GenomeNet

Database: Pfam
Entry: CCDC106
LinkDB: CCDC106
Original site: CCDC106 
#=GF ID   CCDC106
#=GF AC   PF15794.5
#=GF DE   Coiled-coil domain-containing protein 106
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q9BWC9
#=GF GA   30.20 30.20;
#=GF TC   30.30 30.30;
#=GF NC   29.70 30.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16169070
#=GF RT   A human protein-protein interaction network: a resource for
#=GF RT   annotating the proteome.
#=GF RA   Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H,
#=GF RA   Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J,
#=GF RA   Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksoz E,
#=GF RA   Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker
#=GF RA   EE;
#=GF RL   Cell. 2005;122:957-968.
#=GF RN   [2]
#=GF RM   20159018
#=GF RT   Identification and characterization of the novel protein CCDC106
#=GF RT   that interacts with p53 and promotes its degradation.
#=GF RA   Zhou J, Qiao X, Xiao L, Sun W, Wang L, Li H, Wu Y, Ding X, Hu X,
#=GF RA   Zhou C, Zhang J;
#=GF RL   FEBS Lett. 2010;584:1085-1090.
#=GF DR   INTERPRO; IPR031591;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   CCDC106, coiled-coil domain-containing protein 106, is a family
#=GF CC   of eukaryote proteins. Yeast two-hybrid screening has identified
#=GF CC   CCDC106 as a p53-interacting partner [1]. CCDC106 is a negative
#=GF CC   regulator of p53 and may be involved in tumourigenesis in some
#=GF CC   cancers by promoting the degradation of p53 protein and
#=GF CC   inhibiting its transactivity [2].
#=GF SQ   190
#=GS G3P8X1_GASAC/57-273       AC G3P8X1.1
#=GS A0A1U8D6E2_ALLSI/52-241   AC A0A1U8D6E2.1
#=GS A0A0P7XKP7_9TELE/94-323   AC A0A0P7XKP7.1
#=GS W5LIG5_ASTMX/63-162       AC W5LIG5.1
#=GS A0A2I2YTW7_GORGO/55-276   AC A0A2I2YTW7.1
#=GS G1LAY9_AILME/182-365      AC G1LAY9.1
#=GS K7E861_ORNAN/7-65         AC K7E861.1
#=GS F1RA94_DANRE/3-168        AC F1RA94.1
#=GS H2SP95_TAKRU/160-313      AC H2SP95.1
#=GS G3P8Y1_GASAC/66-181       AC G3P8Y1.1
#=GS A0A0N4SUE2_DANRE/67-266   AC A0A0N4SUE2.1
#=GS A0A2K5IWB8_COLAP/20-241   AC A0A2K5IWB8.1
#=GS G7NNV3_MACMU/55-276       AC G7NNV3.1
#=GS Q1LUD6_DANRE/76-193       AC Q1LUD6.1
#=GS A0A1U8CI38_MESAU/143-209  AC A0A1U8CI38.1
#=GS W5U8A3_ICTPU/133-328      AC W5U8A3.1
#=GS A0A2I4BK43_9TELE/71-167   AC A0A2I4BK43.1
#=GS H2MW02_ORYLA/1-124        AC H2MW02.1
#=GS I3JJ56_ORENI/89-357       AC I3JJ56.1
#=GS H3CRP9_TETNG/186-378      AC H3CRP9.1
#=GS H2P089_PONAB/55-276       AC H2P089.1
#=GS E2R0G1_CANLF/56-277       AC E2R0G1.2
#=GS CC106_BOVIN/53-274        AC Q1LZ89.1
#=GS L5LCE4_MYODS/31-138       AC L5LCE4.1
#=GS A0A091E1M5_FUKDA/180-401  AC A0A091E1M5.1
#=GS E9QPN6_MOUSE/117-337      AC E9QPN6.1
#=GS M4AIC6_XIPMA/151-329      AC M4AIC6.1
#=GS U3I2W5_ANAPL/1-40         AC U3I2W5.1
#=GS G3P451_GASAC/120-299      AC G3P451.1
#=GS M4AC00_XIPMA/219-394      AC M4AC00.1
#=GS H2SP96_TAKRU/57-280       AC H2SP96.1
#=GS H2SP95_TAKRU/58-136       AC H2SP95.1
#=GS A0A1S3MI67_SALSA/450-678  AC A0A1S3MI67.1
#=GS H2M7M4_ORYLA/244-384      AC H2M7M4.1
#=GS CC106_MOUSE/55-275        AC Q3ULM0.1
#=GS H0UT87_CAVPO/56-185       AC H0UT87.2
#=GS M3WF78_FELCA/56-277       AC M3WF78.2
#=GS Q1LUD6_DANRE/171-353      AC Q1LUD6.1
#=GS G1LAY9_AILME/44-116       AC G1LAY9.1
#=GS A0A2K5M2U4_CERAT/20-241   AC A0A2K5M2U4.1
#=GS A0A087XMQ5_POEFO/104-280  AC A0A087XMQ5.2
#=GS H9H6N1_MONDO/57-277       AC H9H6N1.1
#=GS G3P8X5_GASAC/57-155       AC G3P8X5.1
#=GS A0A286Y8H7_DANRE/437-550  AC A0A286Y8H7.1
#=GS F1RAC3_DANRE/436-549      AC F1RAC3.1
#=GS A0A0F8ANY5_LARCR/131-227  AC A0A0F8ANY5.1
#=GS A0A2I4AZE4_9TELE/81-310   AC A0A2I4AZE4.1
#=GS A0A0R4IQP1_DANRE/153-340  AC A0A0R4IQP1.1
#=GS A0A087XPB0_POEFO/14-249   AC A0A087XPB0.1
#=GS I3K4R8_ORENI/71-180       AC I3K4R8.1
#=GS F1QC35_DANRE/4-130        AC F1QC35.1
#=GS M4AC00_XIPMA/71-168       AC M4AC00.1
#=GS A0A286ZWQ5_PIG/56-277     AC A0A286ZWQ5.1
#=GS H9GME2_ANOCA/71-281       AC H9GME2.2
#=GS A0A0R4ICJ2_DANRE/72-226   AC A0A0R4ICJ2.1
#=GS G3P451_GASAC/31-133       AC G3P451.1
#=GS H3AFM0_LATCH/1-101        AC H3AFM0.1
#=GS I3K5V8_ORENI/13-238       AC I3K5V8.1
#=GS Q1LUD5_DANRE/58-185       AC Q1LUD5.1
#=GS A0A2I3RLM6_PANTR/47-268   AC A0A2I3RLM6.1
#=GS Q5EB04_DANRE/63-163       AC Q5EB04.1
#=GS A0A0F8AEI7_LARCR/256-398  AC A0A0F8AEI7.1
#=GS A0A1L8FGN5_XENLA/55-274   AC A0A1L8FGN5.1
#=GS A0A2I3HHB6_NOMLE/20-241   AC A0A2I3HHB6.1
#=GS E9QE99_DANRE/234-449      AC E9QE99.1
#=GS A0A1U8DI13_ALLSI/56-241   AC A0A1U8DI13.1
#=GS G3VFQ8_SARHA/57-277       AC G3VFQ8.1
#=GS A0A1U8D6E1_ALLSI/56-245   AC A0A1U8D6E1.1
#=GS A0A1A6GKP9_NEOLE/170-296  AC A0A1A6GKP9.1
#=GS H2QH75_PANTR/55-276       AC H2QH75.1
#=GS A0A0A0MUL9_PAPAN/55-276   AC A0A0A0MUL9.1
#=GS A0A2I4ALP3_9TELE/65-281   AC A0A2I4ALP3.1
#=GS A0A1S3M394_SALSA/137-329  AC A0A1S3M394.1
#=GS A0A2I3M9V6_PAPAN/20-241   AC A0A2I3M9V6.1
#=GS A0A0F8AEI7_LARCR/69-164   AC A0A0F8AEI7.1
#=GS A0A087XYJ3_POEFO/183-368  AC A0A087XYJ3.2
#=GS A0A0G2KLC0_DANRE/1-178    AC A0A0G2KLC0.1
#=GS S7NJX5_MYOBR/46-148       AC S7NJX5.1
#=GS A0A2D0SN53_ICTPU/336-561  AC A0A2D0SN53.1
#=GS H2TIT7_TAKRU/1-228        AC H2TIT7.1
#=GS A0A1S3Q934_SALSA/83-315   AC A0A1S3Q934.1
#=GS G7PZ00_MACFA/55-192       AC G7PZ00.1
#=GS F7EH53_XENTR/55-274       AC F7EH53.1
#=GS H3CJE2_TETNG/8-85         AC H3CJE2.1
#=GS A0A0D9S616_CHLSB/55-276   AC A0A0D9S616.1
#=GS B5X442_SALSA/71-175       AC B5X442.1
#=GS A0A140LGL1_DANRE/17-183   AC A0A140LGL1.1
#=GS A0A140LH77_DANRE/63-157   AC A0A140LH77.1
#=GS A0A2I4CJY3_9TELE/179-358  AC A0A2I4CJY3.1
#=GS H2T1A1_TAKRU/12-228       AC H2T1A1.1
#=GS A0A2K5M2V5_CERAT/55-276   AC A0A2K5M2V5.1
#=GS H3AFM1_LATCH/3-166        AC H3AFM1.1
#=GS A0A2D0RG94_ICTPU/230-377  AC A0A2D0RG94.1
#=GS L5KF71_PTEAL/56-298       AC L5KF71.1
#=GS I3K3F3_ORENI/7-216        AC I3K3F3.1
#=GS B8JI21_DANRE/67-230       AC B8JI21.1
#=GS A0A151MGJ0_ALLMI/52-233   AC A0A151MGJ0.1
#=GS F7IHD1_CALJA/55-276       AC F7IHD1.1
#=GS V8PET9_OPHHA/76-293       AC V8PET9.1
#=GS K7EMI9_HUMAN/20-241       AC K7EMI9.1
#=GS A0A1S3N371_SALSA/71-186   AC A0A1S3N371.1
#=GS A0A1S3N371_SALSA/239-391  AC A0A1S3N371.1
#=GS A0A140LIV9_MOUSE/3-65     AC A0A140LIV9.1
#=GS A0A1S3RYE2_SALSA/216-393  AC A0A1S3RYE2.1
#=GS W5LL15_ASTMX/56-274       AC W5LL15.1
#=GS A0A2K5IWB3_COLAP/55-276   AC A0A2K5IWB3.1
#=GS I3K1U1_ORENI/1-204        AC I3K1U1.1
#=GS A0A0R4IQP1_DANRE/58-190   AC A0A0R4IQP1.1
#=GS A0A140LIX8_MOUSE/55-109   AC A0A140LIX8.1
#=GS A0A1S3WRP0_ERIEU/55-272   AC A0A1S3WRP0.1
#=GS H0WVU5_OTOGA/56-277       AC H0WVU5.1
#=GS I3MQK5_ICTTR/56-275       AC I3MQK5.2
#=GS H3CRP9_TETNG/61-160       AC H3CRP9.1
#=GS G3TMP8_LOXAF/56-275       AC G3TMP8.1
#=GS L9KUA1_TUPCH/46-267       AC L9KUA1.1
#=GS A0A1S3RYE2_SALSA/71-170   AC A0A1S3RYE2.1
#=GS Q5EB04_DANRE/192-378      AC Q5EB04.1
#=GS A0A087XYJ3_POEFO/72-169   AC A0A087XYJ3.2
#=GS A0A1U7R6L1_MESAU/2-167    AC A0A1U7R6L1.1
#=GS A0A2I3HFV7_NOMLE/55-276   AC A0A2I3HFV7.1
#=GS K7EMP7_HUMAN/55-172       AC K7EMP7.1
#=GS H3AGC2_LATCH/55-268       AC H3AGC2.1
#=GS W5KQ74_ASTMX/66-200       AC W5KQ74.1
#=GS I3K0S3_ORENI/1-215        AC I3K0S3.1
#=GS A0A0F8CLD8_LARCR/20-222   AC A0A0F8CLD8.1
#=GS H2M3P9_ORYLA/40-153       AC H2M3P9.1
#=GS M3Y7B6_MUSPF/189-368      AC M3Y7B6.1
#=GS M3Y7B6_MUSPF/44-122       AC M3Y7B6.1
#=GS D4AAV8_RAT/114-335        AC D4AAV8.2
#=GS A0A0G2L3D6_DANRE/11-226   AC A0A0G2L3D6.1
#=GS M4AIC6_XIPMA/55-142       AC M4AIC6.1
#=GS G5BVY2_HETGA/98-319       AC G5BVY2.1
#=GS A0A2I2Z4C8_GORGO/20-241   AC A0A2I2Z4C8.1
#=GS F1Q991_DANRE/198-237      AC F1Q991.2
#=GS A0A1U8DGL1_ALLSI/56-275   AC A0A1U8DGL1.1
#=GS A0A1S3LU78_SALSA/23-161   AC A0A1S3LU78.1
#=GS A0A1U7SZW5_TARSY/56-276   AC A0A1U7SZW5.1
#=GS A0A286XTQ6_CAVPO/1-66     AC A0A286XTQ6.1
#=GS H2T1A2_TAKRU/8-126        AC H2T1A2.1
#=GS H2SP97_TAKRU/209-370      AC H2SP97.1
#=GS I3K4R8_ORENI/249-401      AC I3K4R8.1
#=GS A0A1S3M394_SALSA/57-135   AC A0A1S3M394.1
#=GS I3J4U8_ORENI/1-175        AC I3J4U8.1
#=GS G3P462_GASAC/63-174       AC G3P462.1
#=GS A0A0F8AGQ1_LARCR/50-262   AC A0A0F8AGQ1.1
#=GS A0A0G2L4Z1_DANRE/1-202    AC A0A0G2L4Z1.1
#=GS A0A096LTA3_POEFO/88-199   AC A0A096LTA3.1
#=GS G3RHZ6_GORGO/55-276       AC G3RHZ6.2
#=GS CC106_HUMAN/55-276        AC Q9BWC9.1
#=GS I3K5W0_ORENI/56-261       AC I3K5W0.1
#=GS S9XEE2_CAMFR/56-261       AC S9XEE2.1
#=GS I3K1U2_ORENI/1-204        AC I3K1U2.1
#=GS H2T1A2_TAKRU/133-322      AC H2T1A2.1
#=GS X1WFI5_DANRE/40-234       AC X1WFI5.1
#=GS A0A1L8FMT4_XENLA/404-623  AC A0A1L8FMT4.1
#=GS W5NSK7_SHEEP/120-341      AC W5NSK7.1
#=GS H3CJE2_TETNG/136-322      AC H3CJE2.1
#=GS A0A2I4CJY3_9TELE/83-157   AC A0A2I4CJY3.1
#=GS A0A2D0RG94_ICTPU/65-168   AC A0A2D0RG94.1
#=GS G3P462_GASAC/167-345      AC G3P462.1
#=GS F6RJW0_ORNAN/56-105       AC F6RJW0.1
#=GS A0A151MG69_ALLMI/56-237   AC A0A151MG69.1
#=GS I3K5V9_ORENI/5-231        AC I3K5V9.1
#=GS G3P8Y1_GASAC/173-377      AC G3P8Y1.1
#=GS W5MM13_LEPOC/1-223        AC W5MM13.1
#=GS M7ATU1_CHEMY/1-50         AC M7ATU1.1
#=GS A0A2I3SHL8_PANTR/20-241   AC A0A2I3SHL8.1
#=GS M3XI21_LATCH/69-266       AC M3XI21.1
#=GS A0A2I4BK43_9TELE/264-398  AC A0A2I4BK43.1
#=GS F1QJT8_DANRE/158-270      AC F1QJT8.1
#=GS W5KQ74_ASTMX/220-389      AC W5KQ74.1
#=GS A0A087XMQ5_POEFO/3-85     AC A0A087XMQ5.2
#=GS H2T1A0_TAKRU/55-273       AC H2T1A0.1
#=GS A0A0F8BK85_LARCR/82-312   AC A0A0F8BK85.1
#=GS A0A1U8CSL4_MESAU/74-184   AC A0A1U8CSL4.1
#=GS W5U8A3_ICTPU/58-160       AC W5U8A3.1
#=GS B5X442_SALSA/239-393      AC B5X442.1
#=GS H3C8M9_TETNG/6-179        AC H3C8M9.1
#=GS A0A286XTF3_CAVPO/154-375  AC A0A286XTF3.1
#=GS W5LIG5_ASTMX/213-383      AC W5LIG5.1
#=GS H2LN76_ORYLA/17-244       AC H2LN76.1
#=GS A0A0P7UEN8_9TELE/84-308   AC A0A0P7UEN8.1
#=GS H2M2I7_ORYLA/40-142       AC H2M2I7.1
#=GS S7NJX5_MYOBR/1-48         AC S7NJX5.1
#=GS E7FFX2_DANRE/437-570      AC E7FFX2.2
#=GS M7ATU1_CHEMY/45-148       AC M7ATU1.1
#=GS F7AW45_HORSE/54-275       AC F7AW45.1
#=GS H2SP97_TAKRU/61-156       AC H2SP97.1
#=GS A0A1S3GMF5_DIPOR/56-278   AC A0A1S3GMF5.1
#=GS H2M7M4_ORYLA/65-163       AC H2M7M4.1
G3P8X1_GASAC/57-273                  .........................................................................y-MVITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................G.--.-QEQKQQKSESQH.F..PSPSGSSGNG..NSATRSS.M-...SEMSGH.SN.IGPGT.INGNRHQF-...........KRRRIFRAP-.-RER..QR.V.....KDAAGVLFRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYAAL--DEETLSRVQALKKNNLLLPISY................................................................................
A0A1U8D6E2_ALLSI/52-241              .........................................................................l-ALMNSMKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.KVD......................................A.--.EDHCRSKQPLRRS.E..---ATDSRNG..EVTDNDS.VA...SSLSAN.TE.EGSST.ERKKQKQKG..........gVNRRRLIKPK.TRER..QR.V.....KDADGVLCRYKKILNTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAE----------------------------------------------dslllpamkepsge..................................................................
A0A0P7XKP7_9TELE/94-323              .........................................................................y-LLITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQern...............................gnyrG.DM.SFYCV--MLESLS.L..LGEEEFFEED..SYLGEEG.MM..pGEEVMA.EN.MSVSN.LGSGSNSGL...........MRRRVFRISR.ARER..QR.V.....KDAAGVLFRYKKILMTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPTKEKLLDYARRCYVAL--DEQTLNKVQELKKNNLLLPISY................................................................................
W5LIG5_ASTMX/63-162                  .........................................................................y-LLITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................E.SN.GNDPRSFSWRRR-.R..ENERDQQAEV..QRSANRQ.SF...SQRP--.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------aqqpptnakvms....................................................................
A0A2I2YTW7_GORGO/55-276              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
G1LAY9_AILME/182-365                 ...............................................................hvsgcpslsls------------------------------.......-----..-----..--..-..---.---......................................-.-P.EDHCRVKPGPRR-.V..DGDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSTM.ERKRQKQKG..........gAGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
K7E861_ORNAN/7-65                    ...............................................................xxxxxxxxxxg------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..------S.PT...SSLSGG.SE.EGGSA.ERKRQKQKG..........gAGRRRFGKPK.ARER..QR.V.....KDADG-------------------------------------------------------------------------------------------------................................................................................
F1RA94_DANRE/3-168                   ......................................................................hlgk------------------------------.......-----..-----..--..-..---.---......................................-.--.----------EKK.K..KKKDTSSDSD..ELPSSSS.SS...SSLSSS.SS.EDERC.HRKKSKKKK...........PPPKRSRSTF.SCST..VR.A.....KSPEDVLKRYKKVLRAYNKEGSMTRAFTKVGVDRNTLALSAVIAEIQIVDPEFYRSLPQFQPQQEKLFEFAQRCSEAL--NTEVKASIFSAKQSGKLLPIKY................................................................................
H2SP95_TAKRU/160-313                 ...................................lvgesgeyleqdayldeeelisgedvlsdvtinsnrppv------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........KRRRLYRA--.PRER..QR.V.....KDAAGVLLRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYTAL--DEETLSRVQALKKNNLLLPISY................................................................................
G3P8Y1_GASAC/66-181                  .........................................................................y-MVITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................G.-Q.EQSFESRRFNWRA.R..-REEDRPSEQ..QKSESQH.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------fpsrqfiqrrpgpptmvpsknhgsnpltnqlasin.............................................
A0A0N4SUE2_DANRE/67-266              .......................................................................ssm------------VEKDKLMLMAQTIQTLKQ.......ERDFL..RQTVL..KL..S..--N.R--......................................-.--.--GAKKVKK----.-..VLDTSTECST..SNTDEES.MT...SSSSSD.SP.DSDIP.RKKRKSH-K...........KTKRASRSKS.TKHS..TR.A.....TTPDDVLRRYNKVFNAYKKEGSISKACAKVGVDRNTLALTAVVAEIQLVDAEFYRSIPKFRTKEEKLFDFAKRCLQSL--TTDLKSVIENAKQERKLLPIKY................................................................................
A0A2K5IWB8_COLAP/20-241              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPAPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
G7NNV3_MACMU/55-276                  .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQRG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
Q1LUD6_DANRE/76-193                  .........................................................................y-LLITSLRAQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FNT.KSRe...................................cnG.TL.EKGTEAEHMQQAT.G..QKQPIKLSTR..KTSTPSP.MM...T-RSGK.IP.VRSQK.RSRKNSQEE...........----------.----..--.-.....------------------------------------------------------------------------------------------------------eeeeeviee.......................................................................
A0A1U8CI38_MESAU/143-209             .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------gggggtefpprtrriqn...............................................................
W5U8A3_ICTPU/133-328                 ......................................................................vpmm------------------------------.......-----..-----..--..T..RSR.QAR......................................S.QT.LKRNKKKNSVQDE.E..-EEEVMEEEE..EYIEEDG.YL...EEEEIV.SN.DDDPN.NKVRKRSRPksrsnggpmrvKRTRVFRIAR.GMER..QR.V.....KDPAGVLFRYKKILVTYQKLRSMSRAFQVHGVDRNTVASTTPIAELLLVAPEKVEEVGEFDSSKEKLLDYARRCYKAL--DETAHAKVQALKKNNLLLPISY................................................................................
A0A2I4BK43_9TELE/71-167              .........................................................................y-MVITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................G.QE.PSQSQYSNGYESR.R..FTWRARRDDD..RPTEQQK.AD...SQ----.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------hfpsrqfiqr......................................................................
H2MW02_ORYLA/1-124                   ........................................................................sq------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.------KKK...........DKRKKKKTQR.EHSR..RR.A.....RHPQEVIKRYKKVLKAYKKGRKLSLAYQKVGVDRNTIVSNAPICELAVVAPKTYKELLGAHTPQQRLQDFSKKCLEVINSDPNLLRDVEHQKKKGKLIPLS-r...............................................................................
I3JJ56_ORENI/89-357                  ..........................................................................FILISNLRAHLYVALEKNAWLQKRIEELEE.......ERNFL..RCQLD..RF..I..VSM.RSPeewsgdaqrgvkvqpasspsppspmttrsgmtlkriqgS.GS.RSRRNAAVTKQEF.H..VEEDKYYTED..EYVEEEE.EE...EEEEED.VD.SSVEK.GIRKKGRGRvcg....eprmKMRRVFRITH.GRER..QR.V.....KDPDGVLIRYKKILSTYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLVAPEKVTEVGEFEASKEKLLDYARRCYKTM--DDETHAKVQTMKKTHKLLPISY................................................................................
H3CRP9_TETNG/186-378                 .........fnsaqsqnllqshshgassttasgggtrpsmsemdeplslvgesgeyleqdayleedelisgedv------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.LSDVT.INGNRPQV-...........KRRRLYRA--.PRER..QR.V.....KDAAGVLLRYKRILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYTAL--DEETLSRVQALKKNNLLLPISY................................................................................
H2P089_PONAB/55-276                  .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHSRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
E2R0G1_CANLF/56-277                  .........................................................................v-ALMNGVRAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRVKPGSRR-.V..EGDGRGGAGG..EASDPES.AA...SSLSGV.SE.EGSTM.ERKRQKQKG..........gAGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
CC106_BOVIN/53-274                   .........................................................................a-ALMNGVRAQLHLALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RLD......................................A.--.DDHCRGKPGPRRA.E..-GDGRGGTGG..EASDPES.AA...SSLSGA.SE.EGSTV.ERKRQKQKG..........gPGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DEETLKKVQALKKSKLLLPITY................................................................................
L5LCE4_MYODS/31-138                  ....................................................................psrgsf------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..-E.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A091E1M5_FUKDA/180-401             .........................................................................l-ALMNGVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRMKPGPRRG.E..-GDSWAGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.DKKRQKQKG..........sASRRRFRKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DEETLKKVQALKKSKLLLPITY................................................................................
E9QPN6_MOUSE/117-337                 .........................................................................l-ALMSSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDYCRMKPGPRRV.D..GDSRA--GVG..EASDPES.AA...SSFSGV.SE.DGSAS.ERKRQKQKG..........sTSRKRFGKTK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
M4AIC6_XIPMA/151-329                 .........................................................irrnitvpavkqefhle------------------------------.......-----..-----..--..-..---.---......................................-.--.---------EDKY.Y..TEEEFVEEEG..EEEVEDD.AD...STVESG.SK.K---K.SRGRGTGEPk.........mKMRRIFRITH.GRER..QR.V.....KDPDGVLIRYKKILSTYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLVAPEKVTDVGEFEASKEKLLDYARRCYKTM--DEETHAKVQSMKKTNKLLPISY................................................................................
U3I2W5_ANAPL/1-40                    ..........................................................................------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....---------------------------------------------------------GEFDPAKERLLEYSRRCFLAL--DPATLQKVQALKKSKLLLP---................................................................................
G3P451_GASAC/120-299                 ......................................................prtrrstavpvkqefhleed------------------------------.......-----..-----..--..-..---.---......................................-.--.-----------KY.Y..TEDEYVEEEE..EDDEDED.ED..sSAEKGS.KK.KGR--.--GRGNAEPr.........mKMRRIFRITH.GRER..QR.V.....KDPEGVMIRYKKILATYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLMAPEKVAEVGEFEASKEKLLDYARRCYKTM--DDQTHAKVQTMKKTHKLLPISY................................................................................
M4AC00_XIPMA/219-394                 .....................................snskhsnaarsslnqlsgrngpdslsllgesdeflee------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-----DG.FI...EEDEGD.DV.MSEAI.STNRQQL--...........KRRRVLRAP-.-RER..QR.V.....KDAAGVLFRYKKILLTYQRLKNMTKAFQIHGVDRNTVASTTPIAELHLVAPEKVAEVGEFDSSKEKLLDYARRCYLAL--DEETLSRVQALKKNNLLLPISY................................................................................
H2SP96_TAKRU/57-280                  .........................................................................y-MVITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSH......................................G.--.QEPGQSQYSNGHG.H..GASAG--GGG..GGSGQRS.SM...SEMSGH.GS.VGPGE.DVLSDVTINsnr.....ppvKRRRLYRA--.PRER..QR.V.....KDAAGVLLRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYTAL--DEETLSRVQALKKNNLLLPISY................................................................................
H2SP95_TAKRU/58-136                  .........................................................................y-MVITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSH......................................G.--.QEPGQSQYSNEQQ.K..SNSQHF----..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------ssrpfiqrr.......................................................................
A0A1S3MI67_SALSA/450-678             .......................................................................lce---IERLRALLSVERSRREQMGETISSLKQ.......DKELL..QQELT..KK..AelICD.FLQ......................................-.--.-DQLRPGMLLLRP.E..KRRGLSSSQM..ELGTGSS.SH...-MGVGF.PD.EGVAF.ENPALFDSFeeve...lhrvMKSSKRSRDG.ENTR..VR.M.....KNVVGVIARYMAALQEFRRSVSMKVAFDRVGVDRNTISRTAAIAELSLAAPEVFHALPPWDEKEETLAHYAHRCRQAM--DDTIRAKIKTMKTKGELLPIV-s...............................................................................
H2M7M4_ORYLA/244-384                 ......................................................meeeelipgedvlsdtinps------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.-----QHQL...........KIRQIFRVPR.ERQR..GK.M.....KDVAGVLFRYKKILLTYQHLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYIAL--DEETLSRVQALKKNNLLLPISY................................................................................
CC106_MOUSE/55-275                   .........................................................................l-ALMSSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDYCRMKPGPRRV.D..GDSRA--GVG..EASDPES.AA...SSFSGV.SE.DGSAS.ERKRQKQKG..........sTSRKRFGKTK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
H0UT87_CAVPO/56-185                  .........................................................................l-ALMNGVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCCMKPGPRRV.E..-GDSRAGAGG..EASDPES.AA...SSLSEA.SE.EGSAS.DRKRQKQKG..........sASRKRFGKPK.ARER..QR.G.....EH----------------------------------------------------------------------------------------------------gsgcvk..........................................................................
M3WF78_FELCA/56-277                  .........................................................................v-ALMNGVRAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRVKPGPRRA.E..-GDGRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAV.ERKRQKQKG..........sAGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
Q1LUD6_DANRE/171-353                 ....................................................................vrsqkr------------------------------.......-----..-----..--..-..-SR.KNS......................................Q.-E.EEEEEEVIEEEEY.I..AEEDYVEEEQ..LITDDDG.NI...SEDKTS.RK.SCTGR.LSGQMRV--...........KRRRVFRFAR.SMER..QR.V.....KDPAGVLLRYNKILVTYQKLKSMSRAFQVHGVDRNTVASTTPIAEMLLVAPEKLSEVGEFDSSKEKLLDYARRCYKAL--DEEAHAKVQTLKKTNLLLPISY................................................................................
G1LAY9_AILME/44-116                  .........................................................................v-ALMNGVRAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.ES.SHP----------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------flestpsapfhmmfspwl..............................................................
A0A2K5M2U4_CERAT/20-241              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQRG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A087XMQ5_POEFO/104-280             .........................................................rrnitvpvkqefhleed------------------------------.......-----..-----..--..-..---.---......................................-.--.-----------KY.Y..TEEEFVEEEE..EEEMEDD.AD...S---PV.ES.GSKKK.SRGRGSGEPk.........mKMRRIFRITH.GRER..QR.V.....KDPDGVLIRYKKILSTYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLVAPEKVTDVGEFEASKEKLLDYARRCYKTM--DEETHAKVQSMKKTNKLLPISY................................................................................
H9H6N1_MONDO/57-277                  .........................................................................l-ALMNSVKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRGKPGPRRA.E..GADGR--GGG..EASDPES.AA...SSLSGG.SE.EGGSA.ERKRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
G3P8X5_GASAC/57-155                  .........................................................................y-MVITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................G.--.-QEQKQQKSESQH.F..PSPSGSSGNG..NSATRSS.M-...SEMSGH.SN.IGPGN.SPRRK----...........----------.----..--.-.....------------------------------------------------------------------------------------------------------................................................................................
A0A286Y8H7_DANRE/437-550             .........................................................................m-LTITKLQCLLESKQERIEALERQVQDLME.......DRKFL..RAQIE..NL..T..GAR.LIS......................................V.--.PEASTSLISESRS.R..KRRRKSSSSS..YINDECF.TD...ESSSTS.SS.EESSS.MRKKRRHKK...........KRKR------.----..--.-.....------------------------------------------------------------------------------------------------------gyvpq...........................................................................
F1RAC3_DANRE/436-549                 .........................................................................m-LTITKLQCLLESKQERIEALERQVQDLME.......DRKFL..RAQIE..NL..T..GAR.LIS......................................V.--.PEASTSLISESRS.R..KRRRKSSSSS..YINDECF.TD...ESSSTS.SS.EESSS.MRKKRRHKK...........KRKR------.----..--.-.....------------------------------------------------------------------------------------------------------gyvpq...........................................................................
A0A0F8ANY5_LARCR/131-227             .........................................................paprrirrefqfpeast------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....SNPDDVLHRYVTILAEFKKHRSVRLASQKFGIDRNTIALTAIIAEMNIADQEKMPP----FDDGDTLAGYSKKCKTVLNEDEEL------------------................................................................................
A0A2I4AZE4_9TELE/81-310              .........................................................................l-LTITKLQCMLESKQERIAALEKQVEDLMQ.......DRKFL..RSQIE..NL..T..SNR.SMPafat..............................pssvL.EV.PKSSKVQPSEK-S.R..KRERA-SSSS..SASSDTG.SE...GSDSSE.VS.AVSSE.HRRKKHH--...........KDKKRSKKGK.DYSR..KR.A.....TGVQYVIQRYRQVLAAFIKKKNMSEAFRHLGIDRNTIANTASIAELHLADKDMVPLVGMFRQGEETLVNYAQRCTMVIDSDAELARKIDQMKANGELLPIS-g...............................................................................
A0A0R4IQP1_DANRE/153-340             ..........................................................vrsqkrsrknssfyfs------------------------------.......-----..-----..--..-..---.---......................................-.KE.EEEEEEVIEEEEY.I..AEEDYVEEEQ..LITDDDG.NI...SEDKTS.RK.SCTGR.LSGQMRV--...........KRRRVFRFAR.SMER..QR.V.....KDPAGVLLRYNKILVTYQKLKSMSRAFQVHGVDRNTVASTTPIAEMLLVAPEKLSEVGEFDSSKEKLLDYARRCYKAL--DEEAHAKVQTLKKTNLLLPISY................................................................................
A0A087XPB0_POEFO/14-249              .........................................................................l-LTITKLQCMLESKQERIAALERQVEDLMQ.......DRKFL..RSQIE..NL..T..TNR.SMApfva..............................pssaT.EA.PKPSKMLHSENKS.R..KRERASSSSS..ASS-DSG.SE...ASDSSD.MS.AASSE.HRRRKHH--...........KDKKRSKKGK.DYSR..KR.VfvpsaTGVLYVINRYKQVLSAFIKKKSMSEAFRHHGIDRNTIANTASIAELHLAGKEMIPLVGQFRQGEETLVNYAQRCTLVIDSDPELSRKIDQMKANGQLLPIS-g...............................................................................
I3K4R8_ORENI/71-180                  .........................................................................y-MVITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................G.QE.QSQSQYSNGYESR.R..FNWRARREED..RPAEQQK.TD...SQ----.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------hfpsrhfmqrrpgpptmvtsknh.........................................................
F1QC35_DANRE/4-130                   ...............................................................lhplerqrsik------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........-ISSKRSRDG.ENTR..VR.M.....KNVVGVIARYMAALQEFRRSVSMKVAFDRVGVDRNTISRTAAIAELSLAAPEIFHALPPWDEKEETLAHYAIRCRQAM--DDSIKAKIKNMKAKGELLPIV-s...............................................................................
M4AC00_XIPMA/71-168                  .........................................................................y-MVINNLRTQLQISVEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................G.PE.QGQSQYSNGYESR.R..FNWRARREED..RPAEQQK.AD...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------qqhfpqrqfvqrr...................................................................
A0A286ZWQ5_PIG/56-277                .........................................................................v-ALMHGVRAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRVKPGTRRV.-..EGDGRGGAGG..EASDPES.AA...SSLSGA.SE.EGSNV.ERKRQKQKG..........gTGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
H9GME2_ANOCA/71-281                  .........................................................................l-TLVTSMRTQLHMALERNSWLQKRIKDLEE.......ERDFL..RCQLD..KF..I..SSA.RLD......................................A.--.DDHFRSKQALRR-.-..--------NG..DATDDDS.MG...SWLTAS.PE.EGGST.EHKKQKGG-...........TNRRRFVKPK.MRER..QR.V.....KDVDGVLCRYKKILYTFQKLQSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDSSKERLLEYSRRCFMAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A0R4ICJ2_DANRE/72-226              ......................................................esltsdravspackrvqskn------------------------------.......-----..-----..-L..S..SSS.---......................................G.AL.SLRCETVNSPALT.A..SSSTIVTSQK..NQSTDTS.SD...SSESTD.SS.DSEPT.AKKKKKGKK...........SKRQKKSKTK.MIDI..KR.V.....RIPEDSINRYNKVLQLVRDGLSKAEAYNKVKIDRNTIVMQVPIAELATANP---------------------------------------------------pnss............................................................................
G3P451_GASAC/31-133                  ..........................................................................FILVSNLRAHLYVTLEKNAWLQKRIEELEE.......ERNFL..RCQLD..RF..I..VSL.RGP......................................E.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------ewcgdaqrgvkvqpasspsppspmttrsgmtlkrlqgsgprtrrstavpvkqe...........................
H3AFM0_LATCH/1-101                   ........................................................................av------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....-GVQQVVKRYKKALKLYQKYGSMAKAYGYLNVDRNTIVNTAPIAELFLADSNKFEQIGALKPSKETLRQFAARCADAI--DESIKMKIDAMKEMGHLLPIS-g...............................................................................
I3K5V8_ORENI/13-238                  .........................................................................t-ALLNKEQEELTFLKEKLEWQKMRIEELEG.......ERDFL..RRQLS..SF..T..-SM.KLD......................................L.FP.HKLTKSSEQPKDQ.P..FNDPFSLKAS..ENSDSSS.AF...SSVSSV.WS.SSSSF.PKKRKQKYKk........khSRAKKPKKEQ.KKLR..QH.V.....QTPNDIVQRCKSPLKTFPRTKTMTKAFQKHGLDRNTVVSTSSVGELAIAVPNVYQELLSNRSSGETVLAFAKRCEAAIQGSDEV--KKQNRNASAIFKRLVY................................................................................
Q1LUD5_DANRE/58-185                  .........................................................................y-LLITSLRAQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FNT.KSRe...................................cnG.TL.EKGTEAEHMQQAT.G..QKQPIKLSTR..KTSTPSP.MM...T-RSGK.IP.VRSQK.RSRKNSQEE...........EE--------.----..--.-.....------------------------------------------------------------------------------------------------------eeevieeeeyiaeedyv...............................................................
A0A2I3RLM6_PANTR/47-268              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
Q5EB04_DANRE/63-163                  .........................................................................y-LLITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................E.SN.GTDSRSFSWRRRR.E..NDRDQQAESQ..RLANRQS.FQ...-QRPTQ.Q-.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------tsanpkvlss......................................................................
A0A0F8AEI7_LARCR/256-398             ......................................................edgyleeeemisgedvmadt------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.INSNRHQ-L...........KRRRVFRAP-.-RER..QR.V.....KDAAGVLFRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYTAL--DEETLSRVQALKKNNLLLPISY................................................................................
A0A1L8FGN5_XENLA/55-274              .........................................................................i-ILMNSMNTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLN..KF..I..SFA.KLD......................................S.--.EDQSRAKQTNWR-.-..-SDGKECCIE..DLTDNES.ML...S-VSTY.SE.EVDTL.ANTKRRKQKg.........nCNQKGFCKPK.VRER..QR.V.....KDADGVLCRYKKILSTFQKLKSMSRAFEHHCVDRNTVALTTPIAELLIVAPEKIAEVGEFDPSKERLLEYSRRCFLAL--DEETLEKVQALKKNKLLLPITY................................................................................
A0A2I3HHB6_NOMLE/20-241              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
E9QE99_DANRE/234-449                 ........................................................................ql--SLEQAKKTIEIQKEKILHLQEKVDFLMD.......DRNYL..RSRLE..DA..L..---.---......................................-.--.RLRCETVNSPALT.A..SSSTIVTSQK..NQSTDTS.SD...SSESTD.SS.DSEPT.AKKKKKGKK...........SKRQKKSKTK.MIDI..KR.V.....RTPEDSINRYNKVLQLVRDGLSKAEAYNKVKIDRNTIVKQAPIAELATANPTEFKSLRATFKKGESVQEFANLCLTRCLAQSNM-EILKQLKESNALLDI--fk..............................................................................
A0A1U8DI13_ALLSI/56-241              .........................................................................l-ALMNSMKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.KVD......................................A.--.EDHCRSKQPLRRS.E..---ATDSRNG..EVTDNDS.VA...SSLSAN.TE.EGSST.ERKKQKQKG..........gVNRRRLIKPK.TRER..QR.V.....KDADGVLCRYKKILNTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEDAQCR-----------------------------------------dsssr...........................................................................
G3VFQ8_SARHA/57-277                  .........................................................................l-ALMNSVKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRGKPGPRRA.E..--GTEGRGGG..EASDPES.AA...SSLSGC.SE.EGGSA.ERKRQKQKG..........gAGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A1U8D6E1_ALLSI/56-245              .........................................................................l-ALMNSMKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.KVD......................................A.--.EDHCRSKQPLRRS.E..---ATDSRNG..EVTDNDS.VA...SSLSAN.TE.EGSST.ERKKQKQKG..........gVNRRRLIKPK.TRER..QR.V.....KDADGVLCRYKKILNTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAE----------------------------------------------dslllpamkepsge..................................................................
A0A1A6GKP9_NEOLE/170-296             .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRMKPGPRRV.D..-GDSRAGVGG..EASDPES.AA...SSFSGA.SE.EGSAS.ERKRQKQKG..........sTXRRRFGKPK.ARER..QR.-.....------------------------------------------------------------------------------------------------------gewvpv..........................................................................
H2QH75_PANTR/55-276                  .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A0A0MUL9_PAPAN/55-276              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQRG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A2I4ALP3_9TELE/65-281              ........................................................................av--ELTKLKQQTKMDKQKIEYLEDRIKYLEEanrelknDKEFL..LTQIK..EA..T..MSP.AST......................................S.-S.RKTAQV-------.L..PSSSTSPTPS..ASSTDFS.S-...--LSSS.EE.E---E.EKEKKKMKS...........KKKKSKKHRD.SYSR..SR.M.....TTVDGVITRYENALKRFNKFGSMKKAFTKINVDRNTIARTAAIAELAITFPDTFKELLPRKEDNEKISQFAERCRKAI--TKEMAETITAKKKIGKLLPIMY................................................................................
A0A1S3M394_SALSA/137-329             ........................................spmttrsgmlrkhvqsqphtcssrvpvkqevrvi------------------------------.......-----..-----..--..-..---.---......................................-.--.-------EEDKY-.-..FEEDGYMEEE..EVEEEDD.S-...SDEKMS.KK.KGS--.--------Kngg....eprmKMRRVFRITR.GKER..QR.V.....KDPDGVLHRYQKILLTYQRLRSMSKAFQVHRVDRNTMASTSPIAELLLVAPEKVAEVGEFESSKEKLLDYARRCYKAL--DEPMHAKVAAMKKNHLLLPISY................................................................................
A0A2I3M9V6_PAPAN/20-241              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQRG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A0F8AEI7_LARCR/69-164              .........................................................................y-MVITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSH......................................G.QE.QSQSQYSNGYESR.R..FNWRARREDD..RPAEQQK.TD...SQ----.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------hfpsrpfiq.......................................................................
A0A087XYJ3_POEFO/183-368             .......................hstssttgsgsnsknnnaarsslnqlsglnvpdslsllgesdefleedgfi------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...EEDEGD.DV.MSQAI.STNRQQL--...........KRRRVLRAP-.-RER..QR.V.....KDAAGVLFRYKKILLTYQRLKNMTKAFQIHGVDRNTVASTTPIAELHLVAPEKVAEVGEFDPSKEKLLDYARRCYLAL--DEETVSRVQALKKNNLLLPISY................................................................................
A0A0G2KLC0_DANRE/1-178               ......................................................................meni------------------------------.......-----..-----..--..-..---.---......................................-.--.--HVKNKEKPADM.P..KRTKHSLEDS..ESASADS.SE...SSDSES.SS.SDSSR.ERKKKKVKKg.........kKRVKKMKKSK.HESKffPR.V.....TEPWQVVKRYKAVLEIFDRGSNMTYAFRKYGVDRNTIVQTAVIAELAIAAPEKYSEIQNN--RGEKLSTITQKCQDAIMADKSIAHKIQAMKKEGKLHPI--rk..............................................................................
S7NJX5_MYOBR/46-148                  ........................................................................da------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A2D0SN53_ICTPU/336-561             .......................................................................aye---IERLKALLQVEKNKSMMLGETISSLKQ.......DKELL..QQELT..KKaeL..ICE.FLQ......................................D.QL.RPDKRRVHSSSQM.E..AGSSHQLISSfpDEGAPFE.SP...ALFDSF.EEvEVHPL.DRQRTIK--...........LSS-KRNRDG.ENTR..VR.M.....KNVVGVIARYMTALQEFRRSVSMKVAFDRVGVDRNTISRTAAIAELSLAAPEVFHALPPWDEKEETLAHYAVRCRQAM--DENIKAKIKAMKARGELLPIV-s...............................................................................
H2TIT7_TAKRU/1-228                   .........................................................................l-LTITKLQCMLESKQERIAALEKQVEDLMQ.......DRKFL..RTQVE..NL..T..SSR.SMQaf.................................appT.EA.PKPSKGQHSDGKS.R..KRERASCSSS..DGS-PSG.SE...ASDSSE.AS.AASSE.HRRKKHH--...........KEKKRSKKTK.DYSR..KR.A.....TGVQYVIHRYKQVLTAFVKKKNMSEAFRHLGIDRNTIANTASIAELHLAGVDFVHLVGRFRQGEETLVNYAQRCTMVIDSDSDLSQKIDQMKANGELLPIS-g...............................................................................
A0A1S3Q934_SALSA/83-315              .........................................................................m-LTITKLQCMLESKQERIAALERQVEDLQQ.......DRKFL..RSQIE..NL..T..SQR.SVPtftt.............................tatsaA.EA.PKAGKSLYSEPKP.R..KRERVASSSS..SFSNESG.SE...MSVSTV.MS.GASSD.HKKRRHH--...........KDRRRGKKGK.DYSR..KR.A.....TGVQYVIHRYKQVLSAFIKKKSMSGAFRHYGIDRNTIANTASIAELYLAAKETLPLVGMFRPREETLVSYAQKCALVIETDVALARKIEQMKATGELLPIT-v...............................................................................
G7PZ00_MACFA/55-192                  .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..G--DSGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQRG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTF-------------------------------------------------------------------------------------................................................................................
F7EH53_XENTR/55-274                  .........................................................................i-ILMNSMKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SCT.KSD......................................S.--.EEHSRIKQTNWR-.-..-SEGKECCNE..DLTDNDS.ML...S-VSAY.SE.EGDTL.ADTKRQRQKg.........sCNKRGFCKPK.IRER..QR.V.....KDADGVLCRYKKILSTFQKLKSMSRAFEHHRVDRNTVALSTPIAELLIVAPEKIAEVGEFDPSKERLLEYSRRCFLAL--DEETLEKVQTLKKNKLLLPITY................................................................................
H3CJE2_TETNG/8-85                    ..........................................................................FILVSNLRAHLYVALEKNAWLQKRIEELEE.......ERNFL..RCQLD..RF..I..VSM.RGP......................................E.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------gkraplllwfsdqhnrekssfiyqiklh....................................................
A0A0D9S616_CHLSB/55-276              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
B5X442_SALSA/71-175                  .........................................................................y-LLITNLRTQLQISLEKNSWLHKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KTQ......................................G.HQnQGPSESQYSNG--.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------ydtrrfewkprregerpaeqksepqrftsrqifqrrpspta.......................................
A0A140LGL1_DANRE/17-183              .......................gstssncssnnrslnelqeslsllgdeeddyledsyleeeemmsgedvitd------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...--NMTL.RS.IGAAG.RHTGS---Rp........alKRRRVFRIAR.GRER..QR.V.....KDAAGVLFRYKKILVTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKLAEVGEFDPSKEKLLDYARRCYIAL------------------------d...............................................................................
A0A140LH77_DANRE/63-157              .........................................................................y-LLITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................E.SN.GTDSRSFSWRRRR.E..NDRDQQAESQ..RLANRQS.FQ...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------qrptqqtsan......................................................................
A0A2I4CJY3_9TELE/179-358             ........................................................niavpvkqefhveegkyy------------------------------.......-----..-----..--..-..---.---......................................-.--.--------TEDEY.V..EEEEEEEGEE..EEEENDD.DS...SVDKVL.KK.KGKGR.AGGEPRV--...........KMRRIFRITH.GRER..QR.V.....KDPDGVLIRYKKILSTYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLVAPEKMTEVGEFEASKEKLLDYARRCYKTM--DDETHAKVQGMKKTHKLLPISY................................................................................
H2T1A1_TAKRU/12-228                  ..........................................................................FILVSNLRAHLYVALEKNAWLQKRIEELEE.......ERNFL..RCQLD..RF..I..VSM.RSS......................................-.--.EDWCGEEPSATRD.E..YVEEEEDDDD..EEE--DE.AS...SSEKGL.KK.KGRGR.ANSEPRM--...........KMRRIFRITH.GRER..QR.V.....KDPDGVLIRYKKILTTYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLVAPEKMTEVGEFEASREKLLDYARRCYKTM--DEQTHTKVQAMKKTHKLLPISY................................................................................
A0A2K5M2V5_CERAT/55-276              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQRG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
H3AFM1_LATCH/3-166                   .................................................................hlgesnqgc------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..------TELS..NNSLESG.SD...GEDSES.MT.SSSSDlPKRQKHSYR...........KKKKTRKSES.SFSR..GTlI....pDSEEQVVKRYKKALKLYQKYGSMAKAYGYLNVDRNTIVNTAPIAELFLADSNKFEQIGALKPSKETLRQFAARCADAI--DESIKMKIDAMKEMGHLLPIS-i...............................................................................
A0A2D0RG94_ICTPU/230-377             ...........................................dlmsgedvmpenmtirnmgapgrppgghpal------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........KRRRVFRIAR.GRER..QR.V.....KDAAGVLFRYKKILVTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKLAEVGEFDPSKEKLLDYARRCYIAL--DPQTRSKVQALKKNNLLLPISY................................................................................
L5KF71_PTEAL/56-298                  .........................................................................v-ALMNGVRAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMDadrsltsll...................ppqlkayvspS.SP.EDHCRVKPGPRRV.-..EGDGRGGAGG..EASDPES.AA...SSVSGA.SE.EGSNV.DRKRQKQKG..........gTGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
I3K3F3_ORENI/7-216                   ....................................................................adrrks--------QELEICKMRLEWQKDKIDELTK.......ERDYL..KEQLA..AS..L..-S-.---......................................-.--.KEPTSSVQDSSEV.L..---SISSLSS..DGSFDES.SN...SSMSTT.SS.DED--.RKKRKKGKA...........KKHKKSKKRD.QKQR..KR.G.....KNPKQVVTRYNKILRLFKRGGTMSAAFKRLGVDRNTIVATAPIAELFIVAPERYKELEKNM-QGQKLSLFATQCAAAISADPETEEKFKAYKSSGKLLPL--kt..............................................................................
B8JI21_DANRE/67-230                  .......................................................................ssm------------VEKDKLMLMAQTIQTLKQ.......ERDFL..RQTVL..KL..S..--N.R--......................................-.--.--GAKKVKK----.-..VLDTSTECST..SNTDEES.MT...SSSSSD.SP.DSDIP.RKKRKSH-K...........KTKRASRSKS.TKHS..TR.A.....TTPDDVLRRYNKVFNAYKKEGSISKACAKVGVDRNTLALTAVVAEIQLVDAEFYRSIPKFRTK---------------------------------------e...............................................................................
A0A151MGJ0_ALLMI/52-233              .........................................................................l-ALMNSMKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.KVD......................................A.--.EDHCRSKQPLRR-.-..-SDATDSRNG..EVTDNDS.VA...SSLSAN.TE.EGSST.ERKKQKQKG..........gVNRRRLIKPK.TRER..QR.V.....KDADGVLCRYKKILNTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAE----------------------------------------------dsllpp..........................................................................
F7IHD1_CALJA/55-276                  .........................................................................r-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRVKPGPRRI.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.EKRRQKQKG..........gARRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
V8PET9_OPHHA/76-293                  .........................................................................l-TLVTSMKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RLD......................................A.--.DDHCCKKKLPRRA.E..IMESR---NG..EVTDDDS.MA...SWLTAS.PE.EGGSV.EHKKLIAG-...........LNRRCFAKPK.IRER..QR.V.....KDVDGVLCRYKKILYTFQKMQSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFMAL--DDETLKKVQALKKSKLLLPITY................................................................................
K7EMI9_HUMAN/20-241                  .........................................................................l-ALMNSVKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A1S3N371_SALSA/71-186              .........................................................................y-LLITNLRTQLQISLEKNSWLHKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KTQ......................................G.HQnQGPSESQYSNG--.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------ydsrrfewkprregerpaeqksepqrftsrqifqrrpsptamappknhtsst............................
A0A1S3N371_SALSA/239-391             ...........................................................lgeseefleqegymn------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..----EEE.MI...SGEDGM.SE.GMSSG.G----HPGM...........KRRRVFRFT-.-RER..QR.V.....KDAAGVLFRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAEMLLVAPEKVAEVGEFDPSKEKLLDYARRCYVAL--DEETLSRVQALKKNNLLLPISY................................................................................
A0A140LIV9_MOUSE/3-65                .............................................................pgprrvdgdsrag------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..--------VG..EASDPES.AA...SSFSGV.SE.DGSAS.ERKRQKQKG..........sTSRKRFGKTK.ARER..QR.-.....------------------------------------------------------------------------------------------------------................................................................................
A0A1S3RYE2_SALSA/216-393             ............................sssanratmsdmnahgsigpdslsllgeaeefleqdgymneeemis------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...--GEDV.MS.EGMSS.GG---HPGM...........KRRRVFRIT-.-RER..QR.V.....KDAAGVLFRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAEMLLVAPEKVAEVGEFDPSKEKLLDYARRCYVAL--DEETLSRVQALKKNNLLLPISY................................................................................
W5LL15_ASTMX/56-274                  .........................................................................m-LTITKLQCLLESKQEKIESLERQVEDLQQ.......DRKFL..RQQIE..NL..T..SSR.S--......................................G.PA.PEASKSVYTEPKA.H..KRQRTASSSS..SLCNESG.SD...GSFSSA.SS.AAS--.-ERKRRH--...........KEKKKGKKGK.DYGR..KR.A.....TGVQYVIHRYKQVLSAFNKKKSMSGAFRHHGIDRNTIANTAPIAELHLAAKEAVPLVGQFRPREETLVNYAQRCALAIETDEELSRKIEQMKANGELLPIS-a...............................................................................
A0A2K5IWB3_COLAP/55-276              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPAPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
I3K1U1_ORENI/1-204                   ..........................................................................---------------EKLEWQKMRIEELEG.......ERDFL..RRPLS..SF..T..---.---......................................T.--.HKLTKSSKQCKDE.P..FNDLFSSKAS..ENSDSSS.AS...SCVSSV.WS.SSSSS.PKKRKHKYKk........khSRAKKPKKEQ.KKLQ..QR.V.....QAPNDIVQRHKSLRKTFPKTKTMTKAFQKHGLDRNTVVSTSSVGELAIAVPNVYQELLSNRPSREMVLAFAKQCVAAIQGSDEVKNKTESMKTAGTLLPI--................................................................................
A0A0R4IQP1_DANRE/58-190              .........................................................................y-LLITSLRAQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FNT.KSRe...................................cnG.TL.EKGTEAEHMQQAT.G..QKQPIKLSTR..KTSTPSP.MM...-TRSGK.IP.VRSQK.RSRKNSSFY...........----------.----..--.-.....------------------------------------------------------------------------------------------------------fskeeeeeeevieeeeyiaeedyv........................................................
A0A140LIX8_MOUSE/55-109              .........................................................................l-ALMSSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.ED.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------ycr.............................................................................
A0A1S3WRP0_ERIEU/55-272              ........................................................................vp--LMDGVRAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RPE......................................A.--.EDHCRGKPGPRRV.E..ADG---RGGP..EASDPES.AA...SSVSAA.SS.EGSAG.ERKRQRQ-K...........GAGRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPTKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
H0WVU5_OTOGA/56-277                  .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.DDHCRVKPGPRRA.E..-GDSRAGAAG..EASEPES.AA...SSFSAA.SE.EGSAG.ERRRQRQKG..........gASRRRLGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLQKVQALKKSKLLLPITY................................................................................
I3MQK5_ICTTR/56-275                  .........................................................................l-ALMNGVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................T.--.EDHCRVKPGPRRV.E..---GDSRAGG..EASDPES.PA...SSLSGV.SE.EGSAG.ERKRRNQKG..........nAGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
H3CRP9_TETNG/61-160                  .........................................................................y-MVITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSH......................................G.QE.QRQSQYSNGFEPR.R..FTWRARRDEE..RPAEQQK.SN...S-----.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------qhfpsrqfiqrrpv..................................................................
G3TMP8_LOXAF/56-275                  .........................................................................l-ALMNGVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRVKPGPRRV.E..---GDSRGGA..EASDPES.AA...SSLSGG.SE.EGNSS.ERKRQKQKG..........gTGRRRFSKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHCVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DEETLKKVQALKKSKLLLPITY................................................................................
L9KUA1_TUPCH/46-267                  .........................................................................r-ALMNGVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RGD......................................A.--.EDHCRVKPGPRRA.E..-GDSRAGAGG..EASDPES.AA...SSLSGV.SE.EGSAG.ERKRQRQKG..........sTGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A1S3RYE2_SALSA/71-170              .........................................................................y-LLITNLRTQLQISLEKNSWLHKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KTQ......................................G.HQnQGPSESQYSNG--.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------ydtrrfewkprregerpaeqksepqrftsrqifqrr............................................
Q5EB04_DANRE/192-378                 ........................stssncssnnrslnelqeslsllgdeeddyledsyleeeemmsgedvitd------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...--NMTL.RS.IGAAG.RHTGS---Rp........alKRRRVFRIAR.GRER..QR.V.....KDAAGVLFRYKKILVTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKLAEVGEFDPSKEKLLDYARRCYIAL--DPQTLCKVQALKKNNLLLPISY................................................................................
A0A087XYJ3_POEFO/72-169              .........................................................................y-MVINNLRTQLQISVEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................G.PE.QGQSQYSNGYESR.R..FNWRARREED..RPAEQQK.AD...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------qqhfpqrqfvqrr...................................................................
A0A1U7R6L1_MESAU/2-167               .................................................................kpgprrvdg------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..--DSRTGVGG..EASDPES.AA...SSFSGA.SE.EGGAG.ERKRLKLKG..........sSGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A2I3HFV7_NOMLE/55-276              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
K7EMP7_HUMAN/55-172                  .........................................................................l-ALMNSVKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARE-..--.-.....------------------------------------------------------------------------------------------------------................................................................................
H3AGC2_LATCH/55-268                  .........................................................................q-MFMTNLRNQLNLTLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SST.KSD......................................A.VS.EYESRMKQNLR--.-..--------NG..NISDDED.GL...GTQSPS.SD.AGCSE.LDRKKLRGR..........gARGKQPLRVK.VRDR..QR.V.....KDAEDVLCRYKKILTSFQKLKSMSRAFEYHGVDRNTVALTTPIAELLIVAPEKVAEIGEFDSSKERLLEYSKRCFMAL--DEETLMKVQALKRNKLLLPISY................................................................................
W5KQ74_ASTMX/66-200                  .........................................................................y-LLMTNLRAQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FTT.KSQ......................................E.RS.GKY----------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------ipkkweticykcrgrgielhpeagqqhtpqktasrraltppptpmmtrsgqipsrnhslkkrkirnssaqdnqfshkprh
I3K0S3_ORENI/1-215                   ..........................................................................---------ELEICKMRLEWQKDKIDELTK.......ERDYL..KEQLAacNF..V..CVV.FLT......................................-.--.VLLALSKEPTSSV.Q..DSSEVLSISS..PSSDGSV.DE...SSDSSM.ST.TSSDE.DRKKRKKGK...........AKKHKSKKHD.KKQR..TR.G.....KNPKQVVTRYNKILRLFRRGGTMSAAFKHLGVDRKTIVATAPIAELFIVAPERYKELEKNKQGQKRSL-FATQCAAAISADPETEEKFKAYKSSGKLLPL--kt..............................................................................
A0A0F8CLD8_LARCR/20-222              ......................................................................svsm----------VEFLEAKIQWQDKLIKDLEE.......ERNFL..RAQVQ..GE..R..---.-KK......................................T.--.LKHPKVLKMAVD-.-..YEDDGHMDDG..DDLSPSS.PN...ISDSS-.--.D--SD.TPRRKPH-P...........TQSPPGATAS.GRGH..MR.V.....KGPDEAIRRYQRVLKTFSRVRTMSEAFRINGVDRGTIKMTAPIAELKIVDPDTFNTL-KFNPATDTLMSFAKKCAAHI--SSEKRVIIEDMKSRGKLLPL--lm..............................................................................
H2M3P9_ORYLA/40-153                  .......................................................................qlv---TKQQQQQIKKLTEKIQRQEELIKELSA.......EKDFL..KEQLA..KH..P..PQA.STN......................................-.DI.MLHGKQQKTSQVQsS..SSASTSSSSS..DSSDSSC.SN...SSSDSS.SE.SSSSD.EEKKKKKKN...........GKKKK-----.----..--.-.....------------------------------------------------------------------------------------------------------gt..............................................................................
M3Y7B6_MUSPF/189-368                 ..................................................................slslylfp------------------------------.......-----..-----..--..-..---.---......................................-.--.EDHCRVKPGPRRV.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSTV.ERKRQKQKG..........gAGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
M3Y7B6_MUSPF/44-122                  .........................................................................v-ALMNGVRAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RVD......................................A.GP.QDQLLS-------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------cstpatadgqnlvaspsqgln...........................................................
D4AAV8_RAT/114-335                   .........................................................................l-ALMNSVKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRMKPGPRRA.D..-GDSRAGVGG..EASDPES.AA...SSFSGL.SE.EGSAS.ERKRQKQKG..........sAGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A0G2L3D6_DANRE/11-226              .........................................................................s-IALAKAKAEIETWRVKCQNLEDKINDLTK.......ESDYL..REQLS..DA..I..KME.N--......................................-.--.-IHVKNKEKPVDM.P..KRTKHSLEDS..ESASADS.SE...SSDSES.SS.SDSSR.ERKKKKV--...........KKGKKRVKKK.KKSK..HE.I.....TEPWQVVKRYKAVLEIFDRGSNMTYAFRKYGVDRNTIVQTAVIAELAIAAPEKYSEIQNN--RVEKLSTITQKCQDAIMADKSIAHKIQAMKKEGKLLPIS-f...............................................................................
M4AIC6_XIPMA/55-142                  ..........................................................................FILISNLRAHLYVSLEKNAWLQKRIEELEE.......ERNFL..RCQLD..RF..I..VSM.RSP......................................D.--.G------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------nsvadwsgeaqravkvqpasspsppspmttrsgmtlk...........................................
G5BVY2_HETGA/98-319                  .........................................................................l-ALMNGVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRMKPGPRRV.E..-GDSWAGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.DKKRQKQKG..........sASRRRFRKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A2I2Z4C8_GORGO/20-241              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
F1Q991_DANRE/198-237                 .........................................................................q-LSLEQAKKTIEIQKEKILHLQEKVDFLMD.......DRNYL..RSRLE..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------................................................................................
A0A1U8DGL1_ALLSI/56-275              .........................................................................l-ALMNSMKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.KVD......................................A.--.EDHCRSKQPLRRS.E..---ATDSRNG..EVTDNDS.VA...SSLSAN.TE.EGSST.ERKKQKQKG..........gVNRRRLIKPK.TRER..QR.V.....KDADGVLCRYKKILNTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A1S3LU78_SALSA/23-161              ...................................................ensalfesfeeveihpldrhrvm------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........-KSSKRSRDG.ENTR..VR.M.....KNVVGVIARYMAALQEFRRSVSMKVAFDRVGVDRNTISRTAAIAELSLAAPEVFHALPPWDEKEETLAHYAHRCRQAM--DDTIRAKIKTMKTKGDLLPIV-s...............................................................................
A0A1U7SZW5_TARSY/56-276              .........................................................................l-ALMNGVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SST.RMD......................................A.--.EDHCRAKPGPRR-.-..EGDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKA..........gAGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
A0A286XTQ6_CAVPO/1-66                ..................................................................mkpgprrv------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..EGDSRAGAGG..EASDPES.AA...SSLSEA.SE.EGSAS.DRKRQKQKG..........sASRKRFGKPK.ARER..QR.-.....------------------------------------------------------------------------------------------------------................................................................................
H2T1A2_TAKRU/8-126                   ..........................................................................FILVSNLRAHLYVALEKNAWLQKRIEELEE.......ERNFL..RCQLD..RF..I..VSM.RSS......................................E.--.GEDARLLQSHSVF.L..IHHNLSDW--..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------cgdsqrsvkgqpagspsppspmttrsgmtlkhiqgagsrsrrsaait.................................
H2SP97_TAKRU/209-370                 ...........................ssmteplslvgesgeyleqdayldeeelisgedvlsdvtinsnrppv------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........KRRRLYRA--.PRER..QR.V.....KDAAGVLLRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYTAL--DEETLSRVQALKKNNLLLPISY................................................................................
I3K4R8_ORENI/249-401                 ....................................................lgesdeyleqdgyieeeeemis------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...--GEDV.MS.DA---.INSNRHQ-L...........KRRRVFRPP-.-RER..QR.V.....KDAAGVLFRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYTAL--DEETLNRVQALKKNNLLLPISY................................................................................
A0A1S3M394_SALSA/57-135              ..........................................................................FMLITNLRTHLCVSLEKNSWLQKRIEDLEE.......ERNFL..RCQLE..RF..V..SSM.RTP......................................E.SN.HVYPESQ------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------htslnyttlkppperapspp............................................................
I3J4U8_ORENI/1-175                   .........................................................................e---------KLTFLKEKLEWQKKRIEELEG.......ERDFL..RSQLS..SL..T..---.---......................................-.--.-------KQPKDE.P..FNDPFSSKAS..ENSDSSS.AS...SSVSSV.WS.SSSSS.PKKRKEKYKk........khSRAKKPKKEQ.KKFR..QR.V.....QTPNDIVQRYKSLLKTFPKTKTMTKGFRKHGLDRNTVVSTSSVGELAIAVPNVYQELLSNRPSGETVLAFAK------------------------------................................................................................
G3P462_GASAC/63-174                  ..........................................................................FILVSNLRAHLYVTLEKNAWLQKRIEELEE.......ERNFL..RCQLD..RF..I..FTT.RES......................................-.PM.TEAMKHAAHSP--.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------vtewcgdaqrgvkvqpasspsppspmttrsgmtlkrlqgsgprtrrstav..............................
A0A0F8AGQ1_LARCR/50-262              ........................................................................al--MVAKLKEQQKLDQQKIAYLEDRIKHLEE.......TNSEL..RNDKD..FL..V..--A.Q--......................................-.--.-IKGAPKESPSTS.T..SGSGKTLPVL..PLSSTSS.SP...S--STQ.SS.SSSSE.EEKKKMK--...........KRAKKSRKHHvPTSR..SR.M.....TSIEGVIHRYKAALKKLNKCGSMKKAFSRIHVDRNTIARTAVIAEIAIMFPDTFQDLLSRHDENETISQFAENCTKAV--TTEMAEKITAEKKRGKLLPIVY................................................................................
A0A0G2L4Z1_DANRE/1-202               .........................................................................i-------------------------SDLTK.......ETDSL..QQQFG..QS..T..DDGwTID......................................-.-T.SFSAKLSPGASSF.S..LSSSPSSSSS..SSSPSSS.SS...CSLSSSsTD.SSDSD.KKSKKRRKK...........KKKHHHQSHK.KKDK..IS.A.....RHPEEVIKRYSKVLKAYKKGKKLSVAYRKVGVDRNTIVANAPICELAVVAPKKYKELLVAHTPQQRLQDFAKKCLEVFNNDPNLLRDVEHQKKKGKLIPLS-t...............................................................................
A0A096LTA3_POEFO/88-199              ...............................................................ssstnlssmct------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.L.....TNVNGVVARYQKALKTFTKYGSMKRAFWKINVDRNTIARTAVIAELAITFPDVFKELIAVKVEQEKICELADRCRKAI--TNEMAETITSKKRSGKLLPIM-h...............................................................................
G3RHZ6_GORGO/55-276                  .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
CC106_HUMAN/55-276                   .........................................................................l-ALMNSVKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
I3K5W0_ORENI/56-261                  .........................................................................t-ALLNKEQEELTFLKEKLEWQKMRIEELEG.......ERDFL..RRQLS..SF..T..---.---......................................-.--.-------KQPKDQ.P..FNDPFSLKAS..ENSDSSS.AF...SSVSSV.WS.SSSSF.PKKRKQKYKk........khSRAKKPKKEQ.KKLR..QH.V.....QTPNDIVQRCKSPLKTFPRTKTMTKAFQKHGLDRNTVVSTSSVGELAIAVPNVYQELLSNRSSGETVLAFAKRCEAAIQGSDEV--KKQNRKY---------egrw............................................................................
S9XEE2_CAMFR/56-261                  .........................................................................v-ALMNGVRAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRVKPGLRRV.E..-GDGRGGAGG..EASDPES.AA...SSLSGA.SE.EGSNI.ERKRQKQKG..........gTGRRRFSKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLI----------------ERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
I3K1U2_ORENI/1-204                   ..........................................................................---------------EKLEWQKMRIEELEG.......ERDFL..RRPLS..SF..T..ISV.ILH......................................P.--.AEQC------KDE.P..FNDLFSSKAS..ENSDSSS.AS...SCVSSV.WS.SSSSS.PKKRKHKYKk........khSRAKKPKKEQ.KKLQ..QR.V.....QAPNDIVQRHKSLRKTFPKTKTMTKAFQKHGLDRNTVVSTSSVGELAIAVPNVYQELLSNRPSREMVLAFAKQCVAAIQGSDEVKNKTESMKTAGTLLPI--................................................................................
H2T1A2_TAKRU/133-322                 ................................................................trgkfqsfss------------------------------.......-----..-----..--..-..--R.LCS......................................S.FS.QLPSSRSFTEEEK.F..FTEDEYVEEE..EDDDDEE.EDeasSSEKGL.KK.KG---.-RGRANSEPr.........mKMRRIFRITH.GRER..QR.V.....KDPDGVLIRYKKILTTYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLVAPEKMTEVGEFEASREKLLDYARRCYKTM--DEQTHTKVQAMKKTHKLLPISY................................................................................
X1WFI5_DANRE/40-234                  .......................................................................qps-------------------------ESLTS.......DRAVLpaRKRVQ..SK..N..LSS.SS-......................................G.AL.RLRCETVNSPALT.A..SSSTIVTSQK..NQSTDTS.SD...SSESTD.SS.DSEPT.AKKKKKGKK...........SKRQKKSKTK.MIDI..KR.V.....RTPEDSINRYNKVLQLVRDGLSKAEAYNKVKIDRNTIVKQAPIAELATANPTEFKSLRATFKKGESVQEFANLCLTRCLAQSNM-EILKQLKE---------................................................................................
A0A1L8FMT4_XENLA/404-623             .........................................................................i-ILMNSMNAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SST.KSD......................................S.--.EDHSRVKQTNWR-.-..-SEGKECCNE..DLTDNES.M-...VSVSAY.SE.EGDTL.ADTKRQKQKg.........nCYKKVFCKPK.IRER..QR.V.....KDADGVLCRYKKILSTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKIAEVGEFDPSKERLLEYSRRCFLAF--DEETLEKVQALKKNKLLLPITY................................................................................
W5NSK7_SHEEP/120-341                 .........................................................................a-ALMNGIRAQLHLALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RLD......................................A.--.GEFTRPLPGEDRA.G..-GGGGGGTGG..EASAPES.AA...SSVSGA.SE.EGSTM.ERKRQKQKG..........gPGRRRFGKPK.VRER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DEETLKKVQALKKSKLLLPITY................................................................................
H3CJE2_TETNG/136-322                 ..................................................mtlkrnqgsgsrsrrsaavageap------------------------------.......-----..-----..--..-..---.---......................................-.--.--------SARLA.A..VKQEFHLEEE..NFFTEDEyVS...SSEKGL.NK.KCRGR.ANGE----Pr.........mKMRRIFRITH.GRER..QR.V.....KDPDGVLIRYKKILSTYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLVAPEKMAEVGEFEASREKLLDYARRCYKTM--DEQTHAKVQAMKKSHKLLPISY................................................................................
A0A2I4CJY3_9TELE/83-157              ..........................................................................FILVSNLRTHLYVSLEKNAWLQKRIEELEE.......ERNFL..RCQLD..RF..V..VSM.RN-......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------pdvgefcgdaqrgvkiqpagspsppsp.....................................................
A0A2D0RG94_ICTPU/65-168              .........................................................................y-LLITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................D.SN.GNDARSFSWRRRR.E..-NERDQQAEV..QRSASRQ.S-...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------fpqrpaqqpptnakvmstssg...........................................................
G3P462_GASAC/167-345                 ...........................................................rtrrstavpgeqivs------------------------------.......-----..-----..--..-..---.---......................................-.--.------SCQQKES.V..KQEFHLEEDK..YYTEDEY.DS...SAEKGS.KK.KGR--.GRGNAEPRM...........KMRRIFRITH.GRER..QR.V.....KDPEGVMIRYKKILATYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLMAPEKVAEVGEFEASKEKLLDYARRCYKTM--DDQTHAKVQTMKKTHKLLPISY................................................................................
F6RJW0_ORNAN/56-105                  .........................................................................l-ALMNGVKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RLD......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------a...............................................................................
A0A151MG69_ALLMI/56-237              .........................................................................l-ALMNSMKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.KVD......................................A.--.EDHCRSKQPLRR-.-..-SDATDSRNG..EVTDNDS.VA...SSLSAN.TE.EGSST.ERKKQKQKG..........gVNRRRLIKPK.TRER..QR.V.....KDADGVLCRYKKILNTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAE----------------------------------------------dsllpp..........................................................................
I3K5V9_ORENI/5-231                   .........................................................................t-ALLNKEQEELTFLKEKLEWQKMRIEELEG.......ERDFL..RRQLS..SF..T..KSS.ALK......................................S.ES.HKLTKSSEQPKDQ.P..FNDPFSLKAS..ENSDSSS.AF...SSVSSV.WS.SSSSF.PKKRKQKYKk........khSRAKKPKKEQ.KKLR..QH.V.....QTPNDIVQRCKSPLKTFPRTKTMTKAFQKHGLDRNTVVSTSSVGELAIAVPNVYQELLSNRSSGETVLAFAKRCEAAIQGSDEV--KKQNRNASAIFKRLVY................................................................................
G3P8Y1_GASAC/173-377                 ltnqlasinalfsstqsqailqghshstpntsasgssgngnsatrssmnslsllgesdeyleqdgyleeeemms------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...-----G.ED.LMQGT.INGNRHQF-...........KRRRIFRAP-.-RER..QR.V.....KDAAGVLFRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYAAL--DEETLSRVQALKKNNLLLPISY................................................................................
W5MM13_LEPOC/1-223                   .........................................................................m-LTITKLQCLLESKQERINFLEKQVEDLQQ.......DRKFL..RSQIE..NL..T..SAK.SI-......................................T.ED.SKPGKSLYSESKP.R..KRSRTASSSS..SFSNDSG.SD...ISLTTV.SS.GTSND.GKKKRHH--...........KDKRRGKKAK.DYSR..KR.A.....TGVQYVIHRYKQVLSAFNKKKSMSGAFRHYGIDRNTIANTAPIAELHLAAKEMLQVVGLFHPREETLVKYAQKCAVVIENDENLSRKIEQMKATGELLPIT-a...............................................................................
M7ATU1_CHEMY/1-50                    ..........................................................................---MSSMKTQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.KVD......................................A.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------vkd.............................................................................
A0A2I3SHL8_PANTR/20-241              .........................................................................l-ALMNSVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RME......................................A.--.EDHCRMKPGPRRM.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSAS.ERRRQKQKG..........gASRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
M3XI21_LATCH/69-266                  ........................................................................ql--KIASLQNKIEVQKEEIKHLLASVEELKK.......ERDFL..REQLK..IS..I..-SR.LSK......................................G.ES.NQGCTELSNNS--.-..-----LESGS..DGEDSES.MT...S-----.--.SSSDL.PKRQKHS--...........--YRKKKKTR.----..--.K.....IGVQQVVKRYKKALKLYQKYGSMAKAYGYLNVDRNTIVNTAPIAELFLADSNKFEQIGALKPSKETLRQFAARCADAI--DESIKMKIDAMKEMGHLLPIS-v...............................................................................
A0A2I4BK43_9TELE/264-398             ...............................................................eiipgedimsd------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.----T.INTNRHQ-L...........KQRRLFRAP-.-RER..QR.V.....KDAAGVLFRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYIAL--DEETLSRVQALKKNNLLLPISY................................................................................
F1QJT8_DANRE/158-270                 ...............................................................vqpavqptrdt------------------------------.......-----..-----..--..-..---.---......................................A.AL.RLRCETVNSPALT.A..SSSTIVTSQK..NQSTDTS.SD...SSESTD.SS.DSEPT.AKKKKKGKK...........SKRQKKSKTK.MIDI..KR.V.....RTPEDSINRYNKVLQLVRDGLSKAEAY---------------------------------------------------------------------------................................................................................
W5KQ74_ASTMX/220-389                 ..............................................kdfvcsiyeeeddvieeeeylqedgyfe------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.-E...EELSDD.ES.DGKSS.RKGRSNGGHr.........vKRTRVFRIAR.SMER..QR.V.....KDPAGVLLRYNKILVTYQKLKSMSRAFQVHGVDRNTVASTTPIAELLLVAPEKVAEIGEFDSAKEKLLDYARRCYKAL--DEAAHAKVQSLKKSSLLLPISY................................................................................
A0A087XMQ5_POEFO/3-85                ..........................................................................FILISNLRAHLYVSLEKNAWLQKRIEELEE.......ERNFL..RCQLD..RF..I..VSM.RSP......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------dgelflnsvadwcgdpqrtvkvqpasspsppspm..............................................
H2T1A0_TAKRU/55-273                  ..........................................................................FILVSNLRAHLYVALEKNAWLQKRIEELEE.......ERNFL..RCQLD..RF..I..VSM.RSS......................................E.--.GEDARLLQSHSVF.L..IHHNEEEDDD..DEEEDEA.S-...SSEKGL.KK.KGRGR.ANSEPRM--...........KMRRIFRITH.GRER..QR.V.....KDPDGVLIRYKKILTTYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLVAPEKMTEVGEFEASREKLLDYARRCYKTM--DEQTHTKVQAMKKTHKLLPISY................................................................................
A0A0F8BK85_LARCR/82-312              .........................................................................l-LTITKLQCMLESKQERIAALERQVEDLMQ.......DRKFL..RSQIE..NL..T..SNR.SMPtfas..............................pspmA.EA.PKPSKAQHSENKS.R..KRERASCTSS..DSS-DSG.SE...ASDSSE.VS.AASSE.HRRKKHH--...........KDKKKSRKGK.DYSR..KR.A.....TGVQYVIHRYKQVLSAFIKKKSMSEAFRHLGIDRNTIANTASIAELHLAGKDMVPLVGMFRQGEETLVSYAHRCTLVIDTDAELSRKIDQMKASGELLPIS-g...............................................................................
A0A1U8CSL4_MESAU/74-184              ................................................................hqrrppgtli------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
W5U8A3_ICTPU/58-160                  .........................................................................y-LLISNLRAQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FTT.KSQ......................................E.RS.ELQPEVSQQPTSQ.N..TVVRRTSSPV..PMMTRSR.QA...RSQTLK.R-.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------nkkknsvqdee.....................................................................
B5X442_SALSA/239-393                 .....................................sllgeaeefleqdgymneeemisgedvmsegmssggh------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.------PGM...........KRRRVFRIT-.-RER..QR.V.....KDAAGVLFRYKKILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAEMLLVAPEKVAEVGEFDPSKEKLLDYARRCYVAL--DEETLSRVQALKKNNLLLPISY................................................................................
H3C8M9_TETNG/6-179                   .......................drakkrahrkslvfsneplslvgesgeyleqdayleedelisgedvlsdvt------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.INGNRPQV-...........KRRRLYRA--.PRER..QR.V.....KDAAGVLLRYKRILLTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKVAEVGEFDPSKEKLLDYARRCYTAL--DEETLSRVQALKKNNLLLPISY................................................................................
A0A286XTF3_CAVPO/154-375             .........................................................................l-ALMNGVKAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCCMKPGPRRV.E..-GDSRAGAGG..EASDPES.AA...SSLSEA.SE.EGSAS.DRKRQKQKG..........sASRKRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DEETLKKVQALKKSKLLLPITY................................................................................
W5LIG5_ASTMX/213-383                 ........................seslsllgeeedefledgyleeeemmsgedvmsenlalrnmgapgrpsvg------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.-----HPAL...........KRRRVFRIAR.GRER..QR.V.....KDAAGVLFRYKKILVTYQRLKNMSKAFQIHGVDRNTVASTTPIAELLLVAPEKLAEVGEFDPSKEKLLDYARRCYIAL--DPQTLSKVQALKKNNLLLPISY................................................................................
H2LN76_ORYLA/17-244                  ..........................................................................FILVSNLRAHLYVSLEKNSWLQKRIEELEE.......ERNFL..RCQLN..RF..I..VSM.SPE......................................G.PA.QLLAKPSLPHDHP.V..WNDPETPAGL..RTSNPPQ.HL..rSCGEGL.KE.EGPST.ERRRAQDEAe........iaKSLAVLGKTH.HTLT..HK.V.....KDPDGVLIRYKKILTTYQRVRSMSRAFQIHGVDRNTMASTSPIAELLLVAPEKVSEVGEFEASKEKLLDYARRCYKTM--DEETHAKVQSMKKTHKLLPISY................................................................................
A0A0P7UEN8_9TELE/84-308              .........................................................................m-LTITRLQCLLESKQEKINSLEKQIEDLQQ.......DRKFL..RAQIE..NL..T..SSR.SSS......................................AiED.SKPGRSLYCDPKP.R..KRMRATSSSS..SFSSDSG.SE...VSISTA.TS.GTASD.VKKKKHH--...........KEKKRGRKSK.DYSR..KR.A.....TGVQYVIHRYKQVLSAFNKKKSMSGAFRHYGIDRNTIANTAPIAELYLAAKETLPQVGLFHPREETLVKYAQKCAVVIESDEVLSRKIELMKATGELLPIT-a...............................................................................
H2M2I7_ORYLA/40-142                  .......................................................................qlv---TKQQQQQIKKLTEKIQRQEELIKELSA.......EKDFL..KEQLA..KH..P..PQA.STN......................................-.DI.MLHGKQQKTSQVQsS..SSASTSSSSS..DSSDSSC.SN...SSSDSS.SE.SSSSD.EEKKK----...........----------.----..--.-.....------------------------------------------------------------------------------------------------------................................................................................
S7NJX5_MYOBR/1-48                    .........................................................................m----SGVRAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------v...............................................................................
E7FFX2_DANRE/437-570                 .........................................................................m-LTITKLQCLLESKQERIEALERQVQDLME.......DRKFL..RAQIE..NL..T..GAR.LIS......................................V.--.PEASTSLISESRS.R..KRRRKSSSSS..YINDECF.TD...ESSSTS.SS.EESSS.MRKKRRHKK...........KRKREKQESQ.TRSN..SK.I.....QANTKANHRY--------------------------------------------------------------------------------------------vp..............................................................................
M7ATU1_CHEMY/45-148                  .......................................................................vda------------------------------.......-----..-----..--..-..---.---......................................-.--.-------------.-..----------..-------.--...------.--.-----.---------...........----------.----..--.V.....KDADGVLCRYKKILNTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
F7AW45_HORSE/54-275                  .........................................................................v-ALMNGVRAQLHMALERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RMD......................................A.--.EDHCRVKPGPRRV.E..-GDSRGGAGG..EASDPES.AA...SSLSGA.SE.EGSNV.ERKRQKQKG..........gAGRRRFGKPK.ARER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKSKLLLPITY................................................................................
H2SP97_TAKRU/61-156                  .........................................................................y-MVITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSH......................................G.QE.PVGYEPRRFTWRA.R..REDER-PAEQ..QKS-NSQ.HF...S-----.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------srpfiqrrpgpp....................................................................
A0A1S3GMF5_DIPOR/56-278              .........................................................................p-VLMTAMRAQLHLAVERNSWLQKRIEDLEE.......ERDFL..RCQLD..KF..I..SSA.RVD......................................A.--.EDHGRVKPGARR-.V..DGDSRAAVGG..EASDPES.AA...SSLSGA.SE.EGGSG.SERKRQKQKg.........sAGRRCFGKPK.VRER..QR.V.....KDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGVFDPSKERLLEYSRRCFLAL--DDETLKKVQALKKNKLLLPITY................................................................................
H2M7M4_ORYLA/65-163                  .........................................................................y-MMITNLRTQLQISLEKNSWLQKRIEDLEE.......ERDFL..RCQLD..RF..I..FST.KSQ......................................G.--.QEQCRSQYSNGYE.SrrFNWKLRREGY..RPSEQQK.TE...S-----.--.-----.---------...........----------.----..--.-.....------------------------------------------------------------------------------------------------------shfpqrqfmprrs...................................................................
#=GC seq_cons                        .........................................................................h.hhhsthpspLphthE+.paLp++IE-Lcc.......ERcFL..RsQL-..ph..h...st.p.p......................................t.......sp.....tp......ttth..ttt..p.ss.ps.s....up.ss..tp.tsts...pp+ppt.............tt++hhttsp..ppR..pR.l.....+ssssVlhRYK+lL.sap+h+sMo+AFphhtVDRNTlA.TssIAELhlsuPEphtplhthcsppEpLhpaupRChhsh..Dpphht+lpshKppthLLPIs.................................................................................
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