GenomeNet

Database: Pfam
Entry: Bd3614-deam
LinkDB: Bd3614-deam
Original site: Bd3614-deam 
#=GF ID   Bd3614-deam
#=GF AC   PF14439.8
#=GF DE   Bd3614-like deaminase
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF SE   Manual
#=GF GA   38.50 38.50;
#=GF TC   39.10 38.70;
#=GF NC   37.20 37.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0109
#=GF RN   [1]
#=GF RM   21890906
#=GF RT   Evolution of the deaminase fold and multiple origins of
#=GF RT   eukaryotic editing and mutagenic nucleic acid deaminases from
#=GF RT   bacterial toxin systems.
#=GF RA   Iyer LM, Zhang D, Rogozin IB, Aravind L;
#=GF RL   Nucleic Acids Res. 2011; [Epub ahead of print]
#=GF DR   INTERPRO; IPR025853;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A member of the nucleic acid/nucleotide deaminase superfamily 
#=GF CC   prototyped by Bdellovibrio Bd3614 [1]. They are typified by a 
#=GF CC   distinct N-terminal globular domain. The Bdellovibrio version
#=GF CC   occurs in a predicted operon with a 23S rRNA G2445-modifying 
#=GF CC   methylase suggesting that it might be involved in RNA editing
#=GF CC   [1].
#=GF SQ   14
#=GS A0A540WQT4_9DELT/201-307  AC A0A540WQT4.1
#=GS K8ECS5_9CHLO/323-376      AC K8ECS5.1
#=GS Q6MHD6_BDEBA/164-275      AC Q6MHD6.1
#=GS A0A514X0G6_9PROT/166-276  AC A0A514X0G6.1
#=GS A4S9Y1_OSTLU/127-236      AC A4S9Y1.1
#=GS A0A545UC87_9GAMM/225-338  AC A0A545UC87.1
#=GS A0A150WQ10_BDEBC/162-271  AC A0A150WQ10.1
#=GS A0A4P2VPN2_9PROT/160-271  AC A0A4P2VPN2.1
#=GS C1MW10_MICPC/272-409      AC C1MW10.1
#=GS K8ECS5_9CHLO/371-433      AC K8ECS5.1
#=GS A0A096P9Z0_OSTTA/247-360  AC A0A096P9Z0.1
#=GS C1EBX0_MICCC/256-391      AC C1EBX0.1
#=GS A0A1L4D3C2_9PROT/160-271  AC A0A1L4D3C2.1
#=GS A0A254Q8I1_9PROT/165-275  AC A0A254Q8I1.1
A0A540WQT4_9DELT/201-307             ....aqegk------GQSVGAVLVDGT.GKILSWSVN.T..A.YDNACFHAEVNLLHAYLGR......H---..-------------------QQLPDGfAILYTTLQPCHMCAGLIAGLIEQ-GH--ELQVVYGEHDTHYSGGRTVLDEK--------naql....................
K8ECS5_9CHLO/323-376                 ....erfer----ASHRNVVAALRDDAtGKIISLAKN.T..N.GGNKILHAEMNLLLNHEK-......----..-------------------------.-----------------------------------------------------------tgtkk...................
Q6MHD6_BDEBA/164-275                 ........s-VLHDYDRDIAAFLLNDQ.GQLLSYGVN.S..N.SKNKTLHAEVNLVQRLHRE......T---..------------------GRPIPAG.AVLYSTHKPCKMCAGMIYHWCEDPSQ---LKVYYSVEEKGGLSRQTVLDQHGLNHHISK........................
A0A514X0G6_9PROT/166-276             ........d-VLHDYDRDIAALLVSRD.GQLLGFGLN.S..N.SKNKTLHAEVNLLQRYFKE......H---..------------------GHGIPED.AILYSTHKPCKMCAGMIYQASGRSQ---RLQVIYLHEEDGSLSRATILDQLKLS-----kqlp....................
A4S9Y1_OSTLU/127-236                 .........RSRRGRDRKVFAALHSPTrGGVYAVAAN.T..N.GGNAVLHAEMNLLFPADDA......RA--..------------------RRLIEPD.TTLLVTLQCCRMCAARAVELGV-------RRAAYLREDPGPLASRTALAALARESRFD-l.......................
A0A545UC87_9GAMM/225-338             ....ehsgh--------EIASLLVSPD.GRVLSWGLN.N..S.HCNPTFHAEVSMLQRYYYY......HS--..---------QCGGCENCDKGQIPMG.SIIYTTLKSCWMCAGMAHDYCN--GR--QVTVIYNQNDDGRHAHNTPLD----------lpmrsd..................
A0A150WQ10_BDEBC/162-271             ........k-ILHDYHRDIAAVLMGPE.GDCLSYGLN.S..N.ALNKTLHAEVNLVHRLFKD......R---..------------------GVKIPKG.SVLYSTHKPCKMCAGIIHDWSEDPRH---VQVYYHHHEDGGLSRATALDKIGMQN----ql......................
A0A4P2VPN2_9PROT/160-271             .......ke--KYDSCRQVACLLIDSN.RNILSFGLN.E..N.SKNKTLHAEINMIQKFYNQ......F---..------------------RQAIPKG.SSIYTTLKPCKMCAGMIWHCAENISD---FKVYFLNDDPGSMAKSTVLNCNSIERL---raa.....................
C1MW10_MICPC/272-409                 .........KARWRRDRRVVAMVVDRD.GVLVDAAVN.T..N.AENAMLHAEFNLLMPWLMR......LDGDgdGDGDGDGDGDGDGDGEAARKSLPPG.ARLFVSLQCCAMCAALVCAASDARGGEVLTDVVYGEEDPGALARDTELRRRGWERKRDE........................
K8ECS5_9CHLO/371-433                 ....ktgtk------------------.---------.-..-.-------------------......----..-------------------------.KTLLVTLQCCRMCAALSQRYAN-----ELSEVVYLRADTGPLAKMTALQ----------iceegklrerkhae..........
A0A096P9Z0_OSTTA/247-360             ........r-SRRRTNRAVFAALHSPS.RGIYRVAAN.T..N.GANKALHAEMNLLLNLRTT......SA--..--------------HAQTPDALDPD.TTLLITLQCCEMCAALACEFDA------VVAAEYFRADDGPLARRTALQI---------dphrreraf...............
C1EBX0_MICCC/256-391                 .........TQLWERDRGVVAALVSPR.GEVTDAARN.V..N.ADNKCLHAEWNLLAPTLWG......EWVL..SPTEDDEIANRPGAGPEEAGPLEEG.TRVLVTLQCCKMCAALVCAAADRPGRRGPIEVVYLNPDDGSLARDTQLRRRGWESRHA-a.......................
A0A1L4D3C2_9PROT/160-271             .......ne--LYQSNRKIACILVSEE.SKILAVGLN.E..N.SKNKTQHAEVNLIQSFYQT......F---..------------------KKPLPKN.TTLYTTRKPCKMCAGMIWTCTEDI---KLLKVFFLHDDPGSMAKYTVLNRGTLERKRA-a.......................
A0A254Q8I1_9PROT/165-275             ........e-VLHDYDREIAALLIAPD.GKVLSYGVN.S..N.SINKTLHAEVNLVQRYFRE......N---..------------------GRKIPPG.SVLYSTHKPCKMCAGMIYEWSENPDQ---LKVYYSVEESGGMSKQTVLDRYGLNQRI--n.......................
#=GC seq_cons                        ........c..hhp.sRplsAhLlsss.GplluhulN.o..N.utNKsLHAEhNLltphhpp......p.......................tp.lP.s.shLasThpsC+MCAuhlhphspt.t....lpVhYhpcDsGshu+pTsLsphthp.....t.......................
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