9GAMM/7-122 AC A0A0M2VK33.1
#=GS A0A2N7UML2_9GAMM/35-153 AC A0A2N7UML2.1
#=GS A0A0J5P410_PLUGE/7-112 AC A0A0J5P410.1
#=GS A1WWI2_HALHL/14-132 AC A1WWI2.1
#=GS V5BGF2_9GAMM/11-130 AC V5BGF2.1
#=GS A0A315D5Q4_9BURK/37-157 AC A0A315D5Q4.1
#=GS A0A1I1EJG6_9GAMM/8-134 AC A0A1I1EJG6.1
#=GS L0M2I0_ENTBF/7-112 AC L0M2I0.1
#=GS U3U703_9GAMM/8-114 AC U3U703.1
#=GS A0A1A9F583_9GAMM/5-108 AC A0A1A9F583.1
#=GS A0A261QPR6_9GAMM/5-112 AC A0A261QPR6.1
#=GS A0A2I0FYP6_9GAMM/8-113 AC A0A2I0FYP6.1
#=GS A0A1V2ZWD0_9GAMM/18-134 AC A0A1V2ZWD0.1
#=GS A0A4Q9QZU5_9GAMM/23-140 AC A0A4Q9QZU5.1
#=GS A0A859PT10_9ENTR/13-130 AC A0A859PT10.1
#=GS A0A0A7EFK7_9GAMM/14-112 AC A0A0A7EFK7.1
#=GS A9MS90_SALAR/7-108 AC A9MS90.1
#=GS A0A0M9DW17_9DELT/8-112 AC A0A0M9DW17.1
#=GS A0A140E736_9GAMM/20-130 AC A0A140E736.1
#=GS A0A0X8X7A4_HALHR/18-148 AC A0A0X8X7A4.1
#=GS A0A845GT17_9BURK/13-128 AC A0A845GT17.1
#=GS A0A0M4D1U0_9DELT/7-111 AC A0A0M4D1U0.1
#=GS Q8KDI0_CHLTE/4-102 AC Q8KDI0.1
#=GS A0A090SR14_9VIBR/11-95 AC A0A090SR14.1
#=GS A0A1M5RB52_9GAMM/12-129 AC A0A1M5RB52.1
#=GS Q6LMZ5_PHOPR/11-123 AC Q6LMZ5.1
#=GS W0V596_9BURK/21-136 AC W0V596.1
#=GS L0DU14_THIND/20-137 AC L0DU14.1
#=GS W9V0M2_9GAMM/17-132 AC W9V0M2.1
#=GS Q8ZMB7_SALTY/7-108 AC Q8ZMB7.1
#=GS A0A240CBJ5_SERFI/5-112 AC A0A240CBJ5.1
#=GS I4MYB8_9PSED/34-154 AC I4MYB8.1
#=GS H2FWP2_OCESG/15-133 AC H2FWP2.1
#=GS A0A077LCP5_9PSED/34-154 AC A0A077LCP5.1
#=GS T1H9F6_RHOPR/267-374 AC T1H9F6.1
#=GS C5WCD9_9ENTR/9-114 AC C5WCD9.1
#=GS A0A7U3YNY8_DESPD/7-109 AC A0A7U3YNY8.1
#=GS A0A0A3ASH9_9PAST/5-126 AC A0A0A3ASH9.1
#=GS A0A7T5VCA6_9DELT/7-108 AC A0A7T5VCA6.1
#=GS A0A432ZFQ1_9GAMM/13-137 AC A0A432ZFQ1.1
#=GS A0A2G8EKN3_9GAMM/5-108 AC A0A2G8EKN3.1
#=GS S7TPE2_DESML/10-110 AC S7TPE2.1
#=GS B5JRL2_9GAMM/10-130 AC B5JRL2.1
#=GS A0A2I6S2X8_9RHOO/22-137 AC A0A2I6S2X8.1
#=GS W0E455_MARPU/12-132 AC W0E455.1
#=GS A0A0J1HJK2_9GAMM/5-113 AC A0A0J1HJK2.1
#=GS A0A385YVW6_9PSED/19-99 AC A0A385YVW6.1
#=GS A0A0M1JJH3_9GAMM/6-111 AC A0A0M1JJH3.1
#=GS A0A2N5Y170_9GAMM/51-170 AC A0A2N5Y170.1
#=GS Q32CA2_SHIDS/7-108 AC Q32CA2.1
#=GS A0A2P6AR11_9GAMM/10-121 AC A0A2P6AR11.1
#=GS A0A068QYY7_9GAMM/8-115 AC A0A068QYY7.1
#=GS A0A7U7ELV3_9PSED/13-99 AC A0A7U7ELV3.1
#=GS A0A845I199_9BURK/13-128 AC A0A845I199.1
#=GS X7E0H0_9GAMM/29-140 AC X7E0H0.1
#=GS A0A0F7K4F0_9GAMM/3-102 AC A0A0F7K4F0.1
#=GS A0A1H5XAE8_9RHOO/44-163 AC A0A1H5XAE8.1
#=GS A0A1C3YW84_9GAMM/6-115 AC A0A1C3YW84.1
#=GS A0A2I5TB62_SERS3/5-112 AC A0A2I5TB62.1
#=GS A0A5Q2KB50_9ENTR/7-107 AC A0A5Q2KB50.1
#=GS H9L3X8_VIBCL/10-126 AC H9L3X8.1
#=GS Q5QUQ9_IDILO/13-128 AC Q5QUQ9.1
#=GS A0A859QZT7_9ENTR/7-112 AC A0A859QZT7.1
#=GS A0A4Z0C1I3_9BURK/20-142 AC A0A4Z0C1I3.1
#=GS A0A1S9AMA2_9BURK/15-133 AC A0A1S9AMA2.1
#=GS Q8EF46_SHEON/38-143 AC Q8EF46.2
#=GS A0A8I0CUP8_9PSED/7-108 AC A0A8I0CUP8.1
#=GS H0J4P9_9GAMM/35-150 AC H0J4P9.1
#=GS A0A1I2SPE6_9GAMM/4-132 AC A0A1I2SPE6.1
#=GS Q12LP3_SHEDO/38-150 AC Q12LP3.1
#=GS A0A1N6X4U0_9GAMM/28-147 AC A0A1N6X4U0.1
#=GS A0A4P8YEP9_9ENTR/7-111 AC A0A4P8YEP9.1
#=GS A0A653K0B1_9BURK/24-152 AC A0A653K0B1.1
#=GS A0A1W6YVB5_9BORD/28-148 AC A0A1W6YVB5.1
#=GS A0A1G7SCS0_9GAMM/46-179 AC A0A1G7SCS0.1
#=GS A0A848HDR7_9BURK/15-129 AC A0A848HDR7.1
#=GS C1D6T5_LARHH/11-126 AC C1D6T5.1
#=GS A0A7X3MBD3_9GAMM/8-113 AC A0A7X3MBD3.1
#=GS A0A1Y0KXT4_9PSED/5-99 AC A0A1Y0KXT4.1
#=GS A0A6J5DGA7_9BURK/45-165 AC A0A6J5DGA7.1
#=GS A0A369KYN7_9GAMM/66-185 AC A0A369KYN7.1
#=GS A0A4R3MU64_9GAMM/14-136 AC A0A4R3MU64.1
#=GS A0A4P7J887_9ENTR/7-108 AC A0A4P7J887.1
#=GS A0A0L0AVT6_9ENTR/7-112 AC A0A0L0AVT6.1
#=GS A0A1I4IVZ2_9BURK/24-139 AC A0A1I4IVZ2.1
#=GS S3DL56_9GAMM/9-122 AC S3DL56.1
#=GS A0A0Q5Z1E2_9BURK/8-126 AC A0A0Q5Z1E2.1
#=GS A0A1P8R8Q8_9GAMM/5-128 AC A0A1P8R8Q8.1
#=GS Q7VNC7_HAEDU/6-127 AC Q7VNC7.1
#=GS A0A014NLG1_9BURK/35-152 AC A0A014NLG1.1
#=GS A0A7W8M8F3_9BURK/27-148 AC A0A7W8M8F3.1
#=GS A0A143WQM1_9ENTR/5-113 AC A0A143WQM1.1
#=GS A0A3P1SHS9_9GAMM/38-132 AC A0A3P1SHS9.1
#=GS A0A0B4XNI2_9GAMM/8-71 AC A0A0B4XNI2.1
#=GS L0H0A4_9GAMM/5-122 AC L0H0A4.1
#=GS I3CII0_9GAMM/5-113 AC I3CII0.1
#=GS A0A521AZT2_9BACT/4-109 AC A0A521AZT2.1
#=GS A0A0J1D9Q1_9BURK/18-132 AC A0A0J1D9Q1.1
#=GS A0A5C2HFP3_9GAMM/11-122 AC A0A5C2HFP3.1
#=GS A0A0A7S174_FRIPE/10-124 AC A0A0A7S174.1
#=GS A0A0Q5I9H4_9BURK/19-133 AC A0A0Q5I9H4.1
#=GS A0A5B8SRF4_9GAMM/17-135 AC A0A5B8SRF4.1
#=GS A0A014LZG1_9GAMM/8-112 AC A0A014LZG1.1
#=GS V4JN54_9GAMM/10-112 AC V4JN54.1
#=GS E1V6P0_HALED/24-145 AC E1V6P0.1
#=GS A0A024HML3_PSEKB/10-127 AC A0A024HML3.1
#=GS A0A136A660_9ALTE/18-128 AC A0A136A660.1
#=GS A0A1I4W6W0_9GAMM/8-112 AC A0A1I4W6W0.1
#=GS A0A0Q6WEL8_9BURK/25-139 AC A0A0Q6WEL8.1
#=GS A0A562ZJU4_9BURK/14-137 AC A0A562ZJU4.1
#=GS A0A0H2VYX3_SHIFL/7-108 AC A0A0H2VYX3.1
#=GS A0A0M1JBS6_9GAMM/1-102 AC A0A0M1JBS6.1
#=GS Q2LTC7_SYNAS/20-134 AC Q2LTC7.1
#=GS A0A1S1NY57_9GAMM/15-140 AC A0A1S1NY57.1
#=GS U3U5B4_9ENTR/8-113 AC U3U5B4.1
#=GS A0A5D3YNH9_9BACT/8-113 AC A0A5D3YNH9.1
#=GS G4E535_9GAMM/18-139 AC G4E535.1
#=GS A0A1E5CYU3_9VIBR/28-139 AC A0A1E5CYU3.1
#=GS A0A1B4VDA0_9GAMM/5-105 AC A0A1B4VDA0.1
#=GS A0A850QKE0_9BURK/15-127 AC A0A850QKE0.1
#=GS A0A3A3GJT8_9BURK/11-126 AC A0A3A3GJT8.1
#=GS A0A377Z851_KLEPO/7-92 AC A0A377Z851.1
#=GS A0A071M0G1_9ENTR/5-110 AC A0A071M0G1.1
#=GS A0A1J4QD19_9GAMM/21-140 AC A0A1J4QD19.1
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