GenomeNet

Database: Pfam
Entry: SNAD2
LinkDB: SNAD2
Original site: SNAD2 
#=GF ID   SNAD2
#=GF AC   PF18745.1
#=GF DE   Secreted Novel AID/APOBEC-like Deaminase 2
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   Iyer LM
#=GF GA   25.00 25.00;
#=GF TC   28.10 30.00;
#=GF NC   24.40 22.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   29555751
#=GF RT   Diversification of AID/APOBEC-like deaminases in metazoa:
#=GF RT   multiplicity of clades  and widespread roles in immunity.
#=GF RA   Krishnan A, Iyer LM, Holland SJ, Boehm T, Aravind L;
#=GF RL   Proc Natl Acad Sci U S A. 2018;115:E3201.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A family of secreted AID/APOBEC like deaminases found in
#=GF CC   ray-finned fishes [1].
#=GF SQ   5
#=GS A0A1L8HMK1_XENLA/1-184    AC A0A1L8HMK1.1
#=GS A0A0F8B9R8_LARCR/31-231   AC A0A0F8B9R8.1
#=GS A0A0F8CWF2_LARCR/121-322  AC A0A0F8CWF2.1
#=GS A0A1L8HVL8_XENLA/24-223   AC A0A1L8HVL8.1
#=GS A0A2D0STW0_ICTPU/24-227   AC A0A2D0STW0.1
A0A1L8HMK1_XENLA/1-184               ..........................................................gln---------------N..QYAYVALFTV..AQCRQLADADL..RDALRQEDAANLVMTVADQ.QIY..--..R..GTK..M.V.AASYLQIDNQH...--AVHAEARLLNG...EGNAPSPVQD.LIN.R..N..E.....DRGCVLFYTLNSPCTGLCVRIGGQYNILNKL.NVFDNINN...RALVYNDVY.....FADLTR-....K.EDIVWAAWAAVNARIGF...YRC....FN....N...R...CVRCFKNGT..QNSNC.........
A0A0F8B9R8_LARCR/31-231              .............................................................VKKTILKCEVYKGTRM..VAATVLRWPDvlDQCPN-EPVQW..DDVLKECRNIK-TWSHLDD.TLT..LL..K..DKG..R.K.KSRSEKRCFDTvkeGRADHAEYRTLQA...-------FNT.LVD.R..K..N.....KNDLLLFYVLASPCSQRCTGITKKWSILENI.KKIMKWKN...YALVFSNVF.....KPRDGTP...iP.EKDSRGALERLGESIGLkniFRC....DK....D...K...CTSCSSGNQ..VTREC.........
A0A0F8CWF2_LARCR/121-322             .............................................................VKRSILKCEKYKGTRV..VAATVLRWPNvlDQCPN-EPVQW..GDVLKKCGERSMTWAELNS.KLR..ML..D..NEG..E.T.KSEHKKQCHAAvweGRADHAEYRTLEV...-------LNT.LVN.Q..D..N.....MNDFLLFYVLASPCPNRCASESSCWSILESI.LLVKKWKN...YGLVFSNVF.....KPRNGDP...lP.EQSLCGALVRLGKSIGLsniFRC....NE....H...K...CTSCSSGDQ..VDRYC.........
A0A1L8HVL8_XENLA/24-223              .............................................................LFRATNYIHKTITRGInvQYSYVAVFTA..DQCINLNIEDL..MNALREENASVLVKMVKSK.KIY..--..E..GPR..M.V.AASYLRLDNGS...--AVHAEARLLNG...KGGAPSPVQN.LLN.I..N..Q.....DKGCVLFYTLNSPCTRYCAKVGGRYNILSRL.DIFNGIQN...RALVYNEVY.....HDEFDK-....N.ETDVWAAWAAINRRIDF...YRC....TN....N...Q...CYRCFEYNTgsRNTDC.........
A0A2D0STW0_ICTPU/24-227              .............................................................LYNIINFLRNNYGGDY..QYALGINVPP..RYCEQVAPLDPpdQNFLPSDNNAQRVKDDMAG.DDK..IY..K..GDQ..L.I.GARPKPIPHSQ...NNNYHSEYLLLINstsSKLEPKPLME.TLL.D..S..N.....PDGCAVFFTRNSPCVRTCSTPNGLYSIIPALrSQFQNHKG..lKAFVFNRVW.....PRDENDP....-.--AWRNNIKTINDIIPV...YRC....DG....-...N...CTLCVNNND..VDRCC.........
#=GC seq_cons                        .............................................................lh+sI.hhcphhGsch..QYAhVlpaPs..DQC.NlsPlDh..pDsL+c-ssushVhschss.clp..hh..+..Gcp..h.l.uAcac+lsaus...spAsHAEYRLLpu...pt.tPpPlps.LlN.c..s..N.....ccGClLFYTLNSPCoppCusluGpYSILssL.slFpsaKN...+ALVFNcVa.....+s-pscP....s.EpslpuAlsslNcpIGl...YRC....ss....s...+...CTpCsssNs..VsRsC.........
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