GenomeNet

Database: Pfam
Entry: DUF2016
LinkDB: DUF2016
Original site: DUF2016 
#=GF ID   DUF2016
#=GF AC   PF09436.10
#=GF DE   Domain of unknown function (DUF2016)
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF SE   Iyer L
#=GF GA   24.10 24.10;
#=GF TC   24.20 24.90;
#=GF NC   23.70 24.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   16859499
#=GF RT   The prokaryotic antecedents of the ubiquitin-signaling system
#=GF RT   and the early evolution of ubiquitin-like beta-grasp domains. 
#=GF RA   Iyer LM, Burroughs AM, Aravind L; 
#=GF RL   Genome Biol. 2006;7:R60.
#=GF DR   INTERPRO; IPR018560;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   A predicted alpha+beta domain that is usually fused N-terminal
#=GF CC   to the JAB metallopeptidase. This protein in turn is found in
#=GF CC   conserved gene neighborhoods that include genes encoding the
#=GF CC   bacterial homologs of the ubiquitin modification system such as
#=GF CC   the E1, E2 and Ub proteins [1]. The domain is also known as the
#=GF CC   JAB-N domain.
#=GF SQ   62
#=GS A0A0H3KQT7_BURM1/1-51     AC A0A0H3KQT7.1
#=GS A0A165KY87_9BURK/8-79     AC A0A165KY87.1
#=GS W0SFK5_9PROT/4-75         AC W0SFK5.1
#=GS A0A1M6YPB1_9BURK/53-126   AC A0A1M6YPB1.1
#=GS A1W6B4_ACISJ/8-79         AC A1W6B4.1
#=GS A0A158I1Y5_9BURK/4-76     AC A0A158I1Y5.1
#=GS A0A1G6ZR77_9GAMM/7-73     AC A0A1G6ZR77.1
#=GS A0A0F7JUM1_9SPHN/11-84    AC A0A0F7JUM1.1
#=GS Q120V3_POLSJ/3-73         AC Q120V3.1
#=GS A0A069I9W6_9BURK/4-76     AC A0A069I9W6.1
#=GS A0A158AS77_9BURK/9-81     AC A0A158AS77.1
#=GS A0A1A5XLM5_9BURK/4-76     AC A0A1A5XLM5.1
#=GS A0A1I7M4E7_9BURK/246-317  AC A0A1I7M4E7.1
#=GS F4G940_ALIDK/7-78         AC F4G940.1
#=GS A0A1N6LVG0_9BURK/4-76     AC A0A1N6LVG0.1
#=GS G6EJV6_9SPHN/10-84        AC G6EJV6.1
#=GS A0A0M2LZR3_9SPHN/11-83    AC A0A0M2LZR3.1
#=GS A0A069PJ89_9BURK/4-76     AC A0A069PJ89.1
#=GS A0A1Q3VUU0_9PROT/8-78     AC A0A1Q3VUU0.1
#=GS A0A069NS28_9BURK/4-76     AC A0A069NS28.1
#=GS Q21Q53_RHOFT/9-78         AC Q21Q53.1
#=GS A0A1D9HCL7_9BURK/4-76     AC A0A1D9HCL7.1
#=GS A0R7L0_PELPD/5-76         AC A0R7L0.1
#=GS A0A0K9K0K3_9BURK/9-81     AC A0A0K9K0K3.1
#=GS Q7WX35_CUPNH/4-76         AC Q7WX35.1
#=GS A0A258NQ90_9BURK/4-74     AC A0A258NQ90.1
#=GS Q11ZD2_POLSJ/1-71         AC Q11ZD2.1
#=GS A0A1H4DU27_9BURK/3-74     AC A0A1H4DU27.1
#=GS A0A1Q8IKJ1_9BURK/4-76     AC A0A1Q8IKJ1.1
#=GS A0A0F5PH19_9SPHN/10-84    AC A0A0F5PH19.1
#=GS A0A0Q6W4E1_9BURK/5-76     AC A0A0Q6W4E1.1
#=GS C5T055_ACIDE/7-78         AC C5T055.1
#=GS A0A139BN16_9PROT/4-75     AC A0A139BN16.1
#=GS A1VVA1_POLNA/3-75         AC A1VVA1.1
#=GS B1T0G3_9BURK/4-76         AC B1T0G3.1
#=GS A0A158E4V9_9BURK/9-81     AC A0A158E4V9.1
#=GS A0A1G6W027_9BURK/4-76     AC A0A1G6W027.1
#=GS A0A1G0EQ03_9PROT/4-75     AC A0A1G0EQ03.1
#=GS Q1L9T1_CUPMC/4-76         AC Q1L9T1.1
#=GS D9SEQ3_GALCS/4-75         AC D9SEQ3.1
#=GS A4JUM8_BURVG/4-76         AC A4JUM8.1
#=GS Q5NXB5_AROAE/4-75         AC Q5NXB5.1
#=GS B2UDC7_RALPJ/4-76         AC B2UDC7.1
#=GS A0A1E4QXH3_9BURK/4-76     AC A0A1E4QXH3.1
#=GS A0A246J8N1_9BURK/6-77     AC A0A246J8N1.1
#=GS A0A1M6RVI4_9BURK/53-126   AC A0A1M6RVI4.1
#=GS A0A1E3LXB5_9SPHN/11-83    AC A0A1E3LXB5.1
#=GS Q47D11_DECAR/5-75         AC Q47D11.1
#=GS F4GGG6_ALIDK/8-79         AC F4GGG6.1
#=GS A0A172UG16_9GAMM/11-82    AC A0A172UG16.1
#=GS A0A1B3ZI78_9SPHN/13-85    AC A0A1B3ZI78.1
#=GS N6Y9C8_9RHOO/4-75         AC N6Y9C8.1
#=GS A0A1F4JY84_9BURK/1-71     AC A0A1F4JY84.1
#=GS Q8XYU8_RALSO/53-126       AC Q8XYU8.1
#=GS W7WVK0_9BURK/6-77         AC W7WVK0.1
#=GS A0A158HXE5_9BURK/4-76     AC A0A158HXE5.1
#=GS A0A0Q4XRM1_9BURK/5-75     AC A0A0Q4XRM1.1
#=GS A0A158DK61_9BURK/4-76     AC A0A158DK61.1
#=GS A0A259ENU6_9PROT/5-77     AC A0A259ENU6.1
#=GS A0A1D9HD39_9BURK/4-76     AC A0A1D9HD39.1
#=GS A0A0L0M4C1_9BURK/9-81     AC A0A0L0M4C1.1
#=GS F2LSQ3_BURGS/4-76         AC F2LSQ3.1
A0A0H3KQT7_BURM1/1-51                .........................-------------------...---MT..RSGERLLITSDGVYLEVLRPWVRVVRRIA.hYAVSTAVPYGQVEETTAF-s......
A0A165KY87_9BURK/8-79                .........................RDQALLAACPVVAAPRFGA...LPDMA..-NGQRIVVARNGWFVQTRLDWLDSITALG.lEPPAMRLPYGEVQECLRF-s......
W0SFK5_9PROT/4-75                    .........................RDIALQHSAPVVTVPRYGG...FTPLV..ENGHRFLVTGDGLWLEARRPWLYLRVPLV..CQKSVPMPYGWVGRELSL-s......
A0A1M6YPB1_9BURK/53-126              .........................LDAALFDSAPTVAVPKHAK...FAPLA..DVGHRFLMTAQGVFIEVRRPWLHVIQQLAkhNDTGPRPPYGDIEPKIEL-a......
A1W6B4_ACISJ/8-79                    .........................RDQALLATCPVIAAPRFGT...LPDMG..-NGQRIIVARNGWFVQTRLDWLDSIVALG.qGLPPMRLPYGEVAEHLRF-s......
A0A158I1Y5_9BURK/4-76                .........................ADSVLQRSFPTVMVPRREP...VGPMA..SAGERLLVAENGVFLEISLPWISLVRRVA.sFTAPVPLPYGSVAEHTNL-i......
A0A1G6ZR77_9GAMM/7-73                ..................ldatlfp---------PLVPAPRFGS...LSQLQ..PGQKRFLGACDGLYVEARSAAMRLRLKVA..---NAVLPFGPLAAQVEL-d......
A0A0F7JUM1_9SPHN/11-84               aailaaapcypvppigrspaidavr-------------------...---AS..RTGHCLAVGRDGVMLIVRRPWLELDIPVT..PAFPAYLPYGSVGER----rae....
Q120V3_POLSJ/3-73                    .........................LDSIIQGMFPTVIMPREGT...IAPAT..KNGTRYVVAGDGLWREVVLPWVTVMHKIA..-NSDFMLPYGAAEEAVVI-k......
A0A069I9W6_9BURK/4-76                ........................a-DVTLQQSFPSIMVPRLST...LEPMT..RAGERLLIAANGVFLEITRPWLKVVRRLG.gFQHRTTIPYGNASEETDL-l......
A0A158AS77_9BURK/9-81                .........................ADAALQRSFPTVMVPRRES...VAPMQ..AAGERLLIGENGVFLEIDLPWLSVVRRIA.hYTVPTAIPYGKVVESTEL-r......
A0A1A5XLM5_9BURK/4-76                .........................LDVALQGSFPSVMVPTREP...VAPMG..GPGERLLIASNGVFLEISRPWVRLVRRLS.sFDWRTPVPYGAAAEHTDLK.......
A0A1I7M4E7_9BURK/246-317             .........................RDAALHAALPIVAAPRHSE...LPPMA..-TGLRLVVAANGVFTQVRLPWLDCLQRCG.gIDTGLPLPYGTFAPWLR--ls.....
F4G940_ALIDK/7-78                    .........................RDQALLAACPVIAAPRFGA...LPDMG..-NGQRIIVARNGWFVQTRLDWLDSIVALG.hGSPSMRLPYGEVAEHLCF-s......
A0A1N6LVG0_9BURK/4-76                ........................v-DFVLQRSFPSVMVPAREP...LAAMA..GPGERLLVAADGVYLELARSWIHVVRRIA.rYEVDTAIPYGAVEQKTEL-l......
G6EJV6_9SPHN/10-84                   ......................aaa----LIAAAPCYPVPSTGRspaLDALRdgRAGHGLAVGKDGVMLILRRPWLALDAPLS..PPFAAHIPYGSIGE-----pkad...
A0A0M2LZR3_9SPHN/11-83               aallaavpcfpappsgsspgldavr-------------------...---AS..RAGHCLAIGRDGVFLIVRRPWLELDVPVT..PPIAAYLPYGSVGE-----pra....
A0A069PJ89_9BURK/4-76                ........................g-DMALQRSFPTVMMPRREP...VAPML..AAGERLLIGENGVFIEIDLPWLSVVRRIA.aYTVPTAIPYGKVVESTVL-r......
A0A1Q3VUU0_9PROT/8-78                .........................LDEVLQQVCPTVMVPRYEP...LQDLD..HEAHRFLVAQDGLYMDVLRPWLQLRLQIS..-QSPIPLPYGRVAGKA---vfn....
A0A069NS28_9BURK/4-76                .........................ADAALQRSFPTVMVPRREP...VAPMQ..AAGERLLIGENGVFLEIDLPWLSVVRRIA.hYTVPTAIPYGNVAESTEL-r......
Q21Q53_RHOFT/9-78                    .........................IDRFLATDCPVITMPHDSE..vFEPLK..TPGHRLIVAAGGLYKEIRRAWLHAIVHVA..---RAQTPFGELQTTLSM-p......
A0A1D9HCL7_9BURK/4-76                .........................RDMTLQASFPTIEMPRFEP...LPPLA..RPGERLVVGSNGLFLEISRPWIHLVRRIA.aFNVPTAIPYGAVVAATDF-r......
A0R7L0_PELPD/5-76                    .........................MDAILQEQFPTVMVPRYGD...FVPLA..HNGRRFLSASDGLWLEEKNQWLHILWPLA..LQNQVAMPYGSLQKKVDF-l......
A0A0K9K0K3_9BURK/9-81                ........................g-DAALQRSFPSVMVPRREP...VTPMQ..TCDERLLIGENGVFIEIDLPWLSVVRRIA.hHTVPTAIPYGKVIESTVL-r......
Q7WX35_CUPNH/4-76                    .........................ADAALQQSFPSVMVPRFGA...LAPME..RSGERLLIAANGVFLEIVRPWLSVVRHLG.aFQHRTAIPYGEAAETTDL-r......
A0A258NQ90_9BURK/4-74                .........................MDQVVQAAFPVVSAPRFSS...LEAGA..KPGSRHIVAKDGLWREITLPWIRSIHPIA..-ACDVPLPYGALHAEIEL-f......
Q11ZD2_POLSJ/1-71                    .........................MDAIIQSQFPTVLAPRFEA...LSPLE..TTGDRFILTRHQVLMEVSRPWLHAIQAIS..APFARQTPYG-A-------gprlgik
A0A1H4DU27_9BURK/3-74                .......................ie--QVLRDQFPVIHAARSVP...HQPLA..ETGVRYVVSSQGLWRELSTAWLYALLPLA..KAPSAMIPFGSLESTVEFR.......
A0A1Q8IKJ1_9BURK/4-76                .........................LDMTLQRSFPTVMVPRNEA...VAEMQ..TAGERLLVAENGVFLELRRPWLSLVRQIA.eFTVPTAIPYGRVTPATRL-l......
A0A0F5PH19_9SPHN/10-84               ......................aaa----LIAAAPCYPVPSTGRspaLDALRdgRAGHGLAVGKDGVMLILRRPWLALDAPLS..PPFAAHIPYGSIGE-----pkad...
A0A0Q6W4E1_9BURK/5-76                .........................RDAALQAACPVIAAPRHGD...LPPMV..-PGLRIVAAANGLFVQVRLPWLDCLQRCG.sVDLGLPLPYGTLAPWLRL-s......
C5T055_ACIDE/7-78                    .........................RDQALLAACPVIAAPRFGA...LPDMG..-NGQRVIVARNGWFVQTRLDWLDCIVALG.hGQPLMHLPYGEVAEHLRF-s......
A0A139BN16_9PROT/4-75                .........................RDVALQSVMSTVMVPHFSE...LVELD..TPGNRILMASNGIWLEVCRAWFYARVPIA..KPLSMATPYGMVSEVLRF-g......
A1VVA1_POLNA/3-75                    .........................LDQITMGVFPLLAASQTGV...LQDPE..KHGVRYVAASDGMWRAIDTAWLKALTPVA.lSSKKAVIPYGRLTQSVEF-l......
B1T0G3_9BURK/4-76                    .........................LDTVLQQSFPSVMVPSREA...VVPMA..RSGERLLIASDGVYLEISRPWVHVVRRIA.qYAVSTAVPYGNVEETTEL-l......
A0A158E4V9_9BURK/9-81                .........................ADAALQRSFPTVMVPRREP...VAPMQ..AAGERLLMGENGVFLEIDLPWLSVVRRIA.hYTVPTAIPYGKVAESTEL-r......
A0A1G6W027_9BURK/4-76                .........................ADAALQQSFPSVMVPRFGA...LPPLE..RPGERLLIAANGVFLEIVRPWLRVVRRLG.aFQYRTAIPYGEVEEATEM-r......
A0A1G0EQ03_9PROT/4-75                .........................RDVALQSVMPTVMVPRYAE...LEELD..TPGNLILMASNGVWLEVCRAWLYARVLVA..HPLRIPVPYGMIHEELRF-g......
Q1L9T1_CUPMC/4-76                    .........................ADMALQQSFPSVMVPRHGA...LPALE..QVGERLLIAANGVFLEIVRPWLRVVRRLG.eFQHQTAIPYGDATEVTEL-r......
D9SEQ3_GALCS/4-75                    .........................RDVALQSVMPTVMVPRYAE...LEELD..TPGNRILMAENGVWLEVCHAWLYARIPVS..LPLRIPVPYGVIYEELRF-g......
A4JUM8_BURVG/4-76                    .........................LDTVLQQSFPAVMVPSRET...VVPMT..RSGERLLIASDGVYLEVLRPWVRVVRRIA.qYAVSIAVPYGKVEETTAL-l......
Q5NXB5_AROAE/4-75                    .........................RDMALQALTPTVMVPRFGC...FEPLS..QPGHRFLVGQNGEWLEVRRAWMYARVQLT..QPSPVVKPYGVVTACLEW-l......
B2UDC7_RALPJ/4-76                    .........................MDMTLQASFPTIMVPKFGS...LTPLS..GSGERLLVGTNGVFLEVVRPWLRVVRKIA.sYEVETAVPYGTVNEETEL-p......
A0A1E4QXH3_9BURK/4-76                ........................a-DVTLQQSFPSVMVPRFSR...LEPMP..RAGERLLIAANGVFLEIARPWLRVVRRLG.pFQHRTAIPYGDASEETDL-t......
A0A246J8N1_9BURK/6-77                .........................RDLALQATCPCVPVPRFGA...LPDLD..-LGQRVLVARNGLFLDVRRSWLRCVTRLA.dLPPTPPLPYGVLRERIEF-a......
A0A1M6RVI4_9BURK/53-126              .........................LDAALFDSAPTVAVPKHAK...FAPLT..DVGHRFLMTAQGVFIEVRRPWLHVIQQLAkhNDAGPRPPYGDVEPTIEL-a......
A0A1E3LXB5_9SPHN/11-83               aallaavpcfpappsgsspgldavr-------------------...---AS..RAGHCLAIGRDGVFLIVRRPWLELDVPVT..PPIAAYLPYGSVGE-----pra....
Q47D11_DECAR/5-75                    .........................RDLALQAVCPVIAAPRFGP...LPDMA..-NGQRIILAANGVFVQVKLDWLDCIQRLS..PALPITLPYGGIEERLAF-t......
F4GGG6_ALIDK/8-79                    .........................RDQALLAACPVVAAPRFGA...LPDMA..-NGQRIVVARNGWFVQTRLDWLDSITALG.lEPPAMRLPYGEVEERLRF-s......
A0A172UG16_9GAMM/11-82               .........................RDRILFGETPTYMQPLFGE..kLPAPE..LGKHRFVIGQEGVVLEAINEVFEVRLPVA..-QSIIKLPYGVLG------aqgvrl.
A0A1B3ZI78_9SPHN/13-85               .ailaaapcypvppsggspaidavr-------------------...---AS..RTGHCLAVGRDGVSLIVRRPWLELDVPVT..PPIPAYLPYGSIGER----ran....
N6Y9C8_9RHOO/4-75                    .........................RDAILQQVTPTVMVPLYGA...FEPLG..KLGHRFLSAGNGEWLEVRRSWLYARTRNL..SPGAVAKPYGQVTGTIEW-l......
A0A1F4JY84_9BURK/1-71                .........................MDKAVQAAFPVVSAPRFSS...LEAAA..KPGARHIVAKDGLWREVTLPWIRSIHLVA..-ACDVPLPYGALHAELEL-l......
Q8XYU8_RALSO/53-126                  .........................LDAKLWDSAPTVAVPKFAE...FKQLE..DVGHRFLATAEGLFVEVRRPWLHVIQPVAplNGQTVRPPYGTVKQKVDL-a......
W7WVK0_9BURK/6-77                    .........................MDGVLLDMFPVVAVPPSGQ...LAKPS..RDGQRYLVGNSGLFREVSTPWLYAVYPIA..SISGLATPFGEVKTTVTI-g......
A0A158HXE5_9BURK/4-76                ........................a-DLALQRSFPTVMVPRREP...AEPMQ..AFGERLLIAQNGVFLEINQPWLSLVRRIA.aYSVATAIPYGEVAESTRL-m......
A0A0Q4XRM1_9BURK/5-75                .........................RDLALQASCPVLAAPRFGP...LPDMV..-NGQRVIVAANGVFVQVRLDWLDCVQRLA..PPLGVPLPFGALQERLQF-s......
A0A158DK61_9BURK/4-76                ........................g-DLALQRSFPTVMVPRREP...VAPMA..AAGERLLIGENGVYIEIDLPWLSVVRRVA.hYSVPTAIPYGQVVESTVL-r......
A0A259ENU6_9PROT/5-77                .........................RDVALARSFPIIAVPRFGI...FKPLS..TNGQRLLVTANGFFLEVRRDWLYAVQPCG.iPLGIVRYPFGDVATSIQL-a......
A0A1D9HD39_9BURK/4-76                .........................MDATLQASMPTVMVPRFGA...LVPMP..SAGERLLMAANGVFLEVCRPWVRLVRRIA.sFSVPTAIPYGVVEEATDL-l......
A0A0L0M4C1_9BURK/9-81                ........................g-DAALQRSFPSVMVPRREP...VAPML..AAGERLLIGENGVFIEINLPWLSVVRRIA.hYTVPTAIPYGRVVESTVL-r......
F2LSQ3_BURGS/4-76                    .........................IDTVLQMSFPTVMVPRREP...VHSME..RPGERLLIAANGVFLEVLRPWVRVVRRIA.mYHEKTPIPYGAVDEVTEL-r......
#=GC seq_cons                        .........................hDhsLQtuhPsVhsPRhus...lsshs..psGcRlLlupsGValElppPWLcllptlu...shssslPYGpltEphch.t......
//
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