GenomeNet

Database: Pfam
Entry: ANAPC9
LinkDB: ANAPC9
Original site: ANAPC9 
#=GF ID   ANAPC9
#=GF AC   PF12856.8
#=GF DE   Anaphase-promoting complex subunit 9
#=GF PI   Apc9;
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   manual
#=GF GA   25.00 25.00;
#=GF TC   25.00 25.80;
#=GF NC   24.90 24.70;
#=GF BM   hmmbuild --amino HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9469814
#=GF RT   Mass spectrometric analysis of the anaphase-promoting complex
#=GF RT   from yeast: identification of a subunit related to cullins.
#=GF RA   Zachariae W, Shevchenko A, Andrews PD, Ciosk R, Galova M, Stark
#=GF RA   MJ, Mann M, Nasmyth K;
#=GF RL   Science. 1998;279:1216-1219.
#=GF RN   [2]
#=GF RM   16896351
#=GF RT   The anaphase promoting complex/cyclosome: a machine designed to
#=GF RT   destroy.
#=GF RA   Peters JM;
#=GF RL   Nat Rev Mol Cell Biol. 2006;7:644-656.
#=GF RN   [3]
#=GF RM   20037474
#=GF RT   APC-targeted RAA1 degradation mediates the cell cycle and root
#=GF RT   development in plants.
#=GF RA   Xu Y, Cao H, Chong K;
#=GF RL   Plant Signal Behav. 2010; [Epub ahead of print]
#=GF DR   INTERPRO; IPR024274;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Apc9 is one of the subunits of the anaphase-promoting complex,
#=GF CC   or cyclosome [1], which is essential for regulating entry into
#=GF CC   anaphase and exit from mitosis. The APC is a ubiquitin-protein
#=GF CC   ligase complex. All APC subunits are members of the cullin
#=GF CC   family proteins, which bind to a ring-finger subunit via a
#=GF CC   conserved cullin domain [2]. The APC is made up of four parts,
#=GF CC   the third of which is a tetratricopeptide repeat arm (TPR) that
#=GF CC   contains Apc9 [3].
#=GF SQ   46
#=GS A0A1X7R854_9SACH/53-189   AC A0A1X7R854.1
#=GS C5DVG2_ZYGRC/91-200       AC C5DVG2.1
#=GS A0A1E4T7B8_9ASCO/95-224   AC A0A1E4T7B8.1
#=GS A0A1G4KIS3_9SACH/45-145   AC A0A1G4KIS3.1
#=GS A0A2P7YYC0_9ASCO/81-223   AC A0A2P7YYC0.1
#=GS Q74ZY8_ASHGO/22-143       AC Q74ZY8.1
#=GS G3B997_CANTC/94-237       AC G3B997.1
#=GS A0A2V1ARR8_9ASCO/83-142   AC A0A2V1ARR8.1
#=GS M3J7B7_CANMX/91-216       AC M3J7B7.1
#=GS A0A0C7MZK5_9SACH/40-156   AC A0A0C7MZK5.1
#=GS G8BR83_TETPH/66-195       AC G8BR83.1
#=GS A0A1E3PC06_WICAA/23-134   AC A0A1E3PC06.1
#=GS A0A2V1ARR8_9ASCO/143-226  AC A0A2V1ARR8.1
#=GS I2H3E5_TETBL/2-83         AC I2H3E5.1
#=GS A0A421J6S9_9ASCO/80-184   AC A0A421J6S9.1
#=GS G8JTI8_ERECY/24-152       AC G8JTI8.1
#=GS A7TJ18_VANPO/71-180       AC A7TJ18.1
#=GS A5DJ78_PICGU/105-206      AC A5DJ78.2
#=GS Q6FIV2_CANGA/50-170       AC Q6FIV2.1
#=GS G3AP46_SPAPN/120-237      AC G3AP46.1
#=GS G0W681_NAUDC/89-201       AC G0W681.1
#=GS A0A1A0HG16_9ASCO/87-218   AC A0A1A0HG16.1
#=GS A0A1E4S0K6_CYBJN/7-130    AC A0A1E4S0K6.1
#=GS C5M8F9_CANTT/116-242      AC C5M8F9.1
#=GS G8XZE5_PICSO/97-208       AC G8XZE5.1
#=GS A3LR49_PICST/104-232      AC A3LR49.2
#=GS A0A1L0BNV3_9ASCO/80-216   AC A0A1L0BNV3.1
#=GS APC9_YEAST/56-170         AC Q12107.1
#=GS G8ZX85_TORDC/56-172       AC G8ZX85.1
#=GS A0A2U9QY13_PICKU/134-267  AC A0A2U9QY13.1
#=GS A0A421JTJ3_9ASCO/110-217  AC A0A421JTJ3.1
#=GS A0A1E4RP93_9ASCO/85-272   AC A0A1E4RP93.1
#=GS A0A1E4SHA5_9ASCO/49-185   AC A0A1E4SHA5.1
#=GS C4R1A1_KOMPG/18-155       AC C4R1A1.1
#=GS G0V9I8_NAUCC/56-173       AC G0V9I8.1
#=GS A0A367XWM2_9ASCO/115-236  AC A0A367XWM2.1
#=GS S6F6E3_ZYGB2/66-177       AC S6F6E3.1
#=GS C4XZ90_CLAL4/76-213       AC C4XZ90.1
#=GS Q6BPI0_DEBHA/91-215       AC Q6BPI0.2
#=GS G8Y2D8_PICSO/97-208       AC G8Y2D8.1
#=GS A0A367YIR5_9ASCO/118-239  AC A0A367YIR5.1
#=GS A0A1G4MK66_LACFM/40-137   AC A0A1G4MK66.1
#=GS A0A2H0ZL46_CANAR/85-228   AC A0A2H0ZL46.1
#=GS G8BHL7_CANPC/199-266      AC G8BHL7.1
#=GS A0A1D8PN73_CANAL/122-251  AC A0A1D8PN73.1
#=GS J5RT37_SACK1/57-168       AC J5RT37.1
A0A1X7R854_9SACH/53-189              .................lrrktkrslkvsidndslrtcptnvvseed----------------------.--------.......................................--VQN..E.LTNVEYDFHPFTTKRS-....................--------ISETKRKNWLSAETAEHCLIFHKEghlqgtvnyrpdimidcepkstsgsdiliD-----..--.-----..................---------------------ypenikdsysnirndknkvrkskdtgnngqire
C5DVG2_ZYGRC/91-200                  ...........................vssgkeeleidtvldenels----------------------.--------.......................................KEPSL..P.AEEAEYDYKPFSEKPL-....................--------LRESKIESYLQAERAAHCLIFHTSghipga.................ddkyrpDAELEC..GE.DEWEG..................--QELNHDEGPLLLSVPGC--sk...............................
A0A1E4T7B8_9ASCO/95-224              ...............................asksqtinftpnsays-----------SSSSTSNSTDI.NTAKSTDK.......................................LIIRK..DeSDLNEYDYKTFSTSHP-....................--------LRVSKVKAFEQSEM-TTRLYFSKDdd........................fneDDDVTI..KS.----Katsksnn....hyfkksrPSSTDNKERDDIVIQVPG---msr..............................
A0A1G4KIS3_9SACH/45-145              .............................snifetpqpvptprvpgk----------------------.--------.......................................-----..-.-DAESYDYSPFCDKKL-....................--------LRESKQLQLQQSEIATHCLVFHNArqgdp...................illrpDMNLWC..CD.SSDDE..................--HEG----------------lrnddsavpavfdnagya...............
A0A2P7YYC0_9ASCO/81-223              .............................................ak--ASKKLLNFQQLKKS------.--YAPTQP.......................................FVLHK..P.ADMSHYDYLVFTKQHNTsrrspviapqslllptspaePVKPSLPPVRLTQIKAWESAETITSNRVFDYA.............................KQDDEAwlDD.DTYEFgadeev......sidrgnD--------------------ewtepnvsntiialipel...............
Q74ZY8_ASHGO/22-143                  ..........kspqmkqhtqqgqqtplrrprcilgapyepsrasstg----------------------.--------.......................................-----..A.GQKRDYDYSVFNESRL-....................--------LTESKIDQYLKSEAATHKRVFHRDrphd....................dsyrpDLQPLC..CD.SSDEEg...............epRRAQSARGDRPLVLSIPG---i................................
G3B997_CANTC/94-237                  ..............................................d-LVKNKLLNLHKSSRIYTKSKS.ISEEDAMRshpn..............................fttksFILRK..P.LHMNLYDYSVFRSYPDAs..................aGDDKLPPAVKESQIKAWESAEKITNNLIFDNDs..........................dlS---DD..EDiNEGEThhdiag.....dmvrpldSSSVPAGGDDTIIKSIPGFC-k................................
A0A2V1ARR8_9ASCO/83-142              .............................................ak--ASKKLLNLQQSRKSY-----.---APPQP.......................................FVLHK..P.ADMSHFDYSVFTKKQKSl..................kEKNAMAP-------------------------.............................------..--.-----..................---------------------qssssp...........................
M3J7B7_CANMX/91-216                  ...............................................RLVKTKLLNLQQSSRQQLMNRI.KDDHNSKTvdeilvpk.......................hnsfpphlLGNTK..P.PSPNTFDCSVFTNVDVN...................rQSHSLFTPIKESKVKAWESAEKVAQSIIFDND.............................DSDSDA..FS.DDDKE..................----------NCVVSIPGYTK.................................
A0A0C7MZK5_9SACH/40-156              ............................llddrdifesprnaiedaa----------------------.------AS.......................................SHQRR..A.KDPEVYDFTPFCDKKL-....................--------LAASKLDNMLSSESATHCLVFHKDkhraletagkk.......kfrpdldlwccDSSEDE..QE.EEKEE..................--EEEEG--------------essslvdnsc.......................
G8BR83_TETPH/66-195                  ........................................mnnelgi--------EIDGSNQEHQSQKN.RRYINSSG.......................................FGISNnsE.ANSTEYDFQTFSLKFQ-....................--------LQETKKNNILRSERAAHCLVFHKSahnyn..................kneyrpDLYFDC..GE.----Nldkssn......llhmksSQETYDESNALLLESLPGYTN.................................
A0A1E3PC06_WICAA/23-134              .................................nldsatsnllsrtl---------------RKNSDKY.LNKSNNEPge...................................reFVIHK..S.TKPE--DYEIFSTSHP-....................--------IRESKLQALEQSEQAFNE-VFHAGf...........................dDSGSED..EEpDVSAI..................-ASPSVMNEDDILISVPGYSK.................................
A0A2V1ARR8_9ASCO/143-226             ......................................sspaeplkp----------------------.--------.......................................-----..-.-----------------....................----ALPPVRSSQIKAWESAESVSCNRVFEYS.............................KQDDEL..WF.DDDSYdfgaeee....vsidrgtDEWNEPSSSNEAIASIP----els..............................
I2H3E5_TETBL/2-83                    ............................................sla----------------------.--------.......................................-----..-.-NTDDYDCTPLCDKIT-....................--------IRESKKESWLKSEQASHCLIFHKNghsrdd.................ianyrpD-----..--.-----..................---------------------lqiscgeksffnnkepqcrpnirkteg......
A0A421J6S9_9ASCO/80-184              .............................................ap--LKSKLLDLQQSQKYAKPTRI.TDFSGPGG.......................................-----..-.GFATGYDYSVFVDATSG....................--ELGPRAVKESQIKAWESAERIAANVIFDS-.............................DSDDEV..ET.-----..................ATPTRSPEHTSVLEAVPGYTK.................................
G8JTI8_ERECY/24-152                  ........rhikqsnqqtplrrprcilgapyetgssfqplssaaida----------------------.--------.......................................-ASTK..Q.L-QKEYDYSVFNKSRL-....................--------LTESKIDQYLKSEIATHKRVFHRDkvhd....................dsyrpDLQPLC..CD.SSDEEsd.............lisKRLHNQRVERPLVVSMPG---l................................
A7TJ18_VANPO/71-180                  ........................qfeisnvlmargqskdkleelhk----------------------.--------.......................................--FGL..S.EEYDEYDCYSLTNKTL-....................--------VRESKIQNFLQSERAVHCLVFHKDahinq..................mdsyrpDINYNC..GDgDELDS..................---KEVREDSSLLINVPGYTN.................................
A5DJ78_PICGU/105-206                 .............................................ap--LKSKLLDLQSSRKYAKPTKQ.TSFSTSFG.......................................-----..-.---PGYDYSVFVDATTG....................--ELGPRAVKESQVKAWESAERIAANVIFDS-.............................DSEDEV..ES.-----..................ATPTRNPEPTTVLEAIPGYTK.................................
Q6FIV2_CANGA/50-170                  .............................irishgntihvpkrnigr----------------------.--------.......................................-VSKK..PsINIQEYDYSPFFNRKA-....................--------IRESQIKSLLECERAAHCLVFHKDchini...................defrpDVDIYC..GEfDDYSIenldpp......hqestiDSALNERQRGVLQHTLPNYT-g................................
G3AP46_SPAPN/120-237                 ...............................................RLVKSKLLNLHQSSKLVFDDKS.LPKISHKS.......................................KTIGS..K.QEPGPYDYSIFTHYRNG....................-NGDVAPATRESQIRAWESSERIAQSVIFPSS.............................DSEVDD..LE.EEEEE..................EENQEEGVVECPIVSIPGYT-v................................
G0W681_NAUDC/89-201                  ...................................trnddidyvmdd----------------------.---KDHLN.......................................SSHRE..E.EEGYKYDYRPFIDKDL-....................--------VQEHKINNLLRSEKAIHCLIFHKNghsnests............ffmedsykpDLQLHC..GD.EDGDE..................IHDQAQYPAGSLITRIPN---cn...............................
A0A1A0HG16_9ASCO/87-218              .............................................at--ASKKLLNLQQLRRAQTN---.-----PRP.......................................FVLRK..P.ATMAKYDYSAFVDCHTNs.................etGDVNIPPLVKDSQVRAWKSAEKISAEIIFENGsssss...................pndttD-----..--.-VLDEgdgnslne..darasvegCDTDEAPSASVLLESIPQYTK.................................
A0A1E4S0K6_CYBJN/7-130               ...............qdvkrqlfkgvssrkpasfesaasnllsrtlr----------------KQSDKY.KRPMDDTR.......................................FVIHK..S.TSPE--DYLLF-NSQH-....................-------PMRESRLQAFSQAEQTFEEIFDGYD.............................DSGSED..DE.PDLSN..................VARSSELIKDDILISVPGYS-r................................
C5M8F9_CANTT/116-242                 ...............................................RLVKSKLLNLQQSSKQQLINKI.SEESPRSGikhyhgd........................nrmkfpphFALGK..P.EK-SSFDCKIYSKSVVP....................HKNKLFTPIRESQLNAWESAESVTRNLVFNND.............................SSDDES..DD.DCDET..................------KNNDNAIVSIPGYTQ.................................
G8XZE5_PICSO/97-208                  ..............................................n-MLKNKLLNLQSSKKYSKKDFD.LAGSGAG-.......................................FLSAN..S.LVSGGYDYGVFVSANGGas................gpEDKSMPPLVKQSQIKAWESAEKVSQKLIFDDS.............................DTEEGA..KD.DSGSD..................----------EIITSIPGYTK.................................
A3LR49_PICST/104-232                 ...............................................RLIKSKLLNLHQSSKQKTTWKY.HPNKSVPS.......................................FIIRK..P.INMNGYDYSVFTNYPTEid................lqHGEHLPPAIKESQIKSWESAERISTNVIFGNS............................sESEDDI..DElDEDEHte..............asRSSKVNSRKNNVIQAIPGYT-r................................
A0A1L0BNV3_9ASCO/80-216              ............................................nat----RKILNLQQLRKTYLN---.-----PKP.......................................FVLRK..P.INMTKYDYSVFSEHPMGl.................slEEDELPPPIKESQIRAWESAEKISANIIFENTqssssg.................tfgifeDVNKEM..DT.SLDEElhaeae......tsinrgNSSPSSRAREETLQSVPGYTK.................................
APC9_YEAST/56-170                    ....................evleertaddlyginmdvdevdylntl----------------------.--------.......................................---SH..I.EEEKQYDYSPFCERNT-....................--------LRESRIDSFLKAERAAHCLVFHKVghldg..................idsyrpDIDIMC..GE.EANKY..................DSANPEGNGSMLLESVPG---cnk..............................
G8ZX85_TORDC/56-172                  .............sasllvyhshegnesqedvgdsgltdgilnikgl----------------------.--------.......................................----K..D.HNDLDYDYKPLLRKHL-....................--------IAESKLRDLLQSERAAHCLIFHKKghagd..................mttyrpDLEWEC..SD.YEDEP..................----DIDDNGSVLQGIPG---csk..............................
A0A2U9QY13_PICKU/134-267             tptlnlklknskirnilcnssatnerggkfldieacspasanseasf----------------------.--LSKTESl.....................................iINNES..K.NDMDEYDYKTFSTNHP-....................--------LRLSKVKAFEQGEM-TTKMFFSKF.............................NSNCIK..NK.DCNKR..................NTYTRHSTDERLILQVPGI--sk...............................
A0A421JTJ3_9ASCO/110-217             ...............................................RLVKSKLLNLQQSSKIMFDDNKcLGKISQDQkatss.............................tiggaGGVSD..K.TRAEVYDYSIFTEHVPG....................--------TRESQIKAWESGERITHNVIFPCS.............................DDEEED..--.-----..................-------GNERPIISIPGYT-i................................
A0A1E4RP93_9ASCO/85-272              .............................................ln--VKKKLLNLQQSLKRKYPLS-.SPTSENTTrlqpaagpttnkspkynskendsgnhyiknlspmksnknFILRK..P.MNMNRYDYSIFINNDYNnyyfds.......sndvnlsHEVHIPPIIKESQIKAWESAEKITNNLIFDSS.............................SDDDDD..ND.DDNEEidnidfdtsmeeikqtvhDDLNLNSNNTLCIQSIPGLTK.................................
A0A1E4SHA5_9ASCO/49-185              ...............................................RLIKTKLLNLHQSQKRSIDKAY.GDSGDGEGdngiydvevd...................pshpnqsvpsFILHK..P.INMNSYDYSVFTNYPDGtd................lqHGEHLPPAVKESQIKAWESAEKISRNVIFGD-.............................ASDSDD..GE.SDVDH..................-----NPESAPYVTYLPGYS-r................................
C4R1A1_KOMPG/18-155                  ............nrisdteepanktptnhrilssfaykskttpetas----------------------.------EGnttd...............................rvllNQSAN..E.LDYIDYDYRIFNTKH--....................-------PLRWSKIKALEQSET-TTNYFFDTEsestdri..............htlnyglhSSATN-..DD.DDNDD..................DNDDSDSESNRVLEIIPGLTK.................................
G0V9I8_NAUCC/56-173                  ...................................rrpkrpllqqlv----------QQEQEQSEVN-I.DDIIEDMVg.....................................vKAKKT..R.YDNIPYNYHPFIDKAM-....................--------IRQNKMNNFLQSERAVHCLIFHKEghssdn.................fdeyrpDIDWNC..GD.DRDTA..................------LDKRSLITSLPN---cn...............................
A0A367XWM2_9ASCO/115-236             ...............................................RLVKTKLLNLQQSLKQQLINRI.SEEQPRQGqqhyssd........................sriqfpphFALGK..P.EE-KSFDCGIYTRAVER....................NRNELFPAVRESQIKAWESAERATRNLVFGND.............................SSEDES..DD.DEHDN..................-----------AIVSIPGYTQ.................................
S6F6E3_ZYGB2/66-177                  .............................pafssagaavdqteqqet----------------------.--------.......................................VGQLS..L.KDDAEYDFSPFSEKSL-....................--------LRESKIEAFLQAERAAHCLIFHKGghcnsd.................adkyrpDFDCDC..EDtDGEET.................kIHEYRYKDNGPLLLTVPG---csk..............................
C4XZ90_CLAL4/76-213                  ..............................................a-RTSKKLLNLSQSKKKANTQ--.-----PKP.......................................FVLRK..P.ANLSKYDYSVFIDNWTP...................iDEHDLLPPVKESQIKAWESAEKISANIIFDHDmsassd.................afaifdDADKLV..DSsYDEDTcagddp......etsinrGTQDKVTTTQSLILSIPGYTK.................................
Q6BPI0_DEBHA/91-215                  ..............................................s-NVKSKLLNLQSSKKYMTNEKG.TDRAGTQA.......................................FAIRK..P.LDMSTYDYSVFTNYSNEsd................vqDDDCLPPAIKESQVKAWESAEKITNNLIFNDT.............................SSESDD..DD.DADGEp................kGAKETKHRNNEIIQSLPGYTK.................................
G8Y2D8_PICSO/97-208                  ..............................................n-MLKNKLLNLQSSKKYSRKDFD.LAGSGAG-.......................................FLSAN..S.LVSGGYDYGVFVSANDGas................gpEDKSMPPLVKQSQIKAWESAEKVSQKLIFDDS.............................DTEEGE..KE.SSPSE..................----------EIITSIPGYTN.................................
A0A367YIR5_9ASCO/118-239             ...............................................RLVKTKLLNLQQSLKQQLINRI.SEEQPRLGqhhyssd........................nriqfpphFALGK..P.EE-KSFDCGIYTRAVER....................NRNELFPAVRESQIKAWESAERATRNLVFSND.............................SSEDES..DD.DELDN..................-----------AIVSIPGYTQ.................................
A0A1G4MK66_LACFM/40-137              .................................padanafgtpdkdq----------------------.-------A.......................................FM--S..E.KDPDVYDYFPLSNKRL-....................--------LTESRINQLLQSETAAHCLVFHKDkhdeq..................epgyrpDLDIWC..CD.SSDEE..................----IPTSAEHILLSVP----ea...............................
A0A2H0ZL46_CANAR/85-228              .............................................ak--TSKKLLNFQQSKKS------.--QASSQP.......................................FILHK..P.ADLSHFDYSIYTRKPNPvneipaiaiqsssspttlaePPKQLHPPVRQSQIKAWESAENITSNRIFDYTkpg.......................eesW----I..DE.DTYEYgieeev......sidrgtEEWAEPAATDGILVSVP----els..............................
G8BHL7_CANPC/199-266                 ........................................nvqqqkt----------------------.--------.......................................-----..-.-----------------....................HQATTQSELQHSPRKITHDAEYYTRKVIFGND.............................TSDSEI..DD.EENEQ..................-----VEEDASPIRSIPGYTK.................................
A0A1D8PN73_CANAL/122-251             ...............................................RLIKNKLLNLQQSSKQQLINRI.SDKDPRHShsnssqsn.......................akkvtppvFGLQK..V.AS-SPYDFSVFTTVATNe.................kqHDEVLFPAIKQSQIRAWESAEKICRGIIFDDD.............................DDDEEE..ST.DDESE..................-------NTKNPIISIPGYT-e................................
J5RT37_SACK1/57-168                  .....................vleekdvdeaygmnmdvdevdhlnsl----------------------.--------.......................................---SH..I.EEEKAYDYSPFCERNT-....................--------LRESKIDSFLQAERAAHCLVFHKEghldc..................mdtyrpDIDVMC..GE.MTLGS..................--DNPDSNGTMLLESVPGC--sk...............................
#=GC seq_cons                        .....................................................................................................................hh.pp....hs.spYDYssFsppp..............................l+ESpI+uappuE+hspsllFcps.............................D.-.ps..s-.sp.cp.........................tpt.llhSlPGh...................................
//
DBGET integrated database retrieval system