GenomeNet

Database: Pfam
Entry: Tox-REase-9
LinkDB: Tox-REase-9
Original site: Tox-REase-9 
#=GF ID   Tox-REase-9
#=GF AC   PF15650.6
#=GF DE   Restriction endonuclease fold toxin 9
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   de Souza RF;0000-0002-5284-4630
#=GF AU   Anantharaman V;0000-0001-8395-0009
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   [1]
#=GF GA   27.30 27.30;
#=GF TC   27.90 31.30;
#=GF NC   26.00 27.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR028902;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A predicted toxin of the restriction endonuclease fold present
#=GF CC   in bacterial polymorphic toxin systems. In bacterial polymorphic
#=GF CC   toxin systems, the toxin is exported by the type 2 or type 7
#=GF CC   secretion system [1].
#=GF SQ   25
#=GS F9Z4D9_ODOSD/1467-1553      AC F9Z4D9.1
#=GS K9ER08_9BACE/161-252        AC K9ER08.1
#=GS A0A2E7P6I2_9BURK/149-235    AC A0A2E7P6I2.1
#=GS A0A1I3P1V1_9PLAN/2373-2457  AC A0A1I3P1V1.1
#=GS A0A1H4D5M5_9BACT/62-149     AC A0A1H4D5M5.1
#=GS A0A0F0GLE2_NOCAE/1010-1084  AC A0A0F0GLE2.1
#=GS A0A1Q2HTR7_9CORY/40-126     AC A0A1Q2HTR7.1
#=GS A0A1W1ZJG6_9FLAO/1149-1235  AC A0A1W1ZJG6.1
#=GS C5BI71_TERTT/1669-1752      AC C5BI71.1
#=GS B7GLX9_ANOFW/208-295        AC B7GLX9.1
#=GS A0A1I5Z4E8_9BACT/1-81       AC A0A1I5Z4E8.1
#=GS R5G6W7_9FIRM/1512-1589      AC R5G6W7.1
#=GS E3IWI9_FRAIE/3211-3306      AC E3IWI9.1
#=GS H1Z991_MYROD/1194-1282      AC H1Z991.1
#=GS F8KV49_PARAV/144-193        AC F8KV49.1
#=GS A0A037ZEC1_9RHOB/379-460    AC A0A037ZEC1.1
#=GS F8KV51_PARAV/1-49           AC F8KV51.1
#=GS Q5L196_GEOKA/2214-2301      AC Q5L196.1
#=GS A0A1H4D3T6_9BACT/31-108     AC A0A1H4D3T6.1
#=GS G8M231_CLOCD/2887-2974      AC G8M231.1
#=GS H8KTP5_SOLCM/1076-1163      AC H8KTP5.1
#=GS A0A1F5QCW2_9BACT/2668-2754  AC A0A1F5QCW2.1
#=GS A0A1T5M3S2_9MICO/1994-2079  AC A0A1T5M3S2.1
#=GS A0A0G3A7N4_9DELT/1-48       AC A0A0G3A7N4.1
#=GS A0A1I5G881_9ACTN/2218-2303  AC A0A1I5G881.1
F9Z4D9_ODOSD/1467-1553                 ...................FTKSSLKQGRQMHSLYK.----LG.ANGVKEYVLPS.K..R...RID..FLDIEN..KIIY...ELKPFNPRSIKRGIKQLHDYKRELKlv....pefKEY-..-TWTMILETY...........
K9ER08_9BACE/161-252                   ...................YTKSSLQLGQKMHSAYH.-----A.GQYGKEFVLPS.G..K...RID..YLDIQN..GIIY...ELKPYNPRSVKQGLRQLQMYLNELQtpaviqrhpEFKN..IQWKTVLDTY...........
A0A2E7P6I2_9BURK/149-235               .................ge--NPAARRGREAHENYE.--NALGdDGYEFNKALPS.G..N...RPD..ALNYTN..NPVR...ELKPDNPDAMRQGWRLLEKYAKELE.........ESTG..QLWNKVLNT-h..........
A0A1I3P1V1_9PLAN/2373-2457             .................ge--NSYAQRGRQAHQDWD.----PG.DGYQKGQLLPS.G..R...KPD..AVNFDT..CHIK...ELKPNNPKAIRKGEIQLQKYIDEYN........iRYPG..KNFTGCVETY...........
A0A1H4D5M5_9BACT/62-149                ................gst---VANRLGQQMHKAYK.AGDVLD.GVRIKEFMLPS.R..K...RID..FIDLEK..KIIY...ELKPNNPRAIKQGYKQLEMYKQEVE.........SIYG..KGFKTILDTY...........
A0A0F0GLE2_NOCAE/1010-1084             .........dqmprgldpe-----------------.------.----FELDLPD.GgtK...RLD..RVDWDN..RVIY...EIKPNNPVEIAKGQQQVKLYVHYMN.........QQTGlpGGWSGKVVTY...........
A0A1Q2HTR7_9CORY/40-126                .................ga--NSHAAYGNKMHKAYS.AE-KKA.AGYVTNSGLPD.S..RgrlRPD..AYKMNG..RYIAevrEYKPDSPSGLAHGRKQLRAYVD---.........----..----------ysekynraiaa
A0A1W1ZJG6_9FLAO/1149-1235             ...................YTKSSLKLGQQMHKSYK.----VG.ADGIKEFRLPS.G..K...RID..FLDINN..RTIY...ELKPFNPRAMQQGQKQLNMYMQELQt......mpQFKG..INWKTVLDTY...........
C5BI71_TERTT/1669-1752                 .................kv--AEAAAKGRQMHKDYD.----YG.PGFEKEVTLPS.G..K...RAD..AVNWET..REVV...ELKPNNPNAIRRGEKQVEGYRQELQ.........CTTG..ECWTSRVETY...........
B7GLX9_ANOFW/208-295                   ...................YTKSNLKLGRQMHKSYK.ANKVLK.GVREKEFRLPS.G..K...RID..FIDFEK..KIIY...ELKPNNPRAIKKGLKQLKAYKKEVE.........KIYG..KGWRTVLEVY...........
A0A1I5Z4E8_9BACT/1-81                  ...................-----------MHKAYH.-----A.GKVGKEFRLLS.G..R...RID..YLDMQN..GIIY...ELKPNNPRAILQGQKQLQMYLQELQspamlqkypQFKG..IQWKTVLDTY...........
R5G6W7_9FIRM/1512-1589                 ..................s-TISDIKTGREIHNGFM.-----V.GIDGKEFPLKKtK..K...RAD..HLDDNL..KIIR...ELKPRNEKSAIKGIKQISNYNAIMG.........GNY-..----------rlili......
E3IWI9_FRAIE/3211-3306                 ..................g-SNPAARTGQQVHKDFStILNGYGdVGYEGEFKLPS.G..L...RPDgaFTDPATgvRVPV...ELKPDTRSQIRRGLGELRVYEQEMGv.......pSGSG..QLWVYRVNP-q..........
H1Z991_MYROD/1194-1282                 ...................YTKSSLAFGREIHAGYKvAEHAPA.LGRFKEFTGIK.G..I...RPD..FVDFGT..KTIY...ELKPFNPRGIRSGTKQLNNYKSLFE.........QNYG..GTWKTVLDHY...........
F8KV49_PARAV/144-193                   ...................YTRSNLKHGQEMHRLYK.----LGvEGVKKEFRLPS.G..K...RID..ALDEPI.rKLIY...-------------------------.........----..----------ppk........
A0A037ZEC1_9RHOB/379-460               wqrygveqhkslggssncd-----------------.------.-VTERAIPTDS.S..S...RPD..CFRVPS..CTVV...EFKPNNDAEIRKGEGQLKRYKASLD.........SYYT..DLLQD-----llkp.......
F8KV51_PARAV/1-49                      .................mi-----------------.------.-----------.-..-...---..-----N..HIIY...ELKPFNPRSIKLGNKALEIYKQELQt......mpRFEG..IEWETILETY...........
Q5L196_GEOKA/2214-2301                 ...................YTKSNLKLGRQMHKSYK.ANKVLK.GVREKEFRLPS.G..K...RID..FIDFEK..KIIY...ELKPNNPRAIKKGLKQLKAYKKEVE.........KIYG..KGWRTVLEVY...........
A0A1H4D3T6_9BACT/31-108                ...................YTKSSLKLGQQMHKGYK.----VG.ADGIKEFRLPS.G..K...RID..FLDIKN..STIY...ELKPFNPRAMQQGQKQLNMYIRSY-.........----..----------rqchslkel..
G8M231_CLOCD/2887-2974                 ...................YTKSSLKMGQEMHKAYK.ADVVDN.ITKFKEFRLPS.G..K...RID..FIDFET..KTIY...ELKPYNPNGIKTGLKQLEVYLKEVE.........SIYG..GGWKTILDTY...........
H8KTP5_SOLCM/1076-1163                 ................gst---VANRLGQLMHKAYK.AADVLE.GVRIKEFRLPS.G..K...RID..FIDFEN..KIIY...ELKPNNPRAIKEGYKQLAMYLQEVE.........SIYG..KGFKTILDTY...........
A0A1F5QCW2_9BACT/2668-2754             ..................v-VKEALEYGKVQHSLFK.-ADEIG.PTFLKEFRFAN.G..L...RAD..AIDFKN..KVIY...ELKPENSRAIQQGYNQLRAYTEQAK.........NQFG..DTFKGVLETY...........
A0A1T5M3S2_9MICO/1994-2079             .................ge--NADAARGRATHLNYR.--DALG.GGYDYEVRLDS.G..R...RPD..AVNWAT..REVR...ELKSDAPSSMARGRRQLQGYVSELE.........SMTG..QPWTGHLDIY...........
A0A0G3A7N4_9DELT/1-48                  ..................m-----------------.------.-----------.-..-...---..--NAEK..QDVK...ELKPNNPRAIKRGEKQVETYRRELE.........EKRG..GQWTGQVETY...........
A0A1I5G881_9ACTN/2218-2303             .................ge--NADAARGRQTHLNYR.--SALG.AGYDFEVTLPS.G..L...RPD..AVDWKN..RVVR...ELKSDARSSQATGRRQLQKYVAELE.........DITG..QSWTGHLDTY...........
#=GC seq_cons                          .....................psshphGpphHpsY+.....hu.ssh.KEapLPS.G..+...RhD..hlDhps..+hIY...ELKPsNP+uI+pGhKQLphYhpElp.........phhG..ttWpshL-TY...........
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