GenomeNet

Database: Pfam
Entry: CzcE
LinkDB: CzcE
Original site: CzcE 
#=GF ID   CzcE
#=GF AC   PF16986.6
#=GF DE   Heavy-metal resistance protein CzcE
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   PDB:2wtp
#=GF GA   30.00 30.00;
#=GF TC   30.60 34.50;
#=GF NC   28.90 25.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   15340798
#=GF RT   Identification of a regulatory pathway that controls the
#=GF RT   heavy-metal resistance system Czc via promoter czcNp in
#=GF RT   Ralstonia metallidurans.
#=GF RA   Grosse C, Anton A, Hoffmann T, Franke S, Schleuder G, Nies DH;
#=GF RL   Arch Microbiol. 2004;182:109-118.
#=GF RN   [2]
#=GF RM   18029263
#=GF RT   CzcE from Cupriavidus metallidurans CH34 is a copper-binding
#=GF RT   protein.
#=GF RA   Zoropogui A, Gambarelli S, Coves J;
#=GF RL   Biochem Biophys Res Commun. 2008;365:735-739.
#=GF RN   [3]
#=GF RM   20112954
#=GF RT   Evidence for conformational changes upon copper binding to
#=GF RT   Cupriavidus metallidurans CzcE.
#=GF RA   Petit-Haertlein I, Girard E, Sarret G, Hazemann JL, Gourhant P,
#=GF RA   Kahn R, Coves J;
#=GF RL   Biochemistry. 2010;49:1913-1922.
#=GF DR   INTERPRO; IPR031560;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   CzcE is involved in heavy-metal resistance [1]. It binds copper
#=GF CC   [2], which induces a conformational change [3].
#=GF SQ   92
#=GS A0A254NA58_9BURK/6-83     AC A0A254NA58.1
#=GS Q1LAJ1_CUPMC/51-131       AC Q1LAJ1.1
#=GS Q1LAJ1_CUPMC/51-131       DR PDB; 2WTO B; 26-104;
#=GS Q1LAJ1_CUPMC/51-131       DR PDB; 2WTP B; 26-104;
#=GS Q1LAJ1_CUPMC/51-131       DR PDB; 2WTO A; 26-105;
#=GS Q1LAJ1_CUPMC/51-131       DR PDB; 2WTP A; 26-105;
#=GS G8QK51_AZOOP/53-128       AC G8QK51.1
#=GS A0A3A3FU03_9BURK/30-110   AC A0A3A3FU03.1
#=GS A9BT07_DELAS/28-105       AC A9BT07.1
#=GS L9PA21_9BURK/33-113       AC L9PA21.1
#=GS A0A418X6F7_9BURK/31-111   AC A0A418X6F7.1
#=GS A0A011MPH4_9PROT/1-45     AC A0A011MPH4.1
#=GS W0V485_9BURK/35-115       AC W0V485.1
#=GS B2UF17_RALPJ/87-167       AC B2UF17.1
#=GS A0A0Q5HZV0_9BURK/11-91    AC A0A0Q5HZV0.1
#=GS A9BRK8_DELAS/28-105       AC A9BRK8.1
#=GS A0A0Q7AJD9_9BURK/371-448  AC A0A0Q7AJD9.1
#=GS A0A328ZHW6_9BURK/74-152   AC A0A328ZHW6.1
#=GS D0IXY8_COMT2/53-132       AC D0IXY8.1
#=GS C4K940_THASP/53-128       AC C4K940.1
#=GS A0A1C9VBA0_9BURK/141-207  AC A0A1C9VBA0.1
#=GS A4GA65_HERAR/28-108       AC A4GA65.1
#=GS A0A0K1J4X2_9RHOO/52-127   AC A0A0K1J4X2.1
#=GS A0A3A3G4B0_9BURK/30-110   AC A0A3A3G4B0.1
#=GS C7RVW5_ACCPU/53-128       AC C7RVW5.1
#=GS A0A0K8NVF0_IDESA/1-72     AC A0A0K8NVF0.1
#=GS W0V4Q7_9BURK/33-113       AC W0V4Q7.1
#=GS A0A238D672_THIDL/26-106   AC A0A238D672.1
#=GS A0A3N7BP74_9BURK/5-83     AC A0A3N7BP74.1
#=GS S9ZK77_9RHOO/31-106       AC S9ZK77.1
#=GS Q47DR1_DECAR/53-128       AC Q47DR1.1
#=GS B2UEC2_RALPJ/49-129       AC B2UEC2.1
#=GS Q58AE5_CUPMC/71-151       AC Q58AE5.1
#=GS A0A239LKA6_9BURK/31-110   AC A0A239LKA6.1
#=GS A0A1S9AC37_9BURK/26-102   AC A0A1S9AC37.1
#=GS A0A238DWM3_9BURK/26-104   AC A0A238DWM3.1
#=GS A0A208XLN0_9BURK/29-107   AC A0A208XLN0.1
#=GS A0A1H5YVM1_9RHOO/31-107   AC A0A1H5YVM1.1
#=GS A0A1S9A6J8_9BURK/80-160   AC A0A1S9A6J8.1
#=GS A0A1A8XYV7_9PROT/58-133   AC A0A1A8XYV7.1
#=GS A0A0F0FUF9_9BURK/46-126   AC A0A0F0FUF9.1
#=GS A0A0L6VX70_9BURK/37-114   AC A0A0L6VX70.1
#=GS B2UF38_RALPJ/45-127       AC B2UF38.1
#=GS A0A0C1Y3W2_9BURK/28-107   AC A0A0C1Y3W2.1
#=GS A0A1B4XER7_9GAMM/32-112   AC A0A1B4XER7.1
#=GS A0A1A8Y221_9RHOO/57-132   AC A0A1A8Y221.1
#=GS C7RVY2_ACCPU/53-128       AC C7RVY2.1
#=GS A6T3W6_JANMA/28-108       AC A6T3W6.1
#=GS A0A1D9GY89_9BURK/39-119   AC A0A1D9GY89.1
#=GS A0A0U3D8E6_9BURK/35-114   AC A0A0U3D8E6.1
#=GS A0A254NHM3_9BURK/6-83     AC A0A254NHM3.1
#=GS A0A418Y6S3_9BURK/30-110   AC A0A418Y6S3.1
#=GS A0A2S9GZX7_9BURK/30-109   AC A0A2S9GZX7.1
#=GS A0A254TAK7_9BURK/27-107   AC A0A254TAK7.1
#=GS A0A0N0XFY9_9NEIS/30-107   AC A0A0N0XFY9.1
#=GS A0A0A0DJX3_9BURK/37-118   AC A0A0A0DJX3.1
#=GS A0A0J1D8D1_9BURK/29-112   AC A0A0J1D8D1.1
#=GS A0A2U8FQW2_9BURK/31-112   AC A0A2U8FQW2.1
#=GS F1W2C5_9BURK/28-108       AC F1W2C5.1
#=GS A0A3R8T894_9BURK/34-114   AC A0A3R8T894.1
#=GS A0A1D9HD87_9BURK/49-129   AC A0A1D9HD87.1
#=GS A0A239F4D4_9BURK/32-105   AC A0A239F4D4.1
#=GS A0A0C4Y935_9BURK/39-119   AC A0A0C4Y935.1
#=GS A0A1D9H9L5_9BURK/1-65     AC A0A1D9H9L5.1
#=GS A0A1I6KNB4_9BURK/35-113   AC A0A1I6KNB4.1
#=GS A0A1M5M4J3_9BURK/30-110   AC A0A1M5M4J3.1
#=GS N6XB98_9RHOO/53-128       AC N6XB98.1
#=GS A0A1I6KNF0_9BURK/34-111   AC A0A1I6KNF0.1
#=GS A0A1S9A8I1_9BURK/28-108   AC A0A1S9A8I1.1
#=GS W0V4L6_9BURK/30-110       AC W0V4L6.1
#=GS G8QNT3_AZOOP/53-128       AC G8QNT3.1
#=GS A0A2T6F1K1_9BURK/28-108   AC A0A2T6F1K1.1
#=GS A0A239I7J9_9BURK/31-110   AC A0A239I7J9.1
#=GS A0A1H5YKB1_9RHOO/53-128   AC A0A1H5YKB1.1
#=GS A0A0Q8QKT7_9BURK/29-109   AC A0A0Q8QKT7.1
#=GS S9ZK71_9RHOO/53-128       AC S9ZK71.1
#=GS A0A257FPD7_9BURK/11-89    AC A0A257FPD7.1
#=GS Q1LBG1_CUPMC/76-156       AC Q1LBG1.1
#=GS A0A098U3Q4_9BURK/25-106   AC A0A098U3Q4.1
#=GS A0A1B4V6K3_9GAMM/43-120   AC A0A1B4V6K3.1
#=GS A0A1A8XW62_9PROT/1-65     AC A0A1A8XW62.1
#=GS B2UC49_RALPJ/55-134       AC B2UC49.1
#=GS A0A0M2WS03_9BURK/33-113   AC A0A0M2WS03.1
#=GS W0V0H0_9BURK/30-110       AC W0V0H0.1
#=GS A0A254MYE8_9BURK/34-112   AC A0A254MYE8.1
#=GS A0A1C7AF02_9GAMM/33-113   AC A0A1C7AF02.1
#=GS A0A4U8V3E1_9BURK/73-153   AC A0A4U8V3E1.1
#=GS A0A1A8Y224_9RHOO/53-128   AC A0A1A8Y224.1
#=GS A0A2S5SWM8_9BURK/34-113   AC A0A2S5SWM8.1
#=GS W0V7Q9_9BURK/30-110       AC W0V7Q9.1
#=GS A0A0Q8NXX9_9BURK/30-111   AC A0A0Q8NXX9.1
#=GS A0A1S9AA11_9BURK/16-95    AC A0A1S9AA11.1
#=GS A0A437LQX5_9BURK/36-114   AC A0A437LQX5.1
#=GS W0V7R2_9BURK/35-115       AC W0V7R2.1
#=GS W0V8G5_9BURK/16-96        AC W0V8G5.1
#=GS A0A2U8FY58_9BURK/1-73     AC A0A2U8FY58.1
A0A254NA58_9BURK/6-83                ......sv--HGEA.V.AAP..QNARIVNLDAG-K.SVNVKCGEVITFQ.K....A.G.KSFSWKFDSA-..QHRAVDVRTIAPAG.F.ADKPLMVYVSRSEW--e....
Q1LAJ1_CUPMC/51-131                  .......t-LYGDP.A.GQS..QASRIIDVKPGMR.YVNVDSGETVAFR.A....G.E.KIVAWTFAQMV..RDTSVDLGLLMPDL.P.GSAGVRVYIDRSDLF-t....
#=GR Q1LAJ1_CUPMC/51-131       SS    .......H-CCEEE.E.-GG..G-SEEEE--TT--.EEEEETT-EEEEE.E....T.T.EEEEEEE--BS..S-EEEEHHHH-TTS.T.T-TT-EEEEEB-TT--X....
G8QK51_AZOOP/53-128                  .......a-AFGY-.A.ATK..SADREITVDSGTK.HVNVTRLETVKIN.V....G.G.KTVVWTFDTL-..GTAAFPLSKIMP--.-.GADGITVYVAENPSYQ.....
A0A3A3FU03_9BURK/30-110              .......d-LYGMP.A.DPR..AAIRTINIFPTTN.YVNVEGGEIIRFV.S....G.N.QEFGWHFLVAR..TVNSFSLNEVAPPG.A.LNRPVEAYVSPDPRY-i....
A9BT07_DELAS/28-105                  .......k-SYYGS.E.VQS..PNFRTIDLSQK-K.PININCGEIIQFS.S....N.G.KTFIWKADSI-..YHSEVPIAKFAPKG.F.DAQGRSMFVAPNE-Y-e....
L9PA21_9BURK/33-113                  .......p-AFGSA.A.PAP..AATRTMVISAATK.AVNVDKGDVVTFE.L....E.G.KTFTWQFDTLR..DSDRFELSAIAPEG.V.NTHGVRVYVAPNPLYR.....
A0A418X6F7_9BURK/31-111              .......k-LLGDP.A.PAS..SGTRTIVITPDTR.HVNVTGGEVVNFA.V....G.D.KMFTWSFFVAA..GISSFDLNRIAPPG.M.LDHVVTAYVARDPRY-i....
A0A011MPH4_9PROT/1-45                .......m------.-.---..-------------.----------QID.V....G.G.KSITWKFDTF-..GTAPFPLSRIVP--.-.GAEGITVYVAENPA--nq...
W0V485_9BURK/35-115                  .......a-DYGMQ.V.APD..TPAREVTIDAQTR.SVNVEDGETVKFN.V....N.G.KSFVWHFATFS..EAGNVKLSRIAPAG.I.DVKRVTAYIDSNPLYR.....
B2UF17_RALPJ/87-167                  .......p-LFGER.A.TTA..VGARTVVIAPGMK.AVPVLAGETVRFD.F....G.Q.SSAAWTFAARP..GSSAVELSMLFPEI.P.AAKGIWAYPNGTGMY-a....
A0A0Q5HZV0_9BURK/11-91               .......d-LLGTP.V.PAS..AATRTVNLSPNMH.SINVVAGDTIRFV.N....G.S.GEFGWSFDVSP..LVQVFDLNQVAPSG.A.LGHPLRVYVAPNPLY-s....
A9BRK8_DELAS/28-105                  .......k-SYYGS.P.APA..GVYRTVDLSQK-G.PINIACGETVNFT.S....Q.G.RTFAWKVSSI-..QHNHVPVARFAPPG.F.DTQGKSIFVMPGE---he...
A0A0Q7AJD9_9BURK/371-448             .......e-LFGSP.A.PVS..LVTRTIAIGPGTS.YVNVTGGEVIRFD.V....G.D.KSFVWNFNGQ-..-RSSFDLAKVAPPG.V.LARKVTAYVAPNPM--q....
A0A328ZHW6_9BURK/74-152              ......sa--LGRA.A.SPA..NATRTVDASQA-R.TLNVKCGETVAFR.N....G.D.KTFAWKFDVA-..AHRPVSLAAISPSD.F.GASPLRVYVAPNE---ger..
D0IXY8_COMT2/53-132                  .......r-TFGRA.G.AES..QVSRVVDTTRSTQ.YLNLVCGETVEFT.N....G.K.EQFIWKFDVM-..GHRPVDLSKIAPAA.F.AGSTLKIYVAKNELER.....
C4K940_THASP/53-128                  ........ATYGY-.A.SNA..TPSRTVIVNADTR.YINVTRLETVALK.V....G.D.KTVNWTFDTI-..GTNSFPLSKVIQ--.-.GGDKVTVYLEESPLYR.....
A0A1C9VBA0_9BURK/141-207             ......wl------.-.---..-----IDVSAT-K.YANITYGETVVFQgV....G.G.QKFAWTFNGL-..DGRSWDLAKFAPAG.L.AGKDYRVYVTKNPL--tr...
A4GA65_HERAR/28-108                  .......d-PLGNP.A.PAA..AATRTIVITPETR.WVNVEGGEVIRFI.V....G.D.KSFGWDFYVGS..TVTSFDLQLVAPPG.V.LNRRIVAYVSTDPRYR.....
A0A0K1J4X2_9RHOO/52-127              .......a-RYGY-.A.SLA..TAERSITIDNQTR.HINVVRMETIAIR.V....G.E.KTVTWTFDTL-..GTSSFPLSEIIP--.-.GTEQVTVYVDENPMYR.....
A0A3A3G4B0_9BURK/30-110              .......d-LLGER.A.PEA..AAQRTVVITPATR.HVRVEGGEIVKFV.V....G.D.RAFTWQFNGPP..TTEVVKLNRIVPPG.V.LDQKVTAYVDPDPRY-l....
C7RVW5_ACCPU/53-128                  ........APFGY-.A.ATK..NADREVSLPSGGK.YLNVTRLETLKLN.V....D.G.KSVVWTFDTL-..GTAAFPLSTIVP--.-.GADGITVYVRENPAYQ.....
A0A0K8NVF0_IDESA/1-72                .......m------.-.--S..SAARVVDLAQAPR.P-NIAYGETVAFR.G....DaG.QQFAWTFNGL-..DRRGVDLAKIAPPG.F.GAKSAIAYVGRDP---snr..
W0V4Q7_9BURK/33-113                  .......q-AFGST.A.PAV..AATRTVLISPATK.AVNVDNGDVVTFE.V....D.G.KTFTWQFGTLR..DSERFELSAIAPEG.V.HTHGVRIYVAQNPLYR.....
A0A238D672_THIDL/26-106              .......r-LLGTP.V.PDS..VASRVVTITPNTD.SINAKWGHSIEFK.D....H.G.KSFAYEFDGPH.aDDARVNLERLAPAG.M.INHPVYAYVAGSP---vn...
A0A3N7BP74_9BURK/5-83                .......s-IYGVP.A.TAS..SAVKEVNVDQL-D.ALNVKCGDTLTFR.Q....G.A.QSFTWKFDVV-..SHRIVDLQKIAPAG.F.IKKPLLVYVDRNESE-r....
S9ZK77_9RHOO/31-106                  .......a-AYGY-.T.SNA..TPSRTITVNASTR.HINVTRLETVALK.V....G.D.KTVNWTFDTL-..GKNSFPLSKIVP--.-.GADKVTVYLEENPLY-s....
Q47DR1_DECAR/53-128                  ........APYGY-.A.ASG..TAAREVIIDSGTK.YLNVTRLETIRIN.V....G.G.KSVTWMFDTL-..GTASFPLANIIP--.-.GAGDVTVYVTENPAYR.....
B2UEC2_RALPJ/49-129                  .......t-LYGDP.A.GQS..QASRIIDVKPGMR.YVNVDSGETVAFR.A....G.E.KIVAWTFAQMV..RDTSVDLGLLMPDL.P.GSAGVRVYIDRSDLF-t....
Q58AE5_CUPMC/71-151                  .......s-LFGSE.A.PAG..STSRVVDVAPGLK.YVNVDSGETVTFK.S....G.A.SEITFAFAQLD..RNKAVALNVLFPEL.P.GGQGVWVYIEQSELY-i....
A0A239LKA6_9BURK/31-110              ......df--YGAP.A.AVS..QINRTIAIHPDTR.WVNAEGGETINFV.T....P.G.GTFAWQFFAT-..APRRFDLNFVAPPG.M.LDHRVEAFISPDRRY-i....
A0A1S9AC37_9BURK/26-102              adhgavvq------.-.-DA..GAVRKIVIQPNTK.SVTVQDGETVTFV.V....D.G.KSFSYHFQTWP..TTNVLPLSAIAPQE.V.NVGGVRVYVN------hl...
A0A238DWM3_9BURK/26-104              .......r-LFGTP.V.PDS..VASRVVAITPSTD.SINAQWGRSIEFK.D....H.G.KSFAYEFDGPR..ADARVNLERVAPAG.M.INHPVYAYV-------ggfpv
A0A208XLN0_9BURK/29-107              .......n-LLGSQ.V.TVE..SAERAIALDDSTR.YVNVRFGETVRFD.V....N.G.KSFAVKFDGI-..-RGSFDLNALAPAG.V.LNHPVKAYVSPSPL--de...
A0A1H5YVM1_9RHOO/31-107              .......a-AYGY-.T.SNA..TPSRTITVNASTR.HINVTRLETVALK.V....G.DnKTVTWTFDTL-..GKNSFPLSKIVP--.-.GADQVTVYLEESPLY-s....
A0A1S9A6J8_9BURK/80-160              .......a-DYGTP.A.AAT..SSARQVDIKPGTR.NVNVYDGETVQFV.V....D.G.KRIGWNFNTRT..REAVLDLNTIAPEL.V.QQGAVRVWVLPNPIY-f....
A0A1A8XYV7_9PROT/58-133              ........APYGY-.V.ASG..VAGRVFNVDSGTK.HINVSRLETVRID.V....G.G.KSVTWKFDTL-..GTAPFPLSKIIS--.-.GADGVTVYVAENPA--sq...
A0A0F0FUF9_9BURK/46-126              ........ALFGSP.A.DVT..TTTRTVTLTPGMN.YVNVASGESVAFR.A....G.N.KTVGWTFLEAI..GGTSVDMKTIFPNV.A.QAGGIRVYIAPSKLF-t....
A0A0L6VX70_9BURK/37-114              ......iv------.P.AQS..PADEVIVITDGTR.YVNVTGGTTVRFL.S....N.G.QAFTWSFQTGG.aRIMPFDLGRIAPRG.F.LNHRVVTYVADDPLY-l....
B2UF38_RALPJ/45-127                  ........AQFGHP.A.AIA..HASRTITLTPRIR.YVHVYVGETVAFQ.I....G.E.KKIGWMFTAPTigGGQPIDMSSIFPDI.P.EAKGIVIFIERSNLYR.....
A0A0C1Y3W2_9BURK/28-107              .......f--LGDP.A.PLN..GATETIAIRPDTK.WINVTGGDTVRFV.V....G.E.KSFAWTFNVAR..NVTAFDLRRVAPPG.V.LDHRVDAYVAPDPKY-l....
A0A1B4XER7_9GAMM/32-112              .....pnl---GTP.V.HDE..SADRTIVLDAGAK.WANVTGGETIRFV.V....G.G.KSFSWRFDTFN..TSPVFDLDKIAPAGmL.DGRSIKVYVSPDP---qq...
A0A1A8Y221_9RHOO/57-132              ........APYGY-.A.TSG..TAARVVNIDGGTK.HLNVTRLESVRII.V....G.G.KSVTWMFDTL-..GTSSFPLSKVIP--.-.GADGVTVYVTENPSY-s....
C7RVY2_ACCPU/53-128                  ........APFGY-.A.ATK..NADREVSLPSGGK.YFNVTRLETLKLN.V....G.G.KSVVWTFDTL-..GTAAFPLSKIVP--.-.EADGITVYLTENHFYQ.....
A6T3W6_JANMA/28-108                  .......d-LLGYP.A.TAA..AAVRTIVITPDTK.WVNVEGGEIINFV.V....G.D.KSFAWHFYVGF..TVNSFDLQLVAPPG.L.LQRRIVAYVSPDPMY-i....
A0A1D9GY89_9BURK/39-119              .......r-LFGSP.A.RLD..TVTRTIDVTPGTR.RVLVGSGESVAIR.A....G.G.QTVGWTFLQAI..GGSSMKLALLMPGV.P.QAKDVYIQIAPSEIY-s....
A0A0U3D8E6_9BURK/35-114              .......s-VYGVP.A.QAT..AASKVIDVTKAAQ.QINLKCGEVVSFR.N....G.D.KSFTWKFDSV-..GHAAVDLAAIAPAG.F.AGAGIKVYVERNE---ger..
A0A254NHM3_9BURK/6-83                .....svh---GEA.V.TAT..QGARVVKVDAG-K.AINVNCGDVVTFQ.S....A.G.KSFTWKFSSA-..SHRALDVRDIAPQG.F.TDKKLMVYVSRAD---se...
A0A418Y6S3_9BURK/30-110              .......e-LLGDP.A.PTA..AATQAIVITPETR.WVNVTGGETVKFI.V....G.D.KEFAWNFTVAP..SISSFALNRVAPAG.I.MTRNVVAYVAPDPHY-l....
A0A2S9GZX7_9BURK/30-109              ......sf--WGDP.A.SIS..FADRTIIIYQNTS.YVNVTGGEIIKFI.V....G.N.KSFSWHFNGA-..GQYNFDLMLVAPQG.M.LDHRVMAYVESDPRF-a....
A0A254TAK7_9BURK/27-107              ......gl--LGDP.A.PVE..AATQTIVISPQTK.WVNVTGGDIVRFD.V....G.D.KSFAWAFNVGT..GISRFDLSRVAPPG.V.LGRTLYVYMAPDPRY-i....
A0A0N0XFY9_9NEIS/30-107              ......la--YGSP.V.AENttQPVRQINLNNG-Q.SVDVQKGEVVELV.S....G.S.AHEEWKFDGV-..-QPEFTLAHVFPAA.D.HANSIRVYVAD-----pdh..
A0A0A0DJX3_9BURK/37-118              ....mtht------.P.APV..QADRTIDITPQTQ.WVNVKRLEVVQFV.SqvngN.T.RTFTWQAPAH-..ALKPFSLSDIAPSD.F.AAQPITVYVAPSRL--sr...
A0A0J1D8D1_9BURK/29-112              adfrgnaa------.P.AQA..PVDQVIVITDATR.HVNVTGGTTVRFV.V....G.D.QSFSWSFQNGS.aHVVPFDLALIAPKG.L.LNHPVTAYVSDNPLYQ.....
A0A2U8FQW2_9BURK/31-112              .......s-IFGTP.A.STA..EVERTIEILPTTR.WINVTRFETVRLA.IrdgnE.T.KYVIWRFDTL-..SFTPFDLSQAIP-S.L.GARSIKVFVGASH---ld...
F1W2C5_9BURK/28-108                  .......k-LLGMA.A.PPE..AAIKTIVLTPETA.HVNVTGGEVIRFV.A....G.N.KTFAWSFDGPL..QVSRVDLMRVAPPG.F.LDHPVIAYIAPNPMY-l....
A0A3R8T894_9BURK/34-114              dsygvavs------.-.STT..AATKTVDVSSLKRpYINVRCGDVVVFR.N....G.D.RSFTWKFDVK-..GHRTFDLAKVAPQG.F.VTSPLKVYVAGNDL--e....
A0A1D9HD87_9BURK/49-129              .......t-LYGDP.A.GQS..QASRIIDVKPGMR.YVNVDSGETVAFR.A....G.E.KIVAWTFAQMV..RDTSVDLGLLMPDL.P.GSAGVRVYIDRSDLF-t....
A0A239F4D4_9BURK/32-105              ...dspsn------.-.---..SAMYALELTPATR.TVNVALGDHVTFV.S....G.G.RSFVYSFDDP-..NYWPVQLDRVLPPG.M.VDHQVTAYVSP-----yrkf.
A0A0C4Y935_9BURK/39-119              ........ALFGSP.A.DVS..TTTRTVTLVPGMN.YVNAASGESVAFR.A....G.D.KTVGWTFLEAI..GGTSVDMRTIFPAM.A.QARGIRVYIAPSQLF-t....
A0A1D9H9L5_9BURK/1-65                .......m------.-.---..-------VAPRQR.NIDVEAGESVAFR.F....G.T.QKAAWAFAPCF..GAGALERVRKFSGI.P.AALGIWMRIRPGSMF-s....
A0A1I6KNB4_9BURK/35-113              ......si--YGVP.F.AGQ..KTDFVVDLDSR-K.AINIECGQTVQFR.Q....G.G.KTFAWKFDVV-..GHRAVDLSKIAPAG.F.SSKPFKVYVDKNE---ger..
A0A1M5M4J3_9BURK/30-110              .......a-DYGVP.V.TDG..ASGRVIRISAATK.YVHVTNGEAVTFE.F....D.G.QRFGWQVSTYS..NVNEFALKQILPPG.T.QLPAVRVIVAPNPLY-l....
N6XB98_9RHOO/53-128                  ........ATYGY-.A.SNA..TPSRTVIVNADTR.YINVTRLETVALK.V....G.D.KTVNWTFDTL-..GTNSFPLSKVVQ--.-.GGDKVTVYLEESPLYR.....
A0A1I6KNF0_9BURK/34-111              ......sp--HGLP.V.AAV..KADKVVDVKQG-G.FVNVDCGQIVEFR.D....G.A.KTFTWKFDSA-..QHRAVNLPVIAPEG.F.ANANFTVYVSRNE---se...
A0A1S9A8I1_9BURK/28-108              .......n-DFGQR.V.AEA..KGTRVITVKPGAK.HVNVTNGETVTFD.V....N.G.QRFSFDVNTYP..NQNVFQLSDIAPAG.V.QADGVKVYVAANPLY-f....
W0V4L6_9BURK/30-110                  ......pa--LGHA.V.PAS..AATRTVTISSATE.HVNVNQEDVVKFE.A....D.G.KSFTWQFDTLR..SDERFDLAAIAPAD.V.HVKNVRVYVAPNPIY-s....
G8QNT3_AZOOP/53-128                  ........APYGY-.A.ASR..NADREVTLSSGSK.YLNVTRLETIKIN.L....G.G.KSVVWTFDTL-..GTASFPLSKIVS--.-.GADGITVYVTENPAYQ.....
A0A2T6F1K1_9BURK/28-108              .......d-LLGDA.M.PAS..AATRTIVITPSTK.FVNVTGGERVRFV.A....G.D.KTFGWNFDGAL..QVTSFDLNRIVPAN.V.LDHEVVAYVTPNPTY-v....
A0A239I7J9_9BURK/31-110              ......df--YGAP.A.AAY..PTQRTVVITPATR.YVNVEGGETINFA.I....G.D.KSFAWQFFAT-..APRRFDLNFIAPPG.L.LDHRVEAFVSPDPRY-i....
A0A1H5YKB1_9RHOO/53-128              ........ATYGY-.A.SNA..TPSRTVIVNADTR.YINVTRLETVALK.V....G.D.KTVNWTFDTL-..GTNSFPLSKVVQ--.-.GGDKVTVYLEESPLYR.....
A0A0Q8QKT7_9BURK/29-109              .......d-LLGMS.A.PDA..AATRTIAITPGTR.YVNVTGGDIVTFV.V....G.E.KTFTWNFLLPI..GMSSFELNRVAPPG.L.LDHTVTAYVAPDPRY-m....
S9ZK71_9RHOO/53-128                  ........ATYGY-.A.SNA..TPSRTVIVNADTR.YINVTRLETVALK.V....G.D.KTVNWTFDTL-..GTNSFPLSKVIQ--.-.GGDKVTVYLEESPLYR.....
A0A257FPD7_9BURK/11-89               .......s-VYGAA.A.SAS..QAAKVVDVGAA-S.TLNIDCGETVTFR.N....G.D.KSFSWKFDVI-..GHRAVDLQAIAPAG.F.SSKPLKVYVARNDSE-r....
Q1LBG1_CUPMC/76-156                  ........ALFGSQ.A.ALD..TVTRTIDVAPGMK.RLTVASGESVAIR.A....G.G.RTVGWTFLQSI..NGSAMNLAVLMPGV.P.QARDVYVFIEPSEIYR.....
A0A098U3Q4_9BURK/25-106              .......d-TYGTV.ApATA..NAGRVIDVTPTTR.YVNVANGETVTIR.L....G.G.DSFTWTVATKS..NVDAVPLARVAPEG.S.PATAAVVYVAPGASYH.....
A0A1B4V6K3_9GAMM/43-120              ....arpq------.-.-AR..GADRTIAIGADTK.HVNVEGGEIVRFT.V....G.G.NAFEWLFDTYG..TGRVFDLKEIAPAGtL.DGRDIKVYVSPDPLY-s....
A0A1A8XW62_9PROT/1-65                .......m------.-.---..---RVLSVDSGSS.YRKGTRLETVQVD.L....D.G.RSITWTLDTF-..GTTSSPLSKNVA--.-.VAEGITVHMTEHRAYR.....
B2UC49_RALPJ/55-134                  .......l-LFGSP.A.PVS..LAARTLTVKPGMK.YINVESGETVAFS.A....G.T.GTQAWTFIEAM..QSTSVDLGVLLPDV.P.DAKGVRVIIARSKW--l....
A0A0M2WS03_9BURK/33-113              .......a-DYGSS.A.PHA..AAQRSIELQPDTR.HINVTRGETVTIA.R....A.G.QRFTWHVQTFN..HQTTFALVEIAPKD.M.AVDGVQVYVAANPLY-a....
W0V0H0_9BURK/30-110                  .......d-DYGVA.A.APN..TAGRTISVQPGAK.YLNVTNGETVNIS.I....A.G.KNFAWNVNTFP..SKTVFDLSEIAPKD.V.PADGIKVYVADNPLY-s....
A0A254MYE8_9BURK/34-112              ......sw--YGGP.N.SAE..QATRVVDVNSV-E.AINAKCGDTITFR.N....G.D.KTFTWRFDVV-..SHRAVDFRKVAPAG.F.ASKELVVYVSRNDTE-r....
A0A1C7AF02_9GAMM/33-113              .....psl---GTA.I.HSA..AADRTVVLEPGAK.WVNVNRNETVKFV.L....G.D.QSFTWRFDTL-..NQSVIELDKIAPAG.LrGTSGIKVYVGPDPM--he...
A0A4U8V3E1_9BURK/73-153              .......s-LYGRP.A.TVA..EATRTIDLAQAGG.WINLESGETVAFR.S....G.D.RIAAWSFAPAV..RHRTVQLSQLLPDL.P.QANTVRLNLERASLYR.....
A0A1A8Y224_9RHOO/53-128              ........APYGY-.A.STG..TAARSVNVDRSTK.YLNVTRLETVKVN.V....D.G.KSVIWMFDTL-..GTNAFPLSKIVS--.-.GTEGVTVYVAENPRYR.....
A0A2S5SWM8_9BURK/34-113              .......s-IYGQP.A.AAS..SAARVVDLAQVAR.P-NIAYGETVIFL.G....DaG.QQFAWTFNGL-..DRRGVDLAKIAPAG.F.ATKGAVAYVARDPA--nr...
W0V7Q9_9BURK/30-110                  ........APYGSA.A.PAS..AAQRQVSITPDTA.SVNVSNGETVEFK.L....N.G.GSFTYHFATLR..REASFDLAQIAPAG.A.ASGKVTVYVAANPLY-a....
A0A0Q8NXX9_9BURK/30-111              .......d-LYGREiP.PAA..WVDRTMVLTPETR.YINVEGGQSVRFI.V....G.D.KAFAWHFIVAR..TVDAFDLKEVAPAG.L.LDHTVMAYVSPDPKY-l....
A0A1S9AA11_9BURK/16-95               ...aavah-----A.A.DHA..APARLLHVTPHTR.HLSVTEGETVSIR.V....G.G.ATYTRLIAAPR..GVRAFSLSELVPAA.I.ALGEIRVLVAPA----rrq..
A0A437LQX5_9BURK/36-114              .......s-HFGAA.S.TSE..QATKVVDVRNT-K.YINLVCGETVTFR.N....G.D.QSFSWRFDVV-..NHRTVDARKVAPAG.F.MTEPLMVYVRPNAY--er...
W0V7R2_9BURK/35-115                  .......a-DFGSL.V.APD..TPAREITIDANTK.SVNVTDGETVKFN.V....N.G.KSFVWRFDTYH..DAFNVKLSLLAPNS.I.NVDGVTAYISSNSLYR.....
W0V8G5_9BURK/16-96                   .......a-DFGSL.V.SDS..TPARQITIDAQTR.SVNVKDGETVKFN.V....G.G.KSFVWHFETFH..DALDVDLSLIAPAG.I.KVDGIVAYIAANPLYR.....
A0A2U8FY58_9BURK/1-73                .....mss------.-.-PS..QAVKVVDVESA-K.FVNVVCGETVTFR.S....G.D.KSFSWKFEVL-..NHQAVDLMAVAPKG.F.TNKSLKVYITPN----lhe..
#=GC SS_cons                         .......H-CCEEE.E.-GG..G-SEEEE--TT--.EEEEETT-EEEEE.E....T.T.EEEEEEE--BS..S-EEEEHHHH-TTS.T.T-TT-EEEEEB-TT--X....
#=GC seq_cons                        .......t..aG...s.ssu..susRslslssss+.alNVssGETVpFp.s....G.s.KoFsWpFssh...spsshsLsplsPss.h.tscslpVYVu.ssha......
//
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