GenomeNet

Database: Pfam
Entry: Chordopox_G2
LinkDB: Chordopox_G2
Original site: Chordopox_G2 
#=GF ID   Chordopox_G2
#=GF AC   PF05796.12
#=GF DE   Chordopoxvirus protein G2
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_7672 (release 8.0)
#=GF GA   25.00 25.00;
#=GF TC   202.70 202.50;
#=GF NC   20.50 20.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   2024483
#=GF RT   Genetic and molecular biological characterization of a vaccinia
#=GF RT   virus gene which renders the virus dependent on
#=GF RT   isatin-beta-thiosemicarbazone (IBT). 
#=GF RA   Meis RJ, Condit RC; 
#=GF RL   Virology 1991;182:442-454.
#=GF DR   INTERPRO; IPR008446;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several Chordopoxvirus
#=GF CC   isatin-beta-thiosemicarbazone dependent protein (protein G2)
#=GF CC   sequences. Inactivation of the gene coding for this protein
#=GF CC   renders the virus dependent upon isatin-beta-thiosemicarbazone
#=GF CC   (IBT) for growth [1].
#=GF SQ   31
#=GS Q6VZP2_CNPV/1-220       AC Q6VZP2.1
#=GS G2_VAR67/1-214          AC P32992.1
#=GS A0A068EF86_9POXV/1-221  AC A0A068EF86.1
#=GS Q070H7_CPRVZ/1-216      AC Q070H7.1
#=GS U3UBG7_9POXV/1-215      AC U3UBG7.1
#=GS A0A0A7M9Q6_9POXV/1-210  AC A0A0A7M9Q6.1
#=GS A0A223FMQ6_9POXV/1-214  AC A0A223FMQ6.1
#=GS Q8V3P5_SWPV1/1-215      AC Q8V3P5.1
#=GS Q0NPC8_9POXV/1-214      AC Q0NPC8.1
#=GS Q08FU1_DPV83/1-214      AC Q08FU1.1
#=GS Q98226_MCV1/1-238       AC Q98226.1
#=GS G2_VACCW/1-214          AC P68456.1
#=GS Q9J5D3_FOWPN/1-221      AC Q9J5D3.1
#=GS G3EID7_9POXV/1-214      AC G3EID7.1
#=GS A0A1Z3GCW1_9POXV/1-209  AC A0A1Z3GCW1.1
#=GS A0A1B1MRC2_9POXV/1-216  AC A0A1B1MRC2.1
#=GS Q6TVT1_ORFSA/1-210      AC Q6TVT1.1
#=GS Q8V508_COWPX/1-214      AC Q8V508.1
#=GS A0A0M3PB54_9POXV/1-221  AC A0A0M3PB54.1
#=GS Q6TVE9_9POXV/1-210      AC Q6TVE9.1
#=GS D3IZI6_9POXV/1-210      AC D3IZI6.1
#=GS Q9Q924_RFVKA/1-215      AC Q9Q924.1
#=GS G2_VACCC/1-214          AC P68457.1
#=GS A0A097IVR3_9POXV/1-216  AC A0A097IVR3.1
#=GS A0A220T6C0_9POXV/1-215  AC A0A220T6C0.1
#=GS Q77GD8_LSDVN/1-214      AC Q77GD8.1
#=GS A0A0G3G012_RACVI/1-214  AC A0A0G3G012.1
#=GS Q9Q8P9_MYXVL/1-215      AC Q9Q8P9.1
#=GS A9J1N0_VACCA/1-214      AC A9J1N0.1
#=GS Q6TUW1_YMTV5/1-215      AC Q6TUW1.1
#=GS A0A0K1LD81_9POXV/1-214  AC A0A0K1LD81.1
Q6VZP2_CNPV/1-220                  MSFRELIYYNLLKYLVSGDTAYMEKFVSLCDSFGIDRVKMLSKFYNSRKTKLITNAL.KCNT.YLDELELSYPDDIIKDLVTLKLNKFTKTIKRSYKLPNRGSGIAII.YDNTVKY-NVDDEILSYLKLKYLPSIYTYFK.--ED.TLSTEDipr................dsvILIFDQDSISYFTYISCKkIVSNTDIKITVTEDCINKLLDEKNKDLLDSVFANRS.nNVLSNTLNEIYSA-v.
G2_VAR67/1-214                     MPFRDLILFNLSKFLLTEDKESLEIVSSLCRGFEISYDDLITYFPDRKYHKYIYKVF.EHVD.LSEELSMEFHDTTLRDLVYLKLYKYSKCIRPCYKLGDNLKGIVVI.KDRNIYIREANDDLIEYLLKEYTPQIYTYSN.EHV-.PIAGSK......................LILCGFSQVTFMAYTTSH.ITTNKKVDVLVSKKCIDKLVDPINYQILQNLFDKGS..GTINKILRKIFYSV..
A0A068EF86_9POXV/1-221             MSFRTLISYNLLKYLVSGDEEYMEKFISLCNSFNVDRVKVLTKYYTSKNTKLISKAL.NCNT.YLKEIELSYPDNILKELVTIKLSKFTKTIKRSYKLPNEGIGIIVI.SGNEIKY-NADNSTVSYCKLKYIPSIYRYTE.-YPD.DIKTEDipk................esiVLIFGKDYLDYFTYMLAKkVLSNKDIKIKVTEQCIDHLLKESNTDMLDTVFSNKT.nNIISNTLNDIYLSL..
Q070H7_CPRVZ/1-216                 MEFG---LFHLAKFLLTEDEEALRQFNGVCAYLQRPKHEVLKDFYCARQSRRITRAL.NCAD.VPAEVALEFPPDLARQLVGLRLRGFRCVVRRSAWLPADAAGEALVaADGRVYHRRCNPAMLAFVRRRYRRLGREFAE.-AGD.ALPAEPg...................glAIVCGRADVSLYEWICRDaLRTNVDAEVVVTEGCIEKVLS--NTKLTSKLLATHHrrNAVHRSLKTIYD--ry
U3UBG7_9POXV/1-215                 MPFRELILFHLTRFLLSGDESSLAEFSSLCQGFQVDARAVVEGLGERRFSRLAAQAA.ACRV.CLPEVTLSFPEDALREVLRLRLSRFSRVVRATARLDPAMRGVAVV.AGREVSVRDADERMMEFLEAEYDPELYRYSA.ERVTrVKTGAR......................ILACGVARVSFLAYAAAN.VVVNRDAAVVVTERCLDGLLRPENRHVLQGLFARGT..G-VNAALRRIFYFL..
A0A0A7M9Q6_9POXV/1-210             MSFRELILFHAAAHVVTGDPEAPRHAASLCAGFGVDFSAAFGEF--ARRYPRTAAAI.ERAD.LLPQTDMAFPTDALRAMVRLRLQASGLQVKAARALTPAMHGAAVV.DGCAVRVFRANDALLEFLVARFDPAVYRYVGvRAPS.VRRGSR......................VFVCAGESVSFIAAHESR.IVANRPMRVVVTDACVARVLERGAAD----VFDRGS..SVLLRALREIFYRL..
A0A223FMQ6_9POXV/1-214             MPFRDLILFNLSKFLLTEDIKSLELVSSLCRGFEISYDQLISYFPERKYHKHISKVF.EIAE.LTSEFDIEFPKTAFYDLIYLRLYKYSRSIRPCYKLDASMKGIVII.KDRNIFIREANDELLEYLFKEYNPQIYSYSV.ERT-.DIAGSK......................VILCGFSEVTFMAYTTSH.ITTNQKVDVVVTKKCINSLIDNDNYQIVKDLFDKGT..GTINKILRKIFYS-f.
Q8V3P5_SWPV1/1-215                 MPFRDLILFHLAKILLTENKDSIKTVLSLCRGFNIDLNELIVEHFGKHHLKKFSQLL.CIDS.LLPELSICFPDNIIHELIHLRLCKFYKTVKPSYKLTTDMKGIVFV.KNRTVYVLNTNDPLIDFMFKEYNPCIYTYTI.GKPD.NLSGYK......................IILCGYDKITFFTYLVTN.ITSNKKIDVIVTEKCLISLLQPENVHLLKQVFNNGH..DRINKVLKHIYYSI..
Q0NPC8_9POXV/1-214                 MSFRDLILFNLSKFLLTEDEESLEIVSSLCRGFEISYDDLITYFPDRKYHKYIYKVF.EHVD.LSEELSMEFHDTTLRDLVYLRLYKYSKCIRPCYKLGDNLKGIVVI.KDRNIYIREANDDLIEYLLKEYTPQIYTYSN.EHV-.PIAGSK......................LILCGFSQVTFMAYTTSH.ITTNKKVDVLVSKKCIDELVDPINYQILQNLFDKGS..GTINKILRKIFYSV..
Q08FU1_DPV83/1-214                 MPFRDIILFYLLKYLLTENHYSMRMIISLCRVYDIKIEDLIVSALSKKYLRKFSKIL.SYPDvLLPEISICFPENIIHELLLLRVQKFSKSIRASYRLTKNMKGIVIV.KNRYLFVVHANDDLLNYLFKEYNPQLYIYDI.GKPS.DVCGSK......................MILCGYSKIKFYTSLVTN.IITNQKIDIVVTEKCIELLAQ--NEQLVKDLFDKSN..DKINRLLRQVFYSV..
Q98226_MCV1/1-238                  MSFRELILYHLVRYLATENDAFLVQFVSLCRSFSVDVPALLARFSTPRHARLLARAL.NCKQ.YTEELALEFPPDALRELLRLKLRRCTPRVRRAARLDARARGAALV.AGREVAVRAANEELLTYLVRTYNPALYRYRR.AGAR.SYTGAGagagtgdpveapglcapagapvLVVCGRSRIPFFAYAAAR.VVSNRDLEVVVTDACVQALLREEHAPLLEAVFRRGA.dTALNRALRSVFRFL..
G2_VACCW/1-214                     MPFRDLILFNLSKFLLTEDEESLEIVSSLCRGFEISYDDLITYFPDRKYHKYISKVF.EHVD.LSEELSMEFHDTTLRDLVYLRLYKYSKCIRPCYKLGDNLKGIVVI.KDRNIYIREANDDLIEYLLKEYTPQIYTYSN.ERV-.PITGSK......................LILCGFSQVTFMAYTTSH.ITTNKKVDVLVSKKCIDELVDPINYQILQNLFDKGS..GTINKILRKIFYSV..
Q9J5D3_FOWPN/1-221                 MSFRTLISYNLLKYLDSGDEAYMEKFISLCNSFNVDRVKVLTKYYNSKNTKLISKAL.NCDT.YLKEIELSYPDNILKELVTIKLGKFTKTIKRSYKLPNEGIGIIVI.NGNEIKY-NADNNTIAYSKLKYIPSIYRYTE.-YPD.GIKTEDipk................esiVLIFGKDYLDYFTYMLAKkVLSNKDIKIKVTDQCIDHLLNESNTDMLDTVFSNKP.nNIISSTLNDIYLSL..
G3EID7_9POXV/1-214                 MPFRDLILFNLSKFLLTDDIKSLELVSSLCRGFEISYDQLISYFPDRKYHKHISKVF.DIRE.LTSELNIEFPETTLYDLIYLRLYKYYKYIKPCYKLDASMKGIVII.KNTNIFIREANDILLEYLFKEYNPQIYSYSV.EH-T.DIIGSK......................IILCGFSKVTFMAYTTSN.ITTNQKIDVVVTKKCIESLSKSDNYQLVKHIFDKGT..GTINKILSKIFYSL..
A0A1Z3GCW1_9POXV/1-209             MSFRELILFHAAAHVVGGDPEAPARAASLCAGFGTNFRALHAEF--ARRYPRTAAAV.DRAA.LLPETGMNFPADALRQLVRMRLEAAALAVKESRALSRTMTGCAVV.DGCCVRVCCANDELLGFLARRYDPNVYRYVKvARPS.VRCGSR......................AFVCSGSKVTFIAAHESR.ITANRPLRVVVTEACVNRVLA-----CPAEMFSCGS..SVLMRALRELFYRL..
A0A1B1MRC2_9POXV/1-216             MSFRELILFNVLKFIIMSDTKSLKTLASLSLAFGSDIVEKNLSKFNKRYYKHILQIT.QCTE.YVPILDLEFDSDVIREIIKLRLLSFNHTIKPLSKLKLTMKGVITV.SRNKVYIYDANDELLEMVMKQYNPSMYNYISsKKPK.VIKGSN......................ILVCGFPKISYFAYSISK.IYVNVPTTVVVTDTCISTLLKDKHCDILKNIFNNGS..GVLNESFKQLFYFL..
Q6TVT1_ORFSA/1-210                 MTFRELILFHAATHVVTGDPEAPRRAASLCHGFGVDFRAIHAEF--ARRYPRTAAAV.ERAQ.PLPEVDAAFPPDARRQVVRLRLEAAALVVKESRALSASMRGVAVV.DGCCVRVCRANDELLEFLARRYDPAVYRYAEvPSPS.VRPGSK......................VFACAGRSVTFAAAHQSR.ITANRPLRVVVTEACVDGVLARGAAE----VFDRGS..GVLPRALREIFYRL..
Q8V508_COWPX/1-214                 MPFRDLILFNLSKFLLTEDEESLEIVSSLCRGFEISYDDLISYFPDRKYHKYISKVF.EHVD.LSEELSMEFHDTTLRDLVYLRLYKYSKYIRPCYKLGDNLKGIVVI.KDRNIYIREANDDLIEYLLKEYTPQIYTYSN.ERV-.PIAGSK......................LILCGFSQVTFMAYTTSH.ITTNKKVDVLVSKKCIDELVDPINYQILQNLFDKGS..GTINKILRKIFYSV..
A0A0M3PB54_9POXV/1-221             MSFKELILYNLVKYLMGGDDIYMKTFISLCGSFGVDRVKVLNRFYNSRNTRLISKIL.KCND.FLNEIELCYPSNILYDLIMLKLDKFTKTIKKSYKLPEYGNGIVII.YNDIILY-KGDNNVIDYIKSRYPSSVYRYIE.QKI-.EIATRDipt................dstVLVFGYKNLEYFTYISSRkILSNTDVKITVTEECINKLLEKPNLKLLDIMFNNKS.nNPLSNTLNEIYLSV..
Q6TVE9_9POXV/1-210                 MSFRELILFHAATHVVTGDPEAPRRAASLCAGFGVSFRAEYGEF--AKRYPRTAAAV.ERAE.LLPETDMVFPPDALRALVRLRLEAAGLSVKASRLLAPAMCGTAVV.DGCSVRVCGANDALLDFLAKRYDPEVYRYVAtAAPS.VRCGSR......................AFVCSGGSVTFVAAHESR.ITANRPLRVVVTDACVTKVLERGAAE----VFERGS..GVLLRALRDMFYRL..
D3IZI6_9POXV/1-210                 MTFRELILFHAATHVVTGDPEAPRRAASLCRGFGVDFRALHAEF--ARRYPRTAAAV.ERAQ.PLPEVEAAFPPDARRRVVRLRLEAAALAVKESRALSASMRGVAVV.DGCCVRVSRANDELLEFLARRYDPAVYRYAEvPVPS.VRPGSK......................VFACAGRSVTFAAAHRSR.ITANRPLRVVVTEACVDAVLARGAAE----VFDRGS..GVLPRALREIFYRL..
Q9Q924_RFVKA/1-215                 MPFRDLILFHLSKFLLTENEDSIKMFVSLCRGFDVNAEHLILTVLNKKYLKKLTKVI.RHEA.LLPEITVCFQDNIVYELIRLRLYKFSKQIKASYKLTESMKGIAYI.KDQKIYLSRVNDELLDFLLTEYTPHIYKYYP.GKPD.TIIGAK......................IILCGYNKITFFTYYTTH.VVTNQYINVIVTDKCIDSLLQPQHHSLLKKIFDGSS..DVINKVLKHIFYSV..
G2_VACCC/1-214                     MPFRDLILFNLSKFLLTEDEESLEIVSSLCRGFEISYDDLITYFPDRKYHKYISKVF.EHVD.LSEELSMEFHDTTLRDLVYLRLYKYSKCIRPCYKLGDNLKGIVVI.KDRNIYIREANDDLIEYLLKEYTPQIYTYSN.ERV-.PITGSK......................LILCGFSQVTFMAYTTSH.ITTNKKVDVLVSKKCIDELVDPINYQILQNLFDKGS..GTINKILRKIFYSV..
A0A097IVR3_9POXV/1-216             MPFIDLILFNISNFLLTENVDSIKNALSMCRCYGIDIEEFMVKYFNRRYANKIINILdNYTD.SLPFINISMPENALNELIRLRLINFSKHIKPSYKLTPTMNGMVII.KNNSVYIHSGNNELIEYILKEYSPNIYLYVF.SKPE.KINGSK......................IILCGYDMVTFFSYTVAN.IISNKKTDIIVTNNCIKNLSDPINISILINLFDNSN..NQINRILRKIFYSL..
A0A220T6C0_9POXV/1-215             MSFRDLILFNLIRFILLEDEDSMLLVSSLCRSFNIDVRELKNEIIDKRYFKYIDAIF.NCKK.LNTNILLNYPENIIYELVYLRLYKFSKFIKPSFKLSPTMKGTAII.KDNTISIRGLNEEFLNFLVKEYDPSIYIYTS.TLPK.SLYKSK......................IICCNYNKVTYYAYSIAH.IITNIKTDIIVTNKCINSLLLSDNEQILKSLFDKGE..GIINKILKKIFYSV..
Q77GD8_LSDVN/1-214                 MPFRDLILFHLSKFILTKNEESIKTTLSLCRGFDVDLEELMLSFLSKKYLKKLTN-I.EYNN.LLPELTISFPNDIVNELIKLRLYKFYKIIKPSLKLKNTMKGIVFI.KNRNVYILHTNDELIDFLFKEYDPYIYTYEI.DKPD.NLSGSK......................IILCGYDKVTFYTYLITK.IVTNQTVDIVVTDKCIELLLQPQNKQLLKDLFNNSN..DMINKILKKIFYSV..
A0A0G3G012_RACVI/1-214             MPFRDLILFNLSKFLLTEDTESLDRVSSLCRGFEISYDDLISYFPDRKYHRYISKVF.EHVN.LSDELSMEFHDATLYDLIYLRLYKYSKCIRPCYKLGDNLKGIVVI.KDTNIYIREANDDLIEYLLKEYTPQIYTYST.-KRV.PITGSK......................LILCGFSKVTFMAYTTSH.ITTNKKIDVLVTKKCINELTDPINYQILQNLFDKGS..GTINKILKKIFYSV..
Q9Q8P9_MYXVL/1-215                 MPFRDLILFHLSKFLLTENEDSIKMFVSLCRGFDINPEHLILSVLNKQYLKKLTKVI.RHEM.LLPDITVCFQDDIVNELLRLRLCKFSKQIKASYKLTASMKGIVYV.KDQKIYLSAVNDELLDFLLKEYTPHIYKYYP.GKPD.TIIGSK......................IILCGYDKITFFTYYTTH.VVTNQRVHVVVTDKCIDSLLQPQHHPLLKKIFDGSN..DVVNKVLKHIFYSV..
A9J1N0_VACCA/1-214                 MPFRDLILFNLSKFLLTEDEESLEIVSSLCRGFEISYDDLITYFPDRKYHKYIYKVF.EHVD.LSEELSMEFHDTTLRDLVYLRLYKYSKCIRPCYKLGDNLKGIVVI.KDRNIYIREANDDLIEYLLKEYTPQIYTYSN.ERV-.PIAGSK......................LILCGFSQVTFMAYTTSH.ITTNKKVDVLVSKKCIDELVDPINYQILQNLFDKGS..GTINKILRKIFYSV..
Q6TUW1_YMTV5/1-215                 MPFRDIILFYLSHFLLMDDEYSMKMAISLCRGFNIELSEIISEFKNKKFFNNIIKVF.ECKD.LMSEIIVCFPNNIIMTLIKLRLCKFSKTIKSSYKLNNTMNGIAII.KDRNIFVIKANDNFIDFLITKYNSQIYSYVK.EKPK.SLIGCK......................LIICGYSNVTFLAYTMAN.ITCNNNLKVVVTEKCIQELTKLQNIQLLKNLFDKGS..GTVNKVLRKVFYSV..
A0A0K1LD81_9POXV/1-214             MPFRDLILFNLSKFLLTEDEESLEIVSSLCRGFEISYDDLITYFPDRKYHKYIYKVF.EHVD.LSEELSMEFHDTTLRDLVYLRLYKYSKCIRPCYKLGDNLKGIVVI.KDRNIYIREANDDLIEYLLKEYTPQIYTYSN.EHV-.PIAGSK......................LILCGFSQVTFMAYTTSH.ITTNKKVDVLVSKKCIDELVDPINYQILQNLFDKGS..GTINKILRKIFYSV..
#=GC seq_cons                      MsFR-LILFpLuKFLLT-Dc-SlchssSLCRGFslshccLlspF.s++ah+hIs+lh.cpss.LhsElshpFP-ssl+-LlhLRLhKaoKsI+suYKLsssh+GIllI.cspslalpcAND-Ll-aLh+cYsPpIYpYsp.t+sp.slsGSK......................lIlCGaspVTFhAYpso+.IsoN+clcVlVT-cCIcpLlc..NhplLpslFD+Go..uslN+hL+cIFYSl..
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