GenomeNet

Database: Pfam
Entry: DUF1863
LinkDB: DUF1863
Original site: DUF1863 
#=GF ID   DUF1863
#=GF AC   PF08937.12
#=GF DE   MTH538 TIR-like domain (DUF1863)
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1eiw
#=GF GA   21.20 21.20;
#=GF TC   21.20 21.20;
#=GF NC   21.10 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   10964569
#=GF RT   Structure-based functional classification of hypothetical
#=GF RT   protein MTH538 from Methanobacterium thermoautotrophicum. 
#=GF RA   Cort JR, Yee A, Edwards AM, Arrowsmith CH, Kennedy MA; 
#=GF RL   J Mol Biol. 2000;302:189-203.
#=GF DR   INTERPRO; IPR015032;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain adopts the flavodoxin fold, that is, five parallel
#=GF CC   beta-strands and four helical segments. The structure is a
#=GF CC   three-layer sandwich with alpha-1 and alpha-4 on one side of the
#=GF CC   beta-sheet, and alpha-2 and alpha-3 on the other side. Probable
#=GF CC   role in signal transduction as a phosphorylation-independent
#=GF CC   conformational switch protein [1]. This domain is similar to 
#=GF CC   the TIR domain.
#=GF SQ   906
#=GS U7UTD8_9FIRM/4-117        AC U7UTD8.1
#=GS A0A1I7N2I0_9RHIZ/3-122    AC A0A1I7N2I0.1
#=GS A0A368VYD5_9ACTN/7-137    AC A0A368VYD5.1
#=GS A0A1G8MQI9_9MICC/5-119    AC A0A1G8MQI9.1
#=GS A0A1Z4VQ68_9GAMM/3-115    AC A0A1Z4VQ68.1
#=GS A0A1J5TYI7_9GAMM/2-117    AC A0A1J5TYI7.1
#=GS A6QC41_SULNB/5-199        AC A6QC41.1
#=GS A0A2S1LGQ0_9FLAO/5-129    AC A0A2S1LGQ0.1
#=GS A0A327LRM2_9RHOB/6-128    AC A0A327LRM2.1
#=GS E0IF39_9BACL/4-117        AC E0IF39.1
#=GS Q12I74_SHEDO/3-119        AC Q12I74.1
#=GS A5Z7Z7_9FIRM/3-129        AC A5Z7Z7.1
#=GS D8P9K2_9BACT/24-141       AC D8P9K2.1
#=GS A0A3S2W944_9GAMM/10-146   AC A0A3S2W944.1
#=GS I0WBT4_9FLAO/5-125        AC I0WBT4.1
#=GS A0A2I0MZW0_9CLOT/81-300   AC A0A2I0MZW0.1
#=GS A3DI79_CLOTH/7-123        AC A3DI79.1
#=GS G2Z7J3_FLABF/3-139        AC G2Z7J3.1
#=GS A0A370X5C3_9GAMM/12-216   AC A0A370X5C3.1
#=GS A0A2I0R468_9FLAO/18-140   AC A0A2I0R468.1
#=GS A0A1H6BMQ6_9SPHI/12-252   AC A0A1H6BMQ6.1
#=GS A0A373NQR8_9FIRM/29-218   AC A0A373NQR8.1
#=GS A0A080M2C6_9PROT/3-115    AC A0A080M2C6.1
#=GS A0A1D9NYN0_9FIRM/5-192    AC A0A1D9NYN0.1
#=GS A0A0V8JGM0_9BACI/3-125    AC A0A0V8JGM0.1
#=GS U2YP28_9SPHN/5-113        AC U2YP28.1
#=GS W0TQW6_9GAMM/7-121        AC W0TQW6.1
#=GS A0A2T6DEW4_9BACT/108-306  AC A0A2T6DEW4.1
#=GS A0A0N8GSQ2_9CHLR/4-113    AC A0A0N8GSQ2.1
#=GS Q2NGB5_METST/3-120        AC Q2NGB5.1
#=GS A0A0J1H4N9_9GAMM/4-115    AC A0A0J1H4N9.1
#=GS A0A3N5Y5B3_9ALTE/4-133    AC A0A3N5Y5B3.1
#=GS A0A1H8ZK33_9FIRM/5-197    AC A0A1H8ZK33.1
#=GS A0A0S7C484_9BACT/5-121    AC A0A0S7C484.1
#=GS A0A3S3UTL1_9GAMM/6-121    AC A0A3S3UTL1.1
#=GS G5GFQ7_9FIRM/13-229       AC G5GFQ7.1
#=GS A0A3N0V6P6_9PROT/6-129    AC A0A3N0V6P6.1
#=GS A0A1Y4TVD9_9FIRM/3-125    AC A0A1Y4TVD9.1
#=GS A0A399RG30_9RHOB/2-123    AC A0A399RG30.1
#=GS A0A1V3Q979_9GAMM/16-215   AC A0A1V3Q979.1
#=GS D7CIL4_SYNLT/3-144        AC D7CIL4.1
#=GS A0A0A6VZ89_9MICC/4-113    AC A0A0A6VZ89.1
#=GS H0R6A8_9ACTN/10-134       AC H0R6A8.1
#=GS F5SXS4_9GAMM/5-112        AC F5SXS4.1
#=GS A0A0K1W2V8_9MOLU/4-126    AC A0A0K1W2V8.1
#=GS A0A1G9RDW0_9FIRM/4-128    AC A0A1G9RDW0.1
#=GS D0GMY6_9FUSO/3-125        AC D0GMY6.1
#=GS A0A1X0DRR1_9MYCO/3-116    AC A0A1X0DRR1.1
#=GS A0A1X6WLL2_9ENTE/3-122    AC A0A1X6WLL2.1
#=GS A0A1Q8BZD0_9PSEU/5-128    AC A0A1Q8BZD0.1
#=GS A5V4E5_SPHWW/27-213       AC A5V4E5.1
#=GS A0A0Q6LZW5_9BURK/18-221   AC A0A0Q6LZW5.1
#=GS A0A087MFN7_9GAMM/7-197    AC A0A087MFN7.1
#=GS A0A1B8WNW1_9BACI/24-145   AC A0A1B8WNW1.1
#=GS A5Z7Z9_9FIRM/3-151        AC A5Z7Z9.1
#=GS I3Z8B9_BELBD/5-125        AC I3Z8B9.1
#=GS A0A177N7J6_9GAMM/3-120    AC A0A177N7J6.1
#=GS U7USU3_9FIRM/3-119        AC U7USU3.1
#=GS Q03QQ3_LACBA/2-119        AC Q03QQ3.1
#=GS A0A366H0A0_9BURK/5-119    AC A0A366H0A0.1
#=GS G2NNX9_STREK/3-201        AC G2NNX9.1
#=GS A0A0S7C285_9BACT/8-129    AC A0A0S7C285.1
#=GS A0A0E3Z9G0_9FUSO/3-120    AC A0A0E3Z9G0.1
#=GS A0A1M6KWT5_MALRU/2-105    AC A0A1M6KWT5.1
#=GS F0JBR8_DESDE/9-203        AC F0JBR8.1
#=GS A0A3N5Y683_9ALTE/1-55     AC A0A3N5Y683.1
#=GS A0A2G4YQT6_9PROT/25-134   AC A0A2G4YQT6.1
#=GS A0A396KYR6_9FIRM/187-385  AC A0A396KYR6.1
#=GS A0A1H6VRI8_9GAMM/12-208   AC A0A1H6VRI8.1
#=GS A0A2X4PGG9_9PORP/3-115    AC A0A2X4PGG9.1
#=GS A0A0T5NZP7_9RHOB/1-126    AC A0A0T5NZP7.1
#=GS A0A1D3TV11_9FIRM/3-127    AC A0A1D3TV11.1
#=GS A0A1B4V7Q6_9GAMM/4-118    AC A0A1B4V7Q6.1
#=GS A0A2J6MQK6_9BURK/8-139    AC A0A2J6MQK6.1
#=GS A0A099XRV9_9FLAO/5-129    AC A0A099XRV9.1
#=GS A0A1B9Z2H8_9BRAD/3-114    AC A0A1B9Z2H8.1
#=GS A0A239IHR2_9ACTN/4-128    AC A0A239IHR2.1
#=GS A0A090HWQ9_9FIRM/4-111    AC A0A090HWQ9.1
#=GS A0A1I5PSA8_9FIRM/3-120    AC A0A1I5PSA8.1
#=GS A0A291QXZ7_9BACT/3-128    AC A0A291QXZ7.1
#=GS A0A291QB50_9ACTN/1-60     AC A0A291QB50.1
#=GS A0A1K1LLL0_9BACT/5-119    AC A0A1K1LLL0.1
#=GS A0A3A8YZT1_9BACT/2-120    AC A0A3A8YZT1.1
#=GS A0A2W7NU35_9BACT/7-127    AC A0A2W7NU35.1
#=GS F9EDQ5_9ACTO/10-134       AC F9EDQ5.1
#=GS A0A220W8M2_9SPHN/25-205   AC A0A220W8M2.1
#=GS E0E1T3_9FIRM/4-117        AC E0E1T3.1
#=GS A0A1I6BFZ6_9BACT/3-115    AC A0A1I6BFZ6.1
#=GS A0A367F6D6_9ACTN/12-202   AC A0A367F6D6.1
#=GS A0A410P789_9BACT/3-131    AC A0A410P789.1
#=GS A0A1Y0M8N1_9FLAO/4-115    AC A0A1Y0M8N1.1
#=GS A0A164NTI7_9NOCA/13-258   AC A0A164NTI7.1
#=GS A0A328S8A9_9EURY/6-122    AC A0A328S8A9.1
#=GS M7MY24_9FLAO/8-130        AC M7MY24.1
#=GS C4IHA7_CLOBU/3-152        AC C4IHA7.1
#=GS A0A1B9F0F0_9ACTN/11-132   AC A0A1B9F0F0.1
#=GS A0A192WWR8_9BACT/35-224   AC A0A192WWR8.1
#=GS A0A2T4U6W6_9BACI/3-114    AC A0A2T4U6W6.1
#=GS N1MQT1_9SPHN/46-240       AC N1MQT1.1
#=GS W0GM85_9MOLU/1-62         AC W0GM85.1
#=GS W0DT20_9GAMM/5-115        AC W0DT20.1
#=GS A0A231V1P8_9RHIZ/5-127    AC A0A231V1P8.1
#=GS A0A3A8WGC3_9BACT/3-151    AC A0A3A8WGC3.1
#=GS A6T1M3_JANMA/3-120        AC A6T1M3.1
#=GS A0A1H5GS75_9FLAO/4-129    AC A0A1H5GS75.1
#=GS A0A1H9DPS9_9GAMM/7-193    AC A0A1H9DPS9.1
#=GS A0A1I1H7N0_9FIRM/3-191    AC A0A1I1H7N0.1
#=GS A0A366H183_9BURK/3-120    AC A0A366H183.1
#=GS A7HHH7_ANADF/34-147       AC A7HHH7.1
#=GS U1Q2A5_9ACTO/4-292        AC U1Q2A5.1
#=GS A0A410GBC8_9BURK/6-120    AC A0A410GBC8.1
#=GS A0A2V1JZZ0_9BORD/8-123    AC A0A2V1JZZ0.1
#=GS A0A1Z4VQ47_9GAMM/2-121    AC A0A1Z4VQ47.1
#=GS A0A437QYN7_9PROT/10-140   AC A0A437QYN7.1
#=GS F2LFI5_BURGS/3-121        AC F2LFI5.1
#=GS A0A0T2IDP9_9MICO/4-122    AC A0A0T2IDP9.1
#=GS A0A219AH54_9FLAO/3-119    AC A0A219AH54.1
#=GS A0A1N7E6J3_9ACTN/8-203    AC A0A1N7E6J3.1
#=GS B7AWL8_9FIRM/4-127        AC B7AWL8.1
#=GS A0A1C3EPH0_9GAMM/2-132    AC A0A1C3EPH0.1
#=GS A0A0N0J4P3_9PROT/6-195    AC A0A0N0J4P3.1
#=GS F9Z9X4_ODOSD/7-191        AC F9Z9X4.1
#=GS A6QC47_SULNB/3-134        AC A6QC47.1
#=GS G8SD34_ACTS5/3-197        AC G8SD34.1
#=GS A0A1G7DMR0_9FLAO/3-117    AC A0A1G7DMR0.1
#=GS A0A231HHD3_9BURK/5-117    AC A0A231HHD3.1
#=GS A0A2U1ELH5_9MICO/4-251    AC A0A2U1ELH5.1
#=GS F8C2H3_THEGP/3-120        AC F8C2H3.1
#=GS W2BWX4_9FIRM/3-125        AC W2BWX4.1
#=GS A0A1S8CSY5_9GAMM/4-123    AC A0A1S8CSY5.1
#=GS Q4ZA72_9CAUD/3-119        AC Q4ZA72.1
#=GS G8SLP8_ACTS5/4-194        AC G8SLP8.1
#=GS A0A2U1BDB3_9FIRM/3-144    AC A0A2U1BDB3.1
#=GS D9QIQ3_BRESC/11-197       AC D9QIQ3.1
#=GS A0A2U1G1C2_9SPHN/3-189    AC A0A2U1G1C2.1
#=GS Q1QQ24_NITHX/6-137        AC Q1QQ24.1
#=GS A0A2A3HCX2_9ACTN/5-117    AC A0A2A3HCX2.1
#=GS A0A1G5K1M6_9RHOB/13-216   AC A0A1G5K1M6.1
#=GS A0A090RUD0_9VIBR/5-140    AC A0A090RUD0.1
#=GS A0A2A4G0E2_9SPHN/10-192   AC A0A2A4G0E2.1
#=GS D2B0U0_STRRD/22-145       AC D2B0U0.1
#=GS A0A1H3WKE0_9GAMM/3-118    AC A0A1H3WKE0.1
#=GS A0A416Q257_9FIRM/7-131    AC A0A416Q257.1
#=GS A0A1X6Z2U4_9RHOB/8-125    AC A0A1X6Z2U4.1
#=GS A0A429SBN2_9ACTN/10-132   AC A0A429SBN2.1
#=GS A0A1Y2QM15_9SPHN/6-186    AC A0A1Y2QM15.1
#=GS A0A1H3FJ75_9RHOB/14-132   AC A0A1H3FJ75.1
#=GS A0A1Q2CFT1_9ACTN/3-116    AC A0A1Q2CFT1.1
#=GS A0A221AI79_9BURK/3-121    AC A0A221AI79.1
#=GS A0A402CUU4_9BACT/6-122    AC A0A402CUU4.1
#=GS L8N710_9CYAN/3-121        AC L8N710.1
#=GS A0A2N9JE64_9ACTN/3-118    AC A0A2N9JE64.1
#=GS A0A3G3IKC8_9GAMM/3-137    AC A0A3G3IKC8.1
#=GS A0A0R2LY77_9LACO/2-118    AC A0A0R2LY77.1
#=GS A0A1L6JHC8_9SPHN/3-119    AC A0A1L6JHC8.1
#=GS A0A3E0DZG5_9FLAO/3-122    AC A0A3E0DZG5.1
#=GS A0A1H3I6L3_9FIRM/5-197    AC A0A1H3I6L3.1
#=GS A0A3N4YQM2_9MICO/21-271   AC A0A3N4YQM2.1
#=GS A0A1I4NAQ1_9BACL/3-123    AC A0A1I4NAQ1.1
#=GS A0A2P7QLS5_9SPHN/11-190   AC A0A2P7QLS5.1
#=GS A0A1V1W401_9ACTN/1-117    AC A0A1V1W401.1
#=GS D2AYH2_STRRD/37-240       AC D2AYH2.1
#=GS A0A2G5KKH3_9FLAO/5-131    AC A0A2G5KKH3.1
#=GS A0A0E9MT72_9SPHN/21-179   AC A0A0E9MT72.1
#=GS A0A369PFB3_9GAMM/3-114    AC A0A369PFB3.1
#=GS A0A1Z5HE76_9GAMM/3-118    AC A0A1Z5HE76.1
#=GS A0A1R3U2U2_9RHIZ/3-121    AC A0A1R3U2U2.1
#=GS A0A1X0UU91_9NOCA/5-117    AC A0A1X0UU91.1
#=GS A0A372MKH7_9SPIO/17-137   AC A0A372MKH7.1
#=GS A0A0X3TBP1_9GAMM/5-116    AC A0A0X3TBP1.1
#=GS A0A316C733_PSESE/7-121    AC A0A316C733.1
#=GS F4QS64_9CAUL/13-191       AC F4QS64.1
#=GS A0A0D7EMI2_RHOPL/5-117    AC A0A0D7EMI2.1
#=GS A0A239P436_9ACTN/4-109    AC A0A239P436.1
#=GS A0A090ZVW0_PAEMA/3-121    AC A0A090ZVW0.1
#=GS A0A0J7XZB5_9SPHN/39-238   AC A0A0J7XZB5.1
#=GS A0A2S7T182_9BACT/3-118    AC A0A2S7T182.1
#=GS Q8RFH6_FUSNN/14-306       AC Q8RFH6.1
#=GS A0A3M9MTS4_9BACT/3-111    AC A0A3M9MTS4.1
#=GS A0A1G6IH29_9SPHN/68-252   AC A0A1G6IH29.1
#=GS A0A1Y4M7U9_9FIRM/529-642  AC A0A1Y4M7U9.1
#=GS A0A2P2F2Q1_9FIRM/4-129    AC A0A2P2F2Q1.1
#=GS A0A1I4MZR4_9FIRM/4-117    AC A0A1I4MZR4.1
#=GS A0A1H3E7N5_9FLAO/61-179   AC A0A1H3E7N5.1
#=GS A0A432WMQ7_9GAMM/5-124    AC A0A432WMQ7.1
#=GS A0A127FBI6_STEDE/10-125   AC A0A127FBI6.1
#=GS A0A2T6BZZ4_9FLAO/2-117    AC A0A2T6BZZ4.1
#=GS A0A150YBS6_9FIRM/30-136   AC A0A150YBS6.1
#=GS A0A2Z5YYI8_9SPHN/3-117    AC A0A2Z5YYI8.1
#=GS A0A1S2QZ67_9BACI/3-123    AC A0A1S2QZ67.1
#=GS A0A2H5ZQC7_9BACT/4-115    AC A0A2H5ZQC7.1
#=GS A0A1I1BVD3_9PSEU/5-128    AC A0A1I1BVD3.1
#=GS A0A369Q360_9SPHN/12-200   AC A0A369Q360.1
#=GS A0A1H1R2W8_9PSED/3-114    AC A0A1H1R2W8.1
#=GS A0A229UMC4_9BACL/4-118    AC A0A229UMC4.1
#=GS A0A2W4E6Q9_9RHIZ/6-120    AC A0A2W4E6Q9.1
#=GS R7CQY3_9FIRM/4-117        AC R7CQY3.1
#=GS A0A1A5YJ39_9BACL/3-109    AC A0A1A5YJ39.1
#=GS B1C2S7_9FIRM/3-73         AC B1C2S7.1
#=GS A0A3N2BB35_9MICO/3-115    AC A0A3N2BB35.1
#=GS A0A1V3PSF8_9GAMM/12-212   AC A0A1V3PSF8.1
#=GS A0A143XV52_9FIRM/6-191    AC A0A143XV52.1
#=GS A0A1B1AMI8_9CAUL/26-144   AC A0A1B1AMI8.1
#=GS A0A495KNN9_9FLAO/24-138   AC A0A495KNN9.1
#=GS A0A2G1VTY1_9FLAO/10-118   AC A0A2G1VTY1.1
#=GS I4N4P9_9PSED/4-119        AC I4N4P9.1
#=GS A0A0K2B1A3_STRA7/11-197   AC A0A0K2B1A3.1
#=GS A0A1I0J984_9BACT/4-119    AC A0A1I0J984.1
#=GS B2ILB6_BEII9/5-119        AC B2ILB6.1
#=GS A0A1K1LLI1_9BACT/5-117    AC A0A1K1LLI1.1
#=GS A0A2N9JEU6_9ACTN/14-136   AC A0A2N9JEU6.1
#=GS A0A0M2XNZ7_9SPHI/7-137    AC A0A0M2XNZ7.1
#=GS A0A372J4K6_9ACTN/25-148   AC A0A372J4K6.1
#=GS A0A371X3R1_9RHIZ/3-118    AC A0A371X3R1.1
#=GS A0A1H0VTY2_9DELT/25-137   AC A0A1H0VTY2.1
#=GS A0A0Q6BAA5_9PROT/3-116    AC A0A0Q6BAA5.1
#=GS A0A1B8JA65_9HELI/5-123    AC A0A1B8JA65.1
#=GS A0A0J6SC77_9RHIZ/5-124    AC A0A0J6SC77.1
#=GS A0A0M7AE64_9RHOB/5-124    AC A0A0M7AE64.1
#=GS C4IHA8_CLOBU/3-138        AC C4IHA8.1
#=GS B2IJM1_BEII9/5-121        AC B2IJM1.1
#=GS A0A3L7DV61_9GAMM/9-208    AC A0A3L7DV61.1
#=GS K6XVC9_9ALTE/14-215       AC K6XVC9.1
#=GS A0A1R3U318_9RHIZ/3-123    AC A0A1R3U318.1
#=GS R6BYU7_9CLOT/11-211       AC R6BYU7.1
#=GS A0A1N7AV96_9GAMM/4-123    AC A0A1N7AV96.1
#=GS A0A1Y0M6G4_9FLAO/5-124    AC A0A1Y0M6G4.1
#=GS A0A098SQK5_9PSED/5-128    AC A0A098SQK5.1
#=GS I4B4D8_TURPD/7-127        AC I4B4D8.1
#=GS A0A238XQ96_9FLAO/2-102    AC A0A238XQ96.1
#=GS Q1JX43_DESA6/17-264       AC Q1JX43.1
#=GS A0A1T1IDW4_9PSED/3-115    AC A0A1T1IDW4.1
#=GS J9RDV6_9ACTN/29-149       AC J9RDV6.1
#=GS D9SG05_GALCS/5-133        AC D9SG05.1
#=GS A0A1X3P4T0_9MICC/5-126    AC A0A1X3P4T0.1
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A0A238JHS1_9RHOB/3-129               ..............................................YRIFISHAWAYRE...........-TY.W.SI.R.A.MLDK.A.T..A.TY.S...D...-....-.F..D..Y...V...D...Y..S.I....P...D........H.N.P.....I......lSTKGA..LL.....T.gPR.LLAK.AI.QTRID..QSS..VVLVPARM......F........V......N......H..........S..........D...........W......V..L..K.E.....I..D......................................................................................................................................................................Y.A.IA..............KRYR.VI.A.LRSRSTLRVP--TGL.......IQRVGSS----idan.....................................................................................................................................................
A0A2T7G3S1_9RHOB/5-61                ...........................................qgg-------------...........---.-.--.-.-.----.-.-..-.--.-...-...-....-.-..-..-...-...-...-..-.-....-...-........-.-.-.....-.......-----..--.....-..--.----.--.-----..---..-LLILIGE......K........T.....kN......L..........Y..........K...........F......V..R..W.E.....I..D......................................................................................................................................................................L.A.IE..............LELP.II.A.VNLNNSRFQD-----.......-----------elcppiirdkcv.............................................................................................................................................
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S6A9W1_SULDS/23-141                  ..............................................RKIFVSYHHGNDQ...........AYY.D.GF.S.R.FFHD.Q.Y..E.AV.F...D...N....S.L..-..-...-...-...-..-.-....-...-........-.-.-.....-.......DRGID..SD.....N..AQ.YVMQ.RIrDKHIT..GTS..CTVVLIGA......Q........T......H......Q..........R..........K...........Y......V..D..W.E.....I..K......................................................................................................................................................................A.T.LD..............KQHG.LV.G.IVLPNHQKTNDGKIV......vPERFH------cnvctr...................................................................................................................................................
C6J5V9_9BACL/6-141                   ..............................................RKIFISYKYSDSNvyp.....lnnDYS.T.TV.R.H.YVDE.L.Q..D.KLkE...D...D....H.I..N..K...G...E...A..D.G....E...D........L.S.E.....F.......K----..--.....-..DE.TIWT.KL.KDKIF..DSS..ITIVFISK......Nmks..afvS......E......E..........D..........Q...........W......I..P..W.E.....I..S......................................................................................................................................................................Y.S.LKeltr.....ngrtsSANA.ML.A.VVLPDKNNS------.......-----------yeyfiqdn.................................................................................................................................................
A0A2S5A2F0_9SPHI/24-138              .............................hatkdfcyysmlkawkg-------------...........---.-.--.-.-.----.-.-..-.--.-...-...-....-.A..D..T...S...F...P..F.N....N...A........H.D.T.....T......yNVRDN..SD.....W..ES.TLKP.RL.RERLR..NSK..NIVMFLGS......D........T......L......N..........S..........R...........A......L..R..E.E.....I..D......................................................................................................................................................................Y.G.IN.............tLGLP.II.V.IYPNLKNNSDLLNGD.......KTALNNTV---kal......................................................................................................................................................
D5X8H7_THEPJ/4-129                   ..............................................KKVFVSFDYENDR...........-QY.K.FL.M.Q.AWDA.N.-..-.--.-...-...P....D.F..D..F...-...-...-..-.-....Y...F........T.D.H.....S.......SQEIN..SN.....N..IA.VVKA.AL.TRKIN..SAT..HTFVIIGK......E........A......N......KlhkehkligfR..........N...........W......I..N..F.E.....I..N......................................................................................................................................................................R.S.KA..............NGNK.IL.A.IKLDSRYESP--E--.......-----------elmgagaawamkf............................................................................................................................................
A0A1D9P125_9FIRM/5-197               ..............................................YNAFISYKHADLD...........NKV.A.AL.I.E.KDLE.R.Y..H.IP.K...K...L....Q.K..K..T...-...-...-..G.Y....K...K........I.E.R.....I......fRDTDE..LP.....I..TS.DLSS.TI.EEALA..NSE..YLIVLCST......N........T......H......L..........S..........T...........W......V..E..R.E.....I..D......................................................................................................................................................................I.F.LRn............hTRDQ.IF.T.V--------------.......-----------iadgephdvmpkvlqtrevvrttadgheetvvedveplacdyrlsrkevkstevprlvsamigcnynelmdrqrqykmkrltaaaaav.................................................................
Q122B7_POLSJ/5-119                   ..............................................RNIFISHIHADDS...........-RL.Q.PL.K.D.LLNQ.S.G..F.EA.R...D...G....S.I..N..S...-...-...-..-.-....-...-........-.-.-.....-.......SNPNN..AS.....S..PD.YIKS.SIlAPRIQ..WAS..VLVVLISQ......N........T......Q......H..........S..........E...........Y......V..N..W.E.....I..E......................................................................................................................................................................Y.A.EK..............QGKR.IV.G.VWDHGAGQCDI----.......PEALDKYADAI.........................................................................................................................................................
A3U3D8_PSEBH/4-117                   ............................................pr--TFVGFSSTDIH...........-YY.R.LM.L.A.W-KQ.-.-..-.--.-...H...E....R.I..D..F...N...F...A..N.C....Q...L........A.Q.E.....I.......NSENE..A-.....-..--.YIKR.KC.RERID..LAG..TFAVLIGQ......D........T.....rS......K..........H..........K...........Y......V..R..W.E.....M..E......................................................................................................................................................................V.A.RE..............RGCR.II.G.INLNGSRYMEE----.......-----------atcppiikgi...............................................................................................................................................
A0A1G8UXN0_9FIRM/5-204               ..............................................YDAFISYRHSELD...........KFV.A.--.-.-.TTLH.K.K..L.ES.F...K...L....P.K..N..V...K...S...P..TgK....K...K........I.E.R.....V......fRDQDE..LP.....L..AS.NLSD.PI.TEALE..NSD..YLLVICTP......R........L......P......E..........S..........E...........W......C..K..K.E.....I..Etfiklhgrdkvlavlaegepeesfpealtkeayev................................................................................................inpdgtretkyrifeplaadvrgknnkaikkamndA.I.LR..............ICAA.MF.G.LNYDELKQRHKERAM.......-----------rrtisivsaiaaa............................................................................................................................................
A0A0N8W4A9_9RHOB/5-132               ..............................................KNVFISHHHGDDK...........-HV.D.KF.T.Q.LMRK.N.G..S.DV.R...N...S....S.V..R..M...K...P...A..N.Q....R...R........M.D.K.....G.......RVKDE..--.....-..--.TIKR.LL.RMKMN..WAS..TVVVLIGP......K........T......H......T..........R..........P...........W......V..N..W.E.....I..S......................................................................................................................................................................Q.A.NR..............LGKR.IV.G.VYLHGGSKANL----.......-----------pkafddyghalvkwnpksi......................................................................................................................................
A0A1B6ZBB7_9SPHN/16-198              .............................................f-RAFVSYSHADAA...........-IA.R.KL.H.R.KIEN.-.Y..R.LP.A...R...L....Q.G..-..D...G...E...L..T.G....H...D........Q.N.HgrlgkI......fRDRED..LP.....A..AQ.DLSE.AV.KQALT..KSE..ALIVLCSP......D........A......Q......A..........S..........P...........W......V..A..Q.E.....I..Elfrslhpdrpilaalirgepaeaf......................................................................................................................papllqgreplaadlrkqgdgwrlG.F.LK..............IVAG.IA.G.IPLDALVQRDATRRIr.....rVMAVT------gsalia...................................................................................................................................................
L0JTV7_NATP1/3-125                   .............................................r-TTFFSFHYDNDI...........WRA.S.QV.R.N.SDVV.N.D..S.ID.-...-...-....-.-..E..S...G...F...I..D.G....A...S........W.E.S.....I.......KRDGD..D-.....-..--.AVRD.WI.NRNMK..GCS..VTVVLIGS......E........T......Y......D..........R..........K...........W......V..N..Y.E.....I..E......................................................................................................................................................................K.S.YQ..............EDMG.LV.G.VRIHKIRDKDENRDRr.....gKNP--------lskyqdsn.................................................................................................................................................
A0A1H7DDD3_9SPHN/5-117               ............................................kv--LFIAFAIEDER...........-QR.D.FL.K.G.QSLH.P.R..Q.PF.E...F...I....D.M..-..-...-...-...-..-.-....-...-........-.-.S.....V.......KEPYD..K-.....-..--.DWKD.RV.RTRIK..RSH..GVIVLVSK......N........S......A......A..........S..........T...........G......Q..K..W.E.....I..Q......................................................................................................................................................................C.A.QE..............EGKP.IQ.G.IYAYKDDR-------.......-----------asiagvstvawsdanit........................................................................................................................................
A0A428MG65_9BACT/8-196               .............................................y-TAFVSYRRLPKD..........tGWA.E.WL.V.G.ALSD.F.E..T.PE.A...L...R....R.R..G..T...-...-...-..-.P....K...K........I.G.R.....L......fRDEGD..LA.....A..SG.DLSG.EL.KAALW..DSD..YLIVVCSP......E........T......P......K..........S..........N...........W......V..R..A.E.....I..Al....................................................................................................................................................................fR.H.WG..............RADR.IL.A.LLIEGA---------.......-----------peesypellrqyrmvgegrdtvmelivpagadvtprqnkteqelkdlardrilsallgcsfaelrqsleaerrsetvva..........................................................................
A0A0J6NJ90_9NEIS/3-115               ..............................................RKVFYSFHFDNDV...........MRV.H.QI.R.N.MGIL.D.G..D.EP.A...N...-....-.-..-..-...-...-...-..-.P....N...T........W.E.Q.....I.......KRSEQ..G-.....-..--.-VKN.WI.DKNLH..GKS..CLVVLIGS......Q........T......A......N..........R..........P...........W......V..K..Y.E.....I..Q......................................................................................................................................................................R.A.WE..............LGKA.VV.G.VHIHRLN-CP-----.......-----------qngfgtkganpfdq...........................................................................................................................................
A0A1M5F2G0_9BACT/4-123               ..........................................kktv----CSFDYENDR...........IYY.N.LL.E.A.WNKN.-.-..-.PN.I...D...-....-.-..-..F...-...H...I..S.D....C...T........P.D.E.....I.......QTAS-..--.....-..VA.IIKN.VL.SRKIG..EAN..YMIAIIGK......H........S......N......DlhknheeigyR..........N...........W......Q..S..Y.E.....I..E......................................................................................................................................................................K.N.YE..............KRNG.LV.V.VTLDSS---------.......-----------csiplacygkga.............................................................................................................................................
A0A1Y4TVG6_9FIRM/3-151               ..............................................KKVFVSYKYKDNDv.........qMMP.N.VT.Q.P.TWPC.D.Y..V.DY.I...K...N....K.V..-..L...C...D...D..D.I....Y...K........G.E.K.....S.......DEDIS..SW.....S..ED.AIWN.HL.KNKIY..DST..ITIVLISPn...mkE........Tg...kwQ......R..........S..........Q...........W......I..P..W.E.....I..S......................................................................................................................................................................F.S.VRettr.....nnrtsHRNA.LL.A.VILPDKRGS------.......-----------ydyynknnlfpilksnieng.....................................................................................................................................
D6D3A2_9BACE/2-120                   ..............................................HKVFVSFHHANDQ...........KYK.E.GL.V.S.WAEK.-.N..K.VF.I...D...G....S.V..D..M...-...-...-..-.-....-...-........-.G.E.....I......pEDWDD..Q-.....-..--.KIRE.YIrDEHLK..DTT..VTILLVGT......E........T......K......N..........R..........K...........H......I..D..W.E.....L..Y......................................................................................................................................................................S.S.MYdg.........tvnKKSG.II.V.ILLPSVKS-------.......-----------eyytcahssektf............................................................................................................................................
A0A371S7I0_9BACI/4-115               .............................................p-RAFISFDFDHND...........TDK.T.LF.I.G.QSKN.S.-..-.--.-...K...-....-.V..-..-...-...P...F..S.I....Q...D........W.S.A.....K.......SSMPQ..S-.....-..--.KWEA.IV.EEKIK..KTN..MVIVLVGK......Y........M......A......S..........A..........T...........G......V..K..K.E.....I..K......................................................................................................................................................................M.A.KE..............NNVP.IF.G.VYIGGADSN------.......-----------snlpdgltrsrvv............................................................................................................................................
N2BBC1_9FIRM/4-126                   ..............................................KKVCVSFDYEHDK...........HYY.Y.LL.A.A.WNNN.-.-..-.--.-...-...P....N.I..N..F...-...-...-..G.I....N...D........C.T.P.....S.......EIQSE..S-.....-..VS.KIKQ.VL.STKIG..QAN..YMVAIIGE......H........S......T......DthpdsgeidyN..........N...........W......Q..S..Y.E.....I..A......................................................................................................................................................................K.N.HE..............KKNG.LV.V.VKLDSSYS-------.......-----------apdecynigtkwv............................................................................................................................................
V6DZ28_9EURY/1-97                    .........................................mtskd-------------...........---.-.--.-.-.----.-.-..-.--.-...-...-....R.E..A..A...G...F...F..D.A....A...E........Q.E.T.....I.......KQATD..E-.....-..--.KIRH.WI.NEQLQ..GTS..VTVVLIGN......E........T......A......E..........R..........D...........W......I..H..Y.E.....I..K......................................................................................................................................................................K.S.IE..............RGNG.IV.G.VKIHSLNDKESN---.......-----------tdfsgtnplkkfv............................................................................................................................................
A0A3N2QH68_9ALTE/4-117               ..............................................RNCFYSFHYLPDN...........WRA.G.TV.R.S.IGAI.D.G..N.KP.T...T...-....-.-..-..-...-...-...-..-.D....N...N........W.E.E.....V.......KKGGD..S-.....-..--.AIKK.WI.ADEMS..GKS..CVVVLVGS......N........T......A......G..........R..........K...........W......I..N..H.E.....I..I......................................................................................................................................................................K.G.WD..............DGKG.VV.G.IYIHGLKDSN---GN.......ISTKGDNP---fds......................................................................................................................................................
W0EVS0_9BACT/3-145                   ..............................................HKIFISYKYGDTSvehl..ertpwYES.T.KV.R.H.YVDE.L.Q..D.KL.E...D...D....DlI..N..K...G...E...L..D.G....E...D........L.S.N.....F.......K----..--.....-..DS.TVES.KL.RNKIF..DSS..ITIVLISPnmkelnK........S......E......D..........D..........Q...........W......I..P..W.E.....V..S......................................................................................................................................................................Y.S.LRettr.....ndrtsRRNG.IL.A.VVLPDINGRY-----.......-----------dymlepkrccq..............................................................................................................................................
A0A381E8B4_9GAMM/3-147               .............................................n-KIFISYKYADDS...........--V.K.QL.-.-.-PSA.S.Y..H.AP.T...T...A....R.H..Y..V...NiiqQ...K..L.E....R...D........G.T.H.....Ink...geLDNED..LSe...fR..DD.TIRS.HL.ARKIF..DSS..VTIVLMSP......N........MrefhvpE......R..........D..........Q...........W......I..P..W.E.....I..S......................................................................................................................................................................Y.S.LRlkra.....gdnrsNRNG.IL.L.IYLPDL---------.......-----------fgqynyndgryqaeft.........................................................................................................................................
A0A2P7AER1_9MICO/3-129               ..............................................RKIFISFHQADEIq........anIWI.R.RF.S.Q.YFSE.I.-..-.--.-...-...R....S.L..G..L...H...E...L..G.D....D...F........T.E.H.....I.......ESGDS..E-.....-..--.YVMR.RIrEDKIA..GTS..CTVVLLGQ......C........T......W......A..........R..........R...........Y......V..D..W.E.....I..A......................................................................................................................................................................A.T.LRnf.........tdsQRGG.LI.G.VQLPGTQNLA-MPKL.......PPRL-------alnlaq...................................................................................................................................................
A0A1B1ALW3_9CAUL/7-200               ..............................................YAAFISYSSKDAKf.........aQRL.H.--.-.-.RALE.S.Y..G.IP.S...S...L....G.K..-..F...D...L...I..G.G....G...K........Q.N.R.....Iyp...vfRDREE..L-.....S..AG.HLGD.QI.EANLR..ASA..ALIVVCSP......N........G......A......A..........S..........P...........W......V..Q..K.E.....I..Effaaqgrhakifaiipdtapltdeqgadctqt......................................................................................................cfppafrgdalsgdkleplaadarkgkdgfrnA.W.LK..............IVAG.MV.G.VTPGQIIDRDRKRRR.......QQA--------ltlgsgva.................................................................................................................................................
M7N7G3_9FLAO/93-218                  ..............................................RKTFISYYHKDDQ...........SSK.E.AF.K.N.LTSD.L.-..-.-I.I...N...K....S.V..E..D...-...-...-..-.-....-...-........-.-.-.....-.......GDIDS..DV.....S..DE.YIKQ.LIqKGYLS..DTT..VLVILIGP......N........T......K......C..........R..........K...........H......I..D..W.E.....I..S......................................................................................................................................................................G.A.LNlk.........vgdHFAG.LL.G.LKLPSHPDYGTGKYSys...eqPQRLTDNL---ksg......................................................................................................................................................
A0A343JCU6_9CLOT/4-116               .............................................p-RAFISFDFDHNE...........TEK.T.LF.V.G.QSKN.S.K..T.PF.S...-...-....-.-..-..-...-...-...-..-.I....Q...D........W.S.A.....K.......SSMPQ..S-.....-..--.KWEA.IV.EEKIK..KCN..MVIVLVGK......Y........M......A......S..........A..........T...........G......V..K..K.E.....I..K......................................................................................................................................................................M.A.KN..............NNVP.VF.G.VYVGGANTTS-----.......-----------nlpdglsrtrvvk............................................................................................................................................
#=GC seq_cons                        ..............................................hpsFlSapapsst............hh.p..l.h.p.hhtp...............t......................................t...t........h.p.......l.......ccpsp...............slpp.tl.cpplp..sos..shlVLhu.......p........o......t......p..........s..........p...........W......V..p..h.E.....I..p......................................................................................................................................................................t.u.hc..............hsps.ll.u.lhhtshtp.........................tth......................................................................................................................................................
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