GenomeNet

Database: Pfam
Entry: DUF2666
LinkDB: DUF2666
Original site: DUF2666 
#=GF ID   DUF2666
#=GF AC   PF10869.9
#=GF DE   Protein of unknown function (DUF2666) 
#=GF AU   Pollington J;0000-0002-8158-8998
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   PRODOM
#=GF GA   23.00 23.00;
#=GF TC   23.00 24.50;
#=GF NC   22.90 22.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR022620;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This Archaeal family of proteins has no known function.
#=GF SQ   19
#=GS A0A218NNJ7_9ARCH/6-135    AC A0A218NNJ7.1
#=GS Q5JGL5_THEKO/4-123        AC Q5JGL5.1
#=GS C6A0L1_THESM/138-263      AC C6A0L1.1
#=GS Q5JGL5_THEKO/138-262      AC Q5JGL5.1
#=GS A0A075LSG6_9EURY/4-129    AC A0A075LSG6.1
#=GS A6UU54_META3/2-136        AC A6UU54.1
#=GS Y596_METJA/2-136          AC Q58013.1
#=GS Q6M158_METMP/3-137        AC Q6M158.1
#=GS C6A0L1_THESM/4-124        AC C6A0L1.1
#=GS B6YU73_THEON/138-267      AC B6YU73.1
#=GS W0I6B1_9EURY/4-121        AC W0I6B1.1
#=GS F6BEN2_METIK/2-136        AC F6BEN2.1
#=GS Q8TZE5_PYRFU/134-251      AC Q8TZE5.1
#=GS Q8TZE5_PYRFU/134-251      DR PDB; 3V68 A; 134-249;
#=GS A0A075LSG6_9EURY/140-265  AC A0A075LSG6.1
#=GS D5VTM6_METIM/2-136        AC D5VTM6.1
#=GS D7DV69_METV3/3-137        AC D7DV69.1
#=GS B6YU73_THEON/4-123        AC B6YU73.1
#=GS W0I6B1_9EURY/138-263      AC W0I6B1.1
#=GS Q8TZE5_PYRFU/3-118        AC Q8TZE5.1
#=GS Q8TZE5_PYRFU/3-118        DR PDB; 3V68 A; 134-249;
A0A218NNJ7_9ARCH/6-135               .d-NYIDFS.....VKYNDWVAIKRLSIDDKVTPEEVVYNLASIESSIDSKVYKFL..G..IDINSIDSLAKNLAKQSG--SGYKGLPKLASLIDTKQVKDSLSKA..CKT.QVVV....PFA....KSYLLDKSLKYMKLSADIE-----------lptmlkaf.............
Q5JGL5_THEKO/4-123                   ..EEHVAFT.....AKHNDWRVAKKLT---ELEDENVAHFLAGIANSVNSRIPGYMgeK..IDIDGIRKLAEEVR---K-----DTLSDTIVALKSPGTSRKLGGL..VREnDKKL....KKL....LVDAAKAVLVRMTLEGV-------------vpinyp...............
C6A0L1_THESM/138-263                 .d-EHINFT.....AKNGSWIVVKRLIIDNKTPMADIARILASINETAVSKIPLYG..K..IDLDGIRKWFGDIKKARS----EAEIKTLVEKFFHIPVEN-----..YAP.NEFK....DHA....KIYALRVALEKVGLTIDIPAKPLEKYLEK-r....................
Q5JGL5_THEKO/138-262                 ..EDHVNFT.....AKHGKWIVVKRLIIDEKTPLLDVARLLASINETVTLKLPAYA..H..IDVEGIEGEFSAFKKVKK-----SDIPKVVEAYEAFEPSA-----..YAD.EPFL....EHA....RVYALRVALEKIGLPLDVPSKSLEKYLEKA.....................
A0A075LSG6_9EURY/4-129               ..EDHVMFT.....AKHGKWEVGEKLLVM---DDKHVAHFLARVSNTVNGKIGEYL..GniMNVPGIISLAEEIAEK-------DDPKEVFKALKSPSASRKLGKLvfETD.KKAK....KLV....VDVAKA------------------------flvretlvrakfkidypeepi
A6UU54_META3/2-136                   ..EQSIQFR.....AKKGKWTVIKKINIDENTTDTEVARLLNSIDETVNKKVYEFL..P..FDLDKIEEIANEIYEKKKGKVKEEDITNALLKLKSPATTRKLNAI..TKS.KEGK....AIV....KIILNNIVLERLGIKTRLETKLIDKYMEKN.....................
Y596_METJA/2-136                     ..EDKIEFM.....AKHKKWFVVKKLKIDENTEDIEIARLLASIDETVLNKIPEYL..P..FDMNKLYEIADGIYQKKKGRITEEEIAEVLKKLKSPATTRKLNEI..TES.KEGK....EIL....KAILNNIILERLGIQTRVSPKVIEKYIENS.....................
Q6M158_METMP/3-137                   ..EERIQFN.....AKKGKWYVSKKIKIDENTSNEEIARVLASIEETLSIKIKDFL..P..FDMEKLRAIADEIYEKKKGRVKEEDISGALTKLKSPGTTKKLGTI..DDT.KEGK....EIL....KRLLTEIVLERLGITSKIEAKMIEKYIEKS.....................
C6A0L1_THESM/4-124                   ..EDHIAFT.....ANHKNWKVGDKLLA---MDDRQIAHFLAMVSNTVTLKLPEYL..T..E-VMNVAGIMS---LAE--EMTEKDVWELLKTLKSPGTSRKLNPMifEEN.KKLK....NHLlnvaKALLTREALSK-------------------kvsinype.............
B6YU73_THEON/138-267                 ..EDHVNFTafhlsAEHGKWRVVKRLIIDEKTPMADVARLLASINETITLKLPVYA..G..IDVKGIDAWFAEFKKVKK-----ADIPAVVEKYKHFQAEN-----..YAR.EGFE....EHA....KVYALRKALEKIGLPLDVPAKNLEKYLEK-k....................
W0I6B1_9EURY/4-121                   ..EDHIMFT.....AKHKNWEVGDKLLIM---GEENIAHFLASVSNTVNTKISEYL..T..-DVMDVAAVMNLAEEMAKG-----ALWEVIKALKSPRASRNLGKLvfETD.KKLK....KHL....VEVSKA------------------------llvretlsrkiniy.......
F6BEN2_METIK/2-136                   ..ENRIQFI.....AKHNDWFVVKKMNIDDKTENIEIARLLSSIDETVLNKLPEYL..P..FDMKKLEEIADEIYQKKKGRVKEEDVVNALMKLKSPSTTKKLGEI..TDS.KEGK....EIL....KVILNNIILERLGIKTRVDPKLIEKYIEK-m....................
Q8TZE5_PYRFU/134-251                 ..EDHINFT.....ARYGSWIVVKRMIIDEKTPLLDIARLLASINETAVNKIKDFA..D..VDDKKIVEYFGGFKKVKK----EEEIKEIVQLFREF---------..---.-KGN....EFE....VRYAAREMLSKLGLKVDVPSKNLEKYLEKA.....................
#=GR Q8TZE5_PYRFU/134-251      SS    ..SSEEEEE.....EEETTEEEEEEEE--TTS-HHHHHHHHHHHHHHHHHHHHHHT..T..--HHHHHHHTTT--S--S----HHHHHHHHHHHHT----------..---.----....HHH....HHHHHHHHHHTTT--SS--HHHHHHHH-XX.....................
A0A075LSG6_9EURY/140-265             .s-EHINFT.....AKYGKWIVVKRLMIDDKTPMADIARILASINETATLKIAAYA..G..IDVKGISSYFKGISKKTK----GDELGIAVEKYLHFK-----GEN..YAP.EEFV....EHA....KVYALRIFLEKLGLNLDIPAKSLEKYLEK-k....................
D5VTM6_METIM/2-136                   ..EEKIEFL.....AKHKNWFVVKKLKIDENTEDIEIARLLASIDETVSRKFLEYL..P..FDLKKLEEIADQIYVKKKGRVKEEEIAEALKKLKSPAVSRKLNEI..TES.KEGK....EIL....KIILNNIILERLGIETRVPSRLIEKYIEK-e....................
D7DV69_METV3/3-137                   ..EEKITFN.....AKKGKWYVSKKLKIDEKTQDVEISRILISIEETLGKKIKDYL..P..FDMIQLEEIADEIYVSKKGRVKEEDISQALAKLKSPATTKKLGKL..TDL.KEGK....DIL....KVVLTNIILERLGIKTHIDVKTMDKFIEKS.....................
B6YU73_THEON/4-123                   ..EDQIIFT.....ARHGSWKVGDRLR---NMEDEMVAHFLASIANTVNPKIPEYL..T..-EVMNIAGIMSLAEEI-----ARKDLSDAVVALKSPGTARKLGALvfEED.KKLKkhlvEVA....KAILVREVLEK-------------------kvtvdyp..............
W0I6B1_9EURY/138-263                 ..EDHINFT.....AKHGSWIVVKRLIIDEKTPPADVARLLASINETITAKLPVYA..K..IDLKGIDDWFAEIKKAKS----DVEIKTVVDKYLHFPAYK-----..YAS.DEFI....EHA....KIYALRKMLEKIGLSIDIPAKPLEKYLEK-k....................
Q8TZE5_PYRFU/3-118                   er--ILEFT.....AKHEEWIVGENV---EDFTNENIAMFLSRVSNTVSSKIPGYLgeK..IDVNGLL-------SIKI----EGSLEEKLKALISPKVSRQIGRLvmEDD.KKLKkllvEVA....KAVLTREIL---------------------knelpief.............
#=GR Q8TZE5_PYRFU/3-118        SS    -S--EEEEE.....EEETTEEEEEE----SS--HHHHHHHHHHHHHHHHHHGGGG-TTT..B-HHHHH-------T--------SSHHHHHHHHTSHHHHHHHHTTB----.HHHHHHHHHHH....HHHHHHHHH---------------------TTTS--S-.............
#=GC SS_cons                         -SSSEEEEE.....EEETTEEEEEEEE--TTS-HHHHHHHHHHHHHHHHHHHHHHTTTT..B-HHHHHHHTTT--T--S----HCCHHHHHHHHCTHHHHHHHHTTB----.HHHHHHHHHHH....HHHHHHHHHHTTT--SS--HHHHHHHH---TTTS--S-.............
#=GC seq_cons                        ..E-+IpFT.....AKHscWhVsK+LhID-pTsst-lARlLASIsETlstKlscYL..s..hDlpslpplhstlhct+K....cc-lspslptLKSPsso+pLsth..pps.cchK....-hh....KshhtchhLE+lGlphcl.s+.h-KahEp.h....................
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