GenomeNet

Database: Pfam
Entry: Cortex-I_coil
LinkDB: Cortex-I_coil
Original site: Cortex-I_coil 
#=GF ID   Cortex-I_coil
#=GF AC   PF09304.11
#=GF DE   Cortexillin I, coiled coil
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1d7m
#=GF GA   26.20 26.20;
#=GF TC   26.20 26.30;
#=GF NC   25.90 25.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Coiled-coil
#=GF RN   [1]
#=GF RM   10745004
#=GF RT   The coiled-coil trigger site of the rod domain of cortexillin I
#=GF RT   unveils a distinct network of interhelical and intrahelical salt
#=GF RT   bridges. 
#=GF RA   Burkhard P, Kammerer RA, Steinmetz MO, Bourenkov GP, Aebi U; 
#=GF RL   Structure. 2000;8:223-230.
#=GF DR   INTERPRO; IPR015383;
#=GF DR   SO; 0001080; coiled_coil;
#=GF CC   Members of this family are predominantly found in the
#=GF CC   actin-bundling protein Cortexillin I from Dictyostelium
#=GF CC   discoideum. They adopt a structure consisting of an
#=GF CC   18-heptad-repeat alpha-helical coiled-coil, and are a
#=GF CC   prerequisite for the assembly of Cortexillin I [1].
#=GF SQ   11
#=GS A0A151ZH67_9MYCE/231-337  AC A0A151ZH67.1
#=GS F0ZQ22_DICPU/216-322      AC F0ZQ22.1
#=GS F4PG89_CAVFA/231-337      AC F4PG89.1
#=GS CTXA_POLPP/231-337        AC Q9Y0T4.1
#=GS F0Z9U7_DICPU/233-339      AC F0Z9U7.1
#=GS CTXA_DICDI/231-337        AC Q54HG2.1
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A B; 1-25;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A A; 1-25;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A K; 1-23;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A H; 1-21;
#=GS CTXA_DICDI/231-337        DR PDB; 1D7M A; 243-337;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A E; 1-22;
#=GS CTXA_DICDI/231-337        DR PDB; 1D7M B; 243-337;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A G; 3-25;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A L; 1-19;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A F; 1-21;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A D; 1-25;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A J; 1-25;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A I; 1-22;
#=GS CTXA_DICDI/231-337        DR PDB; 4J4A C; 1-25;
#=GS CTXB_POLPP/235-341        AC Q9Y0T3.1
#=GS A0A152A2Y5_9MYCE/235-341  AC A0A152A2Y5.1
#=GS CTXB_DICDI/233-339        AC Q550R2.1
#=GS F4QBP2_CAVFA/234-340      AC F4QBP2.1
#=GS R5E2S0_9FIRM/308-402      AC R5E2S0.1
A0A151ZH67_9MYCE/231-337             ...KEEKERLESSKNEIATRLAGLQNSLENEKVSREHLIKQQEEMKSLLASLEFEGAEREKRIKELEAKLDETLKNLELERLARLELEARLAKTEKDRAILELKLSDASD.................
F0ZQ22_DICPU/216-322                 ...KEEKERLESSKNEIANRLAGLQNSLENEKVSREQLIKQKDELKSLLASLEFEGAEREKRLRELEAKLEDTLKNLELEKLARMELEARLAKTEKDRAILELKLAEAT-e................
F4PG89_CAVFA/231-337                 ...KEEKERLEESKSAIASRLAGLQSSLENEKMSRELLIKQKEELKSLLASLEGEAASREHHLRELEAKLDEVLKNLELEKLARLELENRLAKTEKDKALLELALAEATD.................
CTXA_POLPP/231-337                   ...KEEKERLEASKSDLASKLAGLQNSLESEKLSREQLIKQKDELKSLLASLEGEAAEREKFLRELEAKLEEILKNLELERLARMELESRLSKMEKDKAILELKLAEAQD.................
F0Z9U7_DICPU/233-339                 ...KEEREALEASQNSLNNKLASLEQSLEGEKHSQEELLKQKQELENALNKIRSENENRNNRITDLQSRIDDALRGLDDEKLAKLDLESRLAKTEKDKAILELKLAEILD.................
CTXA_DICDI/231-337                   ...KEEKARLESSKNEMANRLAGLENSLESEKVSREQLIKQKDQLNSLLASLESEGAEREKRLRELEAKLDETLKNLELEKLARMELEARLAKTEKDRAILELKLAEAID.................
#=GR CTXA_DICDI/231-337        SS    ...XXXXXXXXXXXXXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH.................
CTXB_POLPP/235-341                   ...KEEREALEASQNSLANKLASLEQSLEGEKTSQDELARQKKELEESLRLIRQQNEQRNQRIADIQSKIDDALRGIDDEKMAKLDLESRLSKTEKDKAILELKLAETLD.................
A0A152A2Y5_9MYCE/235-341             ...KEEREALEASQNSLANKLASMEKSLEGEKLSQEELLKNKQQLESALNKIKNENEQRNHRISDLQSKIDDALRGLDDEKLAKLDLESRLAKTEKDKAILELKLAEILD.................
CTXB_DICDI/233-339                   ...KEEREALEASQNSLNNKLASLEQSLEGEKHSQEELVKQKKDLEDALNKIREQNDNRNSRITDLQSKIDDALRGLDDEKLAKLDLESRLAKCEKDKAILELKLAEILD.................
F4QBP2_CAVFA/234-340                 ...KEEREALEASQNSLQNTLSSLEGALQGEKLSQEELAKQKKDLENTLNELRAQNEARNKKISDIQARIDDALRGIDDERMAKLDLEARLSKTEKDKAILELKLQEMRD.................
R5E2S0_9FIRM/308-402                 aeq---IKTIEAGNRHFSERIADIDKDIEQKNKSLEDVINQKDALKDSLAEFEEKQAENDRKHEEITAQIEDISSKIDANQ-----------------------------nkiydilneksninadn
#=GC SS_cons                         ...XXXXXXXXXXXXXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH.................
#=GC seq_cons                        ...KEE+EtLEASpNslAN+LAuL-pSLEuEKhSpEcLlKQKc-LcshLsplctEsspRp+Rlp-LpAKlDDsL+sL-.EKLA+L-LEuRLAKTEKDKAILELKLAEhhD.................
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