GenomeNet

Database: Pfam
Entry: DUF1933
LinkDB: DUF1933
Original site: DUF1933 
#=GF ID   DUF1933
#=GF AC   PF09147.11
#=GF DE   Domain of unknown function (DUF1933)
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1q15
#=GF GA   20.50 20.50;
#=GF TC   20.50 20.70;
#=GF NC   20.40 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   12890666
#=GF RT   Crystal structure of carbapenam synthetase (CarA). 
#=GF RA   Miller MT, Gerratana B, Stapon A, Townsend CA, Rosenzweig AC; 
#=GF RL   J Biol Chem. 2003;278:40996-41002.
#=GF DR   INTERPRO; IPR015230;
#=GF DR   SCOP; 1q15; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Members of this family are predominantly found in carbapenam
#=GF CC   synthetase, and are composed of two antiparallel six-stranded
#=GF CC   beta-sheets that form a sandwich, flanked on each side by two
#=GF CC   alpha-helices. Their exact function has not, as yet, been
#=GF CC   determined [1].
#=GF SQ   8
#=GS A0A3M7PSN8_BRAPC/41-217  AC A0A3M7PSN8.1
#=GS W0I114_9GAMM/4-196       AC W0I114.1
#=GS H2C3L8_9CREN/18-112      AC H2C3L8.1
#=GS A0A2I5TIM8_SERS3/3-203   AC A0A2I5TIM8.1
#=GS Q2NVG4_SODGM/4-196       AC Q2NVG4.1
#=GS A0A0W0Y099_9GAMM/20-208  AC A0A0W0Y099.1
#=GS F5HGM6_PHOLL/3-201       AC F5HGM6.1
#=GS W0HHL5_9GAMM/4-196       AC W0HHL5.1
A0A3M7PSN8_BRAPC/41-217             .........kkvktisekstlktynfkdlsiclysnrnldklmdyyvhln---------------------..--------------------.---.G..ENSSFLV..GR..VNNEAV....LR.T.KISDY.ENC-...QNLKGAKLISHLVSEYGTSAFNMIEGSYCF.ItI.NH.R.N.G.S.IE.T.Y.S.DSIGLMPTYF.A...NqL..G.S..A..W.I.FNEAK.VF...A.A-.--..-.-.-.------..-----..--..-..-..----....-....-------------------------------nplanlklkpfsdldlgsldhpsdftcfenifkvpkg...............................
W0I114_9GAMM/4-196                  ..................................................NGFCIIHGNINKDISLLAHCCsgNIEMLRNGCLFTGRKTPVQS.YRF.A..TGSAYLI..GS..LRNKRL....LR.H.LATHF.TGGV...PVVNGAEVLYQLSTQLGSAALGLAEGDFCF.F.I.ED.R.N.G.T.LT.L.L.T.DARGQNPVYL.V...N.A..G.D..R..W.I.TDKLK.LI...S.AL.HD..R.-.-.-DIQHD..PQGSE..TA..P..S..VGC-....-....---HIQRILPGTLNVFRFSNADCEVCESRQL....................................................................
H2C3L8_9CREN/18-112                 ...................................allimelldlgvpys---------------------..-----RVSTLFSVSTTTVAK.YRS.K..ARSDVLV..RK..MRDDEQimddIR.I.LARMIrDGGG...SYHHMCELCYLVRKKFFNSVISCRND----.-.-.--.-.-.-.-.--.-.-.-.----------.-...-.-..-.-..-..-.-.-----.--...-.--.--..-.-.-.------..-----..--..-..-..----....-....-------------------------------dds.................................................................
A0A2I5TIM8_SERS3/3-203              ..................................................NGFCVIYKGTDADIDKLQQSFsgKGEVLHSGYLYIGQNTPYHK.FPF.E..KGTAYLI..GT..LYNPDF....LK.T.VAGVW.DGEA...YTANNAALLALLYMRLGEGALAMAEGEFCF.L.I.ED.P.Q.G.E.LT.L.V.T.DSRGFSPVHV.V...E.A..G.K..N..W.V.TNCLK.FV...T.TV.ED..E.N.A.LYFESE..DRVCQ..RS..L..Q..ADDY....T....PIKNAQRLKPGSINVITYDSEGYLFNNC---kal.................................................................
Q2NVG4_SODGM/4-196                  ..................................................NDFCIIHGNINKDISLLAHCCsgNIEMLRNGCLFTGRKTPVQS.YRF.T..TGSAYLI..GS..LRNKRL....LR.H.LATHF.TGGV...PVVNGAEILYQISTQLGSAALGLAEGDFCF.F.I.ED.R.N.G.T.LT.L.L.T.DACGQNPVYL.V...N.A..G.D..R..W.I.TDKLK.LI...S.AL.HD..H.-.-.-DIQHD..PQAGE..TA..V..S..TGC-....-....---HIQRILPGTLNVFRFSNADYQVCESRQL....................................................................
A0A0W0Y099_9GAMM/20-208             .........................eissktlephiiinttswsflfkgq---------------------..-------------SKLPVQN.VLH.ShgSYDYFFI..GE..VYNVAE....LR.V.LLARY.SSNA...LTCAIPELLYLLYAFHGKQAFSLVDGPFT-.F.I.KC.R.D.K.E.LT.V.I.T.DALGCLPVNV.I...F.N..S.S..V..W.V.SSELK.ML...A.KT.KA..V.-.Q.FDFIAP..EQLIA..IE..N..K..SDDF....L....PIKNVRKIKPGQEFSIHWDGQNH--------pyvnavd.............................................................
F5HGM6_PHOLL/3-201                  ..................................................SEFCFVKYGFDKNLNKLINEF..QFDELSTGTILFRSTTKVSK.FKS.E..RYTAFLI..GN..IYNIST....IR.S.ILGKI.EGRS...SVLSDVEILLLSRDKFGNSIISIAEGDYCL.F.I.ED.K.K.G.N.IE.V.I.T.ESRGLNLVNL.V...Q.T..D.L..I..W.I.TNSLK.IV...G.KV.EG..D.K.A.FDFKPE..SEVIK..NS..L..K..PDNF....S....PIRNVSRLKPGTINKLTFDEQRYLHLEVEYV....................................................................
W0HHL5_9GAMM/4-196                  ..................................................NGFCIIHGNINKDISLLAHCCsgNIEMLRNGCLFTGRKTPVQS.YRF.A..TGSAYLI..GS..LRNKRL....LR.H.LATHF.TGGV...PVVNGAEVLYQLSTQLGSAALGLAEGDFCF.F.I.ED.R.N.G.T.LT.L.L.T.DARGQNPVYL.V...N.I..G.D..R..W.I.TDKLK.LI...S.AL.HD..R.-.-.-DIQHD..PQGSE..TT..P..S..VGC-....-....---HIQRILPGTLNVFRFSNADCEVCESRQL....................................................................
#=GC seq_cons                       ..................................................stFChlhhshstslshL.pph..ph-.L+sGsLahsppTPVpp.a+a.s..ssSAaLI..Gs..lpNcch....LR.p.LAs+a.sGss...sslssAElLYhLpsphGsuAlulAEG-FCF.F.I.ED.R.s.G.s.LT.l.l.T.DupG.sPVal.V...p.s..G.s..t..W.I.TscLK.ll...u.sl.cs..c......Dhpt-..sps.p..ps.....p..sss.............plpRlhPGolNshpasstsh.h.ps.......................................................................
//
DBGET integrated database retrieval system