GenomeNet

Database: Pfam
Entry: DUF2321
LinkDB: DUF2321
Original site: DUF2321 
#=GF ID   DUF2321
#=GF AC   PF10083.10
#=GF DE   Uncharacterized protein conserved in bacteria (DUF2321)
#=GF AU   COGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   COGs (COG4306)
#=GF GA   23.20 23.20;
#=GF TC   23.40 24.20;
#=GF NC   23.00 23.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR016891;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Members of this family of hypothetical bacterial proteins have
#=GF CC   no known function.
#=GF SQ   41
#=GS Q3A032_PELCD/5-159        AC Q3A032.2
#=GS E8X823_GRATM/2-155        AC E8X823.1
#=GS L9VEB5_9EURY/1-104        AC L9VEB5.1
#=GS A0A1N6EYL4_9BRAD/86-162   AC A0A1N6EYL4.1
#=GS A0A0F5FMF3_9RHIZ/5-155    AC A0A0F5FMF3.1
#=GS Q97HR5_CLOAB/3-160        AC Q97HR5.1
#=GS A0A3N1UQR3_9DELT/5-159    AC A0A3N1UQR3.1
#=GS A0A1I4HIZ6_9FIRM/1-73     AC A0A1I4HIZ6.1
#=GS A0A0M0XD86_9BACI/3-157    AC A0A0M0XD86.1
#=GS A0A1I0R250_9BACT/3-104    AC A0A1I0R250.1
#=GS A0A2T4V0Y6_9DELT/6-149    AC A0A2T4V0Y6.1
#=GS A0A1Q8QJK5_9FIRM/1-68     AC A0A1Q8QJK5.1
#=GS A0A3A9CXG3_9CLOT/3-152    AC A0A3A9CXG3.1
#=GS A0A447FV31_9LACO/1-64     AC A0A447FV31.1
#=GS A0A3N1KRN6_9PROT/1-67     AC A0A3N1KRN6.1
#=GS A0A0R1RJ08_9LACO/3-155    AC A0A0R1RJ08.1
#=GS A0A256B8R3_9CYAN/3-98     AC A0A256B8R3.1
#=GS Q8XW60_RALSO/3-158        AC Q8XW60.1
#=GS A0A2P8E3X9_9ACTN/21-166   AC A0A2P8E3X9.1
#=GS Q9PFM7_XYLFA/3-158        AC Q9PFM7.1
#=GS A3ZP13_9PLAN/1-118        AC A3ZP13.1
#=GS R6DLN7_9FIRM/3-153        AC R6DLN7.1
#=GS Q65PN4_LACJO/3-155        AC Q65PN4.1
#=GS A1ZK27_9BACT/8-97         AC A1ZK27.1
#=GS B2A6L3_NATTJ/23-177       AC B2A6L3.1
#=GS I4D747_DESAJ/20-98        AC I4D747.1
#=GS Q2RQ80_RHORT/14-169       AC Q2RQ80.1
#=GS G9ZRP6_9LACO/3-162        AC G9ZRP6.1
#=GS M0BZZ7_9EURY/5-102        AC M0BZZ7.1
#=GS A0A0R1N080_9LACO/1-70     AC A0A0R1N080.1
#=GS A0A0G2ZGW2_9BACT/3-156    AC A0A0G2ZGW2.1
#=GS A0A1Q1PVY6_9CAUD/4-154    AC A0A1Q1PVY6.1
#=GS I6T3M4_ENTHA/8-164        AC I6T3M4.1
#=GS C0GE89_9FIRM/3-158        AC C0GE89.1
#=GS V7FLP4_9RHIZ/12-166       AC V7FLP4.1
#=GS U3PDZ3_9CAUD/3-153        AC U3PDZ3.1
#=GS Q6SEF3_9CAUD/3-155        AC Q6SEF3.1
#=GS A0A261FF77_9BIFI/114-197  AC A0A261FF77.1
#=GS A0A3E0E045_9FLAO/9-126    AC A0A3E0E045.1
#=GS A0A0R1HFY6_9LACO/44-198   AC A0A0R1HFY6.1
#=GS Q88LJ9_PSEPK/3-95         AC Q88LJ9.2
Q3A032_PELCD/5-159                   ......................................YYDVAQICINGHVINS..MAKDYPQSNQKYCSDCGEETITACPSCG.SNI....RGH....YHVP.....GVISFS....-..NFHAPSYCFNCGSPYPWT.AI..RLEAAAELADELDGLTTDEKEKLKSSLPDLVKD..GPKTVVAETRFKKIIKK.AGADAYEGMKTILVDVVSETVKKS-m................................
E8X823_GRATM/2-155                   gfaaycknghlvgivqsprtgsdlrrlaerhatgipff----------------..---------SPFCKECGEATVSQCPHCE.ARI....ELN....----.....------....-..----AKYCGSCGKVLPWT.EN..ALAAARAYTDDLDEFTSDEKEKLNENFKVLTKD..SPSVPLAVRLLQKAVAK.AGPVVGSAILEIAKTLATAEAKK--hl...............................
L9VEB5_9EURY/1-104                   ...................................mtv----GAVCEDGHIRVI..EAEHEDIEHDPYCRKCGNQLHSVCPNCNnAPV....KLD....GYTR.....DN---G....S.pHWRVQEYCHNCGEAYPWGpSR..FMEVTREVAKRLPE-------------------..-----------------.-------------------------pqdsrpsgrv.......................
A0A1N6EYL4_9BRAD/86-162              .........................hreaemrkligll----------------..----------------------------.---....---....----.....------....-..------------------.--..-----------EEPLDHSEKAAVPAVVQNVMTE..TSFTPLAAERLKSMLSR.LGKSAYDVAIKIISDIGSATVKKM-l................................
A0A0F5FMF3_9RHIZ/5-155               ...................................hfl---TGQACLNGHIVTG..NINDRDS--TPFCAECGEATINACLSCT.KPL....RGA....YETE.....Y----G....Y.yPMKLPAFCYACGRPFPWT.ER..RVQTAKDLADEVEGLDGAELTKAKDSFIVLVSD..TPQTPVAAARVTKLLQK.AGPVIGGGIRDIVVSIATDAAKRM-m................................
Q97HR5_CLOAB/3-160                   ......................................TYRTAQICLNGHEITT..SANTSPELMENFCSKCGAATITNCPICN.TPI....RGS....YHVE.....GVLSLG....H..EYKIPSYCHNCGKPYPWT.KT..ALESANALIEEDENLNSDEKKQFCETLPDLIVEspTPKTQLATARFKRLISK.AATYTTDGVKGIIVNIASEAIKKS-l................................
A0A3N1UQR3_9DELT/5-159               ......................................YYDMAQICRNGHVITS..MAQSSPQSKQKFFSKCGEETVTACDSRG.API....RGY....YHVP.....GVIAP-....L..DYQKPAYCYNCGSPYSWT.VK..GIEAASELADELEGLTDDEKAQLKNSLPDLVNN..SARRTVAEIKFKKIMKK.AGSQAIAAMKEILFNVVNETVKKS-l................................
A0A1I4HIZ6_9FIRM/1-73                .....................................m----------------..----------------------------.---....---....----.....------....-..------------------.--..---AAKEYVDFMEELSSEEKEALKNNIDDIITD..SPRTKLASQKVKYYLTK.VGKGLATGLKDILIDFASETAKKII.................................
A0A0M0XD86_9BACI/3-157               .....................................s-FDIAQICLNGHVIND..TYVKYPETNQKYCDKCGEKTIISCQNCH.TDI....RGY....QYFE.....NVISMS....-..MVEPPSFCHECGKPYPWT.EE..KMAAAMELADLLDELTEQEKDDLKKSLDELVKD..GPRTVVAATKFKRILSK.TGPEIATGFKDILVDVVSETVKKSI.................................
A0A1I0R250_9BACT/3-104               .....................................k-QDTQEVCLNGHQITD..RYYSSPEFRKKFCTTCGEKTIHTCPSCA.KDI....KGH....MIYE.....NVIDLS....G.rSTPVPNICDNCGADFPWR.EK..KQ-------------------------------..-----------------.-------------------------kikelsnptnvekdatfl...............
A0A2T4V0Y6_9DELT/6-149               ..................................spgd----------------..---------AAFCRDCGARAVKTCGQCS.AHI....QGV....RIPPlhtrrDFSMLPspeaQ..PYRIPAHCPQCGHAYPWT.EA..RLKAAAELVDLAEALSAEERAQLKADLPALANE..GPQSPVTAQRWKKGLAK.VGGDLYGVRMKVLGDLVTASVK---gql..............................
A0A1Q8QJK5_9FIRM/1-68                ....................................mv----------------..----------------------------.---....---....----.....------....-..------------------.--..----------EYSKLNAADKKEFVDNIEIIASD..NPRTSLAAIKIKSIGKKlAGGLWNDVAKPLIVEIASETAKKS-m................................
A0A3A9CXG3_9CLOT/3-152               .....................................i-YNSATICLNGHVISS..TRF----DYTSYCDKCGNKSISICPSCN.TVI....RGA....YENE.....I--AID....F..HYQAPSFCYSCGNPFPWI.ET..LINNAVELIALDDNLSEENKAIIKSALPDLIVE..TPTTPLAAAKYKKFVPK.AAKYIQDGLRNLLVDVASEAVKKS-l................................
A0A447FV31_9LACO/1-64                .....................................m----------------..----------------------------.---....---....----.....------....-..------------------.--..------------SDLNQNDKEDFKETIPNILTD..TPKTKVATTKFTVYAKK.ISSSLGSAIHDILVDVVSEAVKKAI.................................
A0A3N1KRN6_9PROT/1-67                .....................................m----------------..----------------------------.---....---....----.....------....-..------------------.--..---------DEMDELSDDEKRTLKQSVAEMTRD..TSATELASVRYKKLLGK.AGKGIGTALNSVTVSVITEAAKRL-l................................
A0A0R1RJ08_9LACO/3-155               .....................................t-KHKQLVCLNGHQIKD..AMELSDSE-SGFCNKCGQPLISSCPKCG.HYI....PGT....TDYE.....GVISFF....-..QEPVPKYCSNCGAPYPWT.ES..VLKSATELIE-LTDLSQQDKDSFSKTIPDLVTD..TPKTKVAIAKFKIFSAK.AGKTVASGLKDLLVDVASEAVKKAI.................................
A0A256B8R3_9CYAN/3-98                ......................................YYDTQQVCLNGHQTTD..NYHRSPEFRQKFCATCGAETIHKCPNCN.SEI....RGD....YHID.....GVFDFS....-..RTPVPIHCENCGADFPWT.KN..K--------------------------------..-----------------.-------------------------eklsaknfesvsvdh..................
Q8XW60_RALSO/3-158                   ......................................TYRVAQVCPNGHVATT..AADQNPELREAFCSKCGEETIMQCPSCS.ASI....RGD....FYVE.....GVFGLG....G..DYEPPSFCHNCGSRFPWT.ER..KIAGAVELVEAGAELSPEEVQQFRTDLTELTKD..SPKTQVASLRFKKVMTK.VGASVASGVRDIVVDVLSEAAKKAI.................................
A0A2P8E3X9_9ACTN/21-166              .....................................f-YLGAAVCKRGHVETV.dLEPGGPVTVSDACPSCGARMLTACRSCG.VRI....RGD....QFVP.....GVVSFS....-..TPRRPSFCDGCGAAMPWA.TRqeRIHELENLLDEAEEIDEADLVVIQDHLERL---..-----------------.-------------------------resslserdekaawsevkrrsgdalrservsnv
Q9PFM7_XYLFA/3-158                   ......................................TYRAAQICTNGHVATT..AADQKHELWEAFCSHSGEATILQYPKCS.ASI....RGD....DYVE.....GVLGFG....G..DYEPPTFCNNCGSRFPWA.ER..KIAGTVELVEAGTDLTPDEVQQFRTDLTQLTKD..SPKTQVTCLRFKKVMAK.VRTSVASGVRDIVVDVLSEAAKKAI.................................
A3ZP13_9PLAN/1-118                   .....................................m----------------..----------------------ACPDCQ.SPI....QGH....YHCP.....GVIGFF....-..DYDAPHYCQNCGKAFPWT.TR..ALEAARQLATDDDTLSADESERFAKDLEEITRE..TPQAKASAGRIKKMLGK.MTAGTGAAIRDILIDIASESVRKMI.................................
R6DLN7_9FIRM/3-153                   .....................................p-YHIAQVCTSGHLITD..CFDVLEYERRNFCPKCGAPTITKCPACG.SEI....YGA....--IE.....GS---R....C..DTTVDAYCSFCGTPYPWT.SA..ALQSAKAIIEEAPELSDELKANTSGSLSDILVE..TPGTNLAIVRLKKVLQC.AEKFTCDALRQFVIDFGCELAKRS-l................................
Q65PN4_LACJO/3-155                   ......................................TQYKQSICLNGHQITD..EFS-PNETVTGYCEQCGAKLIDSCPHCK.YPI....EGF....YYPD.....GVVYLRs..pN.dKLPVPKYCKKCGTPYPWT.KD..SLDALNEVIQ-LSNLSIQDKESLQASTPDLLVD..TPRTKVAVLKWKTI---.-GKSILNLAHDIIVEVASESITKAI.................................
A1ZK27_9BACT/8-97                    .....................................n-QDVMQVCLNGHQITD..SYLRSPHLAEDYCQKCGKETIVACPNCQ.TPI....KGD....YYYP.....GVVDLT....G.fRTPVPKRCSNCGKYYPWG.KK..---------------------------------..-----------------.-------------------------lekvqrsk.........................
B2A6L3_NATTJ/23-177                  .....................................w-YDVAEICMNGHVTNS..SVNKNSQHCQDYCEKCGEKTIRECQDCS.TPI....RGK....LHVE.....G--GFG....S.tHYYAPSYCHKCGNPFPWT.EA..TLKAAKELAQEVEEFSQEDIDIFTASLDDLIVD..NPHTKVAAVKFKKILSK.AQQPMKDAIYQLLIDTVSETARKIV.................................
I4D747_DESAJ/20-98                   .............tyyminrssmkvtesetkdfetfna----------------..------------------KNISNCIKCN.AFI....GGV....----.....------....-..---ESSYCHQCGTPYPWA.LN..KYNDLIKMVE-YFELNPEDA-------------..-----------------.-------------------------ec...............................
Q2RQ80_RHORT/14-169                  ......................................YYLTAQVCGNGHHTTS..SVEHSPNLMANFCDKCGSETMTKCPSCS.TKI....RGK....YYVD.....DFAIIG....Q..NYTAPSFCHACGKAFPWT.TT..KIEAAKEMVEEIDELSPDEREKLKGAIDDIVIE..GARTELGANRFKKLLTK.MGSASASAMRDIVVDVISETAKKII.................................
G9ZRP6_9LACO/3-162                   .....................................i-QYAQSVCLNGHQASD..NVSWGVQT-TGFCDKCGAKLISICPSCK.NPI....PGSidpnDYNS.....DVFILG....GptVTPVPKYCNSCGKPYPWT.QS..AIDSAKELIE-MSELDSTDKESFNESIPDLLVD..TPKTKLAITKFKIYTSK.IGSGIADGLKEVLVDVVSETVKRAI.................................
M0BZZ7_9EURY/5-102                   .................................fdfde----------------..STEPDYEISSDYCPDCGGKVLTECRNCQ.SNI....QIE....YNGP.....PY---P....N..LTHIPDFCDSCGESYPWV.D-..---------------------------------..-----------------.-------------------------pvesekqregdfieiddtdidghfypelvyei.
A0A0R1N080_9LACO/1-70                .....................................m----------------..----------------------------.---....---....----.....------....-..------------------.--..------QLLNRSSKFSDQDQAEFAQIIPHLIIE..TEYTKSAKNKYQCLIRK.AGPATTNGLKEILAKVCSADVRKS-l................................
A0A0G2ZGW2_9BACT/3-156               ......................................TYHKALICKNGHIITD..TIDTQPEKYEKYCSKCGAETIKKCEHCG.AFI....RGD....YEIP.....GFVTIG....F..PPELPKYCHNCGKPYPWT.EK..SIEAAKELLMELDSGY--GEDFLNKTVEDLISD..DPETKVAIVRIKKMLAK.ASPEIGKLLKDILVGVVSEGVRKMI.................................
A0A1Q1PVY6_9CAUD/4-154               ......................................YYENATICLNGHVASS..QVS----NYIKFCKTCGESTISNCLKCE.FPI....EGS....YRTR.....DFIDFT....-..TYNPPNYCHECGTAYPWT.EK..ILNNIIELVSLDDELSQEHRTIIKNAIPDLIID..SPTTPLAQAKYKKYMSQ.AAEYVQEGARNLLIDLVSEAVKKS-l................................
I6T3M4_ENTHA/8-164                   ......................................TQYFQKVCTNGHQISDrsTINSDPQP-EEYCEECGSKVITTCPTCR.IPI....LGH....KTID.....GVITLG....Y..ITPVPQYCRHCSNPYPWT.SL..ILESAVELLSLDEDLPDSDKLLIKTAIPDLLVD..TPKTKLAEAKFKKGFSN.ASKLVKDSLYNLLVDVLSESVKKTI.................................
C0GE89_9FIRM/3-158                   .....................................r-YDEALICKNGHVINE..SANRNPEFNTKFCDKCGAETIRKCLNCG.TGI....RGE....YHVE.....GVFDLT....G..HSPAPSYCHDCGKPYPWI.EE..QLNALDEIVDLMDELSELEKQEFKQSAREVTTE..NPRTSLAALKIKKFGIK.VGSEVYGAARDILVQIAVEAALKS-s................................
V7FLP4_9RHIZ/12-166                  .....................................i-YKVGQVCVNGHAITG..NVEAA--ASSKFCPRCGEETIVTCPSCR.ASI....RGN....RIIR....sDFGNIS....S..GMHIPAFCHACGKPFPWT.ER..AVAAAKELVDEVEGIETDEREKAKSSFIALASD..TAQTTVAATRVNKLIAK.AGPILGKGIRDIVVSIATDAAKKA-m................................
U3PDZ3_9CAUD/3-153                   ......................................YYENATICLNGHVS-S..SIN---AKYRKFCKECGESTISNCLNCG.SAI....QGS....YCIP.....NFIGPS....-..DFQFPNYCHECGNPYPWT.EK..LLNNAVELVSLDEELNENQKEIIKNAIPDLIIE..SSSTPVAQAKYKKYMSL.AAEYVQEGTRNLLIDVVSETVKKS-l................................
Q6SEF3_9CAUD/3-155                   ......................................TQYKQSICLNGHQITD..EFS-PNETVTGYCEQCGAKLIDSCPHCK.YPI....EGF....YYPD.....GVVYLRs..pN.dKLPVPKYCKKCGTPYPWT.KD..SLDALNEVIQ-LSNLSIQDKESLQASTPDLLVD..TPRTKVAVLKWKTI---.-GKSILNLAHDIIVEVASESITKAI.................................
A0A261FF77_9BIFI/114-197             ..................................rppw----------------..---------------------SKCPRCG.AAIfgcvEGM....TDIE.....EIERLL....K..NTPAPYWCRSCGQRFKFT.GN..WLSCTDEFTVE----------------------..-----------------.-------------------------etiesikhvfptqqpsfdtlq............
A0A3E0E045_9FLAO/9-126               .....................................f-YDVMQVCVNGHLITD..NYYTSPEFRKSFCTSCGEKTITTCPNCN.KEL....KGD....YHVP.....GVVDLS....F.sRTPVPEICEYCGKDFPWK.SK..K----KKIAESAKSLNP----------------..-----------------.-------------------------dnifiinqicerfhlvtkqlrqr..........
A0A0R1HFY6_9LACO/44-198              ......................................TQYSQSVCLKGHQISS..FITTSSENPKEFCEDCGSEVITHCPSCN.KSI....NGY....LQLD.....GV--FG....G.yDVPVPSYCRNCSSPYPWT.ST..ALESLKELINLQDELNDEEKDDFSSSLPDLISN..GPKSKVAITKFNKYSSK.ISSGFRNFAVEIISSIASDVIVKS-l................................
Q88LJ9_PSEPK/3-95                    .....................................q-QDAQQVCLNGHQITD..SYHRSREFRQRHCSQCGAETIHQCQSCG.IEI....RGD....YHVE.....GFLALG....D..PTPIPANCEGCGTQFPWA.QR..KQEL-----------------------------..-----------------.-------------------------aasagdpt.........................
#=GC seq_cons                        ..........................................ttlChNGH.hss..th.......ptaCppCGtpsIppC.pCt.s.I....cGt....hhh......sh..hs.......th.hPpaCppCGpsaPWs.pp..tlpsh.clhp.hppLstp-ctthppsl.plh.-..sspT.lA.h+hKphht+.hut.hhsshpplllslso-ss+K...................................
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