GenomeNet

Database: Pfam
Entry: Acetyltransf_14
LinkDB: Acetyltransf_14
Original site: Acetyltransf_14 
#=GF ID   Acetyltransf_14
#=GF AC   PF03421.17
#=GF DE   YopJ Serine/Threonine acetyltransferase
#=GF PI   Peptidase_C55; YopJ;
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF SE   Bateman A
#=GF GA   22.60 22.60;
#=GF TC   22.60 22.60;
#=GF NC   22.50 22.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16728640
#=GF RT   Yersinia YopJ acetylates and inhibits kinase activation by
#=GF RT   blocking phosphorylation. 
#=GF RA   Mukherjee S, Keitany G, Li Y, Wang Y, Ball HL, Goldsmith EJ,
#=GF RA   Orth K; 
#=GF RL   Science. 2006;312:1211-1214.
#=GF RN   [2]
#=GF RM   12433923
#=GF RT   Yersinia effector YopJ inhibits yeast MAPK signaling pathways by
#=GF RT   an evolutionarily conserved mechanism. 
#=GF RA   Yoon S, Liu Z, Eyobo Y, Orth K; 
#=GF RL   J Biol Chem. 2003;278:2131-2135.
#=GF RN   [3]
#=GF RM   17116858
#=GF RT   Acetylation of MEK2 and I kappa B kinase (IKK) activation loop
#=GF RT   residues by YopJ inhibits signaling.
#=GF RA   Mittal R, Peak-Chew SY, McMahon HT;
#=GF RL   Proc Natl Acad Sci U S A. 2006;103:18574-18579.
#=GF RN   [4]
#=GF RM   20430892
#=GF RT   The acetyltransferase activity of the bacterial toxin YopJ of
#=GF RT   Yersinia is activated by eukaryotic host cell inositol
#=GF RT   hexakisphosphate.
#=GF RA   Mittal R, Peak-Chew SY, Sade RS, Vallis Y, McMahon HT;
#=GF RL   J Biol Chem. 2010; [Epub ahead of print]
#=GF RN   [5]
#=GF RM   22802624
#=GF RT   Serine/threonine acetylation of TGFbeta-activated kinase (TAK1)
#=GF RT   by Yersinia pestis YopJ inhibits innate immune signaling.
#=GF RA   Paquette N, Conlon J, Sweet C, Rus F, Wilson L, Pereira A,
#=GF RA   Rosadini CV, Goutagny N, Weber AN, Lane WS, Shaffer SA, Maniatis
#=GF RA   S, Fitzgerald KA, Stuart L, Silverman N;
#=GF RL   Proc Natl Acad Sci U S A. 2012;109:12710-12715.
#=GF DR   INTERPRO; IPR005083;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The Yersinia effector YopJ inhibits the innate immune response
#=GF CC   by blocking MAP kinase and NFkappaB signaling pathways.  YopJ is
#=GF CC   a serine/threonine acetyltransferase which regulates signalling
#=GF CC   pathways by blocking phosphorylation [1][2].  Specifically, YopJ
#=GF CC   has been shown to block phosphorylation of active site residues
#=GF CC   [3].  It has also been shown that YopJ acetyltransferase is
#=GF CC   activated by eukaryotic host cell inositol hexakisphosphate [4].
#=GF CC   This family was previously incorrectly annotated in Pfam as
#=GF CC   being a peptidase family.
#=GF SQ   52
#=GS Q8Y2L4_RALSO/91-283       AC Q8Y2L4.1
#=GS A0A0Q9YD96_9COXI/202-358  AC A0A0Q9YD96.1
#=GS A0A378I794_9GAMM/28-169   AC A0A378I794.1
#=GS A0A1Y6ITH2_9VIBR/146-320  AC A0A1Y6ITH2.1
#=GS A0A418X4N1_9BURK/113-285  AC A0A418X4N1.1
#=GS A0A068QW43_9GAMM/4-172    AC A0A068QW43.1
#=GS G6YIH2_9RHIZ/1-161        AC G6YIH2.1
#=GS E9CMN8_9GAMM/46-225       AC E9CMN8.1
#=GS A0A0G3EL98_9BURK/1-39     AC A0A0G3EL98.1
#=GS W1IPC6_9GAMM/5-173        AC W1IPC6.1
#=GS Q8Y164_RALSO/86-256       AC Q8Y164.1
#=GS A0A1H2PNN8_9BURK/55-227   AC A0A1H2PNN8.1
#=GS A0A014PYK8_9GAMM/69-245   AC A0A014PYK8.1
#=GS A0A0G3ER55_9BURK/111-216  AC A0A0G3ER55.1
#=GS Q8XXI2_RALSO/155-342      AC Q8XXI2.2
#=GS A0A0M2KAV7_9GAMM/155-327  AC A0A0M2KAV7.1
#=GS A0A328Z5E4_9BURK/71-262   AC A0A328Z5E4.1
#=GS Q8Y2L4_RALSO/386-577      AC Q8Y2L4.1
#=GS A0A0F5JSW9_9BURK/60-236   AC A0A0F5JSW9.1
#=GS Q87GH0_VIBPA/21-193       AC Q87GH0.1
#=GS A0A078L0R4_9GAMM/3-159    AC A0A078L0R4.1
#=GS A0A370MZA9_9BURK/191-374  AC A0A370MZA9.1
#=GS A0A0Q6XHS1_9BURK/11-197   AC A0A0Q6XHS1.1
#=GS A0A2S0PDD2_9NEIS/267-438  AC A0A2S0PDD2.1
#=GS A0A366I3T8_9GAMM/1-167    AC A0A366I3T8.1
#=GS Q9RI13_YERPE/26-198       AC Q9RI13.1
#=GS A0A0Q6XCB2_9BURK/393-581  AC A0A0Q6XCB2.1
#=GS A0A2G8DX34_9GAMM/26-198   AC A0A2G8DX34.1
#=GS A0A1Y6ITH3_9VIBR/59-225   AC A0A1Y6ITH3.1
#=GS A0A0G9HUJ3_9XANT/1-61     AC A0A0G9HUJ3.1
#=GS Q8ZMI3_SALTY/40-212       AC Q8ZMI3.1
#=GS A0A0F5JTZ7_9BURK/1-170    AC A0A0F5JTZ7.1
#=GS F2JZ26_MARM1/145-319      AC F2JZ26.1
#=GS A0A1C3TNN7_XANCT/50-221   AC A0A1C3TNN7.1
#=GS A1TQP0_ACIAC/91-261       AC A1TQP0.1
#=GS A0A0G4JVB0_9GAMM/75-250   AC A0A0G4JVB0.1
#=GS A1TST1_ACIAC/147-332      AC A1TST1.1
#=GS A0A0Q6VWW2_9BURK/57-238   AC A0A0Q6VWW2.1
#=GS A0A078KYG8_9GAMM/7-168    AC A0A078KYG8.1
#=GS A0A0Q8PB81_9BURK/18-198   AC A0A0Q8PB81.1
#=GS A1TP56_ACIAC/85-258       AC A1TP56.1
#=GS B2VJH3_ERWT9/142-315      AC B2VJH3.1
#=GS A0A1H2PNL8_9BURK/49-221   AC A0A1H2PNL8.1
#=GS A0A3S4G8F4_SALBN/25-197   AC A0A3S4G8F4.1
#=GS A0A0G4JW18_9GAMM/87-255   AC A0A0G4JW18.1
#=GS A0A0Q6XCB2_9BURK/94-286   AC A0A0Q6XCB2.1
#=GS Q8P4H6_XANCP/1-140        AC Q8P4H6.1
#=GS Q8Y125_RALSO/174-347      AC Q8Y125.2
#=GS W3U0J6_BARQI/51-223       AC W3U0J6.1
#=GS Y4LO_SINFN/42-211         AC P55555.1
#=GS A0A328ZTJ4_9BURK/55-231   AC A0A328ZTJ4.1
#=GS Q1MTJ6_RALSO/1-95         AC Q1MTJ6.1
Q8Y2L4_RALSO/91-283                  ...............................ESMRQYLAELKTAAHADPN.LRVETPGHrDAEFLDLLVAVENARHPKLALS.A..Htisl.........ntlnTTN.PAAVASLARN.LE.TSMRSREp........whAVVDI...GG..---.....HAMALSVRHH.....PEq....pKQISMIVVNSAgeh.lsvPEWNLMATLLAG.H.L.NHKLEQAG.....D.P..K....GVRIVLHCLNT..GIQKTNHGGAIFALS-AVKAM....PG.DEDIGKLHAH--al..........
A0A0Q9YD96_9COXI/202-358             ......................nhhgcqlfa-------------------.--------.--EDMNVFVEQKNARHQKLGGP.F..HgkvicsqtpsslalldpIAF.DTLSQDIQDI.QT.GFKPRTQ...........FYIYA...NV..NFS.....HCMALDIERE.....ED......GTLHILSFDSA.......--QHIAQYYLL-.-.-.-EKLTAFL.....E.K..N....KINFKITACQS..GLQRSMINCEIFS--------....--.------------hlflqdsakvr.
A0A378I794_9GAMM/28-169              ......dgitiilhefnkanptkppirlidr-------------------.--------.----------------------.-..-.................---.QHILDEIKKE.IA.KNPAEARn........qqFIVKI...DE..---.....HYCVVDLEID.....EQ......GNFQALVLDAA.......--NDLRFLDLVE.D.I.SSLAGLNK.....L.Y..L....V---TGITSKH..NIHKDSISCPIFAISHALALN....E-.------------tplfkhleqeqv
A0A1Y6ITH2_9VIBR/146-320             ..............................p-DLHQYAQQTISRIQKGRE.PNSAITTL.DAKLLPLLAEAENHRHPGLNLH.T..F.................TDQ.NSCYEAIKAQ.QK.TVQETKQpq.......qmRVVYP...PL..PGMa...qHHIALDIRFK.....PG......HQPSILGFESA.......------LSTLA-.-.-.TEPIKNVL.....S.Q..A....FPKAKIQIVDH..SIQNSSWDCVMFSLNNALKAY....KShEEYTDKIHNQ--aq..........
A0A418X4N1_9BURK/113-285             .............................ne--IGAYITYSVRKLRDNFQ.PATFSTHK.DIAAMSAIILALNAKHPGLNLV.R..A.................NSP.RELVQHLQLK.KA.VLEF-ADcdflf.pfderAIVRM...GT..--L.....HHAIADVRFE.....RD......GSVNLTFVDAG.......HARYDGVKDGL-.-.-.KALNEQL-.....-.E..A....IPDARCTYITS..GAQDSIADCVIFSLCQAIDMH....RN.D-----------fanri.......
A0A068QW43_9GAMM/4-172               .............................nn--LLEYRDEILRKKETHKQ.FDK--FSL.DQGNIRQIINVLNMKYVNMNTE.L..L.................LSQ.LLTPDILNNL.PP.SSHK-R-...........FILQT...NT..GGTg...qHFTATNVFKD.....SE......GRISIIAIDSG.......----IGSNAFI-.-.H.FNIHRNFL.....N.S..N....PEKLKKLYIYS..QIQNSPADCLIFSVHFVKKMY....KH.QTHFVELHHK--lf..........
G6YIH2_9RHIZ/1-161                   .............................ma-----------RYLSANLQ.PDEELLSL.DVDNIDCLADNYNRRYPDLNLR.Y..M.................GSP.AEFLGALADR.SS.DGAWR--...........AVVRL...AD..GEM.....HHFAADVRTR.....AA......AGPTVIVMEPA.......-----DLYTFVT.P.Y.SRLRRETL.....Q.Q..L....GTEQKWAFIGV..GAQKSSSDCLMFGMQFALASY....QK.SSTFDNWHENL-h...........
E9CMN8_9GAMM/46-225                  .......................sveyallh---------TTKLLKENTQ.SNIVSNIF.DTLTLPVICKSESNNIGN-RIV.N..F.................SCL.NSLFTYVNKS.RD.GNFK---...........AITKM...AK..NDSin.rmHYTCIDVFKK.....-G......SKIDLVVYESAc....lqGIASAGPDYGVK.Y.LrNVLKDQFT.....K.GkiK....PENIRVGVIEI..GIQNSPSDCAIFSVSTAKNLY....KN.TET---------selmfskl....
A0A0G3EL98_9BURK/1-39                ...........................mvfs-------------------.--------.----------------------.-..-.................---.----------.--.-------...........-----...--..---.....----------.....--......-----------.......------------.-.-.--------.....-.-..-....-----------..AAQKSPFDCAIFSLSFALKMR....RA.EAFFDELHDSN-d...........
W1IPC6_9GAMM/5-173                   ..............................d-SLNRYIAKIQSNKQNNIQ.--FSDMRM.DMLNCKIILKNLNAKYSDMNAH.P..T................iITA.REFANSINEL.NNlKSNEHKR...........FVINS...DN..GGV.....HFAAANVFKD.....MN......DNISIIFVDSS.......----RGKNQFI-.-.F.F--ILNFR.....L.K..D....VSNIKTLYIYN..QIQNSDADCLLFSLHFLKKMH....KY.SDHFVKLHQD--if..........
Q8Y164_RALSO/86-256                  ..............................p-EFISYAETTLHNLASHTQ.PSVMETNL.DIRHLDTIVQSY--RYNNLNLQ.A..F.................NSR.EAFVASLVEG.QG.SGRAER-...........GVVR-...DY..PNL.....HHFAADVRHH.....ED......GRTTVIILEPA.......---SAGNQENLP.G.Y.TELASALR.....Y.N..L....GSQCRMVVIEA..EAQKSLSDCVAFALDFALAAY....QErRTTFDQWHENL-a...........
A0A1H2PNN8_9BURK/55-227              .............................ta--LDSQLERIERSLEDGSW.AERDFARL.DRHWMPRLVERANQRKDGLDLV.F..L.................QRP.AEFTDELSRI.AR.DEIPASR...........YIVGL...GD..GGM.....HFAVLDVRQS.....-E......RGISVLLFEPA.......TLDADAPGMLA-.-.-.FQTDLAIG.....A.S..A....VPNVRCCKLEL..DLQRSHSECGVFSLFLAKKVH....KA.SDEIEVLHRA--nl..........
A0A014PYK8_9GAMM/69-245              ..............................p-ELLHYAKRVMENAEAGK-.PDAEITHL.DAQNISTLASAYNHAFPALNLK.V..F.................NSG.SDFLSHVYHN.DE.EGAYR--...........AIVKL...SG..NSE.....HRVAVDLRNH.....PD......QTKTMLVIESAt.....aHTYKNGHAETLP.G.Y.IPLRDNID.....K.Y..L....SNSCKMAVIEV..DAQKSHHDCIIFSLNFALAAY....QKdHETFNDLHEKL-r...........
A0A0G3ER55_9BURK/111-216             ........................mvcnnpm-------------------.-----TLR.DRQVLPDLVAAE-RRRTGQDLR.F..Y.................NTL.GEFAQALHAQ.TI.DAGAMRY..........qAVVAMtdrPD..GGA.....HFAAFDMRRR.....ALs...deSPLSMVYVEPS.......------------.-.-.--------.....-.-..-....-----------..---------------------....--.------------flvegqvaega.
Q8XXI2_RALSO/155-342                 ............................pal---PHYLERLEAAYGSDTV.L---HPIE.DIDHMETIIKGLNLADPMLNLH.L..Dkm............qadDSP.EQIRESVLAKtLE.AELR-LEprqra.sngwrEIIH-...--..DTG.....HSIAMGVQCS.....RS.....sNDVSILVIDSGsadrevtKKWRGVVQAIAP.D.I.QAKLGPSV.....S.P..V....RLR--VQFFAI..NTQRSQEGSGIFALSAAKKMA....SD.------------rairglqd....
A0A0M2KAV7_9GAMM/155-327             ..............................g--LYEYAKMAIERVNEKKG.ADKQLSEL.DKKMLPLFAEAENARHPDLNLH.V..F.................RGP.EACYKAIKEQ.NK.KAWDSRQpm.......nmRVVFS...PS..RGIp...dHHVALDVQLR.....PG......HHPSVVCFESA.......---------LWG.M.M.NEIRQDIE.....-.H..G....LKESKVKLIGN..FVQASDWDCAMFALSNALKLY....KHhDEYTSRLHAG--ee..........
A0A328Z5E4_9BURK/71-262              .............................ph--LLAYLRQMERELENQLErPMASDTNS.DMHHLDDIMEALNATTPSLNLC.K..Yafefn......qqleglKKT.GLVTQLFEGM.QT.QGQWH--...........AIFD-...-R..DGK.....HRSAMSVQCA.....-K......DSASLVIVDSL.......PADSITEEVHTG.T.W.TRVLEELQwfldrK.R..NfvepRTQLRAHIVFT..HAQKSDEGCTIFALS-AAKKM....AS.STAIADLHR---qal.........
Q8Y2L4_RALSO/386-577                 .......................vealtdhl-----------DALRRACK.GKADMPAPrDAEFLDLLVEVENKLDPQLRLS.A..Hkida.........prlaVRD.PGAIASLAPV.VA.DGVRGGGd........whATLDI...GD..--G.....HHVAVAARHD.....AAh....pTHVSLAVLDGAg.....sPFSPANWRDLAS.T.V.AKCLDAAG.....N.G..R....TGKVWLTYVDA..SSQATTSNSALFALRATKEMKesglQH.DGLIDQMHKN--al..........
A0A0F5JSW9_9BURK/60-236              ..............................p--LRKYAKAAVERVRHRMA.DAPSFANV.DAAHLDALVATEKQRNPGLNLE.H..F.................SHQ.DDFVEAIRRG.TR.QSFQ---...........AIFPY...PD..PAThqsesHHVMADVRHH.....AD......GTTTVVVVESA.......-EIFAGRGTRLG.K.H.NQIVLALN.....E.V..G....VDSNNIAVIET..QAQKSTDDCVMYSLNYALKAH....KN.QRVFDKFHARL-q...........
Q87GH0_VIBPA/21-193                  ...............................EQLSSYIDLMDDAIRQGKQ.LPKDTAAAnDIALMDDFIAIANQKKEGLNAH.F..F.................RSP.LDMVNYVKSL.IP.SEDTTAR...........FVVNM...GS..GGI.....HCIAVDCAIK.....-N......GKCSLIGIDPV.......TMNSLGASMLA-.-.-.-IRLQSVC.....K.R..E....LPETSLVIMET..DMQRSQGECLMFSLFLVKKMH....KE.CDEFQSLHDKNI............
A0A078L0R4_9GAMM/3-159               ................ddgkikdakfpfnev-------------------.--------.--EIKELIAKQS-FKPHLMIVK.A..N.................AQP.TAFVDYLMNL.SQ.SNKSFRE..........qCIVLY...N-..--E.....HWFGLDLERK.....KR.....tGKISIVILDAA......aPFTKVAAFMFLM.K.Q.ISQNGSIA.....F.D..T....LLIGSN--SDK..NLQRNNRDCSTYAWELLKWA-....KE.------------spnlhdklfk..
A0A370MZA9_9BURK/191-374             asarhfaiarldqvkahfqalllgnwspgpt-------------------.----DDKY.DAAILPAIVAAENDRSPALNLT.L..L.................SPK.EDFASWLKAT.RP.ARAR---...........VMFPM...PG..NDA.....HYVTADIRRI.....-G......GKTSVIVIEPLs....lkDNADLKDSTRDK.Y.E.KRTLPLLK.....K.A..L....KSDVTLSVLTV..DTQKSTNDCRVFALSAAAKLA....DN.AFLIDSLHQQN-l...........
A0A0Q6XHS1_9BURK/11-197              ..............................s-KLQTIRQHFTTLLAGNWS.PGPMDDDF.DHAMLPIMVAAENKRTPNLKLT.V..L.................PTG.TGLVQWLENK.PQ.PEPKWYEkakp...ynerVMFTM...PG..FSA.....HKVVADVMQD.....SK......GNVSVLVVEPLg.....fKENAQIAMRDVA.L.P.TILKAVQN.....S.P..L....GKKISVTVLAL..DTMKSDNDCRIFGLSAASKMA....DQ.PKYFEALHAQNI............
A0A2S0PDD2_9NEIS/267-438             .............................dr--LTSALRLAQRYVQCGRQ.PDTAVTLS.DMVSMREVARCENDRKTGLNLS.L..A.................GSM.DEVAALLAGK.AP.PFHL--R...........LVFRE...PR..HGY.....HHVFADIDAQ.....PG......QPLSAILIETA.......A--AASAHPLYQ.R.F.SQALGQFA.....D.R..H....-DGMLLAVIDS..HVQRSRGDCLIFCMSFALKSH....RH.ASSFTRLHHD--hr..........
A0A366I3T8_9GAMM/1-167               ...............................--MNDYLHKLEHSANNAIQ.PDARTEEM.H--LQKYLIHAQNYKY-DLQIG.L..Ln..............isESRgRELKNALQNM.EN.DTKWH--...........AIVNI...AI..DDEpgdtpHSVAMEAEKK.....-N......GKISLVVVDAN.......------RSPFT-.-.-.--DTDIAI.....H.L..P....GLNAALTVLYT..GTQKTLSGCKIFALNDAKAMA....RN.EDAIARVHQQN-y...........
Q9RI13_YERPE/26-198                  ...............................EELKNIITQLETDISDGSW.FHKNYSRM.DVEVMPALVIQANNKYPEMNLN.L..V.................TSP.LDLSIEIKNV.IE.NGVRSSR...........FIINM...GE..GGI.....HFSVIDYKHI.....-N......GKTSLILFEPA.......NFNSMGPAMLA-.-.-.IRTKTAIE.....R.Y..Q....LPDCHFSMVEM..DIQRSSSECGIFSFALAKKLY....IE.RDSLLKIHEDNI............
A0A0Q6XCB2_9BURK/393-581             ............................qgm---EAYVHELGRAAKGEA-.--PQPTPR.DAEFMGLLIDVENTLDPQLRLS.A..Hrvdp.........vqlaALD.PAAINDLWQS.VA.TGVRSGAd........whATLDL...GG..---.....HHAALSARHD.....PDn....hAHVSLVVVDGTgsp.llrEGGGEGLTKLLGdR.L.QAMLRGTG.....H.A..G....QGKVRLTHFDV..SARQPDIDNALFAVLSAKNL-....KD.FRDIGEAH----aea.........
A0A2G8DX34_9GAMM/26-198              ...............................EEIKKIITQLETDLVNGTW.THKDYGKN.DMKIMPALITQANNKYPEMNAH.Y..I.................LYP.RDLSITIKRT.IE.KRIKSAR...........FIISM...GS..DGI.....HFAVIDYKHI.....-N......NNTSVILFEPA.......KFKGSGASLLA-.-.-.LRARMSIQ.....R.N..P....LPDCHFSVVEM..DIQRSSSECGIFSLALAKKLY....LE.QDSLLKIHEDNI............
A0A1Y6ITH3_9VIBR/59-225              .............................hn--MQEIHQHL-STLRQQNW.SAGSMEAVfDTALLPTMIQAEKAHNPENTVI.F..H.................D--.-DIFDELGEI.DT.EQTRQ--...........-VLMQ...TP..QMF.....HYVAADIREM.....-N......GRRSVIILDSL.......---ADNPRNSIY.D.N.PEVKDSLM.....S.S..L....FPEDKVAVLCM..NMQKSFYECQIFALNATTKMA....KH.ADFMDDLHQ---lnl.........
A0A0G9HUJ3_9XANT/1-61                .............................mn-------------------.--------.----------------------.-..-.................---.----------.--.-------...........-----...--..---.....----------.....--......-----------.......------------.G.Y.QEFISDLN.....D.E..F....GDSASMAIIDV..AAQKSKIGCQQFCLDFTLHAF....HK.SNFFDDLHQRL-h...........
Q8ZMI3_SALTY/40-212                  ...............................EALTCIVERLESEIIDGSW.IHISYEET.DLEMMPFLVAQANKKYPELNLK.F..V.................MSV.HELVSSIKET.RM.EGVESAR...........FLVNM...GS..SGI.....HISVVDFRVM.....-D......GKTSVILFEPA.......ACSAFGPALLA-.-.-.LRTKAALE.....R.E..Q....LPDCYFAMVEL..DIQRSSSECGIFSLALAKKLQ....LE.FMNLVKIHEDNI............
A0A0F5JTZ7_9BURK/1-170               ...............................--MQDFIQALKHAERQGK-.-QYPAAEL.DQKFQPQMVAAQNHIHPKLDVK.V..Fe..............asTSE.PDALRQAIVN.TG.RGERWR-...........AVVNV...ER..IHGklapsHGIALDVSGG.....-R......GKVSVLAIDSV.......--WGCTDTLAV-.-.-.--MT--AA.....L.K..G....VKNAALTILNT..GTQKDVVNCKIFALANAKAMA....DA.GDLMVDLHKKN-f...........
F2JZ26_MARM1/145-319                 ...............................SDLHDYAQHAISCIKTGES.GGYEMNKF.DKKLLPLIAEAENKRTLGLNLH.V..F.................KST.QECTDALHQM.EA.KTNSTRKpn.......hvRIVYP...PA..SGVs..pnHHAALDVKFT.....PK......NPPSIVGFEPA.......----------TF.E.N.SVMLEHSL.....R.Y..S....MPHAKLNVVNP..DIQKSDWDCAMFSLNHALKAH....KHeDGYVEKLHQGE-k...........
A0A1C3TNN7_XANCT/50-221              ..............................a-QLQDYIQALEHAELQGK-.-QYPAAKL.DQKLQPQMVAAQNHIHPKLDVK.V..F.................EAS.RSEPDALRQA.IV.NTRRGERw.........rAVVNV...ER..IDGkgapsHGIAVDVSGG.....-R......GKVSVLAVDSV.......--WGCTDTLAV-.-.-.--MT--AA.....L.K..G....VKNAELTILNT..GTQKDNVNCKIFALANAKAMA....DA.DDLMVDLHKKN-f...........
A1TQP0_ACIAC/91-261                  ...............................SSIVKYGERTLKMLAANKQ.PDEALLKL.DIKNLPALASVYNRRYPGLNIQ.H..F.................DSP.IDFLQSLSEQ.TT.SVVSQR-...........AVLRL...ER..DGE.....HHVAADVRRR.....PN......GEASVIVLEPA.......-----RLLTFVT.G.H.TQLRRQAL.....S.Q..L....GENAKFAFIQV..GAQKSAADCLMFDLHFALHAH....QH.SSLFDQWHDNM-v...........
A0A0G4JVB0_9GAMM/75-250              ..............................p-ELAHYARKTLEQASSGQ-.TTVEITNL.DIGNIRTLVNTYNDRFSSLNLK.Y..F.................SSQ.EDFLDELRDT.DT.SAWR---...........AILKA...AP..NSR.....HHFAIDIRTH.....DD......GQKTLIALEPSva...frPIDDERFHS-MP.G.Y.YSLHRGIQ.....R.Q..S....DDDVKFAVIQT..EAQKSTQDCVIFSLNFALNAY....QK.DSFFDDLHDNL-k...........
A1TST1_ACIAC/147-332                 ..........................celra-----LAAEVHAEGASPDD.EPAAFRKL.DKLAMPAIVSALNAEDPRLRLVyA..H.................ASV.PDDRGVVPDH.RG.FGSVEWRsfladaapgrwRIVL-...-D..NAA.....HNLALDLHVEglpgePG......RRGSVVHMNSS.......VAEGAEPIITA-.-.-.AEMAAHLR.....L.P..E....G--WPLLLLDV..PAQKSLRSCRIFALSMALKCA....-A.DASLEELHAR--ql..........
A0A0Q6VWW2_9BURK/57-238              .............................qk--ISAYVDELRTHLKNHT-.---EPEPR.DHLFLDVLASSENIRTPGLNLR.I..L.................RSA.KSALHAVARA.LA.DAPPPGAapga...lqwqAVFD-...--..DGG.....HRVAASVRID.....RDd....pGRASVILIDSRl....kgAKDHHGHAENIH.DpA.LPTLSQTL.....D.S..K....GLKLQVTYMST..DAQR-NLGCTIFALS-AVKKM....HD.SAAIDQMHSD--al..........
A0A078KYG8_9GAMM/7-168               ................nkllaqlsklkkghd-------------------.-----AGL.DAEGIKVILHNHNRVNPNKNPI.T..L.................VQN.DNFAEVINET.LK.NHDKSKPgr.......yqFIVK-...--..SGA.....HYTTVDLEID.....EQ......GHAKALVLDAA.......--NDMRFIPLLT.K.-.LSSIEGIE.....R.V..Y....YAEGKTN--RD..NIQKDNISCPVFALSHAMALQ....S-.------------ldiynhleqee.
A0A0Q8PB81_9BURK/18-198              ............arsvqdltsaltegrayhd---------------VNMQ.PDERIYQN.DRKNIALMINYLDANIPGLLLH.AksF.................DTP.TAFAVYLRDS.LD.EPRHER-...........ALIRM...GE..NEA.....HYTVVDYMIK.....VKcsgpesNQVSVMAFDPS.......---STPTAAVA-.L.G.VGRLGNAL.....H.A..A....VPQVVASYTLS..NAQTSPKDCIVFALLYATKLC....LR.REIFK-------srqa........
A1TP56_ACIAC/85-258                  ...............................SDLRAYAEAALTAAKIGS-.-TSDMTDL.DVQNKQYLADAYNTRFPDLKLI.C..H.................DSA.QAFFSDFMTS.EK.PVWR---...........SLVQL...SP..HSL.....HHVAIDVRLQ.....-D......GKRTAVVLEPAi....gyGMRSDGKITMLA.G.Y.EPLGRNIQ.....K.Y..L....GENGDMAVVQL..GAQKSHYDCIIFSLNLALCAY....QR.DDVIDGLHERL-r...........
B2VJH3_ERWT9/142-315                 ..............................n-NLHEYGKMATELAKEGSG.SSSALTRM.DKKVLPLLADAENARHPGLNLH.V..Y.................KKG.EECYQAIKDQ.HK.SVQQSGQpk.......tmRALYP...PF..KGMp...dHHIALDIQLR.....PG......HRPSIVGFESA.......----------LG.H.M.VEHLKQGI.....A.E..G....VRGAKVHMVGN..TIQNSQWDCTMYSLSNALKSF....KHhDEYTARLHKGE-k...........
A0A1H2PNL8_9BURK/49-221              ...........................sfla----AKIEEIERSLNDGSW.TEMDFAEV.DEALMPGLVAMANDKKTGLDLC.Y..L.................PAP.KDLCDSLDAF.WR.DGLESKR...........YVVNS...GN..SAT.....HFVALDVAVV.....-D......GKVSVALFEPT.......TFDHTTPCLLA-.-.-.ALIKVAVK.....R.T..A....LPHAKVVSVAL..DIQRSNAECGMFSLALAKKLL....KE.RDQILALHKAN-l...........
A0A3S4G8F4_SALBN/25-197              ...............................ETLTCIIERLENDIIDGSW.MNASYEET.DLRVMPLLVAQANKKYPALNLE.F..V.................MST.PELVSAIKEA.RM.GGSESAR...........FIVNL...GS..GGI.....HFSVVDFRAV.....-A......GKTSVILFEPA.......ECDAFGPALLA-.-.-.LSTKAAIE.....R.E..Q....MSDCYFAMVEL..DIQRSASECGIFSLALAKKCY....LE.SANLARIHEDNI............
A0A0G4JW18_9GAMM/87-255              ..............................k-QLNNYLNKLESHASDSIQ.PNVRTEES.--ALQKYLIMAQNDKHH-LQIG.L..Lsi.............saTNG.DELKNALRMM.DN.NTKW--R...........AVMNI...AD..DDEpneppHSVAVEAEKK.....-N......NKISLVVVDAY.......------ASAFT-.-.D.SDIAEHIT.....D.-..-....-HDAALTVLFT..SVQKSPSGCKIFSLHDVKAMA....SR.EEVMNQFHQRN-y...........
A0A0Q6XCB2_9BURK/94-286              .............................qe--MKGYLAELRLMHAAGR-.---ELPRSrDTQFLDLLVVMENARNASLRLS.A..Qaidhe......aldkgdAAA.MKAVAGLARA.AI.EGMGQGSw.........hAVLSV...DG..---.....HEVAVAAEHD.....EKh....pARLSLIVVDSAssl.lssGQWRQIARLVGQ.H.M.NRALADEG.....K.P..T....DAQVWVSCLSTstEVTATCGGSTIFSLA-AAREM....PH.DPDIQKLHKD--vl..........
Q8P4H6_XANCP/1-140                   ...............................-------------------.--------.-------MVAAQNHIHPNLDVK.V..F.................DAS.ASEPHALRQA.IV.NTGRGQRw.........rAVVNV...ER..IHGkgapsHGIAVDVSGG.....-R......GKVSVLAVDSV.......--WGCADTLSV-.-.-.--MT--AA.....L.K..G....VKNATLTILNT..GTQKDVINCKTFALANAKAMA....DN.DDLMVDLHKKN-f...........
Q8Y125_RALSO/174-347                 ................qalsaqnmdpelaqf-------------------.---RVLDV.DRAIMPLLIVAENARNPGLNLV.P..Lhmdmaed..eevrtqppMAG.SRHIAEFVAS.AR.PGRY--R...........AVID-...--..DGS.....HTRAADIRKD.....-A......SGTSVIVVDPL.......---RKEKDESA-.-.Y.VDYADNVN.....M.E..F....GEHAKCAFIPV..DIQKSFFDCRILSLSLALKMH....DK.DDAFAAFHETL-r...........
W3U0J6_BARQI/51-223                  ...............................EKLKGIITDLESDLASGKW.INAFYANI.DLKMMPALVKQANTKYPEMNLK.L..A.................LTP.QELVFSIKET.IN.SGVQSSR...........FIVNL...GG..SRI.....HFAVIDHQTV.....-A......DKTSLLLLEPT.......SFENGSAAMMG-.-.-.LRTKKALQ.....D.S..D....LSHYSFSMAEM..NIQRSTSECGIFSLALAKKLY....LE.SDKLKKMHTDN-v...........
Y4LO_SINFN/42-211                    ...............................SSLMEYGRQVARHLSANVQ.PDEKILSL.DIRNLPLLAASYNRRYPDLDLR.H..M.................DSP.ARFFDALNDR.SS.DGAWR--...........AVVRL...AD..GEQ.....HHVAADVRTR.....AG......AAPTIIVMEGA.......-----NFYTFVA.S.Y.FKLRGDSF.....R.Q..L....GTQAKWAFIEV..GAQKSAADCVMFGVQFALAAY....RE.LPTFDAWHDNL-h...........
A0A328ZTJ4_9BURK/55-231              ........................aaldtem-------RKVRVDIHARRQ.PDADTLKA.DLSNIRSIVQAQNLRKPGLELS.Y..H.................GSS.ESLVDAMRNL.DT.SQNHQFR...........AIFRI...DNrpQGM.....HHAVVDVRVK.....PD......MPPTVIAMETA.......---TMGAGDNID.S.Y.SEFVDQLR.....SvP..G....MQEARVVVIDA..EAQKSDADCVMFGLSFASRMH....KD.AGLLEGWHEKL-a...........
Q1MTJ6_RALSO/1-95                    .............................rl-------------------.--------.----------------------.-..-.................---.----------.--.-------...........-----...RA..DHD.....HVVSADVRTV.....-G......PAVSILILEPV.......--DQFSVRRLL-.-.-.ESCLEEMA.....G.L..L....PSNAAVSVLIH..DSQKSKFDCAIFALHAASKMV....DE.RRFLDALHAE--ha..........
#=GC seq_cons                        .................................h.thhpth.pthtts....t.thtph.DhthhshlltstNt+hPsLsLp.h..h.................tss.tphhptlppt.tt.sshpt.............tllph...st..ssh.....HasAhDlctc......s......spsSllll-su..........t.s.thhh.......phhttht.....p.t..t....h.psphshlps..shQ+Sst-CtlFuLshAh+hh....pc.pphhsphHpp..h...........
//
DBGET integrated database retrieval system