GenomeNet

Database: Pfam
Entry: DBD_Tnp_Hermes
LinkDB: DBD_Tnp_Hermes
Original site: DBD_Tnp_Hermes 
#=GF ID   DBD_Tnp_Hermes
#=GF AC   PF10683.10
#=GF DE   Hermes transposase DNA-binding domain  
#=GF PI   Hermes_DBD;
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   PDB:2bw3
#=GF GA   20.50 20.50;
#=GF TC   20.60 20.70;
#=GF NC   20.40 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   16041385
#=GF RT   Molecular architecture of a eukaryotic DNA transposase. 
#=GF RA   Hickman AB, Perez ZN, Zhou L, Musingarimi P, Ghirlando R,
#=GF RA   Hinshaw JE, Craig NL, Dyda F; 
#=GF RL   Nat Struct Mol Biol. 2005;12:715-721.
#=GF DR   INTERPRO; IPR018473;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain confers specific DNA-binding on Hermes transposase
#=GF CC   [1].
#=GF SQ   69
#=GS A0A388ME62_CHABU/76-134     AC A0A388ME62.1
#=GS A0A3P8R882_ASTCA/2-57       AC A0A3P8R882.1
#=GS A0A3B3H584_ORYLA/28-89      AC A0A3B3H584.1
#=GS A0A498NZ22_LABRO/340-399    AC A0A498NZ22.1
#=GS A0A3M7QIH6_BRAPC/77-119     AC A0A3M7QIH6.1
#=GS A0A3R7T198_PENVA/123-190    AC A0A3R7T198.1
#=GS A0A498NVN3_LABRO/106-170    AC A0A498NVN3.1
#=GS A0A3P9CWV5_9CICH/30-94      AC A0A3P9CWV5.1
#=GS A0A1D1V8W8_RAMVA/24-89      AC A0A1D1V8W8.1
#=GS A0A3B3BG73_ORYME/115-174    AC A0A3B3BG73.1
#=GS A0A443RUG6_9ACAR/82-146     AC A0A443RUG6.1
#=GS A0A2H5S0U0_RHIID/50-91      AC A0A2H5S0U0.1
#=GS A0A388LD20_CHABU/141-203    AC A0A388LD20.1
#=GS W5MVB0_LEPOC/2-47           AC W5MVB0.1
#=GS A0A1D1UZI3_RAMVA/87-153     AC A0A1D1UZI3.1
#=GS A0A2H5SAY7_RHIID/53-95      AC A0A2H5SAY7.1
#=GS H3ADM1_LATCH/80-136         AC H3ADM1.1
#=GS H2ZY74_LATCH/35-97          AC H2ZY74.1
#=GS A0A1X7U908_AMPQE/66-111     AC A0A1X7U908.1
#=GS A0A388M9Z9_CHABU/120-183    AC A0A388M9Z9.1
#=GS A0A388LT04_CHABU/1235-1298  AC A0A388LT04.1
#=GS A0A372QJ67_9GLOM/8-69       AC A0A372QJ67.1
#=GS A0A267G6Z1_9PLAT/107-148    AC A0A267G6Z1.1
#=GS A0A3B3QTA9_9TELE/68-124     AC A0A3B3QTA9.1
#=GS H3AVU8_LATCH/53-118         AC H3AVU8.1
#=GS A0A498LRZ9_LABRO/93-152     AC A0A498LRZ9.1
#=GS A0A498MFA3_LABRO/106-170    AC A0A498MFA3.1
#=GS A0A498LT40_LABRO/76-117     AC A0A498LT40.1
#=GS A0A498NMQ4_LABRO/101-160    AC A0A498NMQ4.1
#=GS A0A1I8PWK6_STOCA/702-770    AC A0A1I8PWK6.1
#=GS A0A388JVE7_CHABU/99-160     AC A0A388JVE7.1
#=GS A0A096M601_POEFO/57-99      AC A0A096M601.1
#=GS J9LQW3_ACYPI/1431-1490      AC J9LQW3.2
#=GS A0A1I8NKX5_MUSDO/506-572    AC A0A1I8NKX5.1
#=GS A0A388JV51_CHABU/120-183    AC A0A388JV51.1
#=GS A0A3B3T1Z0_9TELE/1-51       AC A0A3B3T1Z0.1
#=GS A0A1L8HVS6_XENLA/213-278    AC A0A1L8HVS6.1
#=GS A0A3B3T3J7_9TELE/88-149     AC A0A3B3T3J7.1
#=GS A0A3P9DLA7_9CICH/18-82      AC A0A3P9DLA7.1
#=GS A0A3P9CW01_9CICH/91-155     AC A0A3P9CW01.1
#=GS A0A3P9CNH9_9CICH/28-91      AC A0A3P9CNH9.1
#=GS A0A498L4Q9_LABRO/81-126     AC A0A498L4Q9.1
#=GS H3AQA6_LATCH/72-136         AC H3AQA6.1
#=GS A0A2H5T4Z3_RHIID/89-151     AC A0A2H5T4Z3.1
#=GS A0A3B5PRF4_XIPMA/86-129     AC A0A3B5PRF4.1
#=GS A0A3B4VA39_SERDU/98-142     AC A0A3B4VA39.1
#=GS W5N926_LEPOC/47-112         AC W5N926.1
#=GS A0A3P8Q0A3_ASTCA/18-82      AC A0A3P8Q0A3.1
#=GS X1XJW9_ACYPI/79-139         AC X1XJW9.1
#=GS A0A3P9BQP2_9CICH/10-74      AC A0A3P9BQP2.1
#=GS B4J9B1_DROGR/119-183        AC B4J9B1.1
#=GS H3A0S7_LATCH/68-128         AC H3A0S7.1
#=GS A0A3M7PBY3_BRAPC/145-196    AC A0A3M7PBY3.1
#=GS A0A015KDB4_RHIIW/85-125     AC A0A015KDB4.1
#=GS A0A3P8RB50_ASTCA/10-74      AC A0A3P8RB50.1
#=GS A0A498NCW1_LABRO/77-117     AC A0A498NCW1.1
#=GS H2ZW59_LATCH/78-142         AC H2ZW59.1
#=GS A0A498NZ22_LABRO/594-638    AC A0A498NZ22.1
#=GS A0A1I8PUM7_STOCA/753-816    AC A0A1I8PUM7.1
#=GS A0A484BUX7_DRONA/118-180    AC A0A484BUX7.1
#=GS A0A2H5R2W5_RHIID/85-124     AC A0A2H5R2W5.1
#=GS X1XJA9_ACYPI/115-162        AC X1XJA9.1
#=GS A0A0M3QT70_DROBS/43-105     AC A0A0M3QT70.1
#=GS A0A3P9DV23_9CICH/17-81      AC A0A3P9DV23.1
#=GS A0A2H5T1P1_RHIID/119-160    AC A0A2H5T1P1.1
#=GS A0A498LZM1_LABRO/57-97      AC A0A498LZM1.1
#=GS A0A1D1URG1_RAMVA/145-208    AC A0A1D1URG1.1
#=GS A0A3P9D1T5_9CICH/37-101     AC A0A3P9D1T5.1
#=GS X1XSV1_ACYPI/115-175        AC X1XSV1.1
A0A388ME62_CHABU/76-134                ...............wlk------------KNRMAK.KTAMWCC.KDLRPFNVVADEGFIDVVQEAYDMGAAV.GK..AMQMGKVIPVPNT..........................
A0A3P8R882_ASTCA/2-57                  .................f------------KKETRD.KCVQFVC.QDIRPYDTISGKGFTQLAQHLVDTAARI.G-..KFDVCEILPHPTT..........................
A0A3B3H584_ORYLA/28-89                 ...........rtaplra------------KQAITD.KCVDFCC.QNLRPFSVVSGEGFKSLAQELINVGSTF.G-..RVPVDSVLPHYTT..........................
A0A498NZ22_LABRO/340-399               ...........psgvksr---------------LTD.KIARMCS.QDLRPFAVVEGKGFTNVAQELLDIGAKY.GS..NVQVEDILPCART..........................
A0A3M7QIH6_BRAPC/77-119                .......ecesnkkvkpd---------------IDE.KLVEWII.DDLQPLSVVEGQKFIDLVN---------.--..-------------ild.......................
A0A3R7T198_PENVA/123-190               veeeqkdqfeleleksls-----------------K.VCSEFVI.RDMFPYQTLIGDGFKNLAQFLIDVGAVH.G-..KVDISPLFPEPK-k.........................
A0A498NVN3_LABRO/106-170               ..........pdhmkipl----------QVKSKFVD.YCVDFCC.TDLRPFDIVSGEGFTKVAQGLINIGARY.GS..-VDANGVLPHRQT..........................
A0A3P9CWV5_9CICH/30-94                 ..............tksl------LVPEKFKKETRD.KCVQFVC.QDIRPYDTISGKGFTQLAQHLVDTAARI.G-..KFDVCEILPHPTT..........................
A0A1D1V8W8_RAMVA/24-89                 ..............lpnv-------IPEAAKQKVSQ.ACARYCA.RDNRSFEEIKGRGFKDLINEVTDIAFKY.NS.gKFTAEELLPDQTT..........................
A0A3B3BG73_ORYME/115-174               ...........psgvksh---------------LAD.KIARMCS.QDLRPFAIVEGKGFIKVAQEMLDIGAKY.GS..NIQVEDILPSART..........................
A0A443RUG6_9ACAR/82-146                .............featk-------INSQEKAKLIE.AAVLFAA.KDLRPFSILDGDGFRAVAEQLIYIGNKY.G-..RIDLNDALPHSTT..........................
A0A2H5S0U0_RHIID/50-91                 .............ntqsq---------AEDHADILD.KLVNWVI.DDCQPFKVVDGVFFREFI----------.--..-------------asl.......................
A0A388LD20_CHABU/141-203               .vqpttsqkrqvaraamm------------------.----MCC.EDLRPFSIVEDAGFRCYSQVLLDIGISV.GR..GMKVDDLIPSRFT..........................
W5MVB0_LEPOC/2-47                      ..............efcc------------------.-------.WDIRPFHMIAGKGFIDLAQELINVGAIH.C-..RVPVECVLPNPTT..........................
A0A1D1UZI3_RAMVA/87-153                ..........emhklllv-----------AKQEVSK.VCARFCA.VDGRSFKEVSGKGFRALIDTVIDATMKY.GHagRPSVRDMIPDPTT..........................
A0A2H5SAY7_RHIID/53-95                 ........nekptqhgfr-----------------K.KLLQWVV.RDDQPFITIECQEFKNMVKYL-------.--..-------------wpsi......................
H3ADM1_LATCH/80-136                    ...........qsekkip---------VPKKKKKNN.KCVTLCC.KDIRPFETVSGKGFIELAQELVNVGATY.G-..-------------rvpan.....................
H2ZY74_LATCH/35-97                     ..........sekkillp-----------KKSEITD.KCVT-LL.QDIRPFETVSGKGFIELAQELINVGATY.G-..RVSASSVLPHPST..........................
A0A1X7U908_AMPQE/66-111                ..............kftk------SCSATRSKEIMR.RIAELVA.RDLRPISIVEGKGFKQLLNF--------.--..-------------iep.......................
A0A388M9Z9_CHABU/120-183               ............tvqpst----------SQKRQVAR.AVAMMCC.EDLGPFSIVEDPGFRRYSQVILDIGINV.GR..GMKVDDLIPSRFT..........................
A0A388LT04_CHABU/1235-1298             .........tvqpttsqk-------------RQVAR.AAAMMCC.EDLRPFSIVEDPGFRRYSQVILDIGISV.GR..GMKVDDLIPSRFT..........................
A0A372QJ67_9GLOM/8-69                  .......kepkqqylrng------------------.-LTDWLV.TDGRPFATIVGEGFKRFIK---------.--..-------------rvdpafivpcyrtlkadigagyqeal
A0A267G6Z1_9PLAT/107-148               .............sdshp------------RSVAIDrKILRFIV.LDSQPFSVVEGEGFRDLLK---------.--..-------------eacp......................
A0A3B3QTA9_9TELE/68-124                ......lrkyvetqlavk------------------.----SVS.RDIRSFETVSGVGFLELAQGLINIGARA.G-..KVDAQQILPNPTT..........................
H3AVU8_LATCH/53-118                    ...........qsekkip---------VPKKSEITD.KCVILCY.KDIRPFETVSGKGFIELVQELINVGATY.GR..VSAGSSVLPHPST..........................
A0A498LRZ9_LABRO/93-152                ...........lsgvksr---------------LTD.KIARMCS.QDLRPFAVVEGKGFTNVAQELLNIGAKY.GS..NVQVEDILPCART..........................
A0A498MFA3_LABRO/106-170               ..........pdhmkipl----------QVKSKFVD.YCVDFCC.TDLRPFDIVSGEGFTKVAQGLINIGARY.GS..-VDANGVLPHRQT..........................
A0A498LT40_LABRO/76-117                .......pltkstsdnlt-----------------N.TIAKWIA.KDCRPISTVEDSGFMDVLQ---------.--..-------------vasq......................
A0A498NMQ4_LABRO/101-160               ...........psgvksr---------------LTD.KIARMCS.QDLRPFAVVEGKGFTNVAQELLDIGAKY.GS..NVQVEDILPCART..........................
A0A1I8PWK6_STOCA/702-770               ................yt--KTLKKVNSEDKTQAFK.LFSNMLLyNDSLGLDATESAGFHQVIRFCLQLGAKY.GE..NVDVQDLMPP---kte.......................
A0A388JVE7_CHABU/99-160                ............eptaaq------------KKNLAK.AAALMYC.EDLRPFSIFSDAGFIKVTQVILDVGINI.GK..GMRAESLVPAPNT..........................
A0A096M601_POEFO/57-99                 ................pa-------VTGHRRQQITN.LLVNFIV.KDMRPLAAVHGEGFRDLLQFF-------.--..-------------ep........................
J9LQW3_ACYPI/1431-1490                 ............lpqsvm-------------KDCQE.KCVQFCS.QDIRPMDIVAGSGFKNLANYLISVGSKY.GE..-VSAENLLPHPTT..........................
A0A1I8NKX5_MUSDO/506-572               .............nnasi------EVSADFKQEAVR.IFTEWSI.ENCRSFKMVEDAGFKKLVEFLISLGATY.GK..QLDINSVLPNITT..........................
A0A388JV51_CHABU/120-183               ..........tvqpttsq------------KRQVAR.SAAMMCC.EDLRPFSIVEDAGFRRYSQVLLDIGISV.GR..GMKVDDLIPSRFT..........................
A0A3B3T1Z0_9TELE/1-51                  .................m-----------------E.SCAFFVA.SDICPYSIVAGPGFAQLIQTAIDIGASR.G-..KIDASELIPDQRT..........................
A0A1L8HVS6_XENLA/213-278               ..............rknf-----RASTHQDKEKITR.LAVKYVC.KDIRSFESINGDGFYELAQGLVDIGACV.G-..RVDVRTLLPDPTT..........................
A0A3B3T3J7_9TELE/88-149                ...............kkp--------SSADKVKFKE.SCAFFVA.SDIRPYNIVAGPGFAQLIQTAIDIGASR.G-..KIDASELIPDRRT..........................
A0A3P9DLA7_9CICH/18-82                 ..............tksl------LVPEKFKKETRD.KCVQFVC.QDIRPYDTISGKGFTQLAQHLVDTAARI.G-..KFDVCEILPHPTT..........................
A0A3P9CW01_9CICH/91-155                ..............tksl------LVPEKFKKETRD.KCVQFVC.QDIRPYDTISGKGFTQLAQHLVDTAARI.G-..KFDVCEILPHPTT..........................
A0A3P9CNH9_9CICH/28-91                 ..............ksfl-------VPEKFKKETRD.KCVQFVC.QDIRPYDTISGKGFTQLAQHLVDTAARI.G-..KFDVCEILPHPAT..........................
A0A498L4Q9_LABRO/81-126                ...............glr------------------.-------.QDLRPFAVVEGKGFTNVAQELLDIGAKY.GS..NVQVEDILPCART..........................
H3AQA6_LATCH/72-136                    ...........qsekkip---------VPKKSEITD.KCVTLCC.KDIQPFETVSGKGFIELAQELINVGATY.G-..RVSASSVLPHPST..........................
A0A2H5T4Z3_RHIID/89-151                .............kkeip---------TAAKEVTSK.KLINLVC.KDIRPFEIIVGQGFREFAQEMINIGATY.GN..-LPVDNLFPHPTT..........................
A0A3B5PRF4_XIPMA/86-129                ...............rpa-------VTGHRRQQITD.LLVNFIV.KDMRPLAAVHGEGFRDLLQFF-------.--..-------------ep........................
A0A3B4VA39_SERDU/98-142                ..............krpi--------TDHRKREITG.LLVNFIV.QDMRPLAAVSGNGFRDIIHFF-------.--..-------------elg.......................
W5N926_LEPOC/47-112                    ............lkpvts-------VPATVKSQLSD.KCVEFCF.WDIRPFHMVAEKGFIDLAQELINVGASH.G-..HVPSESVLPDPTT..........................
A0A3P8Q0A3_ASTCA/18-82                 ..............tksl------LVPEKFKKETRD.KCVQFVC.QDIRRYDTISGKGFTQLAQHLVDTAARI.G-..KFDVCEILPHPTT..........................
X1XJW9_ACYPI/79-139                    .............slkpr-----------VKDEAVE.KCVKYCS.LDLRPMLAIKGNGFLEIGKFFLDIGDKY.GV..-THINDIIPHPNT..........................
A0A3P9BQP2_9CICH/10-74                 ..............tksl------LVPEKFKKETRD.KCVQFVC.QDIRPYDTISGKGFTQLAQHLVDTAARI.G-..KFDVCEILPHPTT..........................
B4J9B1_DROGR/119-183                   ..........dalldded-----------TKGKLAQ.ALAEWAV.ENCRALDIFEDTGLRKLAALFIELGAYF.GT..QIKVDDLMPQT--aa........................
H3A0S7_LATCH/68-128                    .fvqsekkiplpkkseir------------------.-----QI.KDIQSFETVSGKRFIELVQELISVGATY.G-..RVSASSVLPHPST..........................
A0A3M7PBY3_BRAPC/145-196               ...........dsksssk----------IFKPNVDE.KLIEWII.DDLQPFSVVEGKKFIELVEM--------.--..-------------ldssykihcl................
A0A015KDB4_RHIIW/85-125                ........nekptqhgfr-----------------K.KLLQWVV.RDDQPFITIECQEFKNMVKYL-------.--..-------------wp........................
A0A3P8RB50_ASTCA/10-74                 ..............tksl------LVPEKFKKETRD.KCVQFVC.QDIRPYDTISGKGFTQLAQHLVDTAARI.G-..KFDVCEILPHPTT..........................
A0A498NCW1_LABRO/77-117                ........ltkstsdnlt-----------------N.TIAKWIA.KDCRPISIVEDSGFMDVLQ---------.--..-------------vasq......................
H2ZW59_LATCH/78-142                    ..............adat------KVSSSVKSELVN.SFVDMCC.TDLRPFGIVSGEGFKRVAQSLINIGARY.GS..-VNANMILPNRQT..........................
A0A498NZ22_LABRO/594-638               .......iqdgdsvivke------------------.-------.---------RGKGFTNVAQELLDIGAKY.GS..NVQVEDILPCART..........................
A0A1I8PUM7_STOCA/753-816               .......qakenqeikrk----------------FQ.PCINFII.EDCCPTSIVEGMGFRKFIEHCLQNGAQQiDN..DVEVQDFIPSLQT..........................
A0A484BUX7_DRONA/118-180               ...........vplsfei------------KDKLSD.AVVQWLV.KNGRSCNILQDSGLKDFVRILLTIGADF.GE..NVNMEDVIPNPAT..........................
A0A2H5R2W5_RHIID/85-124                .........ekptqhgfr-----------------K.KLLQWVV.RDDQPFITIECQEFKNMVKYL-------.--..-------------wp........................
X1XJA9_ACYPI/115-162                   ...........nlpqsvm-------------KDCQE.KCVQFCS.QDIRPMDIVAGSGFKNLANYLISVD---.--..-------------qgsn......................
A0A0M3QT70_DROBS/43-105                .............lsvdp----------QIKKKCTR.IMTESTV.KNGNFFSIIDDAGLKDLAEFFISVGANF.GE..NANVDTLLPQPDT..........................
A0A3P9DV23_9CICH/17-81                 ..............tksl------LVPEKFKKETRD.KCVQFVC.QDIRRYDTISGKGFTQLAQHLVDTAARI.G-..KFDVCEILPHPTT..........................
A0A2H5T1P1_RHIID/119-160               .............ntqsq---------AEDHADILD.KLVNWVI.DDCQPFKVVDGVLFREFI----------.--..-------------asl.......................
A0A498LZM1_LABRO/57-97                 ........ltkstsdnlt-----------------N.TIAKWIA.KDCRPISIVEDSGFIDVLQ---------.--..-------------vasq......................
A0A1D1URG1_RAMVA/145-208               .............klpra-----------AKQEMSR.VCARYCA.VDGRSFEEVAGTGFRALIDTVIDVTMKY.SHagKSTARDMLPDPTT..........................
A0A3P9D1T5_9CICH/37-101                ..............tksl------LVPEKFKKETRD.KCVQFVC.QDIRPYDTISGKGFTQLAQHLVDTAARI.G-..KFDVCEILPHPTT..........................
X1XSV1_ACYPI/115-175                   ...........nlpqsvm-------------KDCQE.KCVQFCS.QDIRPMDIVAGSGFKNLANYLISVGSKY.GE..-VSAENLLPHPTT..........................
#=GC seq_cons                          ..............pt.h............+pphtc.phspass.pDlRPashVpGpGFpplsQhllshuuph.G...thpsppllPp.pT..........................
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