GenomeNet

Database: Pfam
Entry: DUF2067
LinkDB: DUF2067
Original site: DUF2067 
#=GF ID   DUF2067
#=GF AC   PF09840.9
#=GF DE   Uncharacterized protein conserved in archaea (DUF2067)
#=GF AU   COGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   COGs (COG3286)
#=GF GA   24.90 24.90;
#=GF TC   24.90 24.90;
#=GF NC   24.50 24.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR019202;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This domain, found in various archaeal proteins, has no known
#=GF CC   function.
#=GF SQ   59
#=GS Q8U4N0_PYRFU/9-196       AC Q8U4N0.1
#=GS A0A0P0N129_9CREN/11-197  AC A0A0P0N129.1
#=GS A0A2E9CF97_9ARCH/16-204  AC A0A2E9CF97.1
#=GS A0A150JGT9_9EURY/11-188  AC A0A150JGT9.1
#=GS D9Q2R3_ACIS3/9-193       AC D9Q2R3.1
#=GS A0A256Z8W4_9CREN/8-197   AC A0A256Z8W4.1
#=GS A0A150IJ51_9EURY/2-140   AC A0A150IJ51.1
#=GS A6UTG3_META3/7-198       AC A6UTG3.1
#=GS A2BNA2_HYPBU/12-198      AC A2BNA2.1
#=GS D5VRW0_METIM/8-192       AC D5VRW0.1
#=GS A0A133VAA8_9EURY/10-69   AC A0A133VAA8.1
#=GS L0AAH3_CALLD/10-195      AC L0AAH3.1
#=GS Q9YEZ0_AERPE/14-201      AC Q9YEZ0.2
#=GS B1L7Q6_KORCO/4-167       AC B1L7Q6.1
#=GS A0A256YMF6_9CREN/12-195  AC A0A256YMF6.1
#=GS A1RXJ8_THEPD/8-193       AC A1RXJ8.1
#=GS Q5JE87_THEKO/9-196       AC Q5JE87.1
#=GS A0A1Q9N3Y7_9ARCH/25-205  AC A0A1Q9N3Y7.1
#=GS G4RLB4_THETK/7-189       AC G4RLB4.1
#=GS I0A280_FERFK/13-201      AC I0A280.1
#=GS F6BDC1_METIK/7-191       AC F6BDC1.1
#=GS A0A218P4C0_THECE/10-197  AC A0A218P4C0.1
#=GS Q8ZW47_PYRAE/7-188       AC Q8ZW47.1
#=GS A0A0U3EDA1_9CREN/8-192   AC A0A0U3EDA1.1
#=GS A8AA06_IGNH4/8-191       AC A8AA06.1
#=GS B8D6L0_DESA1/11-194      AC B8D6L0.1
#=GS A0A1Q9PFV0_9ARCH/14-200  AC A0A1Q9PFV0.1
#=GS G0EET6_PYRF1/10-197      AC G0EET6.1
#=GS D7DR79_METV3/8-197       AC D7DR79.1
#=GS A0A150IYC8_9EURY/10-188  AC A0A150IYC8.1
#=GS A8MB33_CALMQ/11-198      AC A8MB33.1
#=GS C6A1R4_THESM/9-196       AC C6A1R4.1
#=GS A0A256ZWX9_9CREN/24-213  AC A0A256ZWX9.1
#=GS G0HN60_THES4/10-197      AC G0HN60.1
#=GS Y388_METJA/7-191         AC Q57833.1
#=GS F2L3J3_THEU7/7-189       AC F2L3J3.1
#=GS E0SNR9_IGNAA/16-198      AC E0SNR9.1
#=GS A4WMI1_PYRAR/7-188       AC A4WMI1.1
#=GS A0A218P7S0_9EURY/10-197  AC A0A218P7S0.1
#=GS A0A0V8RUH5_PYROC/11-197  AC A0A0V8RUH5.1
#=GS A0A0F7FI31_9CREN/8-193   AC A0A0F7FI31.1
#=GS A0A1Z2TL77_9EURY/10-197  AC A0A1Z2TL77.1
#=GS B6YTH6_THEON/10-197      AC B6YTH6.1
#=GS A0A150IXF5_9EURY/11-189  AC A0A150IXF5.1
#=GS S5ZDK7_9CREN/8-193       AC S5ZDK7.1
#=GS Q6M0K8_METMP/7-198       AC Q6M0K8.1
#=GS C5A5J4_THEGJ/9-198       AC C5A5J4.1
#=GS A0A075M066_9EURY/10-197  AC A0A075M066.1
#=GS Q8TZ80_METKA/11-198      AC Q8TZ80.1
#=GS A0A256XV84_9CREN/7-163   AC A0A256XV84.1
#=GS A0A160VRE6_9EURY/9-196   AC A0A160VRE6.1
#=GS I3TDP1_THEC1/8-194       AC I3TDP1.1
#=GS D5TZM0_THEAM/10-196      AC D5TZM0.1
#=GS W0I759_9EURY/9-196       AC W0I759.1
#=GS F8AIG5_PYRYC/9-196       AC F8AIG5.1
#=GS A3DM81_STAMF/12-199      AC A3DM81.1
#=GS E1QTA2_VULDI/11-204      AC E1QTA2.1
#=GS A0A100XX70_9EURY/10-197  AC A0A100XX70.1
#=GS O57821_PYRHO/9-196       AC O57821.1
Q8U4N0_PYRFU/9-196                  .............l-HVRDDIEKEE.FMKEVQR.lNLSAFIYIHGKLD--....SLKVNVQGTKEEI........REAIRAIRDAHKRv..rgRLYPDRKGLYT.YYPEDIFREAN..ANISLPILIKTLEL.LGERVEVK-.EDYIKSSMPWREIVELVRRLNEVLS.QI.ALQT-.TRQIREVVAPVSVAYKI.DPE..ELLDLLVDLGI....AEykEDKFKYELVKNKEQALK................
A0A0P0N129_9CREN/11-197             .............a-NLPPGIPIDK.VYEKISS..AI-RSGYAEISIRGG....RVYIEIVGTEFEI........KDSWYRVRQALADl...wELYRLR-TRRE.ASIEAIVKEAG..RTFPPEALVYALEL.RGYEARLSDdKSLLYTTAPPEEVITTARKIADAID.QL.KYRVR.GSAAKRMIAAIAAGLDV.DVE..HVIEYGLRSRV....LE..ETEDGIILREEWRRGL-r...............
A0A2E9CF97_9ARCH/16-204             ...........isf---SPNNPIERdLFLDLSA..KIIKDANAVYDTSHN....KIEITLRGQKEEI........SSLISSINNIQNQi..ilANRPDKNNYYT.FNEKILSQLFN..PPLSFDLYSSCLEX.LGFITKFS-.NAKLTTDANITDLKNIHPQILNYKS.QL.SRKF-.NKDIEKFLISMSLLSKTnNIE..NIIDISIQSNI....IK..KTDYDYQFTMSIELA--sk..............
A0A150JGT9_9EURY/11-188             .....kikgnqkve-----------.IAHFLS-..---KFEXIVFNISDD....TXKIKVLNS-GXM........GEIIYSIKSFLEEl..keSEVKEEKGMXS.YTLXXISKIAG..VTVPVKLLKVVLXD.YGYSFEVN-.RENVVSTASVSIAAEXAGYISYLLX.DL.KD--V.SKPVTEXIVRVAMEYDL.LSS..ELLSVGIEDKI....F-..NDTDTVSLNISYDEAL-l...............
D9Q2R3_ACIS3/9-193                  .........iklpr----NTADIEA.LLEKISE..KA-SASIISTEIRNN....RLVIEIQGSVRAS........KDIKRTVHDILRD.....---QTSRSFRS.VITEDRIRDMG..YKGPMDVLSFTLKK.MGFDTEWE-.PPVLRSNAQVSVIRQVAQKLSDALK.LV.SGLNL.SESARKAVMAVLALSGA.STDveRVISVGLSKGV....LA.rDRNNKILSVTEWREA--ad..............
A0A256Z8W4_9CREN/8-197              ..........lkce----GRDECLE.LVEYIMNyrGV-KAKSLIYEVGNE....SVIIEINGPRIEV........VTTKRVIMKAYREw...mKIKAWSRGSGS.IEIQTLMRIVG..KPFVGDALVEVLKH.LGYEAEIK-.RGTLISNAPSDIVIDVAKALSQKLE.ELvTYKPRaSITAKALITAYAYLTSM.NAK..NALKVLEESGA....LR..INGHRVLVTKEWRSLL-r...............
A0A150IJ51_9EURY/2-140              ...........gdl-----------.-------..---------------....-------------........---VYSIKSFLEEi..keKEIKEEKGIFT.YNLDSISKIAG..ITVPVKLIKAVLID.KGYSFEVD-.KENVVSSAHISVAAEVAGEISYLLE.DL.EG--V.SKPVTEIIVRVAIEFDM.LSS..ELLNVGIDEKI....F-..NDSETVSLNISYDDAL-s...............
A6UTG3_META3/7-198                  ............ik---ATNDEIEE.ICDAISK.mDIDCSIESKVSYSKDeiinILRIKVYGHDKIQmm...qdyKNIMNLADRIHKK.....-YKPNKIGLFE.YQLNDVK----..YPVNKELLKEAIGA.LDIEYKYDEeKNIIKCSLPLEELHDMTKELYGIYK.EL.DFTNVgPKPVKNIITVISYITKK.DIY..DIIDESIEQEF....LR..EENDKIVLNKDIKLIK-e...............
A2BNA2_HYPBU/12-198                 ..............INLPPGIPLEK.IYEKVSS..AF-KAGYAEISIQGN....KLFLEVVGTEYEI........KDTWYRVRQAVSEl...wELYRLSK-GME.ASIEALVREVG..RTFPPESLVYALRL.RGYKAELSDdKSRITTNAPLDVVVEVARTIAEVID.EL.RFRVK.GTAAKRMIAALAA----.GLQ..EPAEKVIEYGLrsrvLE..ETEEGIELREEWRRGL-r...............
D5VRW0_METIM/8-192                  ..............FRVKRDEEILE.LCRALEK.mGLNCTVES--K--DR....RVKVSIYGYDKESlk...enyRNVMSLIYKIKNK.....-YNPDKRGLYK.YYLSELK----..YPVNKELVMETLKA.LGYKVIYNEdESYIKTDVDIDTFNSILENLFNISN.EL.RFSRLgSKPVKNLVVLVSYINGV.PPE..DVIEEALEKGF....FR..VEEGRIVLNKSIELAKK................
A0A133VAA8_9EURY/10-69              ..............FHIDDSEHLIE.IMEGLSN.lNVDLEADS----TPS....SVKVTIYGSREKI........KNTSKKIRSLVEE.....-----------.-----------..--------------.---------.-------------------------.--.-----.-----------------.---..-----------....--..-----------------akss............
L0AAH3_CALLD/10-195                 ..............FNLKEGYDIEN.IFKKINT..VI-SSQEATIKVENN....KLIIDFYVTPRDI........NYIKSKIKEILSF.....ETNKNKVKGFK.YSLKDLNPEGG..-KDFFDMLEFCLSK.LGYKTTIQ-.EEFLITTARKEKVYSLANIINENLK.HI.SGKNY.GNALIKALACYLTLRER.DFE..K-INNVIEKGLslgiLE..ENKNKIYTRYSWKDTY-e...............
Q9YEZ0_AERPE/14-201                 .............l-RLLDVDDFER.FLERLSR..AV-KVDYSSWRREGD....KLLIEMVGGESSI........RESIVRVKALLRE....yRRRARGGGLFS.YSLRRVSREAG..VAVPPDVLSTVLSG.MGYRVEARSgEGVLDTDAPWSLVVEVAREVGERLR.EA.AAQPL.TTSSRKLVVAASILAGS.TLD..DAVRAAVEEGL....LE.eDEKGRLLVRGGWRESLK................
B1L7Q6_KORCO/4-167                  ...........rdy-----------.-------..--------SYKYSVD...sGLKITLFGDKEEL........RDSEAIVRRSYRNf..riV-RNPVGGLYR.YPSDWLS-EHG..-GISMSLLTLSLRA.AGLTAIWK-.EDILHTALEPEEIIDLMLELKSLSE.EI.RYEVR.QRKAREVIVAVSVNSGV.SPF..DVLELAEEEGF....ME.kDDEGLWRFKADPE----lvmr............
A0A256YMF6_9CREN/12-195             ............ck-----SSECIK.IAEIIRE..KAPAVGSMDLEIRDN....GIYITMYGYKTDI........KNAWEYIRRMIIAy...kQSIIEYKGYRR.ISIDYLVSKIK..HTFPPKLLVEIIKH.MGHSIDID-.DHIIVTNAPLEIIEDTAKRIVELMD.TI.KYDVR.GKTTKYYVITLSILTNK.DPS..EIYEKGLMLNH....LI.kDEDDKYRIRVEWRKA--i...............
A1RXJ8_THEPD/8-193                  ..............FTFNDSGEAVS.FLSMLKK..EL-----------GD...aRLYGEIKGKKLKVfipegertDDIVRRVKTLYRE....iHEKTLTVRPRK.LGVSTILSMANleVAIPVPALADVLNM.VGKKAVLR-.GEYLETNASLKEAVEFAEKLSRAYK.SL.LHEPL.TATARRLAAVASVVLGT.EPD..KAVDLLVSKGI....LK..QVEGNVSLSEEYTKSL-s...............
Q5JE87_THEKO/9-196                  ..............IHVRDDREKEE.FMRELQR.lRLPAFIYVHGKLD--....SLKINVQGTKDEI........REAIQKIREIHTRv..raKLYPDRMGLYR.YKVDDLLREAG..TSVSTPIIVKTLEL.LGERVELK-.DDEIVTSMPWEEAVEVTSRLGEALA.EI.ALQT-.TRQIREVVLPVAIAYDL.DPE..EVLERLVELGL....AEwkEDKFKYELVKNKEQALE................
A0A1Q9N3Y7_9ARCH/25-205             vkleelldiyldvi-----------.-------..---GNSDAEIDMKID....KISISLIGDRSNN........DMIASKLQELQGQl..mkATTPDANGNYF.YE-QELFPLIF.nNPIQTRFLADILAV.FKYTSELTE.DKTIITNASLYDVQRLQKIGYSSLN.QS.PKDQ-.NKDIQRFALLNSLKLSK.SPE..EILQLGIANGL....LF..EKEGKIHFSNTREKT--qe..............
G4RLB4_THETK/7-189                  ..............VKFASKEELEH.FLELLPV..YVKTEYYA--IVRGN....NVYIQLSGSPADI........KRSAAVVKTAAGI.....-ARTKIRPLRS.YPLDMVFAKAEvvAPVPPDVLADYLEA.SGHRAKLR-.GLDLQTDATFEEVTRALERLSAVYK.TL.EKYPV.SPHAKRVVALYIAVKRV.SPE..EALERLTSIGI....L-..NKGDVYSIRGNLAAAKK................
I0A280_FERFK/13-201                 .............l-RIPKNADVER.FLDAIMG.sTI--ATQVMYRIKGN....SVEIRIIGDPVSV........ENSIHRIRSAVEDfaikmGYPKEGRGITV.FG-SMLAKSLE..VPVPLEGFKRLLEL.ENIDFSYDEkEDLLVIYDDLEELKSLAKDLFDSYK.SA.REIAR.-GIGAEIIAVLSVYSGL.SPM..EIASIGEEEGV....FE..KIEDMYMLKADKDKALN................
F6BDC1_METIK/7-191                  ...........akt---SCSEEMLE.ICDRISK.lNIDCLIES----REN....LLRIKIFGYDKDSiv...enyRTIVSIIERVHRK.....-YTKDEEGMYE.YSLSDLK----..YPVNKDLIIDTLKA.LGHNVKYLKeEGVIKTSLELDKLNEILCELNEIYG.EL.AFRNIgSKPVKNVIVLAAYLTGK.DVD..EVIEEGLEKEF....FR..EENGRIVLNKDIKLAKK................
A0A218P4C0_THECE/10-197             ..............IHVHDEREKEE.LLREIGR.lRLPAFIYVHAKLN--....GLKINVQGTKDDI........REAIGRIREIHNRv..raKLYPDKRGLYR.YRIDDLLREAG..TGVPTPILVKTLEL.LGERVELR-.EGELVTSMPWEELVSLAKRLGGYLS.DV.SLQT-.TRQIREVVLPVAALKGL.DPS..EVIDLLVELGL....AEwkEDKFKYELVKNKEQAM-k...............
Q8ZW47_PYRAE/7-188                  ..............FKFNSREEMER.FLEFLEK..HVKTTYLVTTRLT--....HVYVQLEGEGKEL........EDAASLVKKLAGL.....--ARQQRHTVQ.IPLVVLFRDADlaRPVPPDVIADALKL.KGMPSEVR-.GGVLETAASYEEVLKTAEALSKIYE.ET.ERLPL.TPQAKKIVVAYAFARGM.PVD..KAAEELAATGL....L-..NVGSVISLRNTLEETR-r...............
A0A0U3EDA1_9CREN/8-192              .............v-KCRSNESCLE.LLNKITE..NV-SSRFLKSEIKGN....TLQLEVIGLPYEL........KEIKYDIEMLKKE.....IESKHIKGNKY.IKLHELGKLFH..GTISIEVLSTVLKS.RGYYVEVD-.DDKLYTNAPMDIIEEIVKKSKEIQEdEV.VKYKL.SSAAKRVVITLSLITDT.PPN..EVIELLKSQGF....LE..QGSFRYQLKENANAV--in..............
A8AA06_IGNH4/8-191                  ...........ikc---INEEVCYE.LLHKISE..EV-SARWIKGEVDGN....KLLIEALGFPYEL........KELRYEIEELKKE.....-IESAMLPYTR.VSVDELPKLTK..AAVPIDALVEALKL.LGYSAKVE-.GRTLVSDAPFEEVAALARKMKEIID.SE.IVRFRlPHSMKKAVAVLSTVYGV.NPE..EVVNVMLREGL....LE..EGDFKYEQREEWRKVIK................
B8D6L0_DESA1/11-194                 ...........pcr-----GEECLK.LYELVKE..RVPSIEHVEFAVTSN....GLIVDAYGYETDL........KKLWIELKNYSRM.....AKGVSGPGLQA.FSIDVIVKLTR..KTFPPEVLVKILEK.QGYKARLE-.DGTIYTNIEKNRILELVERISELNT.AI.RGRVK.GTAARYFIITVTIITGL.QLD..DAINHAVEAGL....LG.vDESGLYVLKHEWRDA--vd..............
A0A1Q9PFV0_9ARCH/14-200             ..........vsiv----KKELLEY.FLELLSD..SLRYVEFV-FTYRKG....KSKVSLFGERETI........NQSALIVKSLAKMf..nqSSILNSDGFYV.HNLKLIQ-QIG.sKIISLQSISTVLNH.LDVQSTVK-.DQDLVSKASMQEVQKILSSMHDLIQ.ET.PLGVR.TQVMKRILATVSYCTNL.SPS..FVLDKGLELEY....FK..QQKNTISINYNPEKSI-r...............
G0EET6_PYRF1/10-197                 ..............IRVPPGIDLDK.LNERLRE..AI-RVPYAEIEVEKD...gRLRIMLVGVEADV........KDSWYRIKNVVAElwdlyNLSKKG----E.VSVDAIVKEIR..RTFPPQALVEALSL.RGYRAELLE.GNVIRTNAPLDVVLSLASRIAEVLE.EI.KFDVR.GTAAKRVVAAVAAAFDV.VPQ..EVIEVGLKADV....FE.hDEEGKIVLKREWRQAIR................
D7DR79_METV3/8-197                  ............sg----SEEETVE.ICEKVAK.lSLECSFDSKVKSTDGs.isSIMIKLYGNDRNKlk...edhKDILAIITDVKNK.....-YNANKKGMFT.YKLNDLK----..TPVNKDLIIDALKY.SKIKHEYIKeDNELLAKITAQELDDLLKDLQEIYV.DL.SYYPIgSKPVKNAIVIGVYISGL.EMD..EILELGLEEGC....FR..EEDDRIVLNMDITKVKN................
A0A150IYC8_9EURY/10-188             .........fkikg------NEKVE.IARFLS-..---KFEDISFNVCDD....TLKVKVL-NPGSM........GDIVYSIKSFLEEl..keKEIKEDKGIYS.YTLDSISKIAG..ATVPVKLLKAVLND.KGYSFEVD-.RENVVSTAHVSVAAEVAGDISYLLE.DL.DG--V.SKPVTEIIVRVAMEFDL.LSS..ELLNVGIEEKI....F-..NDSETVSLNISYDDAL-s...............
A8MB33_CALMQ/11-198                 ..............FKVRSTDEAVR.FINTYLS..EV-KAKEVYVKYRGS....RLEVKVRGNPVLA........KVLSTEAHKVYGT.....--LRQGRLINV.FDLTVIIREAKpkSPIPPETIELTLRL.MGYYAELN-.ESRLRTGASLSKVIETVRRLSEAYA.AM.VDLDI.SSSAKRIIASLAVAKGV.SIY..DAIDELVNMDV....LNkgKVNG-------------reyitlkanlndivn.
C6A1R4_THESM/9-196                  ..............IHVKDDLEKEE.LMKELQK.iELPAFIYVHGKLN--....SLKINIQGTKDEI........REAMEKVREIHYRv..rsRLYPDRKGFYQ.YNVNDIFREAG..VSISIPTLTKTLEL.LGEHADLK-.GDKLISSLSWGEIVNLVKKLGEVLT.DI.SLQT-.TRQIREVIAPISVTLNI.DPQ..EVLELAVDFGV....AEykEDKFKYELVKNKEQAM-e...............
A0A256ZWX9_9CREN/24-213             ..............ITIENDELREE.FLNKLLE..EL-KIDYVKVDVKGK....SIIITLYGTKDVI........NYNWNIIKRLRKElt.yiHMLKQPSKIKR.YLHSFLQKLSK..TTFPLEVLEVVLKG.KKFYAKIVD.DEVLETNASLDEVLELAKDIGRNLQ.EL.RLITK.SSAAKKFLASVMTILNL.DSE..EAKDLSLKLNI....AE.eDELGFIRLTKEWKEAV-r...............
G0HN60_THES4/10-197                 ..............IHVRDDREKEE.FMRELQR.lRLPAFIYVHGKLN--....DLKINVQGTKEDI........REAIRRIREIHNRv..raKLYPDKRGLYR.YTIDDIFREAG..ASVSTPILVKTLHL.LGETVEVR-.EGELVTSMPWEELVSLTGTLGGYLS.DI.SLQT-.TRQIREVVLPAAVAYDL.EPE..DVIDLLVELGL....AEwkEDKFKYELVKNKEQALE................
Y388_METJA/7-191                    .............s-KVSCDEELLE.LCERLSR.mDIDCTIES----KGN....RVRVYVFGYDKDSlk...xnyRTIREVMEKVKRK.....-YQKDDEGLYK.YPLFELK----..YPVNKNLIIDALKT.LGYKVIYLEdENAIKTNVDINKFNEILGELHELSQ.EL.RFSNLgSKPVKNLVVLVSYITKK.PVD..DVIEEALEKGF....FR..EEEGRIVLNKDINLAKK................
F2L3J3_THEU7/7-189                  ..............VKFSNGEELQQ.FLEILPK..YV-GVEYY-AIVRGT....NVYIQLNGSPDEI........KRALASIKTAVGL.....-VRARLKPVKS.YPLEVIYKESEivSPVPPDVLVDYLAV.KGFKARLR-.GLELQTDASMEQVRQAVSELSAAYK.SL.EGLPV.SPHAKRIAAVYIAAVKS.RPE..EALERLAAAGI....LS..-----------------rgsvfglaldlqtakr
E0SNR9_IGNAA/16-198                 ...........scp----NVDFCLN.ILEKIDE..ELSLESDIHVEFKNN....KLIFRVIGLEPNV........ISSINKIRNYISS....lQLVRSLNPGRG.ISSDDIAKLIR..KTIPLDVLGEVIKRdLGAHVKID-.KGVIYVDIDLDTLLSYAERVSRAMD.KV.SGLSF.SYSLKKLFIATIALYDS.NPM..EVLKILQDNNL....L-..--NENLELVVPWTKAL-d...............
A4WMI1_PYRAR/7-188                  ..............FKFSSREEVVR.FLSFLEK..HLKTTYLVTTRLD--....HVYVQLEGEEKEL........EEAAALVKRLAGL.....--ARQGRGVVQ.IPLLVLFRDANlaRPIPPDAVADALTL.SGVASHVR-.GDVLETSAPYEEVLKTAEALSRMYE.EA.ERLPL.TPQARKVAVAYAYARGV.PIE..KAVEELAEAGL....L-..NKGSVISLRYPLEEVR-r...............
A0A218P7S0_9EURY/10-197             ..............IHVRDDREKEE.FMRELQR.lRLPAFIYVHGKLN--....DLKINVQGTKDEI........REAIRKIREIHHRv..raKLYPDKRGLYR.YTVDDLLREAG..ASVSTPVLVKTLEL.LGENVELR-.DDELVTSMPWEEMVEVTERLGRYLS.DV.SLNT-.TRQIREVVLPVSVAFDL.DPE..EVIDILVDLGA....AEwkEDKFKYELVKNKEQALE................
A0A0V8RUH5_PYROC/11-197             .........vnapp-----GVPIEK.LYEKIGS..AL-RSNYAEVSIRDG....KVYVELVGTDYEI........KDTWYRVRQALAEl...wEIYKLE-TRRE.ASIEAIVKEAG..RTFPPEALVHALLL.RGYDARLSEdKSILYTDAPPEEVIELARRIAEVIE.GL.RFRVK.GAAAKRMIAALAAGLGE.DPE..RVIEYGLRSRV....LE..ETEEGLVLREEWRRGL-r...............
A0A0F7FI31_9CREN/8-193              ............lv--FSSPEEALE.FLEMLER..ILPGKSFL-GELKTN....KVKV-FVPESENS........EQVIRKIRELYNQ.....KRRPYAYGLVKdYDISTVFSLSRleQPIPLSLLITTLRI.QGYKAEAV-.RDKLRTNAPLDQLTKMVEKLSKLYG.EL.LEIKA.TAQARRLIALYSLTKNL.PTE..EAIRQLSEQGF....LT..EDRGRISLKLNYETALR................
A0A1Z2TL77_9EURY/10-197             ..............IHVRDDREKEE.FLRELQR.lRLPAFIYVHAKLN--....DLKINVQGTKEDI........REAIRRIREIHNRv..raKLYPDRRGLYR.YTIDDLLRESG..ASVSTPILVKTLEL.LGETVEVR-.EGELITSMPWEELVALTGTLGEYLS.DI.SLQT-.TRQIREVILPVAVLKGI.DPM..EVIDLLVGLGL....AEwkEDKFKYELVKNKEQALE................
B6YTH6_THEON/10-197                 ..............IHVRDDREKEE.FLRELQR.lRLPAFIYVHGKLN--....DLKINIQGTKEEI........RDAIHKIREIHNRv..raKLYPDRRGLYR.YTIDDLFREAG..ASVSTPILLKTLEL.LGETVEVK-.DGELVTSMPWEEIVELVETLGEYLS.DI.SLQT-.TRQIREVILPVAVVYDM.DPS..EVTDLLLELGL....AEwkEDKFKYELVKNKDQALE................
A0A150IXF5_9EURY/11-189             ..........fklk-----GNEKVE.IARFLS-..---KFQDISFDISGD....TLKVKIFDYG-NM........GDIIYSIKSYLEEl..keKNIKENEGIYS.YNLDSISKIAG..ATVPVKLLKVVLND.KGYSFEVQ-.KEDVVSTANVSVAADFAREISYLIE.DL.ED--V.SKPVMEILVRVAIEYDM.LAS..ELLNVGVEDEI....F-..NDTGTVSLNISYDEAL-s...............
S5ZDK7_9CREN/8-193                  .............l-NFDTPEEAIS.FLKLITS..RIKYSGLY-GEIKGK....KLK---------LfipesqrtEEVVNEVKTLYRE....lHGAKNAFQKKR.FKIQTVLSLAKleTAIPVPVLVDIIKL.QGKHARLA-.GETIETSLELNELVKLAEQVSSAYH.SA.IHMPL.TSSARRLLVVASLTLGK.NPE..ETVSLLLSRNL....LR..EEDGTLSLSMDYERSL-e...............
Q6M0K8_METMP/7-198                  ...........ikg----TEEEIIE.ICERISK.lGIDYSFDAKANYAENraynSARIKIFGDEKYKlv...edhKNILTIIDTVHNK.....-YNADTKGLFE.YKLNDLK----..YPVNKDLVLDTLSA.LKINFKYLKdENVIKCERKIEEINRILKDILDIYS.EL.NFYNIgSKPVKNVLTLAVYITGR.DID..ELIEEGLEKEL....FR..EEDEKIVLNKDINLTRK................
C5A5J4_THEGJ/9-198                  ..............IHVRDDREKEE.FMKELQR.lSLPAFIYVHGKLD--....SIKVNVQGTKEEI........REAIAKIRAIHNRv..raKLYPDRRGLYH.YSPDDVFREAG..TSVSLPIILKTLEL.LGERAEVDEaKGELVTSLPWDEIVELVRRLGLTLS.EI.ALQT-.TRQIREVVLPVSVAFDM.DPQ..EVLELLVDLGL....AEwkEDKFKYELVKNKEQALE................
A0A075M066_9EURY/10-197             ..............IHVKDDIEKEE.LMKEIQR.lNLPAFIYVHGKLN--....SLKINIQGTKDEI........REAMHKIRDIQKRv..haRLYTGKKGLYE.YTLEDIFRGSQ..ITVAAPILLKALEL.IGEKVSFD-.GEKLKTSLPWEDIVQLSRKLGDALS.QI.ALQT-.TRQIREVAIPVAVAYNL.DAE..EVLDKLVELGL....AEfkEDKFKYELIKNKEQALE................
Q8TZ80_METKA/11-198                 ..............FTFPDRDSAQR.FLRAVEA.tQARGVDTV-VELRGT....RVKVKVFGPHAAV........KAHIRKLGELRRT....vLSESEEEKQVR.LHLSTICREAG.aPKIPSELLRDALRR.RGYRVRVR-.GPWITTNAPMSELREFVRELAEAYR.EA.RFYAA.SEPVRRMLAILSHEYDV.DPM..DLAYEAIERGV....LR.eGEDGRCELREDPKSTE-r...............
A0A256XV84_9CREN/7-163              ..............FKFSNNELTTL.FIEELEE..NL-DVDTFSISVKGN....TVKITIVSRDRNK.......vFHAIEVIKETYGKv..rgIFSRDREGLYS.YPLEILFRNFL.nHPFPIDILIEILEK.RGYIAYLD-.QGHLRTNINFYEINELLLRIFKINQ.SL.IEKNI.DPSTREKLILQAF----.---..-----------....--..-----------------leese...........
A0A160VRE6_9EURY/9-196              ..............IHVRDDVEKEE.FMKEVQR.lNLSAFVYIHGKLN--....SLKVNVQGTKDEI........REALRAIREAHKRv..rgRLHPDRQGLFT.YSPDDIFREAS..ANVSLPILIRALEL.MGERVEVK-.DEYIKTSMPWREIVELVKKLNEVVN.QI.ALQT-.TRQIREVVAPVSVVYDI.DPE..ELLDLLVDLRL....AEykEDKFKYELIKNKEQALE................
I3TDP1_THEC1/8-194                  ........frvrcv-----SEPCEK.LAEMISE..HIALVGEYAITIHDN....WISIEFHGYESEI........KRAWARIKSLLAG.....-LPKAGRGGFS.LELNAMFRELG..STFPPRVLVEVLKR.RGFTAALDKdSNRVITNAGKEVVYELSKRIIELAK.RI.PGNVR.GLSTKYYLLTIGALTGI.PLE..EVLERALALSH....LR.kDEEGSIVLDIEWVQ---gv..............
D5TZM0_THEAM/10-196                 ..........vncr-----HNECIE.IIQRVSE..KLPSIDTVEYEVREG....GMLIEMYGYSTDI........KKAWTVIKEYIKH.....PGRQGGKGMFK.YSLKTLSKQAG..KTFPPAVLVKLLNL.KGFKAQYSSiDEAIHTDAGLEVLMDLINRVDAAVA.LV.RDKVK.GTAGKYYLTTLMIATGL.GLE..DVVNESLRLGH....LRvnEEDGLLTLAVEWDK---gv..............
W0I759_9EURY/9-196                  ..............IHVKDDVEKEE.FMKELQK.lNLPAFIYVHGKLD--....SLKINIQGTKDEI........KDAIYKIKDIHRRv..rsRLYANKRGLYR.YTLDDIFREAG..VSISAPILLKTLEL.LGETVELK-.DNELETSMSWNEIIALTRKLGEYLG.DI.SLQT-.TRQIREVALPLAIVFNI.DPE..EILDLMIELGV....AEykEDKFKYELVKNKEQAM-e...............
F8AIG5_PYRYC/9-196                  ..............IHVRDDVEKEE.FMKEIQR.lNTSAFVYIHGKLN--....SLKVNVQGTKDEI........REALRAIREVHKRv..rgRLYPDRQGLYH.YVPDDIFREAG..ANVSIPILIRALEL.LGEKVELK-.EEYIRTSMPWRDIVTLTKRLGEALA.QI.ALQT-.TRQIREVAVPVAVAFDL.DPE..DVLEKLVELGL....AEfkEDKFKYELVKNKEQAI-e...............
A3DM81_STAMF/12-199                 ............ck-----GDECFK.LAELIRE..KAPQVELVEIDITDT....GLYIEMYGYRTDI........KNAWEYIRRLVSSa..kaSEQYGKQGTRR.IKIEYLVEKKK..KTFSPVVLSEILKH.KGFKADLSDyKDEIVTDAPLEVIEEIIDNMWDILE.KI.KYDVR.GTTTKYFVTIASILTNK.DPQ..EVIMKAYSIGL....LF.kDEDEKYRLRKEWRKAI-s...............
E1QTA2_VULDI/11-204                 ..............FTFNNVNEALT.FMEMLTS..KIKSKELLIRYDTGSg..vRVWVSIQGEPHEV........ELYSMEIKRVYND....iKLMRGKFGTRA.YDVSLILSKARlsAAIPIDLIIDLLQI.KGINAELDGsKIRVVGDVKLEDLIKLAEDISRIYN.EL.IDAEV.SAQAKRIIALYALLMSK.GVK..DSIKELLDKGL....LSkyGDSELLVLSMDYKHAL-s...............
A0A100XX70_9EURY/10-197             ..............IHVRDDREKEE.FMRELQR.lRLPAFIYVHGKLN--....DLKINVQGTKEDI........REAIRRIREIHNRv..raKLYPDRRGLYR.YTIDDLFREAG..ASVSTPILVKTLEL.LGETVEVR-.EGELVTSMPWEELVSLTGTLGGYLS.DI.SLQT-.TRQIREVVLPAAVAYDL.GPE..DVIDLLVELGL....AEwkEDKFKYELVKNKEQALE................
O57821_PYRHO/9-196                  .............l-HVKDDVEKEE.FMKEIQR.mNLSAFVYIHGKLN--....SLKVNIQGTKDEI........REAIRAIREAHKRv..rgRLYPDRQGLYT.YYPEDIFKEAS..ANVSVPILIKALEL.MGERVEVK-.EDYIRTSMPWKEMVELVRRLSEVTA.EI.ALQT-.TRQIREVVVPVSVVYDL.DPE..DLLNILVDLGV....AEykEDKFKYELIKNKEQALE................
#=GC seq_cons                       ...............ph.sspEh.c.hhctlpc..pl.shhhsphclpts....plplpl.Gscp-l........+cshppI+clhpc.....thhtspcGhhp.Yslcslh+pst..tslshslLhcsLch.hGhpsclc..cshlhTshshcclhclsccluchhp.cl.phpsh.opps+cllssluhhhsh.ssc..-ll-hhl-hGl....hc..--ctphpLptshcpuh.................
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