#=GF ID DNAPolymera_Pol
#=GF AC PF11590.12
#=GF DE DNA polymerase catalytic subunit Pol
#=GF AU Pollington J;0000-0002-8158-8998
#=GF SE pdb_1dml
#=GF GA 26.00 26.00;
#=GF TC 26.10 26.70;
#=GF NC 25.00 21.80;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 10882068
#=GF RT The crystal structure of an unusual processivity factor, herpes
#=GF RT simplex virus UL42, bound to the C terminus of its cognate
#=GF RT polymerase.
#=GF RA Zuccola HJ, Filman DJ, Coen DM, Hogle JM;
#=GF RL Mol Cell 2000;5:267-278.
#=GF DR INTERPRO; IPR021639;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family of proteins represents the catalytic subunit, Pol,
#=GF CC of the Herpes simplex virus DNA polymerase. Pol binds UL42,
#=GF CC making up the DNA polymerase. UL42 is a processivity subunit
#=GF CC which binds to the C-terminal of Pol in a similar way that the
#=GF CC cell cycle regulator p21 binds to PCNA [1].
#=GF SQ 20
#=GS A0A0Y0AAR8_9ALPH/1184-1218 AC A0A0Y0AAR8.1
#=GS A0A068EVY1_9ALPH/1204-1244 AC A0A068EVY1.1
#=GS A0A060Q0V6_9ALPH/1194-1229 AC A0A060Q0V6.1
#=GS Q9WSY3_9ALPH/1144-1184 AC Q9WSY3.1
#=GS Q2QBE6_CHV16/1207-1242 AC Q2QBE6.1
#=GS Q19BB9_9ALPH/1174-1214 AC Q19BB9.1
#=GS DPOL_HHV11/1200-1235 AC P04293.2
#=GS L0N6J6_HHV1/1200-1235 AC L0N6J6.1
#=GS A0A1S6JLN1_HSVA1/1220-1255 AC A0A1S6JLN1.1
#=GS K9MFY2_9ALPH/1205-1240 AC K9MFY2.1
#=GS A2TIW3_9ALPH/1160-1200 AC A2TIW3.1
#=GS DPOL_HHV2H/1205-1240 AC P89453.1
#=GS F8TC24_9ALPH/1165-1205 AC F8TC24.1
#=GS A0A0U1ZCX7_9ALPH/1204-1244 AC A0A0U1ZCX7.1
#=GS Q9DPQ7_MEHV1/1159-1199 AC Q9DPQ7.1
#=GS G9CUD9_9ALPH/1174-1214 AC G9CUD9.1
#=GS E2IUD9_SHV1/1206-1241 AC E2IUD9.1
#=GS DPOL_GAHVM/1174-1214 AC Q9E6N9.1
#=GS Q805Z8_CHV1/1212-1247 AC Q805Z8.1
#=GS J9R067_9ALPH/1155-1190 AC J9R067.1
A0A0Y0AAR8_9ALPH/1184-1218 .elv----NRLKKAGFEPIG..CGI.....TEEETHQRLCTAFDILT
A0A068EVY1_9ALPH/1204-1244 ...d-EDAERLAKAGFAVVR..TGAgldpsEEEESRQRWSTAFRILT
A0A060Q0V6_9ALPH/1194-1229 ..ee--IAAKLRAAGFVAVG..AGA.....TEEEIRQRLHRAFDTLA
Q9WSY3_9ALPH/1144-1184 ..ra--YATRVARAVFAEIR..SGAglsssEEEETLQRLNRAFRILT
Q2QBE6_CHV16/1207-1242 .eet---AVRLRAAGFRAAG..AGA.....TEAETRRRLRTAFDTLA
Q19BB9_9ALPH/1174-1214 ....CSYTERVSSEMFTTIR..SGIglqvnEEEETRRKLNIAFRILT
DPOL_HHV11/1200-1235 ....DDVAARLRTAGFGAVG..AGA.....TAEETRRMLHRAFDTLA
L0N6J6_HHV1/1200-1235 ....DDVTARLRATGFGAVG..AGA.....TAEETRRMLHRAFDTLA
A0A1S6JLN1_HSVA1/1220-1255 ..ae--LAARLRGAGFARAG..AGL.....TEEETRRRLRRAFDTLA
K9MFY2_9ALPH/1205-1240 ....DDVAARLRAAGFGSAG..AGA.....TAEETRRMLHRAFDTLA
A2TIW3_9ALPH/1160-1200 ....DETAALLSSAGFAEVRlyPGMp..lsEEEENRQKLRRAFDILA
DPOL_HHV2H/1205-1240 ....DDVAARLRAAGFGPAG..AGA.....TAEETRRMLHRAFDTLA
F8TC24_9ALPH/1165-1205 ..ra--YATRVARAVFAEIR..SGAglsssEEEETLQRLNRAFRILT
A0A0U1ZCX7_9ALPH/1204-1244 ...d-EDAERLAKAGFAVVR..TGAgldpsEEEESRQRWSTAFRILT
Q9DPQ7_MEHV1/1159-1199 ...m-DCAERLPSAIFTTIK..SGAgvpvnEEEENHRKLRKAFRILT
G9CUD9_9ALPH/1174-1214 ....CSYTERVSSEMFTTIR..SGIglqvnEEEETRRKLNIAFRILT
E2IUD9_SHV1/1206-1241 ..ae--LAARMRAAGFAQIG..AGS.....TGVDTHRRLRTAFDILA
DPOL_GAHVM/1174-1214 ....CSYTERVSSEMFTTIR..SGIglqvnEEEETRRKLNIAFRILT
Q805Z8_CHV1/1212-1247 .eet---AIRLRGAGFRAAG..AGA.....TEEETRQRLRRAFDTLA
J9R067_9ALPH/1155-1190 sgtv----ARLRRAGFAVAG..AGA.....TEAETRQRLRTAFYTLA
#=GC seq_cons ......hAsRLpuAGFuslt..uGA.....pEEETRp+L+pAFchLs
//
