GenomeNet

Database: Pfam
Entry: CoV_NSP2_N
LinkDB: CoV_NSP2_N
Original site: CoV_NSP2_N 
#=GF ID   CoV_NSP2_N
#=GF AC   PF19211.1
#=GF DE   Coronavirus replicase NSP2, N-terminal
#=GF PI   Corona_NS2_N;
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   Bateman A
#=GF GA   28.00 28.00;
#=GF TC   87.00 85.30;
#=GF NC   27.90 27.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16227261
#=GF RT   The nsp2 replicase proteins of murine hepatitis virus and severe
#=GF RT   acute respiratory syndrome coronavirus are dispensable for viral
#=GF RT   replication.
#=GF RA   Graham RL, Sims AC, Brockway SM, Baric RS, Denison MR;
#=GF RL   J Virol. 2005;79:13399-13411.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry corresponds to the N-terminal region of coronavirus
#=GF CC   non-structural protein 2. NSP2 is encoded by ORF1a/1ab and
#=GF CC   proteolytically released from the pp1a/1ab polyprotein. The
#=GF CC   function of this protein is uncertain. This region contains
#=GF CC   numerous conserved and semi-conserved cysteine residues.
#=GF SQ   84
#=GS B1PHI7_9ALPC/111-318      AC B1PHI7.1
#=GS R1A_CVPPU/110-310         AC P0C6V2.1
#=GS H9TEW9_9ALPC/110-310      AC H9TEW9.1
#=GS Q6UZF5_CVHSA/182-423      AC Q6UZF5.1
#=GS R1A_CVEMC/194-443         AC K9N638.1
#=GS R1A_BCHK5/196-441         AC P0C6T5.1
#=GS A0A125R5A3_9ALPC/110-310  AC A0A125R5A3.1
#=GS A0A0U1WHF6_9ALPC/111-315  AC A0A0U1WHF6.1
#=GS A0A0U1WHL2_BCHK5/196-441  AC A0A0U1WHL2.1
#=GS R1A_PEDV7/111-316         AC P0C6V6.1
#=GS B1PHJ4_9ALPC/111-318      AC B1PHJ4.1
#=GS I1VWF3_CVH22/112-316      AC I1VWF3.1
#=GS R1AB_FIPV/110-310         AC Q98VG9.2
#=GS R1AB_PEDV7/111-316        AC P0C6Y4.1
#=GS A0A1X9JQL5_9ALPC/114-287  AC A0A1X9JQL5.1
#=GS E0ZN35_BCHK9/191-395      AC E0ZN35.1
#=GS A3EXI1_BCHK9/191-395      AC A3EXI1.1
#=GS A0A0U2GN93_CVH22/112-316  AC A0A0U2GN93.1
#=GS S5Z1D1_9ALPC/111-314      AC S5Z1D1.1
#=GS A3EXE7_BCHK5/196-441      AC A3EXE7.1
#=GS K4JZT2_9ALPC/111-315      AC K4JZT2.1
#=GS Q6RD33_CVHSA/182-423      AC Q6RD33.1
#=GS R1AB_BC512/111-320        AC P0C6W0.1
#=GS I1VWF4_CVH22/112-316      AC I1VWF4.1
#=GS A3EXI9_BCHK9/191-395      AC A3EXI9.1
#=GS R1AB_CVEMC/194-443        AC K9N7C7.1
#=GS R1A_BC512/111-320         AC P0C6F6.1
#=GS B1PHI6_9ALPC/111-318      AC B1PHI6.1
#=GS A3EXA2_BCHK4/196-440      AC A3EXA2.1
#=GS V9PIT1_9ALPC/110-310      AC V9PIT1.1
#=GS A0A0K1Z0N1_CVHSA/182-423  AC A0A0K1Z0N1.1
#=GS B1PHK0_9ALPC/113-316      AC B1PHK0.1
#=GS B1PHJ3_9ALPC/111-318      AC B1PHJ3.1
#=GS H9TEX0_9ALPC/110-310      AC H9TEX0.1
#=GS A0A0K1YZY7_CVHSA/182-423  AC A0A0K1YZY7.1
#=GS D9J203_9ALPC/111-312      AC D9J203.1
#=GS D9J202_9ALPC/111-312      AC D9J202.1
#=GS R1AB_BCHK5/196-441        AC P0C6W4.1
#=GS A0A096XNJ3_9ALPC/114-290  AC A0A096XNJ3.2
#=GS A0A023YA54_9BETC/196-445  AC A0A023YA54.1
#=GS A0A125R5A4_9ALPC/110-310  AC A0A125R5A4.1
#=GS R1A_CVHNL/111-315         AC P0C6U6.1
#=GS R1AB_BCHK9/191-395        AC P0C6W5.1
#=GS R1AB_CVH22/112-316        AC P0C6X1.1
#=GS A0A0U1UZC3_9ALPC/112-317  AC A0A0U1UZC3.1
#=GS B1PHK1_9ALPC/113-316      AC B1PHK1.1
#=GS R1A_CVHSA/182-423         AC P0C6U8.1
#=GS B8Q8Q2_CVHSA/182-423      AC B8Q8Q2.1
#=GS R1AB_BCHK4/196-440        AC P0C6W3.1
#=GS B8Q8Q1_CVHSA/182-423      AC B8Q8Q1.1
#=GS Q6RD32_CVHSA/182-423      AC Q6RD32.1
#=GS A0A1B3Q5W8_9BETC/191-395  AC A0A1B3Q5W8.1
#=GS A0A0U1UZ65_BCHK4/196-440  AC A0A0U1UZ65.1
#=GS R1A_CVH22/112-316         AC P0C6U2.1
#=GS A0A0U1WHG0_CVHSA/182-423  AC A0A0U1WHG0.1
#=GS A0A172B201_9ALPC/111-312  AC A0A172B201.1
#=GS T2B9U0_9BETC/194-443      AC T2B9U0.1
#=GS A0A096XNP3_CVHSA/182-423  AC A0A096XNP3.1
#=GS A0A0U2GMU3_CVH22/112-316  AC A0A0U2GMU3.1
#=GS A0A0U1WHG4_9ALPC/111-315  AC A0A0U1WHG4.1
#=GS R1AB_CVHSA/182-423        AC P0C6X7.1
#=GS R1AB_CVHNL/111-315        AC P0C6X5.1
#=GS T2B9I2_9BETC/194-443      AC T2B9I2.1
#=GS A0A1L2KGB4_9ALPC/111-315  AC A0A1L2KGB4.1
#=GS A0A088DIE1_9BETC/177-416  AC A0A088DIE1.1
#=GS U5LR11_9BETC/201-450      AC U5LR11.1
#=GS S5YAF0_9ALPC/111-314      AC S5YAF0.1
#=GS A0A0U1WHD1_9ALPC/113-316  AC A0A0U1WHD1.1
#=GS Q0PL14_9ALPC/110-310      AC Q0PL14.1
#=GS R9QTH2_CVHSA/182-423      AC R9QTH2.1
#=GS A0A1L2KGB5_9ALPC/111-315  AC A0A1L2KGB5.1
#=GS U5KNA9_9BETC/201-450      AC U5KNA9.1
#=GS K4K1U5_9ALPC/111-315      AC K4K1U5.1
#=GS E0ZN43_BCHK9/191-395      AC E0ZN43.1
#=GS A0A059VJE6_9ALPC/111-316  AC A0A059VJE6.1
#=GS R9QTB2_CVHSA/182-423      AC R9QTB2.1
#=GS A0A166ZL34_9NIDO/182-423  AC A0A166ZL34.1
#=GS D5HJV7_BCHK3/182-423      AC D5HJV7.1
#=GS R1A_BCHK4/196-440         AC P0C6T4.1
#=GS R1AB_CVPPU/110-310        AC P0C6Y5.1
#=GS A0A240FW17_9ALPC/111-292  AC A0A240FW17.1
#=GS R1A_BCHK9/191-395         AC P0C6T6.1
#=GS A0A0U1WHG1_9ALPC/109-313  AC A0A0U1WHG1.1
#=GS A0A172B3C8_9ALPC/111-312  AC A0A172B3C8.1
B1PHI7_9ALPC/111-318                 .t-SIPVDNYMCGANGKPVITEDMWYFCD...YFGDDGDK...........ITINGQEYHKA.......WNVTRS.DVPYQFQNAGTILSIEYV....STEAHVL..PDGAIAKTAKPPKFSKNVVLSEKCKALYDACGSPFVTNgtnvlevvTNPIFAHGFVQCK-CGSKHWTTGDWS.GFKSVCCGTPG.RVLCT..-VFGGVTPGSI-..........................LLTSTRVDAtpgATRY...YHGLTLKHI......CNVDDVACW........
R1A_CVPPU/110-310                    ga--IYVDQYMCGADGKPVIEG---DFKD...YFGDEDI-...........IEFEGEEYHCA.......WTTVRD.EKPLNQQTLFTIQEIQYN....LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDIKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQYA......GDVEGVSIW........
H9TEW9_9ALPC/110-310                 ga--IYVDQYMCGADGKPVIEG---DFKD...YFGDEDV-...........IEFEGEDYHCA.......WTVVRD.EKPLNQQTLFTIQEIQYN....LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYRKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDVKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQHA......GDVENVSIW........
Q6UZF5_CVHSA/182-423                 .v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW........
R1A_CVEMC/194-443                    ..DVTPVDQYMCGVDGKPISAYAFLMAKDgitKLADVEADvaara.ddegfITLKNNLYRLV.......WHVERK.DVPYPKQSIFTINSVVQKdgveNTPPHYF.tLGCKILTLTPRNKWSGVSDLSLKQKLLYTFYGKESLEN........PTYIYHSAFIECGSCGNDSWLTGNAIqGFACGCGASYTaNDVEV..QSSGMIKPNALLcatcpfakgdscssnckhsvaqlvsyLSERCNVIA..dSKSFtliFGGVAYAYF......GCEEGTMYF........
R1A_BCHK5/196-441                    .d-FTPIDQYMCGKNGKPIAEFAALMASEgitKLADVEAEvksrt.dsdryIVFKNKLYRIV.......WNVQRK.DVAYSKQSAFTMNSIVQLd.tmEDVPRHSftIGSEIQVIAPSTAVQANGHLNLKQRLLYAFYGKQAVSE........PNYIYHSAYVDCTSCGKGSWLTGNAVqGFACDCGAHYCaNDVDL..QSSGLVRKNAVLlttcpcnkdge....ckhtlpqlvsmMTDKCDVEV..vGKTFiltYGGVIYAYM......GCSGGTMHF........
A0A125R5A3_9ALPC/110-310             ga--IYVDQYMCGADGKPVIEG---EFKD...YFGDEDV-...........IIYEGEEYHCA.......WLTVRD.EKPLCQQNLLTIKEIQYN....LDIPHKL..PNCAIREVAPPVKKNSKVVLSEDYRKLYDIFGSPFMGNgdslnkcfANLHFIAATLKCP-CGAESSGVGDWT.GFKTACCGLHG.KVKGV..-TLGAVKPGDA-..........................VITSMSAGK...GVKF...FANSVLQYA......GDVENVSVW........
A0A0U1WHF6_9ALPC/111-315             ..NVVFVDNYMCGADGKPAVPREQWSFEE...HFDDDTED...........IIINGVTYRHA.......WNTIRA.DDPYEKQGLLSIKSIEYV....STIPHKL..PNGSVLSVAGPPKKRKAVVLDEKYNKIYNACGVPFVTNgksisevvTKPLFLHALVKCK-CGNESWTVGDWT.GFKTTCCGATG.KVTTF..-AVGDVTPGDI-..........................VFTTTGAGT...GTKF...FCGLVLTHV......DTLEGVSAW........
A0A0U1WHL2_BCHK5/196-441             .d-FTPIDQYMCGKNGKPIAEFAALMASEgitKLADVEAEvksrt.dldryTVFKNKLYRIV.......WNVQRK.DVAYSKQSAFTMNSIVQLd.tmEDVPRHSftIGSEIQVIAPSTAVQANGHLNLKQRLLYAFYGKQAVSE........PNYIYHTAYVDCTSCGKGSWLTGNAVqGFACDCGAHYCaNDVDL..QSSGLVRKNAVLlttcpcnkdge....ckhtlpqlvsmMTDKCDVEV..vGKTFiltYGGVIYAYM......GCSGGTMHF........
R1A_PEDV7/111-316                    .n-IVPVDQYMCGADGKPVLQESEWEYTD...FFADSEDG..........qLNIAGITYVKA.......WIVERS.DVSYASQNLTSIKSITYC....STYEHTF..LDGTAMKVARTPKIKKNVVLSEPLATIYREIGSPFVDNgsdarsiiRRPVFLHAFVKCK-CGSYHWTVGDWT.SYVSTCCGFKC.KPVLV..-ASCSAMPGSV-..........................VVTRAGAGT...GVKY...YNNMFLRHV......ADIDGLAFW........
B1PHJ4_9ALPC/111-318                 .t-SIPVDNYMCGANGKPVLPEDMWCFCD...YFGDDGDN...........ITVNGQAYHKA.......WNVTRG.DVPYQFQNASTILSIEYL....ADEKHVL..PDGAVAKSAKPPKFSKNIVLSEKYKALYDACGNPFVTNgtnvlevvTNPIFAHGFVQCK-CGSKHWTTGDWA.GFKSVCCGIPG.RVLCT..-VFGGVAPGSV-..........................LLTSTRVDAspgATRY...YHGLTLKHI......CNVDGVACW........
I1VWF3_CVH22/112-316                 ..NVTYTDQYLCGADGKPVISDDLWQFVD...HFGENEE-...........IIINGHTYVCA.......WLTKRK.PLDYKRQNNLAIEEIEYV...rGDALHTL..RNGSVLEMAKEVKTSSKVVLSDALDKLYKVFGSPVMTNgsnileafIKPVFISAFVQCT-CGNKSWSVGDWT.GFKSTCCNVLS.KKLCV..-VPGNVKPGDA-..........................VVTTQQAGV...GVKY...FCGMTLKFV......ANIEGVSVW........
R1AB_FIPV/110-310                    ga--IYVDQYMCGADGKPVIEG---EFKD...YFGDEDV-...........IIYEGEEYHCA.......WLTVRD.EKPLWQQTLLTIREIQYN....LDIPHKL..PNCAIREVAPPVKKNSKVVLSEEYRKLYDIFGSPFMGNgdslntcfDSLHFIAATLKCP-CGAESSGVGDWT.GFKTACCGLHG.KVKGV..-TLGAVKPGDA-..........................IVTSMSAGK...GVKF...FANSVLQYA......GDVENVSVW........
R1AB_PEDV7/111-316                   .n-IVPVDQYMCGADGKPVLQESEWEYTD...FFADSEDG..........qLNIAGITYVKA.......WIVERS.DVSYASQNLTSIKSITYC....STYEHTF..LDGTAMKVARTPKIKKNVVLSEPLATIYREIGSPFVDNgsdarsiiRRPVFLHAFVKCK-CGSYHWTVGDWT.SYVSTCCGFKC.KPVLV..-ASCSAMPGSV-..........................VVTRAGAGT...GVKY...YNNMFLRHV......ADIDGLAFW........
A0A1X9JQL5_9ALPC/114-287             np--IFVDQYLCGADGTPVK--RDVEFKN...YFTDGDT-...........YVEPGKTYKLV.......WNVERK.PGDL---TLSGILSIKYL....SDKPHKL..RDGVVQEVADAVS-----ELNDT---------KQLV--........---RFIHGFVSCP-CGKSAFTVGGWN.GFATVCCGVTVkSPICV..KFSGKA--GSIF.........................aLPLGSRVFG...TKRI...YAGAEFQYC......CDLSGVEIW........
E0ZN35_BCHK9/191-395                 .l-VKPVLELLGGIKPDLTLEKLTLALSE...YRNSDG--...........YDLPGGFVRVA.......VSVIRK.PVPVVKQTIFTVQGVVEQhvegFYYPYS-..TMSVVKHTKPRSDKPLGKTVESIMLSLYGTSG------........YSPATPVVRLRCSYCDFYGWVPPRDMgTVVCSCGAEFQlTSACVdaESAGAIKPGCVM..........................LLDRSPGMRlipGNRIyvaFGGAIWSPI......GTVNGVSVW........
A3EXI1_BCHK9/191-395                 .l-VKPVLELLGGIKPDLTLEKLTLALSE...YRNSDG--...........YDLPGGFVRVA.......VSVIRK.PVPVVKQTIFTVQGVVEQhvegFYYPYS-..TMSVVKHTKPRSDKPLGKTVESIMLSLYGTSG------........YSPATPVVRLRCSYCDFYGWVPPRDMgTVVCSCGAEFQlTSACVdaESAGAIKPGCVM..........................LLDRSPGMRlipGNRIyvaFGGAIWSPI......GTVNGVSVW........
A0A0U2GN93_CVH22/112-316             ..NVTYTDQYLCGADGKPVISDDLWQFVD...HFGENEE-...........IIINGHTYVCA.......WLTKRK.PLDYKRQNNLAIEEIEYV...rGDALHTL..RNGSVLEMAKEVKTSSKVVLSDALDKLYKVFGSPVMTNgsnildafIKPVFISAFVQCT-CGNKSWSVGDWT.GFKSTCCNVLS.NKLCV..-VPGNVKPGDA-..........................VVTTQQAGV...GVKY...FCGMTLKFV......ANIEGVSVW........
S5Z1D1_9ALPC/111-314                 ..NTIYVDQYLCGADGKPVVPEEFWDFKD...YFVDDDQ-...........VVVNGTTYIKA.......WVVERA.NVAYEAQNVTAINGITYC....AKIPHTL..PDGSVVRVARKPKIKKSIVLSDVYKPLLEGLGAPFVKNgdtlasilTEPVFLHALVKCT-CGKTMWTVGDWS.CYKSLCCGVVC.KPLCN..-VAGIVNPGSA-..........................VVTRTGLGS...GIKY...YCGMFLRHI......LDVDGVSVW........
A3EXE7_BCHK5/196-441                 .d-FTPIDQYMCGKNGKPIAEFAALMASEgitKLADVEAEvksrt.dsdryIVLKNKLYRIV.......WNVQRK.DVAYSKQSAFTMNSIVQLd.tmEDVPRHSftIGSEIQVIAPSTAVQANGHLNLKQRLLYAFYGKQAVSE........PNYIYHSAYVDCTSCGKGSWLTGNAVqGFACDCGAHYCaNDVDL..QSSGLVRKNAVLlttcpcnkdge....ckhtlpqlvsmMTDKCDVEV..vGKTFiltYGGVIYAYM......GCSGGTMHF........
K4JZT2_9ALPC/111-315                 .t-TVFVDNFLCGANGLPACSEQEWEFKD...YFGELDE-...........VIINGTTFVKA.......WNVDRT.PGPYSTQNLLSINSISWC....GEIPHSL..ADGSIRRVAKVVKKSKSVLLGKQFQQLYDSVGSPFVTNgknltdvlVKPIYCHALVKCQ-CGKTSWTVGDWS.CYKSMCCGFNC.KPLAI..-VNGEVVPGDV-..........................LVTSDKVSA..sGTKY...YNGMVLKFV......DKIDNACLW........
Q6RD33_CVHSA/182-423                 .v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKXYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW........
R1AB_BC512/111-320                   .t-TIPVDQFMCGADGAPVIQEGDWTFMD...YFQDSNQ-...........FTLNGITYVKA.......WDVDRK.PNDYAKQNVTCIRRITYI....TDHRHVL..ADGTTMKTARHPKVNKSVVLDSPFDQIYKEVGSPFMGNgstfvemlKDPAFFHALITCE-CGRSEWTVGDWK.GYNSLCCNIKC.KPITI..-VTPKAVPGAV-..........................VITKAGIGA...GLKC...YNNVFLKHIidlvvpG--------tnlgwgvw
I1VWF4_CVH22/112-316                 ..NVTYTDQYLCGADGKPVISDDLWQFVD...HFGENEE-...........IIINGHTYVCA.......WLTKRK.PLDYKRQNNLAIEEIEYV...rGDALHTL..RNGSVLEMAKEVKTSSKVVLSDALDKLYKVFGSPVMTNgsnileafIKPVFISAFVQCT-CGNKSWSVGDWT.GFKSTCCNVLS.KKLCV..-VPGNVKPGDA-..........................VVTTQQAGV...GVKY...FCGMTLKFV......ANIEGVSVW........
A3EXI9_BCHK9/191-395                 .l-VKPVQDLLGDIRPDFTLEELTLCLSD...YRTDDG--...........YDLLGGYVKVA.......VKVVRK.PVPVVKQTIFTVQGVIEQc.veGYYYPFP..PMSAVKHTKPRSDKPLGKTVDSIMLSLYGTSG------........YNPATPVVRLRCSHCDFYGWVPLKDMgTVSCSCSAVHQlTSSCIdaESAGAIKPGCVM..........................LLDKSPGMRvipGNRTyvaFGGAIWSPI......GKVGDVTVW........
R1AB_CVEMC/194-443                   ..DVTPVDQYMCGVDGKPISAYAFLMAKDgitKLADVEADvaara.ddegfITLKNNLYRLV.......WHVERK.DVPYPKQSIFTINSVVQKdgveNTPPHYF.tLGCKILTLTPRNKWSGVSDLSLKQKLLYTFYGKESLEN........PTYIYHSAFIECGSCGNDSWLTGNAIqGFACGCGASYTaNDVEV..QSSGMIKPNALLcatcpfakgdscssnckhsvaqlvsyLSERCNVIA..dSKSFtliFGGVAYAYF......GCEEGTMYF........
R1A_BC512/111-320                    .t-TIPVDQFMCGADGAPVIQEGDWTFMD...YFQDSNQ-...........FTLNGITYVKA.......WDVDRK.PNDYAKQNVTCIRRITYI....TDHRHVL..ADGTTMKTARHPKVNKSVVLDSPFDQIYKEVGSPFMGNgstfvemlKDPAFFHALITCE-CGRSEWTVGDWK.GYNSLCCNIKC.KPITI..-VTPKAVPGAV-..........................VITKAGIGA...GLKC...YNNVFLKHIidlvvpG--------tnlgwgvw
B1PHI6_9ALPC/111-318                 .t-SIPVDNYMCGANGKPVITEDMWYFCD...YFGDDGDK...........ITINGQEYHKA.......WNVTRS.DVPYQFQNAGTILSIEYV....STEAHVL..PDGAIAKTAKPPKFSKNVVLSEKCKALYDACGSPFVTNgtnvlevvTNPIFAHGFVQCK-CGSKHWTTGDWS.GFKSVCCGTPG.RVLCT..-VFGGVTPGSI-..........................LLTSTRVDAtpgATRY...YHGLTLKHI......CNVDDVACW........
A3EXA2_BCHK4/196-440                 .d-CIPIDQYMCGKNGKPIADYAKIVAKEgltTLADIEVDvksrm.dsdrfIVLNKKLYRVV.......WNVTRR.NVPYPKQTAFTIVSVVQCd.dkDSVPEHTftIGSQILMVSP-LKATNNKNFNLKQRLLYTFYGKDAVQQ........PGYIYHSAYVDCNACGRGTWCTGNAIqGFACDCGANYSaNDVDL..QSSGLVPRNALFlancpcannga....cshsaaqvyniLDGKACVEV..gGKSFtltFGGVVYAYM......GCCDGTMYF........
V9PIT1_9ALPC/110-310                 ga--IYVDQYMCGADGKPVIEG---EFKD...YFGDEDV-...........IIYEGEEYHCA.......WLTVRD.EKPLCQQTLLTIREIQYN....LDIPHKL..PNCAIREVAPPVKKNSKVVLSEEYRKLYDIFGSPFMGNgdslntcfDSLHFIAATLKCP-CGAESSGVGDWT.GFKTACCGLHG.KVKGV..-TLGAVKPGDA-..........................IVTSMSAGK...GVKF...FANSVLQYA......GDVENVSVW........
A0A0K1Z0N1_CVHSA/182-423             .v-TRYVDNNFCGPDGYPLE-----CIKG...LLARAGKSmctls.eqldfIESKRGVYCCReheheiaWYTERS.DKSYEHQTPFDIKSAKKFdtfkEECPKFVfpLNSTVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCSHCDEVSWQTCDFL.KATCEHCGTEN.LVVEG.pTTCGYLPINAVVkmpcpacqnkevgpehsvadyhnysnIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW........
B1PHK0_9ALPC/113-316                 sp--VYVDNYMCGANGKPVLPADVWVYQD...YFGEETE-...........LIVNGVKHVKV.......WHVTRT.DIPYQFQSLGAIESIEWL....TDIPHTL..RNGSRLSAARAVKHSKNVVLSEPLKTLYQACGSPFVTNgstlreavPKPVFAHAYVACK-CGRKAWSVGDWS.GYKSTCCGVFG.KPQCV..-VFGEVVPGDV-..........................FITTSSVGS...GTRY...YNGLTVKHV......VTVDGLACW........
B1PHJ3_9ALPC/111-318                 .t-SIPVDNYMCGANGKPVLPEDMWCFCD...YFGDDGDN...........ITVNGQAYHKA.......WNVTRG.DVPYQFQNASTILSIEYL....ADEKHVL..PDGAVAKSAKPPKFSKNIVLSEKYKALYDACGNPFVTNgtnvlevvTNPIFAHGFVQCK-CGSKHWTTGDWA.GFKSVCCGIPG.RVLCT..-VFGGVAPGSV-..........................LLTSTRVDAspgATRY...YHGLTLKHI......CNVDGVACW........
H9TEX0_9ALPC/110-310                 ga--IYVDQYMCGADGKPVIEG---DFKD...YFGDEDV-...........IEFEGEDYHCA.......WTVVRD.EKPLNQQTLFTIQEIQYN....LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYRKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDVKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQHA......GDVENVSIW........
A0A0K1YZY7_CVHSA/182-423             .v-TRYVDNNFCGPDGYPLE-----CIKG...LLARAGKSmctls.eqldfIESKRGVYCCReheheiaWYTERS.DKSYEHQTPFDIKSAKKFdtfkEECPKFVfpLNSTVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCSHCDEVSWQTCDFL.KATCEHCGTEN.LVVEG.pTTCGYLPINAVVkmpcpacqnkevgpehsvadyhnysnIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW........
D9J203_9ALPC/111-312                 .t-VVHVDQFLCGADGKPVRQG---DMKD...YFGDLEE-...........IVIDGITYQHA.......WDVVRDvEVPHAKQTALNVQSIMYL....MDVDHKL..VNGATRQRAAPVKISSKVCLTEPYNSLYKHFGSPYMQNggnlnecfAKLNFIVANVKCK-CGGESSGVGDWT.GFKSACCGTPG.KVIGV..-SIGDASVGEA-..........................VITSKGCGT...GTKF...YAGAVLKYV......GDAEGVSVW........
D9J202_9ALPC/111-312                 .t-VVHVDQFLCGADGKPVRQG---DMKD...YFGDLEE-...........IVIDGITYQHA.......WDVVRDvEVPHAKQTALNVQSIMYL....MDVDHKL..VNGATRQRAAPVKISSKVCLTEPYNSLYKHFGSPYMQNggnlnecfAKLNFIVANVKCK-CGGESSGVGDWT.GFKSACCGTPG.KVIGV..-SIGDASVGEA-..........................VITSKGCGT...GTKF...YAGAVLKYV......GDAEGVSVW........
R1AB_BCHK5/196-441                   .d-FTPIDQYMCGKNGKPIAEFAALMASEgitKLADVEAEvksrt.dsdryIVFKNKLYRIV.......WNVQRK.DVAYSKQSAFTMNSIVQLd.tmEDVPRHSftIGSEIQVIAPSTAVQANGHLNLKQRLLYAFYGKQAVSE........PNYIYHSAYVDCTSCGKGSWLTGNAVqGFACDCGAHYCaNDVDL..QSSGLVRKNAVLlttcpcnkdge....ckhtlpqlvsmMTDKCDVEV..vGKTFiltYGGVIYAYM......GCSGGTMHF........
A0A096XNJ3_9ALPC/114-290             np--IYVDQYLCGPDGTPVK--KGLEFKD...YFMNGGDI...........YVEPGKTYVRV.......WDVERK.QDDL---TLDGILSIKYL....SDKPHKL..RDGAIQGVADAVSE-----LND-------T-------N........QMVRFIHAFVSCP-CGKSAFTVGSWM.GFATVCCGKIVkTPMCV..KFSGEAGSIFAL..........................PVGSRGFSA..nGKRS...YAGAEFQFC......CELSGVEIW........
A0A023YA54_9BETC/196-445             .d-FIPIDQFMCGKDGAPVPDYATLAASEnliSLADVATDvsara.dsdgyIDFKSKLYRIV.......WHVERK.NVPYAKQTIFTINSVVQCdgiqDVPPHTF.tLGGKVDLIVPRNKWTGKTALNLKQKILYTFYGKDALDN........HSYIYHSAYADCTSCGKGSWLTGNAVqGFACDCGAQYSaNDVEL..QSSGVVNPNAIFcatcpfakgdscsssckhtlaqmvsqLSEKCDVAP..dGKSFtlaFGGVVYAYL......GCLEGTMYF........
A0A125R5A4_9ALPC/110-310             ga--IYVDQYMCGADGKPVIEG---EFKD...YFGDEDV-...........IIYEGEEYHCA.......WLTVRD.EKPLCQQNLLTIKEIQYN....LDIPHKL..PNCAIREVAPPVKKNSKVVLSEDYRKLYDIFGSPFMGNgdslnkcfANLHFIAATLKCP-CGAESSGVGDWT.GFKTACCGLHG.KVKGV..-TLGAVKPGDA-..........................VITSMSAGK...GVKF...FANSVLQYA......GDVENVSVW........
R1A_CVHNL/111-315                    .s-VVFVDKYMCGFDGKPVLPKNMWEFRD...YFNNNTDS...........IVIGGVTYQLA.......WDVIRK.DLSYEQQNVLAIESIHYL....GTTGHTL..KSGCKLTNAKPPKYSSKVVLSGEWNAVYRAFGSPFITNgmslldiiVKPVFFNAFVKCN-CGSESWSVGAWD.GYLSSCCGTPA.KKLCV..-VPGNVVPGDV-..........................IITSTSAGC...GVKY...YAGLVVKHI......TNITGVSLW........
R1AB_BCHK9/191-395                   .l-VEPVMKLLGVIKSDFTLEQLLAALGK...YRTEDG--...........YDLPDGYVKVA.......IKVGRK.AVPVLKQSIFTVVGVTEQlvpgYYYPFS-..TSSVVEHTKPTRGGPVGKTVEAVMLSLYGTNN------........YNPATPVARLKCSYCDYYGWTPLKDIgTVNCLCGAEFQlTSSCVdaESAGVIKPGCVM..........................LLDKSPGMRlipGNRTyvsFGGAIWSPI......GKVNGVTVW........
R1AB_CVH22/112-316                   ..NVTYTDQYLCGADGKPVMSEDLWQFVD...HFGENEE-...........IIINGHTYVCA.......WLTKRK.PLDYKRQNNLAIEEIEYV...hGDALHTL..RNGSVLEMAKEVKTSSKVVLSDALDKLYKVFGSPVMTNgsnileafTKPVFISALVQCT-CGTKSWSVGDWT.GFKSSCCNVIS.NKLCV..-VPGNVKPGDA-..........................VITTQQAGA...GIKY...FCGMTLKFV......ANIEGVSVW........
A0A0U1UZC3_9ALPC/112-317             pp--IYVDNYLCGADGTPVVQESMWSYTD...HFGEDCDE...........ITLCGITYVHA.......WNVQRA.DVPYEQQNVTSIFSIEYL....LDVDHAL..QNGAVLNVASGVKYKKSVVLSEGFKKLYDACGVPAVQNgntlvdilTKPAFFHAIVSCS-CGLSSYTVGDWKiGFRSLCCGKRL.EPITV..-VVGDVKPGDI-..........................VVTSANAGD...GVRY...FNGLTLQYV......GDWEGVSCW........
B1PHK1_9ALPC/113-316                 sp--VYVDNYMCGANGKPVLPADVWVYQD...YFGEETE-...........LIVNGVKHVKV.......WHVTRT.DIPYQFQSLGAIESIEWL....TDIPHTL..RNGSRLSAARAVKHSKNVVLSEPLKTLYQACGSPFVTNgstlreavPKPVFAHAYVACK-CGRKAWSVGDWS.GYKSTCCGVFG.KPQCV..-VFGEVVPGDV-..........................FITTSSVGS...GTRY...YNGLTVKHV......VTVDGLACW........
R1A_CVHSA/182-423                    .v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW........
B8Q8Q2_CVHSA/182-423                 .v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW........
R1AB_BCHK4/196-440                   .d-CIPIDQYMCGKNGKPIADYAKIVAKEgltTLADIEVDvksrm.dsdrfIVLNKKLYRVV.......WNVTRR.NVPYPKQTAFTIVSVVQCd.dkDSVPEHTftIGSQILMVSP-LKATNNKNFNLKQRLLYTFYGKDAVQQ........PGYIYHSAYVDCNACGRGTWCTGNAIqGFACDCGANYSaNDVDL..QSSGLVPRNALFlancpcannga....cshsaaqvyniLDGKACVEV..gGKSFtltFGGVVYAYM......GCCDGTMYF........
B8Q8Q1_CVHSA/182-423                 .v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW........
Q6RD32_CVHSA/182-423                 .v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKXYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW........
A0A1B3Q5W8_9BETC/191-395             la--APIKEVLGGKGAGMSLVELTKFLGK...YRTADG--...........YELPSGIVKVA.......VKVVRK.NLPVSKQSIFTVLGVTERvvdgFYYPYS-..TNSVVSYTKPRAGATVGNTVQSVMLSMYGTEA------........YNPVTPVVRLRCSSCDFYGWVPVKDLgCVTCSCAAVHQiTSSCIdaESAGLIKQGAVM..........................LVDRSPSMRvvpGNRLyvaFGGAIWSPI......GKVNGVQVW........
A0A0U1UZ65_BCHK4/196-440             .d-CIPVDQYMCGKNGKPIADYAKIVAKEgltTLADIEVDvksrm.dldrfIVLNKKLYRVV.......WNVTRR.NVPYSKQTAFTVVSVVQCd.dkESVPEHTftIGSQILMVSP-LKATNNKNFNLKQRLLHTFYGKEAVQQ........PGYIYHSAYVDCNACGRGTWCTGNAIqGFACDCGANYSaNDVDL..QSSGLVPKNALFlancpcanngs....cshsaaqvysiLDGKACVEF..gGKSFtltFGGVVYAYM......GCCDGTMYF........
R1A_CVH22/112-316                    ..NVTYTDQYLCGADGKPVMSEDLWQFVD...HFGENEE-...........IIINGHTYVCA.......WLTKRK.PLDYKRQNNLAIEEIEYV...hGDALHTL..RNGSVLEMAKEVKTSSKVVLSDALDKLYKVFGSPVMTNgsnileafTKPVFISALVQCT-CGTKSWSVGDWT.GFKSSCCNVIS.NKLCV..-VPGNVKPGDA-..........................VITTQQAGA...GIKY...FCGMTLKFV......ANIEGVSVW........
A0A0U1WHG0_CVHSA/182-423             .v-TRYVDNNFCGPDGYPLD-----CIKD...LLARAGKSmctlp.eqldfIESKRGVYCCReheheiaWYTERS.DKSYEHQTPFEVKIAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKNTEGFMGRIRSVYQVATPNECND........---MHLSVFMKCNHCDEASWQTCDFL.KATCEYCGTE-.NPVSEgpTTCGYLPTNAVVkmpcpacqnkevgpehsvadyhnhssIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW........
A0A172B201_9ALPC/111-312             .m-TVYVDQYMCGADGRPVISG---EMRD...YFGDLDD-...........IVIDGIIYSHA.......WDVERDlDVTHDKQTFLNIKSIMYL....QDKDHKL..PNGAIRVRAAPVKLSSKVVLSQPFADMYKHFGSPYMQNgdnlhgcfTKLNFIVANVKCK-CGGESSGVGDWT.GFKSACCGLPG.KVIGV..-SLGNAAVGEA-..........................VVTSKGCGN...GTKF...YANAVLKHV......GDADDVSIW........
T2B9U0_9BETC/194-443                 ..DVTPVDQYMCGVDGKPISAYAFLMAKDgitKLADVEADvaara.ddegfITLKNNLYRLV.......WHVERK.DVPYPKQSIFTINSVVQKdgveNTPPHYF.tLGCKILTLTPRNKWSGVSDLSLKQKLLYTFYGKESLEN........PTYIYHSAFIECGSCGNDSWLTGNAIqGFACGCGASYTaNDVEV..QSSGMIKPNALLcatcpfakgdscssnckhsvaqlvsyLSERCNVIA..dSKSFtliFGGVAYAYF......GCEEGTMYF........
A0A096XNP3_CVHSA/182-423             .v-TRYVDNNFCGPDGYPLE-----CIKD...LLARAGKSlctls.eqldyIESKRGVYCCReheheivWFTERS.EKSYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVATPQECND........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEQCGTE-.NLVCEgpTTCGYLPTNAVVkmpcpacqdpevgpehsvadyhnhsnIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW........
A0A0U2GMU3_CVH22/112-316             ..NVTYTDQYLCGADGKPVISDDLWQFVD...HFGENEE-...........IIINGHTYVCA.......WLTKRK.PLDYKRQNNLAIEEIEYV...rGDALHTL..RNGSVLEMAKEVKTSSKVVLSDALDKLYKVFGSPVMTNgsnildafIKPVFISAFVQCT-CGNKSWSVGDWT.GFKSTCCNVLS.NKLCV..-VPGNVKPGDA-..........................VVTTQQAGV...GVKY...FCGMTLKFV......ANIEGVSVW........
A0A0U1WHG4_9ALPC/111-315             ..NTVYVDNYMCGSNGVPVLPEDQWEFVD...YFGELTE-...........VSIGDTTYIKA.......WNVDRV.EGPYKSQTLLSINAISYC....GEVIHAL..ADGSTMSYATAVKKNSKTVVNKTYQKLYDNIGVPFVTNgkvlteiiPKPVFNHGLVKCH-CGKVSWTVGDWS.CYKSTCCGTVC.KPIAI..-VNGDVNPGDV-..........................VITSKQVAT..nGVKY...YNGMVLKYV......DTIEDVHLW........
R1AB_CVHSA/182-423                   .v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW........
R1AB_CVHNL/111-315                   .s-VVFVDKYMCGFDGKPVLPKNMWEFRD...YFNNNTDS...........IVIGGVTYQLA.......WDVIRK.DLSYEQQNVLAIESIHYL....GTTGHTL..KSGCKLTNAKPPKYSSKVVLSGEWNAVYRAFGSPFITNgmslldiiVKPVFFNAFVKCN-CGSESWSVGAWD.GYLSSCCGTPA.KKLCV..-VPGNVVPGDV-..........................IITSTSAGC...GVKY...YAGLVVKHI......TNITGVSLW........
T2B9I2_9BETC/194-443                 ..DVTPVDQYMCGVDGKPISAYAFLMAKDgitKLADVEADvaara.ddegfITLKNNLYRLV.......WHVERK.DVPYPKQSIFTINSVVQKdgveNTPPHYF.tLGCKILTLTPRNKWSGVSDLSLKQKLLYTFYGKESLEN........PTYIYHSAFIECGSCGNDSWLTGNAIqGFACGCGASYTaNDVEV..QSSGMIKPNALLcatcpfakgdscssnckhsvaqlvsyLSERCNVIA..dSKSFtliFGGVAYAYF......GCEEGTMYF........
A0A1L2KGB4_9ALPC/111-315             ..DVVFVDNYMCGFDGKPVLPETIWEFKD...YFGDDVDN...........ITINGVSYQLA.......WDVTRK.PLSYKQQNVLAIESIRYL....GSKEHTL..RAGCKLFNAKQPKYSAKVVLSDEWIEVYKAFGSPFVTNgsslleilTKPVFFNAFVECN-CGNKGWSVGAWD.GYLSPCCGTPA.KKICV..-VPGNVVPGDV-..........................LVTSTNAGT...GTKY...YAGLVVKHV......VNVSGVSLW........
A0A088DIE1_9BETC/177-416             fh--RYVDNYYCTGDGKPLP-----CIVT...LLEKAGHAnkplddamdylRGLNRMGQPCRdhdhervWEVERD.NAPYPEQSLFSISAIKTL....GEIPHCVfaPDCAVKVMKPRKVKRGADGFMTKLRRVYNINGFDEV--........-KPMALCALHYCEDCGMEMWCHSNFE.EAYCPCGKIYT.NTPCT.lTSAGYVVEGSVVampcdacksdsd.hsngtfydsckylAEDKAEPGN...RENFv.yFGGCCFAYV......GCRNGNAIW........
U5LR11_9BETC/201-450                 ..DVIPVDQYMCGFDGSPIKPYLDLANKEgltKLADVEADvcsrv.dkqgfLIFKGTTYRVV.......WFTERK.DVDYSKQTLFTVICVMQRn.gvHDIPAHPftLGSKVEQLKPHVAKGNLVGLTLKAKILYTMYGEDAVEE........PSYIYHSAFVDCVKCNEGKWCTGNAVaGFACECGAAYTaKQVLL..QSSGLVKSNALFcatcpfaqgdrcsldckhtvpqvvsyLSEKCVVFP..sGKSFvlaFGGALYTYM......GCAEGTMYF........
S5YAF0_9ALPC/111-314                 ..NTIYVDQYLCGADGKPVVPEEFWDFKD...YFVDDDQ-...........VVVNGTTYIKA.......WVVERA.NVAYEAQNVTAINGITYC....AKIPHTL..PDGSVVRVARKPKIKKSIVLSDVYKPLLEGLGAPFVKNgdtlasilTEPVFLHALVKCT-CGKTMWTVGDWS.CYKSLCCGVVC.KPLCN..-VAGIVNPGSA-..........................VVTRTGLGS...GIKY...YCGMFLRHI......LDVDGVSVW........
A0A0U1WHD1_9ALPC/113-316             ep--VYVDNYMCGANGKPVLPADVWCFQD...YFGDETE-...........LVVNGVRHVKA.......WDVVRT.NLPYQFQSTGAIESIIWL....SDVPHVL..RNGSKLSVCKAPKFSKNVKLSEPLNTLYQACGSPFVSNgtdlagavGKPVFAHSYVACK-CGSKCWSVGDWS.GYKSTCCGTFG.KVLCT..-VFGDVVPGDV-..........................LMTSAAVGS...GTRY...YNGLTIKHV......VTVQNIACW........
Q0PL14_9ALPC/110-310                 .g-VIYVDQYMCGADGKPVIEG---DFKD...YFGDEDI-...........IEFEGEEYHCA.......WTTVRD.EKPLNQQTLFTIQEIQYN....LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDIKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQYA......GDVEGVSIW........
R9QTH2_CVHSA/182-423                 .v-TRYVDNNFCGPDGYPLE-----CIKD...LLARAGKSmctls.eqldfIESKRGVYCCReheheiaWFTERS.EKSYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSRVKVIQPRVEKKKTEGFMGRIRSVYPVASPGDCND........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEQCGTE-.NSVREgpTTCGYLPTNAVLkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RIKC...FGGCVFAYV......GCYNKRAYW........
A0A1L2KGB5_9ALPC/111-315             ..DVVFVDNYMCGFDGKPVLPETIWEFKD...YFGDDVDN...........ITINGVSYQLA.......WDVTRK.PLSYKQQNVLAIESIRYL....GSKEHTL..RAGCKLFNAKQPKYSAKVVLSDEWIEVYKAFGSPFVTNgsslleilTKPVFFNAFVECN-CGNKGWSVGAWD.GYLSPCCGTPA.KKICV..-VPGNVVPGDV-..........................LVTSTNAGT...GTKY...YAGLVVKHV......VNVSGVSLW........
U5KNA9_9BETC/201-450                 ..DVIPVDQYMCGFDGSPIKPYLDLANKEgltKLADVEADvcsrv.dkqgfLIFKGTTYRVV.......WFTERK.DVDYSKQTLFTVICVMQRn.gvHDIPAHPftLGSKVEQLKPHVAKGNLVGLTLKAKILYTMYGEDAVEE........PSYIYHSAFVDCVKCNEGKWCTGNAVaGFACECGAAYTaKQVLL..QSSGLVKSNALFcatcpfaqgdrcsldckhtvpqvvsyLSEKCVVFP..sGKSFvlaFGGALYTYM......GCAEGTMYF........
K4K1U5_9ALPC/111-315                 .t-TVFVDNFLCGANGLPACSEQEWEFKD...HFGELDE-...........VTINGTTFVKA.......WNVDRT.PGPYSTQNLLSINSISWC....GEIPHSL..ADGSIRRVAKVVKKSKSVLLGKQFQQLYDSVGSPFVTNgknlsdvlVKPIYCHALVKCQ-CGKTSWTVGDWS.CYKSMCCGFNC.KPLAI..-VNGEVVPGDV-..........................LVTSDKVSA..sGTKY...YNGMVLKFV......DKIDNACLW........
E0ZN43_BCHK9/191-395                 .l-VKPVQDLLGDIKPDLTLEKLTLALSD...YRKDDG--...........YDLPGGFVKIA.......VTVIRK.PVAVVKQTIFTVQGVVEQhvegYYYPYA-..PLGVVKQTKPAAGGPIGKTVEAIMLSLYGTSG------........YKPATPVARLKCSYCDHFGWTPLKDMgTVVCLCGAEYQlTSSCVdaESAGLIKPGCVM..........................LLDKSPGMRvipGNRTyvaFGGAIWSPI......GKVNDVTVW........
A0A059VJE6_9ALPC/111-316             .n-IVPVDQYMCGADGKPVLQESEWEYTD...FFADSEDG..........qLNIAGITYVKA.......WIVERS.DVSYASQNLTSIKSITYC....STYEHTF..PDGTAMKVARTPKIKKTVVLSEPLATIYREIGSPFVDNgsdarsiiKRPVFLHAFVKCK-CGSYHWTVGDWT.SYVSTCCGFKC.KPVLV..-ASCSATPGSV-..........................VVTRAGAGT...GVKY...YNNMFLRHV......ADIDGLAFW........
R9QTB2_CVHSA/182-423                 .v-TRYVDNNFCGPDGYPLE-----CIKD...LLARAGKSmctls.eqldyIESKRGVYCCReheheivWFTERS.DKSYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVATPQECND........---MHLSTLMKCNHCDEVSWQTCDFI.KATCEQCGTE-.NPVCEgpTTCGYLPTNAVVkmpcpacqdpevgpehsvadyhnhsnIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW........
A0A166ZL34_9NIDO/182-423             .v-TRYVDNNFCGPDGYPLD-----CIKD...LLARAGKSmctls.eqldfIESKRGVYCCReheheiaWYTERS.DKSYEHQTPFEVKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKNTEGFMGRIRSVYQVATPNECND........---MHLSVFMKCNHCDEASWQTCDFL.KATCEYCGTE-.NPVSEgpTTCGYLPTNAVVkmpcpacqnkevgpehsvadyhnhsnIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW........
D5HJV7_BCHK3/182-423                 .v-TRYVDNNFCGPDGYPLE-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCReheheivWFTERS.EKSYEHQTPFEIKSAKKFdtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVATPQECND........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEQCGTE-.NLVCEgpTTCGYLPTNAVVkmpcpacqdpevgpehsvadyhnhsnIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW........
R1A_BCHK4/196-440                    .d-CIPIDQYMCGKNGKPIADYAKIVAKEgltTLADIEVDvksrm.dsdrfIVLNKKLYRVV.......WNVTRR.NVPYPKQTAFTIVSVVQCd.dkDSVPEHTftIGSQILMVSP-LKATNNKNFNLKQRLLYTFYGKDAVQQ........PGYIYHSAYVDCNACGRGTWCTGNAIqGFACDCGANYSaNDVDL..QSSGLVPRNALFlancpcannga....cshsaaqvyniLDGKACVEV..gGKSFtltFGGVVYAYM......GCCDGTMYF........
R1AB_CVPPU/110-310                   ga--IYVDQYMCGADGKPVIEG---DFKD...YFGDEDI-...........IEFEGEEYHCA.......WTTVRD.EKPLNQQTLFTIQEIQYN....LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDIKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQYA......GDVEGVSIW........
A0A240FW17_9ALPC/111-292             .k-VVYVDNYLCGNNGKPVVPKDKWKIL-...--SKGQQG...........LLADNVYYKVV.......WDVKRD.DVPYEKQNMSSIVSIRYL....IDIPHFL..ADGAVREKKRPPQDYTTML----------VKGFPFLMA........YDWKFVNHAVKCGKCDNHVVEAGAFE.SVITSCCRDEI.VHQ--..-GVVTAKAGEL-..........................VLTPLSNKK...-LIL...VGSTVLRNI......GTAHNLSIW........
R1A_BCHK9/191-395                    .l-VEPVMKLLGVIKSDFTLEQLLAALGK...YRTEDG--...........YDLPDGYVKVA.......IKVGRK.AVPVLKQSIFTVVGVTEQlvpgYYYPFS-..TSSVVEHTKPTRGGPVGKTVEAVMLSLYGTNN------........YNPATPVARLKCSYCDYYGWTPLKDIgTVNCLCGAEFQlTSSCVdaESAGVIKPGCVM..........................LLDKSPGMRlipGNRTyvsFGGAIWSPI......GKVNGVTVW........
A0A0U1WHG1_9ALPC/109-313             ae--VYVDNYMCDQTGKPVLAADVWTFKD...YFGESDT-...........IVIDGVVYRKA.......WEVVRL.DVPYKAQSVSAISSIEWL....CGVQHVL..PSGTVLDVAKSVSKSKVVLLSDPYADIYDQVGSPFMTNgknlleivVKPCFLHGYVKCN-CGNTHWAVGDWRaGYKSVCCGLNC.NPICV..-AAGYVEPGDV-..........................LFTSKGAGT...GLKY...YKGLTLKFV......GEVENVAVW........
A0A172B3C8_9ALPC/111-312             .m-TVYVDQYMCGADGRPVISG---EMRD...YFGDLDD-...........IVIDGIIYSHA.......WDVERDlDVTHDKQTFLNIKSIMYL....QDKDHKL..PNGAIRVRAAPVKLSSKVVLSQPFADMYKHFGSPYMQNgdnlhgcfTKLNFIVANVKCK-CGGESSGVGDWT.GFKSACCGLPG.KVIGV..-SLGNAAVGEA-..........................VVTSKGCGN...GTKF...YANAVLKHV......GDADDVSIW........
#=GC seq_cons                        .s.shaVDpYhCGsDG+Plh.t..hphpD...ahu-ssp............IhlputhYpps.......WpVpRc.-lsYp+QohhsIpSIphh....s-hPHpl..hsusltplustsKtspshsLstphcpLYshhGsshhsN.........p.hahsAhlcCs.CGptoWssGDah.GapssCCGh.s.pslsl...osGhlhsGsl...........................lhTptssGs...Gs+a...FuGslhpal......GshsssuhW........
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