GenomeNet

Database: Pfam
Entry: DEC-1_N
LinkDB: DEC-1_N
Original site: DEC-1_N 
#=GF ID   DEC-1_N
#=GF AC   PF04625.14
#=GF DE   DEC-1 protein, N-terminal region
#=GF AU   Kerrison ND;0000-0002-1471-953X
#=GF SE   DOMO:DM04594;
#=GF GA   29.20 29.20;
#=GF TC   29.50 51.60;
#=GF NC   29.10 29.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   1699826
#=GF RT   Multiple proteins are produced from the dec-1 eggshell gene in
#=GF RT   Drosophila by alternative RNA splicing and proteolytic cleavage
#=GF RT   events. 
#=GF RA   Waring GL, Hawley RJ, Schoenfeld T; 
#=GF RL   Dev Biol 1990;142:1-12.
#=GF DR   INTERPRO; IPR006719;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The defective chorion-1 gene (dec-1) in Drosophila encodes
#=GF CC   follicle cell proteins necessary for proper eggshell assembly.
#=GF CC   Multiple products of the dec-1 gene are formed by alternative
#=GF CC   RNA splicing and proteolytic processing [1].  Cleavage products
#=GF CC   include S80 (80 kDa) which is incorporated into the eggshell,
#=GF CC   and further proteolysis of S80 gives S60 (60 kDa).
#=GF SQ   39
#=GS A0A0R3P1K9_DROPS/83-479   AC A0A0R3P1K9.1
#=GS B3MRA8_DROAN/98-499       AC B3MRA8.2
#=GS A0A1W4VIK3_DROFC/78-500   AC A0A1W4VIK3.1
#=GS A0A0Q9XHG4_DROMO/194-537  AC A0A0Q9XHG4.1
#=GS A0A484AWD3_DRONA/187-531  AC A0A484AWD3.1
#=GS A0A3B0JDV3_DROGU/78-476   AC A0A3B0JDV3.1
#=GS A0A1B0A5N1_GLOPL/20-371   AC A0A1B0A5N1.1
#=GS B4MAG1_DROVI/180-513      AC B4MAG1.2
#=GS B4NCW6_DROWI/87-501       AC B4NCW6.2
#=GS B4IL40_DROSE/74-479       AC B4IL40.1
#=GS A0A1I8MEM2_MUSDO/74-529   AC A0A1I8MEM2.1
#=GS M9NEY9_DROME/74-480       AC M9NEY9.1
#=GS A0A484AWD3_DRONA/89-199   AC A0A484AWD3.1
#=GS DEC11_DROME/74-480        AC P18169.2
#=GS A0A0M5JAX0_DROBS/87-509   AC A0A0M5JAX0.1
#=GS A0A0Q9XHG4_DROMO/89-243   AC A0A0Q9XHG4.1
#=GS A0A0Q9X454_DROWI/87-501   AC A0A0Q9X454.1
#=GS DEC13_DROME/74-480        AC P18171.2
#=GS A0A0Q9WTZ3_DROWI/87-501   AC A0A0Q9WTZ3.1
#=GS B4R683_DROSI/74-454       AC B4R683.1
#=GS A0A1A9UNG7_GLOAU/161-368  AC A0A1A9UNG7.1
#=GS B4JK38_DROGR/204-546      AC B4JK38.1
#=GS B4L6A5_DROMO/191-536      AC B4L6A5.2
#=GS A0A1B0FAT4_GLOMM/151-371  AC A0A1B0FAT4.1
#=GS B5DMT1_DROPS/83-479       AC B5DMT1.2
#=GS DEC12_DROME/74-480        AC P18170.2
#=GS M9NG31_DROME/57-463       AC M9NG31.1
#=GS A0A3B0JCM6_DROGU/78-476   AC A0A3B0JCM6.1
#=GS B4L6A5_DROMO/89-240       AC B4L6A5.2
#=GS A0A0R3P5Q5_DROPS/83-479   AC A0A0R3P5Q5.1
#=GS A0A3B0J7S7_DROGU/78-476   AC A0A3B0J7S7.1
#=GS A0A1W4V6E9_DROFC/78-500   AC A0A1W4V6E9.1
#=GS A0A1A9WGV0_9MUSC/160-353  AC A0A1A9WGV0.1
#=GS B4JK38_DROGR/87-254       AC B4JK38.1
#=GS A0A1A9XQ57_GLOFF/158-373  AC A0A1A9XQ57.1
#=GS A0A1I8P693_STOCA/12-310   AC A0A1I8P693.1
#=GS B4MAG1_DROVI/83-187       AC B4MAG1.2
#=GS M9NEA7_DROME/57-463       AC M9NEA7.1
#=GS B4GVW6_DROPE/83-479       AC B4GVW6.1
A0A0R3P1K9_DROPS/83-479              ..............................................................................................................................................MLFPALGSLLRWGALFPAQSVLGAVPDSL....-QPTAAASKVVLVLADDPTA.KTRVTRQD-T.P-...-PA...P......NAFGQLLAQMPnpNFAq..gwMN.PANF........NPDSFNLGqiaPNVGQA..LTTMq.......................lPPMPqfGF.....E.NI.LGAA................PPPpP...AVVPPP...P.AE..PA.PPA....APA..A.DEPAAPVAAp................nPF..SFLTPNNFDVN....QLLGQ......A..QQALPPMPPMPAmpSNVDFFSNL.RQMWPGAPPASPGPApGSDGQASDISEVRVRPE....A..........-...-.......----------.A-----.DS...QE...N...A-LDD...KERVPLLWFRMPM.......NRQG...DE............G...E..A..KPL....E......DLRVEAKLRAFERQVIAELKMLQQIERVAKEMRSSA.....TSS.SGS..PYKVS......YPLSRTPVHKITRADIERALRDDYVRRLLHK..EAQRK....SRANH--.............AAFKRQTMPS.E..A...SMSKEDIVKIMAYAYRMATEQQSAA--qe..........
B3MRA8_DROAN/98-499                  ..............................................................................................................................................MMFPALGSLLRWGSVFPMGSLLGAVPDTL....LQPTGAASKVVLVLADDAAA.KTRVPRQDSP.PP...PPN...P......LDWAANVGQMI.tNMQ.....AN.P---........LLPPMPLD...ATLGAP..LQSL.........................LPLG..SL.....T.GI.LGQA................APA.P...AVSADP...P.PP..PA.PVP....DTP..A.PAPASP---..................PF..SAFDPANLGQSi..tSMLSQap..pnF..LSQMPAVPQIPQ..-----LQQF.AQFLPQIPGLSQAPV.G---QASDISEVRVRPE....I..........P...Y......vTGTPQMKIKT.ALEKEQ.DRrreQE...M...DQEQD...QERVPLLWFRLPV.......GHDR...N-............T...Q..G..KPI....E......DLRVEAKLKAFERQVITELKMLQQIERMAKEMRTSAat.gtAAQ.SSD..-YQLN......YPLNHTPVHKITRADIEQALRDDYVRRLVQK..EAQRR....GFINRKT.............GGYKRQAFAE.D..K...NLSKEEIVQIMAYAYRMANEQMAEAEK............
A0A1W4VIK3_DROFC/78-500              ..............................................................................................................................................LMFPALASLLRWGSLFPAHSILSAVPDNL....-QPTAAASKVVLVLADDPAT.KTRVTRQN--.-P...VTN...P......L------GQMM..NWP.....AV.PQDIlsq.anfpPLPPMDFG...PQVGQF..LAQL.........................PPMA..S-.....G.GF.LGAA................APV.P...TPVADP...P.PA..PAaPAP....APP..A.PAPPAPAAApdsplpalgqgiqpllgqAM..ALLNPTNIDPA....GLLGQ......-..--AVPNLSNLPA..PNLDFVAQMqRQFFPA--TVPAASA.GADAQASDISEVRVRPE....I..........P...Ys....peAQYAQLKIKS.ALERQQ.DR...QE...K...--QED...QERVPLLWFRLPT.......TTTT...ST............TdelE..D..KTL....E......DLRVEAKLRAFERQVIAELKMLQKIELMAKEMRSSA.....AQT.SPD.sPYRIN......YSLSRTPVHKITRSDIEHALRDDYVRRLVAK..EAQRKartsAHISRKA.............GGFKRQAKAE.D..P...TLTKEEIVKIMAYAYRMASEQMENEK-g...........
A0A0Q9XHG4_DROMO/194-537             ..................................................................................................................................prppagwlpdgf-----------------------------....--------------------.----------.--...---...-......-----SLGQMP..---.....PL.PDNFn.....lgQMPPMPPMpdaFNLGQM..APVMq.......................sFGLP..TL.....D.GL.LGQA................SAA.T...TTTPAP...PaAK..PA.DEP....AAP..A.PAPAGPTLGqa.............pppGF.gSFFDGSN----....NLLGS......A..LSGIPGAPTPD-..---SFMAGL.RQFLPG---------.-SSAQASDISEVRVKPEhhgsIny......raP...Qq....tqAQLAQLKIKS.ALQMEQ.EK...Q-...-...-----...--QVPLLWFRMPS.......KQEN...EE............E...QgdG..KTT....D......RAQIESKLEAFERQVIEELQQLQQIERLAREMRAHAq..geTAR.NGA..SYKLR......YPLSRTPVHKITRADIERALRDDYVRRLLSR..EMQRR....TYTKRQI.............MT-----GQQ.P..Q...SLSKEDIVKVMAYAYRMAAENAER---kakeqq......
A0A484AWD3_DRONA/187-531             ........................................................................................................................................aqmmpr-----------------------------....--------------------.----------.-P...PAGw.lP......D--GFSLGQMP..---.....PL.PDNFn.....lgQMPPMPDA...FNLGQM..APVMq.......................nFGLP..SL.....D.GL.LGQ-................APA.T...TTTTPA...P.PAatPA.DEP....AAP..A.PAPAGPTLGqa.............ppqGF.gAFFDGSN----....NLLGS......A..LSGIPGAPTPD-..---SFMAGL.RQFLPG-------SS.G---QASDISEVRVKPDshdsI..........N...YrapqqtqAQLAQLKIKS.ALQMEQ.EK...Q-...-...-----...--QVPLLWFRMPS.......KQET...EE............E...Q..GnaKTT....D......RAQIESKLEAFERQVIEELQQLQQIERLAREMRAHAq..geTAR.NGA..SYKLR......YPLSRTPVHKITRADIERALRDDYVRRLLNR..EMQRR....TYTKRQI.............MT-----GEQ.P..Q...TLSKEDIVKVMAYAYRMAAENAER---kakeqq......
A0A3B0JDV3_DROGU/78-476              ..............................................................................................................................................MLFPALGSLLRWGALFPAPTILGAVPDSL....-QPTAAASKVVLVLADDPTA.KTRVPRQD-A.PP...PTN...P......F--GQFLAQMP..NANfaqglMN.PANF........NPDNFNLGqmaPNVGQA..LTNMq.......................lPPMP..TMpqfgfE.NI.LG-A................APP.P...PPAALP...PaPA.ePA.PPA....DKP..A.DEPNAPVAAp................nPF..AFLNPSNFDMN....QMLGQ......A..QQ---SLPQMPS..-GVDFFSNL.RQMWPGAPPASPAP-.GSEGQASDISEIRVRPE....E..........-...-.......---------A.A-----.-Y...SQ...E...NNLDE...KERVPLLWFRMPM.......NRQG...DE............G...E..S..KPL....E......DLRVEAKLRAFERQVIAELKMLQQIERVAREMRSSAassrgSST.SGS..PFKIS......YPLSRTPVHKITRADIEQALRDDYVRRLLHK..EAQRK....SRANH--.............AAFKRQTMPA.D..A...SMSKEDIVKIMAYAYRMATEQQTAEK-nk..........
A0A1B0A5N1_GLOPL/20-371              qesanhddvsvqrfarqnpdffqdlmaqfqrmndqmaqqwvpalsqisdgfqqgapllqqmpllgqslaqsilsssdsllgafsrsnddeddeetqqtpasqkdkeqskgqqrpkqpwetmlgtpllglqsfiqnppppfny-----------------------------....--------------------.----------.--...---...-......-----------..---.....--.----........--------...------..----.........................----..--.....-.--.----................---.-...------...-.--..--.---....---..-.---------..................--..-----------....-----......-..------------..---------.NPFIPG---WSNQM-.-QQASASDISEVRVKPD....I..........-...V.......DPTHRLSRKT.SRDRNA.GN..tQN...Y...AFSNAeilKKNMPLLWLHLTK.......PKSV...N-............-...-..S..KNP....K......DKETQAKLSTFEDELVLELQYLQKVVKLANQVKRLK.....PYS.TNA..GNSKA......LPLSEISVYKMTMGDIEEALKDEDVLTILHT..LNQYH....HTIPN--.............---KRQISSK.DllQ...KLSAEDLMKIIGYNSRMSP--------klennwmkge..
B4MAG1_DROVI/180-513                 ....................................................................................................................................vpagwlpdgf-----------------------------....--------------------.----------.--...---...-......-----TLGQMP..---.....PL.PDNFn.....lgQMPPLPDG...FNLGQM..APVMp.......................nFGLR..PL.....E.SL.LGQA................PVA.P...ATTAAP...P.AA..KP.ASE....SEP..A.PAPAVGQAP..................PAagAGF-GALFDGS...nNLLGQ......A..FSGMPAAPTPDA..----FMAGL.RQFWPGAA---PPTG.DRSAQASDISEVRVKPD....NhnqdtigyraPqqaH.......AQLAQMKIKS.ALQLEQ.EK...--...-...-----...-QRVPLLWFRMPS.......SETQ...Q-............-...-..S..KST....E......RAQIESKLQAFEQQVIAELQQLQQIERMAREMRANA.....QGE.TPA..-YKLR......YPLSRTPVHKITRADIERALRDDYVRRLLQK..EAQRK....T------.............-NFKRQTQQQpE..Q...LLTKEDIVKVMAYAYRMANENAER---kak.........
B4NCW6_DROWI/87-501                  ..............................................................................................................................................MLFPALGSLLRWGSLFPAHTILGAVPDSLpnvsTQPQAAASKVVLVLADDAQA.KSRVARQNAG.TP...ALN..gP......DMFTSLLGQMA..---.....--.PQNLg......qMMSPESLGqfvPQVGQA..LQNFql....................pqgLPFQ..GL.....D.NF.LG--................APL.P...VLGAPP...PtPA..PA.PTPkaasDDP..A.PAPATPPAG..................SF.aAFFNPSNFDAP....GLLGQ......M..QAQLPPLPAAPA..GTPDFMAGL.RQFWPG-AAASGGAA.GSDAQASDISEVRVKPG....-..........-...-.......EQLAQLKIKT.P-----.--...QD...L...DQDKE...QENVPLLWFRLPI.......SQEE...SS............E...K..D..KTT....E......DLRIKNKLQAFERQVISELKLLQQIERLAKEMRAQA.....SAQ.GAS..PYKLN......YPLSRTPVHKITRADIERALRDDYVRRLLHK..EAQRK....SWIGQKAkyirdeaagketgAALKRQT---.-..-...NLSKDEIIKMMAYAYRMANEQQQQAE-ek..........
B4IL40_DROSE/74-479                  ..............................................................................................................................................MMFPALGSLLRWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-P...PPN...P......L------GQLM..NWP.....AL.PQDF........QLPSMDLG...PQVGSF..LTQL.........................PAMP..SM.....P.GL.LGAA................APV.P...APAPAPaaaP.PA..PA.PAV....DPP.aA.PAPDAAQPAilgq.........aalqnAF..TFLNPSNFDAS....SLLGQ......-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAPA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKS.ALQMEQ.ER...QQ...Q...VQVKD...QEQVPLLWFRMPT.......TQNL...DT............T...E..E..KTL....E......DLRVEAKLRAFERQVIAELKMLQKIELMAKQMRSSA.....AAQ.NGD.tPYRIS......YPLSRTPIHKITRADIEQALRDDYVRRLVNK..EAQRKarnsGNNTQKA.............NALKRQAKSQ.D..Q...TLSKEDIVQIMAYAYRMANEQMESEK-g...........
A0A1I8MEM2_MUSDO/74-529              ................................................................................................................................lgqtfgrtpsaaaq---------------------------SL....-DTQPEASKVVLVLANDTPV.TSALPQPDEE.TLkrlVRN...P......DFFQELLTRME..SIN.....EQlTTHV........PAITRTFG...QGVNEA..LSQApilgqaqqsgaidyarlgeafgetiLPQN..ML.....A.GM.-GEAlnmtssannatdsetlN--.-...------...E.TE..PL.GVD....LSP..E.PAPESPPPS..................QE..-PQAPAQAPQGspfgSLLGEnplfrsF..QQFVP--PQLPP..ASADG---I.PFSFPW---LQ--QA.GSQGAASDISEVRVKPD....T..........Pn.pYr....isPKEADMTQKI.N--EMK.LR...AA...M...KDALT...KKTIPILWFRIPD.......KKED...SArrp......vasN...R..E..SAV...dE......DLKMQLKLEAFEKQLIDELHQLQEVVKLANAMKKAQle.srE--.-KT..RSEINeanlkpLTLNETPIYKITLADIERTLKDEYVQKLLQM..AAQSR...kKEKEQKNkalfnkypsesvnNPNKRQTSAG.D..TglaTLDRDDLMKMMLYAYRTAALQ------gdnts.......
M9NEY9_DROME/74-480                  ..............................................................................................................................................MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-P...PPN...P......L------GQLM..NWP.....AL.PQDF........QLPSMDLG...PQVGSF..LAQL.........................PAMP..TV.....P.GL.LGAAap............vpAPA.P...APAAAP...P.PA..PA.PAA....DPP.aA.PVPDAPQPAilgq.........aalqnAF..TFFNPANFDAS....SLLGQ......-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKS.ALEMEQ.ER...QQ...Q...AQVKD...QEQVPLLWFRMPT.......TQNQ...DA............T...E..E..KTL....E......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA.....AAQ.NGD.sPYRIS......YPLSRTPIHKITRADIEQALRDDYVRRLVNK..EAQRRarnsGINTQKA.............NALKRQAKSQ.D..Q...TLSKEDIVQIMAYAYRMANEQMESEK-g...........
A0A484AWD3_DRONA/89-199              .............................................................................................................................................f-MFPALSSLLRWGSLFPAQTLLGAMPDNL....---QASPSKVVLVLADDANAhKSRVTRQDAA.PA...APA...P......PAPPAAPGAAM..-LQ.....QM.QQML.......gQMPPPNLA...QIVPPN..LAQM.........................MP--..--.....-.--.----................---.-...------...-.--..--.---....---..-.---------..................--..-----------....-----......-..------------..---------.---------------.-----------------....-..........-...-.......----------.------.--...--...-...-----...-------------.......----...--............-...-..-..---....-......------------------------------------.....---.---..-----......-------------------------------..-----....-------.............----------.-..-...---------------------------rppagwlp....
DEC11_DROME/74-480                   ..............................................................................................................................................MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-P...PPN...P......L------GQLM..NWP.....AL.PQDF........QLPSMDLG...PQVGSF..LAQL.........................PAMP..TV.....P.GL.LGAAap............vpAPA.P...APAAAP...P.PA..PA.PAA....DPP.aA.PVPDAPQPAilgq.........aalqnAF..TFFNPANFDAS....SLLGQ......-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKS.ALEMEQ.ER...QQ...Q...AQVKD...QEQVPLLWFRMPT.......TQNQ...DA............T...E..E..KTL....E......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA.....AAQ.NGD.sPYRIS......YPLSRTPIHKITRADIEQALRDDYVRRLVNK..EAQRRarnsGINTQKA.............NALKRQAKSQ.D..Q...TLSKEDIVQIMAYAYRMANEQMESEK-g...........
A0A0M5JAX0_DROBS/87-509              .............................................................................................................................................f-LFPALSSLLRWGSLFPAPSLLGAVPDSL....-QP--AASKVVLVLADDANAhKSRVTRQDTP.NPqapAAA...PpgadilQQFFTQVGQAP..---.....--.PPNFnqfmeqgqQMIQNMGQ...PQVGSAnpLNGLf......................gqTPFN..LF.....G.GL.VGAA................AP-.P...AAEPAA...P.PA..PA.TTA....ATPtaK.SADETPATQ..................PF..NFFNAPMFDGN...sNLLGM......A..M--PQGLPQAPS..-LDAFMSGL.RQLTPN---AQ----.-PSAQASDISEVRVRPE....-..........-...T.......DMQAQHKIQS.ALEKQQ.QQ...QQ...Q...---QQ...KQRVPLLWFRMRQ.......SADNnenNE............E...S..D..KPT....D......QLKIESKLQAFERQVIAELRMLQHIERMAKEMRATAaqrpeSNQrNGA.pAYKVR......YPLSRTPVHKITRSDIERALRDEDVRRLIHA..EAKRM....SATRESQlplh.....krqaASTMPSTSAQ.S..Q..lTLSKEDIVSMLAYAYRMANESS-----atgrs.......
A0A0Q9XHG4_DROMO/89-243              .............................................................................................................................................f-MFPALSSLLRWGSLFPAQTLLGAVPDNL....---QASPSKVVLVLADDANGhKSRVTRQDAA.PA...APAppaP......APPGALNGAAM..-LQ.....QM.QQML.......gQMPPPNLA...QMVPPN..LAQMm......................prPPAG..WL.....PdGFsLGQM................PPL.PdnfNLGQMP...P.MP..PM.PDA....---..-.---------..................--..-----------....-----......-..------------..---------.---------------.-----------------....-..........-...-.......----------.------.--...--...-...-----...-------------.......----...--............-...-..-..---....-......------------------------------------.....---.---..-----......-------------------------------..-----....-------.............----------.-..-...---------------------------fnlgqmapvmqs
A0A0Q9X454_DROWI/87-501              ..............................................................................................................................................MLFPALGSLLRWGSLFPAHTILGAVPDSLpnvsTQPQAAASKVVLVLADDAQA.KSRVARQNAG.TP...ALN..gP......DMFTSLLGQMA..---.....--.PQNLg......qMMSPESLGqfvPQVGQA..LQNFql....................pqgLPFQ..GL.....D.NF.LG--................APL.P...VLGAPP...PtPA..PA.PTPkaasDDP..A.PAPATPPAG..................SF.aAFFNPSNFDAP....GLLGQ......M..QAQLPPLPAAPA..GTPDFMAGL.RQFWPG-AAASGGAA.GSDAQASDISEVRVKPG....-..........-...-.......EQLAQLKIKT.P-----.--...QD...L...DQDKE...QENVPLLWFRLPI.......SQEE...SS............E...K..D..KTT....E......DLRIKNKLQAFERQVISELKLLQQIERLAKEMRAQA.....SAQ.GAS..PYKLN......YPLSRTPVHKITRADIERALRDDYVRRLLHK..EAQRK....SWIGQKAkyirdeaagketgAALKRQT---.-..-...NLSKDEIIKMMAYAYRMANEQQQQAE-ek..........
DEC13_DROME/74-480                   ..............................................................................................................................................MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-P...PPN...P......L------GQLM..NWP.....AL.PQDF........QLPSMDLG...PQVGSF..LAQL.........................PAMP..TV.....P.GL.LGAAap............vpAPA.P...APAAAP...P.PA..PA.PAA....DPP.aA.PVPDAPQPAilgq.........aalqnAF..TFFNPANFDAS....SLLGQ......-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKS.ALEMEQ.ER...QQ...Q...AQVKD...QEQVPLLWFRMPT.......TQNQ...DA............T...E..E..KTL....E......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA.....AAQ.NGD.sPYRIS......YPLSRTPIHKITRADIEQALRDDYVRRLVNK..EAQRRarnsGINTQKA.............NALKRQAKSQ.D..Q...TLSKEDIVQIMAYAYRMANEQMESEK-g...........
A0A0Q9WTZ3_DROWI/87-501              ..............................................................................................................................................MLFPALGSLLRWGSLFPAHTILGAVPDSLpnvsTQPQAAASKVVLVLADDAQA.KSRVARQNAG.TP...ALN..gP......DMFTSLLGQMA..---.....--.PQNLg......qMMSPESLGqfvPQVGQA..LQNFql....................pqgLPFQ..GL.....D.NF.LG--................APL.P...VLGAPP...PtPA..PA.PTPkaasDDP..A.PAPATPPAG..................SF.aAFFNPSNFDAP....GLLGQ......M..QAQLPPLPAAPA..GTPDFMAGL.RQFWPG-AAASGGAA.GSDAQASDISEVRVKPG....-..........-...-.......EQLAQLKIKT.P-----.--...QD...L...DQDKE...QENVPLLWFRLPI.......SQEE...SS............E...K..D..KTT....E......DLRIKNKLQAFERQVISELKLLQQIERLAKEMRAQA.....SAQ.GAS..PYKLN......YPLSRTPVHKITRADIERALRDDYVRRLLHK..EAQRK....SWIGQKAkyirdeaagketgAALKRQT---.-..-...NLSKDEIIKMMAYAYRMANEQQQQAE-ek..........
B4R683_DROSI/74-454                  ..............................................................................................................................................MMFPALGSLLRWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-P...PPN...P......L------GQLM..NWP.....AL.PQDF........QLPSMDLG...PQVGSF..LSQLp......................amPAMP..SM.....P.GL.LGAA................APV.P...APAPAPaaaP.PA..PA.PAA....DPP..ApPAPDAAQPAilgq.........aalqnAF..TFLNPSNFDAS....SLLGQ......-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAPA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKS.ALQMEQ.ER...QQ...Q...VQVKD...QEQVPLLWFRMPT.......TQNH...DA............T...E..E..KTL....E......DLRVEAKLRAFERQVIAELKMLQKIELMAKQMRSSA.....AAQ.NGD.tPYRIS......YPLSRTPIHKITRADIEQALRDDYVRRLVNK..EAQRKarnsGVNTQKA.............NALKRPGF--.-..-...---------------------------sfc.........
A0A1A9UNG7_GLOAU/161-368             ...............................................................................................................................fnynpfipvwpnqmq-----------------------------....--------------------.----------.--...---...-......-----------..---.....--.----........--------...------..----.........................----..--.....-.--.----................---.-...------...-.--..--.---....---..-.---------..................--..-----------....-----......-..------------..---------.---------------.--QASASDISEVRVKPD....I..........V...G.......PAYRLSRQTT.RANDAG.DM...QNypfS...NAEIL...KKNMPLLWLHLTK.......SKSA...NS............K...N..P..KDK....E......TL---AKLSTFEDELVLELEYLQKVVKLANQMKRLK....pYGT.NAD..-NSKA......LPLSEISVYKMTMGDIEEALKDEDVLTTLHT..LNQYR....YTIPN--.............---KRQISSN.DllQ...KLSAQDLMKIIGYNSRMS---------pkvesn......
B4JK38_DROGR/204-546                 ............................................................................................................................................pp-----------------------------....--------------------.----------.IP...AIP...P......IPNTFNLGQMA.pNLA.....NL.G---........QMPNLGQM...PNLGQLpnLGQM.........................ANLG..Q-.....M.AF.LGQA................APV.P...EASTTA...A.-P..PT.PKS....DDP.sP.PAPSVAQAA..................PLfgGLFDGGN----....NFLGP......-..-------P----..--DALMAGL.RQFIPGGVVAPPAPA.GSSAQASDISEVRVKPAgepiM..........S...YrspqqtdAQLSQFRINT.ALRM--.--...QQ...R...EQEQD...KQQMPLVWLRMPTedtdttkTQTK...TE............T...G..D..KTD....EphkprdRMEIEARLHAFQRQVIAELQQLQHIERLAREMRASA.....QGA.SVT.pTFKLR......YPLSRTPVHKITRADIEGALRDDYVRRLLHK..EALRK....T------.............-NYKRQT-ME.Q..Q...SMSKEDILKVMAYAYRVASESAEK---kane........
B4L6A5_DROMO/191-536                 ...............................................................................................................................qmmprppagwlpdgf-----------------------------....--------------------.----------.--...---...-......-----SLGQMP..---.....PL.PDNFn.....lgQMPPMPPMpdaFNLGQM..APVMq.......................sFGLP..TL.....D.GL.LGQA................SAA.T...TTTPAP...PaAK..PA.DEP....AAP..A.PAPAGPTLGqa.............pppGF.gSFFDGSN----....NLLGS......A..LSGIPGAPTPD-..---SFMAGL.RQFLPG---------.-SSAQASDISEVRVKPEhhgsIny......raP...Qq....tqAQLAQLKIKS.ALQMEQ.EK...Q-...-...-----...--QVPLLWFRMPS.......KQEN...EE............E...QgdG..KTT....D......RAQIESKLEAFERQVIEELQQLQQIERLAREMRAHAq..geTAR.NGA..SYKLR......YPLSRTPVHKITRADIERALRDDYVRRLLSR..EMQRR....TYTKRQI.............MT-----GQQ.P..Q...SLSKEDIVKVMAYAYRMAAENAER---kakeq.......
A0A1B0FAT4_GLOMM/151-371             ......................................................................................................................qsfmqnppppfnynpfitgwsnqm-----------------------------....--------------------.----------.--...---...-......-----------..---.....--.----........--------...------..----.........................----..--.....-.--.----................---.-...------...-.--..--.---....---..-.---------..................--..-----------....-----......-..------------..---------.---------------.-QQASASDISEVRVKPD....I..........-...V.......DPTHRLSRKT.TRDNNAgDT...QN...YpfsNAEIL...RKNMPLLWLHVTK.......SKSV...--............-...N..S..KNP....K......DKQTQAKLSTFKDELVLELQNLQKVVKLANQVKRLKp...ySTN.AG-..-NSKA......LSLSEISVYKMTMGDIEEALKDEDVLTILHT..LNQYR....-----RT.............TPNKRQISSN.DllQ...KLSAEDLMKIIGYNSRMSP--------klennwmk....
B5DMT1_DROPS/83-479                  ..............................................................................................................................................MLFPALGSLLRWGALFPAQSVLGAVPDSL....-QPTAAASKVVLVLADDPTA.KTRVTRQD-T.P-...-PA...P......NAFGQLLAQMPnpNFAq..gwMN.PANF........NPDSFNLGqiaPNVGQA..LTTMq.......................lPPMPqfGF.....E.NI.LGAA................PPPpP...AVVPPP...P.AE..PA.PPA....APA..A.DEPAAPVAAp................nPF..SFLTPNNFDVN....QLLGQ......A..QQALPPMPPMPAmpSNVDFFSNL.RQMWPGAPPASPGPApGSDGQASDISEVRVRPE....A..........-...-.......----------.A-----.DS...QE...N...A-LDD...KERVPLLWFRMPM.......NRQG...DE............G...E..A..KPL....E......DLRVEAKLRAFERQVIAELKMLQQIERVAKEMRSSA.....TSS.SGS..PYKVS......YPLSRTPVHKITRADIERALRDDYVRRLLHK..EAQRK....SRANH--.............AAFKRQTMPS.E..A...SMSKEDIVKIMAYAYRMATEQQSAA--qe..........
DEC12_DROME/74-480                   ..............................................................................................................................................MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-P...PPN...P......L------GQLM..NWP.....AL.PQDF........QLPSMDLG...PQVGSF..LAQL.........................PAMP..TV.....P.GL.LGAAap............vpAPA.P...APAAAP...P.PA..PA.PAA....DPP.aA.PVPDAPQPAilgq.........aalqnAF..TFFNPANFDAS....SLLGQ......-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKS.ALEMEQ.ER...QQ...Q...AQVKD...QEQVPLLWFRMPT.......TQNQ...DA............T...E..E..KTL....E......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA.....AAQ.NGD.sPYRIS......YPLSRTPIHKITRADIEQALRDDYVRRLVNK..EAQRRarnsGINTQKA.............NALKRQAKSQ.D..Q...TLSKEDIVQIMAYAYRMANEQMESEK-g...........
M9NG31_DROME/57-463                  ..............................................................................................................................................MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-P...PPN...P......L------GQLM..NWP.....AL.PQDF........QLPSMDLG...PQVGSF..LAQL.........................PAMP..TV.....P.GL.LGAAap............vpAPA.P...APAAAP...P.PA..PA.PAA....DPP.aA.PVPDAPQPAilgq.........aalqnAF..TFFNPANFDAS....SLLGQ......-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKS.ALEMEQ.ER...QQ...Q...AQVKD...QEQVPLLWFRMPT.......TQNQ...DA............T...E..E..KTL....E......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA.....AAQ.NGD.sPYRIS......YPLSRTPIHKITRADIEQALRDDYVRRLVNK..EAQRRarnsGINTQKA.............NALKRQAKSQ.D..Q...TLSKEDIVQIMAYAYRMANEQMESEK-g...........
A0A3B0JCM6_DROGU/78-476              ..............................................................................................................................................MLFPALGSLLRWGALFPAPTILGAVPDSL....-QPTAAASKVVLVLADDPTA.KTRVPRQD-A.PP...PTN...P......F--GQFLAQMP..NANfaqglMN.PANF........NPDNFNLGqmaPNVGQA..LTNMq.......................lPPMP..TMpqfgfE.NI.LG-A................APP.P...PPAALP...PaPA.ePA.PPA....DKP..A.DEPNAPVAAp................nPF..AFLNPSNFDMN....QMLGQ......A..QQ---SLPQMPS..-GVDFFSNL.RQMWPGAPPASPAP-.GSEGQASDISEIRVRPE....E..........-...-.......---------A.A-----.-Y...SQ...E...NNLDE...KERVPLLWFRMPM.......NRQG...DE............G...E..S..KPL....E......DLRVEAKLRAFERQVIAELKMLQQIERVAREMRSSAassrgSST.SGS..PFKIS......YPLSRTPVHKITRADIEQALRDDYVRRLLHK..EAQRK....SRANH--.............AAFKRQTMPA.D..A...SMSKEDIVKIMAYAYRMATEQQTAEK-nk..........
B4L6A5_DROMO/89-240                  .............................................................................................................................................f-MFPALSSLLRWGSLFPAQTLLGAVPDNL....---QASPSKVVLVLADDANGhKSRVTRQDAA.PA...APAppaP......APPGALNGAAM..-LQ.....QM.QQML.......gQMPPPNLA...QMVPPN..LAQMm......................prPPAG..WL.....PdGFsLGQM................PPL.PdnfNLGQMP...P.MP..PM.PDA....---..-.---------..................--..-----------....-----......-..------------..---------.---------------.-----------------....-..........-...-.......----------.------.--...--...-...-----...-------------.......----...--............-...-..-..---....-......------------------------------------.....---.---..-----......-------------------------------..-----....-------.............----------.-..-...---------------------------fnlgqmapv...
A0A0R3P5Q5_DROPS/83-479              ..............................................................................................................................................MLFPALGSLLRWGALFPAQSVLGAVPDSL....-QPTAAASKVVLVLADDPTA.KTRVTRQD-T.P-...-PA...P......NAFGQLLAQMPnpNFAq..gwMN.PANF........NPDSFNLGqiaPNVGQA..LTTMq.......................lPPMPqfGF.....E.NI.LGAA................PPPpP...AVVPPP...P.AE..PA.PPA....APA..A.DEPAAPVAAp................nPF..SFLTPNNFDVN....QLLGQ......A..QQALPPMPPMPAmpSNVDFFSNL.RQMWPGAPPASPGPApGSDGQASDISEVRVRPE....A..........-...-.......----------.A-----.DS...QE...N...A-LDD...KERVPLLWFRMPM.......NRQG...DE............G...E..A..KPL....E......DLRVEAKLRAFERQVIAELKMLQQIERVAKEMRSSA.....TSS.SGS..PYKVS......YPLSRTPVHKITRADIERALRDDYVRRLLHK..EAQRK....SRANH--.............AAFKRQTMPS.E..A...SMSKEDIVKIMAYAYRMATEQQSAA--qe..........
A0A3B0J7S7_DROGU/78-476              ..............................................................................................................................................MLFPALGSLLRWGALFPAPTILGAVPDSL....-QPTAAASKVVLVLADDPTA.KTRVPRQD-A.PP...PTN...P......F--GQFLAQMP..NANfaqglMN.PANF........NPDNFNLGqmaPNVGQA..LTNMq.......................lPPMP..TMpqfgfE.NI.LG-A................APP.P...PPAALP...PaPA.ePA.PPA....DKP..A.DEPNAPVAAp................nPF..AFLNPSNFDMN....QMLGQ......A..QQ---SLPQMPS..-GVDFFSNL.RQMWPGAPPASPAP-.GSEGQASDISEIRVRPE....E..........-...-.......---------A.A-----.-Y...SQ...E...NNLDE...KERVPLLWFRMPM.......NRQG...DE............G...E..S..KPL....E......DLRVEAKLRAFERQVIAELKMLQQIERVAREMRSSAassrgSST.SGS..PFKIS......YPLSRTPVHKITRADIEQALRDDYVRRLLHK..EAQRK....SRANH--.............AAFKRQTMPA.D..A...SMSKEDIVKIMAYAYRMATEQQTAEK-nk..........
A0A1W4V6E9_DROFC/78-500              ..............................................................................................................................................LMFPALASLLRWGSLFPAHSILSAVPDNL....-QPTAAASKVVLVLADDPAT.KTRVTRQN--.-P...VTN...P......L------GQMM..NWP.....AV.PQDIlsq.anfpPLPPMDFG...PQVGQF..LAQL.........................PPMA..S-.....G.GF.LGAA................APV.P...TPVADP...P.PA..PAaPAP....APP..A.PAPPAPAAApdsplpalgqgiqpllgqAM..ALLNPTNIDPA....GLLGQ......-..--AVPNLSNLPA..PNLDFVAQMqRQFFPA--TVPAASA.GADAQASDISEVRVRPE....I..........P...Ys....peAQYAQLKIKS.ALERQQ.DR...QE...K...--QED...QERVPLLWFRLPT.......TTTT...ST............TdelE..D..KTL....E......DLRVEAKLRAFERQVIAELKMLQKIELMAKEMRSSA.....AQT.SPD.sPYRIN......YSLSRTPVHKITRSDIEHALRDDYVRRLVAK..EAQRKartsAHISRKA.............GGFKRQAKAE.D..P...TLTKEEIVKIMAYAYRMASEQMENEK-g...........
A0A1A9WGV0_9MUSC/160-353             ................................................................................................................................nynpfvsswsdemq-----------------------------....--------------------.----------.--...---...-......-----------..---.....--.----........--------...------..----.........................----..--.....-.--.----................---.-...------...-.--..--.---....---..-.---------..................--..-----------....-----......-..------------..---------.---------------.--QASASDISEVRVKPE....-..........T...V.......NTIYKLYPKT.T---QT.NK...MS...N...MQNYK...F------------.......SNEK...TL............K...K..N..LPL....L......HKETQAKLSTPEDELIVELKWLQSIAKLANQMKSLK.....PYD.TKS..DSLNT......LRLGEISVYKVTIEDIEKALKDEDVLAILHT..FNQHR....HTIP---.............--SKRQVSSN.DflR...KFSAEDLMKIIGHPSRMSSD-------eklvdnn.....
B4JK38_DROGR/87-254                  .............................................................................................................................................s-MFPALSSLLRWGSLFPAQSVLGAVPDTL....-QP--AASKVVLVLADEANGhKSRRTRQDTP.AP...TPA..aP......----AAPGAML..---.....--.-QQ-........FLSQMPSP...ANLQQM..MPQL.........................PTGW..LP.....D.NFqLGQM................PPM.P...DLGQMP...P.IP..PI.PAI....---..P.PIPNTFNLG..................QM..-APNLANLGQM....PNLGQ......MpnLGQLPNLGQMA-..---------.---------------.-----------------....-..........-...-.......----------.------.--...--...-...-----...-------------.......----...--............-...-..-..---....-......------------------------------------.....---.---..-----......-------------------------------..-----....-------.............----------.-..-...---------------------------nlgq........
A0A1A9XQ57_GLOFF/158-373             ............................................................................................................................pppfnynpfipawpnqrq-----------------------------....--------------------.----------.--...---...-......-----------..---.....--.----........--------...------..----.........................----..--.....-.--.----................---.-...------...-.--..--.---....---..-.---------..................--..-----------....-----......-..------------..---------.---------------.--QASASEMSEVRVKPD....I..........V...D.......-PTYRFSRKTtRANKPG.DM...QN...YpfsNAEIL...KKNMPLLWLHLTK.......SKSV...NS............N...K..P..K--....-......DKETQAKLSTFEDELVLELKYLQKVVKLANQAKRLK....pYGT.NAS..-ISKA......LSLSDISVYKITMGDIEKALKDEDVLTILHT..LNQYR....HTIPN--.............---KRQISSN.DllQ...KLSAEDLMKIISHNSRMSP--------kvennwmkge..
A0A1I8P693_STOCA/12-310              ...........................................................................................aprrsndqvpglpfdssalldsplfrslqqfvpstfspasapssersgags-----------------------------....--------------------.----------.--...---...-......-----------..---.....--.----........--------...------..----.........................----..--.....-.--.----................---.-...------...-.--..--.---....---..-.---------..................--..-----------....-----......-..------------..----FMFNP.SQYLSW-----LQNS.NPESAASDISEVRVKPD....M..........P...F.......RISPKGASQK.MSEM-K.LR...AA...M...REALT...KKTIPILWFRLAE.......KNAR...DSssspfsttsdetK...S..D..KPLavtdE......DLKMQMKLASFERQLIEELQQLQEVVKLANALKKAQl..eaKGR.KAEdhPSLKP......LTLSSTPLYKITLADIEKTLKDEYVQKLLQMasNAKKR...dQMLRNKSangky..nsdflgNPNKRQT-PG.A..S...SINKDELLQMMAYAYRMAAS-------ngqdms......
B4MAG1_DROVI/83-187                  ..............................................................................................................................................LMFPALSSLLRWGSLFPAQSLLGAMPDTL....-QP--AASKVVLVLADEANGhKSRVTRQDATaQP...APA...A......AAPTAMNGPAM..-LQ.....QM.QQML.......gQMPPPNLG...QMLPQ-..----.........................----..--.....-.--.----................---.-...------...-.--..--.---....---..-.---------..................--..-----------....-----......-..------------..---------.---------------.-----------------....-..........-...-.......----------.------.--...--...-...-----...-------------.......----...--............-...-..-..---....-......------------------------------------.....---.---..-----......-------------------------------..-----....-------.............----------.-..-...---------------------------vpagwlpd....
M9NEA7_DROME/57-463                  ..............................................................................................................................................MMFPALGSLLKWGSLFPAYSILGAIPDNL....-QPTAAASKVVLVLADDATA.KTRVARQN--.-P...PPN...P......L------GQLM..NWP.....AL.PQDF........QLPSMDLG...PQVGSF..LAQL.........................PAMP..TV.....P.GL.LGAAap............vpAPA.P...APAAAP...P.PA..PA.PAA....DPP.aA.PVPDAPQPAilgq.........aalqnAF..TFFNPANFDAS....SLLGQ......-..-----SVPTFAP..PNLDFVAQMqRQFFPGMTPAQPAAA.GTDAQASDISEVRVRPE....D..........P...Y.......SQEAQMKIKS.ALEMEQ.ER...QQ...Q...AQVKD...QEQVPLLWFRMPT.......TQNQ...DA............T...E..E..KTL....E......DLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSA.....AAQ.NGD.sPYRIS......YPLSRTPIHKITRADIEQALRDDYVRRLVNK..EAQRRarnsGINTQKA.............NALKRQAKSQ.D..Q...TLSKEDIVQIMAYAYRMANEQMESEK-g...........
B4GVW6_DROPE/83-479                  ..............................................................................................................................................MLFPALGSLLRWGALFPAPTMLGAVPDSL....-QPTAAASKVVLVLADDPTA.KTRVTRQD-A.PP...--A...P......NAFGQLLAQMPnpNFAq..gwMN.PANF........NPDSFNLGqiaPNVGQA..LTNMq.......................lPPMPqfGF.....E.NI.LGAA................PPPpP...AVVPPP...P.AE..PA.PPA....APA..A.DEPAAPVAAp................nPF..SFLTPNNFDVN....QLLGQ......A..QQALPPMPPMPAmpSNVDFFSNL.RQMWPGGPPANPGPApGSDGQASDISEVRVRPE....-..........-...-.......---------A.A-----.DS...QE...N...DL-DD...KERVPLLWFRMPM.......NRQG...DE............G...E..A..KPL....E......DLRVEAKLRAFERQVIAELKMLQQIERVAKEMRSSA.....TSS.SGS..PYKVS......YPLSRTPVHKITRADIERALRDDYVRRLLHK..EAQRK....SRANH--.............AAFKRQTMPS.E..A...SMSKEDIVKIMAYAYRMATEQQSAA--qe..........
#=GC seq_cons                        ...............................................................................................................................................hFPALuSLL+WGuLFPA.olLGAlPDsL.....QPpuAASKVVLVLADDssu.KoRVsRQs....s...sss...P.............GQh....h.........Ptsh........phsshshu...spVGph..Lsph..........................shs..sh.......sh.LGtA................sP..P...sssssP...P.ss..PA.Pss....ssP..A.s.PssP.su..................sh..shhsssNhs.s....thLGp..............shPths......sFhuth.RQhhPG...h..ts..GspuQASDISEVRV+P-...........................t..hphp.po.A......pp...Qp.......t..pp...pcpVPLLWFRhPh.......sppt...st............p...p..s..Ksh....E......DL+lEAKLpAFERQVIsEL+hLQpIE+hA+pMRupA.....sup.sus..sa+ls......YPLSRTPVHKITRADIEpALRDDYVRRLlp+..EAQR+....sh.sp...............sshKRQs.sp.-..t...slSKEDIlplMAYAYRMAsEp.pt...t...........
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