GenomeNet

Database: Pfam
Entry: Bacillus_HBL
LinkDB: Bacillus_HBL
Original site: Bacillus_HBL 
#=GF ID   Bacillus_HBL
#=GF AC   PF05791.12
#=GF DE   Bacillus haemolytic enterotoxin (HBL)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_7539 (release 8.0)
#=GF GA   27.30 27.30;
#=GF TC   27.40 27.30;
#=GF NC   27.20 27.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Bacillus_haemolytic_enterotoxin
#=GF RN   [1]
#=GF RM   12039781
#=GF RT   Enterotoxin production in natural isolates of Bacillaceae
#=GF RT   outside the Bacillus cereus group. 
#=GF RA   Phelps RJ, McKillip JL; 
#=GF RL   Appl Environ Microbiol 2002;68:3147-3151.
#=GF DR   INTERPRO; IPR008414;
#=GF DR   TC; 1.C.41;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several Bacillus haemolytic enterotoxins
#=GF CC   (HblC, HblD, HblA, NheA, and NheB) which can cause food
#=GF CC   poisoning in humans [1].
#=GF SQ   110
#=GS D8QBX8_SCHCM/45-214       AC D8QBX8.1
#=GS A0KLE1_AERHH/3-177        AC A0KLE1.1
#=GS A0KLE1_AERHH/3-177        DR PDB; 6H2F I; 3-177;
#=GS A0KLE1_AERHH/3-177        DR PDB; 6H2F F; 17-177;
#=GS A0KLE1_AERHH/3-177        DR PDB; 6H2F C; 3-177;
#=GS A0KLE1_AERHH/3-177        DR PDB; 6H2F J; 17-177;
#=GS A0KLE1_AERHH/3-177        DR PDB; 6H2F E; 3-177;
#=GS A0KLE1_AERHH/3-177        DR PDB; 6H2F A; 3-177;
#=GS A0KLE1_AERHH/3-177        DR PDB; 6H2F D; 17-177;
#=GS A0KLE1_AERHH/3-177        DR PDB; 6H2F H; 17-177;
#=GS A0KLE1_AERHH/3-177        DR PDB; 6H2F G; 3-177;
#=GS A0KLE1_AERHH/3-177        DR PDB; 6H2F B; 17-177;
#=GS A7GNS5_BACCN/53-231       AC A7GNS5.1
#=GS A0A0F7RDK7_BACAN/41-216   AC A0A0F7RDK7.1
#=GS A0A023BU94_9FLAO/7-179    AC A0A023BU94.1
#=GS I8AH38_9BACI/51-228       AC I8AH38.1
#=GS C3BJ58_9BACI/42-216       AC C3BJ58.1
#=GS A0A238VCQ8_9FLAO/34-182   AC A0A238VCQ8.1
#=GS Q81BP7_BACCR/35-207       AC Q81BP7.1
#=GS Q81EZ7_BACCR/54-232       AC Q81EZ7.1
#=GS F1A3V0_DICPU/4-148        AC F1A3V0.1
#=GS A0A140NJL1_PROSM/4-178    AC A0A140NJL1.1
#=GS A0A1S9AXE6_9BACT/62-213   AC A0A1S9AXE6.1
#=GS A0A073JQZ5_9BACI/44-222   AC A0A073JQZ5.1
#=GS A5N119_CLOK5/38-211       AC A5N119.1
#=GS I8UCU6_9BACI/42-216       AC I8UCU6.1
#=GS A0A1C5FAJ5_9ACTN/10-185   AC A0A1C5FAJ5.1
#=GS C3BJ59_9BACI/55-233       AC C3BJ59.1
#=GS A0A073JTG8_9BACI/42-216   AC A0A073JTG8.1
#=GS Q81BP9_BACCR/45-224       AC Q81BP9.1
#=GS A0A326U203_9CHLR/46-202   AC A0A326U203.1
#=GS A0A3Q9G360_STRLT/9-185    AC A0A3Q9G360.1
#=GS A0A1V2SKP7_9BACI/26-204   AC A0A1V2SKP7.1
#=GS C3BUX8_9BACI/4-183        AC C3BUX8.1
#=GS A0A077LMV2_9PSED/34-191   AC A0A077LMV2.1
#=GS A0A1H7IRI4_9PROT/48-193   AC A0A1H7IRI4.1
#=GS D8Q4J7_SCHCM/47-215       AC D8Q4J7.1
#=GS A0A0T9L222_9GAMM/5-178    AC A0A0T9L222.1
#=GS A0A069PJF8_9BURK/13-186   AC A0A069PJF8.1
#=GS A0A1G6J653_9BACI/46-223   AC A0A1G6J653.1
#=GS A0A1U9JJ99_9NEIS/42-196   AC A0A1U9JJ99.1
#=GS A0A1B6AEI3_9ACTN/8-166    AC A0A1B6AEI3.1
#=GS G7ZI37_AZOL4/95-285       AC G7ZI37.1
#=GS A0A0W7YA76_9BACI/47-233   AC A0A0W7YA76.1
#=GS A0A2B4SMG0_STYPI/704-875  AC A0A2B4SMG0.1
#=GS A0A1V2SK11_9BACI/46-224   AC A0A1V2SK11.1
#=GS A0A2B4SHY1_STYPI/6-139    AC A0A2B4SHY1.1
#=GS A0A182VI53_ANOME/15-146   AC A0A182VI53.1
#=GS A0A2N1A316_9GAMM/58-248   AC A0A2N1A316.1
#=GS D8Q0V9_SCHCM/44-212       AC D8Q0V9.1
#=GS G8MGH7_9BURK/12-186       AC G8MGH7.1
#=GS A0A0D8CW88_9GAMM/67-249   AC A0A0D8CW88.1
#=GS A0A1C7MIT9_GRIFR/59-222   AC A0A1C7MIT9.1
#=GS D8Q5Q7_SCHCM/48-214       AC D8Q5Q7.1
#=GS A0A1I3AW30_9PROT/52-196   AC A0A1I3AW30.1
#=GS A0A0F7G0M4_9ACTN/6-187    AC A0A0F7G0M4.1
#=GS W4LPM0_9BACT/9-201        AC W4LPM0.1
#=GS A0A014MG07_9GAMM/4-177    AC A0A014MG07.1
#=GS D8QBU9_SCHCM/72-235       AC D8QBU9.1
#=GS R4L9T5_9ACTN/6-182        AC R4L9T5.1
#=GS Q81EZ8_BACCR/41-216       AC Q81EZ8.1
#=GS A0A1G6J8N4_9BACI/41-227   AC A0A1G6J8N4.1
#=GS A0A3G3GSJ1_9BACT/13-182   AC A0A3G3GSJ1.1
#=GS D8Q589_SCHCM/40-211       AC D8Q589.1
#=GS R4LLT0_9ACTN/12-183       AC R4LLT0.1
#=GS A0A1V6P0T9_PENDC/65-235   AC A0A1V6P0T9.1
#=GS C3BJ60_9BACI/69-247       AC C3BJ60.1
#=GS F4KUV6_HALH1/16-197       AC F4KUV6.1
#=GS D8QB82_SCHCM/52-215       AC D8QB82.1
#=GS A0A1H8U6W1_9SPHI/73-201   AC A0A1H8U6W1.1
#=GS A0A1M7IPT0_9BACT/13-190   AC A0A1M7IPT0.1
#=GS A0A1V2SKA8_9BACI/31-205   AC A0A1V2SKA8.1
#=GS A8PME4_9COXI/58-232       AC A8PME4.1
#=GS A0A1B6AEA3_9ACTN/18-186   AC A0A1B6AEA3.1
#=GS A7GNS4_BACCN/41-216       AC A7GNS4.1
#=GS C3BVE6_9BACI/1-174        AC C3BVE6.1
#=GS Q813Q6_BACCR/46-224       AC Q813Q6.1
#=GS A0A238VAM4_9FLAO/16-188   AC A0A238VAM4.1
#=GS A0A0W7YA82_9BACI/35-207   AC A0A0W7YA82.1
#=GS Q9KL64_VIBCH/12-189       AC Q9KL64.1
#=GS Q9KL64_VIBCH/12-189       DR PDB; 6DFP A; 12-189;
#=GS Q9KL64_VIBCH/12-189       DR PDB; 6EZV X; 12-189;
#=GS A0A3G3GSG2_9BACT/6-184    AC A0A3G3GSG2.1
#=GS A7GNS6_BACCN/40-218       AC A7GNS6.1
#=GS A8PKF9_9COXI/30-206       AC A8PKF9.1
#=GS F4KUV7_HALH1/16-197       AC F4KUV7.1
#=GS D8QG72_SCHCM/49-221       AC D8QG72.1
#=GS A7UVL7_ANOGA/1-117        AC A7UVL7.1
#=GS A0A1C7MQ73_GRIFR/152-315  AC A0A1C7MQ73.1
#=GS Q7BYC6_BACCR/44-230       AC Q7BYC6.1
#=GS A0A0F7RFS4_BACAN/54-232   AC A0A0F7RFS4.1
#=GS A0A1H0Q479_9ACTN/12-186   AC A0A1H0Q479.1
#=GS F4KUV5_HALH1/5-154        AC F4KUV5.1
#=GS A8PKF7_9COXI/22-202       AC A8PKF7.1
#=GS I8AGD4_9BACI/45-223       AC I8AGD4.1
#=GS D0LUR3_HALO1/94-266       AC D0LUR3.1
#=GS A0A073JT53_9BACI/55-232   AC A0A073JT53.1
#=GS D8QBX6_SCHCM/48-214       AC D8QBX6.1
#=GS Q7BYC7_BACCR/45-224       AC Q7BYC7.1
#=GS A0A3G3GSP0_9BACT/8-192    AC A0A3G3GSP0.1
#=GS A0A077LYS1_9MICO/10-184   AC A0A077LYS1.1
#=GS A0A0N8W5T9_9SPHI/30-213   AC A0A0N8W5T9.1
#=GS A0A023BTX0_9FLAO/6-175    AC A0A023BTX0.1
#=GS A0A3N7AAG7_9BACT/48-206   AC A0A3N7AAG7.1
#=GS A0A2S1LRP1_9FLAO/68-213   AC A0A2S1LRP1.1
#=GS A0A1B6AEW6_9ACTN/14-187   AC A0A1B6AEW6.1
#=GS A0A1I4QEG0_9PSED/13-184   AC A0A1I4QEG0.1
#=GS A0A1C7MI70_GRIFR/79-249   AC A0A1C7MI70.1
#=GS A0A3A9EJH8_9FIRM/1-77     AC A0A3A9EJH8.1
#=GS L8JDA2_9GAMM/90-243       AC L8JDA2.1
#=GS A0A182K4B2_9DIPT/1-116    AC A0A182K4B2.1
#=GS A0A1L9RIA1_ASPWE/50-217   AC A0A1L9RIA1.1
#=GS Q6LH90_PHOPR/5-179        AC Q6LH90.1
#=GS A0A182LQZ9_9DIPT/1-117    AC A0A182LQZ9.1
#=GS A0A1Y2M621_EPING/89-240   AC A0A1Y2M621.1
#=GS A0A233HNS4_9VIBR/12-189   AC A0A233HNS4.1
#=GS A0A2B4SLM4_STYPI/8-182    AC A0A2B4SLM4.1
#=GS A0A0W7YA75_9BACI/47-226   AC A0A0W7YA75.1
#=GS A0A0D3V886_9BACL/48-207   AC A0A0D3V886.1
#=GS A0A1G6J6S1_9BACI/49-199   AC A0A1G6J6S1.1
#=GS A0A094E4U9_9PEZI/53-218   AC A0A094E4U9.1
#=GS A0A094G668_9PEZI/53-218   AC A0A094G668.1
D8QBX8_SCHCM/45-214                  ......................................tdtl----------------------------QQRLNVSTATM.......rKLSEVV...TPLLAT..FNDVKAHCETF........KDKTYPSI....VSIA.DDIYSY.....AqdaggT.....E.....QNSYYANILRCIrsl........atasSKPEKD.DLKQTIDSLcdglI...K....N....ATAI............QTKIQEVVENVSKFGDQTYEDS.....SALKERK.......LA..VEDMLTSDA....GSLEALQRQLEENHTELK--ad.....................
A0KLE1_AERHH/3-177                   .....................................natti-----TMDQGMANQASQAMQIQTYCNSVKQQVPVDFSQF.......pNLKDNQ...TQINQG..LDLAKGHADLY........LNTIQPQI....ITNI.SNISNY.....F.....A.....L.....QNAIPAVLPPGS...............---TKA.QWLRQLSVI....K...E....Q....ATEY............QRLSSDTRLVIVNLNNNLITDS.....SNFQGIV.......VN..LNSKVQGNN....GVLAQLNGDIDKVNAAID--ga.....................
#=GR A0KLE1_AERHH/3-177        SS    .....................................HHHHH-----HHHHHHHHHHHHHHHHHHHHHHHHT------TT-.......GGGHHHH...HHHHHH..HHHHHHHHHHH........HHTHHHHH....HHHH.HHHHHH.....H.....H.....H.....CHCHHHCS-TT-...............----HH.HHHHHHHHH....H...H....H....HHHH............HHHHHHHHHHHHHHHHHHHHHH.....HHHHHHH.......HH..HHHHHCCCC....CHHHHHHHHHHHHHHHHH--HH.....................
A7GNS5_BACCN/53-231                  ..........................................SLGPEGLKDAMERTGSNALVMDLYALTIIKQGNVSFGNVt......tVDAPLR...AKIVQH..QNTARSNAKQW........LDVLKPQL....ISTN.QNIINY.....N.....T.....K.....FQNYYDTLVKAV...............DTKDKA.TLTKGLTRL....S...N....S....ITEN............KEQVDKLVEDLKRFRNKMTADT.....QNFKTDA.......NQ..ITSILASQD....AGIPLLQSQITTYNEAMSK-y......................
A0A0F7RDK7_BACAN/41-216              .........................................v-IAPNTLSNSIRMLGSQSPLIQAYGLVILQQPDIKVNAM........------...SSLTNH..QKFAKANVREW........IDEYNPKL....IDLN.QEMMRY.....S.....T.....R.....FNSYYSKLYELAgn..........vneDEQAKA.DFTNAYGKL....Q...L....Q....VQSI............QESMEQDLLELNRFKTVLDKDS.....SNLSIKA.......DE..AIKTLQGSS....GDIVKLREDIKRIQGEIQA-e......................
A0A023BU94_9FLAO/7-179               ......................................yikn------IEVSQKETTTNGLVLQSYCNSILQQPNLDFSSS.......eDLVGIQ...NSINDS..IENAKESANSY........LSDINPKI....ISSL.SDLKSY.....F.....T.....V.....YRVVPVTLPEGA...............---TVD.QWLSVLTVI....K...G....L....TENN............LRNSEIIVQGLSDLSIRLKADA.....NAFNELA.......QK..ANEMISGDQ....GELADISDELKSIDRSINA-q......................
I8AH38_9BACI/51-228                  .........................................q-LGPDGLREALAETGNHTIVMDLYALSVLKQANITLNGVt......sIDDTLK...GKINSH..QSLSKANANFW........LDTVKPHI....VQTN.QNIVNY.....D.....T.....K.....FSTYYNTLIKAV...............DDGNKK.TLETGLTKL....K...T....E....ISGN............QEEVENLIQELQSFRNKLSKDT.....QSFKDDA.......NE..VTAILASED....AGIPLLENQITTYNKTV---rd.....................
C3BJ58_9BACI/42-216                  ........................................ta---RNTLSNSIRTLGANTPLIQAYGLVILQQPDIKVSAM........------...SSLTDF..QKIAKTNVREW........VDEYNPKL....MDLN.QEMMRY.....S.....T.....R.....FNSYYSKLYDLAgk..........vneDEQAKN.DFVSAFGRL....H...S....Q....SQTI............QDDMEQTLLELNRFKALLDKDN.....ASLSQKA.......DT..AIQSLKGSN....GDIVQIRADIKRIQEEIQA-e......................
A0A238VCQ8_9FLAO/34-182              ........................ligtlpeepnwipavrse---------------------------------------........------...------..MKLLSKAGSNW........ILNYPNSW....ADIL.TSFANY.....G.....T.....D.....FAAFSEEIKKNI...............HNLSKN.QIISLLSAL....S...D....E....LGNC............ASNTKKSLDALIGFENQFTSVF.....PALNASI.......NS..GWEELSEEE....AEMVAIAEALTHLQDEIA--slqskid................
Q81BP7_BACCR/35-207                  .........................................q-QEGMDISSSLRKLGAQSKLIQTYIDQSLMSPNVQLEEV........------...TALNTN..QFLIKQDMKEW........SSELYPQL....ILLN.SKSKGF.....V.....T.....K.....FNSYYPTLKSFV..............dNKEDRE.GFSDRLEVL....Q...E....M....AMTN............QENTQRQINELTDLKLQLDKKL.....KDFDTNV.......AT..AQGILSTDG...tGKIDQLKNEILNTKKAIQN-d......................
Q81EZ7_BACCR/54-232                  ..........................................SLGPEGLKDAMERTGSNALVMDLYALTIIKQGNVNFGNVs......sVDAALK...GKVIQH..QDTARGNAKQW........LDVLKPQL....ISTN.QNIINY.....N.....T.....K.....FQNYYDTLVAAV...............DAKDKA.TLTKGLTRL....S...S....S....INEN............KAQVDQLVEDLKKFRNKMTSDT.....QNFKGDA.......NQ..ITSILASQD....AGIPLLQNQITTYNEAISK-y......................
F1A3V0_DICPU/4-148                   .........tlqqtysyleqilpiikkeigtvdteikyqkek---------------------------------------........------...------..-----------........IDNVSKLL....KELT.SNIVEF.....E.....N.....Q.....IQQFQNNLNQYS...............EQKAKD.E--SAIKDL....Q...D....E....IDKS............SEEAARLQSEIDRYQKMMD-EL.....AELDPLA.......AE..ITSIIEKIR....GDFDQITNKINSLKENIN--al.....................
A0A140NJL1_PROSM/4-178               ........................................nq--SPLAINSANKKQSSFDLIVQSSCRSVMQQPLVNFTNN.......pSLISLQ...QDVNSA..LGTAKENAKYY........LDTIQPMI....IRNI.SSISAY.....Y.....T.....I.....HNSIASQVPAG-...............--KSIS.DWLNILGAI....R...D....Q....SNKY............ASEANVTSTLLSQFSHKLDNSV.....ASFYDVV.......DR..LNTAILGDN....GALSQNRNNILNIQTQIAA-d......................
A0A1S9AXE6_9BACT/62-213              .............................adlkdfvelidcy---------------------------------------........------...------..-KAINTHCNTW........KKTTYPAS....VDLA.SDIVSY.....N.....L.....K.....VPTYYGAIQKEAdilt.......edpdNAQAQK.ALKAILDNL....S...K....S....AQDK............ADRAGAVYKQVAEFATQTEADK.....ATLLGPDgks.glvKK..YNEKYGTTS....KEVQDLTKQIADEQAIVKK-a......................
A0A073JQZ5_9BACI/44-222              ........................................hl--GAGEFQDVMEKNASSMLVMDSYARTILEEKDVSFAGIn......sISQELK...KSILTH..QVDTRTNATYW........LNNMKPHM....MQVN.NDIVNY.....S.....V.....T.....FQTYYNDLLTAI...............NRQDTN.TLKTKLEEL....H...Y....S....ILNN............KKKTDQLLNELISLRNKMTVDT.....QNLKRDV.......DG..VTTVLTSQD....MGIPLLEQQINRYNDLIKK-s......................
A5N119_CLOK5/38-211                  .........avqayvengtslpksaeemtsklkisaedvnef---------------------------------------........------...SDLINV..YKSIYDHCYNF........KTVVFPMT....VTLA.ANISHY.....N.....T.....K.....VPVYYGALNPIIaayn......ngslsEEDATK.KLTAILTNL....Q...N....T....AQVY............ADDCKTAKENIIQFAEDTKSDK.....SLLDPLS.......DR..YKKAYEGKG....GEIDTLLKEIDNDSKQIKK-w......................
I8UCU6_9BACI/42-216                  .......................................tik----NTLSSSIFKLGSQTPLLTAYGLVVLKQPDVKGTAL........------...TSFVSA..QRVTKNNVKEW........LDEQSPKL....VSLN.QDMMRF.....S.....S.....R.....YAAYQPKLAELAgk..........fdtDPAAKE.SFLNAFNKL....K...V....Q....ASGV............KDDMEQTLVELERYKQLLDKDN.....QNLTAKG.......DK..AIESLNANS....GELANVRAEIKKIEDEIQE-q......................
A0A1C5FAJ5_9ACTN/10-185              ..................................ekqeeigg---------EVAVQGALTALVQTHALSIMQQPKPDFSGId.....neEIRSFQ...GTVQGA..LNNAAENAGHY........LWTVQPES....IALL.SRVENY.....F.....V.....T.....LGALSESLK---...............DEQDPD.AMVQTLRYL....R...E....Q....AGEF............TDQTRKVASSTDSMVSAFSGDK.....REFTECA.......AK..INTLVGGES....GILGDLKRDLENVNSKIT--aa.....................
C3BJ59_9BACI/55-233                  ..........................................SLGPDGLRDAMARTGSNALVMDLYALTIIKQANVNFNGIt......tVDDSLK...TKVVHH..QDVARGNANHW........LDTIKPQL....ISTN.QNIINY.....N.....T.....K.....FQNYYDTLVTAV...............DNKDKA.TLTKGLTRL....S...A....S....ITEN............KEKVDKLVADLKQFRNKMTTDT.....QNFKGDA.......NQ..LTSILASQD....AGIPLMQNQITTYNEAIGK-y......................
A0A073JTG8_9BACI/42-216              .......................................mvr----NTLSNSIRTLGAQTPLIQAYGLVILQQPNVKIDAM........------...SSLTNH..QQFAKNNVREW........MDQYNPKL....MDLN.QEMMRF.....S.....T.....R.....FNSYYSKLHDLAge..........antNEEAKT.NFVSAFNRF....Q...G....Q....VEMI............QYDMEQILLELNRYETLLIQDS.....ENFSERA.......GV..ALQSLQGTN....GDVTQLRADIKRIQEEIQN-e......................
Q81BP9_BACCR/45-224                  .........................................s-ANEARMKETLQKAGLFAKSMNAYSYMLIKNPDVNFEGIt.....inGYVDLP...GRIVQD..QKNARAHAVTW........DTKVKKQL....LDTL.NGIVEY.....D.....T.....T.....FDNYYETMVEAI...............NTGDGE.TLKEGITDL....R...G....E....IQQN............QKYAQQLIEELTKLRDSIGHDV.....RAFGSNK.......EL..LQSILKNQG....ADVDADQKRLEEVLGSVNY-y......................
A0A326U203_9CHLR/46-202              ............................sfmkttkneilyyh---------------------------------------........------...SSLLYD..FKALREHCEDFg......gKDRTYEKS....VNVA.KDIVAY.....S.....E.....K.....AKKSYNEVLQLIdewr......kepskEQEKKQ.KVKDILEAR....K...K....E....SQKY............QRDVEAVYKGVHAFLDITQKDQ.....KALESDE.......SH..YNQKLMKEN....KKLADLNEEVKKLQKEIEE-k......................
A0A3Q9G360_STRLT/9-185               ........................................ia--QQQQLGNAVVQQGGMTAIVQSYALSVTQQARLDLSRSd.....nsQIRAYA...AGINQE..LDRAANTARTY........LNNVQPQS....MALL.AETRSY.....F.....A.....L.....QGAFVDILQQNL...............---PPN.TVAQLLRAI....R...D....D....VGRL............RDKAQQHATSMQGMRDAFGANG.....REFASYA.......TK..LHSVVGGDQ....GILKQLDDQLKQVNAQIQA-n......................
A0A1V2SKP7_9BACI/26-204              .........................................k-LGPDNFQEALKDAGSNVAILDSYAQTILDKELPTLNGIt......sINDELR...GNITKN..LTGAQANANDW........LNDIKPNM....RQSI.KTVVNF.....N.....D.....V.....FQNHYDSMLEAI...............EQKNNQ.KLEAEISQL....Y...Q....S....ILEY............NQKVDVMVEDLMKFRDRLSNDV.....RSLKGNV.......NE..LQTSLSTSN....ADIPLMRKQIEYYNSVIS--sa.....................
C3BUX8_9BACI/4-183                   .........................................s-ANEEQMKKALQDAGMFAKSMNEYSYLLINNPDVSFEGIt.....inGYADLP...IKIVQD..QKNARAHAVTW........DTQVKKQL....LDTL.TDIIEY.....D.....T.....K.....FDNHYGTLVEAI...............NTGNED.TLKKGITDL....R...G....E....IQQN............QEHAQKLIQELTKLKDDIGQDV.....RAFGSHK.......ET..LQSILKNQG....ADVETDQKRLDEVLGQVNY-y......................
A0A077LMV2_9PSED/34-191              ..........................vlnthietpekhynwf---------------------------------------........------...NGLSKS..LDQAKLNAQEW........IDDLAPEL....TGGVpLQVIDF.....G.....T.....T.....FDSVMGLIVKQVesnp......samgaSDPTVV.KISLLVKML....N...D....E....VQEA............IHKADTTAERLRAWGNKMQRSH.....NELVSSV.......SS..IQNAETELL....GHVQELNAAISGLNAMIA--ae.....................
A0A1H7IRI4_9PROT/48-193              .....................................pswfd---------------------------------------........------...-DLNAK..LDAAKVLANQW........IDDMAPKL....TASVpSHVIDY.....G.....T.....T.....YEALTDQIIDLLnknp......nargkDDPVVQ.QVFALISAL....H...D....E....VETI............ITDVIGTQEQLKTWGDAMQKSH.....DDLFAGA.......AN..IQSLQIDLQ....ADIGKMNSAIQGLQAQID--ae.....................
D8Q4J7_SCHCM/47-215                  ...........................ddyqkrlqistdiat---------------------------------------........KLSNVI...TPLVAA..YKTCSANCTTF........KTTTYPSI....VAIA.SDIYSY.....AqnaggT.....A.....QDSYYANIWQGIrslan.....atsptQAQQLT.DTINGLIDV....Q...V....T...dIANI............KAKAEQVVTDLTTFKTQTEGDQ.....TTLKTNL.......DA..VAAALKAED....GDLATLEKLLVDN-------kaelasd................
A0A0T9L222_9GAMM/5-178               .....................................qtaln------INSSNKSQSSQAIIIQGYCNSVLEQPEVDFSYD.......tSLNDYQ...QKINTS..LGTAQTHASYY........LNTIQKQI....ISNL.SNIGNY.....Y.....A.....L.....HQAVPESVPENA...............---TSQ.DWITVIQAL....L...T....T....SQKY............ESECNNTSSLLSTLSEELSRDT.....GNFDQIV.......TE..LNAALNGNN....GVLDSNRKQIASLDTKIAG-e......................
A0A069PJF8_9BURK/13-186              ....................................asidvq-------REKVKAQSAAGLILQAHCLSVEAQQAVSFEGF.......eKLQDCK...VRANKA..LDTAKTHARTY........LDTIQPKI....ITTI.TSIEEY.....F.....L.....L.....QRAVGDALAS--...............-LQSRE.DAKTSIRLL....Q...E....R....VAEF............KNHSVSIRTSLESLRTGLANDQ.....AAFSGLA.......TE..LNGLLQGDK....GVLAEINGQLSSIDGKIA--gv.....................
A0A1G6J653_9BACI/46-223              ........................................el--VPAELENVLAKTGSHIAVLDEYAILVNAQAPYDFSAT.......sIDKGLI...DKIVAD..QQTAKANAIKW........VDQVKPQI....IQTN.EDIFAF.....G.....T.....K.....FDKYYETLVRAA...............DEADTS.KLKSGITSL....Y...K....S....IQNK............QNDVTDLIGVLKTYRNAVVDDG.....ENFSTNA.......TN..VAKAFDANT....GKIEQLQDLIAEYQKNID--eg.....................
A0A1U9JJ99_9NEIS/42-196              .........................................p------------------------ANSTLSQPQIDLIMV........------...-AIDKH..FDNAKNLATQWesgtplleANPIKDQV....TGVF.LGFQRF.....A.....R.....H.....MDVEYKILIEAA...............YANDNS.HIADKLRRL....K...G....T....LEIL............LAESKGAKTSVAEYQSQLADAL.....SAFEKDY.......QN..VLSELGTVS....GAISGLKAKIESLQNNIAE-n......................
A0A1B6AEI3_9ACTN/8-166               ............................avdqaarnvrdsqv---------------------------------------........GDASAV...PGLQEH..VDAAKSHAGSW........LNKTRTSVgeplSLTR.SLVSSY.....L.....G.....T.....DARRLAELTPRAe............agDQAARD.EFVTRLQRV....K...S....D....LDTF............QQRVTANTAEVNELNRAFTTDA.....SRFAEDL.......NT..ISAVIATDQ....RMAEELRHQAQALRDKIA--da.....................
G7ZI37_AZOL4/95-285                  .......................................vll-------TKSKMATGVTSIVLITNACHAILNTQLTLPDG.......mTKPTWF...DNLVTK..LDAAKALATEW........INTLAPEL....TASLpNKVINY.....D.....T.....Q.....YNAITNQIIRIAdahp......margaDDPNVK.LVFELISAL....K...T....E....VGKI............HDDVAAEDKKLLDWGTRMQKAH.....DDLSQGVtsiqaaeAD..LAADISKMD....GDINRLKAEIDGLNKKIA--aa.....................
A0A0W7YA76_9BACI/47-233              .........................................e-LGPEGLKKALAETGSHILVMDLYAKTMIKQPNVNLSNIdl....gsEGGELI...KNIHLN..QDLSRINANYW........LDTAKPKI....QKTA.RNIVNY.....D.....E.....Q.....FNNYYDTLIDIV...............QKKDRE.GLKEGIGDL....I...S....S....IHTN............SKEVTEVINILENFKTKLYTNS.....IDFKNNVggp.dgkSG..LTAILAGKE....ALIPQLHAEIQQLSSTQKD-h......................
A0A2B4SMG0_STYPI/704-875             ...............................qltvsqkdvfd----------------ASAAIQTYVAAILRQPDIKLDQL........------...PDLPNF..QKTARQHAQNW........LDQVLPAI....ITTN.ADIIDY.....A.....N.....G.....FASFYRTLVKLAeki.........dtgDKSQLK.EFTQGLVLL....R...N....N....LNRK............DEQAKYTEIQLQNFKAEVSVDH.....EHFNKEA.......TK..VTKKLEGSD....GDLAKISSRIDTIDGQLH--ty.....................
A0A1V2SK11_9BACI/46-224              .........................................q-LGPDGLREAIKTTGSNALVMDLYALTIIKQPDINFKNVs......vIAIPLQ...TKIVED..QSNARENAKTW........LDQLKPQL....IQTN.ENIINY.....D.....N.....K.....FEGYYEKLLEAA...............DQKDPA.ALTARLTRL....S...D....S....VMEN............KQAVDKLIVDLKKFREKLESDT.....KNLKAHT.......NE..ITTILASQE....TGIPLLKNQIETYYDAINK-y......................
A0A2B4SHY1_STYPI/6-139               ......................................sfhs---------------------------------------........------...------..--LARKHALHW........QESVEPTI....RQCF.TDAMNF.....S.....K.....A.....FSGKYYHLNSFIdqm.........kngNQQAKD.EFTTTFRNL....T...V....Q....LGAV............VGHSKDITTEVRQFSETLNQDT.....RNFKSDS.......EE..TQTKIIGNN....GDLKALQDQQDGINKAIN--rd.....................
A0A182VI53_ANOME/15-146              .....................ilwtqgtgrkqispkmteqaa---------------------------------------........------...------..-----------........------RL....QTHN.QEMVKC.....L.....N.....Q.....LRSQQTALEEKIa.............aQEKKKD.SLSKEMEKL....Q...R....T....LEQL............ETSIAEDTKALNDCSKRLTETE.....NGYAKVV.......DT..LQLLLMSAK....EKVNTT--------------tptsrsvynesskh.........
A0A2N1A316_9GAMM/58-248              ...............................sdtsllsttew------------------YQIQAYATAAISLPTTEASLRtlt..kfpVNDAFTyeyESLLTE..FTNIHRSGNDW........NSTIYPGI....VDLA.LQLANY.....G.....D.....I.....HPQLILPLMDQItqlqtna.imgnltvAATNRD.AALSFLGVL....Q...S....F....TSAQ............QQATSNAVEELKQFAADVEAQK.....AQLDVIE.......GN..FSTLLNSE-....-TISTLRENVRLLNQEIAG-y......................
D8Q0V9_SCHCM/44-212                  ..................................aqsyqerl--------------------------------DISTDTM.......vKLEGVL...KDLVAA..YATTKSHCVPF........KDTTYPSI....VSLA.DDVYSY.....AqnaggT.....V.....DDSYYAQIFKLIrql.........psaQEADQA.QIRQSINGL....I...DvqlaN....VDAI............VTKVAATVKALTDFENECMSDQ.....STLTTRN.......KA..VKDRLDTEV....GQLAQLETSLDSNR------riirad.................
G8MGH7_9BURK/12-186                  .....................................easid-----GQREKVKEQAAAGLILQAHCMSVEAQPLVSFEGV.......eKLEAVK...VRANNA..LGVAKAHARNY........LDVIQPRI....ITTF.TSIEEY.....F.....L.....L.....----QRTVTEAL..............aDIQSRE.DAKTIIRLL....Q...E....R....VAEF............KSQSVSNRTALETLRTNLAEDQ.....SAFKGIT.......IE..LTGLLEGDK....GVLADITGQLSSIDGKIAG-a......................
A0A0D8CW88_9GAMM/67-249              .........tiqayvqealrlpitqsamvsafaipssvafsn--------------------------------------F........------...QALLNE..YKLIHATANDW........NSSIYPSV....VNLA.LKLGNY.....A.....D.....I.....HRLIIAPLIDSLmamkeaa.qandpiaGEAQRN.TAVALLTML....Q...A....E....AQTR............QAETAKAESDLLGFAADIARQS.....GQLDQLR.......TT..HSEYLQDDG....S---ALKSQIATLNAR----vrqlnadydh.............
A0A1C7MIT9_GRIFR/59-222              ...........................rlalsdygynklssd---------------------------------------........-----L...SSLIDA..YKITQGQCEEF........KDKTYPSV....VALA.DDTYDY.....A.....Q.....NaggegADSYYGNIFKAIrel........atqaDPQKQA.ELKANIDAL....V...N....AqveaIGKL............QQNAANVVESLKTFEENTKKSQ.....DNLKTRQ.......AD..VETKLTSAN....GEIKTLQAKIDTQVNQIR--ed.....................
D8Q5Q7_SCHCM/48-214                  .....................................ytqrl----------------------------------QLSDDt.....agKLSDVI...KPLVAA..YAVAQTNCQVF........KDKTYPGI....VDLS.SDVYNY.....AqnaggT.....V.....EDSYYVNIISWIkql........sqstDKDEQE.DLHGAIDAV....I...D....QqleaIQAL............QDRADAAVGELAKFEDQSEKDQ.....DALTTRS.......NA..VKDKATAEV....GNLDDLNAKLKEYRDEL---tdd....................
A0A1I3AW30_9PROT/52-196              ......................................swfd---------------------------------------........------...-DLNAK..LDAAKVLANQW........IDDIAPKL....TASVpSHVIDY.....G.....T.....T.....YTALTDQIVDLLnknp......nakgkDNPVVQ.QVFALISAL....H...D....E....IETI............ITDVIGTQEQLKIWGDAMQKSH.....DDLFAGA.......AN..IQSLQVDLQ....ADIGKMNAAIQGLRAQID--ae.....................
A0A0F7G0M4_9ACTN/6-187               .......................................vva---AEEVKQDLADYFNASVEVNTYAYNVINTSMPNLKRP........--PAHY...ADFVAK..FALARSHCLSW........GQGTMGQI....IDFP.GEIVDV.....D.....N.....L.....FEDEADDLSQALdali.......knpaNEHAKD.QLRESLKRM....R...S....T....VQRK............AGTADKLVATITRFRDDVKRDA.....ADLATIA.......DA..SLQDATSDA....DTIREVNSEIEQLNNDIQ--t......................
W4LPM0_9BACT/9-201                   ................ptddiqqalagaflaiqsankaiatq----------------------------SKMPPVNITGL........------...EDVNTS..LATAQAHAAHY........TKNISANI....QNQL.QAIIDY.....D.....R.....L.....YDALVVSIDSLIteigqg...tkanppSDATMN.NLAAELAAL....Q...S....Q....VQTNlygaggtadlplEASALGVYNQLVDYQAQVGTDA.....STFKGYS.......DL..AYNSESGVS....AHIKQLNQDIEADRDAMAK-d......................
A0A014MG07_9GAMM/4-177               .....................................atdvs------MDTSMSGQASQALQIQNYCNSVKQQIPVDFSQF.......pNLQNFQ...TEINQG..LSTAQDHANGY........LNTIQPQI....ITNI.SNISNY.....F.....A.....L.....QNAVPATLPPGS...............---TKE.QWLSTLSMM....K...D....Q....ATEY............QSLSVSTKNVLVVLNNNLVIDS.....RNFQQIV.......VD..LNTQVNGDN....GVLEQLNTEIDGINSAID--ga.....................
D8QBU9_SCHCM/72-235                  ................................rvpvsndvkd---------------------------------------........QVSGLL...KPLLES..YARAKGHCTTF........KQTTYPSI....VGLA.SDVYDY.....A.....QdaggkT.....QDSYYANIVSSIktl........atatSQEQKD.NLVETIGSL....V...D....MetqsIDQN............IGNAQTAMQKLQEFGRQMKKDE.....LVMRESE.......NA..IISKLKDII....GDADELQKKLERCREKLA--ae.....................
R4L9T5_9ACTN/6-182                   ......................................plqr------LEPAVREGFAAYLRMSGDATAIVNQQNLSLALV........------...PTLAED..QALARAHAADC........VVTRAPQM....LVAL.TAVAGY.....A.....D.....T.....VQAFTPALSREAdv...........vdAGGDPR.RLLVLLGAL....R...R....Q....LSVE............ISDLAATADSFGVFNQSAADDV.....TRFRQLSrg...vpAA..YGLELARLQ....ERLDTLRQRLEDDNKTI---tga....................
Q81EZ8_BACCR/41-216                  .........................................v-IAPNTLSNSIRMLGSQSPLIQAYGLIILQQPDIKVNAM........------...SSLTNH..QKFAKANVREW........IDEYNPKL....IDLN.QEMMRY.....S.....T.....R.....FNSYYSKLYELAgn..........vneDQQAKA.DFMSAYGKL....Q...L....Q....VQSI............QESMEQDLLELNRFKTVLDKDS.....NNLSIKA.......DE..AIKTLQGSS....GDIVKLREDIKRIQGEIQA-e......................
A0A1G6J8N4_9BACI/41-227              .......................................dtk----NQLEAVIDQLGAQSVSMQADALTLLQQPNMSIADM........------...PELSKY..LQRTKESATNW........LDTLNKRV....LKTN.QNMMAF.....G.....Q.....D.....VESYYDTLSDLAtr..........vneDEQARA.DFARGIQYL....Q...S....V....LADD............QNETNETMAQLADLRQTSDYTF.....DKFSADV.......NEslTQSSSKTQEa..nRHIVALTIKIQ---------qnrdfmiasklqrledf......
A0A3G3GSJ1_9BACT/13-182              .......................tasvqttgtsigsinaacq--------------------------------NVQIMPT........YSSPYA...PSLQQD..ISNAKAVANQW........TSDILRQV....MASL.EGIVGF.....N.....D.....L.....FQSVFNGLYNIAeai.........akgDTTQIA.QFQFFLSAL....Q...Q....A....TQAQ............ETQVNSTQTALTNYLIQVDNTM.....RALNNDN.......LQ..LQNAVNSLN....AQMRSLEQQMSDVQRKINE-e......................
D8Q589_SCHCM/40-211                  ..............................llptdaksyqeh-------------------------------LNISTDTM.......vKLEGVL...KDLVDS..YATTKSHCVPF........KDTTYPSI....ITVA.DDVYNY.....AqnaggT.....V.....ENSYYANIFQMIrq...........lpTASDQQ.GTLKSINGL....IdvqL....K...sVDTI............VTKVAAVVSNLTAFQDQCMQDQ.....SSLKERQ.......KA..VTDRLDTEV....GQIQQLEDDLASNRRIIK--ad.....................
R4LLT0_9ACTN/12-183                  ........................................vp--SPGTLTEATTAVTAAKITVDAYANAVINQPALHLDKL........------...PDLAGH..LTTAQGNATTW........VEHTSPEL....VNRI.TDVIGF.....G.....D.....I.....WAAFMPTVRQKV...............KHGKKA.DVVQLLQIM....R...D....N...hLQPL............EQAAKDSAAAVSSLGVAFAADD.....GNFTTDL.......QL..GTSVYEGDQ....GVIAQLQKANSDLQNSMSH-m......................
A0A1V6P0T9_PENDC/65-235              ...................eyirrmdidqeavgtvsneidlm---------------------------------------........------...---TAA..YKDIKTDNINF........RDHTWPSL....VDLA.ATISDY.....AkdaggD.....I.....DSSYYANILTAVkdyndak.rekkqeaMEEAKE.TILGFTSAL....I...G....S....ITKL............QEASAKAKDDLATFKNLTSNHS.....LTLKANR.......DE..VKKLFEGST....GEIARLENDIKELQEELE--gd.....................
C3BJ60_9BACI/69-247                  .........................................s-LGPAGFQDVMAQTTSSVFAMDAYAKTIRDQQETDLSKIs......aVNSSLR...ENMIKH..QKEAKLNAIYW........LDEMKPQI....LKTD.QNIVEF.....N.....D.....T.....FQAYYNNLLAAM...............DQKDSG.KLKSDLEKL....Y...N....V....ILNN............QSEVDKLLGNLKTFRNRMAEDT.....KSFKDDA.......NQ..LTSILASTN....AGIPLLQQQINTYNDSIKK-s......................
F4KUV6_HALH1/16-197                  ........................................ns--SIKDLREAVLGSGSAGLVVQTYANTILQQPDITLPAD........----LL...AKIPVDvfLKTARTHADNY........LNNIQPGI....INTI.QDVNGY.....S.....T.....Q.....FSSFNKVISQSIntw........kmgnNLTAKQ.EALDLLKQL....Q...I....G....LTSK............QNKVILVSKDLGKLLLDLNGDV.....ANFTTAV.......ST..ADIEIGADS....KVIGDLENTISSFDSKIAG-a......................
D8QB82_SCHCM/52-215                  ................................rlgissttmq---------------------------------------........KLNAVL...ESLISQ..YKTTQQHCQPF........KDTTYPSI....VSIA.DDVYNY.....AqnaggT.....S.....TSSYYANIFAAVral........gkttDPDQIA.SLKQTITELvniqV...K....N....IGDI............TTKAQAVVDDLTDFQNLAMQDS.....TNLQARH.......TA..VTDALNTEI....GNLAQLKQNLSD--------drtllkad...............
A0A1H8U6W1_9SPHI/73-201              .......................................dic---------------------------------------........------...------..--------DTF........DTVTKPDS....VKCA.SNLIAY.....N.....V.....K.....VPIFYRAILALLlkie.......adptDTVSIN.QLKQTLQVM....I...N....E....AQAF............STHATNVAAAMQKFSLDTSVNE.....AAIGTLF.......KT..YSDKISGTS....GTIKTMQAQLAQ--------dkadlada...............
A0A1M7IPT0_9BACT/13-190              .....................................tpqql-----------TDYANALIVVNSYTYAVENQQLPTLNAP........--PTNY...ADFISA..FNPVKSSAINW........SETIFPSI....TTLP.AHIINY.....A.....G.....S.....LFNLEETLVTGYlnil......indpgNVAARN.GLVATLTNM....Q...Q....T....IQAE............LNFVTDIQSNLTAFTTDTQTAG.....QTLQQLA.......QQ..ALSMAGADK....TTIQSLNSQIIRLNNDVAN-a......................
A0A1V2SKA8_9BACI/31-205              .....................................dltsi-----TFSNWIRTLGSQYPLLQSYGLVILKQPNINIKNM........------...SSLNNH..QQIARSNVREW........LDYYSPKL....IYLN.ESLNSL.....S.....Q.....R.....TDQYYNRLYQLAgq...........idNEQEKK.EFLNRFNRL....Q...D....T....VEDI............QISMQNTSTDLNTYKGLLISDN.....QALAERA.......EK..AIHELSGDN....GEAVKLGEQIKKLLAEIQE-e......................
A8PME4_9COXI/58-232                  ......setqciseanfaqgsvvqnyciatttqsliippdee---------------------------------------........-----F...KDVPKI..QQNAQEHANFW........LSGLNNKV....VGIN.SGLKQY.....C.....S.....L.....IMTYENDMDNLVdev.........vndVSGAKD.NFLNQIGLL....R...D....Q....ANTR............EQKIIVITNELGSFRKYIGQDG.....SNFKSIQ.......SK..ADIKYNANT....GEMKKLKDTIDALNASIQA-a......................
A0A1B6AEA3_9ACTN/18-186              ........................aatealftayqlttaaai--------------------------AVTEQPSLALELV........------...PTLAQT..QDLARSHAVTW........GHAYQTAL....LQPL.TDVQGY.....T.....G.....T.....FISFTPHMDDLArra.........gdgDATAQA.EFRQGLTIL....R...R....L....VSQN............EAGVTAAKGEIEQFKQLVDDDR.....VRFGSDG.......KA..LEKRYTGPD....GEIAEIEKNLAALDSEL---ret....................
A7GNS4_BACCN/41-216                  ........................................vm--TPNTFSNSIRMLGAQSPLIQAYGLIILQQPDIKVSAM........------...SSLTNH..QKFAKANVREW........IDEYNPKL....IDLN.QEMMRY.....S.....I.....R.....FNSYYNKLYGLAek..........ineDEQAAV.DFTNAYGKL....Q...G....Q....VQMI............QDNMEQTLFELNRFKALLTKDS.....QSLSQKA.......DE..AIQSLQGAN....GDIVKIRAEIKRIQEEIQT-d......................
C3BVE6_9BACI/1-174                   ..........................................------MKTALQDAGVFAKSMNDYSCLLINNPDVNFEGIi.....inGYADLP...IKIVQD..QKNAREHAVKW........DTQIKGQL....LDTL.TGIIEY.....D.....T.....K.....FDNHYGTLVEAI...............HTGNGD.ILKKGITDL....R...G....E....IQQN............EEYAQKLIQELTKLKDDIGQDV.....RAFGSDK.......DL..LQSILKNQG....AAVEDDQKRLNEVLGQVNY-q......................
Q813Q6_BACCR/46-224                  .........................................s-LGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQETDLSKIs......sINSEFK...GNMIQH..QRDAKINAAYW........LNNMKPQI....MKTD.QNIINY.....N.....N.....T.....FQSYYNDMLIAI...............DQKDSG.KLKADLEKL....Y...A....D....IVKN............QNEVDGLLGNLKAFRNRMAKDT.....NSFKEDT.......NQ..LTAILASTN....AGIPALEQQINTYNDSIKK-s......................
A0A238VAM4_9FLAO/16-188              ..............agwsslhiitasclavqnttftapnpkp---------------------------------------........---DWF...DSLNSA..LVNAKTVAADW........VDNLSVEV....TQSIpTAIADY.....G.....T.....D.....YAAFSQKIRDIAtqyp......datgaNDPHVK.QVNALIETL....L...A....A....LNEI............LSSVDKVSEGMKTWGQQMQSAH.....DNLTTGA.......AN..IQSAEVELR....ADIDKMNTAISNLHKMID--ge.....................
A0A0W7YA82_9BACI/35-207              .....................................qeenv-----ALSSSLRKLGAQSKLIQMYIDKALMNPNVQLEEV........------...PALNTE..QFLIKQDMKEW........AVELYPKL....ILLN.SKSKGF.....V.....T.....K.....FQAYYPTLKEFV..............dTKENKE.GFLDRLEVL....Q...E....M....VLTN............EESVQYQMNELTDLKLQLDKKL.....KNLDTDV.......IK..AQEVLSAEG...tGKIDKLKAELLNTKKSIHN-d......................
Q9KL64_VIBCH/12-189                  ........qqttqsaflattvitaqchailntqftpptvkpd---------------------------------------........----WF...DDLSKK..LDSAKLVAKQW........IDDLGPQV....SASIpSSVINF.....D.....A.....T.....FQASIDAIHELYkadp......tasgkDNTTVQ.QASQIMTAL....S...S....Q....VSGI............EATVKGMNKELSDWGVKMQAAH.....DDLVNGA.......TN..IQKTIIDLQ....TDIESMNNAIDNNRAAIEK-l......................
#=GR Q9KL64_VIBCH/12-189       SS    ........HHHHHHHHHHHHHHHHHHHHHHT-EE---SS--T---------------------------------------........----TH...HHHHHH..HHHHHHHHHHH........HHTHHHHH....HHHHHHHHHHH.....H.....H.....H.....HHHHHHHHHHHHHH-T......T--STT-HHHH.HHHHHHHHH....H...H....H....HHHH............HHHHHHHHHHHHHHHHHHHHHH.....HHHHHHH.......HH..HHHHSCCGH....HHHHHHHHHHHHHHHHHHH-H......................
A0A3G3GSG2_9BACT/6-184               ...................................saapiav---------ATANIATSSILLQNYSQAISNQPEVTLESV........------...PEFTED..QKSVQQNALFC........LNKITPEL....VALS.AQDIGF.....A.....N.....E.....FLQMYPRLLSDAqlidda...tadanaRTNATH.DFCAGVNQL....I...I....T....INNG............TATRNSMARDLTQFIDLSASNQ.....TDLDADL.......EV..AQKQLLGN-....-DITKLQAQLATIQQAID--sd.....................
A7GNS6_BACCN/40-218                  .........................................s-LGPAGFQEAMVQTTSSIFAMDSYAKLILDQQETDLHKIn......sIHGDVR...RDIIQH..QRDAKMNATNW........THQMKPQI....MKVD.QKIIDF.....H.....T.....I.....FQAQYNSMLLAV...............DQKDRD.TLKANLETL....Y...T....N....ILRN............QKEVDALLEELKAFRERMVKDT.....TRFKNDA.......DQ..LTAILASTN....AGIPALEQQIQTYNDSIKK-s......................
A8PKF9_9COXI/30-206                  ......................................vias----ALIKENMGNVHTNSSLVQTYIAACLTQKNIKLDKI........------...KSIEKT..QEETREHARYW........LNSLVPKI....NATY.TDVSGF.....C.....N.....L.....SSSYWEDLIKLAaei.........qnaHDENAE.NFKLGISEL....K...D....N....IQDK............ENKTQSLINKLALFRTDLESDN.....RNFQAIV.......TD..ADRIYAGSE....GELQMTRKNIDALSSAIDK-d......................
F4KUV7_HALH1/16-197                  .........................................d-LAPDFLSQDTNDAGANILLMQIFANLALQQPDLSVNLT........KNQDIL...INLKQH..QKLAKRHGAYY........LNTVQPGV....LQIM.VDLLGY.....S.....S.....M.....FQHFKKQIDQLIss..........vhsDPEAKK.SVLALLSEL....E...R....T....ALQK............QINAQTTVGILRNYALQTALDE.....TNFKADL.......DE..ADKVIGSDN....GHLSDIKNEIADAQQQIKG-n......................
D8QG72_SCHCM/49-221                  ....................................srlqis-------------------------------------NDv.....ftKLSDVI...KPLVQA..YAVTKEHCKVF........KDTTYPGI....INIA.SDVYNY.....A.....QnaggsS.....QDSYYGKLWFLSlpyifqcirkldhvtSEEEKA.RLIKTINEL....V...D....MqvknIDKI............CTKSQAVVADLRTFHDNTRKDQ.....SILQERS.......TA..VHNKLKAEV....GSLDDLETKLQNYRIELN--nd.....................
A7UVL7_ANOGA/1-117                   ....................................mteqaa---------------------------------------........------...------..-----------........------RL....QTHN.QEMVKC.....L.....N.....Q.....LRSQQTALEEKIa.............aQEKKKD.SLSKEMEKL....Q...R....T....LEQL............ETSIAEDTKALNDCSKRLTETE.....NGYAKVV.......DT..LQLLLMSAK....EKVNTTTPTSRSVH------sesskh.................
A0A1C7MQ73_GRIFR/152-315             ...........................rlalsdygynklssd---------------------------------------........-----L...SSLIDA..YKVTQGQCKEF........KDTTYPSI....VVLA.DGVYNY.....A.....Q.....NagggeADSYYANIFKFItdl........aketDPQKQA.DLKKNINTL....V...D....TqvaaIGTL............QQNAANVVQSLKTFEENTKKSQ.....DNLKTRH.......AD..VEAKLTSAN....GEITTLQAKIDTQVNEIR--qd.....................
Q7BYC6_BACCR/44-230                  .........................................a-LGPEGLKKALAETGSHILVMDLYAKTMIKQPNVNLSNIdl....gsEGGELL...KNIHLN..QELSRINANYW........LDTAKPQI....QKTA.RNIVNY.....D.....E.....Q.....FQNYYDTLVETV...............QKKDKA.GLKEGINDL....I...T....T....INTN............SKEVTDVIKMLQDFKGKLYQNS.....TDFKNNVggp.dgkGG..LTAILAGQQ....ATIPQLQAEIEQLRSTQKKH.......................
A0A0F7RFS4_BACAN/54-232              ..........................................SLGPEGLKDAMERTGSNALVMDLYALTIIKQGNVNFGNVs......tVDAALK...GKVIQH..KDTARGNAKQW........LDVLKPQL....ISTN.QNIINY.....N.....T.....K.....FQNYYDTLVAAV...............DAKDKA.ILTKGLTRL....S...S....S....INEN............KAQVDQLVEDLKKFRNKMTSDT.....QNFKGDA.......NQ..ITSILASQD....AGIPLLQNQITTYNEAISK-y......................
A0A1H0Q479_9ACTN/12-186              ....................................vnqqsl------LAKSVAEQNVKSLQVQRYAVAVQQQPRADFGTAd......kRLTERA...RLINRE..LESANRAVAHY........LAEVQPVS....LRLV.TDAQAY.....F.....A.....L.....QDNV----LASL...............TGMRTE.TAIRMIDVL....E...R....K....TREY............SREADAVSREIGKSQSTFSENA.....KEFREHA.......GE..INKFVSGDN....GLLKTLQDDLDQVESSINHH.......................
F4KUV5_HALH1/5-154                   ..................iknvvqlaqsiqsqdillaqtpai---------------------------------------........------...------..----PQHVGAF........IQNVAPEA....QDDI.DATNKF.....I.....S.....A.....YRQAKSSIDTAIaaw.........rggSDEART.QALNQLQGL....S...T....F....VQSA............TSANTKVFQDLSSFKQAFSADE.....EQLGGVL.......NQ..INAQISAIQ....AGIQDQQNTLAQE-------katla..................
A8PKF7_9COXI/22-202                  .........................................s-LSPADFPIALDQLMSTQCLSQAKSIVLLLQKNVELNKL........------...IAIKTL..QTKMRDIARSY........LDEYIPQI....LSLL.TDISGF.....Y.....N.....F.....FSSYYQDIYELIhslne....tsdeneKNGSIT.DISEAIHDL....H...S....F....TIKK............QDKANALVTDLEQYRDDPQKLE.....DTLNNTQ.......KT..AEQLYVGES....TEIKALEASLHELSKEIN--v......................
I8AGD4_9BACI/45-223                  .........................................s-LGAGEFKEAMQTSNANALALDTYAKMILEQKELDLNGIr......dVNNSLK...SRITTH..QSNVRGNASYW........INTIAPKM....SATT.QGIIAY.....S.....K.....T.....FHEAYDTLVKDV...............KKKDAN.ALASHLGNL....M...T....S....VSEN............KAKTDELISLLSQYRSSITSDT.....QNFKTDA.......EE..ITTILAAND....ATLPLLQNEINQINGSIKK-g......................
D0LUR3_HALO1/94-266                  kiqvyaetalrlpideptmrlvlerdpaesftdfvplltayq---------------------------------------........------...------..--ATHAHAVDW........DQNILPTS....VELA.VDISNY.....A.....D.....K.....AGIYYGPLQQAIaavv.......adssDVGSRA.LVEALLNDL....A...A....D....AVEY............EAAALEVQNDLNAFAVQLNSDR.....GALSTLV.......TE..YQQSHGATG....EEVEELREREAEIDA-----lidq...................
A0A073JT53_9BACI/55-232              ..........................................SLGPEGLREAMERTGSNALVMDLYALTIIKQANVNFNGL.......tVNDALK...TSVLHH..QNVARINANQW........LDTLKPQL....ISTN.QNIINY.....N.....T.....K.....FQNYYDTLVTAV...............DNQDKE.TLKKGLTRL....S...T....S....ISEN............KQKVDKLVEDLKKFRDKMTTDT.....QNFKGDA.......NQ..ITSILASED....AGIPLLQQQITTYNEAIGK-y......................
D8QBX6_SCHCM/48-214                  ..................................qtrldisd------------------------------------SAM.......tQYATVI...DNLVDE..YKTVSAHCNTF........KNTTYPAI....VNIA.ADVYSY.....AqnaggT.....V.....DDSLYASIFQLIrsfa.......ntsnTTDDKN.KITQQVDDL....I...N....VqvqaIAGI............LTKAETAVTDLQNFETQCMQDQ.....SDLQARQ.......KA..VEDAITAET....GSLADLKARLQSDRQT----laad...................
Q7BYC7_BACCR/45-224                  .........................................s-ANEEQMKKALQDAGLFAKAMNEYSYLLINNPDVSFEGIt.....inGNADLP...SKIVQD..QKNARAHAVTW........NTQVKKQL....LDTL.TGIIEY.....D.....T.....K.....FENYYETLVEAI...............NTGNGD.TLKKGITDL....Q...G....G....IQQN............QKSAKALIEELMQLKNAIGEDV.....RTFGSHK.......ET..LQSILKNQG....ADVEADQKRLEDLLGQVKY-q......................
A0A3G3GSP0_9BACT/8-192               .......................................nig---SSDVQTGMSNSMSASIMLQTYTNTVLQTPDIKLPSQvd....tdSKSTVV...EDLPAH..QALARTNATYY........LNTLNPLI....VNTI.ADVIGF.....G.....N.....L.....WSAEYSLLYSLAe............siDQGDNAnTFTQGMNNL....I...N....K....TQKA............EASTQPVIDALNAFLPLIQTDE.....RNFNQDA.......TN..VNNALGGEQ....GEIAQLQKEIAAYNTAMNK-d......................
A0A077LYS1_9MICO/10-184              .......................................kaa---VDAISNANRSQCAVGVQMQAYCNGVLEQPTVSFRGF.......tNLATYE...SQVNAG..LSAAKDRANYF........IDTITPTI....LTNA.VEIGNY.....L.....D.....I.....HGAVPVALPAGS...............---TKA.EWLSALASV....R...E....E....ANAK............AERASQVVRSLSTFHSGLTTDV.....AAFTRTV.......TE..LNAVVNGDN....GVLDSLNQQIEELQGKI---ggt....................
A0A0N8W5T9_9SPHI/30-213              ......................................ewlg--------------------IQTFISTAQQLPTTKATMDatlpakpsGTDALF...AKLLTA..YKTLKTSCDQF........EKITLPDS....VTCA.SNVVTY.....N.....N.....K.....VQTYYPALIKELekynedattaaeiaaNETIMK.RFAAVCDLL....I...R....E....AAKH............HEHAQKVYNALKSFSAETLVSR.....QDIVNLH.......LE..FSNEFDTEE....GVIAKLEKRIKFIKDLI---del....................
A0A023BTX0_9FLAO/6-175               .......................................pti--------EAAKTQTTQGLVLQGYCNSILQQPFVDFSEF.......tNLSKIQ...TNINDG..LQNAKDNAKTY........LNGIQNNI....ISNI.NSISNF.....Y.....N.....L.....YSAVPTVLPPDA...............---TEA.QWLSILQAM....K...S....Q....TDTF............IEASDLVIIDLGNLNSNINADV.....AFFNKTI.......ND..LNAIVGGND....GMLASLDKDIERLDKQIA--gt.....................
A0A3N7AAG7_9BACT/48-206              ........................svlntqfvpftpkpkwfd---------------------------------------........------...-DLNAK..LDAAKVVAGVW........INDLAPKL....TASIpNQIIDY.....A.....T.....T.....YDAMTTQILALVdkdp......margkDNPIVQ.QTFALIDAL....S...N....E....VDKI............IKNVVAMEDKLKNWGKDMQKAH.....DELSSGT.......TN..IQNLEIELQ....SDIDKMNNAITNLRTQIDG-e......................
A0A2S1LRP1_9FLAO/68-213              ................................mtpfnplika---------------------------------------........------...------..YKDIYDHVKVW........QDDTFPQS....VSLA.SDVVAY.....A.....Q.....Q.....APTYYNPILPLAqklt.......tnpdDQPTKD.KLKAILSVL....T...N....S....ANGY............QKKAVEVASKIKTFADETMSDK.....IVLVGTDgkt.glfKT..YNDQYGATS....ADVVELNKQL----------vaqqlv.................
A0A1B6AEW6_9ACTN/14-187              .....................................gtngl------LQQHAQHTGAHRALVDTYATNVLEQPAVKLDKL........------...TDVEKY..QTSAKAHATSW........RDSVSGLL....IGAN.TDLMSF.....S.....N.....S.....FTSFYNPLMSMAqn...........itAGDNRA.QFVKGLQIL....V...S....Q....IEDK............RTKADGALDALKSFRNDVADDH.....GHFLELA.......AK..AKSLYEGDK....GVISQLENRQDAIRQAMS--td.....................
A0A1I4QEG0_9PSED/13-184              ....................................ygqtri---------ALKRQSSAAMLVQAHCLGVERQPAVDFGDQ.......eRLKPLQ...NEINSG..LVKAKQSTTYY........LNDLQPRI....ITTV.ANIEAY.....F.....G.....L.....HNTLAQMLLPTT...............---SST.AAIAMLREM....E...S....N....VEVY............RRQASIIQTDLSKMRTGFSDDK.....AFFDRCT.......ID..LNALVNGDQ....GVLVSINGELSGIDGKIA--gv.....................
A0A1C7MI70_GRIFR/79-249              ....................tmqeykdrlalsdygynklssd---------------------------------------........-----L...SSLVDA..YKVVHDQCEEF........KDKTYPSV....VALS.DDAYDY.....AqnaggE.....E.....ADSYYGNIFKAIrel........atqaDSQKQA.ELKANIDAL....V...D....TqveaIGKL............QQTAAGVVQSLKTFEENTKKSQ.....EDLNTRQ.......AA..VETKLTSVN....GEISTLKAKIDAQVNEIRK-d......................
A0A3A9EJH8_9FIRM/1-77                ........................................mn---------------------------------------........------...------..-----------........--------....----.------.....-.....-.....-.....------------...............------.-----YEEL....Y...R....N....LLPL............EKKMKDSITAVQKLHKSMGKDTeagdlKNLSRNL.......LA..ASEALKEQA....AIVEQLQNQVESFDSK----eyy....................
L8JDA2_9GAMM/90-243                  .........................dvsfanfqplleeygri---------------------------------------........------...------..----HNTADQW........KRNIYPGV....IDLA.FDLSNY.....A.....S.....V.....HSDLIIPVLESLnemrn....tkdtseAEMWRD.FAIEQLKTL....N...E....M....ATDR............QNKVSDVVKQLNDFSTNLETEN.....AQLATLK.......DS..HSEFLDDDGsklkEKIKKLEADIQDLNEEY---dyn....................
A0A182K4B2_9DIPT/1-116               ....................................mseqaa---------------------------------------........------...------..-----------........------RL....QSHN.QEMVKC.....L.....S.....Q.....LRSQQTALEEKIt.............mQEKKKD.SLSKEMEKL....Q...Q....T....LEQL............ETSIADDTKMLNDCSKRLAETE.....NGYTKVV.......DT..LQLLLMSAK....EKVSTT--------------tstsikqddskns..........
A0A1L9RIA1_ASPWE/50-217              ........................yattfgfqisdlnkdvsa---------------------------------------........---E-L...DSIIGS..YGEIRTTTTEF........RDKTWPAV....VDLA.AQIRDYagnagG.....T.....L.....DSSYYKAILDWVkey........cttkDDSKKA.ELKANISAV....V...K....DqlasIDKL............STNVKSTKETLKEFDTKTQTQS.....AALNNHK.......RK..VMDLLGGSE....GRIAALRKQIKTNQDDLQK-d......................
Q6LH90_PHOPR/5-179                   ........................................ns--STQKVSKANENQTSQGLIIQNYSNSILEQGEVNFSED.......eKLKTYQ...SQINNS..IRLAKAHATRY........INVIQPSI....IQNI.SNIGNY.....Y.....N.....L.....HQVIATQLPENA...............---TKE.EWLEVLGAL....K...Q....E....AINY............EKTSRSTVILIQDLHSNLAVDS.....SSFSTTV.......DN..LNNVLNGDK....GVLSTLKNELGSIQGKISG-a......................
A0A182LQZ9_9DIPT/1-117               ....................................mteqaa---------------------------------------........------...------..-----------........------RL....QTHN.QEMVKC.....L.....N.....Q.....LRSQQTALEEKIa.............aQEKKKD.SLSKEMEKL....Q...R....T....LEQL............ETSIAEDTKALNDCSKRLTETE.....NGYAKVV.......DT..LQLLLMSAK....EKVNTTTPTSRSVH------sesskh.................
A0A1Y2M621_EPING/89-240              .............................lydvmkivlpriq---------------------------------------........------...------..-----QNTTRF.......rIDTLEPMI....L-LG.GKIANF.....S.....K.....F.....AGDYLKMLSNFInkmteh...pvnspqYNKEKK.GAATVLKAL....K...D....H....AEKV............QAECTKTVNELGAFKVLTGQDA.....SDLKSIQ.......ER..IHKVIPNED....AKN-----------------sviagliadakrlveaareqida
A0A233HNS4_9VIBR/12-189              ........qqttqsaflattvitaqchailntqftpptvkpd---------------------------------------........----WF...DDLSKK..LDSAKLVAKQW........IDDLGPQV....SASIpSSVINF.....D.....A.....T.....FQASIDAIHELYkadp......tasgkDNTTVQ.QASQIMTAL....S...S....Q....VSGI............EATVKGMNKELSDWGVKMQAAH.....DDLVNGA.......TN..IQKTIIDLQ....TDIESMNNAIDNNRAAIEK-l......................
A0A2B4SLM4_STYPI/8-182               .....................................slsnp-----AIKDKQVEVTKASTVIQTYVSIILQQPDLELDAL........------...PNLSAH..QKTARDHANNW........NDTILPLM....SKTD.ADIIDY.....A.....N.....K.....FDSFYNDLVTYAkd...........ikTPQSKK.NLIEVLKLL....G...T....T....IKQK............NANVQVVVKDLSTFHANLNTDY.....QNFHSDV.......NQ..AAVKIEGDS....GEIKALSDQLDAIHDAIKK-d......................
A0A0W7YA75_9BACI/47-226              .........................................s-ANEAKMRETLQKAGLFAKSMNAYSYMLIKNPDVNFEGIn.....inGYEDLP...GKIVQD..QKDARAHALTW........DTKVKKQL....IDTL.TGIIEY.....D.....T.....K.....FENYYDVIVYAI...............NANDGE.TLIEGITDL....R...E....E....IQEN............QKCAQQLIEALTELRDNIGKDV.....RAFGSNK.......EL..LQSILKNQG....AAVEDDQKRLNEVLESVNY-y......................
A0A0D3V886_9BACL/48-207              ......................kalaldnavslpdfgelytv---------------------------------------........------...------..NTSIKDHCTNW........NDTTYRGI....LDVA.HQIVNY.....S.....G.....R.....AKVYYAPLLELLpdi.........legDNEALE.KFQKICKKL....A...S....E....AKEF............GDHAGTLAEAVGKFATDTAADY.....TNLITVK.......VK..YDKLYGENS....QVVKDLRTEVDKLRKELE--qytdefedye.............
A0A1G6J6S1_9BACI/49-199              ....................dfeskaqeagkaglsaenqala---------------------------------------........------...---RQH..EKIVYEQAQQW........QDSLKGES....NRTR.DQVLSY.....D.....D.....T.....FNRMFDEIIDAL...............AADDED.GILERLDNM....Q...D....D....VTTH............KGAVTQFLDDLRTYKSDIGKNV.....SLMQADI.......DK..IENLMDGYR....ASLDKLYDKLSE--------dlddvvrs...............
A0A094E4U9_9PEZI/53-218              .....................gvtnleaslvpmvqnlldtyg---------------------------------------........------...------..--QIATHCKYF........KDTTYPSV....VHLA.DDVYTY.....A.....Q.....TaggtaDDSFYAAIISTYlqlvde...lakplpDPQKVA.TLQTSIKQL....I...A....NevgqIEQL............RTTATGVTSALRAFEGQTMQDQ.....QALSISQ.......TA..LTDKLTGEG....GDIPRLTQTIKNELD-----elaad..................
A0A094G668_9PEZI/53-218              .....................gvtnleaslvpmvqnlldtyg---------------------------------------........------...------..--QIATHCKYF........KDTTYPSV....VHLA.DDVYTY.....A.....Q.....TaggtaDDSFYAAIISTYlqlvde...lakplpDPQKVA.TLQTSIKQL....I...A....NevgqIEQL............RTTATGVTSALRAFEGQTMQDQ.....QALSISQ.......TA..LTDKLTGEG....GDIPRLTQTIKNELD-----elaad..................
#=GC SS_cons                         ........HHHHHHHHHHHHHHHHHHHHHHT-EE---CCHHC-----HHHHHHHHHHHHHHHHHHHHHHHHT------TT-.......GGGHHCH...HHHHHH..HHHHHHHHHHH........HHTHHHHH....HHHHHHHHHHH.....H.....H.....H.....CHCHHHCCHCCHHH-T......T--STT-HHHH.HHHHHHHHH....H...H....H....HHHH............HHHHHHHHHHHHHHHHHHHHHH.....HHHHHHH.......HH..HHHHCCCCC....CHHHHHHHHHHHHHHHHHH-HH.....................
#=GC seq_cons                        .........................................t..................................ph....................tpl.pt...pss+spuppa........hsshtPpl....lshs.sslhsY.....s.....s.....p.....hssahsslhphh...............sppsps.phtptlstL....p...s....p....lpph............pppsppshppLpsapsphspDp.....pshpsps.......sp..lpshlsups....uslspLppplpshpppIp..t......................
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