GenomeNet

Database: Pfam
Entry: Baculo_IE-1
LinkDB: Baculo_IE-1
Original site: Baculo_IE-1 
#=GF ID   Baculo_IE-1
#=GF AC   PF05290.12
#=GF DE   Baculovirus immediate-early protein (IE-0)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_7745 (release 7.7)
#=GF GA   33.10 33.10;
#=GF TC   33.30 86.30;
#=GF NC   32.70 33.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9188574
#=GF RT   A mechanism for negative gene regulation in Autographa
#=GF RT   californica multinucleocapsid nuclear polyhedrosis virus. 
#=GF RA   Leisy DJ, Rasmussen C, Owusu EO, Rohrmann GF; 
#=GF RL   J Virol 1997;71:5088-5094.
#=GF DR   INTERPRO; IPR007954;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The Autographa californica multinucleocapsid nuclear
#=GF CC   polyhedrosis virus (AcMNPV) ie-1 gene product (IE-1) is thought
#=GF CC   to play a central role in stimulating early viral transcription.
#=GF CC   IE-1 has been demonstrated to activate several early viral gene
#=GF CC   promoters and to negatively regulate the promoters of two other
#=GF CC   AcMNPV regulatory genes, ie-0 and ie-2. It is thought that that
#=GF CC   IE-1 negatively regulates the expression of certain genes by
#=GF CC   binding directly, or as part of a complex, to promoter regions
#=GF CC   containing a specific IE-1-binding motif (5'-ACBYGTAA-3') near
#=GF CC   their mRNA start sites [1].
#=GF SQ   44
#=GS Q287C0_NPVAS/99-239       AC Q287C0.1
#=GS A0A162GTL0_9BACU/111-252  AC A0A162GTL0.2
#=GS S5MJY8_9ABAC/118-259      AC S5MJY8.1
#=GS A0A2L0WTY8_9ABAC/118-252  AC A0A2L0WTY8.1
#=GS A0A0S3J1U0_9ABAC/108-242  AC A0A0S3J1U0.1
#=GS Q9IBQ9_9ABAC/99-239       AC Q9IBQ9.1
#=GS B7SW22_9ABAC/91-229       AC B7SW22.1
#=GS Q4KT70_9ABAC/161-301      AC Q4KT70.1
#=GS C3TWS2_9ABAC/135-276      AC C3TWS2.1
#=GS A0A068LMY5_9ABAC/96-236   AC A0A068LMY5.1
#=GS A0A2H4UZP3_9ABAC/95-238   AC A0A2H4UZP3.1
#=GS IE0_NPVLD/108-250         AC O36453.1
#=GS Q91BK7_NPVST/144-287      AC Q91BK7.1
#=GS Q0ILB1_NPVLS/143-285      AC Q0ILB1.1
#=GS A0EYR5_9ABAC/109-251      AC A0EYR5.1
#=GS Q7TLM7_NPVCF/108-244      AC Q7TLM7.1
#=GS M1JSC2_NPVSL/142-285      AC M1JSC2.1
#=GS IE0_NPVOP/112-245         AC O10369.1
#=GS IE0_NPVAC/129-261         AC P41710.1
#=GS Q2NNT1_NPVHC/105-239      AC Q2NNT1.1
#=GS Q80LS1_NPVAH/108-243      AC Q80LS1.1
#=GS A0A0A7KTK8_9ABAC/97-237   AC A0A0A7KTK8.1
#=GS A0A2K9VSJ6_9ABAC/108-247  AC A0A2K9VSJ6.1
#=GS A1YRH1_9ABAC/120-255      AC A1YRH1.1
#=GS A0A0E3Z8C5_9ABAC/136-271  AC A0A0E3Z8C5.1
#=GS Q0N487_9ABAC/128-269      AC Q0N487.1
#=GS A0A126FC27_9ABAC/133-272  AC A0A126FC27.1
#=GS Q8B9C1_NPVR1/126-261      AC Q8B9C1.1
#=GS A0A172WZ94_9ABAC/144-283  AC A0A172WZ94.1
#=GS W5VKA9_NPVBS/111-251      AC W5VKA9.1
#=GS A0A0M3WNB3_9ABAC/108-248  AC A0A0M3WNB3.1
#=GS Q91GD2_NPVEP/107-243      AC Q91GD2.1
#=GS Q1HH80_NPVAP/108-240      AC Q1HH80.1
#=GS A1YJD2_NPVSF/92-232       AC A1YJD2.1
#=GS B6D675_9ABAC/100-240      AC B6D675.1
#=GS B0FDN1_9ABAC/138-277      AC B0FDN1.1
#=GS A0A0B4ZUH4_9ABAC/168-308  AC A0A0B4ZUH4.1
#=GS Q77KA3_9ABAC/135-275      AC Q77KA3.1
#=GS V9XPQ8_9ABAC/110-244      AC V9XPQ8.1
#=GS B5X003_9ABAC/135-275      AC B5X003.1
#=GS L0CLT6_9ABAC/127-262      AC L0CLT6.1
#=GS A0A097P8V2_9ABAC/99-261   AC A0A097P8V2.1
#=GS I3XMH6_NPVMB/93-233       AC I3XMH6.1
#=GS D4N255_9ABAC/108-250      AC D4N255.1
Q287C0_NPVAS/99-239                  ..........................IEHLKSQPKFQYNMFIFLPYIRQLRIINDL.FAND.Y.CCTAIVKFNANALAALCEEGDK.YLHVIKLMKERMHLINVFTNP...KIYQCNICQETSSEPHFLKP.NECCGYSMCNLCYANLWKFCN..MYP.VCPVCKTSFKSSKKIVD--rd.....
A0A162GTL0_9BACU/111-252             .......................ind---MCCESKYVYNKFIFVPYLSQLKSMNSV.FLND.F.CCVDVAKNNLSIITQIMNNVNE.QLNTLKEIIVRANAIGVFAGT..lRVFRCNICNETSNYRKFLKT.NECCGYLMCFLCYANMWQFST..LYP.VCPICKTSFKKP-------islavkn
S5MJY8_9ABAC/118-259                 .......................vfk--LMKTMPKLRRNMYIFLPYYRQLRLILHY.FKDD.F.CCRNIINDVLMTLDCLTMESNE.RLEIVKTLYKQLQVMMVFTEP...VVYECNICHETSGEKHFLKQ.NECCGYNICNACYAKLWQHCK..LYP.VCPVCKTSFKSVSVVS---kny....
A0A2L0WTY8_9ABAC/118-252             ......................lekf----FEMRNNRNNVLVFYPYLKQLNGSAQV.LKKT.FvCCLVLIENMQTYINEVVSHCLL.CIQKLKLLQQTVEVMNLFAEK..tILYECDVCKEVSTDKRFLKP.KECCEFSICNACVVKLWKMAT..THA.KCPACRMSFK---------c......
A0A0S3J1U0_9ABAC/108-242             ................vksvetvsag-----------VNVIVLLPYLKQLQTALKM.LGDAfK.CCAKTINGLLLYVNDLLSHCLL.CADKIQAATRTLQVMNLFLDT..dTLYECDLCKEISTDQRFIKP.KECCQYTICNACCVTLWKTAS..THA.KCPACNTSFKSS-------.......
Q9IBQ9_9ABAC/99-239                  ..........................LEHLKSQPKFQYNMYIFMPYVKQIMVINDM.FKND.F.CCTAIVKTNSNALRELCERGEK.YMHVIKLMNERMQIINVFTNP...KVYQCNICQETSAEEHFLKP.NECCGYNLCYVCYVELWKHCS..LYP.VCPVCKTSFKNSKLERN--sa.....
B7SW22_9ABAC/91-229                  ..........................LEHLKSQPKYQYNMYIFIPYVKQIRIINDM.FKND.F.CCVATVKANDAALNELCERGEK.YMHVIKLMNERMQLINVFTNP...KVYQCNICQETSAEEHFLKP.NECCGYNVCYMCYVELWKHCS..LYP.VCPVCKTSFKTSKKD----rg.....
Q4KT70_9ABAC/161-301                 ..........................LQHVNRMSKFEYSMYVFMPYLKQIRKTIIL.FVND.F.CCKKLVENYLLTLDAMIADSLK.LLETIQMINKRVDVMNVFLDR...PVYRCNICEDTSLESRFLKP.NECCGYSICNMCYANLWKFCT..LYP.VCPVCKTSFKSSGSAAS--sl.....
C3TWS2_9ABAC/135-276                 .........................m-RKMCEQPIIIHNAFVLLPYCRQLKIILNK.FSND.Y.CCASLIESSFLKLNAIIADSLN.RLEAIKTLHDRVQIMLVFADD..kPIYECNICRNVSNEEYFLKP.DECCGYRICGMCYAKLWQHCK..LYP.VCPVCKTSFASSC------grstva.
A0A068LMY5_9ABAC/96-236              .........................v-RHLSEQSRYQHSMFIFLPYVRQLRQLNQH.FVHD.H.CCGVVVRSNAAALDAFVAAGEK.YLHVIRTMNERMHVINVFTEP...RIYQCNICQDASLQENFLKP.NECCGYNICNMCYANLWKFCN..MYP.VCPVCKTSFKSSKQIVE--nd.....
A0A2H4UZP3_9ABAC/95-238              ......................iiql----ASVTIFKNVAFVFVPYVKQIKITAQL.FQND.A.CCQTLVIKLINECNQLIEDCYKqYNDTVCRLQNRIDLTNILLDK...AKY-CNLCNEHSNLPKFLKTgKTCCSYSICNMCYSTLLERSIkdKKPaSCPACRKTYKIG-------dtddce.
IE0_NPVLD/108-250                    .........................l-RAMRAMSRFEHNVFVFLPYCKRLRALVEL.FRHD.Y.CCQSTVAGCARALDETIADAQR.HLLVVRSMSERAAVMLVFSDW..vRVYQCNICEDSSAEEQFLKP.NVCCGYRVCNACYAKLWEFCT.gAYP.VCPICKTGFKSSSSNKR--lq.....
Q91BK7_NPVST/144-287                 ....................iedlyd-----ASPVYRLNYFIFVPYVKRLLQIICM.FTND.V.CCKRSVRSTIARLETCLKRGNE.KLESVRRLNKTLNVMSVFLEQ...NVYECNICKDVSNDERFLKP.DECCGFRICNLCYANLWKFSNtpHNP.VCPVCKTSYRVEKYES---ssp....
Q0ILB1_NPVLS/143-285                 ..........................MENLYQIELYKLNYFVFIPYLKQLLAILNL.FVND.A.CCKKYTRIAKDILEVSLKRSQE.QLDCVQRITKTVQVMNVFLET...PLYECGICTEASTEATFLKP.NECCGFKICNVCYANMWKFSKsaVHP.VCPVCKTSYRSDNKPFS--qp.....
A0EYR5_9ABAC/109-251                 ....................iesmsn-----VDDQYRYCMFVFVPYAKQLLTILEC.FKND.Y.CCKNVVQQSLEYLQKLLQDSRQ.TFETLKTIHERIKTVNVFFDY..pKIYECNICQETSVERQFLKP.NVCCGFNICGMCYAQLWQHCN..LYP.VCPVCKTSFKSISTT----veik...
Q7TLM7_NPVCF/108-244                 ...............iecvksvetas---------AGHNVVVLLPYLKQLQVALKV.LSDAfA.CCAKVISGLQLYVQDLLSHCLL.CAEKIEAAGRTLQMINLFLDT..nSLYECDLCKEASTDARFLKP.KECCQYSLCNACCVILWKTAT..THA.KCPACSTSFKS--------.......
M1JSC2_NPVSL/142-285                 ....................iedlyd-----ASPVYRLNYFIFVPYVKRLLQIICM.FTND.V.CCKRSVRSTIARLETCLKRGNE.KLESVRRLNKTLCVMSVFLQQ...TVYECNICKDVSHDERFLKP.DECCGFRICNLCYANLWKFSNtpHNP.VCPVCKTSYRVEKYESS--ss.....
IE0_NPVOP/112-245                    .................ksveatsvg-----------INVIVLLPYLKQLQIALKM.LSDA.FaCCAKTIGGLQMYVQDLLSHCLL.YADRVEAAGRALQVMNLFLNSg.gPLYECDLCKEASADPRFLKP.KECCQYSLCYACCVALWKTAS..THA.KCPACSTSFKS--------.......
IE0_NPVAC/129-261                    ................iesaygvrdr-----------GNVIVFYPYLKQLRDALKL.IKNS.FaCCFKIINSMQMYVNELISNCLL.FIEKLETINKTVKVMNLFVDN..lVLYECNVCKEISTDERFLKP.KECCEYAICNACCVNMWKTAT..THA.KCPACRTSYK---------.......
Q2NNT1_NPVHC/105-239                 ....................vkkmdv------IHNGNVNVIVLLPYLKQLQAALAL.LHDAfA.CCSNTINGLQMYVQELVLHCLQ.CADKIETANRTLQVMSLFLDT..nVLYECDLCKEASTDRRFLKP.KECCQYALCNACCVTLWKTAN..THA.KCPACSTSFKS--------.......
Q80LS1_NPVAH/108-243                 .......................vve---IVNSPKYKNSQYIFIPYVKQLKLAIYY.FVND.Y.CCNKLVNEIIERLDLILNESNK.YLDYIRLLHERVQVMNVFRDE..iVLYTCNICHETSLEKSFLKP.NECCGYSICYSCYANLWKFCD..LYP.VCPVCKHGFKKSN------.......
A0A0A7KTK8_9ABAC/97-237              ..........................LEHINSQPKYQYNIYVFLPYVKQIRLINNM.FLED.F.CCSSIVKTNATAIKNLCDQGEK.YLQVIKLMNERMHLINVFTEP...KVYQCNICQETSAEEHFLKP.NECCGYSMCNMCYANLWKFCN..MYP.VCPVCKTSFKTSKRML---deq....
A0A2K9VSJ6_9ABAC/108-247             ..........................LHHINSQPKYQYNMFIFLPYVKQLRMINSR.FESD.Y.CCAKIVKANALALSTLVAHADK.YLSAIRAMNERMHLINVFVEP...KLYQCNICQESSVEEHFLKP.DECCGYSICCMCYANLWKFSN..MYP.VCPVCKTSFKSSSKK----ive....
A1YRH1_9ABAC/120-255                 ..............ikeiesaygvrd----------RSNVIIFYPYLKQLRDALKL.IKNS.FvCCFKAINSMQMYVNELISNCLL.FIEKLETINKTVKVMNLFIDD..vVLYECNVCKEVSTDERFLKP.KDCCEYAICNACCVILWKTAA..THA.KCPACRTSYK---------.......
A0A0E3Z8C5_9ABAC/136-271             ........................ll--EINSTPAYQNNMYIFAPYCKQLLKISSM.FLND.Y.CCNAVVERSVAALNTIVADSRR.YLDALALLQRRVNAMCVFLER...DLYRCNICHTTSAEEHFLIK.NTCCGYQMCGVCYAKLWQFCK..LYP.VCPACKVVFAKD-------td.....
Q0N487_9ABAC/128-269                 ........................ll--FVVQQEMYVHNVYIFLPYLRQLKQMLSN.FVND.Y.CCSSVVQKCIQSVDSLMQRSTK.YLEAIKFISDRLLVMNVFDDS..iKIYQCNICQNTSVEEHFLKP.DTCCGYRICFACYSQLWQYCN..VYP.VCPVCKTSFKKSNANNKK-l......
A0A126FC27_9ABAC/133-272             ..............kqlelsfdaner-----------GNILIFYPYLKQLCVTIDM.LKKSfK.CCTNLLNNLGVYINNIITNCLL.YIEKVKAINKSIQVINVFVDD..sAIYECNICKEISTDERFLKP.KECCEFVMCNSCCVQLWKMAN..THA.KCPACNTSFKSIK------ik.....
Q8B9C1_NPVR1/126-261                 .............ikeiesaygvrdr-----------GNVIVFYPYLKQLRDALKL.IKNS.FaCCFKIINSMQMYVNELISNCLL.FIEKLETINKTVKVMNLFVDN..lVLYECNVCKEISTDERFLKP.KECCEYAICNACCVTMWKTAT..THA.KCPACRTSYK---------.......
A0A172WZ94_9ABAC/144-283             ...............lecsfdtvhhr----------RGNVLIFYPYLKQLRELLKL.LKKT.FvCCTKTIDNMQMYVSDTILHCLL.FVEKLELMNKTIKVMNLFADNdttTLYECNICKEVSNDKRFIKP.KECCEFAICNACCVTLWKTAT..THA.KCPACRTSFKS--------ln.....
W5VKA9_NPVBS/111-251                 .........................i-KLMSTMPNFKYCSYIFLPYCKQLRVYNAY.FTND.Y.CCEKTLNATRHALEELTASGNE.SLAVVKRLRERLDVMIVFTDP...VLYECYICRNASTEKNFLKP.NECCGFNICGMCYAQLWQHCT..RYP.VCPVCKTSFKTFSNNS---dpk....
A0A0M3WNB3_9ABAC/108-248             ..........................LQHIALMPEYQYNMFIFLPYMKQLHKTISL.FQND.Y.CCSKLVQQCIQSLNVHIRDAEK.ILSLVNNMQNRLNIMCIFDSK...PFYHCNICQESSLDVGFLKA.NTCCGYSMCNACYAKLWQYSS..LFP.VCPVCKTSFKNSNSGNS--sk.....
Q91GD2_NPVEP/107-243                 .............vecvksvekasvg-----------VDIIVLLPYLKQLQLILKM.LNDA.FvCCEKSLGRLQMYVNELLSHCLL.CAEKIEAASRTLQVMSLFVNT..gTLYECNLCKEISTDKRFLKP.KECCQYSICNACCVTLWKTAS..THA.KCPACNTSFKS--------.......
Q1HH80_NPVAP/108-240                 ...............cvksveaasag-----------VNVVVLLPYLKQLQIVLKMlFDAF.A.CCSKTINGLQMYVHDLLSHCLL.CADKIEAANRALQVINLFLDS...PLYECDLCKEASADKRFLTR.KDCCAYALCNACCVALWKASV..THA.KCPACSTSFK---------.......
A1YJD2_NPVSF/92-232                  ..........................IQNLNTQPKFQYNMYIFIPYIKQIRVINNM.FVND.F.CCSAIVKSNSVTLNDLYDRSEK.YLHIIKLMNERMQLINVFTDP...KIYQCNICQESSAEEHFLKP.NECCGYNVCYICYAQLWKHSS..LYP.VCPACKTSFKTPTAAKQQ-i......
B6D675_9ABAC/100-240                 ..........................LEHLNSQPKFQYNMYVFLPYVKQIRLINDM.FVKD.F.CCSTIVKSNATALNNLCEQGEK.YLQVIKLMNERMHLINVFTEP...KVYQCNICQETSAEAHFLKP.NECCGYSMCNMCYANLWKFCN..MYP.VCPVCKTSFKSSKRMLDQ-q......
B0FDN1_9ABAC/138-277                 ........................vl-KMMSVLPRFRYNMYIFLPYCRQLKLILAC.FVND.Y.CCKTVVRAQIDALNEIIDNATQ.LLRLVKTLNNRLKVMMVFAEP...KLYECHICRETSMEQHFLKP.NECCGFNICGLCYAQLWQHCK..LYP.VCPVCKTSFKTVS------dspl...
A0A0B4ZUH4_9ABAC/168-308             ..........................LQHVKRMSKFEYSMYVFMPYLKRIRKIIIL.FVND.F.CCKKLVKNYLISLDMMIENSAK.LLETIQMINKRVDVMNVFLDR...PVYRCNICDDTSLESRFLKP.NECCGYSICNICYANLWKFCT..LYP.VCPVCKTSFKSSGSAAS--sl.....
Q77KA3_9ABAC/135-275                 ..........................MNFSDDEVNYVKQKFIFLPYLKYLNKILKL.FQYD.K.CCAKLTKQLQAQLNTLLTQSAD.SCKHIHAINRQSQVLTVFLEN...PLYECNICRDTFNDERHIKP.NECCGYKICNLCYANLWKYST..VFP.TCPVCKTSFKSSSVSSFK-q......
V9XPQ8_9ABAC/110-244                 ..................cvksveta--------SASHNVIVLLPYLKQMQVALKV.LSNA.FaCCTKVISGLQLYVQDMLSHCLL.CAEKIEAASRTLQVMNLFLDT..sLLYECDLCKEASTDARFLKP.KECCQYSLCNACCVILWKTAS..THA.KCPACSTSFKS--------.......
B5X003_9ABAC/135-275                 ..........................MNFSDDEVNYVKQKFIFLPYLKYLNKILKL.FQYD.K.CCAKLTKQLQAQLNTLLTQSAD.SCKHIHAINRQSQVLTVFLEN...PLYECNICRDTFNDERHIKP.NECCGYKICNLCYANLWKYST..VFP.TCPVCKTSFKSSSVSSFK-q......
L0CLT6_9ABAC/127-262                 ................iesayapqdr-----------GNLIIFYPYLKQLREGLKL.IQNS.FvCCSKTINSMQMYINELISHCLL.FIEKLETINKTVKVMNLFMDN..lILYECNVCKEVSTDERFLKP.KECCEYAVCNACCVIMWKTAT..NHA.KCPACRTSYKS--------ln.....
A0A097P8V2_9ABAC/99-261              lsiddgqclhhliqtvgnvikvivlm----SIMPQFQFCLYIFAPYCRQLTIVLKY.FEND.F.CCKQTVEKSLQSIAKIIEQGHH.QMETVKRFQKKLDAMLVFSEP...QIYECNICQETSREKHFLKP.NECCGFSICGLCYAQLWQHCT..RYP.VCPVCKTSFKTAKHA----ydtk...
I3XMH6_NPVMB/93-233                  .........................i-GHLNNQPKFQYNMYIFLPYVRQLRQINTL.FLND.Y.CCSKIVKSNGAALDTLIAHCDK.YLHVIASMNERMQLINVFTEP...KLYQCNICQDTSVEEHFLKP.NECCGYNICNMCYANLWKFCN..LYP.QCPVCKTSFKGSKQVVEQ-e......
D4N255_9ABAC/108-250                 .........................l-RIMRAAPRFEHNIFIFLPYCKRLRALVEL.FRHD.Y.CCQSTVAGCARALDETIADARR.YLLVVKSMSERAAVMLVFSDA..lRVYQCDICHDSSAEEQFLKP.NVCCGYRVCNACYAKLWEFCT.gAYP.VCPICKTSFKSSSSKKR--lq.....
#=GC seq_cons                        ...............................t.staphNhalFlPYlKQLphhlph.FpsD.a.CCppllpshthtlspllscutc.hlctlcthscplpVMNVFh-s...hlYcCNICcEsSs-c+FLKP.sECCGYslCNhCYupLWKass..haP.sCPlCKTSFKost.............
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