GenomeNet

Database: Pfam
Entry: T3SS_needle_F
LinkDB: T3SS_needle_F
Original site: T3SS_needle_F 
#=GF ID   T3SS_needle_F
#=GF AC   PF09392.9
#=GF DE   Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF
#=GF PI   MxiH;
#=GF AU   Mistry J
#=GF SE   pdb_2ca5
#=GF GA   29.40 29.40;
#=GF TC   29.40 29.40;
#=GF NC   29.10 29.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16888041
#=GF RT   Molecular model of a type III secretion system needle:
#=GF RT   Implications for host-cell sensing. 
#=GF RA   Deane JE, Roversi P, Cordes FS, Johnson S, Kenjale R, Daniell S,
#=GF RA   Booy F, Picking WD, Picking WL, Blocker AJ, Lea SM; 
#=GF RL   Proc Natl Acad Sci U S A. 2006;103:12529-12533.
#=GF RN   [2]
#=GF RM   18281060
#=GF RT   Structural characterization of the Yersinia pestis type III
#=GF RT   secretion system needle protein YscF in complex with its
#=GF RT   heterodimeric chaperone YscE/YscG.
#=GF RA   Sun P, Tropea JE, Austin BP, Cherry S, Waugh DS;
#=GF RL   J Mol Biol. 2008;377:819-830.
#=GF RN   [3]
#=GF RM   22844497
#=GF RT   The Pseudomonas aeruginosa type III secretion system has an
#=GF RT   exotoxin S/T/Y independent pathogenic role during acute lung
#=GF RT   infection.
#=GF RA   Galle M, Jin S, Bogaert P, Haegman M, Vandenabeele P, Beyaert R;
#=GF RL   PLoS One. 2012;7:e41547.
#=GF RN   [4]
#=GF RM   23390616
#=GF RT   Regulation of the Yersinia type III secretion system: traffic
#=GF RT   control.
#=GF RA   Dewoody RS, Merritt PM, Marketon MM;
#=GF RL   Front Cell Infect Microbiol. 2013;3:4.
#=GF DR   INTERPRO; IPR021123;
#=GF DR   TC; 3.A.6;
#=GF CC   Type III secretion systems are essential virulence determinants
#=GF CC   for many gram-negative bacterial pathogens.  MxiH is an
#=GF CC   extracellular alpha helical needle that is required for
#=GF CC   translocation of effector proteins into host cells [1].  Once
#=GF CC   inside, the effector proteins subvert normal cell function to
#=GF CC   aid infection. The needle protein F, polymerises to form a shaft
#=GF CC   [2,3,4].
#=GF SQ   94
#=GS A0A0F5JWJ2_9BURK/16-86   AC A0A0F5JWJ2.1
#=GS D2UDE3_XANAP/26-96       AC D2UDE3.1
#=GS D2TKD9_CITRI/3-71        AC D2TKD9.1
#=GS Q2NTF8_SODGM/3-71        AC Q2NTF8.1
#=GS C0AR75_9GAMM/13-83       AC C0AR75.1
#=GS A0A0X1T7T7_PSEAA/15-84   AC A0A0X1T7T7.1
#=GS F7T1J7_9BURK/14-87       AC F7T1J7.1
#=GS A0A0V2F4M9_SALNE/1-59    AC A0A0V2F4M9.1
#=GS Q84CT6_BORPT/14-87       AC Q84CT6.1
#=GS A0A0A7EK21_9GAMM/20-90   AC A0A0A7EK21.1
#=GS A0A081KBN4_9GAMM/21-89   AC A0A081KBN4.1
#=GS A0A097QK45_9VIBR/3-71    AC A0A097QK45.1
#=GS PRGI_SALTY/9-79          AC P41784.1
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ S; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 3ZQE B; 11-64;
#=GS PRGI_SALTY/9-79          DR PDB; 2MEX D; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ a; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ G; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ Q; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2MEX B; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ E; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ C; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ B; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ A; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ W; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ J; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ U; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2MEX A; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ Y; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2JOW A; 9-75;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ T; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 3ZQB B; 9-71;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ V; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ c; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ H; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2MEX C; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ N; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ K; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ b; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 3ZQE A; 9-78;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ F; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ L; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 3ZQB A; 9-78;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ P; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ Z; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2X9C A; 19-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2X9C B; 18-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ M; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ O; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ D; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2KV7 A; 12-82;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ R; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ I; 9-79;
#=GS PRGI_SALTY/9-79          DR PDB; 2LPZ X; 9-79;
#=GS G2J8Z2_9BURK/8-76        AC G2J8Z2.1
#=GS Q7NUW2_CHRVO/3-71        AC Q7NUW2.1
#=GS A0A014MES2_9GAMM/17-87   AC A0A014MES2.1
#=GS W0HZV6_9GAMM/41-111      AC W0HZV6.1
#=GS K8WT23_PRORE/32-102      AC K8WT23.1
#=GS G5LPC6_SALET/3-71        AC G5LPC6.1
#=GS B8DMT0_DESVM/11-82       AC B8DMT0.1
#=GS W8V366_YEREN/16-86       AC W8V366.1
#=GS A0A0N1J610_9PSED/14-83   AC A0A0N1J610.1
#=GS L8JG82_9GAMM/3-71        AC L8JG82.1
#=GS A0A0J1FP12_9BURK/5-73    AC A0A0J1FP12.1
#=GS A0A0D8CRY0_9GAMM/6-73    AC A0A0D8CRY0.1
#=GS Q79GP3_BORPE/14-87       AC Q79GP3.1
#=GS PSCF_PSEAE/13-85         AC P95434.3
#=GS PSCF_PSEAE/13-85         DR PDB; 2UWJ F; 55-85;
#=GS D2UGZ6_XANAP/20-92       AC D2UGZ6.1
#=GS V5UHY9_9BURK/3-71        AC V5UHY9.1
#=GS A9MFA1_SALAR/8-78        AC A9MFA1.1
#=GS A0A0T9LMI6_9GAMM/30-99   AC A0A0T9LMI6.1
#=GS A0A0T9K9Q6_9GAMM/16-86   AC A0A0T9K9Q6.1
#=GS E5Y9X2_BILWA/14-85       AC E5Y9X2.1
#=GS N9VHX4_9GAMM/3-72        AC N9VHX4.1
#=GS U3AKN6_9VIBR/13-83       AC U3AKN6.1
#=GS A0A0T9XNY9_SALET/9-79    AC A0A0T9XNY9.1
#=GS A0A0M2KBJ5_9GAMM/19-89   AC A0A0M2KBJ5.1
#=GS Q7N0U8_PHOLL/14-84       AC Q7N0U8.1
#=GS C4K8S3_HAMD5/3-71        AC C4K8S3.1
#=GS A0A0D8D5J5_9GAMM/27-95   AC A0A0D8D5J5.1
#=GS E8LIU0_9GAMM/6-81        AC E8LIU0.1
#=GS A0A0T9WCL0_SALET/3-71    AC A0A0T9WCL0.1
#=GS Q2SH70_HAHCH/5-73        AC Q2SH70.1
#=GS A0A085WVQ6_9DELT/4-73    AC A0A085WVQ6.1
#=GS Q326S0_SHIDS/12-82       AC Q326S0.1
#=GS A0A0R0D3R1_9GAMM/6-78    AC A0A0R0D3R1.1
#=GS A0A014NRT0_9GAMM/34-101  AC A0A014NRT0.1
#=GS C4S9D7_YERMO/35-101      AC C4S9D7.1
#=GS Q63K18_BURPS/18-88       AC Q63K18.1
#=GS Q63K18_BURPS/18-88       DR PDB; 2G0U A; 18-84;
#=GS C5B9Q0_EDWI9/3-72        AC C5B9Q0.1
#=GS O68691_YERPE/16-86       AC O68691.1
#=GS O68691_YERPE/16-86       DR PDB; 2P58 B; 50-86;
#=GS D0Z4V3_PHODD/12-82       AC D0Z4V3.1
#=GS A0A0J6NJY7_9NEIS/12-82   AC A0A0J6NJY7.1
#=GS A0A109RWC6_9BURK/20-90   AC A0A109RWC6.1
#=GS H9L4C5_SALTY/3-71        AC H9L4C5.1
#=GS W6M9T9_9GAMM/5-73        AC W6M9T9.1
#=GS Q72WH4_DESVH/10-81       AC Q72WH4.1
#=GS E3BLT1_9VIBR/16-86       AC E3BLT1.1
#=GS C4K5N4_HAMD5/47-117      AC C4K5N4.1
#=GS N9VDP5_9GAMM/17-87       AC N9VDP5.1
#=GS Q7NVC1_CHRVO/13-83       AC Q7NVC1.1
#=GS F8JFE6_HYPSM/4-72        AC F8JFE6.1
#=GS W0HWF7_9GAMM/14-84       AC W0HWF7.1
#=GS A9MEL2_SALAR/3-71        AC A9MEL2.1
#=GS H4F3L4_9RHIZ/42-107      AC H4F3L4.1
#=GS A0A085WVR1_9DELT/4-73    AC A0A085WVR1.1
#=GS G5LSR2_SALET/9-79        AC G5LSR2.1
#=GS B6WRK9_9DELT/22-93       AC B6WRK9.1
#=GS V5UFF2_9BURK/19-89       AC V5UFF2.1
#=GS Q2NVJ2_SODGM/14-84       AC Q2NVJ2.1
#=GS A0A0F5K6S2_9BURK/7-73    AC A0A0F5K6S2.1
#=GS A0A108U9U7_9GAMM/38-102  AC A0A108U9U7.1
#=GS A0A010STP5_PSEFL/15-84   AC A0A010STP5.1
#=GS A0A109JZY6_9BRAD/3-71    AC A0A109JZY6.1
#=GS W0HX95_9GAMM/3-71        AC W0HX95.1
#=GS W8VBG5_YEREN/3-71        AC W8VBG5.1
#=GS Q87P24_VIBPA/12-82       AC Q87P24.1
#=GS D4ZKL6_SHEVD/3-71        AC D4ZKL6.1
#=GS A0A0L7TGF3_9GAMM/15-85   AC A0A0L7TGF3.1
#=GS D4HX33_ERWAC/18-88       AC D4HX33.1
#=GS E3BEK2_9VIBR/3-71        AC E3BEK2.1
#=GS Q74XK4_YERPE/3-71        AC Q74XK4.1
#=GS A0A0X8GTH1_9BURK/21-91   AC A0A0X8GTH1.1
#=GS A0A081NBE9_9GAMM/16-84   AC A0A081NBE9.1
#=GS V2J981_9BURK/1-67        AC V2J981.1
#=GS T0QH52_PHOTE/14-84       AC T0QH52.1
#=GS F9T7C1_9VIBR/13-83       AC F9T7C1.1
#=GS B4EYE4_PROMH/13-83       AC B4EYE4.1
#=GS A8T5N5_9VIBR/17-87       AC A8T5N5.1
#=GS K8WJ04_PRORE/28-94       AC K8WJ04.1
#=GS A0A0L7T5N1_9GAMM/3-71    AC A0A0L7T5N1.1
#=GS K8WJX0_9GAMM/27-103      AC K8WJX0.1
#=GS A0A157NV47_9BORD/14-87   AC A0A157NV47.1
#=GS W8X1Y7_CASDE/14-87       AC W8X1Y7.1
A0A0F5JWJ2_9BURK/16-86              ...........i-VDIAKGFNAGVGSLSSDLDAALATLQS...DP...S...SPAALANYQAILSEYTMFRNAQSSAVKAMKDIDSDIASK-l.........
D2UDE3_XANAP/26-96                  ............IYDIAKGFQNGVGSLGSALTAAQQALEA...NP...S...DPAALASYQAVLSDYTIFRNAQSSAVKAMKDIDTTILGN-l.........
D2TKD9_CITRI/3-71                   ...........l-TQITEDMGNIADTLAEPVPKLLSNP--...DL..vN...DPQKMLQLSFSINQFSSYINLESGMIKTVKDLISTI----snr.......
Q2NTF8_SODGM/3-71                   ...........v-SQLINTLSMLAHKAGNDIEDKMTAD--...KL...T...NPGTLLQAQFALQQYSTFINYSSAILKTMKDMVGGIIAKI..........
C0AR75_9GAMM/13-83                  ............IKKIDDYFQDPVKNQSDALKSALDALKA...DT...S...NAAALADYQARLAEYNITRNAESTSIKVVKDLAMSIIGNM..........
A0A0X1T7T7_PSEAA/15-84              ........lgqq----AEAFEAGAKDLKDKLDAALKALEG...NA...S...DPSLLAKYQSAFSSYTVFRNAQTNTIKGFKDIDMSIIQ--s.........
F7T1J7_9BURK/14-87                  ...........f-NSVNNTIYDSIRSQESNLQTTLSNLRT...NAdgsV...SQADMLKMQQQVQQWTMLIEIQSTITKQIADSLKGVIQK-a.........
A0A0V2F4M9_SALNE/1-59               ...........m-----------AHQAGQAINDKMNGN--...DL...L...NPESMIKAQFALQQYSTFINYESSLIKMIKDMLSGIIAKI..........
Q84CT6_BORPT/14-87                  ...........m-QSVNQAVNTRLNAHERDLRSRLEALSArgdGA...V...STSDLLIVQQEMQSWVVMIDLQSTVVKQVADSLKGVIQK-a.........
A0A0A7EK21_9GAMM/20-90              ............LKTVSTELQEVADATAGTLDSALADLKN...DP...N...NPAMLANFQASVNEYSVVMSLVATVQKSIKDAMSTIVQKM..........
A0A081KBN4_9GAMM/21-89              ............FDKVSETFGSQAEALDAALKTRVANM--...DP...N...STKDMVEFQVEFNKYMIVEGLRSSIVKSIKDTIQSIIQK-l.........
A0A097QK45_9VIBR/3-71               ............LNAIINQLSQMSAQSAQDIKTKMAQA--...DP...N...NPDQMLQAQFSVQQYSNFLGYESALIKAVKDMVQGIIAKI..........
PRGI_SALTY/9-79                     ............LDDVSAKFDTGVDNLQTQVTEALDKLAA...KP...S...DPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNF..........
#=GR PRGI_SALTY/9-79          SS    ............HHHHHHHHHHHTHHHHHHHHHHHHHHHH...ST...T...-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT..........
G2J8Z2_9BURK/8-76                   ............IEQIMAKTNEQVEALTQKVQNLIDTG--...DL...S...NPAVMSQFQLFLGQLSVLSNLPSSIVKVYVDRCQSIIQRI..........
Q7NUW2_CHRVO/3-71                   ............IEAITSQLSQLVEQAGNEVQSKVTAA--...DL...N...DPARMLQAQFAIQQYSVFVSYESAIMRAVKDMLSGIIQKI..........
A0A014MES2_9GAMM/17-87              ............LDKAAGAFEKGATNLMQELQLAQTALEN...DP...S...NPSTLAAYQAKLQAYTLFRNAQTSVVKAYKDVGANIIQNF..........
W0HZV6_9GAMM/41-111                 ............IDNIAEGFDKGATKMMRQLEKARKKLSK...KP...D...NPSVLAEFQAKLSEYTLFRNAQSSTVKAFKDIDAAIIQNF..........
K8WT23_PRORE/32-102                 ........iyrt----SASISSKAKQFGDELNTILADKTL...EV...D...NPLVLAKITAMSGNYNMARQLQSNFMKSIKDTDQALIRN-v.........
G5LPC6_SALET/3-71                   ............IAQLVDMLSHMAHQAGQAINDKMNGN--...DL...L...NPESMIKAQFALQQYSTFINYESSLIKMIKDMLSGIIAKI..........
B8DMT0_DESVM/11-82                  .dlgsmfqtgvn----------SIGDKGKELQARMENLMS..qDQ...V...SPEDMMQIQFEMGQYNAALEALSSVTKSMTDMLKSL----sqr.......
W8V366_YEREN/16-86                  ............LDKVSAGFEAGAKSMMDELKDAQKALEK...DP...S...DPSVLANYQAKLQQYTLFRNAQTSTVKAYKDIGAAIIQNF..........
A0A0N1J610_9PSED/14-83              ........lgrq----AQAFESGAKELKDILDQTLEKLKD...DP...S...NPGLLAAYQTAFSSYTVFRNVQTNTTKGFKDIDMSTIQ--a.........
L8JG82_9GAMM/3-71                   ............FDTINQGLGKVMEAKDAELTRFSTEM--...DP...R...RPEDLLQFQKLVSEWSMVMGLQSATIKSVRDALQGIIQKM..........
A0A0J1FP12_9BURK/5-73               ............LEQIYSNLAQQVTVNGEQMSQSLQGA--...DM...T...DPAAMLEFQRMTMGYQTAIGTESAMIKMVKDMLSSIMQKI..........
A0A0D8CRY0_9GAMM/6-73               ........teai----TNS----MGKLFEEKDAKVRETSE..lDL...T...DTGNLLKFQQAIGEWGNATSLASTTMKSLSDAVSGVIQKM..........
Q79GP3_BORPE/14-87                  ...........m-QSVNQAVNTRLNAHERDLRSRLEALSArgdGA...V...STSDLLIVQQEMQSWVVMIDLQSTVVKQVADSLKGVIQK-a.........
PSCF_PSEAE/13-85                    ............LDTVANALKEQANAANKDVNDAIKALQGt.dNA...D...NPALLAELQHKINKWSVIYNINSTVTRALRDLMQGILQKI..........
#=GR PSCF_PSEAE/13-85         SS    ............XXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXX...X...XXXXXXXXX-S--TTGGGTT--HHHHHHHHHHHHHHHTT-..........
D2UGZ6_XANAP/20-92                  .....qhldmdl-QSAMRNLTDEMISARHRIDAFMQTP-A...DY...S...NPAALAAFQVEMANYTVNNALVSGVVKRL-----------aggvetlv..
V5UHY9_9BURK/3-71                   ...........v-EEVHRGMSEGVRRMSNEATQAVRTQ--...EV...N...DPRHMLDVQFRLQQYSTMVGLHSAAIKLIKDTLMGIIAKI..........
A9MFA1_SALAR/8-78                   ............LDEVSAKFDKGVDDLQEQVTKALDQLAA...KP...S...DPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNF..........
A0A0T9LMI6_9GAMM/30-99              ...........y--DIAGKFTEPTKNLMNKIEAAQKSAIE...DI...S...NPIKLIDYTLYLGQYSALRQAQSNVAKKLLDLTSGIIRNI..........
A0A0T9K9Q6_9GAMM/16-86              ...........l-SQKSASFDTGVTSLNEELEKALNSLKG...NP...S...DPMLLAQYQSRLSEYTLYRNAQSNVVKVYKDVGSAIITNF..........
E5Y9X2_BILWA/14-85                  ..vnelfnsgld----------SISSKGKDLQAKMTEMLG..kDE...V...SPEDMMALQFEVGQYNAMLESLSSVTKSMTDMMKSLAQR-t.........
N9VHX4_9GAMM/3-72                   ............IDAIVAQLGSQVSRTANDAQTAMASS--...DI..nN...DPQAMLRSQYAMQQYSVMIGYESSVMKAVKDMMMGIISKI..........
U3AKN6_9VIBR/13-83                  ............LDAVKDKLAQQAKEANEAVNTAIDNLSS...SA...D...DPSKLAELQHAINKWSVIYNIASTTTRSIKDVMQSILQKV..........
A0A0T9XNY9_SALET/9-79               ............LDDVSAKFDTGVDNLQTQVTEALDKLAA...KP...S...DPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNF..........
A0A0M2KBJ5_9GAMM/19-89              ...........l-DGTAGGFETGSTNLMTELEKAQQALQQ...DP...S...NPSTLATYQSKLSAYTLFRSAQTAVVKAYKDVGSNIIQNF..........
Q7N0U8_PHOLL/14-84                  ............FDKVADQLKEPANAANKDVDEAITALKG...GP...D...NPALLADLQHKINKWSVIYNINSTIIRAMKDLMQGILQKI..........
C4K8S3_HAMD5/3-71                   ............IESLINALSDKMSKVSQDLKAKVSST--...DL...N...NPGHMVKMQYSIQQYSNLVSIQSSLVRVFKDLFSSIISKI..........
A0A0D8D5J5_9GAMM/27-95              ............LADVSNSFNAVVDKKEEAIKKLQDEG--...DF...E...DTKTVLLMQQMMNEWSFTLGLSSSLTKTIADSLKGIVQKI..........
E8LIU0_9GAMM/6-81                   .ssfadmiktgm-----DNMSEKAE----QMKEKMANISSldsTE...D...QQAALLEMQFEMGQYNAVMELTANLVKSLSESIKSISQK-v.........
A0A0T9WCL0_SALET/3-71               ............IAQLVDMLSHMAHQAGQAINDKMNGN--...DL...L...NPESMIKAQFALQQYSTFINYESSLIKMIKDMLSGIIAKI..........
Q2SH70_HAHCH/5-73                   ............FDAINDAMGRQATLKEEELRSFANSM--...DP...N...NSSDLIKFQQKVQEWGLITNLQSTTIKSLKDTIASIVQKM..........
A0A085WVQ6_9DELT/4-73               .......lggvf-----NNFSGTINSNVGTMNSWIDNQ--...NI..pA...EQKNLLKVQSEMQRMQEMVQLATTMMKALHEMSKSVIQN-l.........
Q326S0_SHIDS/12-82                  ............LSSLSETFDDGTQTLQGELTLALEALAT...NP...S...NPQLLAEYQSKLSEYTLYRNAQSNTVKVIKDVDAAIIQN-y.........
A0A0R0D3R1_9GAMM/6-78               ...........l-SEHSKMFDDGVKHLKAEMTRIMAKLGEe.gNA...S...DPALLADYQAALSQYNMYRMLQSNSSKSLSDQSKSVIRN-l.........
A0A014NRT0_9GAMM/34-101             ...fnnlvtstf---------NKISETNAQYKDVINALSEt.pNF..tS...DPEKLAILQNYVGEYTNHISLVSALVRK------------svstie....
C4S9D7_YERMO/35-101                 .........gal-------LNGRVKELADELKTALSDKNN...EM...D...NPIVLAKISALNGHYNGARQAQSNIMKSVKDTSQAIIRNM..........
Q63K18_BURPS/18-88                  ..........lt--GIGRAFDDGVKDLNKQLQDAQANLTK...NP...S...DPTALANYQMIMSEYNLYRNAQSSAVKSMKDIDSSIVSNF..........
#=GR Q63K18_BURPS/18-88       SS    ..........HH--HHHGGG-TTTHHHHHHHHHHHHHHHH...ST...T...-HHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHTTS-XXXX..........
C5B9Q0_EDWI9/3-72                   ............IEDIVSQLDNQVSRISSDANSVITSG--...NV..nN...NPEAMLKAQFAMQQYSVMIGYQSSIMKTVKDMMMSIISKI..........
O68691_YERPE/16-86                  ............LDAVAQTLKKPADDANKAVNDSIAALKD...KP...D...NPALLADLQHSINKWSVIYNINSTIVRSMKDLMQGILQKF..........
#=GR O68691_YERPE/16-86       SS    ............XXXXXXXXXXXXXXXXXXXXXXXXXXXX...XX...X...XXX--HHHHHHHTTHHHHHT--HHHHHHHHHHHHHHHHT-..........
D0Z4V3_PHODD/12-82                  ............LDDVKTKLEEQAKAANEAVNKAIKNLET...NA...D...DPSKLAELQHTINKWSVIYNINATTTRAIKDVMQSILQKV..........
A0A0J6NJY7_9NEIS/12-82              ............LSDMSGEFDKGVADLQKDLKTALDDLNK...NP...S...NPKILADYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNF..........
A0A109RWC6_9BURK/20-90              ...........v-DTLSAGFNEGVQSLNKALSAATSGLQN...DP...T...DPSKLAKVQSALSEYTIYRNSQSNMSKAFKDIASSAAQN-l.........
H9L4C5_SALTY/3-71                   ............IAQLVDMLSHMAHQAGQAINDKMNGN--...DL...L...NPESMIKAQFALQQYSTFINYESSLIKMIKDMLSGIIAKI..........
W6M9T9_9GAMM/5-73                   ............ISTINSTLGSIVDQQNDRLGQLSSNL--...NP...D...NTADLLKFQAETNRFSVVVGLQSAAIKTIGDAARGIVQKI..........
Q72WH4_DESVH/10-81                  dlgkmfqtgvds-----------LGDKGKALQDKMGTLMQ..qEQ...V...SPEQMLQLQFEMGQYNATLEALSSVTKSMTDMLKSL----sqr.......
E3BLT1_9VIBR/16-86                  ............LDQIKDIFSGAANDASQDVNDKITALKN...KP...D...DPALLAELQHSINKWTVTFNLSATTTRAIKDVMQSILQKI..........
C4K5N4_HAMD5/47-117                 ..........ik--AHTDAFAQKIITSEAQYKTHLNALEK...AP...S...DPVALSNVQRSLSALQMMINAQTNAIKKFTDNAMAIINNF..........
N9VDP5_9GAMM/17-87                  ............LDSVAKALKDQANESNQAVNKAIEDMKA...NP...D...NPALLAELQHKINKWSVVFNINSTVTRAMKDLMQGILQKI..........
Q7NVC1_CHRVO/13-83                  ............LDGVSNQFDQGVQDLHGAVEQALKDLSA...TP...S...DPKLLAKYQSKLSEYNLYRNAQSNAVKAFKDIDAAIIQNF..........
F8JFE6_HYPSM/4-72                   ............ISSMTSSLGQATSKAESAMSDFASTM--...DT...T...NTGDLLQYQSLTQNWSVCVGLESGSMKNLGDSLKSLVQKI..........
W0HWF7_9GAMM/14-84                  ............IDDIAKDFDTGAQTMMQQLEEARAELAK...AP...D...NPSVLAEFQAKLSEYTLFRNAQSSTVKAFKDIGAAIIQNF..........
A9MEL2_SALAR/3-71                   ...........i-GQLVDMLSHMARQAGEAINDKMNGN--...DL...L...NPESMIKVQFALQQYSTFINYESSMIKMIKDMLSGIIAKI..........
H4F3L4_9RHIZ/42-107                 ..........rq-----TELQTQIAAIEKGIRDIEQNS--...NL...S...DTEKMFSMQMAMNSWSAVTNLRTNMLKDVADVLKTIARNI..........
A0A085WVR1_9DELT/4-73               .......lggvf-----NNFSGTINSNVGTMNSWIDNQ--...NI..pA...EQKNLLKVQAEMQRMQEMVQLATTMMKALHEMSKSVIQN-l.........
G5LSR2_SALET/9-79                   ............LDDVSAKFDTGVQDLQTQVTDALDKLAA...KP...S...DPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNF..........
B6WRK9_9DELT/22-93                  .....igqlfqn-------ATNGLSQDGQALQAKMDQISA...SG..eV...DQMQLLELQFAMGQYNAKLETISSVTKSIQDMLKSLAQR-t.........
V5UFF2_9BURK/19-89                  ............LEQMSSEFDDKVSDLQERLQEAMEALKK...DA...S...DAVTLAHYQSVLGDYTTMRSAQSAAVKSMKEIAQGSISKF..........
Q2NVJ2_SODGM/14-84                  ............IDDIAKDFDTGAQTMMEQLETARKALSD...AP...D...NPSVLAEFQAKLSEYTLFRNAQSSTVKTFKDIGAAIIQNF..........
A0A0F5K6S2_9BURK/7-73               ...........d--GIINSLGSTLTATEADMNTFITQP--...NL...-...STSQLLQFQGLIGKWSLMSNLSSTLIKNLYDAFGGIVQKM..........
A0A108U9U7_9GAMM/38-102             ...lyaiaeltg---------KLADKKADQMTKAIEGLPA...DA...-...KPSDMLKTQAEVSEFQLMMNTFTNVVKTLGDSL-------gq........
A0A010STP5_PSEFL/15-84              ........lgqq----AAAFELGAVNLKIALDKALEDLKG...DA...S...DPGKLAAYQTAFSSYTVFRNAQTNTIKGFKDIDMAIIQ--a.........
A0A109JZY6_9BRAD/3-71               ..........fg--SITSSIGQSVVQSERNVRERMATM--...NP...D...DTMDLIRFQLSMTKHTTLLNLNSTIIKAVHDALNGIIRNI..........
W0HX95_9GAMM/3-71                   ...........v-SQLINTLSLLAHKAGNDVEDKMTAD--...KL...T...DPASLLRAQFAVQQYSTFINYSSAILKTMKDMVGGIIAKI..........
W8VBG5_YEREN/3-71                   .........inv---LVDGLAQSINKIGQDFQSQMTSG--...NP...S...DPEHMLKMQFAMQQYSSYINFSSALMKGIKDMVSGIIAKI..........
Q87P24_VIBPA/12-82                  ............LDDVKTKLEQQAKDANKSVTDAIKNLET...NA...D...DPSKLAELQHAINKWSVVYNINATTTRAIKDVMQSILQKV..........
D4ZKL6_SHEVD/3-71                   ............LSAIVNQLSQLSTRSAQEVQAKMSAG--...DL...N...DPDKMIKAQFSMQQYSNFVSYESAMIKAVKDMIQGIISKI..........
A0A0L7TGF3_9GAMM/15-85              ...........l-TNLSGEFNEKVISLNKEVQEALDKLTG...DS...S...DPVILAKYQSLASDYQVYRQTQSGVVKSYKDVATSIIANF..........
D4HX33_ERWAC/18-88                  ............LDEVSQKFEAGAANMITELTKAEEALEK...DP...S...NPAVLASYQAKLQEYTLFRNAQTSTVKAYKDIGAAIIQNF..........
E3BEK2_9VIBR/3-71                   ............LNAVINQLSQMSAQSAQDIQTKMANA--...DP...N...NPEQMMQAQFAVQQYSNFMGYESALIKAVKDMVQGIIAKI..........
Q74XK4_YERPE/3-71                   ............ISSPMGQLTNDIQQARQAYQNQMAAV--...NI...N...DPEQMLTSQFTMNQYSAFLDFKSIEMKMINDIRNRILSRI..........
A0A0X8GTH1_9BURK/21-91              ...........v-DQLSGEFNTGVKDLNAALSSALKELTA...NP...T...DPSLLAKVQSSLSEYTIYRNAQSNASKAFKDIAAGTVQNF..........
A0A081NBE9_9GAMM/16-84              ............FDKIQSEFGTKANELDIALKNKVSTM--...DP...N...STKDMVEFQVDFNKYMIIEGLRSSIIKSIKDTIQSIIQK-l.........
V2J981_9BURK/1-67                   ........midg-------MDGPVASASFNMAEAVQRA-V...ST...G...ETTDFILAQKMTAAFTNMTALQSSIIKAMHDTIAGIIQKI..........
T0QH52_PHOTE/14-84                  ............LDKVAAQLKTQADTANSDVNDAIVELNK...GP...D...NPALLADLQHKINKWSVIYNINSTVTRSMKDLMQGILQKI..........
F9T7C1_9VIBR/13-83                  ............LDEVKSKLTSQATTANKNVTDAIANLSA...NA...D...DPSKLAELQHTINQWSVIYNINSTTTRAIKDVMQSILQKV..........
B4EYE4_PROMH/13-83                  ............ISKVDQYFHKPVKTQSYELSEALEALKA...DT...S...NAAALAEYQAKLAEYNITRNAQSTSIKVIKDLAMSIIGNM..........
A8T5N5_9VIBR/17-87                  ............LDEVKDKLQEQAKLANEAVNAAIDNLSE...NA...D...DPSKLAELQHTINKWSMIYNINATTTRAIKDVMQSILQKV..........
K8WJ04_PRORE/28-94                  ..dkvkelfaey--------SASTNQERTALMDSVNTI--...DP...S...NPVQLLQFQNRVGKYSLAMNMISTLT--------------hksvsaidtv
A0A0L7T5N1_9GAMM/3-71               ............IEAITNQLSQLVDKAGNEVQSKVTAA--...DF...N...DPAKMLQAQFAIQQYSTFVSYESAIMRAVKDMLAGIIQKI..........
K8WJX0_9GAMM/27-103                 ..nwgmmyrsts------SISARAKDLADELDKILKGTGEe.lEV...D...NPLVLAKITALSGNYNMARQLQSNLMKSIKDTAQTAIRNI..........
A0A157NV47_9BORD/14-87              ...........f-NNVNSTVYESIRTQETNLRQTLSTIST...DAdgnV...SQADMLAMQQQISQWTMMVEVQSTISKSISDSLKSVIQK-s.........
W8X1Y7_CASDE/14-87                  ...........f-NAVNNTIYSGIRAQENKLRDTLSTLQA...DA...DgniSQADLLMLQQQTQQWTMMIELQSTITKQISDSLKGIIQK-s.........
#=GC SS_cons                        ..........HHHHHHHHHHHCCTHHHHHHHHHHHHHHHH...ST...T...XHHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHHHTTT..........
#=GC seq_cons                       .............pplssthsptspphspplpsthssh.t...cs...s...sPstLhphQttlspYohhhshpSshlKshKDhhpuIIpph..........
//
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