GenomeNet

Database: Pfam
Entry: XK-related
LinkDB: XK-related
Original site: XK-related 
#=GF ID   XK-related
#=GF AC   PF09815.12
#=GF DE   XK-related protein
#=GF AU   KOGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   KOGs (KOG4790)
#=GF GA   24.80 24.80;
#=GF TC   24.80 25.10;
#=GF NC   24.50 24.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   8004674
#=GF RT   Isolation of the gene for McLeod syndrome that encodes a novel
#=GF RT   membrane transport protein. 
#=GF RA   Ho M, Chelly J, Carter N, Danek A, Crocker P, Monaco AP; 
#=GF RL   Cell. 1994;77:869-880.
#=GF RN   [2]
#=GF RM   7737196
#=GF RT   Purification and partial characterization of the erythrocyte Kx
#=GF RT   protein deficient in McLeod patients. 
#=GF RA   Khamlichi S, Bailly P, Blanchard D, Goossens D, Cartron JP,
#=GF RA   Bertrand O; 
#=GF RL   Eur J Biochem. 1995;228:931-934.
#=GF DR   INTERPRO; IPR018629;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Members of this family comprise various XK-related proteins,
#=GF CC   that are involved in sodium-dependent transport of neutral amino
#=GF CC   acids or oligopeptides. These proteins are responsible for the
#=GF CC   Kx blood group system - defects results in McLeod syndrome
#=GF CC   [MIM:314850], an X-linked multi-system disorder characterised by
#=GF CC   late onset abnormalities in the neuromuscular and hematopoietic
#=GF CC   systems [1][2].
#=GF SQ   3711
#=GS A0A3P9Q3T0_POERE/47-449     AC A0A3P9Q3T0.1
#=GS A0A4U5UMS1_COLLU/123-236    AC A0A4U5UMS1.1
#=GS A0A4U5UPD0_COLLU/1-221      AC A0A4U5UPD0.1
#=GS A0A2W1BY03_HELAM/33-374     AC A0A2W1BY03.1
#=GS A0A452SQU3_URSAM/35-407     AC A0A452SQU3.1
#=GS A0A6P6C1K0_PTEVA/8-333      AC A0A6P6C1K0.1
#=GS A0A6P4EAN8_DRORH/1-218      AC A0A6P4EAN8.1
#=GS A0A3Q0DBW1_MESAU/73-374     AC A0A3Q0DBW1.1
#=GS A0A2K5F3J0_AOTNA/9-345      AC A0A2K5F3J0.1
#=GS A0A6J1PVK0_9HYME/1-287      AC A0A6J1PVK0.1
#=GS A0A158QEA6_HYMDI/944-1413   AC A0A158QEA6.1
#=GS A0A6A5E1T0_PERFL/14-357     AC A0A6A5E1T0.1
#=GS A0A3Q2KP89_HORSE/126-486    AC A0A3Q2KP89.2
#=GS G3TXD5_LOXAF/58-440         AC G3TXD5.1
#=GS A0A667WLK6_9TELE/2-274      AC A0A667WLK6.1
#=GS A0A672MBA9_SINGR/178-393    AC A0A672MBA9.1
#=GS A0A1A6HCR4_NEOLE/1-74       AC A0A1A6HCR4.1
#=GS A0A671Z313_SPAAU/15-351     AC A0A671Z313.1
#=GS A0A672KF08_SINGR/1-306      AC A0A672KF08.1
#=GS A0A0P7Z9V1_SCLFO/15-343     AC A0A0P7Z9V1.1
#=GS A0A3Q2X7R9_HAPBU/9-340      AC A0A3Q2X7R9.1
#=GS A0A091J7C6_EGRGA/1-246      AC A0A091J7C6.1
#=GS A0A1V4JVA7_PATFA/2-304      AC A0A1V4JVA7.1
#=GS A0A3R7M4U2_PENVA/93-461     AC A0A3R7M4U2.1
#=GS A0A423TQ59_PENVA/212-348    AC A0A423TQ59.1
#=GS C3XXH6_BRAFL/12-271         AC C3XXH6.1
#=GS A0A672RAT4_SINGR/76-193     AC A0A672RAT4.1
#=GS A0A6J0VFV1_9SAUR/5-375      AC A0A6J0VFV1.1
#=GS A0A6P3I0T0_BISBI/1-213      AC A0A6P3I0T0.1
#=GS A0A669E418_ORENI/15-351     AC A0A669E418.1
#=GS W5LIZ1_ASTMX/106-458        AC W5LIZ1.1
#=GS A0A5E4PWC4_9NEOP/33-195     AC A0A5E4PWC4.1
#=GS A0A4U5UMF5_COLLU/123-236    AC A0A4U5UMF5.1
#=GS A0A6I8TF49_AEDAE/452-604    AC A0A6I8TF49.1
#=GS A0A2T7NRM3_POMCA/12-150     AC A0A2T7NRM3.1
#=GS A0A3Q0EAL2_CARSF/79-269     AC A0A3Q0EAL2.1
#=GS A0A553QII3_9TELE/91-466     AC A0A553QII3.1
#=GS A0A3Q2CH48_CYPVA/40-409     AC A0A3Q2CH48.1
#=GS A0A6P6HTD2_PUMCO/9-345      AC A0A6P6HTD2.1
#=GS A0A3Q3L9Y6_9TELE/2-308      AC A0A3Q3L9Y6.1
#=GS A0A672TAT8_SINGR/8-316      AC A0A672TAT8.1
#=GS A0A0L7K326_9NEOP/35-88      AC A0A0L7K326.1
#=GS A0A6I9Q311_9TELE/15-178     AC A0A6I9Q311.1
#=GS A0A6I9Q575_9TELE/15-172     AC A0A6I9Q575.1
#=GS A0A226PJ73_COLVI/5-125      AC A0A226PJ73.1
#=GS A0A4W6EDW7_LATCA/63-259     AC A0A4W6EDW7.1
#=GS A0A151J804_9HYME/366-529    AC A0A151J804.1
#=GS A0A2K5KUX6_CERAT/14-343     AC A0A2K5KUX6.1
#=GS A0A3Q2WB18_HAPBU/41-157     AC A0A3Q2WB18.1
#=GS A0A556TSS9_BAGYA/85-436     AC A0A556TSS9.1
#=GS A0A2K6MRY8_RHIBE/5-279      AC A0A2K6MRY8.1
#=GS A0A6F9B5D3_9TELE/97-466     AC A0A6F9B5D3.1
#=GS A0A443RE69_9ACAR/101-341    AC A0A443RE69.1
#=GS A0A6P3GLA5_BISBI/6-234      AC A0A6P3GLA5.1
#=GS A0A0R3UMU6_9CEST/111-237    AC A0A0R3UMU6.1
#=GS A0A2I4BEF6_9TELE/82-436     AC A0A2I4BEF6.1
#=GS I3N3P8_ICTTR/5-375          AC I3N3P8.1
#=GS M3ZPX0_XIPMA/85-435         AC M3ZPX0.1
#=GS I3NGP1_ICTTR/115-514        AC I3NGP1.2
#=GS K7F6W6_PELSI/1-222          AC K7F6W6.1
#=GS A0A643BZU8_BALPH/1-203      AC A0A643BZU8.1
#=GS A0A2Y9FTX0_PHYMC/9-345      AC A0A2Y9FTX0.1
#=GS A0A6J2UN89_CHACN/44-416     AC A0A6J2UN89.1
#=GS A0A6A5ERS9_PERFL/12-347     AC A0A6A5ERS9.1
#=GS A0A6P7L4A4_BETSP/82-478     AC A0A6P7L4A4.1
#=GS G3QR93_GORGO/1-366          AC G3QR93.1
#=GS E4XXD9_OIKDI/15-337         AC E4XXD9.1
#=GS A0A6P4IBH9_DROKI/285-436    AC A0A6P4IBH9.1
#=GS A0A671PRR3_9TELE/1-304      AC A0A671PRR3.1
#=GS A0A669B5N3_ORENI/82-398     AC A0A669B5N3.1
#=GS A0A6G1P8B5_9TELE/313-424    AC A0A6G1P8B5.1
#=GS A0A7N8WHJ4_9TELE/292-358    AC A0A7N8WHJ4.1
#=GS A0A232FDP8_9HYME/45-187     AC A0A232FDP8.1
#=GS A0A2J7QVM6_9NEOP/13-354     AC A0A2J7QVM6.1
#=GS A0A668SVA1_OREAU/44-183     AC A0A668SVA1.1
#=GS A0A6F9BVV4_9TELE/53-347     AC A0A6F9BVV4.1
#=GS A0A2F0BA76_ESCRO/35-200     AC A0A2F0BA76.1
#=GS A0A1D5QM29_MACMU/35-402     AC A0A1D5QM29.1
#=GS A0A6Q8PFG6_HUMAN/14-188     AC A0A6Q8PFG6.1
#=GS B7PU68_IXOSC/146-248        AC B7PU68.1
#=GS A0A2K5TWG1_MACFA/48-420     AC A0A2K5TWG1.2
#=GS XKR5_PANTR/4-320            AC Q49LS3.1
#=GS H2TIE7_TAKRU/82-477         AC H2TIE7.2
#=GS S7N4V9_MYOBR/40-260         AC S7N4V9.1
#=GS A0A670KBI5_PODMU/5-88       AC A0A670KBI5.1
#=GS A0A670XWK8_PSETE/121-524    AC A0A670XWK8.1
#=GS A0A3P9D6E2_9CICH/5-375      AC A0A3P9D6E2.1
#=GS A0A0L7QV89_9HYME/80-393     AC A0A0L7QV89.1
#=GS A0A3P9A0M0_ESOLU/79-475     AC A0A3P9A0M0.1
#=GS A0A7M7LU53_NASVI/33-397     AC A0A7M7LU53.1
#=GS A0A673M6T6_9TELE/1-348      AC A0A673M6T6.1
#=GS A0A2U9BKZ2_SCOMX/1112-1436  AC A0A2U9BKZ2.1
#=GS E9GXU8_DAPPU/42-328         AC E9GXU8.1
#=GS A0A6P7IVV4_9TELE/47-453     AC A0A6P7IVV4.1
#=GS I3K824_ORENI/16-373         AC I3K824.1
#=GS A0A2K5HVB5_COLAP/11-381     AC A0A2K5HVB5.1
#=GS A0A2G9QGI0_LITCT/181-382    AC A0A2G9QGI0.1
#=GS A0A6P6M9B0_CARAU/44-424     AC A0A6P6M9B0.1
#=GS A0A5N5JEU1_PANHP/1-75       AC A0A5N5JEU1.1
#=GS A0A0N4V3I7_ENTVE/56-395     AC A0A0N4V3I7.1
#=GS A0A672YPP9_9TELE/1-249      AC A0A672YPP9.1
#=GS A0A0P7U636_SCLFO/47-371     AC A0A0P7U636.1
#=GS A0A673VG28_SURSU/5-375      AC A0A673VG28.1
#=GS A0A2G9QGI0_LITCT/85-194     AC A0A2G9QGI0.1
#=GS XKR7_PANTR/58-441           AC Q49LS1.1
#=GS A0A673G7U2_9TELE/1-304      AC A0A673G7U2.1
#=GS A0A6P8Q4M2_GEOSA/88-489     AC A0A6P8Q4M2.1
#=GS A0A5N5TMY3_9CRUS/675-913    AC A0A5N5TMY3.1
#=GS A0A6P6J687_CARAU/110-485    AC A0A6P6J687.1
#=GS A0A061ADU5_ONCMY/90-198     AC A0A061ADU5.1
#=GS F7CWH2_MONDO/111-483        AC F7CWH2.2
#=GS A0A2K5R323_CEBIM/35-407     AC A0A2K5R323.1
#=GS A0A2K5Y8B5_MANLE/19-421     AC A0A2K5Y8B5.1
#=GS A0A0D9S817_CHLSB/14-343     AC A0A0D9S817.1
#=GS A0A6J3BVF1_VICPA/1-241      AC A0A6J3BVF1.1
#=GS F6ZP62_HORSE/58-441         AC F6ZP62.2
#=GS A0A3Q4MTP7_NEOBR/16-141     AC A0A3Q4MTP7.1
#=GS A0A3Q1HTC2_ANATE/292-358    AC A0A3Q1HTC2.1
#=GS A0A6P9B0R4_PANGU/95-457     AC A0A6P9B0R4.1
#=GS A0A1V4KGI6_PATFA/10-205     AC A0A1V4KGI6.1
#=GS A0A6F9B1M5_9TELE/98-295     AC A0A6F9B1M5.1
#=GS A0A672MGF5_SINGR/42-159     AC A0A672MGF5.1
#=GS A0A6P6N083_CARAU/81-196     AC A0A6P6N083.1
#=GS A0A096NUZ3_PAPAN/58-441     AC A0A096NUZ3.1
#=GS A0A3Q2VMX1_HAPBU/88-442     AC A0A3Q2VMX1.1
#=GS A0A3P9P552_POERE/40-407     AC A0A3P9P552.1
#=GS V8P578_OPHHA/456-785        AC V8P578.1
#=GS A0A674D1Z6_SALTR/39-408     AC A0A674D1Z6.1
#=GS A0A093HZK4_STRCA/1-294      AC A0A093HZK4.1
#=GS A0A0L7KX11_9NEOP/33-234     AC A0A0L7KX11.1
#=GS A0A091XJ59_OPIHO/1-247      AC A0A091XJ59.1
#=GS A0A5N4B2H2_PHOPY/1-234      AC A0A5N4B2H2.1
#=GS A0A3B1JPC6_ASTMX/49-425     AC A0A3B1JPC6.1
#=GS A0A672NAA5_SINGR/44-415     AC A0A672NAA5.1
#=GS A0A4W5PXD8_9TELE/40-409     AC A0A4W5PXD8.1
#=GS E2BJP2_HARSA/374-532        AC E2BJP2.1
#=GS A0A3N0Y0L8_ANAGA/1-303      AC A0A3N0Y0L8.1
#=GS A0A3P9CGZ7_9CICH/83-433     AC A0A3P9CGZ7.1
#=GS A0A674E3U3_SALTR/27-344     AC A0A674E3U3.1
#=GS X6M906_RETFI/22-138         AC X6M906.1
#=GS A0A6J2V900_CHACN/81-436     AC A0A6J2V900.1
#=GS A0A673I0S8_9TELE/15-354     AC A0A673I0S8.1
#=GS A0A2U9C9J4_SCOMX/5-375      AC A0A2U9C9J4.1
#=GS A0A091EAV7_CORBR/1-247      AC A0A091EAV7.1
#=GS V4CF30_LOTGI/12-345         AC V4CF30.1
#=GS A0A669BX17_ORENI/16-351     AC A0A669BX17.1
#=GS T1IQT0_STRMM/46-382         AC T1IQT0.1
#=GS A0A668UGY8_OREAU/82-297     AC A0A668UGY8.1
#=GS A0A3P8UIG3_CYNSE/38-355     AC A0A3P8UIG3.1
#=GS A0A3Q2X7W6_HAPBU/16-365     AC A0A3Q2X7W6.1
#=GS A0A671Z351_SPAAU/21-353     AC A0A671Z351.1
#=GS A0A482VLX3_9CUCU/11-323     AC A0A482VLX3.1
#=GS A0A672KYC8_SINGR/15-350     AC A0A672KYC8.1
#=GS A0A5A9NLH0_9TELE/157-317    AC A0A5A9NLH0.1
#=GS A0A212C2K2_CEREH/180-244    AC A0A212C2K2.1
#=GS A0A668U1E4_OREAU/16-330     AC A0A668U1E4.1
#=GS A0A6P5ACR5_BRABE/45-370     AC A0A6P5ACR5.1
#=GS A0A1Y3ASS4_EURMA/1-250      AC A0A1Y3ASS4.1
#=GS A0A0N4UC25_DRAME/27-417     AC A0A0N4UC25.1
#=GS A0A3B3HS27_ORYLA/6-247      AC A0A3B3HS27.1
#=GS A0A6P6NUG2_CARAU/17-361     AC A0A6P6NUG2.1
#=GS A0A553MUN4_9TELE/42-179     AC A0A553MUN4.1
#=GS A0A0L0CEA5_LUCCU/30-222     AC A0A0L0CEA5.1
#=GS A0A671W1Q0_SPAAU/43-412     AC A0A671W1Q0.1
#=GS A0A093GX40_DRYPU/1-246      AC A0A093GX40.1
#=GS A0A672VAL1_STRHB/21-390     AC A0A672VAL1.1
#=GS I3K208_ORENI/88-442         AC I3K208.2
#=GS A0A663MQY2_ATHCN/4-251      AC A0A663MQY2.1
#=GS G1SR92_RABIT/5-375          AC G1SR92.1
#=GS A0A674JBH6_TERCA/112-515    AC A0A674JBH6.1
#=GS H0V750_CAVPO/1-241          AC H0V750.2
#=GS A0A4X2JQX3_VOMUR/5-374      AC A0A4X2JQX3.1
#=GS A0A6I9M9Y6_PERMB/5-317      AC A0A6I9M9Y6.1
#=GS A0A452FSD5_CAPHI/141-418    AC A0A452FSD5.1
#=GS A0A2U9CVC2_SCOMX/81-463     AC A0A2U9CVC2.1
#=GS A0A096M5B2_POEFO/2-264      AC A0A096M5B2.1
#=GS A0A3Q4B7Y7_MOLML/1-252      AC A0A3Q4B7Y7.1
#=GS A0A673U337_SURSU/35-407     AC A0A673U337.1
#=GS A0A4W4HIX1_ELEEL/4-291      AC A0A4W4HIX1.1
#=GS A0A2Y9GXH4_NEOSC/118-520    AC A0A2Y9GXH4.1
#=GS A0A444UZ01_ACIRT/35-135     AC A0A444UZ01.1
#=GS A0A3Q3AKI1_KRYMA/89-440     AC A0A3Q3AKI1.1
#=GS A0A3R7Q4C0_PENVA/689-1105   AC A0A3R7Q4C0.1
#=GS H0X6X5_OTOGA/59-442         AC H0X6X5.1
#=GS A0A2K6AGV1_MANLE/6-367      AC A0A2K6AGV1.1
#=GS A0A3L8RYD0_CHLGU/16-344     AC A0A3L8RYD0.1
#=GS A0A5N5KSP7_PANHP/9-338      AC A0A5N5KSP7.1
#=GS A0A484CJA2_PERFV/15-351     AC A0A484CJA2.1
#=GS A0A368HAT0_ANCCA/46-402     AC A0A368HAT0.1
#=GS A0A1U7QV24_MESAU/126-496    AC A0A1U7QV24.1
#=GS C3XXH8_BRAFL/14-338         AC C3XXH8.1
#=GS A0A151WJE3_9HYME/42-404     AC A0A151WJE3.1
#=GS A0A2K6KQ89_RHIBE/5-375      AC A0A2K6KQ89.1
#=GS A0A1Q9DWL0_SYMMI/1-204      AC A0A1Q9DWL0.1
#=GS G3R1T2_GORGO/20-309         AC G3R1T2.2
#=GS A0A2K5PAT4_CEBIM/5-375      AC A0A2K5PAT4.1
#=GS A0A6P6PK09_CARAU/1-197      AC A0A6P6PK09.1
#=GS A0A091F622_CORBR/10-346     AC A0A091F622.1
#=GS A0A6P6N6Q9_CARAU/40-411     AC A0A6P6N6Q9.1
#=GS A0A2B4SA35_STYPI/261-600    AC A0A2B4SA35.1
#=GS A0A6A4X0G8_AMPAM/1-168      AC A0A6A4X0G8.1
#=GS A0A1A6GIP9_NEOLE/1-136      AC A0A1A6GIP9.1
#=GS Q49M60_CHICK/15-342         AC Q49M60.1
#=GS A0A484D4A0_PERFV/44-425     AC A0A484D4A0.1
#=GS A0A0P7U2A3_SCLFO/1-245      AC A0A0P7U2A3.1
#=GS W5JDY2_ANODA/28-228         AC W5JDY2.1
#=GS A0A6J2WFM6_CHACN/15-351     AC A0A6J2WFM6.1
#=GS A0A162PEX5_9CRUS/12-342     AC A0A162PEX5.1
#=GS H3CJ44_TETNG/15-348         AC H3CJ44.1
#=GS XK_RAT/5-374                AC Q5GH61.1
#=GS A0A401SKZ1_CHIPU/80-203     AC A0A401SKZ1.1
#=GS A0A286Y5Y0_CAVPO/5-375      AC A0A286Y5Y0.1
#=GS A0A6I9L4H0_PERMB/5-375      AC A0A6I9L4H0.1
#=GS A0A4W6E0N7_LATCA/85-459     AC A0A4W6E0N7.1
#=GS A0A194PMH6_PAPXU/33-232     AC A0A194PMH6.1
#=GS A0A4W6EKP1_LATCA/87-283     AC A0A4W6EKP1.1
#=GS A0A3P8V120_CYNSE/5-375      AC A0A3P8V120.1
#=GS A0A484BC21_DRONA/32-227     AC A0A484BC21.1
#=GS A0A3Q7U854_VULVU/92-363     AC A0A3Q7U854.1
#=GS A0A3P8U038_AMPPE/14-357     AC A0A3P8U038.1
#=GS A0A3Q3GRN8_9LABR/88-442     AC A0A3Q3GRN8.1
#=GS A0A6J1UPX2_9SAUR/49-418     AC A0A6J1UPX2.1
#=GS F1PKR1_CANLF/59-442         AC F1PKR1.2
#=GS C3YB08_BRAFL/38-274         AC C3YB08.1
#=GS A0A673Y5X9_SALTR/15-350     AC A0A673Y5X9.1
#=GS A0A6A4JU62_APOLU/30-219     AC A0A6A4JU62.1
#=GS A0A4W6ECP4_LATCA/38-397     AC A0A4W6ECP4.1
#=GS A0A4W4FW79_ELEEL/45-178     AC A0A4W4FW79.1
#=GS A0A6I9YU45_9SAUR/119-486    AC A0A6I9YU45.1
#=GS A0A2Y9IVB4_ENHLU/14-343     AC A0A2Y9IVB4.1
#=GS A0A016TM52_9BILA/58-409     AC A0A016TM52.1
#=GS A0A7E4S710_CIMLE/47-363     AC A0A7E4S710.1
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