GenomeNet

Database: Pfam
Entry: CIA30
LinkDB: CIA30
Original site: CIA30 
#=GF ID   CIA30
#=GF AC   PF08547.12
#=GF DE   Complex I intermediate-associated protein 30 (CIA30)
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Wood V;0000-0001-6330-7526
#=GF SE   manual
#=GF GA   19.70 19.00;
#=GF TC   19.70 19.00;
#=GF NC   19.60 18.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11935339
#=GF RT   CIA30 complex I assembly factor: a candidate for human complex I
#=GF RT   deficiency?. 
#=GF RA   Janssen R, Smeitink J, Smeets R, van Den Heuvel L; 
#=GF RL   Hum Genet 2002;110:264-270.
#=GF RN   [2]
#=GF RM   1518044
#=GF RT   Sequences of 20 subunits of NADH:ubiquinone oxidoreductase from
#=GF RT   bovine heart mitochondria. Application of a novel strategy for
#=GF RT   sequencing proteins using the polymerase chain reaction. 
#=GF RA   Walker JE, Arizmendi JM, Dupuis A, Fearnley IM, Finel M, Medd
#=GF RA   SM, Pilkington SJ, Runswick MJ, Skehel JM; 
#=GF RL   J Mol Biol 1992;226:1051-1072.
#=GF DR   INTERPRO; IPR013857;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This protein is associated with mitochondrial Complex I
#=GF CC   intermediate-associated protein 30 (CIA30) in human and mouse.
#=GF CC   The family is also present in Schizosaccharomyces pombe which
#=GF CC   does not contain the NADH dehydrogenase component of complex I,
#=GF CC   or many of the other essential subunits.    This means it is
#=GF CC   possible that this family of protein may not be directly
#=GF CC   involved in oxidative phosphorylation [1][2].
#=GF SQ   2618
#=GS A0A1Z9LNN3_9CYAN/9-179      AC A0A1Z9LNN3.1
#=GS A0A0J1JF63_9GAMM/2-153      AC A0A0J1JF63.1
#=GS N1JMX4_BLUG1/8-179          AC N1JMX4.1
#=GS A0A1Y2FRQ9_9BASI/40-220     AC A0A1Y2FRQ9.1
#=GS I2FRW2_USTH4/18-101         AC I2FRW2.1
#=GS A0A1D5UEK1_WHEAT/248-419    AC A0A1D5UEK1.1
#=GS A0A1R3RQS2_ASPC5/14-186     AC A0A1R3RQS2.1
#=GS T0NP60_CAMFR/113-244        AC T0NP60.1
#=GS A0A178ZLB9_9EURO/222-391    AC A0A178ZLB9.1
#=GS A0A1E5VTE3_9POAL/557-742    AC A0A1E5VTE3.1
#=GS A0A0B0MTJ6_GOSAR/266-438    AC A0A0B0MTJ6.1
#=GS A0A091F4Y1_CORBR/102-273    AC A0A091F4Y1.1
#=GS J4G795_9APHY/39-214         AC J4G795.1
#=GS E3QZY6_COLGM/15-195         AC E3QZY6.1
#=GS A0A2C9LGQ6_BIOGL/14-123     AC A0A2C9LGQ6.1
#=GS A0A1H9GFC9_9GAMM/1-177      AC A0A1H9GFC9.1
#=GS A0A135SE25_9PEZI/43-234     AC A0A135SE25.1
#=GS A0A1Z4NLC6_9CYAN/153-319    AC A0A1Z4NLC6.1
#=GS A0A1V6P2X9_9EURO/563-735    AC A0A1V6P2X9.1
#=GS A0A1Y2HU07_9FUNG/161-242    AC A0A1Y2HU07.1
#=GS A0A2D3UR49_9PEZI/45-248     AC A0A2D3UR49.1
#=GS A0A2C5YF60_9HYPO/8-136      AC A0A2C5YF60.1
#=GS A0A094HPL4_9PEZI/42-225     AC A0A094HPL4.1
#=GS B1XKW5_SYNP2/122-288        AC B1XKW5.1
#=GS E3M087_CAERE/136-309        AC E3M087.1
#=GS C5MEG7_CANTT/29-202         AC C5MEG7.1
#=GS A0A225A904_9EURO/8-202      AC A0A225A904.1
#=GS K8NNC7_AFIFE/18-171         AC K8NNC7.1
#=GS A0A090LQE5_STRRB/130-313    AC A0A090LQE5.1
#=GS A0A1Y2FQ99_9ASCO/3-175      AC A0A1Y2FQ99.1
#=GS A0A0C3HRX9_9VIBR/27-199     AC A0A0C3HRX9.1
#=GS A0A1V8UQM1_9PEZI/44-233     AC A0A1V8UQM1.1
#=GS A0A0S7DHG9_9EURO/46-179     AC A0A0S7DHG9.1
#=GS A0A1J6KW13_NICAT/283-438    AC A0A1J6KW13.1
#=GS A0A1Z5TCI1_HORWE/10-188     AC A0A1Z5TCI1.1
#=GS R1E8P8_EMIHU/23-177         AC R1E8P8.1
#=GS I1NYT5_ORYGL/247-419        AC I1NYT5.1
#=GS A0A0K9PQQ7_ZOSMR/252-426    AC A0A0K9PQQ7.1
#=GS A0A1Y1YCB6_9FUNG/10-179     AC A0A1Y1YCB6.1
#=GS A0A1L9UKN6_9EURO/13-184     AC A0A1L9UKN6.1
#=GS A0A0S7DHG9_9EURO/211-278    AC A0A0S7DHG9.1
#=GS W9WRH1_9EURO/44-232         AC W9WRH1.1
#=GS A0A1X7RG89_ZYMTR/13-192     AC A0A1X7RG89.1
#=GS A0A2C5XKV3_9HYPO/10-178     AC A0A2C5XKV3.1
#=GS E1BZH1_CHICK/104-277        AC E1BZH1.1
#=GS A0A1B7NE01_9HOMO/41-229     AC A0A1B7NE01.1
#=GS A0A182N139_9DIPT/117-292    AC A0A182N139.1
#=GS A0A0L1ISD3_ASPNO/196-268    AC A0A0L1ISD3.1
#=GS A0A066WGU2_9BASI/17-120     AC A0A066WGU2.1
#=GS A0A0S6XKP2_9FUNG/44-219     AC A0A0S6XKP2.1
#=GS B7QFX2_IXOSC/91-264         AC B7QFX2.1
#=GS A0A1V0KY15_9GAMM/2-153      AC A0A1V0KY15.1
#=GS A0A1L9P1P7_9RHOB/21-166     AC A0A1L9P1P7.1
#=GS A0A0E0NC66_ORYRU/301-363    AC A0A0E0NC66.1
#=GS A0A076HCY8_9SYNE/9-179      AC A0A076HCY8.1
#=GS C8VAT4_EMENI/46-169         AC C8VAT4.1
#=GS A0A1V6TS95_9EURO/8-189      AC A0A1V6TS95.1
#=GS A0A0V0TKX4_9BILA/123-305    AC A0A0V0TKX4.1
#=GS A0A0J8R8B5_COCIT/45-177     AC A0A0J8R8B5.1
#=GS A0A182XYD1_ANOST/5-103      AC A0A182XYD1.1
#=GS A0A287XFU6_HORVV/114-275    AC A0A287XFU6.1
#=GS A0A1Q9DID1_SYMMI/92-257     AC A0A1Q9DID1.1
#=GS M7BNX5_CHEMY/47-220         AC M7BNX5.1
#=GS I1Q521_ORYGL/365-491        AC I1Q521.1
#=GS A0A0V0RQ41_9BILA/116-298    AC A0A0V0RQ41.1
#=GS A0A0K8LBE0_9EURO/211-278    AC A0A0K8LBE0.1
#=GS A6QUW9_AJECN/196-273        AC A6QUW9.1
#=GS A0A0K9Q5Y0_ZOSMR/35-216     AC A0A0K9Q5Y0.1
#=GS M5GG28_DACPD/37-214         AC M5GG28.1
#=GS A1SWJ1_PSYIN/12-163         AC A1SWJ1.1
#=GS I1GKB1_BRADI/363-492        AC I1GKB1.1
#=GS A0A1E1KHL9_9HELO/43-236     AC A0A1E1KHL9.1
#=GS C4WV72_ACYPI/36-197         AC C4WV72.1
#=GS A0A1I0B2L7_THASX/20-169     AC A0A1I0B2L7.1
#=GS A0A072P9C2_9EURO/4-178      AC A0A072P9C2.1
#=GS A0A0P1BWF2_9CYAN/184-350    AC A0A0P1BWF2.1
#=GS G1KC72_ANOCA/56-229         AC G1KC72.1
#=GS A0A0S8F4Y1_9GAMM/2-146      AC A0A0S8F4Y1.1
#=GS A0A1V6UFN1_9EURO/207-274    AC A0A1V6UFN1.1
#=GS M7US32_BOTF1/3-172          AC M7US32.1
#=GS D7KFE6_ARALL/35-218         AC D7KFE6.1
#=GS A0A084QAU6_STAC4/5-183      AC A0A084QAU6.1
#=GS X0J2V9_FUSOX/43-224         AC X0J2V9.1
#=GS K9WTJ8_9NOST/185-351        AC K9WTJ8.1
#=GS B6QT76_TALMQ/217-276        AC B6QT76.1
#=GS A0A1E7FZY9_9STRA/15-219     AC A0A1E7FZY9.1
#=GS C5FZF6_ARTOC/214-286        AC C5FZF6.1
#=GS A0A177E1X7_ALTAL/43-218     AC A0A177E1X7.1
#=GS A0A1S2XG98_CICAR/225-391    AC A0A1S2XG98.1
#=GS C7Z5E7_NECH7/7-176          AC C7Z5E7.1
#=GS A0A094FHK5_9PEZI/1-86       AC A0A094FHK5.1
#=GS D0L0M3_HALNC/14-164         AC D0L0M3.1
#=GS A0A1I8MQM0_MUSDO/103-278    AC A0A1I8MQM0.1
#=GS A0A1I5C1C7_9FLAO/7-157      AC A0A1I5C1C7.1
#=GS W6UK33_ECHGR/272-424        AC W6UK33.1
#=GS A0A183NI52_9TREM/31-214     AC A0A183NI52.1
#=GS F2CYP1_HORVV/35-220         AC F2CYP1.1
#=GS E6R264_CRYGW/164-245        AC E6R264.1
#=GS A0A0P1BFW6_9BASI/59-184     AC A0A0P1BFW6.1
#=GS A0A286U939_9HOMO/38-234     AC A0A286U939.1
#=GS K2HKG2_9RHOB/7-156          AC K2HKG2.1
#=GS K9Z313_CYAAP/135-298        AC K9Z313.1
#=GS N1Q218_DOTSN/14-191         AC N1Q218.1
#=GS A0A0F2RVR0_9RHOB/24-169     AC A0A0F2RVR0.1
#=GS A0A0R0IR93_SOYBN/138-310    AC A0A0R0IR93.1
#=GS A0A0R0IYX4_SOYBN/264-411    AC A0A0R0IYX4.1
#=GS Q29BT8_DROPS/131-306        AC Q29BT8.2
#=GS A0A1U8J503_GOSHI/209-381    AC A0A1U8J503.1
#=GS F2UEK1_SALR5/307-390        AC F2UEK1.1
#=GS A0A2H3FY56_9HELO/15-164     AC A0A2H3FY56.1
#=GS A0A1E7FIJ3_9STRA/40-193     AC A0A1E7FIJ3.1
#=GS D8TR43_VOLCA/256-349        AC D8TR43.1
#=GS A0A0W0FJ69_9AGAR/40-227     AC A0A0W0FJ69.1
#=GS W9I8K3_FUSOX/43-224         AC W9I8K3.1
#=GS A0A287HCQ6_HORVV/1-153      AC A0A287HCQ6.1
#=GS A0A0J6Y124_COCIT/45-177     AC A0A0J6Y124.1
#=GS A0A0D7AL89_9AGAR/3-175      AC A0A0D7AL89.1
#=GS A0A2B4RKJ2_STYPI/42-209     AC A0A2B4RKJ2.1
#=GS M2UUF2_COCH5/8-176          AC M2UUF2.1
#=GS A0A1A9UQ72_GLOAU/95-270     AC A0A1A9UQ72.1
#=GS A0A0M8NWE4_9EURO/263-331    AC A0A0M8NWE4.1
#=GS F8GIQ2_NITSI/41-189         AC F8GIQ2.1
#=GS Q3J7P8_NITOC/29-181         AC Q3J7P8.1
#=GS M2X7Y9_GALSU/63-224         AC M2X7Y9.1
#=GS K0S810_THAOC/155-313        AC K0S810.1
#=GS A0A200QP11_9MAGN/9-197      AC A0A200QP11.1
#=GS A0A094ZAK8_SCHHA/54-223     AC A0A094ZAK8.1
#=GS A0A067KWS0_JATCU/35-216     AC A0A067KWS0.1
#=GS A0A0C9UEC4_9HOMO/2-114      AC A0A0C9UEC4.1
#=GS A0A0A2KU09_PENIT/207-274    AC A0A0A2KU09.1
#=GS A0A1L9SIX8_9EURO/2-171      AC A0A1L9SIX8.1
#=GS A0A160DYM3_9GAMM/462-614    AC A0A160DYM3.1
#=GS D8G2R6_9CYAN/181-347        AC D8G2R6.1
#=GS Q21ZL2_RHOFT/20-173         AC Q21ZL2.1
#=GS A0A168BK81_CORDF/20-192     AC A0A168BK81.1
#=GS A0A074XUV6_AURPU/37-212     AC A0A074XUV6.1
#=GS A1WWI6_HALHL/14-166         AC A1WWI6.1
#=GS A0A1G9EK10_9GAMM/5-157      AC A0A1G9EK10.1
#=GS A0A0G4NV98_PENCA/4-176      AC A0A0G4NV98.1
#=GS A0A1Z4M1A8_9CYAN/178-344    AC A0A1Z4M1A8.1
#=GS M4EB21_BRARP/35-133         AC M4EB21.1
#=GS A0A251PUA3_PRUPE/303-473    AC A0A251PUA3.1
#=GS A0A2K1IDM6_PHYPA/326-480    AC A0A2K1IDM6.1
#=GS W6ZPJ4_COCMI/8-176          AC W6ZPJ4.1
#=GS A0A0E9NGV6_9ASCO/33-203     AC A0A0E9NGV6.1
#=GS A0A0G4P1P0_PENCA/207-274    AC A0A0G4P1P0.1
#=GS Q15TC3_PSEA6/2-153          AC Q15TC3.1
#=GS A0A182UHD6_9DIPT/120-295    AC A0A182UHD6.1
#=GS K9STU8_9SYNE/86-251         AC K9STU8.1
#=GS A0A1I7XND0_HETBA/4-76       AC A0A1I7XND0.1
#=GS M1F6I8_9ALTE/27-180         AC M1F6I8.1
#=GS Q0V6I3_PHANO/43-218         AC Q0V6I3.1
#=GS A0A0N0NL61_9EURO/11-178     AC A0A0N0NL61.1
#=GS A0A0G3UZ20_9ACTN/43-196     AC A0A0G3UZ20.1
#=GS A0A2I4G310_9ROSI/306-464    AC A0A2I4G310.1
#=GS W3XHK6_PESFW/43-220         AC W3XHK6.1
#=GS M7WTF7_RHOT1/8-207          AC M7WTF7.1
#=GS A0A1I1L3N7_9BURK/440-569    AC A0A1I1L3N7.1
#=GS A0A2K2AQK7_POPTR/7-179      AC A0A2K2AQK7.1
#=GS A0A269PSJ6_9GAMM/1-125      AC A0A269PSJ6.1
#=GS A0A2H3ILT8_9EURO/216-276    AC A0A2H3ILT8.1
#=GS A0A195EX81_9HYME/14-183     AC A0A195EX81.1
#=GS A0A1H5J8S1_9FLAO/20-170     AC A0A1H5J8S1.1
#=GS A0A0N7KEZ7_ORYSJ/13-185     AC A0A0N7KEZ7.1
#=GS H2M0V2_ORYLA/96-255         AC H2M0V2.1
#=GS A0A218WK81_PUNGR/167-339    AC A0A218WK81.1
#=GS I3IFT9_9GAMM/23-177         AC I3IFT9.1
#=GS A0A078IE30_BRANA/35-225     AC A0A078IE30.1
#=GS M1UXZ9_CYAM1/257-427        AC M1UXZ9.1
#=GS W5N6U8_LEPOC/97-270         AC W5N6U8.1
#=GS A0A026WF33_OOCBI/96-270     AC A0A026WF33.1
#=GS A0A183WYI1_TRIRE/25-119     AC A0A183WYI1.1
#=GS A0A0X8WXL6_9CYAN/8-173      AC A0A0X8WXL6.1
#=GS V4MJE3_EUTSA/261-433        AC V4MJE3.1
#=GS B4RF48_PHEZH/425-554        AC B4RF48.1
#=GS A0A0S2F8S1_9GAMM/461-592    AC A0A0S2F8S1.1
#=GS S7PYZ3_GLOTA/36-220         AC S7PYZ3.1
#=GS A0A1J6IX64_NICAT/262-433    AC A0A1J6IX64.1
#=GS A0A084RJ76_STACH/30-205     AC A0A084RJ76.1
#=GS A0A011PW93_9PROT/6-159      AC A0A011PW93.1
#=GS K1WWZ9_MARBU/20-210         AC K1WWZ9.1
#=GS A0A257DDP1_9BURK/1-146      AC A0A257DDP1.1
#=GS A5ABR3_ASPNC/46-216         AC A5ABR3.1
#=GS A0A1V6NYR3_9EURO/43-173     AC A0A1V6NYR3.1
#=GS A0A074YT27_9PEZI/25-194     AC A0A074YT27.1
#=GS A0A1Q9CSU8_SYMMI/1241-1400  AC A0A1Q9CSU8.1
#=GS A0A0D9WJL1_9ORYZ/155-247    AC A0A0D9WJL1.1
#=GS I3KU85_ORENI/105-278        AC I3KU85.1
#=GS A0A1V2LA88_CYBFA/9-178      AC A0A1V2LA88.1
#=GS A0A1K2IFG3_9FLAO/20-170     AC A0A1K2IFG3.1
#=GS A0A1Q9E3A7_SYMMI/751-901    AC A0A1Q9E3A7.1
#=GS A0A1D7XUN5_9FLAO/14-164     AC A0A1D7XUN5.1
#=GS A0A1E7FLK0_9STRA/320-454    AC A0A1E7FLK0.1
#=GS A0A1I7T6V5_9PELO/136-309    AC A0A1I7T6V5.1
#=GS A0A1H9RI21_9FLAO/20-170     AC A0A1H9RI21.1
#=GS K9GPL5_PEND2/190-258        AC K9GPL5.1
#=GS E9HNE0_DAPPU/93-266         AC E9HNE0.1
#=GS A0A0U1LTY9_TALIS/41-136     AC A0A0U1LTY9.1
#=GS A0A1H7Q5E7_9FLAO/8-158      AC A0A1H7Q5E7.1
#=GS CIA30_ARATH/35-218          AC Q9LQI7.2
#=GS C1H538_PARBA/45-175         AC C1H538.1
#=GS A0A1Y1USW1_9TREE/73-289     AC A0A1Y1USW1.1
#=GS B3EKW9_CHLPB/9-161          AC B3EKW9.1
#=GS A0A1M4UQ78_9FLAO/18-169     AC A0A1M4UQ78.1
#=GS A0A285TBP8_9RHOB/31-175     AC A0A285TBP8.1
#=GS A3GFG1_PICST/31-204         AC A3GFG1.1
#=GS A0A1I6GY94_9ALTE/12-165     AC A0A1I6GY94.1
#=GS I2CYE1_MACMU/125-298        AC I2CYE1.1
#=GS A0A165EKY3_EXIGL/15-194     AC A0A165EKY3.1
#=GS A3PCI0_PROM0/6-176          AC A3PCI0.1
#=GS A0A1G9IJZ9_9FLAO/22-172     AC A0A1G9IJZ9.1
#=GS A0A1B0BNY6_9MUSC/95-270     AC A0A1B0BNY6.1
#=GS A0A0K8P5E5_IDESA/11-164     AC A0A0K8P5E5.1
#=GS A0A1P8APK0_ARATH/35-137     AC A0A1P8APK0.1
#=GS A0A091X835_OPIHO/104-279    AC A0A091X835.1
#=GS W9WSQ2_9EURO/21-174         AC W9WSQ2.1
#=GS A0A2C5XHH9_9HYPO/27-133     AC A0A2C5XHH9.1
#=GS N4V4C3_COLOR/12-163         AC N4V4C3.1
#=GS A0A1E2WPK9_9NOSO/185-351    AC A0A1E2WPK9.1
#=GS A0A1G5UTF1_9SPHN/479-591    AC A0A1G5UTF1.1
#=GS W8VRU9_9FLAO/3-154          AC W8VRU9.1
#=GS A0A0L7QTP0_9HYME/84-258     AC A0A0L7QTP0.1
#=GS A0A2H3EDR7_9HELO/27-184     AC A0A2H3EDR7.1
#=GS A0A2I0MQ12_COLLI/104-277    AC A0A2I0MQ12.1
#=GS A0A0K0FU01_9BILA/128-301    AC A0A0K0FU01.1
#=GS A0A1U7WG62_NICSY/285-440    AC A0A1U7WG62.1
#=GS E9EIZ3_METAQ/11-178         AC E9EIZ3.1
#=GS A0A180ERG5_9BACT/9-161      AC A0A180ERG5.1
#=GS A0A158RCQ6_THECL/866-1039   AC A0A158RCQ6.1
#=GS A7EFA8_SCLS1/19-200         AC A7EFA8.1
#=GS A0A0J0XGK3_9TREE/37-238     AC A0A0J0XGK3.1
#=GS A0A2H3XB61_PHODC/35-218     AC A0A2H3XB61.1
#=GS A0A151MVB0_ALLMI/5-146      AC A0A151MVB0.1
#=GS A0A091BLI3_9GAMM/1-154      AC A0A091BLI3.1
#=GS A0A1C1X0D2_9PEZI/42-226     AC A0A1C1X0D2.1
#=GS A0A1L9PXC5_ASPVE/24-175     AC A0A1L9PXC5.1
#=GS I1NX36_ORYGL/314-442        AC I1NX36.1
#=GS A0A1M5B0I1_9FLAO/22-172     AC A0A1M5B0I1.1
#=GS D8TYK1_VOLCA/21-198         AC D8TYK1.1
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V4MTE4_EUTSA/48-240                    ..................................................................