#=GF ID   DUF3996
#=GF AC   PF13161.10
#=GF DE   Protein of unknown function (DUF3996)
#=GF AU   Aldam G;0000-0003-3039-8438
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF SE   Pfam-B_998 (release 24.0)
#=GF GA   22.00 22.00;
#=GF TC   22.00 22.00;
#=GF NC   21.90 21.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0193
#=GF DR   INTERPRO; IPR016489;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is functionally uncharacterised. This
#=GF CC   family of proteins is found in bacteria. Proteins in this family
#=GF CC   are typically between 172 and 203 amino acids in length.
#=GF SQ   19
#=GS A0A8J7UVQ5_9BACT/21-154   AC A0A8J7UVQ5.1
#=GS O51511_BORBU/22-169       AC O51511.2
#=GS O51510_BORBU/20-177       AC O51510.1
#=GS O51367_BORBU/47-200       AC O51367.1
#=GS A0A098QX61_9SPIO/19-154   AC A0A098QX61.1
#=GS F4GKC5_SPHCD/18-146       AC F4GKC5.1
#=GS W6TJ65_9SPIR/19-176       AC W6TJ65.1
#=GS W6TM79_9SPIR/37-205       AC W6TM79.1
#=GS O51366_BORBU/38-201       AC O51366.1
#=GS F5YR83_TREPZ/47-160       AC F5YR83.1
#=GS W6TIK4_9SPIR/106-259      AC W6TIK4.1
#=GS W6TMT2_9SPIR/18-169       AC W6TMT2.1
#=GS A0A1B6YEF1_9BACT/17-154   AC A0A1B6YEF1.1
#=GS A0A7Y6PST0_9DELT/32-186   AC A0A7Y6PST0.1
#=GS A0A1Y1S0P4_9SPIO/17-151   AC A0A1Y1S0P4.1
#=GS A0A081C6V0_9BACT/19-155   AC A0A081C6V0.1
#=GS O51512_BORBU/45-200       AC O51512.1
#=GS A0A1I4TJJ1_9FLAO/240-332  AC A0A1I4TJJ1.1
#=GS W6TIV6_9SPIR/19-166       AC W6TIV6.1
A0A8J7UVQ5_9BACT/21-154              ...............ass---QDYQRSRGIGVILGDP..TG---ISV.AY.RVSQ..SNafSGAAA--.........WHLRD.NPK..LHLHL......DY.LFYRFNILEVd...rgELP....LYFGAGGRLRFDS-------DNK---.................-..--LGVRFPLGIAYHFDNDpFELFLEIVPIL---EL------.....---.--------------vpetsftgnsgigiryyf....
O51511_BORBU/22-169                  .................n-SKESARGKFGAGIILPLP..IA---LQI.NI.GNFD..LD..IGLYSGV........nNLFSD.WKT..LFIAL......DY.IFYIYTFPGAan..ilDFS....VGAGGYGTIWFSRFGGSKSGSGP---.................-..MSIGARLPLALNIAVFRKkFDIFLRIAPGLGMNVWSNGV--.....---.GFRWEVFAGLGLRF......................
O51510_BORBU/20-177                  ..................TKDSYLNRGIGFGASIGNP..IINLIMSF.PF.IDFE..IG..YGGSNGInlsgpklesKFYDF.NLL..AIAAL......DF.IFTISLIK--......NLN....LGIGIGGNISISS----HTSKLINVE.................-..LGFGMRIPLVIFYDITEN.LEIGMKIAPSI---EFISNTRSlaqhrTYS.GIKSNFAGGIFAKY......................
O51367_BORBU/47-200                  .................i-KEKKNYDLFSMGIGIGDP..IANIMITI.PY.INID..FG..YGGFIGL.........KSNNF.ENY..LNGGI......DV.IFKKQIGQYM......KIG....GGIGIGADWSKTSLIPPNEEEETDYE.................R..IGAVIRIPFIMEYNFAKN.LSIGFKIYPAVGPTILLTKPSI.....LFE.GIKFNFFGFGFIKF......................
A0A098QX61_9SPIO/19-154              ...slsamglgvaaglpl--------------GNGLP..GNNVMLSL.KL.DNTPllFG..IGAQIG-.........--SNF.TSI..GVTA-......DYwITNESLAAPL......NFY....LGVGGYLGLSLGN-------STT---.................-..LSLGARIPVGLNIFILRS.LELFVEVAPALGVG--------.....---.--------------fsdpvqfpqvgvqgafgf....
F4GKC5_SPHCD/18-146                  ...............vfa------AEGLGLGISFGYP..AT--GVSF.SY.AQKD..FD..VIGTVGW.........NFSDNgYLA..AEAGV......NY.AWTSFNIDRA......KFD....VTAGLAGATWIPL----ND----NSQ.................K..LGLAVTVPVGIDYDFRDIpLEIFFRVSPGVQ----------.....---.--------------iipdtgfyiggtl.........
W6TJ65_9SPIR/19-176                  .................g-KSSYLDRKIGFGGSIGNP..IFNYIMSF.PF.IDIE..IG..YGGTNGIklpqsilksKKYDF.NIF..VLSAI......DL.IFTISLIE--......KLS....IGTGIGGNIHISS-NKSN---FKSME.................-..AGFGFRIPIAIFYDITEN.IEIGFKMAPSI---EFVSNPQSiayhyLYA.GFKINIIGGMFIKY......................
W6TM79_9SPIR/37-205                  .................q-KSSYPSNIFGIGFGIGNP..ITNIIINF.PY.VDVD..FG..YGGFNGL.........HPNNF.IPY..IVLGT......DI.VFKEEVYHNT......TLS....GGLGIGIDLSQVKPNEQDASNVTQQNnngqnkqeefsltssnnR..LGFTIRLPIILEYGFLKN.VFIGFKAITTIGATMIFNPTS-.....-ME.GIRFGFFGFGFIKI......................
O51366_BORBU/38-201                  .................a-KEESVRRLFGIGFGVGYP..LANITISV.PY.VDID..LG..YGGFVGL.........KPNNF.LPY..VVMGV......DL.LFKDEIHKNT......MIS....GGIGIGADWSKGSPEKSNEKLEEEEEneaqq......vaslqnR..IGVVIRLPLVIEYSFLKN.IVIGFKAVATIGTTMLLGSPMS.....-FE.GARFNFLGTGFIKI......................
F5YR83_TREPZ/47-160                  slklapvpvywsvnlkid-------------------..--------.--.----..--..-------.........---DD.IFG..IGLAG......DY.YFFDESLTGS.....sDFNlgwyLGAGIGAGISFGSWDG----YMGDYN.................HfgFNAAARLPIGLSAVFVKK.VEVFLGFVPALGFD--------.....---.--------------yasvtykpk.............
W6TIK4_9SPIR/106-259                 .................n-KKYKNAYSFAAGTGTGSP..LINLLISV.PY.VDID..FG..YGSFLYF.........NTINF.KPY..NLIAI......DL.IFRQLIGKSL......IIG....GGFGIGVDWSQANLTSPSSQKPSPYD.................R..IAIVTRLPLSIEYKIIKN.LSLGFKIYPTLGPTIFLTEPKI.....VFE.GMRFKFFAIGFIKM......................
W6TMT2_9SPIR/18-169                  .............akdey---TKNKGYFGIGILGPFP..SA---IQL.NLaKNIE..IE..FGFYNGL........kNLFQN.FNT..LFTSI......EFnIFSSNSFNKPk...piNTS....LGIGIYGLWWISKWQKTHEIYN--S-.................-..TNIGIKISLSLILPILKRhFDLFLKVGPGI--NIWGIGH--.....DYP.KHKWEVFAGLGIK-l.....................
A0A1B6YEF1_9BACT/17-154              .............tslka-----QNEGIAVGAQLFSP..TG-ITAKA.TI.SETA..-A..ITGVLGF.........NFNEF.NNI..INLQA......NL.ILSGNSDSFNve..sgVLR....PYYGVGVNFLFSE------NSD----.................-..TGIGFRIPLGMEYSLQDQpVELYMDIAPTVNVETSS-----.....---.--------------afflsssmglryff........
A0A7Y6PST0_9DELT/32-186              ...............gks---FEANKTFGLGLELGEPsgITGKYFLS.PS.GAVD..FG..LGYIYG-.........-HYYA.GDG..LHLYA......DY.LWHPLVLASAa...pfELP....FYVGLGGRFWSFDYGCDGNGRNCAYD.................G..SAFGVRVPLGLDLDFNNVpLDIFFQLVPTLDFY--------.....---.--------------rnyrdrdiylgidasigvrfwf
A0A1Y1S0P4_9SPIO/17-151              ...............paa------ASDIGAGIIIGEP..TG---LSF.SL.NN-Q..FV..LG-----.........AAWSF.REY..VHLHG......DY.IFLRNGIEKIeeeiakPFG....WYLGGGAKVRIFT-----RDKDTDDS.................A..VGLGLRIPVGVTFYPAEK.IELFLELAPGIA----------.....---.--------------lfpdtegdldggigiryhf...
A0A081C6V0_9BACT/19-155              .............nqafa-----QRQGVGLGVILGEP..TG---LSLkSW.MSTS..TA..L---NLA.........AAWSF.EKYgaFQVHL......DY.VFHHPRLVEP......NLP....FYYGLGGRIKLKD-----TGNDENEA.................R..LG--VRLPLGLVYLFREApLDFFVEIVPVLDV---------.....---.--------------apdtsvnlnaalgmrfyf....
O51512_BORBU/45-200                  .................i-ESLKAKTKIKFGFILPYP..TA---IEF.SI.NNFD..IG..VGVTIL-.........SVSEF.FPK..SPIALlfkiycDY.IFLNLKFKDS......NFI....FFLGSSLFFEIGK---ITSSDLTNVSsg............ityK..IGVG--LPLGIIYEAYYDiIEIIIKTTPSIFIGQMPNGNLIfpikgNFSiGIKGS---------lk....................
A0A1I4TJJ1_9FLAO/240-332             ........nigifsnysh-------------------..--------.KF.YNLD..IV..YAGLLDM.........KINNF.MST..Q-LTI......NL.IYDEDQVKQT......QFK....QALGIGLTYKIDSTKKNEKKRKR---.................-..------------------.----------------------.....---.--------------kkeilpyfdtshvypvii....
W6TIV6_9SPIR/19-166                  ...............fan---STARSNFGIGILLPFP..IA---LEL.NI.ENFD..ID..LGIYNGA........nNLFQN.WQT..LFLAI......DY.IFYMHTFKELnq..mlNFS....IGGGGYGTIWFSRWNHTHTNSGP---.................-..ISIGARLPLILNLAIFIKkFDVFLKVAPGLGINIWNGGA--.....---.GFRWEIFAALGIRY......................
#=GC seq_cons                        .................s......ppthGhGhhlG.P..hs...lph.sh.hsh-..hs..hGsh.Gh.........ph.sF.h.h..lhlul......Da.IFppphhpps......phs....huhGlGushphss....pptptp..t....................huhuhRlPlulpashhcp.l-lhhclsPsls.......................................................
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