GenomeNet

Database: Pfam
Entry: DUF3196
LinkDB: DUF3196
Original site: DUF3196 
#=GF ID   DUF3196
#=GF AC   PF11428.9
#=GF DE   Protein of unknown function (DUF3196)
#=GF AU   Pollington J;0000-0002-8158-8998
#=GF SE   pdb_1td6
#=GF GA   26.70 26.70;
#=GF TC   27.00 27.00;
#=GF NC   26.50 26.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   15562512
#=GF RT   Crystal structure of the conserved hypothetical protein MPN330
#=GF RT   (GI: 1674200) from Mycoplasma pneumoniae.
#=GF RA   Das D, Oganesyan N, Yokota H, Pufan R, Kim R, Kim SH;
#=GF RL   Proteins. 2005;58:504-508.
#=GF DR   INTERPRO; IPR024503;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This proteins is the product of the gene MPN330 and is thought
#=GF CC   to involved in a cellular function that has yet to be
#=GF CC   characterised. The proteins has 11 helices and a novel fold [1].
#=GF CC   No function is currently known for this protein.
#=GF SQ   50
#=GS A0A1Y0L1X6_9MOLU/1-226    AC A0A1Y0L1X6.1
#=GS A0A174ZLQ9_CLOIN/1-95     AC A0A174ZLQ9.1
#=GS A0A084U2X7_MYCIO/1-242    AC A0A084U2X7.1
#=GS A0A2K9C9E2_9MOLU/1-245    AC A0A2K9C9E2.1
#=GS A0A396L3S2_9FIRM/1-216    AC A0A396L3S2.1
#=GS B7CDD5_9FIRM/1-233        AC B7CDD5.1
#=GS A0A3S0T804_9MOLU/3-244    AC A0A3S0T804.1
#=GS Q6F0U1_MESFL/1-218        AC Q6F0U1.1
#=GS A0A0B0HMC3_9BACI/7-173    AC A0A0B0HMC3.1
#=GS A0A291IRG4_9MOLU/11-256   AC A0A291IRG4.1
#=GS A0A0K1W256_9MOLU/1-238    AC A0A0K1W256.1
#=GS R5ZBX9_9FIRM/1-232        AC R5ZBX9.1
#=GS Q14P11_SPICI/3-249        AC Q14P11.1
#=GS Q8EUL9_MYCPE/1-264        AC Q8EUL9.1
#=GS Q9K8F2_BACHD/73-309       AC Q9K8F2.1
#=GS A0A221MBM8_9BACI/57-310   AC A0A221MBM8.1
#=GS Q9PQ65_UREPA/3-266        AC Q9PQ65.1
#=GS A0A2P6FBW5_9MOLU/2-244    AC A0A2P6FBW5.1
#=GS S5LTF0_9MOLU/1-238        AC S5LTF0.1
#=GS Q6MTH1_MYCMS/1-238        AC Q6MTH1.1
#=GS Y330_MYCPN/1-288          AC P75455.1
#=GS Y330_MYCPN/1-288          DR PDB; 1TD6 A; 5-288;
#=GS A0A1B3SJY8_9MOLU/1-245    AC A0A1B3SJY8.1
#=GS A0A2K8NRF7_9MOLU/1-225    AC A0A2K8NRF7.1
#=GS A0A380BXW7_SPOPA/175-316  AC A0A380BXW7.1
#=GS F2F0L3_SOLSS/66-321       AC F2F0L3.1
#=GS A0A3N0I349_9CLOT/1-226    AC A0A3N0I349.1
#=GS A0A0H3XHB8_9MOLU/2-246    AC A0A0H3XHB8.1
#=GS R6ZTJ0_9FIRM/1-222        AC R6ZTJ0.1
#=GS A0A3M8PB20_9BACL/86-317   AC A0A3M8PB20.1
#=GS S5LVZ7_9MOLU/1-245        AC S5LVZ7.1
#=GS W0GQH3_9MOLU/2-246        AC W0GQH3.1
#=GS A0A037UJZ8_SPIME/3-246    AC A0A037UJZ8.1
#=GS W6AGB3_9MOLU/2-236        AC W6AGB3.1
#=GS A0A0M0L789_9BACI/64-319   AC A0A0M0L789.1
#=GS A0A345Z387_9MOLU/1-240    AC A0A345Z387.1
#=GS R4UL42_9MOLU/2-234        AC R4UL42.1
#=GS A0A3P1SD01_9FIRM/3-226    AC A0A3P1SD01.1
#=GS V5RHM7_SPIAP/2-243        AC V5RHM7.1
#=GS A0A1G6HMD8_9BACI/60-318   AC A0A1G6HMD8.1
#=GS A0A2K8NZ29_9MOLU/1-240    AC A0A2K8NZ29.1
#=GS Y237_MYCGE/1-288          AC P47479.1
#=GS E7MPY7_9FIRM/1-228        AC E7MPY7.1
#=GS A0A265NEC0_9BACI/61-315   AC A0A265NEC0.1
#=GS A0A0K2JIZ7_SPIKU/3-245    AC A0A0K2JIZ7.1
#=GS Q7NBA7_MYCGA/6-290        AC Q7NBA7.2
#=GS M9WH75_9MOLU/1-243        AC M9WH75.1
#=GS B7GH23_ANOFW/117-297      AC B7GH23.1
#=GS H1BLR7_9FIRM/1-124        AC H1BLR7.1
#=GS A0A2K8NV39_9MOLU/1-238    AC A0A2K8NV39.1
#=GS D3FWD2_BACPE/64-327       AC D3FWD2.1
A0A1Y0L1X6_9MOLU/1-226               ..................................................................mad------------------------------------.----NYYETLLKDIQIFIDNQEYNNAAKLITNELAAPYIPG....D....I...EVKLYEYNQIINQHL................VNDLDDSM.LT...W.NVDKV.AQIMQ.QSLNQ..EMHLLAF.EALRG...LNARQ-.-.I.I.P.LIKTYLQDKAIKNEYKTF...LMMILIEQK--VDEDFLVYKNDNKIEIIFNPATFDVS--..ESQKFLADL.EMQ.LELL.VnS.K.N.PSLYTVCKNYASAYFYNVFP..I..FrLdQF.ELNDV.LAFIIMHSKK--..--------...----------------alglewe.........................................................................................................................
A0A174ZLQ9_CLOIN/1-95                ....................................................................m------------------------------------.---DTYYEDILKKVETLMKDAQFAEAYAILDEELSMPYIPReyeeP....L...IAYYNQCRSECKW--................--------.--...-.-----.-----.-----..-------.-----...------.-.-.-.-.------------------...---------------------------------------..---------.---.----.-.-.-.-.--------------------..-..-.-.--.-----.------------..--------...----------------kdtavreedietllkgsleeaflaieqlkksnirnhm...........................................................................................
A0A084U2X7_MYCIO/1-242               ...................................................................ms------------------------------------.-DIEKYYDEIIAKAEKLLEEKKYDDAIFLIEDELEAPYIPL....D....K...QTILEDLLLQTKADK...............sYFSGLYDV.EN...L.DRKQL.LNKVF.ENKKI..NPSALWL.FFERY...NSDLKD.N.E.I.D.FFEDILISKTVSNEDKNS...IFEMFICFG--IDKNFRYHNQNIGETFNINPIETSLF--..EQIELYANT.KKI.IDDL.A.S.K.E.PSLLNFCYNILTLIYKYYFP..S..I.P.NY.DYKEL.AKSIFGYMYNTL..RGEKIKDD...EITTLINKIL------q...............................................................................................................................
A0A2K9C9E2_9MOLU/1-245               ....................................................................m------------------------------------.----NFYDEIILEISELINNSDYHQAMTIISQELAMPYIPA....E....VelkLLQFKKQILNLSDGL................IKNSGAQT.FS...-.--IEN.IQKML.NN--E..NDIISQT.IAINN...IDKVNI.R.L.IvD.DIKKYLLNPKVASQNKTF...LLFALLKQD--FDMELEMFKN--SEHFTINPIELSVE--..KIDKEIQAI.KSI.VDQS.LgQ.E.N.PSLAEIATTSLFLYFFYSFP..K..V.A.LE.QTHEA.AAAII-YLAHEM..SG------...----------------ldykieettkwfkidlevtkqyiqqike....................................................................................................
A0A396L3S2_9FIRM/1-216               ....................................................................m------------------------------------.---DTYYEDILNKVEQLIAENDIQNAFCILEEELSMPYIPK....A....-...---YEDRLISLYNDCr..............sQINESRKA.RS...Y.GEEEI.GELLH.GSLEE..QFLAVEQ.L----...------.-.-.-.-.------------------...---------------------------------------..---------.---.----.-.-.-.-.--------------------..-..-.-.--.-----.------------..--------...----------------kksnirnhldeirsylkgnthyfvrsclieammeqniseefttemdglevtftpcfvempqesdgvekavsylqewfesdnptftmmcveslikeaylrlpftieedeafdlavdiacyvfkanedke
B7CDD5_9FIRM/1-233                   ...................................................................mn------------------------------------.----AYYHSLIKEIKKEIDEKSYAQAYELICQELNMPYVPQ....D....A...LELLESYKSECKP--................YLEQKN--.KS...M.DFNKL.HDYIH.GSLEQ..KIYAISM.L-ENM...NLRMCH.D.E.V.Q.----VLLDSDLPDEYKGT...LIEALMEQK--IDDPFDLIKSGL----NITFIPSAILPM..EQDLSICEA.SSL.FESW.F.TnE.D.PTMVQFCMSLLMQLVLYERP..F..D.Q.EDkDPYQL.AKSVTRLVYDAM..QK------...----------------sdewpsfvkkqglekiediel...........................................................................................................
A0A3S0T804_9MOLU/3-244               ..................................................................tpl------------------------------------.----NYYDELINEIKELISNHNYNGALIKINDELLMPYIPQ....Q....V...EKVLTTLLQEFNEKI................REQKPSET.TV...W.TLAKI.SDILA.NPSDEetQLLAFQY.LK--D...QNL--R.Q.I.L.P.VIRQYFMNKKVTDFAKIY...LLYLLKKQE--ITEIFEV--KKTNGIFHLNPSQII--PY..KENEQVKTI.MKL.LDQW.V.Y.NdN.PSLYHTCLYLLETYYYNLYP..Y..F.L.ENnEEKAL.TIAII-------..--------...----------------yqghrmygeeiviqdlaeqftvqveivkkyl.................................................................................................
Q6F0U1_MESFL/1-218                   ....................................................................m------------------------------------.----NFYDELIIELKELVLKNDFETALLKINQELSMPYVP-....-....-...-SDIEEQLLEFKTQI................FEQISKKA.NSnnnL.NAEYI.LQL-L.KSSDR..EQ---QA.FGINF...LNKINLrD.K.L.N.DVSELLTLEKIDNSIKTL...ILFTLKEQE--INKSFDVLYSGVQQSWNPIEIDFE----..NNFKFITEI.DEV.ISKS.I.E.NeN.PGIAHDAKMLN---------..-..-.-.--.-----.------------..--------...----------------infylnnldkfnnsflnekaaafiliaiemleekke............................................................................................
A0A0B0HMC3_9BACI/7-173               ..........................................eqrakqyeaifesdqwpkqlrtlhqld------------------------------------.-----------------------------------------....-....-...---------------................--------.--...-.-----.-----.-----..-------.-----...-SRIVP.H.L.V.S.IFSRYLHDEMKHPIVKTT...MLCILRKEQ--VMEPMTV--KKFGQTMTVVPAELD--EQ..IQKRWIEQV.LDI.VEQT.WaT.Q.N.PTMYEWCEQIWFRYMVVTYP..F..L.P.EG.SAQQW.ATALYTYVEQCE..TGKTVW--...----------------tnplvaklyea.....................................................................................................................
A0A291IRG4_9MOLU/11-256              ..............................................................rkgelkv------------------------------------.----NFYEERLLELQKLIDQNEIEQALKLINEELSMPYVP-....-....-...-KDFEDDLIKLRTRI...............lVEKINNEE.HH...L.SSDKI.FSLIK.SDQTD..LVEKVGL.VKQLE...ESNL-R.K.H.I.S.ELQDLLNSD-LTNEVKMM...IIYLLNQQG--INNDFNY--KKNSKTLKINPMTFDFQ-T..QEMVPLETI.KLI.DDEL.G.S.F.S.PQLVEMGKQIMVSLYGKLFP..I..Q.N.EI.DCAIL.AKAIIKIVYE--..--------...----------------lndlpynsnngldenkineykqmikdlevi..................................................................................................
A0A0K1W256_9MOLU/1-238               ...................................................................ms------------------------------------.----NYYEEVTKKLSTLIDKNNFDDALKIINEELLAPYIPE....K....F...EKYLLNWNNYIKEHI................QQNQNK-L.VS...W.SLERV.VNVMN.DVSDQqsHLIAFDF.L-REL...NARKII.E.D.I.K.--KYLIKSVNIDENKTFL...LMILIEQK-----IDMEFLVNKNKFSFSLNPAKFNVV--..ETQTLLKSI.ELQ.LEKT.I.Y.HyN.PSLYNIALSILNSYYYLKFPgfS..L.N.NF.NINDL.TISIIL------..--------...----------------kafksldvnpdpsiinsivhnhsnvml.....................................................................................................
R5ZBX9_9FIRM/1-232                   ....................................................................m------------------------------------.---NSYYQSLLQEIHKELDQKDYDKALRMIQTELDLPYVPR....E....E...LEVLQNYKSEC--LA................HIERPV--.VH...P.DLESL.IHGSL.QEQEK..AVALLQS.CNLRM...----MH.E.E.-.-.-VETLLCSSKLLDETKGE...LIESLMEQK--IEDPYKMK----KSGLEITFIPSIIVPS..SQDATIQEV.RDY.FDQW.F.AcD.N.PTFLRFCNRLLDQEVLENRP..L..D.F.EDcQALPI.AKALVRLVCEAF..G-------...----------------qdedfqtfckeknleeivevplr.........................................................................................................
Q14P11_SPICI/3-249                   ..................................................................tpl------------------------------------.----NYYDELIDEIKKLISNYDYNGAFVKINDELMMPYIPQ....Q....V...ETVLRRLLQEVNEKM................QEQKPRET.TV...W.TLAKI.SDILA.NPADEetQLLAFQY.LKDQ-...-NL--R.Q.I.L.P.VICKYFLNKKVTDFAKIY...LLYLLKKQE--ITEIFEV--KKTNGTFHLNPSQII--PY..KENEQVKTI.MKL.LDQW.V.Y.NdN.PSLYHTCLYLLETYYYNLYP..Y..F.L.ENnEEKAL.TVAII-YQGHRM..YGEQIVVQdlvEQFKVQVEIVK-----kylpyldq........................................................................................................................
Q8EUL9_MYCPE/1-264                   ............................................................mskkeaskk---------K--------------------QTEKPK.DQLTIYYENILSKVDALVKDKKINEALEMVNDELDSPYIP-....-....-...-SEFEEAFMTISYNLsa...........einYLNESVKY.ES...L.NREEL.FNSIL.NGKTI..NSVALSI.FLERY...KDNIEV.S.E.L.K.IFDSFLSSKKIFDIDKQN...LIIALKPLN--LDYEFDYYNSFADQIFKINIKSVNVL--..LSSPYFVEL.NKL.VEEF.T.Y.K.E.PSLQEFCYLIIFDLYVYYFP..N..H.P.DY.QISDL.AYAIFQYMLNSL..QGNIKEYKn.pEIIKDIEKIVGIFLR-a...............................................................................................................................
Q9K8F2_BACHD/73-309                  .........................................................gklddavlltdq--------------------------------MLRN.-DIGNYYDILQIHLSLLVQLGRYDEVVEMLDVVLAEDRLPA....K....H...AESFYQLLHF-SRQMved..........sptYIKEPL-S.EE...L.DLKET.YDDIN.ERDSL..EQWH---.FLQQM...RKHNNP.A.D.I.R.TLLSFVESESNDPALRSY...ALHMLTMHK--VEKRVRI--RKFDQEAEVIPVELN--AD..EQQRFGNAV.VEQ.LEAR.LaV.E.N.PSLFKMAEQLWWQFLYALYP..F..T.P.KP.EQKDL.------------..--------...----------------wagavhvavhesn...................................................................................................................
A0A221MBM8_9BACI/57-310              ...................................................lmeldryedaqvlseell-----------------------------------K.HRNENYYHYVHIYLTILFQTNQYKKLMEQVDYELDNVSVPQ....Q....M...KEQFQQLYDMSEK--................---MNVEI.KE...E.KHTEY.ISELL.EAVNE.qNHVKQWR.SVEKL...RKINTI.P.S.I.K.ATEALLTESFVHPVIKTA...IFKWLQDSE--CNENIRIH--KLEMQVEVKPNQVS--DI..HSHATFKQI.LLL.INKI.E.L.K.N.PTLYQLMETLLYRYIYVRYP..I..M.P.SSeHVKHI.AIAL--------..--------...----------------tnigeaylgmehlpdneldpdilryqd.....................................................................................................
Q9PQ65_UREPA/3-266                   .................................................................ciil--KIKKGMLKIMNNNK--------------------.SYIKKYFDDILIQAKQVLKKHDYAYAYDLISNEFNNPLIDL....K....T...LQEFEAFAIEIKKSAe.............lnFIDENE--.AK...L.AKTDF.YCKIH.DPKTTyvSLAYLET.FLMRF...INEMDE.L.D.I.T.FLNSLLTNKLINGSTKLD...ILDLLATNN--IDQNFNFYNKYLKQTKNVNPVNFN----..NHYQEIDQI.QNY.LNKY.L.A.K.N.PSLLHLANKLLMMYITYYFP..F..K.F.AH.NHNLI.AKTIIDYVKNAM..ENHVCQYS...EEQKAIVACINKILEE................................................................................................................................
A0A2P6FBW5_9MOLU/2-244               .................................................................stsl------------------------------------.----NYYDELINEIEELIDNSNYNDALTKLKTELTMPYIPQ....N....I...EKKLETLLKEVNAKM................LEQQPNPN.SV...W.TLAKI.SEILT.NPTDEetQLLAFHY.L--KD...QNLR--.K.I.L.P.VIRKYLVNKKVSNFAKIY...LLYLLKEQE--INEVFQV--QKTNGFFKLNPQEMTPY--..QEEEQVKLV.LQL.LDQW.V.Y.NdN.PSLYHTCLYLLETYYYDLYP..Q..F.I.VNnEIEAL.AVAII-YQGQVM..YNEKITIKv.lA---------------eqfdvalpivqkyl..................................................................................................................
S5LTF0_9MOLU/1-238                   ....................................................................m------------------------------------.---KNYYEELIKEIDLEIANKNFENALNLINEELNAPYIPV....E....F...ENYLNDKYIAILENT................-ENNNFIN.ER...W.NFDKI.LKSIS.QVEDQeiHLMAFDA.L--RT...MNIRKI.-.-.L.Q.NLKEYLLNEKIKPSNKSF...LLLILIEQS--I--NQEIFVNKNGNTISINPSNFDLM--..NSQKILKNI.ELK.LENL.V.Y.DtN.PSLFKISKHIANNYFYYVFP..NlnF.K.NY.SLNDL.CAAIIIKANEAL..--------...----------------gttlekeieekiifnkentml...........................................................................................................
Q6MTH1_MYCMS/1-238                   ...................................................................ma------------------------------------.----NYYDQILKKIKQLVEKNNLTKALDIINQELELSYIP-....-....-...-SDFEKSLYKIKKEI................KEKQY---.SQ...L.NKTYS.ILEIK.TLLNS..KNNLDQI.IGIKN...LININI.R.LvL.D.EIKKYLININNAYENKSL...LLISLSDQQ--IDQDFEVFKDK-KTSFLINPKSLNIK--..EIYNIYYQI.ESQ.ILEV.IdQ.K.D.IFLIQTCKQVLFSYFLYIFP..Y..V.E.LL.KTNDV.IVAII-YLSFQL..NNLKFDIK...KLNKNIE---------fnqvnvdkiii.....................................................................................................................
Y330_MYCPN/1-288                     .....................................................................MINKPNQFVNHLSALKKHFASYKELREAFNDYHKHNgDELTTFFLHQFDKVMELVKQKDFKTAQSRCEEELAAPYLPK....P....L...VSFFQSLLQLVNHDL................LEQQNAAL.AS...L.PAAKI.IELVL.QDYPN..KLNMIHY.LLPKT...KAFVKP.H.L.L.Q.RLQFVLTDSELLELKRFS...FFQALNQIPGFQGEQVEYFNSKLKQKFTLTLGEFEIAQQ.pDAKAYFEQL.ITQ.IQQL.F.L.K.E.PVNAEFANEIIDAFLVSYFP..L..H.P.PV.PLAQL.AAKIYEYVSQIV..LNEAVNLK..dELIKLIVHTLYEQLDR................................................................................................................................
#=GR Y330_MYCPN/1-288          SS    .....................................................................XXXX---SSTT-SB-----SSHHHHHHHHHHHHTTT-SSHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHTT-TTS-H....H....H...HHHHHHHHHHHHHHH................HHHH-GGG.GG...-.-HHHH.HHHHH.TTTTT..TGGGGGG.STTS-...TTSS-G.G.G.G.G.GTHHHHT-TTS-HHHHHH...HHHHHTT-GGGTT-EEEEEETTTTEEEEEETTSBSS---.HHHHHHHHHH.HHH.HHHH.T.S.S.-.HHHHHHHHHHHHHHHHHTTT..S..-.-.SS.-HHHH.HHHHHHHHHHHS..SS---TTS..HHHHHHHHHHTTT----................................................................................................................................
A0A1B3SJY8_9MOLU/1-245               ...................................................................mn------------------------------------.---DNYYDITLKKIHQLIDEEKYEEAYIIINQELSAPYVPM....D....F...EEKLQKLAIESSSKMq.............ndFVKNIN--.WN...L.DKVTE.IMKNN.LNLET..QLIAIDA.LR--N...LNVR--.K.I.I.P.HIKQYLANPEIKNEFKTF...MFFVLMEQK--IDEEFEVV--KFDSKYYINPCKFDLF--..ASQNVLKEI.ELK.LENL.I.YdK.D.PSLYTICKNVTSSYYYNAFP.dF..D.F.ETnTINDI.VTCILVYSQKAL..GLEV----...----------------nwdqisekiefnkrnvdkllnrf.........................................................................................................
A0A2K8NRF7_9MOLU/1-225               ....................................................................m------------------------------------.-----FYKDLEKKILALIANNEIEEASKLIEEELKMPYIP-....-....-...-QEFETFLLKMQKDI................FFKTRGEN.TS...L.EETSL.TIEAL.LNKLEsaKLTDQTW.AVINL...ENYNLR.P.H.L.K.ELETFLLRKNIPDDLKTM...LLMTLHQQQ--IPNLLQLWKN--NQVLKVVPSELKVT--..ELMDFFHETkLTI.MNHN.W.L.K.N.TTWEALSIKLALIFLLNYFP..K..T.L.DF.SVTDL.AAA---------..--------...----------------tdykalnllgesgnweilhs............................................................................................................
A0A380BXW7_SPOPA/175-316             sldgtdlhaiievledivesselspivvtfaltllhqaqysrqvtvrkfgfekevipatmalpgqdkrt------------------------------------.-----------------------------------------....-....-...---------------................--------.--...-.-----.-----.-----..-------.-----...------.-.-.-.-.------------------...---------------------------------------..------QAV.LAE.LEKL.L.I.Q.D.PSRLELAYGLVEKFMIIAYP..F..D.WgSY.SKEEI.ANAYIEYIDSLF..SGE-----...----------------elpntpllafikq...................................................................................................................
F2F0L3_SOLSS/66-321                  ....................................eeknyerakqvceellaigpnmyfevmelylti------------------------------------.----------------CMQLRQFKQVEKIIESLFDEQLIPE....Y....E...AEKFERLKNLNAHIA................ENQESHFQ.AT..iI.EDNEP.EEFTA.TEFSV..MSAQQQM.MLIHE...LTEKNI.R.P.Y.SgELKALIENETIQPFIKSL...LLILLVEQE--INMTVTV--TKLGQSKELNPVNFPLP--..TKLPQYTEI.TGF.ITEQ.L.A.Q.E.PSTLEFALHLIDKHAIVLYP..F..E.W.AGfSSEEV.AAGYIHYVKLMF..GE------...----------------esemnggivtflqni.................................................................................................................
A0A3N0I349_9CLOT/1-226               ...................................................................mn------------------------------------.----LYYQALIQEIHELMAQEKYDLALDKVQAELDLPYVPQ....P....E...LDVLEAYKEECL--T................HIDKP---.--...V.PHHEI.EVLIH.GNMEQ..QEAAVAM.--MGD...MNLWNM.H.D.-.-.EVQFLLDSDVLLNEIKGE...LIEHLMAQK--IDTPYTMKKSGLE----LTFVPSLIIPK..EDDQTLIQI.NQLfIDWF.A.N.D.N.PTFYQFCTRLLEQEMLENRP..F..D.F.MDqDPKPI.AKAIVRLVAEAF..--------...----------------gqsdefklfvtqkqlgei..............................................................................................................
A0A0H3XHB8_9MOLU/2-246               ..................................................................eks------------------------------------.---NNYYDEILTEIANLLKEGNYEAAYWKARNELEMPYIPQ....Q....V...ETKLVEFFKQANAVM................NEQTNRKLpAN...L.SLAEI.ENILL.NSLDEeiHLVAFHY.LK---...-NYNVR.Q.I.L.P.TIRKYLMNNLYHNASKIH...LLYVLKEQN--IDEDFQV--TKTNGTFTLNPTKIQ--DF..YTHHQVKKI.QKL.LDQH.V.Y.NdN.PSLFNVCLYILQNYYYALYP..S..F.I.DNnEVADL.TCAII-Y-----..--------...----------------kghllqfdnvqietiaeqlncsvaiankyle.................................................................................................
R6ZTJ0_9FIRM/1-222                   ...................................................................mn------------------------------------.----AYYLSLLKEIQKQIDDKSYQTAYDLIHQELELPYVPK....E....A...MEVLEEYQKECLSHM................----DRPV.RS...A.DDEQL.QAWIQ.GSLQQ..QEKAVSL.LQNLN...LRNY-H.D.E.-.-.-VQTLL-DSKLLDEYKGE...LIESLMEQK--IDDSYIVI----KNGLEITFIPSSIISK..DEDDVLIRA.REL.FDQW.F.SnN.N.PAFQNFCNRLLEQEVLEVRP..F..D.F.MDqDPYVL.AKAIVRLVLEAF..--------...----------------gqsdqlaafiqi....................................................................................................................
A0A3M8PB20_9BACL/86-317              ..........................................................pihyletmely------------------------------------.-------------ISILMQVRQYEEAEQMIEALIEENVLPE....E....R...LEQFRQLRD-LNEQI................VANASI--.ET...V.DSTMYqLEEFL.SLSPL.eQEWLIMD.LPPAS...YNALKK.H.L.L.A.IVG----HPEVDLLTKTY...ILFTLHQEN--IDAVVEVEKFHYQGRFRISELPDP----..LSNPRLESI.KKQ.IEES.L.S.K.D.PSRLELAKELFDRHVYLFYP..F..HwP.DF.PEAEV.AAAYMDYLDMLF..SGETS---...----------------aganerlleliiqa..................................................................................................................
S5LVZ7_9MOLU/1-245                   ....................................................................m------------------------------------.---KNYYEEIMDKINESINNNNFDEAFKIVLEELNAPYIP-....-....-...-NDFEKQLEKIQSQLae...........klnFNEKNS--.AN...W.NIDKV.LEIMS.KKLDQdvHLVAFDA.LR-GL...NARLI-.-.-.I.N.EIKQYLKDDEIKPEYKTF...LFMVLIEQA--IDEEI--IIKKINKEILLNPSKYNLN--..EAQEILKEI.ELK.IEKA.I.Y.DsN.PSLFTICQNIANTYFYYTFP..I.fE.FeKY.TLNDL.SVAIILKAQDS-..--------...----------------lglelnieqelkidfnkentmillnelnn...................................................................................................
W0GQH3_9MOLU/2-246                   ..................................................................kks------------------------------------.---NNYYDEILTEIANLLKEGDYEAVYWKARNELEMPYIPQqvetK....L...VEFFKQANTVMNEQ-................---TNRKLqAN...L.SLVEI.ENILL.NSLDEeiHLVAFHY.L----...KNYNAR.Q.I.L.P.TIRKYLMNSFYRNALKIH...LLYVLKEQN--IDEDFQV--TKTNGTFTLNPIKIQ--DF..YTHHQVKKI.QKL.LDQH.V.Y.NdN.PSLFNVCLYILQNYYYALYP..F..F.I.DNnEVADL.TCAII-------..--------...----------------ykghllqfddvqiitiaeqlncsvaiankyle................................................................................................
A0A037UJZ8_SPIME/3-246               ..................................................................tpl------------------------------------.----NYYDELIDEIKKLISNYDYNGAFVKINDELMMPYIPQ....Q....V...ETVLRRLLQEVNEKM................QEQKPRET.TV...W.TLAKI.SDILA.NPADEetQLLAFQY.LK--D...QNL--R.Q.I.L.P.VIRKYFLNKKVTDFAKIY...LLYLLKKQE--ITEIFEV--KKTNGTFHLNPSQII--PY..KENEQVKTI.MKL.LDQW.V.Y.NdN.PSLYHTCLYLLETYYYNLYP..Y..F.L.ENnEEKAL.TVAII-YQGHRM..YGEQIVVQdlaEQFKVQVEIVKK----ylpy............................................................................................................................
W6AGB3_9MOLU/2-236                   ...................................................................en------------------------------------.----NYYQEIIEKINNLIQEGEYEQAMNLVRDELNVPYVPF....D....F...ENQLEEISWKINGLL................SQNVDNSY.LN...W.NLDKV.SEIMT.QSLDQ..QLHLVAF.DALRG...LNA--R.K.L.L.D.QIKAYFLNVDIKNEYKTF...LLMVLIEQK--MDEIFEI--KKGDLTIRINPATFDL--K..ESQKFLKEL.EHI.LENA.I.Y.DiN.PSLHTVCIQVANTYYYNIFP..DfrM.P.DY.SINEI.AGAIAIYSQKAL..GLEI----...----------------ddeinqkinfnnd...................................................................................................................
A0A0M0L789_9BACI/64-319              .....................................................lgdiktakhhskrmlq------------------------------------.EGIGDYYQVLQIHLMILVQNGDYEEGATLLQAVFDEQQVPF....E....H...ASHLHNLLQFCQTRVe..............eLPDMPEPA.DE...H.DQDEE.LRLML.ENGNV..N-QQLDV.VQALY...QVDVNK.H.-.L.Q.LFEKMLKEESVHPIVKTM...LFKLLAEQQ--IDANIEVCKFTYKATF--NPSKMDMS--..ELDAFSAHV.QSR.LEEQ.LeS.N.D.PTLLSFALEIWQRYLFLLFP..F..Y.P.QQ.GEQNV.WVAAVHYAALEM..QGQEGEM-...----------------edvasqynlrlsa...................................................................................................................
A0A345Z387_9MOLU/1-240               ....................................................................m------------------------------------.--NKDFYDQTIIEIEGLIADKKYQEALEQINSELRMPYMP-....-....-...-ADFEAKLLKQQQEVg..............gLINQSNPN.PK...M.WNLEL.IKKML.NQVDE..NLQLNAI.EAL--...KGFNIR.A.I.L.P.ELKDFLINRNNCDENKVC...LIFIIADQH--INEEFKVVK--KNGTYNINPSQFNL--Q..DSLDNLKLI.REK.LLEI.V.YnD.N.PSLFNVCEFILNSYFYLAFP..N..F.A.QE.DLNSL.VAAIW-------..--------...----------------ykaslaqgveigyniveenikieeqkfnqmvd................................................................................................
R4UL42_9MOLU/2-234                   ...................................................................eq------------------------------------.---DNYYDELLSTIKTLIAQGEYHRAQEKINDELRMPYVP-....-....-...-AFVEKELKTLGKII................TVQIND-G.KR...I.DNVWT.PAKIT.AVLTQ..PLLSVDE.FLMVVpvlQAQNLR.N.F.L.P.IISELLVNPTVGDPIKVR...LLFLLQEQE--ITTPIKVI--KKKQTFTITPDTLK-WPYddDNHQKFLKL.FD-.--EI.V.YnD.N.PSLYHLCLNLLEAYYLYRFP..D..S.L.APsEIPVL.TTAIIT------..--------...----------------qankmlgvdydhhklvnrfai...........................................................................................................
A0A3P1SD01_9FIRM/3-226               ..............................................................ydfkgdy------------------------------------.---MNYYEEIIDRIKTLLKENKHQEASSLLKEELSMPYIPF....A....Y...QQELEALSASVETNY................------SM.SS...F.TDEEL.EEYLH.SSYDK..QLKAVTV.L----...----DK.L.N.L.R.HYQDMINRYLSHQPNRLVaslLIESLIMQN--IDYEVTYCIEDISYTFIPCFVEQP----..AQSDGYQKA.KSL.FDMY.L.N.H.N.PSLHKMAMDLLIQECMLSLP..I..T.Y.DEkEGEAI.GYYILQYLYKMF..HEE-----...----------------ealnelng........................................................................................................................
V5RHM7_SPIAP/2-243                   ...................................................................sa------------------------------------.----NFYDNLILMIEQNIKNRDFEKALELIKEELSVPYIPS....D....I...ESKLQNYLKDLESELs..............sKLNNDGSI.WT...L.NKISS.VMKQV.LDQEI..QLLAFDA.L-RSF...NARMIL.P.D.I.K.--DYLVSDLVKDEFKTFL...ILVLLEQK-----LDVDLVVKKGAKSFNINPATFDVS--..KFNQVINEV.DIK.LNNL.V.YdK.N.PTLFNICKHIAESYLYSIFP..N..FeFeGY.GINEI.LVCVIMTAKNSLgiNNELK---...----------------dfenidynyekamilln...............................................................................................................
A0A1G6HMD8_9BACI/60-318              .................................................velgrerdamamcedlidre------------------------------------.--DSDYYTYINIYATLLFQFHKHKEVKDLLEEALSHQDIPK....S....L...HNQLLKL-KEVNESL................VNEQVEQE.TV...M.THEKI.KEAVN.NEDTM..AQWHLVN.HLQRA...DL--SP.H.-.A.S.LLESMLVDGRVHPVVKTV...IVGLFQAES--IDRDVEV--SKFNQTIVINPVSHPFM--..NDHPFRHQL.KKM.LEAL.E.Q.E.D.PTLYRFSNQLIDRYFYVNYP..I..V.P.PEdELKSM.RDAVLAIVSQSL..GTDLSKFD..vENSEEVIEKMEMIL--ea..............................................................................................................................
A0A2K8NZ29_9MOLU/1-240               ....................................................................m------------------------------------.-----YYEKIKKEIEILIDENKNYEALELISEELKMPYIP-....-....-...-QEFENFLKLNKKKIt.............keLELNNKVE.SK...L.DVEDI.KNILL.NPVD-..--VWMQI.FVIKS...LENMNA.R.NlI.P.EISNFLSNENVFPENKTF...MLLMLSEQN--IDFQFNV--EKFGKNFKINPIDIKIN--..NFEKIIESI.KTI.TENT.IgN.D.N.PSLANVCLEYLTTYVLAIFP..K..F.I.NDsQINSLiAAGITK------..--------...----------------aniaygnnaklenlqqvikfdldlainffne.................................................................................................
Y237_MYCGE/1-288                     .....................................................................MINKPNQFLNHLDGLKQHFSDYDSLQKSFKKYLSENqTELNNFFFNQFEKIIVLVKKKEFKTAQERCEEELATPYFSK....P....L...VGFFQSLLQLINHDL................IEQKNQQL.AN...M.SCEKI.VEMVL.SDYPN..KLNLIHY.LLAKE...ASFVNP.N.L.L.Q.RMTFVLTDLELLELKRFS...FFKALNQIPAFKNHKVTYFNSKLKQKFVITLGEFAFPQT.dKTKQFFQQL.IKK.VSQL.F.L.K.E.PVSCEFAYEIIDALLVSFFP..L..H.P.NL.EVNHL.AKKIHQYVSKIV..INEVVDLK..dPTTKLIVDTLYEQLDR................................................................................................................................
E7MPY7_9FIRM/1-228                   .....................................................................------------------------------------.--MTNYYDEILTEIEDLIQHAKYGDANFLVQKELNMPYIPV....D....V...EQKLKSFKRELNYRL................SDEKEIRE.DS...L.D--SL.LRK-L.KGKPK.sQLAAASV.LVTRN...LRDC--.-.-.L.V.EIKDYLSKDPCPEAAAL-...LIEGLAEQE--ISDEFTLIKN----GVEYTFWSDDIVPV..HKSEGFLKA.QSY.LKDW.L.E.N.NhPDFYEMARTLLIHEVYVFLP..L..S.Y.DVdEAEDL.ALAMLKQVSDMM..DE------...----------------geiyqkvsnqlaya..................................................................................................................
A0A265NEC0_9BACI/61-315              ........................................................elgyyeeaqdice--------------------------------ELIQ.SKNQNYYHYVHMYLTILFQTNQFEQLMKQVEYEIENNAIPL....P....V...KEQFKQLYDMSEKMNy..............dLIAEKS--.-T...T.YLDEL.FQAIS.SQHFQ..EQWLITE.NLRKM...NAEPNE.E.V.I.A.----LLTSEDVHPVTKTS...IFQWLQDKN--YSKAVTVH--KLD--LHVSVKPDDIAKL..QSQPFIKET.LLM.ISGQ.E.Q.K.N.PTLYQLLEVLLFRYIYVRFP..I..M.P.PSeDVKQI.AAAL-SYIGETY..LNLHTISE..dEINKDYI---------eeiklcet........................................................................................................................
A0A0K2JIZ7_SPIKU/3-245               ..................................................................tpl------------------------------------.----NYYDELINEIKELISNHNYNGAIIKINDELLMPYIPQ....Q....I...DKVLTTLLQEVNEKI................REQKPNET.TV...W.TLSKI.SDILA.NPSDEetQLLAFQY.LKD--...QNL--R.Q.I.L.P.VIRQYFLNKKVTDFAKIY...LLYLLKKQE--ITEIFEV--KKTNGIFHLNPSQII--PY..KENKQVKTI.MKL.LDQW.V.Y.NdN.PSLYHTCLYLLETYYYNLYP..Y..F.L.EN.NDEEK.ALTI--------..--------...----------------aiiyqghgmygeeiviqdlakqftvqveivkkyl..............................................................................................
Q7NBA7_MYCGA/6-290                   .....................................................................IMKKWSNLIKTMMTKNKTFHTINEIINDLSNSELAN.DQNTQFYLSLLMMIKTDLDNKDFKKALTSIQEELDTDYLPL....A....L...IDYFKQAHLVTKRLM................YENEFDWL.EK...L.DKKEL.INKTI.INFPE..NLWYFDY.LATKE...ENFWNI.D.D.F.E.FFRHIFITKTYDNSDKLV...AAQLLQKIEPFINLSFEVYNNKLKQTFTVTLKKDDIWAK..NTQAYFNDV.LDQ.IESS.F.Y.K.D.PSKEQLATEIVNNIMQDYYP..S..Y.P.DFvSVKEL.ASGIIQYVKNCF..DNKKPNTK...-INSIVYDVIINCIDQ................................................................................................................................
M9WH75_9MOLU/1-243                   ....................................................................m------------------------------------.---KNFYDELLENINDAIDQKNYENALKLINNELSMPYIPT....D....V...EKKLLKLLKVIRNKQ................KEQLNLKT.ES...Y.DFYKI.KSLLNsDDYLQ..QLLA---.--FKH...LKTINI.KlL.L.D.DIKQFLIDKKNKNENKTL...LLMTLAELE--FDFDFKVIKN--KQ-YLINPVKIDFN--..YIDQKLLEI.EEL.ISKIiT.D.K.N.PSFIVMAKQVLYYFYFDNFP..D..V.K.LE.DVVEI.AIAVVDVVYQII..--------...----------------giksdlttlinhykfdhkkvkqlvntikk...................................................................................................
B7GH23_ANOFW/117-297                 ....................llqfsekmirsqyeqqakqyeiifeseqwskqlrilhqlhspivlrivp------------------------------------.-----------------------------------------....-....-...---------------................--------.--...-.-----.-----.-----..-------.-----...------.-.-.-.-.IFARYLCDETKHPIVKTT...MLHILKKEQ--VTEPITV--KKFAQTMTVVPAELD--EQ..KQNDWIEQV.LDI.VEQK.W.A.KqN.PTMYEWGKQIWLRYMFVMYP..F..L.P.TE.SVQQW.ANALYTYIEQCE..TGQTISTS...PLVS------------klykqk..........................................................................................................................
H1BLR7_9FIRM/1-124                   ....................................................................m------------------------------------.---DTYYEDILKKVEMQMEQHDHQAAYQILEEELSMPYIPK....EyeqrL...IDLYNACRSELQPQAqrsyseediemllkgsLEEQFL--.--...-.-----.-----.-----..-------.-----...------.-.-.-.-.------------------...---------------------------------------..---------.---.----.-.-.-.-.--------------------..-..-.-.--.-----.------------..--------...----------------aieqlrksnirnhldairdylgnaphylirsylieammeqni......................................................................................
A0A2K8NV39_9MOLU/1-238               ....................................................................m------------------------------------.-----FYEELKQELELLKQQKDFSAALKLIEQELQMPYVPH....E....F...EQYLINLKQEITSEM................MSEQTRNQ.KQ...Y.DVKEL.IKMLN.DEQDL..ASQAL--.-AIKA...LEHINV.R.PiL.T.EIEHYLMNAIMPDENKTL...ILFILNAQQ--INQSVKM--QKTNGFYTLNPMELQIN--..QFNQNFDQV.VLM.IENA.IgN.E.N.PSISQIACSSALIFMLINFP..A..P.N.QI.AANNL.AAAMIKQAHEFL..--------...----------------glelnypelktminfdqamveiil........................................................................................................
D3FWD2_BACPE/64-327                  .......................................................lvelgrleeavtht-------------------------------SALLN.EGIGEYYDNLQVHISLLVQLGHYQEVVDMLEAVLSENNVPA....Q....F...AESFYQLLHF-SRQMidds........vllaNIDDETMN.ES...QdDEQSV.IQEIS.NDLKS..GSIEIQWkALQVL...KDRPYK.D.A.L.E.VLVTYIEDSQKDWLLRSF...ALEILHTKN----YHAEVYIKKSTKEQKVIPSQLKAV--..NEQPFAVEV.KEA.LQDS.LeH.K.D.PLLKEMAEQIGGLHLFAWYP..F..I.P.TP.ENASL.WAAVYH------..--------...----------------llaserlgldesiseiadlyst..........................................................................................................
#=GC SS_cons                         .....................................................................XXXX---SSTT-SB-----SSHHHHHHHHHHHHTTT-SSHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHTT-TTS-H....H....H...HHHHHHHHHHHHHHH................HHHH-GGG.GG...-.-HHHH.HHHHH.TTTTT..TGGGGGG.STTS-...TTSS-G.G.G.G.G.GTHHHHT-TTS-HHHHHH...HHHHHTT-GGGTT-EEEEEETTTTEEEEEETTSBSS---.HHHHHHHHHH.HHH.HHHH.T.S.S.-.HHHHHHHHHHHHHHHHHTTT..S..-.-.SS.-HHHH.HHHHHHHHHHHS..SS---TTS..HHHHHHHHHHTTT----................................................................................................................................
#=GC seq_cons                        ..............................................................................................................sYY-pllpcIppLlpppcappAhphlppELshPYlP.....t....h....p.hpphhpphppph................h.ppst...ts...h.shpcl.hphhh.pshsp..p.hthph.hh.t.....sh..h.p...l....lpphLhspplps.hKhh...llhhLtcpp..Ispphpl..p+hptphplsPhphsh.....pppphhppl.pph.l-ph.l.h.c.N.PoLhphshplltpahh.haP..h..h...p..phppl.stAlh.h..p...............................tt...h..........................................................................................................................
//
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