#=GF ID   APOBEC4
#=GF AC   PF18775.7
#=GF DE   APOBEC4
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   Iyer LM
#=GF GA   27.20 27.20;
#=GF TC   27.90 27.20;
#=GF NC   27.00 27.00;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 81514348 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0109
#=GF RN   [1]
#=GF RM   21890906
#=GF RT   Evolution of the deaminase fold and multiple origins of
#=GF RT   eukaryotic editing and mutagenic nucleic acid deaminases from
#=GF RT   bacterial toxin systems.
#=GF RA   Iyer LM, Zhang D, Rogozin IB, Aravind L;
#=GF RL   Nucleic Acids Res. 2011; [Epub ahead of print]
#=GF RN   [2]
#=GF RM   29555751
#=GF RT   Diversification of AID/APOBEC-like deaminases in metazoa:
#=GF RT   multiplicity of clades  and widespread roles in immunity.
#=GF RA   Krishnan A, Iyer LM, Holland SJ, Boehm T, Aravind L;
#=GF RL   Proc Natl Acad Sci U S A. 2018;115:E3201.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A member of the AID/APOBEC family of cytosine deaminases. The
#=GF CC   biological function of APOBEC4 is poorly understood. However, it
#=GF CC   is widely conserved across vertebrates [1].
#=GF SQ   77
#=GS A0A091GQ55_BUCRH/1-65     AC A0A091GQ55.1
#=GS A0A8S3TD72_MYTED/888-967  AC A0A8S3TD72.1
#=GS A0A091WDY6_OPIHO/1-75     AC A0A091WDY6.1
#=GS A0A091G380_9AVES/22-106   AC A0A091G380.1
#=GS A0A8S3QNJ3_MYTED/326-384  AC A0A8S3QNJ3.1
#=GS A0A093I8Y9_STRCA/1-74     AC A0A093I8Y9.1
#=GS A0A091PR75_HALAL/1-65     AC A0A091PR75.1
#=GS A0A7L0M0P5_9PSIT/1-75     AC A0A7L0M0P5.1
#=GS A0A099ZXL0_CHAVO/22-106   AC A0A099ZXL0.1
#=GS A0A094K7N8_ANTCR/1-65     AC A0A094K7N8.1
#=GS A0A8T2PGK6_9TELE/137-221  AC A0A8T2PGK6.1
#=GS A0A093H7N8_GAVST/22-106   AC A0A093H7N8.1
#=GS A0A4W5QAW3_9TELE/102-182  AC A0A4W5QAW3.1
#=GS F6SPN1_CIOIN/83-162       AC F6SPN1.2
#=GS A0A8C7J6S7_ONCKI/109-189  AC A0A8C7J6S7.1
#=GS A0A8B6D3T4_MYTGA/80-163   AC A0A8B6D3T4.1
#=GS A0A091TH63_PHALP/1-65     AC A0A091TH63.1
#=GS A0A8M1KLK9_CLUHA/108-192  AC A0A8M1KLK9.1
#=GS A0A091MHU6_9PASS/1-63     AC A0A091MHU6.1
#=GS A0A8C6JRR8_MELUD/105-174  AC A0A8C6JRR8.2
#=GS A0A7K6U9C9_9AVES/118-202  AC A0A7K6U9C9.1
#=GS A0A8J7P4L1_ATRSP/327-411  AC A0A8J7P4L1.1
#=GS A0A091ETZ4_CORBR/1-64     AC A0A091ETZ4.1
#=GS A0A091UXU5_NIPNI/21-105   AC A0A091UXU5.1
#=GS A0A093ITV6_FULGA/22-106   AC A0A093ITV6.1
#=GS A0A087QNJ4_APTFO/1-65     AC A0A087QNJ4.1
#=GS A0A099ZZR5_CHAVO/1-65     AC A0A099ZZR5.1
#=GS A0A091V1W3_PHORB/1-65     AC A0A091V1W3.1
#=GS W5MW91_LEPOC/15-99        AC W5MW91.1
#=GS A0A093QYH8_PHACA/1-65     AC A0A093QYH8.1
#=GS A0A2B4SME3_STYPI/91-177   AC A0A2B4SME3.1
#=GS A0A8C8J7H9_ONCTS/114-194  AC A0A8C8J7H9.1
#=GS A0A7L4MX43_9AVES/47-131   AC A0A7L4MX43.1
#=GS A0A091WIF8_OPIHO/22-106   AC A0A091WIF8.1
#=GS A0A662YLK0_ACIRT/104-188  AC A0A662YLK0.1
#=GS A0A8S3YXE9_9EUPU/77-173   AC A0A8S3YXE9.1
#=GS K7G211_PELSI/212-285      AC K7G211.1
#=GS A0A6J2W7P4_CHACN/100-179  AC A0A6J2W7P4.1
#=GS A0A8B6FU50_MYTGA/95-185   AC A0A8B6FU50.1
#=GS A0A093HKT8_STRCA/22-106   AC A0A093HKT8.1
#=GS A0A091V9F4_NIPNI/1-65     AC A0A091V9F4.1
#=GS A0A6J1U8W3_9SAUR/1-49     AC A0A6J1U8W3.1
#=GS A0A091G853_9AVES/1-70     AC A0A091G853.1
#=GS F6S0S9_CIOIN/277-366      AC F6S0S9.2
#=GS A0A091KLV2_9GRUI/22-106   AC A0A091KLV2.1
#=GS A0A093J6I5_FULGA/1-65     AC A0A093J6I5.1
#=GS A0A093DVS1_9AVES/22-85    AC A0A093DVS1.1
#=GS A0A094LAG0_PODCR/1-65     AC A0A094LAG0.1
#=GS A0A093NRV6_PYGAD/22-106   AC A0A093NRV6.1
#=GS A0A850ZI65_9PASS/2-76     AC A0A850ZI65.1
#=GS A0A7L4DXU1_HIRRU/2-76     AC A0A7L4DXU1.1
#=GS A0A8U1EPI6_SALNM/129-209  AC A0A8U1EPI6.1
#=GS A0A8D0F1P8_STROC/123-205  AC A0A8D0F1P8.1
#=GS A0A087VRL2_BALRE/2-66     AC A0A087VRL2.1
#=GS A0A093JP51_EURHL/1-65     AC A0A093JP51.1
#=GS A0A091PTE0_LEPDC/1-75     AC A0A091PTE0.1
#=GS A0A5N4CNS0_CAMDR/22-106   AC A0A5N4CNS0.1
#=GS A0A099Z1L5_TINGU/22-106   AC A0A099Z1L5.1
#=GS A0A1U7S0S1_ALLSI/79-152   AC A0A1U7S0S1.1
#=GS A0A091UXX9_PHALP/22-106   AC A0A091UXX9.1
#=GS A0A8C7J821_ONCKI/109-189  AC A0A8C7J821.1
#=GS K7G211_PELSI/24-97        AC K7G211.1
#=GS A0A091RWG2_NESNO/1-65     AC A0A091RWG2.1
#=GS A0A3M6T8U8_POCDA/75-160   AC A0A3M6T8U8.1
#=GS A0A091IKM1_CALAN/1-70     AC A0A091IKM1.1
#=GS A0A093F6R6_GAVST/1-70     AC A0A093F6R6.1
#=GS A0A6F9ALQ4_9TELE/132-212  AC A0A6F9ALQ4.1
#=GS A0A093R3S3_PYGAD/1-65     AC A0A093R3S3.1
#=GS A0A093CT04_TAUER/1-65     AC A0A093CT04.1
#=GS A0A091Q6M3_LEPDC/22-106   AC A0A091Q6M3.1
#=GS A0A091R868_9GRUI/1-65     AC A0A091R868.1
#=GS A0A091LC91_CATAU/22-106   AC A0A091LC91.1
#=GS A0A091QH63_MERNU/1-65     AC A0A091QH63.1
#=GS A0A087QVF4_APTFO/22-106   AC A0A087QVF4.1
#=GS A0A8S3R9P8_MYTED/325-383  AC A0A8S3R9P8.1
#=GS A0A1S3T3Q2_SALSA/94-170   AC A0A1S3T3Q2.1
#=GS A0A091KXU3_COLST/22-106   AC A0A091KXU3.1
A0A091GQ55_BUCRH/1-65                ....................ITWYL..SWSP..CAD....C.CCKIVN.FL..................KKHS....YV.N.MR...IYVARLYYPE......................YET..NR..RGLKNLRN.LA....eVPIA.VM...........E....I.....-...........----------e................................
A0A8S3TD72_MYTED/888-967             ...........iianesppf-----..--SF..SNA....F.CDLIAS.FK..................EAEK....TV.E.VQ...LKIVRLKNIEew.................edeYED..NR..DGLRYLHS.TG.....IMLS.PV...........S....G.....K...........DWGYL-----rqil.............................
A0A091WDY6_OPIHO/1-75                ....................ITWYL..SWSP..CAN....C.CRKILN.FL..................KKHS....YV.N.ID...IRVARLYYIQ......................VER..NL..QGLKKLES.LA....nVTIG.VM...........K....I.....K...........DYTDCWKIFI.................................
A0A091G380_9AVES/22-106              ....................IILYS..SYSP..CNEvphcC.VSKIYN.FS..................LKYP....EI.T.LC...IYFSQLYHTQag.................cpsAAW..NR..EALRSLWS.LWp...rVTLQ.RP...........P....G.....E...........LWPSLLCPFV.................................
A0A8S3QNJ3_MYTED/326-384             ...........nkqiaglrm-----..----..---....-.------.--..................---T....DI.N.FQ...IIFSNFYLHR......................DEK..NR..EGLINLSR.NN.....IKLD.IL...........T....G.....E...........KWKYFYMAI-l................................
A0A093I8Y9_STRCA/1-74                ....................ITLYL..SWSP..CRN....C.CYEMQY.FL..................KKHP....NV.N.IC...IYLARLYYTE......................DEE..IC..KALKDLSE.KK.....VIIS.VM...........K....I.....E...........DYIYCWKTFV.................................
A0A091PR75_HALAL/1-65                ....................ITWYL..SWSP..CAD....C.CHKILK.FL..................KKHS....NV.N.ID...IHVARVYYAE......................DEK..VR..QGLKNLVS.LA....kVTIA.VM...........E....T.....-...........----------k................................
A0A7L0M0P5_9PSIT/1-75                ....................ITWYL..SWSP..CAK....C.CRKILN.FL..................KKHS....YV.S.IK...IHVARLFRID......................DKE..TR..QNLKNLGS.LV....gVTVS.VM...........E....I.....K...........DYTNCWKTFI.................................
A0A099ZXL0_CHAVO/22-106              ....................IIVYS..NYSP..CNEayhcC.VSKIYN.FL..................LRYP....EI.T.LC...IYFSKLYHTEdr.................fptSVW..NR..EALRSLSS.LWp...qVTLQ.RL...........P....G.....G...........AWHYLLCNFV.................................
A0A094K7N8_ANTCR/1-65                ....................ITWYL..SWSP..CAN....C.CRKIRN.FL..................KKHS....YV.Y.ID...IYVARLYYID......................DEE..NR..RGLRNLQS.LD....eVTIA.VM...........E....I.....E...........----------.................................
A0A8T2PGK6_9TELE/137-221             ....................IMLYS..NYTP..CEEapslC.ASTTAH.FL..................AQHP....WV.R.LD...LLFSQLYHTDds.................wpcSPQ..NQ..GGLRILAG.LWp...rVTLS.PL...........S....G.....G...........AWAQLQRKFV.................................
A0A093H7N8_GAVST/22-106              ....................IILYA..NYSP..CNEayhcC.VSKIYN.FL..................LKYP....EI.T.LC...IYFSRLYHTEdh.................fptAVW..NR..EALRSLSS.LWp...rVTLQ.RL...........P....G.....G...........ARQYLLCNFV.................................
A0A4W5QAW3_9TELE/102-182             ....................IMLYC..NYTP..CQE....C.SQTLIS.FL..................LHYP....WV.R.QD...LLFSQLYHTAps.................qthSLD..NQ..TGLRSLAA.LWp...rLTLS.PI...........S....G.....A...........AWGHLLRCFV.................................
F6SPN1_CIOIN/83-162                  ..................vt--VELmsSRSP..SNA....G.AEQLQG.FLe...............ycKKHS...iKV.N.IN...FSFVQPFSWD......................NKF..NR..EGLHNLYE.KG.....VKLK.IL...........S....F.....Q...........QVINCMMGD-l................................
A0A8C7J6S7_ONCKI/109-189             ....................IILYC..NYTP..CQE....C.SQTLIS.FL..................LHYP....WV.R.LD...LLFSQLYHTAps.................qthSLD..NQ..TGLRSLAA.LWp...rLTLS.PI...........S....G.....A...........AWGHLLRCFV.................................
A0A8B6D3T4_MYTGA/80-163              ........leleiianespp-----..-FSF..SNA....F.CDLIAS.FK..................EAEK....TV.E.VQ...LKIVRLKNIEew.................edeYED..NR..DGLRYLHS.TG.....IMLS.PV...........S....G.....K...........DWGYL-----rqil.............................
A0A091TH63_PHALP/1-65                ....................ITWYL..SWSP..CAD....C.CHKILN.FL..................KKHS....NV.N.II...IYVARLYYKE......................DEK..IR..QGLKNLVN.LA....gITIA.VM...........E....I.....E...........----------.................................
A0A8M1KLK9_CLUHA/108-192             ...................v-RLYS..SSSP..CEDpgsqC.CGLLLA.FL..................QQRP....WL.R.LD...LLFSQLHRTQpr.................wpqAPR..TR..EALRSLAA.LWp...rVTLS.PL...........S....G.....R...........VWALLLGSFV.................................
A0A091MHU6_9PASS/1-63                ....................ITWYL..SWSP..CVN....C.CYKIRD.FL..................NRHS....YV.T.IR...IYVARLCYRG......................FHR..NR..KGLRNLVS.LR....eVTVN.VM...........-....-.....-...........----------e................................
A0A8C6JRR8_MELUD/105-174             .................val-----..---P..YRC....C.VSKIYN.FS..................LKYQ....EV.T.LS...IYFSQLYYTEdg.................fptAMW..NR..EALGSLSS.LWp...lVTLQ.RL...........-....-.....-...........----------lggrgst..........................
A0A7K6U9C9_9AVES/118-202             ....................IILYS..NYSP..CNEaphcC.ISKIYR.FL..................LKHP....AI.T.LC...LYFSQLYHTEdg.................fptAAW..NR..GALRSLSS.LWp...qVTLQ.GL...........P....G.....R...........TWHHLLGNFV.................................
A0A8J7P4L1_ATRSP/327-411             ....................VTLYS..NYTP..CEEppsrC.ASALTH.FL..................QAHP....AL.R.LD...LLFSQLYHTEdw.................hpyGSA..NR..QALRALGA.LWp...rLTLS.PI...........S....G.....G...........WWLSLLRKFV.................................
A0A091ETZ4_CORBR/1-64                ....................ITWYL..SWSP..CMT....C.CYIIRN.FL..................VRHP....NV.N.IE...IHVARLYNTR......................WAG..TR..RGLRELAR.LRg...rVTID.VM...........-....-.....-...........----------e................................
A0A091UXU5_NIPNI/21-105              ....................IILYS..NYSP..CNEayhcC.ISKIYN.FL..................LKYP....EI.T.LC...IYFSQLYHTEdg.................fptAAW..NR..EALRSLSS.LWp...rVTLQ.RL...........P....G.....G...........TWRYLLCNFV.................................
A0A093ITV6_FULGA/22-106              ....................IILYS..NYSP..CNEayhyC.ISKIYN.FL..................LKYP....EI.T.LC...IYFSQFYHTEdg.................fptAAW..NR..EALRSLSS.LWp...rVTLQ.RL...........P....G.....G...........ARRYLLRNFV.................................
A0A087QNJ4_APTFO/1-65                ....................ITWYL..SWSP..CAD....C.CRKILN.FL..................KKNS....NV.N.ID...IYVARLYYTE......................DEK..IR..QGLQNLVS.LA....eVTIA.VM...........E....T.....-...........----------e................................
A0A099ZZR5_CHAVO/1-65                ....................ITWYL..SWSP..CAE....C.CLKILN.FL..................EENS....NV.N.ID...IHIARLYRIQ......................DER..NR..QGLRELVS.SE....eVTIA.VM...........G....I.....-...........----------e................................
A0A091V1W3_PHORB/1-65                ....................ITWYL..SWSP..CAK....C.CYEILN.FL..................KKHP....NV.N.ID...IYVARLYDIE......................KEK..TR..QGLKNLVR.LP....eVTIA.VM...........E....M.....-...........----------e................................
W5MW91_LEPOC/15-99                   ....................VTLYS..NYTP..CEEppgrC.ASALTH.FL..................QAHP....AL.R.LD...LLFSQLYHTEdw.................hpyGSA..NR..QALRALGA.LWp...rLTLS.PI...........S....G.....G...........WWLSLLRKFV.................................
A0A093QYH8_PHACA/1-65                ....................ITWYL..SWSP..CEE....C.CCKILN.FL..................KKHS....NV.S.IC...IYVARLYHIE......................DEK..IR..QGLKNLVN.FT....kVTVA.VM...........G....I.....-...........----------e................................
A0A2B4SME3_STYPI/91-177              ..........ltgflhdfql---LS..NFSP..CGE....C.SEKICE.WL..................AQNE....SV.S.VS...IRFAHLHNIHvrv................qkvAED..NA..IGLRKLVE.KG.....VQLK.AL...........S....D.....Y...........DWLQLLMI--dr...............................
A0A8C8J7H9_ONCTS/114-194             ....................IILYC..NYTP..CQE....C.SQTLIS.FL..................LHYP....WV.R.LD...LLFSQLYHTAps.................qthSLD..NQ..TGLRSLAA.LWp...rLTLS.PI...........S....G.....A...........AWGHLLRCFV.................................
A0A7L4MX43_9AVES/47-131              ....................ITLYS..NYSP..CNEayhcC.ISQIYN.FV..................LKHP....QI.T.LC...IYFSQLYHTEdg.................cptAAW..NR..EALRSLSS.LWp...wVTLR.RL...........P....G.....G...........SQPYLLSNFV.................................
A0A091WIF8_OPIHO/22-106              ....................IILYA..NYSP..CNEayhcC.ISKIYN.FL..................LKYP....EI.T.LC...IYFSRLYHTEdg.................fptATW..NQ..EALRSLSS.LWp...rVTLQ.RL...........P....A.....G...........TQHYLLLNFV.................................
A0A662YLK0_ACIRT/104-188             ....................VTLYC..SHTP..CNEpgsaC.LSDTAG.FL..................EDFP....GT.R.LD...LYFSQLYHTDer.................hpaSGW..NR..EGLRALAG.LWp...rVTLS.PL...........S....G.....G...........GWLSLLRKFV.................................
A0A8S3YXE9_9EUPU/77-173              ...................a-TLIQ..NFSP..CFE....C.AEEIIK.TVa...............laKEKR...iKF.E.IS...IAFVALNRIRrpswiwrgme..dcfhgipvneSND..NV..IGLRQLQE.SG.....VKLV.TF...........S....P.....N...........LWSFLF----tfl..............................
K7G211_PELSI/212-285                 ....................VTWFL..SWSP..CWK....C.SQSVVE.FR..................KAYP....KV.N.LE...IYVARLFRHE......................EEC..NR..QGLRDLVM.NG.....VTIR.VM...........N....L.....S...........AYNYCWRTFV.................................
A0A6J2W7P4_CHACN/100-179             ....................ILLYS..NYTP..CMEppnwC.VDSVLN.FL..................ERHP....WI.R.LD...LFFSQLHNPQ......................NPQ..NQ..AGLRSLAS.LWp...rVTLS.PL...........S....G.....N...........AWGALIRRFV.................................
A0A8B6FU50_MYTGA/95-185              ..................ie--VIL..SYSP..CRN....C.SDALCK.FKeelygeknkgssgfptdlEKGE....AT.E.FK...ITFSNFFCHD......................DLE..NQ..GGLKNLLK.GG.....IKLD.IF...........T....D.....E...........NWKYFF----nvt..............................
A0A093HKT8_STRCA/22-106              ....................IILYS..NYSP..CNEadhcC.ISKIYN.FL..................IKHP....EV.T.LC...IYFSQLYHTEds.................fptAMW..NR..EALRSLSS.LWp...hVTLY.PL...........S....G.....G...........IRHYLLCNFV.................................
A0A091V9F4_NIPNI/1-65                ....................ITWYL..SRSP..CAK....C.CYEILD.FL..................NKHS....NV.N.ID...IYIAQLYKIK......................NEE..NC..QGLRNLVS.LA....kVTIA.VM...........E....I.....E...........----------.................................
A0A6J1U8W3_9SAUR/1-49                ..................my-----..----..---....-.------.--..................----....--.-.--...----QLYHTEed.................fpmSTW..NC..EALRSLAS.MWp...qVTLN.PL...........C....G.....G...........LWHSLLYNFV.................................
A0A091G853_9AVES/1-70                ....................ITWFL..SWSP..CAD....C.CRKIMD.FL..................MKHS....YV.N.ID...IRVARLYFIE......................DPK..IR..QGLKNLVS.LA....gVNIA.VM...........E....I.....K...........----------gkvfc............................
F6S0S9_CIOIN/277-366                 ................vdiv----M..SSSP..IHQ....C.SETLLN.LVqle...........ktflKHRNf.dgQL.N.VT...IRFAHSYGWDvkd................dviRER..VH..TGLRNLFK.EG.....VNLE.IM...........S....A.....D...........IILDE-----lrvdd............................
A0A091KLV2_9GRUI/22-106              ....................IILYS..NYSP..CNEahhcC.VSKIYN.FL..................LKYP....EI.R.LC...IYFSQLYHTEdg.................fptAVW..NR..EALRSLSS.LWp...rVILQ.RL...........P....G.....G...........MWHYLLCNFV.................................
A0A093J6I5_FULGA/1-65                ....................ITWYL..SWSP..CAK....C.CRKILN.FL..................KMHS....NV.K.ID...IYVARLYYIE......................DEK..NR..QGLKKLVS.LA....gVKIA.VM...........E....I.....E...........----------.................................
A0A093DVS1_9AVES/22-85               ....................IILYS..NFLP..CNEayhcC.ISNIYN.FL..................LKYP....EI.T.LC...IYFSQLYHTQdt.................fcaTTW..NR..KALQSFSS.--.....----.--...........-....-.....-...........----------en...............................
A0A094LAG0_PODCR/1-65                ....................ITWFL..SWSP..CAN....C.CHKILN.FL..................KKHS....NV.N.ID...IYVARLFHIE......................DEK..NR..QGLKNLVS.LA....kVTIA.VM...........E....T.....-...........----------e................................
A0A093NRV6_PYGAD/22-106              ....................IILYS..NYSP..CNEayhcC.ISKIYN.FL..................LKYP....EI.T.LC...IYFAQLYHTEdg.................fptAAW..NR..EALRSLSS.LWp...rVTLQ.RL...........P....A.....G...........AQRYLLCNFV.................................
A0A850ZI65_9PASS/2-76                ....................ITWYL..SWSP..CWS....C.CDIIQD.FL..................ERQP....NV.D.ID...IRVARLYYPH......................DAR..NR..RGLRELAS.LQ....gVTIQ.VM...........E....K.....E...........DYRYCWETFV.................................
A0A7L4DXU1_HIRRU/2-76                ....................ITLYL..SWSP..CCT....C.CSKIRD.FL..................KRNP....NV.K.ID...IRVARLIYPD......................YAE..TR..SSLRELNG.LQ....rVSIQ.VM...........E....A.....A...........DYSYCWETFI.................................
A0A8U1EPI6_SALNM/129-209             ....................IILYC..NYTP..CQE....C.SQTLIS.FL..................LHYP....WV.R.LD...LLFSQLYHTAps.................qthSLD..NQ..TGLRSLAA.LWp...rLTLS.PI...........S....G.....A...........AWGHLLRCFV.................................
A0A8D0F1P8_STROC/123-205             ...................f-ILCS..NYSP..CNEayhcC.VSKIYN.FL..................WKYP....EI.T.LC...IYFSRLYHTEdg.................fptAAW..NR..EALRSLSS.LW.....VTLQ.RL...........P....G.....G...........ARCYLLCNFV.................................
A0A087VRL2_BALRE/2-66                ....................ITWYL..SWSP..CAD....C.CHKILN.FL..................KRHS....NV.N.ID...IYVARLYYIE......................DEE..IR..QCLKNLVS.LA....eVTIA.VM...........K....I.....E...........----------.................................
A0A093JP51_EURHL/1-65                ....................ITWYL..SWSP..CAH....C.CRKILN.FL..................KRHS....DV.N.IH...IYIARLYYIE......................NEE..IR..QGLKNLVS.LE....aVKIA.VM...........E....T.....-...........----------e................................
A0A091PTE0_LEPDC/1-75                ....................VTWYL..SWSP..CVN....C.CRKILN.FL..................KKHS....NV.N.ID...MHVARLYYIE......................DER..IR..QGLKNLVS.LA....kVTIA.VM...........E....I.....E...........DYTYCWKNFI.................................
A0A5N4CNS0_CAMDR/22-106              ....................IILYS..NNSP..CDEanhcC.TSKMYN.FL..................TMYP....DV.T.LS...IYFSQLYHTEte.................fpaSAW..NR..EALRSLAS.LWp...qVTVS.PV...........S....G.....G...........VWHSLLNSFV.................................
A0A099Z1L5_TINGU/22-106              ....................IILYS..NYSP..CNEadhcC.LSKIYS.FL..................TKYP....QV.T.LC...IYFSKLYHIEns.................lptAVW..NH..EVLKSLSS.LWp...hVTLH.PL...........C....G.....G...........IWHYLLCNFV.................................
A0A1U7S0S1_ALLSI/79-152              ....................VTWYL..SWSP..CAD....C.ASKIVK.FL..................KKYP....YL.K.LT...IYVAQLYYHT......................EEE..NR..KGLRLLRS.KK.....VIIR.VM...........D....I.....A...........DYNYCWKVFV.................................
A0A091UXX9_PHALP/22-106              ....................IILYS..NYSP..CNEahhfC.ISKIYN.FL..................LKYP....EI.A.LC...IYFSQLYHTEdg.................fpsAAW..NR..EALRSLSS.LWp...rVTLQ.RL...........P....G.....G...........TWRYLLCNFV.................................
A0A8C7J821_ONCKI/109-189             ....................IILYC..NYTP..CQE....C.SQTLIS.FL..................LHYP....WV.R.LD...LLFSQLYHTAps.................qthSLD..NQ..TGLRSLAA.LWp...rLTLS.PI...........S....G.....A...........AWGHLLRCFV.................................
K7G211_PELSI/24-97                   ....................LTWYM..TWSP..CGE....C.CKAIRD.FL..................KEQP....NV.N.LV...IYVARIYCHE......................EEN..NR..QGLRSLVN.IG.....VTIR.IM...........D....L.....P...........VYSYCWRTFV.................................
A0A091RWG2_NESNO/1-65                ....................ITWYL..SWSP..CVN....C.CRKILK.FL..................KQHS....YV.N.IK...IYVARLYYID......................DDE..IR..QNLKNLVS.LV....dVTIA.VM...........D....I.....E...........----------.................................
A0A3M6T8U8_POCDA/75-160              ............tgflhdlq--LLS..NFSP..CGE....C.SEKICG.WL..................AQND....SV.S.VS...IRFAHLHNIHvrv................qkvAED..NA..IGLRKLVE.KG.....VQLK.AL...........S....D.....Y...........DWLQLLMI--dr...............................
A0A091IKM1_CALAN/1-70                ....................ITWYL..SWSP..CAC....C.CCKIQD.FL..................KMNS....YV.N.TD...IDVAQLYGNY......................QEQ..NC..QGLKNLKS.LA....rVTIA.VM...........R....I.....E...........DKISC-----.................................
A0A093F6R6_GAVST/1-70                ....................ITWYL..SWSP..CAN....C.CRKILR.FL..................RKHS....NV.N.ID...IHVARLYYIE......................DEN..IR..QGLKSLVN.LA....eVTIA.VM...........E....I.....E...........----------gkvfc............................
A0A6F9ALQ4_9TELE/132-212             ....................IMLYC..NYTP..CQE....C.CQTMAS.FL..................LRYP....WM.R.LD...VLFSQLYHTAps.................qpySLD..NQ..TGLRSLAA.LWp...rLTLS.PI...........S....G.....A...........AWGHLLRCFV.................................
A0A093R3S3_PYGAD/1-65                ....................ITWYL..SWSP..CAD....C.CRKILN.FL..................KKNS....NV.N.ID...IYVARLYYIE......................DEK..IR..QGLQNLVS.LA....eVTIA.VM...........E....T.....-...........----------e................................
A0A093CT04_TAUER/1-65                ....................ITWYL..SWSP..CAR....C.CYKILD.FL..................KEHS....YV.N.LH...IYVARLYCIE......................DEK..TR..RGLKKLNS.LE....gVTIA.VM...........E....-.....-...........----------ee...............................
A0A091Q6M3_LEPDC/22-106              ....................IILYS..NYSP..CNEayhcC.ISKIYN.FL..................LKYQ....EI.I.LR...IYFSQLYHTEdc.................fptAAW..NC..RALWSLSS.LWp...rVTLQ.RL...........P....G.....G...........AWHYLLCNFV.................................
A0A091R868_9GRUI/1-65                ....................ITWYL..SWSP..CAN....C.CYEIVD.FL..................QRHS....YV.N.IK...IFVARLYYID......................RER..NR..QGLRDLMN.SA....gVTID.VM...........D....I.....E...........----------.................................
A0A091LC91_CATAU/22-106              ....................IILYS..NYSP..CNEayhcC.VSKIYN.FL..................LKYP....EI.T.LC...IYFSQLYHTEdg.................fptAAW..NR..EALRSLSS.LWp...rVTLQ.RL...........P....G.....G...........AWRYLLCNFV.................................
A0A091QH63_MERNU/1-65                ....................ITWYL..SWSP..CAN....C.CYRIVQ.FL..................MKHS....YV.S.ID...IRVARLYFIE......................DET..TR..QGLEELVS.CA....rVRLT.VM...........D....T.....-...........----------e................................
A0A087QVF4_APTFO/22-106              ....................IILYS..TYSP..CNEayhcC.ISKIYN.FL..................LKYP....EI.T.LC...IYFSQLYHTEdg.................sptAAW..NR..EALRSLSS.LWp...rVTLQ.RL...........P....A.....G...........AQRYLLCNFV.................................
A0A8S3R9P8_MYTED/325-383             ...........nkqiaglrm-----..----..---....-.------.--..................---T....DI.N.FQ...IIFSNFYLHR......................DEK..NR..EGLINLSR.NN.....IKLD.IL...........T....G.....E...........KWKYFYMAI-l................................
A0A1S3T3Q2_SALSA/94-170              ...................e-VLYS..NYMP..CQE....C.SQTLIS.FL..................LRYP....WV.R.LD...LLFSQLYHTAps.................qthSLD..NQ..TGLRSLAV.--.....LTLS.PN...........S....G.....A...........AWGHLLRCFV.................................
A0A091KXU3_COLST/22-106              ....................IILFS..NYSP..CNEayhcC.VSKIYN.FL..................LKYP....EI.T.LC...IYFSQLYHIQdr.................sphAWW..NR..EALRSLSS.LWp...rVTLQ.RL...........P....G.....G...........AWPYLLCHFV.................................
#=GC seq_cons                        ....................IhhY...saSP..Cs-....C.spcIhs.FL..................h+as....pV.s.ls...IahupLYah-......................stp..NR..pGLRsLsu.Lh....pVTls.sh...........s....s.....t............h..hh.....................................
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