GenomeNet

Database: Pfam
Entry: TSLP
LinkDB: TSLP
Original site: TSLP 
#=GF ID   TSLP
#=GF AC   PF15216.6
#=GF DE   Thymic stromal lymphopoietin
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF AU   Hetherington K;
#=GF SE   Jackhmmer:Q969D9
#=GF GA   27.00 27.00;
#=GF TC   31.30 31.00;
#=GF NC   22.40 20.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Thymic_stromal_lymphopoietin
#=GF DR   INTERPRO; IPR029189;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF SQ   43
#=GS A0A2I3G3I4_NOMLE/29-153   AC A0A2I3G3I4.1
#=GS A0A1U8CJH3_MESAU/204-289  AC A0A1U8CJH3.1
#=GS G5C625_HETGA/16-104       AC G5C625.1
#=GS A0A2K5I2V3_COLAP/29-153   AC A0A2K5I2V3.1
#=GS W5PLC5_SHEEP/19-53        AC W5PLC5.1
#=GS A0A1D5R7F4_MACMU/29-153   AC A0A1D5R7F4.1
#=GS A0A151PI77_ALLMI/26-141   AC A0A151PI77.1
#=GS M3YMJ4_MUSPF/142-230      AC M3YMJ4.1
#=GS A0A0G2JUJ3_RAT/18-134     AC A0A0G2JUJ3.1
#=GS F6XFR7_HORSE/18-61        AC F6XFR7.1
#=GS F7I7D5_CALJA/29-153       AC F7I7D5.1
#=GS A0A1U7TS45_TARSY/159-282  AC A0A1U7TS45.1
#=GS A0A1S3AAI6_ERIEU/84-195   AC A0A1S3AAI6.1
#=GS L8YGS5_TUPCH/5-129        AC L8YGS5.1
#=GS G3T4N6_LOXAF/1-55         AC G3T4N6.1
#=GS J9P5I8_CANLF/29-154       AC J9P5I8.1
#=GS L5KIR5_PTEAL/1-51         AC L5KIR5.1
#=GS S9XG25_CAMFR/74-121       AC S9XG25.1
#=GS G3VRS1_SARHA/1-118        AC G3VRS1.1
#=GS G1TYN9_RABIT/18-53        AC G1TYN9.1
#=GS F1RLI5_PIG/20-130         AC F1RLI5.3
#=GS A0A151PJ22_ALLMI/26-153   AC A0A151PJ22.1
#=GS F6RUN5_MACMU/1-57         AC F6RUN5.1
#=GS A0A0D9RR50_CHLSB/29-153   AC A0A0D9RR50.1
#=GS A0A1U8CJH3_MESAU/133-178  AC A0A1U8CJH3.1
#=GS G1M2E0_AILME/19-143       AC G1M2E0.1
#=GS A0A2K5NKS1_CERAT/29-153   AC A0A2K5NKS1.1
#=GS G7P819_MACFA/29-153       AC G7P819.1
#=GS A0A1A6GDR1_NEOLE/1-79     AC A0A1A6GDR1.1
#=GS A0A2K5NL60_CERAT/1-57     AC A0A2K5NL60.1
#=GS A0A0C4DG43_HUMAN/29-153   AC A0A0C4DG43.1
#=GS K7E5V9_MONDO/34-162       AC K7E5V9.1
#=GS A0A1S3AAI6_ERIEU/37-87    AC A0A1S3AAI6.1
#=GS M3WGC3_FELCA/29-146       AC M3WGC3.2
#=GS TSLP_MOUSE/20-137         AC Q9JIE6.1
#=GS TSLP_MOUSE/20-137         DR PDB; 4NN6 A; 22-137;
#=GS TSLP_MOUSE/20-137         DR PDB; 4NN5 A; 20-137;
#=GS TSLP_MOUSE/20-137         DR PDB; 4NN7 A; 20-137;
#=GS A0A2I3SAB3_PANTR/29-153   AC A0A2I3SAB3.1
#=GS A0A2I3RF09_PANTR/1-57     AC A0A2I3RF09.1
#=GS A0A2I2YQB0_GORGO/29-153   AC A0A2I2YQB0.1
#=GS A0A096MPL6_PAPAN/29-153   AC A0A096MPL6.2
#=GS A0A091DGU3_FUKDA/1-78     AC A0A091DGU3.1
#=GS L5MDT6_MYODS/1-105        AC L5MDT6.1
#=GS H2PG88_PONAB/29-153       AC H2PG88.1
#=GS TSLP_HUMAN/29-153         AC Q969D9.1
#=GS TSLP_HUMAN/29-153         DR PDB; 5J11 A; 29-153;
#=GS TSLP_HUMAN/29-153         DR PDB; 5J13 A; 29-153;
#=GS TSLP_HUMAN/29-153         DR PDB; 5J12 A; 29-153;
A0A2I3G3I4_NOMLE/29-153              ............YDFTNCDFEKIKAAYLSTISKD.LITYMSGT..KSTEF...NNT.VSC..SNRPHCLTEIQ.....SLTFNRTAGCV.SLAKEM...FAMKTKAALALWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLLGLWRRFSR.......
A0A1U8CJH3_MESAU/204-289             ......fsllpe----------------------.--------..-----...---.-LC..E-QTDCLMKIE.....HLTLNPVPGCP.SLPWET...FAFNTKATLLSQCPGYSETQRNS..TQEMKHEVK-----DICLNQTSQIRLLWSS---lih....
G5C625_HETGA/16-104                  ............YNFSNCDFKKVQKDYDNIIFHS.LNDYMNKT..KSTKF...NH-.VAC..YESDDCLTKIE.....RHTFNST-ICP.SLSEEL...FALRTKATFSRYCPGYFRVQV--..---------------------------------s......
A0A2K5I2V3_COLAP/29-153              ............YDFTNCDFEKIEADYLSTISKD.LITYMSGT..KSTDF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTPGCA.SLAKEM...FAMKTKATLALWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLLGLWRRFIR.......
W5PLC5_SHEEP/19-53                   ............YNFTDCDFKKIKESYRNIIYQE.LNNYTKGV..S----...---.---..-----------.....-----------.------...-----------------------..---------------------------------eetf...
A0A1D5R7F4_MACMU/29-153              ............YDFTNCDFEKIEADYLRTISKD.LITYMSGT..KSTDF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTPRCA.SLAKEM...FARKTKATLALWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLLGLWRRFIR.......
A0A151PI77_ALLMI/26-141              ...........h-NFSICKHGEIKDKYMFILMPD.LDTYP---..-GKKD...QDY.HDC..EVGNENLLR--.....-CIHNVTRRCI.CTQYKH...IWQDTRALLNENCKSYDPLQ--D..TGCLKPVARKRRASGSCNKELAELRSLWRSYM-n......
M3YMJ4_MUSPF/142-230                 ........vnla----------------------.--------..-----...---.--A..REQPDCLTKIE.....RITFYPTHGCT.SLAKEI...FAIGTNATLTLQCPGYSGMQTYN..TQAKKKRKKREVTTYKCREQVAYLMGLWRRFSR.......
A0A0G2JUJ3_RAT/18-134                ............YNFSNCNFEMILRIYHATIFRD.LLKDLNGI..---LF...DQI.EDC..DSRTACLLKID.....HHTFNPVPGCP.SLPEKA...FALKTKAALINYCPGYSETERNG..TLEMTREIR-----NICLNQTSQILGLWLS---ciq....
F6XFR7_HORSE/18-61                   ............YDFTDCNFAKIEEEYQNVIFLA.LKEYMNGI..KSTQF...NHT.VYC..GD---------.....-----------.------...-----------------------..---------------------------------r......
F7I7D5_CALJA/29-153                  ............YDFTNCDFTKIKKEYCRTILED.LLTYMIGT..KSTEF...NNT.IFC..NNRSHCLTEIQ.....RLTFDPTPGCA.ALAKEL...FAVRTNATLALWCPGYSETQINA..TQEMKKRKKRKVTTNKCLEQVSQLSGLWRRFIR.......
A0A1U7TS45_TARSY/159-282             ............YDFTNCDFKKITQDYT-LIYND.LNTYMNGT..KSTKF...NST.VPC..YNQSHCLAEIE.....RLTISPTHRCA.SLAKET...FALRTKATLTGYCPDYPGIQINN..ARVMKKTRKREVTTNTCLEQVSQLLGLWRRLLR.......
A0A1S3AAI6_ERIEU/84-195              sssavyflrrds----------------------.--------..KGIQG...KKM.LRCieTQPSECLTEIE.....LLTFNSKDGCPsSLAKST...FAKKIKASFTLHCPDYPGIQINNnwTVKKKNRRKREDKICECPALVSVLKELWYRFSR.......
L8YGS5_TUPCH/5-129                   ............YNFTNCDFTKIKEDYEKLIVGD.FQTYINGT..KSTQS...SNY.IFC..SNQSDCLAKIE.....SLTFGTHAGCG.SLSKEM...FACRTKATFAHRCPDYPRVKVNN..TQAMKKRKKREDTAKECLKHVLRLQGLWRRFTR.......
G3T4N6_LOXAF/1-55                    .......nfaag----------------------.--------..-----...---.---..REQSECLAEIV.....RRTFSPEPGCA.SLAKKA...FAVVTEAVLTRWCPYYSRSQV--..---------------------------------s......
J9P5I8_CANLF/29-154                  ............YNFIDCDFEKIRWKYQEVIYQA.LEKYMDGV.nRSTEF...SHP.VYC..AYPPDCLARIE.....RLTLHRIRGCA.SGAREA...FAEGTVAALAAECPGYAAAPINN..TQAKKKRKKRGVTTNKCREQVAHLIGLWRRFSR.......
L5KIR5_PTEAL/1-51                    ............----------------------.--------..-----...---.---..-----------.....-----------.------...--MKTNATLTLQCPGYSGIRINN..TQAMK---KREDTTNKCRDVVSNLIRLWARFTR.......
S9XG25_CAMFR/74-121                  ............YNFTDCDFEKIKETYQNVIYEV.LKEYIKGT..KSIRF...NRF.VYC..EDR--------.....-----------.------...-----------------------..---------------------------------vsda...
G3VRS1_SARHA/1-118                   ............----------MASDFENAIYNKkLESLYSES..PSSEN...SD-.LFC..ETKSGCLTVLE.....QLARNWSNNCS.SEMGETfddFVNRTRIALKNYCPGFQENQANN..IQTPEKNMEERIKIMTCSEIARNLLEIWREYWQ.......
G1TYN9_RABIT/18-53                   ...........h-SFTNCDFGKIRKKYEKIIYPA.LEKYMQGV.sKE---...---.---..-----------.....-----------.------...-----------------------..---------------------------------tfs....
F1RLI5_PIG/20-130                    ............YNFTDCDFERIQDIFEEVIHHE.LKTYINGV..-----...---.---..SEQPDCLTKIE.....LFTFKPVHGCT.SLAKEE...FAKRTKAAFALQCSGYSGIQINN..TQAMR---KREVKANKCLEQVSYLLELWRRFSR.......
A0A151PJ22_ALLMI/26-153              ...........h-NFSICKHGEIKDKYMFILMPD.LDTYP-GK..KDQDY...HDCeVGL..TDRDHIVSAYQnenllRCIHNVTRRCI.CTQYKH...IWQDTRALLNENCKSYDPLQ--D..TGCLKPVARKRRASGSCNKELAELRSLWRSYM-n......
F6RUN5_MACMU/1-57                    ............----------------------.--------..-----...---.---..-----------.....-----------.-----M...FARKTKATLALWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLLGLWRRFIR.......
A0A0D9RR50_CHLSB/29-153              ............YDFTNCDFEKIEADYLSTISKD.LITYMSGT..KSTYF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTPRCA.SLAKEM...FARKTKATLALWCPGYSETQINA..TQAMKKRRKTKVTTNKCLEQVSQLLGLWRRFIR.......
A0A1U8CJH3_MESAU/133-178             ............YNFSLCNFTEISNIYSEVIYHD.LAEYLNGS..---LF...DQY.ESC..DNS--------.....-----------.------...-----------------------..---------------------------------vskvv..
G1M2E0_AILME/19-143                  ............YNFTGCDFEKIRKKYQEVIYQA.LEKYMNGT..KSTEF...NNP.IYC..EDPPDCLAKIE.....RITFHPTHDCT.SLAEEI...FAIGTRATLTLQCPSYSGMQINN..TQAKKKRKKRKVTTNKCREQVAYLIGLWRRFSR.......
A0A2K5NKS1_CERAT/29-153              ............YDFTNCNFEKIEADYLSTISKD.LITYMSGT..KSTDF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTPRCA.SLAKEM...FARKTKATLALWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLLGLWRRFIR.......
G7P819_MACFA/29-153                  ............YDFTNCDFQKIEADYLRTISKD.LITYMSGT..KSTDF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTPRCA.SLAKEM...FARKTKATLALWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLLGLWRRFIR.......
A0A1A6GDR1_NEOLE/1-79                ...........m--------------YSEAIYPD.LKEYLNGVifNFWRFlcsLNS.AAC..E-QADCLMKIE.....YRTLNPIPGCP.SLPKEM...FALKTKGTLINQCPGYSET----..---------------------------------.......
A0A2K5NL60_CERAT/1-57                ............----------------------.--------..-----...---.---..-----------.....-----------.-----M...FARKTKATLALWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLLGLWRRFIR.......
A0A0C4DG43_HUMAN/29-153              ............YDFTNCDFEKIKAAYLSTISKD.LITYMSGT..KSTEF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTAGCA.SLAKEM...FAMKTKAALAIWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNR.......
K7E5V9_MONDO/34-162                  ............YNFSSCNHYQMASDYENIIYNEkLESLYNSE.mPSSED...SN-.LFC..ETKSDCLTVIE.....QLARNWSNNCS.SEMGETleaFVNRTRIALKSYCPVFQGNQTNN..MQTTKNNMEEGIKKMTCPEIARNLLDIWREYWK.......
A0A1S3AAI6_ERIEU/37-87               ............YDFNSCDFASIKMDYLRTISKE.LEKCVDED..TSAEL...DSH.LEC..EEK--------.....-----------.------...-----------------------..---------------------------------vsrsssa
M3WGC3_FELCA/29-146                  ............YNFTDCDFGKIRKKYQEVIYQA.LNKYMNGV..-----...NPV.SGC..S--PDCLAKID.....LITFYPTHGCT.TLAKEI...FAIRTNATLTLQCPGYSGTQINN..TQAKKKRKKRQVTTNKCREQVSHLMELWRRFSR.......
TSLP_MOUSE/20-137                    ............YNFSNCNFTSITKIYCNIIFHD.L----TGD.lKGAKF...EQI.EDC..ESKPACLLKIE.....YYTLNPIPGCP.SLPDKT...FARRTREALNDHCPGYPETERND.gTQEMAQEVQ-----NICLNQTSQILRLWYSFMQ.......
#=GR TSLP_MOUSE/20-137         SS    ............--GGGS-HHHHHHHHHHTHHHH.H----HHH.HTT---...--S.---..SSHHHHHHHHH.....HHHHS-BTTBT.TGGGSH...HHHHHHHHHHHHSTT--------.---------H-----HHHHHHHHHHHHHHHHHHH.......
A0A2I3SAB3_PANTR/29-153              ............YDFTNCDFEKIKAAYLSTISKD.LITYMSGT..KSTEF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTAGCA.SLAKEM...FAMKTKAALTIWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNR.......
A0A2I3RF09_PANTR/1-57                ............----------------------.--------..-----...---.---..-----------.....-----------.-----M...FAMKTKAALTIWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNR.......
A0A2I2YQB0_GORGO/29-153              ............YDFTNCDFEKIKAAYLSTISKD.LITYMSGT..KSTEF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTAGCA.SLAKEM...FAMKTKAALAIWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNR.......
A0A096MPL6_PAPAN/29-153              ............YDFTNCNFEKIEADYLSTISKD.LITYMSGT..KSTDF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTPRCA.SLAKEM...FARKTKATLALWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLLGLWRRFIR.......
A0A091DGU3_FUKDA/1-78                ...........m----------------------.--------..-----...---.---..-NKADCLAKIE.....RHTFSS-TTCP.SLSEEL...FALRTNATLARYCPGYFKVQINN..TQKVQRKVN-----RNCLEQTSQIIGWWRFFSR.......
L5MDT6_MYODS/1-105                   ...........m-------------DYLNIISKD.L-------..TCTDC...DAT.LRC..EDQPDCLTKIE.....RLTLHPTPGCK.SLPEE-...LASRTQATLERSCPGYYRKQKNN..AQAMKKRKKREDTIKGCQKIVSNLIGLWRRFMR.......
H2PG88_PONAB/29-153                  ............YDFTNCDFEKIKAAYLSTISKD.LITYMSGT..KSTEF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTAGCA.SLAKEV...FAMKTKAALALWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLLGLWRRFNR.......
TSLP_HUMAN/29-153                    ............YDFTNCDFEKIKAAYLSTISKD.LITYMSGT..KSTEF...NNT.VSC..SNRPHCLTEIQ.....SLTFNPTAGCA.SLAKEM...FAMKTKAALAIWCPGYSETQINA..TQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNR.......
#=GR TSLP_HUMAN/29-153         SS    ............--GGGS-HHHHHHHHHHTHHHH.HHHHHTTS..-GGGS...--S.---..SSHHHHHHHHH.....HHHHS-BSSB-.--TTSH...HHHHHHHHHHHHSTTSTTS----..------XXXXX---HHHHHHHHHHHHHHHHHT-.......
#=GC SS_cons                         ............--GGGS-HHHHHHHHHHTHHHH.HHHHHCCC.HTCGGS...--S.---..SSHHHHHHHHH.....HHHHS-BTTBT.TGCCSH...HHHHHHHHHHHHSTTSTTS----..------XXHXX---HHHHHHHHHHHHHHHHHCH.......
#=GC seq_cons                        ............YsFosCsFtcIpttY.phI.p-.L.pYhsGs..putph...sph.l.C..pspscCLscIp.....phThsss.tCs.SLscEh...FAh+T+AsLshhCPGYucsQlNs..TQshK+ctK+csssspCh-QVSpLhuLWRRF.R.......
//
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