#=GF ID DUF16
#=GF AC PF01519.16
#=GF DE Protein of unknown function DUF16
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Pfam-B_764 (release 4.0)
#=GF GA 30.40 30.40;
#=GF TC 30.40 32.30;
#=GF NC 30.30 30.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Coiled-coil
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 8948633
#=GF RT Complete sequence analysis of the genome of the bacterium
#=GF RT Mycoplasma pneumoniae.
#=GF RA Himmelreich R, Hilbert H, Plagens H, Pirkl E, Li BC, Herrmann R;
#=GF RL Nucleic Acids Res 1996;24:4420-4449.
#=GF RN [2]
#=GF RM 16522803
#=GF RT Crystal structure of the DUF16 domain of MPN010 from Mycoplasma
#=GF RT pneumoniae.
#=GF RA Shin DH, Kim JS, Yokota H, Kim R, Kim SH;
#=GF RL Protein Sci. 2006;15:921-928.
#=GF DR INTERPRO; IPR002862;
#=GF DR SO; 0001080; coiled_coil;
#=GF CC The function of this protein is unknown. It appears to only
#=GF CC occur in Mycoplasma pneumoniae. The crystal structure revealed
#=GF CC that this domain is composed of two separated homotrimeric
#=GF CC coiled-coils [2].
#=GF SQ 31
#=GS Y104_MYCPN/3-103 AC P75565.1
#=GS Y501_MYCPN/39-113 AC P75286.1
#=GS Y524_MYCPN/40-125 AC P75254.1
#=GS A0A1M6CJZ4_9CLOT/2-77 AC A0A1M6CJZ4.1
#=GS Y130_MYCPN/39-139 AC P75345.1
#=GS R9MH93_9FIRM/34-128 AC R9MH93.1
#=GS Y013_MYCPN/179-256 AC P75100.1
#=GS Y410_MYCPN/39-146 AC P75374.1
#=GS Y138_MYCPN/39-157 AC P75260.1
#=GS Y100_MYCPN/110-181 AC P75592.1
#=GS Y655_MYCPN/97-195 AC P75136.1
#=GS Y287_MYCPN/2-116 AC P75490.1
#=GS Y344_MYCPN/86-194 AC P75434.1
#=GS A0A0Q5TCD4_9BACT/2-121 AC A0A0Q5TCD4.1
#=GS Y100_MYCPN/39-114 AC P75592.1
#=GS Y010_MYCPN/37-130 AC P75103.1
#=GS Y010_MYCPN/37-130 DR PDB; 2BA2 C; 205-285;
#=GS Y010_MYCPN/37-130 DR PDB; 2BA2 A; 5-85;
#=GS Y010_MYCPN/37-130 DR PDB; 2BA2 B; 106-185;
#=GS Y139_MYCPN/39-154 AC P75259.1
#=GS Y484_MYCPN/2-102 AC P75301.1
#=GS Y204_MYCPN/39-146 AC P75572.1
#=GS Y151_MYCPN/2-110 AC P75035.1
#=GS Y094_MYCPN/39-139 AC P75598.1
#=GS Y368_MYCPN/39-157 AC P75413.1
#=GS Y504_MYCPN/39-125 AC P75282.1
#=GS Y501_MYCPN/110-167 AC P75286.1
#=GS Y127_MYCPN/77-166 AC P75348.1
#=GS A0A0R2HHR2_9LACT/2-105 AC A0A0R2HHR2.1
#=GS Y038_MYCPN/29-115 AC P75076.1
#=GS Y137_MYCPN/43-170 AC P75261.1
#=GS Y013_MYCPN/108-216 AC P75100.1
#=GS Y283_MYCPN/40-115 AC P75494.1
#=GS Y145_MYCPN/37-164 AC P75141.1
Y104_MYCPN/3-103 ....................................eldgkf----..--------....---------------....---A..........TKADLKRVED...KVDvlfelqk....tqgeqikVQGKQIEQLTETVQKQGEQIKELQVQVK....AQGEEIKeik.......veqkAQGQTLQLILKALEGINKRLDNLES.................
Y501_MYCPN/39-113 ..........................................EFSG..KFNRQFKLnkpvIPVNTEYVTRKEFNE....YKNS..........NDQRLTKIET...TLA..................AQGEQINKLTQTVEKQGEQINQLVQ---....-------..............-------------------------vv...............
Y524_MYCPN/40-125 ...................................elrkykl----..------KP....-PVKVKYVTQEQFQE....YKDS..........NNQRLIKIET...TLA..................AQGEQI-------RIQVEQIKELQIEQK....AQGE---..............----TLKLILQTLQKMSDRLDKME-v................
A0A1M6CJZ4_9CLOT/2-77 .......................................tdq----..--------....---------------....---D..........LQHTLNQIVG...MID..................TLGKKIDRLEEKVDRIEERLDRIEERLD....RVEERLD..............RVEERLDRVEERLDRVEARLDSLE-.................
Y130_MYCPN/39-139 ..........................................EFSG..NFNRQFKLnkpvIPVNTEYVTRKEFNE....YKDS..........NDQRLIKIET...TLA..................AQGEQ-------IRIQGEQIKELQIEQK....AQSE---..............----TLKLILQTLQKMSDRLDKMD-vrldkles.........
R9MH93_9FIRM/34-128 ..................................leekldak----..--------....------------LQF....YMEK..........TNQRFDKLEN...KVE..................KVGQRLDSLEEKVEKVEQRLDSLEEKVE....KVEQRLDsle.......ekveKVEQRLDSLEEKVEKVEQRLDSLE-e................
Y013_MYCPN/179-256 ........................................kq----..--------....---------------....----..........----IEQLTE...TVK..................VQGEQIRAQGEQIKAQSEEIKEIKVEQK....AQGEQIKelq.......veqkAQGKTLQLILKTLEKMNERLEKLES.................
Y410_MYCPN/39-146 ..........................................EFSG..SFNRQFKLnkpiIPVNTEYVTRKEFNE....YKDS..........NDQRLIKIET...TLT..................AQGEQINKLTQTVEKQGEQIRELQVEQK....AQGEQIK..............AQGETLKLILQTLQKMSDRLDKID-p................
Y138_MYCPN/39-157 ..........................................EFSG..NFNRQFKLnkpvIPVNTEYVTRKEFNE....YKDS..........NDQRLTKIEN...KVD..................KLEVKVDKLEEKVDKLEAKVDKLEEKVD....KLEAKVDkleek...vdkleaKVDSGFEMLAKILAAINKRLDSIEG.................
Y100_MYCPN/110-181 .......................................vqv----..--------....---------------....----..........----------...-VL..................LHGEQINKLTQTVEKQGEQIKELQVEQK....AQGEQIKaqg.......kqikAQGKTLKSILQALGGINKRLDKID-p................
Y655_MYCPN/97-195 .......................................qpg---GpdNPNAGNKK....MPTPEEYVTRKEFNE....FKDS..........NNQRLTKIEN...KVD..................KLEVKVDKLAEIVQTQGEEIKELKVEQK....AQSE---..............----TLQLILKTLQKMNDRLDRMET.................
Y287_MYCPN/2-116 .........................................g-FSD..NLNHMEKR....---KSGYVTQKQFSE....FKDA..........NNQRLIKIET...TLA..................TQGEQLNQLIKVVILQGEQIKELQVEQK....AQGEQIKakgeqikaqseqikTQGETLKLILQALGGINKRLDKVD-p................
Y344_MYCPN/86-194 ....................................qpggpd----..DPNSGNKK....MPKPDEFVTHRQLQE....FKKDllvelheifpTKPELKRVEE...KVD..................VLFELQKAQGEQIRIQGEQIKELKVEQK....AQGE---..............----TLQLILQTLQKMNDRLDKIEG.................
A0A0Q5TCD4_9BACT/2-121 yieeridlaeislvehgkqiemiatglatlttlvytgfaemr----..--------....---------------....----..........--EEFVQVHK...RID..................NLEIRFNKLEDKVDRLEIRIDRLEVRLD....KVEARLD..............KVEERLDKIEERLDKIEERLDKIE-arldnles.........
Y100_MYCPN/39-114 ..........................................EFSG..SFNRQFKLnkpvIPVNTEYVTRKEFNE....YKVS..........NDQRLTKIET...TLA..................AQGEQINKLTQTVEKQGEQINQLVQ---....-------..............-------------------------vvl..............
Y010_MYCPN/37-130 .........................................w-LKG..VFEEIVKT....-P-GTRYVTHKQLDE...kLKNF.........vTKTEFKEFQT...VVM..................---ESFAVQNQNIDAQGEQIKELQVEQK....AQGK---..............----TLQLILEALQGINKRLDNLES.................
#=GR Y010_MYCPN/37-130 SS .........................................X-XXX..XXXXXXXX....-X-XTTB-BHHHHHH...HHTTB.........-BHHHHHHHHH...HHH..................---HHHHHHHHHHHHHHHHHHHHHHHHH....HHHH---..............----HHHHHHHHHHHHHHHHHHHC-.................
Y139_MYCPN/39-154 ..........................................EFSG..SFNRQFKLnkpvIPVNTEYVTRKEFNE....YKDS..........NDQRLTKIET...ELK..................SQGQRIQVVEDKVDRLTEVVMVQSQQIK....TQGEAMNarmd......rfesLVLKSLESIGNTLTDFGKRLDVIET.................
Y484_MYCPN/2-102 .........................................g-FYG..NLNHMEKR....---KSGYVTQKQFND....FKNS..........NNQRLIKIEN...TLV..................SQGEQISQLIKVSILQGEQINKLTETVE....KQGEQIQ..............TQGETLKLILETLQVINKRLDRLES.................
Y204_MYCPN/39-146 ..........................................EFSG..KFNRQFKLnkpvITVNTEYVTRKELNE....YKDS..........NDQRLTKIET...TLA..................AQGEQINKLTQTVEKQGEQIRELQVEQK....AQGEQIK..............AQGETLKLILQTLQKMSDRLDKID-p................
Y151_MYCPN/2-110 ..........................................EFNG..NLNHMEKR....---KSGYVTQKQFNE....YKDS..........NDQRLIKIET...TLA..................AQGEQISQLVQIVFLQGKQIKELQAEQK....AQRVEFNarmd......rfesLVLKSLESIGNTLTDFGKRFDSMET.................
Y094_MYCPN/39-139 ..........................................EFSG..NFNRQFKLnkpvIPVNTEYVTRKEFNE....YKDS..........NDQRLTKIET...TLA..................AQGEQ-------IRIQGEQIKELQIEQK....AQGETLK..............LILQTLQKMSDRLNKMDVRLDKLE-s................
Y368_MYCPN/39-157 ..........................................EFSG..SFNRQFKLnkpvIPVNTEYVTRKEFNE....YKDS..........NDQRLTKIEN...KVD..................KLEIKVDKLEKKVDKLEVKVDKLVETVN....AQGEDLNnfkve...vrgtlqSQGETLQLILQTLQGMSKRLDSVEG.................
Y504_MYCPN/39-125 ..................................yelrkykl----..------KP....-PVKVKYVTQEQFQE....YKDS..........NNQRLIKIEN...KVD..................-------KLVEIVQIHGEQI-------K....AQGE---..............----TLQLILQTLQKMSDRLDKME-kridkles.........
Y501_MYCPN/110-167 .......................................vqv----..--------....---------------....----..........----------...-VL..................LHGEQINKLTQTVEKQGEQIKELQIEQK....AQGE---..............----TLKLILQTLQKMSDRLDKME-v................
Y127_MYCPN/77-166 .........................................g-FNG..NFNHMEKR....---KSGYVTQKQFSE....FKDA..........NNQRLIKIET...TLA..................IQGEQINKLTQTVEKQGEQINQLVQVVL....LQGA---..............-------------------------sklenfkwskkhkdksl
A0A0R2HHR2_9LACT/2-105 ...................................tandamp----..--------....IPSPPDWVTQKEFQE....FKTE..........VKQNFKQIDRqfvRID..................QQFVRIDQQFKLIDIQFGKVNNRLDRIDdrldVMEKNFA..............VHEKSFKMMEKNFQTMEK-------nsdlr............
Y038_MYCPN/29-115 .........................................g-FHG..NLNHMEKG....---KSGYVTHKQLDKklevFKQ-..........---DL-----...LVE..................-LSEKF-VTKEEFRAQGKQIKELQIEQK....AQGK---..............----TLQLILEALQGINKRLDKLES.................
Y137_MYCPN/43-170 .........................................s-FNG..DFEVVTKK....-P-STKYVTHKQLDQklkeFKQDlmvelhdtfaTKADLRDSEA...RINqklea.......lvqvvlLHGEQINKLTQIVEKQGEQIRELQVEQK....AQRQEFN.............aRMDRLENLLVESIESTNKRFDSIEG.................
Y013_MYCPN/108-216 ..................................pggpddps----..---EGKQK....VSKPDKYVTHRELDE...kLK-Df........aTKADFKRVED...KVDvlf...........elqkTQGEQIKVQGEQIKAQGKQIEQLTETVK....VQGEQIR..............AQGEQIKAQSEEIKEI---------kveq.............
Y283_MYCPN/40-115 ...................................elrkykl----..------KP....-PVKVKYVTQEEFGE....FKDA..........TNQRLTKIEN...ALV..................AQGEQIRAQGEQLSQLIKVVLLQGEQIK....SQGEQIK..............-------------------------s................
Y145_MYCPN/37-164 .........................................s-LNG..VFEEIVKT....-PGKTRYVTHKQLDQklkdFKQDlmvelhdtfaTKTDLKESEA...RINqklealiqivmvqgeqikVHGEQINKLTQAVEKQGEKI-------E....AQGQQIQ..............KVNETLNFVVESLGSIHKRLDSMEG.................
#=GC SS_cons .........................................X-XXX..XXXXXXXX....-X-XTTB-BHHHHHH...HHTTB.........-BHHHHHHHHH...HHH..................---HHHHHHHHHHHHHHHHHHHHHHHHH....HHHH---..............----HHHHHHHHHHHHHHHHHHHC-.................
#=GC seq_cons ..................................................pt..Kh.....s.pscYVTpKphsE....aKss..........spQcLp+IEs...pls..................spGEQIspLtppVctQGEQIccLp.c.K....AQGEphp.................poLphIhpsLpphscRLDphE..................
//
