#=GF ID SOR
#=GF AC PF07682.17
#=GF DE Sulphur oxygenase reductase
#=GF AU Kletzin A;
#=GF AU Studholme DJ;0000-0002-3010-6637
#=GF SE [4]
#=GF GA 25.00 25.00;
#=GF TC 25.10 93.30;
#=GF NC 23.70 21.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 81514348 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF CL CL0032
#=GF RN [1]
#=GF RM 2493451
#=GF RT Coupled enzymatic production of sulfite, thiosulfate, and
#=GF RT hydrogen sulfide from sulfur: purification and properties of a
#=GF RT sulfur oxygenase reductase from the facultatively anaerobic
#=GF RT archaebacterium Desulfurolobus ambivalens.
#=GF RA Kletzin A;
#=GF RL J Bacteriol 1989;171:1638-1643.
#=GF RN [2]
#=GF RM 11111027
#=GF RT Cloning and heterologous expression of a sulfur
#=GF RT oxygenase/reductase gene from the thermoacidophilic archaeon
#=GF RT Acidianus sp. S5 in Escherichia coli.
#=GF RA He Z, Li Y, Zhou P, Liu S;
#=GF RL FEMS Microbiol Lett 2000;193:217-221.
#=GF RN [3]
#=GF RM 12664265
#=GF RT Purification and properties of the sulfur oxygenase/reductase
#=GF RT from the acidothermophilic archaeon, Acidianus strain S5.
#=GF RA Sun CW, Chen ZW, He ZG, Zhou PJ, Liu SJ;
#=GF RL Extremophiles 2003;7:131-134.
#=GF RN [4]
#=GF RM 15030315
#=GF RT The sulphur oxygenase reductase from Acidianus ambivalens is a
#=GF RT multimeric protein containing a low-potential mononuclear
#=GF RT non-haem iron centre.
#=GF RA Urich T, Bandeiras TM, Leal SS, Rachel R, Albrecht T, Zimmermann
#=GF RA P, Scholz C, Teixeira M, Gomes CM, Kletzin A;
#=GF RL Biochem J 2004; [Epub ahead of print]
#=GF DR INTERPRO; IPR011661;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC The sulphur oxygenase/reductase (SOR) of the thermo-acidophilic
#=GF CC archaeon Acidianus ambivalens is an unusual enzyme consisting of
#=GF CC 24 identical subunits arranged in a perfectly symmetrical hollow
#=GF CC sphere and containing a mononuclear non-heme iron centre
#=GF CC (personal communication: A. Kletzin). At 85 degrees C in vitro,
#=GF CC elemental sulphur is oxidised to sulphite, thiosulphate and
#=GF CC hydrogen sulphide with no external cofactors needed. The
#=GF CC proposed equation is: 4S + O2 + 4 H2O ---> 2 HSO3- + 2 H2S + 2
#=GF CC H+.
#=GF SQ 31
#=GS A0A2U9IE15_9CREN/3-303 AC A0A2U9IE15.1
#=GS A0A6F8ZDC7_9FIRM/3-301 AC A0A6F8ZDC7.1
#=GS A0A094JY80_9BACT/3-305 AC A0A094JY80.1
#=GS W7KXF0_9CREN/3-303 AC W7KXF0.1
#=GS G0JQP4_9PROT/4-306 AC G0JQP4.1
#=GS O66762_AQUAE/8-332 AC O66762.1
#=GS A0A1C2FZF0_9GAMM/15-316 AC A0A1C2FZF0.1
#=GS Q972K4_SULTO/3-303 AC Q972K4.1
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X M; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X W; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X G; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X S; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X P; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X R; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M35 A; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M35 F; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M35 D; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M35 E; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X O; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X V; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X H; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X F; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X U; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X N; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M35 C; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X X; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X A; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X J; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X K; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X Q; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M35 H; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X E; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X I; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X L; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X C; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X T; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M35 B; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X B; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M3X D; 3-303;
#=GS Q972K4_SULTO/3-303 DR PDB; 6M35 G; 3-303;
#=GS A0A2I1DKN4_9PROT/4-306 AC A0A2I1DKN4.1
#=GS A0A1A6C2F7_9GAMM/5-307 AC A0A1A6C2F7.1
#=GS S7U334_DESML/1-56 AC S7U334.1
#=GS A0A2U3D831_SULT2/3-301 AC A0A2U3D831.1
#=GS A0A7Y0L8X0_9FIRM/3-301 AC A0A7Y0L8X0.1
#=GS A0A1P8UIF1_9GAMM/5-307 AC A0A1P8UIF1.1
#=GS A0A6A9QK79_SULME/3-303 AC A0A6A9QK79.1
#=GS C7LRC9_DESBD/10-306 AC C7LRC9.1
#=GS A0A4R1F918_9GAMM/14-304 AC A0A4R1F918.1
#=GS A0A1W1WDM4_SULTA/3-301 AC A0A1W1WDM4.1
#=GS S0ATP9_FERAC/3-301 AC S0ATP9.1
#=GS W0DSE7_9GAMM/16-307 AC W0DSE7.1
#=GS G8TY32_SULAD/3-301 AC G8TY32.1
#=GS A0A2S3QF68_9FIRM/3-301 AC A0A2S3QF68.1
#=GS D0L035_HALNC/5-309 AC D0L035.1
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA P; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA T; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA R; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA Q; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA Z; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA Y; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA U; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA M; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA V; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA B; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA O; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA L; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA I; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA C; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA H; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA K; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA J; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA W; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA A; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA D; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA F; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA E; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA G; 5-309;
#=GS D0L035_HALNC/5-309 DR PDB; 6QPA N; 5-309;
#=GS A0A1W1WET7_SULTA/3-301 AC A0A1W1WET7.1
#=GS A0A6F8ZGR9_9FIRM/3-301 AC A0A6F8ZGR9.1
#=GS A0A656HKX2_THINJ/1-78 AC A0A656HKX2.1
#=GS A0A8G2FVL0_PICTO/3-301 AC A0A8G2FVL0.1
#=GS A0A2U9IPG6_9CREN/3-303 AC A0A2U9IPG6.1
#=GS A0A191ZEW9_9GAMM/5-309 AC A0A191ZEW9.1
#=GS A0A031LS77_9CREN/3-303 AC A0A031LS77.1
#=GS A0A0Q1B5C6_9ARCH/3-301 AC A0A0Q1B5C6.1
A0A2U9IE15_9CREN/3-303 .KPYIAINMADLKNEPKTFEMFSAVGPKVCMVTARHPGFVGFQNHVQIGVLPFGERFGGAKMDMTKE...S.............STVRVLQYTMWKDWKDHEEMHRQNWSYLFRLCYSCASQMVWGPWEPIYEIKYADMPINTEMTDFTAVVGKKFAEGKPLe..iPVISQPYGKRVVAFGEHTVIPGKEKQFEDAIIKTLEMFKR.APGFLGAMLLKEIGVSGIGSFQFGSKGFHQLLESPGSLE.PDPNNVMY.......QVPEAKPTPPQYIVHVEWANLDALQFGMGRVLLSPEYREVHD-EALDTLIY.GPYIRIINPVMEGTFWR......
A0A6F8ZDC7_9FIRM/3-301 .KPYIAVNEVRLVNGPESFRRFEIIGPKMCMATANHGGFVGFQNHFPIGVFPMGGRYGGAKLDMRES...L.............NPLPVRQYTFWKDWRDHDQMHVDNFDTIFRLCSGCLDLMIDGPWEPIYEIVSHDLPENIGLTDVPAKLGAAFMAGQAV....PSVALPYGQRVVATSDHTIIPGREQDFETAIEQLMQAFKE.APGFLGYMVLRQMGVSAIGSLQLKPAALHQALQTTGDYP.PRIKEGNF.......ATPEGKATPAQYVVHMEWADMNTAVMGISRVVINTRFRALHD-PVLDTLLK.GPYIQLWSPQMEDTSWR......
A0A094JY80_9BACT/3-305 n-PIIAINMSKVVNRPESYETMHKIGPKVCITTATHPGFLGFEQLLQTGIHPMAGRYGGGALDMHET...L.............NPLGMFQYTIWKDVKSHEEMHYEQFNTIYELCGHCLNMVVEGPWEPFYEIIASDLPPVIGMIDVPNKLGESFSQQKPI....SKVALAS-QRIILIGDHWIMDGHETAFEKGAEETLRWLNAkAPGMIGWMILKQIGVSAVGSFQLGPEGMIKA--TLGANP.PKY-NTNYgdk.pldKPPIPPQKPTQYFVHMEWESPEHAHQGLGKVLINYELRQIHNKGVLAHLAR.GPYYMLFQPMMEDGCWR......
W7KXF0_9CREN/3-303 r-PYVAINMADLKNEPKTFEMFASIGPKVCMVTARHPGFVGFQNHIQIGVVPFGQRYGGAKPDMTKE...S.............STVRVLQYTFWRHWKDHEEMHRQNWSYLFRLCYSCASQMVWGPWEPIYEIVYADMPINTEMTDFTAVVGKKFAEGKPLe..iPVISQPYGKRVVAFSEHSVIPGKEKQFEEAVVKTLKLLKK.APGFLGAMVLKEIGVSGIGSFQFGAKGFHELLESPGSIE.PDPNNVQY.......QVTEAKPTPQQYVVHVEWANADALQFGMGRVLLEPETRRTHD-EALDTLVY.GPYIRILSPVMEGTFWR......
G0JQP4_9PROT/4-306 n-PIIAINQAKIFNRPESHEIMMKVGPKVCITTANHPGFLGFEQLIQTGIHPMAGRYGGGSVDMRET...L.............NPIAMYQYTVWKDVHSHEEMHHDNFDTIYELCGSCLDMVIEGPWEVYYEIIKSDLPPIMGITDVPTILGDAFAKQQPV....PKVALAE-QRAITVGDHWVMKGHEQDFEVGVIKTLEWLKAsVPGMIGWMILKQTGASAIGSFQLDPEGMLKA--TLGANP.PKY-NTNYgsk.iptQPPIPAQTPAQYLIHMEWESPAHAHTGLGYVMVDYDLRQIHNNGVLQHLDK.GPYYMFFAPMMEQGMWR......
O66762_AQUAE/8-332 g-VAVAINKAKVNNTPRFQELMYQVGPKVCITTAMHEGFLGFHAFIQVGAHPLGGRFGAAKVINADS...LeaiqregltaikyNPLELWQYTVWEKWEDHEEMHYQQFDRIFELCVGCFTEVVEGPNEPIYVVREANMPPVIDFTDVPKVLGESMMQAMQGkggiPKVRLLT-QRIAVVGIHKVKEGMEEKFIEGAVETLELLNKySAGMIGWMILEKIGESPYGTFQIKPPEFWEVVASRGAVP.PKTRETIWgeygkpeFQLEPAGHPKEFIVHMEWSRPESAMFGPALTAVNPKIKKVHDEKVMTTLAHiPPYYKVFMPLMEDLIL-f.....
A0A1C2FZF0_9GAMM/15-316 n-PVIAINMARISNRPENHEIMHKVGPKVCITTATHPGFLGFDQLLQVGIHPMAGRYGGGALDMRET...L.............NPISMFQYTVWKDAKSHEEMHYLQFDTIYELCSHCLAMVVEGPWEPVYEIVASDLPPSIGLTDVPALMMARAASQQPV....PKVALPM--RTIAVGDHSVMHGHETDFEQGVRDTMAWLMGhAPGMLGWMLLKQIGVSAIGSFQLDPAGMTKA--TLGANP.PRY-ATNYgdk.pldHPPIPAATPAQYFVHMEWEAPELAHQGLGKVLVNVEARRIHDHGVLAHINR.GPYYMLFASMMEEGTWR......
Q972K4_SULTO/3-303 .KPYVAINMVEVRNDPKTLELFGKVGPKVCMVTARHPGFVGFQNHVQIGVVPLGTRWGGAKMEMSQE...M.............HSLMLMQYTFWKNWKDHEEMHKQNWANLFRLCLQCADQMIWGPYEPLYEIVYANMPLNTEMTDFTVMVGKKFAAGEAVs..iPPISQPYGKRVVAFGEHIVKEGLENQFEEYAIKTLEAFRS.APGFLGGMILKEIGVSPLGSLQLNAKGFHQILETANGMDvPEP-VTIY.......EAPEFRNRPQRYIVHTEWSDTNALMFGLGRVLIYPEVRQIHD-KVLDTLVY.GPYIRVLNPMMEGTYWR......
#=GR Q972K4_SULTO/3-303 SS .--EEEEEEEEEE-SHHHHHHHHHTHHHHHHHHTTSTTEEEEEEEEEEEE--TTTTTTT--SS-TTT...-.............SEEEEEEEEEESSHHHHHHHHHHTHHHHHHHHGGGTTTEEEEEE-EEEEEEEEE---B--TTSHHHHHHHHHHTT-GGG..----B--SSSSEEEEEEEEE-TT-HHHHHHHHHHHHHHGGG.STTEEEEEEEEEEEE-TTTTT---HHHHHHHHH-STTSS-------S-.......-GGGS--BSEEEEEEEEESSHHHHHHHHTHHHHSHHHHHHHH-HHHTTEEE.EEEEEEEEEEEEETTHH......
A0A2I1DKN4_9PROT/4-306 n-PIIAINQSKVANRPESYATMMKVGPKVCITTASHPGFLGFEQLLQTGIHPMAGRYGGGAVDMHET...L.............NPISMFQYTVWKDVKSHEEMHHENFKEIFELCGSCLDMVIEGPWEPYYEVVRSDLPLIMGMTDIPAALGQSFAEQKPV....PKVALSA-KRSIAIGDHWVMDGHEEDFEKGAIETLSWMKEnVPGMIGWMIMKQFGVSAIGSFQFDPKGMLKA--TLGANP.PEY-NTNYgsq.vpdKPLIPGQKPTQYLVHMEWESPEHAHMGIAHAMLDYELRQIHNEGVLAHLDK.GPYYMLFGPMMEQGQWR......
A0A1A6C2F7_9GAMM/5-307 n-PIIAINMSKVSNTPDSFDTMMKVGPKVCITTASHPGFLGFEQLIQTGIHPMAGRYGGGSVDMRET...L.............NPIGMYQYTVWQDVRSHEEMHHDNFKEIYELCGSCLDMVIEGPWEPYFEVVRSDLPQIVSMTDVPQALGNAFAKEEQV....PKVALAS-QRAVVVGDHWVMHGHETDFEKGAFQTLEWMKEnVPGMIGWMVLKQFGVSAIGSFQLDPEGMLKA--TLGANP.PDY-NTNYgda.ihdQPPIPPQTPTQYLVHMEWESPEHAHMGLGHAMVDYELRKIHNDGVLAHLDR.GPYYAFFAPMMEQGLWR......
S7U334_DESML/1-56 .--------------------------------------------------------------MENA...L.............NPVRSYQYIMWKRWQDHDEFHEQQFSRIFELCTSCLGMVVEGPWEPVYR-----------------------------....----------------------------------------.---------------------------------------.--------.......---------------------------------------------------.-----------------ah....
A0A2U3D831_SULT2/3-301 .NPYIAISKAKVVNAPESFAAFESVGPKVCMVTANHNGFLGFQNHVQVGVFPMGGRFGGAKMDMHHE...L.............NPIGIAQYTMWKRWEDHEEMHMEQFDSIFRLCSRCLGMVVEGPWEDVYEIVAHDMPENVGMTDVPAVLGASFMAGEEM....PPVSLPYGQRVIAAGEHAVIPGKEEEFEQAVGQVMKQFKK.APGFLGYMIMRQIGASAVGSFQLEPDGIHQALQTLGDNP.PSSRAGNF.......QLMQAEKKPTAYIVHMEWADMKSAMFGISRVVVNHKVKAIHD-KALATLVQ.GPYITLWNPLMEDTSWR......
A0A7Y0L8X0_9FIRM/3-301 t-PYIALNKARVYNAESSYEKFTTVGPKVCMVTANHEGFVGFQNHVQIGVFPMGGRYGGAKMDMHET...L.............NPIGLAQYTMWKHWEDHDAMHYDNFDAIFRLCSQCLDMVVEGPWEPIYEIVAHDLPENVAMTDVPASLGAAWATGQPM....PAVSLPYGQRIIAASEHTTVPGREQEFEQAIVDVMTAFKR.VPGFLGYMVLKQIGASAIGSLQLVPDGIHQALQTRGDYP.PRIKDGNF.......QTPQAHQTPQEYLVHMEWADMNSAMMGISRVVINHQMRRIHD-RVLATLLK.GPYVTLWNPLMEDTSWR......
A0A1P8UIF1_9GAMM/5-307 n-PIIAINQTRVANRPETYATMMKVGPKVCITTASHPGFLGFEQLIQTGIHPMAGRFGGGAVDMRKT...L.............NPMGMYQYTVWKDVHSHEEMHHDNFKEIYELCGACMDMVVEGPWEPYYEVIKSDLPQIMSMTDVPQILGDSFAKQEQV....PKVALSA-QRTVLIGDHWIMHGHEDDFEKGAIETLTWMKEnVPGMIGWMIMKQFGVSAIGSFQLDPEGALK--QTLGANP.PPY-NSNYgdk.vhdTPPIPPQTPTQYLVHMEWESPDHAHMGLAHAMVDYELRQIHNKGVLAHLDR.GPYYMIFAPMMEQGIWR......
A0A6A9QK79_SULME/3-303 .KPYVAINQVIVKNEPKTFEMFQSVGPKVCMTTARHKGFVGFQNHIEIGVVPMGTRYGAAKMDMLKE...S.............STMGLYQYTMWKDWKDHEEMHKQNWSSLFRLCYSCMSQVVWGPWEPLYEITMADMPLNTEMTDFTVMVGQKFASGDALs..lPPISQPYGKRVVTYGEHVVKEGMEKEFEETLSRLLPMFKR.APGFLGYMVLKEIGASPLGSLQLSAKSWHQMLESANGMD.VPDPNGNF.......SPEQARNKPQKYVVHMEWSNTDAAQFGLGRVFLSPEYREIHD-QIVDTLIY.GPYIRILNPVMEGSFWR......
C7LRC9_DESBD/10-306 p-IYVALNMSKVVNNEESFDLMHKVGPRVCITTATHPGFLGFMANIQTGILPLAGRYGGGSTHMENA...L.............NPVRNYQYTMWKHWKDHDEFHEKQFSRIFELCTSCLEMVVEGPWEPVYSVIHAKMPTVRSMGQIAD-LGKDFVQQKDF....--IRFATPQRCVAIGEHTVAPGKEKAFEKGAIETMEALSD.ATGFLGYMILKQIGVCALGSFMLDPTSMAETLQTLGANP.PKKPRPLF.......KTLDAMPRPPEYLIHSEWDATEMAQMGFAKVLVNHAIRKIHDDGVMAHLIR.GPYIMFFQPMMEEPGWR......
A0A4R1F918_9GAMM/14-304 p-LYVAINKVLVKNDPNLMRMMKQASAKMCLATSLTPGFSGFDLMKQVGSCPMGMRWGAS-SDMSDE...L.............SHIWIDQITYWDSWQAHEDFHETFEDVVVDTCARCGDVLLEGPEEPVYRVVKSDLPSLISMTQWLR---KSAEGKADG....--YAVDSGNSVTVMATHKIKPGAEAEFEEGEIATMEGLKA.TSGMVGYQILKRIGISTLGSGHATVESIMEDMKNSSGSK.LKRTAEVW.......EG---YTIPAEYLVMVEWDSLGAAQAGMPHVNVKPELLFQHGPKVLNNCLH.MPTVRMSDSMFREQ---snr...
A0A1W1WDM4_SULTA/3-301 r-PYIAINDAKVVNAESSFQAFQQVGPKVCMVTANHPGFVGFQNHVQIGVFPMGGRYGGAKMDMHEE...L.............NPIGIRQYTMWKRWEDHEEMHYQQFDSIFRLCSSCLGMVVEGPWEDVYEIVSSDLPEVIAMTDVPSKLGAAFMAGQQP....APVAMPYGQRVIAGSDHYIIPGREQEFETAITDLMKMFQK.APGFLGYMVLKQIGASAIGSFQLQPEGIHQALQTLGDNP.PKNKEGNF.......KLIEAKKTPTKYLVHMEWMDLNSAMFGISRVVINGRYRAQHD-KALATLVQ.GPYVTLWSPMMEDTSWR......
S0ATP9_FERAC/3-301 .KPYVAINEVEMLNNDTTMQMFQQVGPKVCQVTARHPGFVGFQNHMQFGIIPMGTRWGGGSMDMT-K...M.............DTMNVYQYTMWKSIKDHEDMHRENFSSIFRLCSSCLSQVVYGPWEPLYEIVDASMPLNTEMADFTTMFGKKFAAGDPAg..vPPISMPYGQRTIALSEHTVKKDKEKEFESTIVEVMKDFEK.APGFLGYMILKEVGVSAVGSFQLKSKGIHETLESGGEVP.TQQ-EGSF.......KPEEARPTPPEYKVHMEWASPNDAMFGIGRVLFAHPAREIHD-KVLDTLIR.GPYIRLLNPMMEGTTWR......
W0DSE7_9GAMM/16-307 p-LYVAINRVLVENNPNLMRMMRQASSEMCLATALTPGFRGFDLMRQTGSCPMGMRWGA-STDMAQE...L.............SHIWIDQFTYWDSLEAHEEFHETFEDVVVTACDKCGNVLLDGPEEPVYRIVKSQLPRLVSMNQFEQ----ARAEGRDI....GQLAVDSGQTVTVLATHIVRPGREGEFEEGEIRTLDLLRQ.SNGMIGYQILKRVGISTLGSGHATVESIMERMKGTPGAK.LERTAEVW.......---EGYTIPAEYVVMVEWESLHAAQRGMPHVNVKPDILFVHGPKVFNNCVR.MPTVRMAVSMFAEQTY-r.....
G8TY32_SULAD/3-301 v-PYIAVNKARVLNAPSSFETFTSVGPKVCMVTANHEGFVGFQNHVQVGVFPMGGRYGAAKMDMHEE...L.............NPIGIVQYTMWRHWEDHEAMHYENFDSIFRLCSQCLNMVVEGPWEPLYEIVAHDLPENVSMTDVPAALGAAWMAGQPV....PAVSLPYGQRIVAASDHTVIPGREKDFEQAIVDVMTAFKK.APGFLGYMVMKQIGASAIGAMQLTPQGIHQALQTRGDNP.PRDKEGNF.......QPMQAHSSPQEYVVHMEWADMNSAMMGISRVVVNHKMRMIHD-RVLETVLK.GPYVTLWNPIMEDTSWR......
A0A2S3QF68_9FIRM/3-301 r-PIVAINDAKIVNQPSSFNMFESVGPKVCMVTANHSGFVGFQNHVQIGVFPMGGRYGAAKMDMHAE...L.............NPLGIRQYTMWKNWQDHEEMHYEQFDSIFRLCANCLGMIIEGPWENLYEITSSDLPDNMAMTDVPSRLGAAFMAGQTP....DAVSMPYGQRVIAGSDHRIIPGREQEFETAIEDLMQMFKK.APGFLGYMVLKQIGASAIGSFQLNPEGLHQALQTTGEYP.PRNKEGNF.......QLLDAKATPTEYIVHMEWQDLNSAMMGISRVVINTKYRAQHD-RVLATLVQ.GPYVTLWNPLMEDTSWR......
D0L035_HALNC/5-309 n-PIIAINMAKIANKPDSYETMMKVGPKVCITTASHPGFLGFEQLLQTGIHPMAGRYGGGAVDMRET...L.............NPMGMFQYTVWKDVHSHEEMHHDNFKEIFELCSGCLGMVIEGPWEPYFEVVKSDLPQIMSMTDVPQVLGDSFAKQERV....PKVALSS-QRTVVIGDHWVMDGHEKAFEQGATETLEWMKAnVPGMVGWMIMKQFGVSAIGSFQLDPEGAMKAVSTLGANP.PEY-NTNYgnk.vhdKPPIPGQTPTQYLVHIEWESPEHAHQGLGHVMVDYELRQIHNNGVLAHLDK.GPYYMFFSPMMEQGLWR......
#=GR D0L035_HALNC/5-309 SS ---EEEEEEEEE--SHHHHHHHHHTHHHHHHHHTTSTTEEEEEEEEEEEE--TTTTTTT--S--TTT...-.............BSEEEEEEEEESSHHHHHHHHHHTHHHHHHHHHHHGGGEEEEEEEEEEEEEEEE---EE-GGGHHHHHHHHHHTT---....---EETT-SSEEEEEEEEE-TT-HHHHHHHHHHHHHHHHHHSTTEEEEEEEEEEEEETTTTT---HHHHHHHTSSSSSS-.--S--BTTBSS.--SS-SEE--BSEEEEEEEEESSHHHHHHHHTHHHHSHHHHHHHHHHTGGGEEE.EEEEEEEEEEEEEGGGG......
A0A1W1WET7_SULTA/3-301 .KPYIAINSAKVANHPDSFRLFESVGPKVCMVTANHSGFVGFQNHVQIGVFPMGGRYGGAEMDMRQT...L.............NPLGIRQYTMWKRWEDHEEMHVQQFDSIFRLCSSCLGMVIEGPWEPIYEIVSSDLPDNMALTDVPATLGSQFMAGQPV....PPVSMPYGQRVIAASEHTIIPGMENAFESAIEDLMQMFKK.APGFLGYMVLKQIGASAIGSLQLTPEGIHQALQTLGDYP.PRAQSGNF.......ETLQAAPTPKEYVVHMEWQDLATAQFGISRVVVNTRYRAQHD-KVLKTLIR.GPYVTLWSPMMEDTSWR......
A0A6F8ZGR9_9FIRM/3-301 .NPYIAVNTAKVCNRPESFEAFQRVGPKVCMVTANNSGFLGFQNHVQVGVFPMGGRYGGAQMDMHDK...L.............NPLGIMQYTMWKRWEDHEQMHVDQFDSIFRLCSQCLGMVVEGPWEPVYEIVAHKMPDTVGMTDVPAALGAAFAAGQPV....PPVALPYGQRIIAHSEHLIIPGLEKEFEDAIVPVMEAFEK.APGFLGYMVMKQIGASAIGSMQLVPEGLHQALQTLGDYP.PRVKEGNF.......QLVQAKSTPAEYVVHMEWADLNAAMFGISRVAINHEVRTLHD-RALKTVLR.GPYVTLWNPMMEDTSWR......
A0A656HKX2_THINJ/1-78 .--------------------MMKVVPKVCITTASHPGFLGFEQLLQIVIHPMAGRFGGGAMDMRNSdppL.............NPMGMYQYTVWKDVHSHEEMHQ--------------------------------------------------------....----------------------------------------.---------------------------------------.--------.......---------------------------------------------------.-----------------frrvqy
A0A8G2FVL0_PICTO/3-301 .KPYVAINIVEMLNNETTMNMFQQVGPKVCMVTARHPGFVGFQNHVQFGVIPLGTRYGGASMDMT-K...M.............STMNVYQYTMWKNIKDHEDMHRENFSSIFRLCSSCLSQVVYGPWEPLFEIVDADMPLNTDMMDFTVMFGKKFAAGDPSg..vPPISQPYGRRTIALSEHTVKKGMEKDFESNIVEVMKDFSN.APGFLGYMILKEVGVSAVGSFQLKSQGIHEALESNGEVP.QHQ-EGAF.......SYEEARPTPPEYFVHMEWATPQDAQFGIARVLFKHETRVLHD-KVLDTLIK.GPYIRLLNPMMEGTSWR......
A0A2U9IPG6_9CREN/3-303 .KPYVAINMALLRNEPKTFDMFGSIGPKVCMVTARHPGFVGFQNHIQVGVVPFGTRYGGAKPDMTKE...Q.............STVGVYQYTFWKDWKDHEEMHKQNWSYIFKLCYSCSSQIVWGPWEPLYEIVYANMPINTEMTDFTTVVGRKFAEGKPMe..iPPISQPFGKRSVAFAEHIVKPGKEKQFEDAIIKTLEMFKR.APGFLGAMVLKEIGVSPLGSLQFGAKAFHEALETDGSNV.PDPNNTVF.......EAPEAKPTPPNYIVHVEWSGPDALQFGMGRVLISPEYRAVHD-EALDTLIY.GPYIRILNPVMEGTFWR......
A0A191ZEW9_9GAMM/5-309 n-PIIAINMTKIANRPDSYETMMKVGPKVCITTASHPGFLGFEQMLQTGIHPMAGRYGGGAIDMRET...L.............NPMGMFQYTVWKDVRAHEEMHHDNFKEIFELCGSCLDMVIEGPWEPYFEVIQSDLPQIMSITDVPQVLGDSFAQQKQV....PKVALAS-QRAVVIGDHWVMHGHEEDFEKGAVETLQWMKEnVPGMIGWMVMKQFGVSAIGSFQLDPEGAMKAVSTLGANP.PEY-NTNYgne.ihdKPPIPGQTPVQYLVHIEWESPDHAHMGLGHAMVDYELRQIHNNGVLAHLDK.GPYYMIFAPMMEQGVWR......
A0A031LS77_9CREN/3-303 .KPYVAINMADLRNEPKTFEMFASVGPKVCMVTARHPGFVGFQNHIQIGVLPFGTRYGGAKMDMTKE...S.............STVRVLQYTFWKDWKDHEEMHRQNWSYLFRLCFSCASQMIWGPWEPLYEITYANMPINTEMTDFTEVVGRKFAEGKPMe..iPAISQPYGKRVVAYAEHTVKPGKEKQFEDAIIKTLEMFKR.APGFLGAMVLKEIGVSAIGSFQFGSKGLHELLETPGSLE.PDPNSTIF.......EPPEAKPTPPNYIVHVEWADQDALQFGMGRVLLSPEYRAIHD-QALDTLIY.GPYIRIINPIMEGTFWR......
A0A0Q1B5C6_9ARCH/3-301 .KPYVAINEVEMLNDETTMKMFQQVGPKVCQVTARHPGFVGFQNHMQFGIIPLGTRYGGGSMDMT-K...M.............STMNVYQYTMWKNIKDHEDMHRDNFTSIFRLCSACLSQVVYGPWEPLYEIVDANMPVNTEMTDFTVMFGKKFAAGDPSg..vPPISMPYGKRTIALSEHTVKKDMQKEFESNIMEVMKDFEH.APGFLGYMILKEIGVSAVGSFQLKAKGIHETLESNGEVP.-KDQEGAF.......KPEEAVPTPPEYRVHMEWSSPEDAMFGIGRVLFAHPARELHD-KVLDTLIR.GPYIRLLNPMMEGTTWR......
#=GC SS_cons ---EEEEEEEEEE-SHHHHHHHHHTHHHHHHHHTTSTTEEEEEEEEEEEE--TTTTTTT--SS-TTT...-.............CCEEEEEEEEESSHHHHHHHHHHTHHHHHHHHHHHCCCEEEEEEEEEEEEEEEE---EE-CCCHHHHHHHHHHTT-GGG...---EETTSSSEEEEEEEEE-TT-HHHHHHHHHHHHHHHHHHSTTEEEEEEEEEEEEETTTTT---HHHHHHHCCSSTTSS.--S--BTTBSS.--SSGCCC--BSEEEEEEEEESSHHHHHHHHTHHHHSHHHHHHHHHHCHCCEEE.EEEEEEEEEEEEECCHH......
#=GC seq_cons ..PYlAINhuclhNpPcoachhtpVGPKVChsTApHPGFlGFpshlQhGlhPMGGRYGGuphDMccp...L.............NPlslhQYThWKch+DHEEMHcppFspIFcLCuuCLshVlEGPWEPlYEIVtuDhP.shuMTDhsshlGppFAtupss....P.luhshGpRslAhu-HhVh.G+Ep-FEpuhhcshchh+c.APGhLGaMlLKpIGlSAlGSFQLsscGhtpslpThGssP.Pc..sssa.......ps.pstsTPspYlVHMEWts.psAhhGlu+VhlshchRtlHD.pVLssLl+.GPYlplhsPhMEss.WR......
//
