GenomeNet

Database: Pfam
Entry: Adeno_E3_CR2
LinkDB: Adeno_E3_CR2
Original site: Adeno_E3_CR2 
#=GF ID   Adeno_E3_CR2
#=GF AC   PF02439.15
#=GF DE   Adenovirus E3 region protein CR2
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_1854 (release 5.4)
#=GF GA   26.20 26.20;
#=GF TC   26.40 26.60;
#=GF NC   26.10 26.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   8627757
#=GF RT   Early region 3 of adenovirus type 19 (subgroup D) encodes an
#=GF RT   HLA-binding protein distinct from that of subgroups B and C. 
#=GF RA   Deryckere F, Burgert HG; 
#=GF RL   J Virol 1996;70:2832-2841.
#=GF DR   INTERPRO; IPR003470;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Early region 3 (E3) of human adenoviruses (Ads) codes for
#=GF CC   proteins that appear to control viral interactions with the host
#=GF CC   [1]. This region called CR2 (conserved region 1) [1] is found in
#=GF CC   Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3
#=GF CC   region. CR2 is also found in the 20.1 Kd protein of subgroup B
#=GF CC   adenoviruses. The function of this 50 amino acid region is
#=GF CC   unknown.
#=GF SQ   34
#=GS A0A135LAA2_PENPA/104-141  AC A0A135LAA2.1
#=GS A0A0K0PY77_9ADEN/197-232  AC A0A0K0PY77.1
#=GS W5K4C1_ASTMX/244-276      AC W5K4C1.1
#=GS Q91CK4_ADE16/135-171      AC Q91CK4.1
#=GS Q9PX68_ADE07/135-171      AC Q9PX68.1
#=GS Q76Y39_ADE35/143-179      AC Q76Y39.1
#=GS F4PKM2_CAVFA/4-39         AC F4PKM2.1
#=GS H2U5U0_TAKRU/240-273      AC H2U5U0.1
#=GS C7SRR3_9ADEN/136-173      AC C7SRR3.1
#=GS Q3ZKT4_9ADEN/135-171      AC Q3ZKT4.1
#=GS Q8UY72_9ADEN/158-196      AC Q8UY72.1
#=GS D2DMA7_ADE1A/139-175      AC D2DMA7.1
#=GS M1BIA2_SOLTU/225-262      AC M1BIA2.1
#=GS Q76Y40_ADE35/136-173      AC Q76Y40.1
#=GS Q3ZKT3_9ADEN/145-181      AC Q3ZKT3.1
#=GS Q6QPD0_9ADEN/158-195      AC Q6QPD0.1
#=GS W6Q867_PENRF/118-155      AC W6Q867.1
#=GS A0A0K0PY81_9ADEN/144-182  AC A0A0K0PY81.1
#=GS Q4KSJ0_9ADEN/376-414      AC Q4KSJ0.1
#=GS M1BIA1_SOLTU/225-262      AC M1BIA1.1
#=GS Q91CK3_ADE16/145-181      AC Q91CK3.1
#=GS Q9PX39_ADE07/145-181      AC Q9PX39.1
#=GS A0A1S3MZ11_SALSA/242-277  AC A0A1S3MZ11.1
#=GS M5FRW7_DACPD/470-506      AC M5FRW7.1
#=GS V7BZJ4_PHAVU/446-483      AC V7BZJ4.1
#=GS C4P226_9ADEN/375-413      AC C4P226.1
#=GS Q77N38_9ADEN/381-419      AC Q77N38.1
#=GS V4A5G2_LOTGI/196-230      AC V4A5G2.1
#=GS C3UZL5_9ADEN/136-173      AC C3UZL5.1
#=GS A0A178EJV4_9PLEO/490-526  AC A0A178EJV4.1
#=GS K9FNB3_PEND2/143-180      AC K9FNB3.1
#=GS B9A5S3_9ADEN/367-405      AC B9A5S3.1
#=GS A0A2C9M757_BIOGL/182-219  AC A0A2C9M757.1
#=GS Q6QPD1_9ADEN/181-219      AC Q6QPD1.1
A0A135LAA2_PENPA/104-141             .ssnlg------AIIGGV.VGGVAVLVICaILL.FFCCRRKRR-YgK-r...
A0A0K0PY77_9ADEN/197-232             ......IPNSISGIIALL.TVGI-VIILC.IMI.YAYCYKKIH-H.KQ....
W5K4C1_ASTMX/244-276                 .....g---STAGIIGGV.IAGIAVLVL-.-II.YCCCRKKEKP-.--ee..
Q91CK4_ADE16/135-171                 ......IPNSMIAIIAAV.ALGMALIIIC.MFL.YACCYKKFK-H.KQ....
Q9PX68_ADE07/135-171                 ......IPNSMIAIIAAV.ALGMALIIIC.MFL.YACCYKKFQ-H.KQ....
Q76Y39_ADE35/143-179                 ......ISTSTISIIAAV.TIGISILVFT.ITY.YACCYRKDK-H.K-g...
F4PKM2_CAVFA/4-39                    .....s--EAVIAIIVSI.VVVFALISLA.VFI.YIFVYKKRQR-.--es..
H2U5U0_TAKRU/240-273                 .....a---STVGIIGGV.LAGIVVLAII.ICC.--CCRRRGKNQ.K-d...
C7SRR3_9ADEN/136-173                 ......IPDSMIAIIAAV.AVVMALPVIC.MLL.YACRYKKFHPK.KQ....
Q3ZKT4_9ADEN/135-171                 ......IPNSMIAIIAAV.ALGMALIIIC.MFL.YACCYKKFQ-H.KQ....
Q8UY72_9ADEN/158-196                 ......IPKSMIGIIVAV.VVCMLIIALC.MVY.YAFCYRKHRLNdK-l...
D2DMA7_ADE1A/139-175                 ......ISTSTISIIAVV.TIGISILVFT.ITY.YTCCYKKDE-H.K-g...
M1BIA2_SOLTU/225-262                 ......-SSSTVAIVAAVsVTGLLILAVV.IVC.LLCNRKKKK--.--qpyy
Q76Y40_ADE35/136-173                 ......IPDSMIAIVAAV.AVVMALIIIC.MLL.YACRYKKFHPK.KQ....
Q3ZKT3_9ADEN/145-181                 ......IPKSTIGIITAV.VVGLMIIFLC.IMY.YACCYRKHE-Q.K-g...
Q6QPD0_9ADEN/158-195                 ......CPGPLVSGIVGV.LSGLAVIIIC.MFI.FACCYRRLYRQ.KS....
W6Q867_PENRF/118-155                 .ssnlg------AIIGGV.VGGVAVLVICaILL.FCCCRRKRK-HgK-r...
A0A0K0PY81_9ADEN/144-182             ......IPKSTIGIIVAV.AIGMIIIIIC.MIV.YACCYRKFQHEeK-g...
Q4KSJ0_9ADEN/376-414                 ......IPSTTVAIVVGV.IAGFITIIIV.ILC.YICCRKRPRAYnHM....
M1BIA1_SOLTU/225-262                 ......-SSSTVAIVAAVsVTGLLILAVV.IVC.LLCNRKKKK--.--qpyy
Q91CK3_ADE16/145-181                 ......IPKSTIGIITAV.VVGLIIIFLC.IMY.YACCYRKHE-Q.K-g...
Q9PX39_ADE07/145-181                 ......IPKSTIGIITAV.VVGLIIIFLC.IMY.YACCYRKHE-Q.K-g...
A0A1S3MZ11_SALSA/242-277             .....m--GSTAGIIGGV.AVGVLVLLII.LLY.CCCCRKKKD--.--kae.
M5FRW7_DACPD/470-506                 .....q---SHLAIVIGV.SVGVVVLILL.IIA.FCCCRRRRPVQ.--qyq.
V7BZJ4_PHAVU/446-483                 .....a--TTIIGIVAGV.VSGVVLISLI.FFL.VVCFRRKRTTQpK-d...
C4P226_9ADEN/375-413                 ......IPSATVAIVVGV.IAGFITIIIV.ILC.YICCRKRPRAYnHM....
Q77N38_9ADEN/381-419                 ......IPSTTVAIVVGV.IAGFITLIIV.FIC.YICCRKRPRAYnHM....
V4A5G2_LOTGI/196-230                 .....t--SSLIGIIVAV.I--FIVVVIV.VIV.YICRRKRQKR-.--grs.
C3UZL5_9ADEN/136-173                 ......IPDSMIAIIAAV.AVVMALTVIC.MLL.YACRYKKFHPK.KQ....
A0A178EJV4_9PLEO/490-526             sssmrt------AIIAGV.TVTVVILIIC.IIW.LAYLYRKRR--.--nfr.
K9FNB3_PEND2/143-180                 .ssnlg------AIIGGV.VGGIAVLILC.IVLlFCCCRRKRE-YgK-r...
B9A5S3_9ADEN/367-405                 ......IPSATVAIVVGV.IAGFVTLIIV.FIC.YICCRKRPRSYnHM....
A0A2C9M757_BIOGL/182-219             .....l-SDSTIGIIVGV.VLGSATIVSI.VVV.LAWRRKKQKS-.--ikk.
Q6QPD1_9ADEN/181-219                 ......IPKSMIGIIVAV.VVCMLIIALC.MVY.YAFCYRKHRLNdK-l...
#=GC seq_cons                        .......spShluIIsuV.lsGhhlllls.hlh.YsCCh+Kt+...K.....
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