GenomeNet

Database: Pfam
Entry: DUF2120
LinkDB: DUF2120
Original site: DUF2120 
#=GF ID   DUF2120
#=GF AC   PF09893.10
#=GF DE   Uncharacterized protein conserved in archaea (DUF2120)
#=GF AU   COGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   COGs (COG4077)
#=GF GA   25.30 25.30;
#=GF TC   25.90 116.10;
#=GF NC   25.00 25.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR014515;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This domain, found in various hypothetical archaeal proteins,
#=GF CC   has no known function.
#=GF SQ   31
#=GS Y491_METJA/29-162       AC Q57914.1
#=GS D7DUD8_METV3/5-137      AC D7DUD8.1
#=GS A0A366M7Z2_9EURY/6-141  AC A0A366M7Z2.1
#=GS D3E099_METRM/7-142      AC D3E099.1
#=GS A0A166BQT8_9EURY/6-141  AC A0A166BQT8.1
#=GS D5VSW0_METIM/5-133      AC D5VSW0.1
#=GS F0T8N8_METLA/5-140      AC F0T8N8.1
#=GS A0A1D2W5T8_9EURY/1-129  AC A0A1D2W5T8.1
#=GS A0A328SPZ5_9EURY/5-141  AC A0A328SPZ5.1
#=GS E3GY16_METFV/10-145     AC E3GY16.1
#=GS Q8TY22_METKA/12-175     AC Q8TY22.1
#=GS A0A0U3DV11_9EURY/6-141  AC A0A0U3DV11.1
#=GS A0A328SBL6_9EURY/8-145  AC A0A328SBL6.1
#=GS A0A328RZY0_9EURY/5-141  AC A0A328RZY0.1
#=GS O27265_METTH/6-141      AC O27265.1
#=GS A0A166CBE5_9EURY/1-132  AC A0A166CBE5.1
#=GS R9SLX4_9EURY/6-142      AC R9SLX4.1
#=GS A0A1D2WJR7_9EURY/6-141  AC A0A1D2WJR7.1
#=GS A0A2Z4L8W4_9EURY/5-142  AC A0A2Z4L8W4.1
#=GS A0A166FHN2_9EURY/6-141  AC A0A166FHN2.1
#=GS A0A328SNS3_9EURY/5-142  AC A0A328SNS3.1
#=GS U6EC70_9EURY/5-140      AC U6EC70.1
#=GS F6BCH8_METIK/5-137      AC F6BCH8.1
#=GS A0A1D3L4M7_9EURY/6-141  AC A0A1D3L4M7.1
#=GS A0A165ZBL0_9EURY/6-141  AC A0A165ZBL0.1
#=GS A0A328S3C9_9EURY/5-141  AC A0A328S3C9.1
#=GS Q2NI41_METST/5-141      AC Q2NI41.1
#=GS A0A2U1S6Q1_9EURY/6-140  AC A0A2U1S6Q1.1
#=GS Q6LX32_METMP/9-141      AC Q6LX32.1
#=GS A0A1V6N0Z2_9EURY/6-141  AC A0A1V6N0Z2.1
#=GS A6UVS5_META3/5-138      AC A6UVS5.1
Y491_METJA/29-162                  vn--IGRLMHALNAFKGSKPLFETDEMLMVKGVCRDEE-.VEKYGSIKDYLVKKLEKEGFEIVEDikEIDKFVSRINE................ILKE-NPLY--PDTF..........GFERMKESFEMIGCECDYVIAKK..RNIMVGVCMYFDKKMKNPKFVEVV-g.
D7DUD8_METV3/5-137                 vk--IGKIVRSLDAFKGSKPVVNKEEMIAVRSICRDLE-.FNDYNSIKEYLEAKIKQNGYELMDE.dDKLIMVNRINE................IMDE-KGIF--PDEM..........GFDALKASFENIGCKCDYALGKK..DNLMLGISMWYNEEDDLHKFVEVMV..
A0A366M7Z2_9EURY/6-141             ..KIAGKVISFFEAFDGSRAALDTERILIVRGKSSKNIP.LDEMEEQLEKIKDLIEGKEVGVVSD..EAGKLINRMDE................QIRSNVSVQGDTDVN..........GIMRMTKSLEAMNVCVKFKLMNL..AHTAAFVVIWKDKSDFGPLFVETVV..
D3E099_METRM/7-142                 ..KITGQIIGHFNAFKGSRPAFHGEHTLIVRGISRDKIE.IEEMEPKLAELEDILKAREVDVLSD..AGKNFVEKVDS................YIRDAESIDTAPDSG..........GLLRMKEQLETMGLHVEYKLFLM..PYAGAFVAIWKDKSGFGPLYVEVT-a.
A0A166BQT8_9EURY/6-141             ..KIAGQIVKFLDAFEGSRAALDAQLILIIRARSSKNIK.IDELEEKLEKLIEHMEGHEIPEISD..DAGKLINRMDE................QIRSSMQINGETDIG..........GVSRMKKSFEALNVAVEYKFFEI..PTAGIFVAIWKDKADVGPVYIEFVV..
D5VSW0_METIM/5-133                 ev---GKLMMRLKAFRGCRPLFECDDMLIVKGICRDQV-.-DNIKS---YLEEKLKEENFEIVEDeeEIKEFVESIHE................RLRGGEEYL---DPF..........GFEKMKEAFKITGFECDYCIGKK..KNLMVGVSMYYDRIRKEPKFVEVVA..
F0T8N8_METLA/5-140                 ..EIAGKVMNELEAFHGSKPAIDTPQILIVRGMSRKRID.PEELSSIISGTMKGLGARTIDVFSE..EATDIIGIMDE................NIRSTVEIPGETDVY..........GIYRLKESFESMNCHTEYSLGII..GKLAVFLVLWKDKSGMGPLFVELVV..
A0A1D2W5T8_9EURY/1-129             ..------MGDLEAFHGSKPAIDADNILIVRGMSRKQF-.NEELDEVLSNLLKKLGARQIDMFSE..EGGNMIGIMDE................RIRESVDIPGETDIT..........GVYLLKESLEAMNCNVAYTLGLI..DNVGTFIVTWKDKSGIGPQFVEVVA..
A0A328SPZ5_9EURY/5-141             qm--SRPIMEYLDAFKGCKPVVHSTESMIVRGKTHNKFE.ADEMLPKLLEMFEHFNIKNIEKESK..KAREITDKADG................IFRKTEEVYDESNGL.........dGIERIKQVFESTGFNAEYVIGEI..DDLAIYVVLYTDKSGFGPMFVETMV..
E3GY16_METFV/10-145                ..NVAKEILLHFNAFEGSKPLFDSQKILIVRGASRKKMD.REKIKKELEKLLEKLDAKEVDLMSG..EGSNILAMMDN................NIRLEIDPEAESDFM..........GIEKLKETFEQMNFIVEYKLARK..NNIGIFVVVYKDKADVGPCFIEVVV..
Q8TY22_METKA/12-175                ..RLAKKIMMELDAFEGSRPLLDDVDVLIVRGMSRGEDWdLDNLQGYLESVLERCDVEVVDPESP..EGKELIEELGKfvveriqaqyadeepvSVRPVENPMEAVDAFtqgeifldplGFERLKRDLEALGCVAAYTFGRT.pDDLGVFLAAWADRSGIGPKSVELLV..
A0A0U3DV11_9EURY/6-141             ..EIAGSVMGFFDSFKGSAPAIDNDKILIVRSRSRKILP.INELEDKISEIGKEIGGVEVPATSD..KIEQILKSGDK................HIKESEVATGDIDFR..........GFTRVKKELESMGLVVAYKVYEL..PSFDVIIAIWEDKNELPPLYVEVTV..
A0A328SBL6_9EURY/8-145             .e-VSRQVMDYLDAFKGSKPVLHEQEAMIIRGKSANRLK.PEDLMTKLEELFKDLNIKEVQSSST..RASTLTQRVDE................KLHKVTEVYDESNGI.........aGIEKLKQSFEMTGFKADYKIGEL.pSDIVVYVVLWLDKSGFGPMFVESM-a.
A0A328RZY0_9EURY/5-141             .e-LSRKIMDYLGAFKGSRPVVHNPEAMIIRGKAEHKLK.PEEILPKLNDLFKDLGIKKVQVNSE..RARVLTDQVDA................TFRKTTNVFDESHGI.........aGIEKLKHTFEITGFEADYLVGEI..EDIATYVVMWMDKSGFGPMFVEAMV..
O27265_METTH/6-141                 ..RIAGEIMGFFEAFEGSRPALDSREILIVRGMSRKRMN.ADDMSRELDSLIEHLGAAELDLLSE..EGAALIGVMDE................QIRSCVEVGTETDIG..........GIHRLKESLEDMNFSVEYRLCMA..DETGLFVVLYRDRSGVGPCFVEAVV..
A0A166CBE5_9EURY/1-132             ..------MRILDAFKGSRPAIETQFILIVRSLSDKDLS.INDFGKTLDDLIEELNGTKIGDFSD..KASKLINRMDE................QIRANVHIGGDSDSA..........GIERMKRSLEELNVFSEYRLFEIpeMHVGVFLVMWKEKSDKGPIFVEVVV..
R9SLX4_9EURY/6-142                 ..KIAGRVMGEFNSFKGSRPALDNGELLVVRSVCQGNIDiHNEVDEKLDNLVKELNGREVNVVSD..EAGKIINKMDE................QVRTTVKINETADSN..........GVIRMAHDLEQMGLTVKYRLFRM..EHADVFVVLWKDKNNNGPCFIETT-i.
A0A1D2WJR7_9EURY/6-141             ..EIAGQVMGFFESFKGSRPAINNDRILIVRGRSRKIIP.INEFDSKLSEIGEILGGTELNASSE..KISEILQYGDK................NIQKSEGNTTSIDEH..........GFTRMKDELESMGLVVAYKVFEL..LGFDVVIAIWEDRNELPPLYVEVTV..
A0A2Z4L8W4_9EURY/5-142             .e-VSRQIMEYLGVFKGSKPVLHNTEAMIIKGKTHDKLK.QDEIIPKLEELFEHLNIRRVYLSSQ..KAKKFTDRADK................KLRKVAEVYDESAGI.........sGLERMKMSFEMTGCVAEYMIGEM.dSDIVVYVMVWFDKSEYWPMFVES--av
A0A166FHN2_9EURY/6-141             ..KIAGKVIEHLEAFKGSRAAMDSEMILIVRGTSSQKIA.ISEMGKKLEEILEILEGTEVDSVSE..EASKLINRMDE................QIRSNITINGDTDSN..........GIMRMKKSLEELNLAVEFKLMNL..AHAGVFVVIWKDKADVGPIFVEVVV..
A0A328SNS3_9EURY/5-142             .e-VSRQIMEYLGVFEGSKPVLHDADAMIIKGKTHDKLK.EDEITPKLEELFEHLNIKRVYLTSQ..KAKSLTDRADK................KLRKVAEVYDESAGI.........sGLERMKQSFEMTGCTADYMIGQM.dSDIVVYVMVWFDKSDYWPMFVES--av
U6EC70_9EURY/5-140                 ..EIAGHIMGKLDAFEGSKAAMDTTELLIVRGRSRLRIP.AEELESTIDQILKELGARKLDMFSD..EAADIITIMDE................QIRAQVPIQEETDIY..........GIYRLKESFEHMNCHADYGMGVV..DDIAIFIILWKDKSGMGPLFVELVV..
F6BCH8_METIK/5-137                 mt--VGKIMQSLNAFKGSKPICDIEGLLIVRGVCRDEN-.FEKYNSIKEYLEAKLKENGFEIADE.dDIVLFVERINN................VLKE---TMASPDMF..........GFEALKKSFESIGCECDYVIGKK..GNLMVGVSMWFDKNRKNPKFVEVV-g.
A0A1D3L4M7_9EURY/6-141             ..EVAGRIMYELEAFDKSRPSIDSPQILIVRGMSKKRVD.HQEMPSLLSDLMKKLGARRVDIISE..EGGDIIGAMDE................GIRACVDVNAETDVQ..........GIMRMKESFEGMNCHVEYGMGVL..GKIALFIILWKDKSGMGPMFVELVV..
A0A165ZBL0_9EURY/6-141             ..EIAGQVMGFFDAFKGSRPAIDNDEILIVRGKSRKIIP.INEFSLKLSKIGEQLGGSEIEASSE..KITEILKSGDK................HIQKNDLNSANIDNR..........GFIRMQKELESLGLVVEYKVFEL..PNFDVVIAIWEDKNELPPLYVEVTV..
A0A328S3C9_9EURY/5-141             .a-VSRPIMEKMDAFKGCKPVVHSTESVIIRGKTHNKVK.PENMYPRLLELFNELNIEKIEKESE..KARKITDQIDS................VFRKTEEVYDESNGL.........eGIERLKKTFEMTGFHAEYAIGQI..DDLVVYVVLYMDKSGFGPMFVETMV..
Q2NI41_METST/5-141                 ..EVSRKIMDYLDAFKGSKPVVHNSEAMIIRGKSATKLK.PEEIVPKLEELFKELNIEKIEINSE..RARILTNQVDQ................TFRNTTEVFDESNGI.........aGIEKLKHTFEITGFEADYLVGQL..EDMAIYVVMWLDKSGFGPMFVEAMV..
A0A2U1S6Q1_9EURY/6-140             ..EVAGQVMGFFDAFKGSQPAIDNEKILIVRGRSRSVIP.LDQFHDKINEIGELLGGKEVT-SDE..KIRDILELGDK................HIQSKEEPTTAVDSH..........GFTRMKKELEGMGLVVEYKVFEL..PDCDVIIAIWEDKHELPPLYVEVTV..
Q6LX32_METMP/9-141                 .v-VMGRIVKSMEAFRGSKPVINKEGILSVRSVCRDPE-.FEKYNSIKEYLTEKLVQNGFELANE.dDILDMVAKINN................LIGD-SETY--GDEF..........AFEGVKSGFEDIGCDCDYAIGKK..GGVYIGISMWYEKVSKDPKFVEVMA..
A0A1V6N0Z2_9EURY/6-141             ..KIAGQVMGFFEAFDGSRAALDTDRILIVRGRSSKNIS.IDDMESKLDELRDHLEGIDVDVVSE..EAAKLINRMDE................QIRASVSVQGDTDSN..........GIMRMTKSLEAMNLFVKFRLMNL..NHSGVFIVTWKDKANVGPLFVEVVV..
A6UVS5_META3/5-138                 .v-TTGRIIKSLEAFKGSKPIYEKNGLLIVRSVCRDKK-.FEEFDSIKEYLKSKLVENKLELPDD.eDINIFIEKIDE................KIGEGSDIY--PDAF..........GFEMLKKSFENMGCECDYIIGKK..GELFVGICLWYDKVVKKPIFVEVIC..
#=GC seq_cons                      ...luGplMthL-AF+GS+Psl-ssclLIVRGhS+ccl..h--hpspL-cLhccLstccl-hhS-..cupcllsphDc................plRps.plhs-sDsh..........GlpRhKcohEthGhps-Ytluch..sclslalslWtDKushGPhFVElsV..
//
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