GenomeNet

Database: Pfam
Entry: DUF4453
LinkDB: DUF4453
Original site: DUF4453 
#=GF ID   DUF4453
#=GF AC   PF14627.7
#=GF DE   Domain of unknown function (DUF4453)
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:C9CWS7
#=GF GA   26.10 26.10;
#=GF TC   26.10 32.60;
#=GF NC   25.80 20.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR027920;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This short domain is found only on a small subgroup of proteins
#=GF CC   from Gram-negative Proteobacteria that also carry a YARHG
#=GF CC   domain, Pfam:PF13308. They carry three conserved tryptophan and
#=GF CC   three conserved cysteine residues.
#=GF SQ   33
#=GS A0A372IE74_9RHOB/82-192  AC A0A372IE74.1
#=GS A0A238LB25_9RHOB/82-186  AC A0A238LB25.1
#=GS A0A1I6YHE4_9RHOB/72-177  AC A0A1I6YHE4.1
#=GS A0A1D9MAN0_9RHOB/63-164  AC A0A1D9MAN0.1
#=GS A0A2R8A7Q6_9RHOB/81-193  AC A0A2R8A7Q6.1
#=GS A0A1B0ZNG3_9RHOB/80-189  AC A0A1B0ZNG3.1
#=GS A0A2G5K4W4_9RHOB/81-189  AC A0A2G5K4W4.1
#=GS A0A239EA46_9RHOB/88-197  AC A0A239EA46.1
#=GS Q5LP49_RUEPO/80-185      AC Q5LP49.1
#=GS A0A2T0RTJ8_9RHOB/80-186  AC A0A2T0RTJ8.1
#=GS K2JD26_9RHOB/84-194      AC K2JD26.1
#=GS A0A347UDG6_9RHOB/89-195  AC A0A347UDG6.1
#=GS A0A1H5WIU7_9RHOB/75-181  AC A0A1H5WIU7.1
#=GS A0A3L9Y4H9_9RHOB/37-134  AC A0A3L9Y4H9.1
#=GS A0A316G5J8_9RHOB/80-185  AC A0A316G5J8.1
#=GS A0A1X7NUX8_9RHOB/81-189  AC A0A1X7NUX8.1
#=GS A0A2T0RZ87_9RHOB/89-195  AC A0A2T0RZ87.1
#=GS A0A0J9EBP0_9RHOB/64-169  AC A0A0J9EBP0.1
#=GS A3VM20_9RHOB/56-163      AC A3VM20.1
#=GS A0A0P1ERS7_9RHOB/78-180  AC A0A0P1ERS7.1
#=GS A0A1N6IC67_9RHOB/77-186  AC A0A1N6IC67.1
#=GS A0A0P1GLR8_9RHOB/78-180  AC A0A0P1GLR8.1
#=GS A0A2T6K7Z3_9RHOB/83-189  AC A0A2T6K7Z3.1
#=GS A0A1X4ITM9_9RHOB/89-192  AC A0A1X4ITM9.1
#=GS I7EYE6_PHAIB/81-187      AC I7EYE6.1
#=GS Q1GN31_RUEST/100-202     AC Q1GN31.1
#=GS A0A2R8BGY1_9RHOB/80-186  AC A0A2R8BGY1.1
#=GS A0A369QWD2_9RHOB/90-195  AC A0A369QWD2.1
#=GS Q28KG3_JANSC/83-195      AC Q28KG3.1
#=GS A0A0B4EJS0_9RHOB/79-185  AC A0A0B4EJS0.1
#=GS A0A347UJG2_9RHOB/81-191  AC A0A347UJG2.1
#=GS A0A073J2A0_9RHOB/78-182  AC A0A073J2A0.1
#=GS Q1GFK8_RUEST/80-186      AC Q1GFK8.1
A0A372IE74_9RHOB/82-192             .............GCDMDTGVRRL.qTMSELEDL.RRFAVLPVP..VDGAYGCIGYL.GPDLPLYTAPGAtHGPVMGTIRRGSSILFEYM..PE.....AGWDFVTAY..A..TG.W.KgpP.SASGWL..DMR..N.G..EPD.CEDYAG...........
A0A238LB25_9RHOB/82-186             .............NCRVDTTRTEL..DVPHLATR.LALIDLPVW..GLGESACLGWR.GPPLILRSGRSD.SAPMTGVIETGENILLMYA..DV.....DGWSFVPSP..D..GD.A.R..M.---GWV..RLP..R.L.dATS.CDGLAG...........
A0A1I6YHE4_9RHOB/72-177             .............GCRVDTNRTWL..DLPDINFR.KVLTSLPVL..DELPGKCIGWS.GPETPLYAGHQE.PFQVIGKIMPGDDVGYNHL..SV.....ADWTYVTTH..V..PY.G.E.aM.KSAGWV..YAP..-.N..GSS.CTDF--i..........
A0A1D9MAN0_9RHOB/63-164             .............GCAVETSQTGF..ELPTEAAL.RAAEELPVP..SPGESLCLGFN.APTVPLRAAPRL.EAEVISSVMAGDAVGFGYE..PV.....AGWDYVVTA..-..--.-.-..-.RGGGWM..PGD..T.I.gPES.CEGWAG...........
A0A2R8A7Q6_9RHOB/81-193             ............q-CAVDTEAQGL..DLPDLPWR.RTMIDLPVA..DGAESGCLGWR.GGRALLHAGAGA.FSRVTGSIEPGDVIISAHE..AIesnagGRWIYVTVHprT..AA.A.D..P.VSAGWT..DEA..-.I..FSD.CSSVAG...........
A0A1B0ZNG3_9RHOB/80-189             .............SCRVNTKQHHL..DLDDLHIR.RLLSDLPIP..DEIQGACLGWM.GPATALHAGHSE.ASPVIGQILPDDTVSYSHW..PD.....AGWTYVTTS..AghGD.W.R..V.KSGGWL..NYE..K.A..GEVpCRDFAG...........
A0A2G5K4W4_9RHOB/81-189             ............e-CAVDQSQTSI..SVYNQASR.LRLLTQPIA.tEDNVKVCFGAQpDKPIVLHKDKTE.TSPVLAVIDTGDTLGWLHL..NE.....GDWQFITLM..S..KS.K.P.gK.ISSGWT..DQA..-.G..NLQ.CDEIAG...........
A0A239EA46_9RHOB/88-197             .............GCKVDTGSTYL..ELPLMEHY.RRLSDMPLP..DNGASACLNWI.GPSVPLLSGYAG.GARHLATIERGDRIGFGYI..PE.....GSWVAVVLS..K.gGA.G.G..R.EVLGWF..DSGplN.L..ESA.CSDWAG...........
Q5LP49_RUEPO/80-185                 .............GCRVNTGQTWL..DLDDVFWR.RQLWVLPVR..DEFESACLGWL.GPVIALRAGPGH.GTAQIGQILPGDTVGYAHI..PV.....DGWTYVTAH..A..PD.W.Q..V.KSGGWL..DLS..-.I..PEQ.CRDFAG...........
A0A2T0RTJ8_9RHOB/80-186             .............ECSVDTKSTWL..DLADIEQR.ARFLTLPVR..GDGESGCMGWR.GGVLQLHQGKRF.DTPVTGRIVPGDHIGFSYM..PE.....GNWEFVIVR..R..PS.T.G..E.AFMGWS..QVP..Y.S..EDG.CDQWAG...........
K2JD26_9RHOB/84-194                 .............GCTLNTQSTYL..ALDDIQFR.RLLVEQPTLfpEGEGFLCMGYT.GYGVSLLAGPES.NSGVISALEPGDWYRTRHD..DI.....GAWTYIIVT..A..PHsE.R..V.KAAGWAmfAPD..-.S..YMQ.CLAAA-g..........
A0A347UDG6_9RHOB/89-195             .............ACNIDTGQQKL..DLPDLELR.KQLDFQPAT..DGGTGVCFGYT.GPEQPLFAAPWE.NARTIGVIHQGDDITIAHL..DW.....HGWGFTTVM..-..QG.N.E..T.KALGWY..KIP..VaD..PAQ.CRVFAG...........
A0A1H5WIU7_9RHOB/75-181             .............GCRVDTSRRWL..DLPDIAFR.RVLQDLPIP..DELGWGCLGWT.GPVTPLYSGHRG.PFHAIGQVTAGDYVSFSHL..PV.....GDWAYVQVH..A..PV.WgP..F.KSAGWL..YW-..-.-..---.------pgpvpcaaeag
A0A3L9Y4H9_9RHOB/37-134             aaqvsegpaftlg-----------..--------.-LLTVLPTP..AGTERTCTGYL.GQTVQLRAAPND.EADAVGSVMEGDRVVFAHE..PL.....DDWHYVTVT..S..GQ.G.V..IpQSDGWL..HL-..-.-..---.------pdgidcaet..
A0A316G5J8_9RHOB/80-185             ............t-CQVDTSRPAL..DLDDLAVR.QRLVDLPVR..DLTDSLCLGWN.GPETPLRAGRSD.AAEALGAIATADVVRFAHW..EE.....EGWQYVTVF..N..SD.L.S..V.KAGGWL..APG..-.L..DAN.CTAYAG...........
A0A1X7NUX8_9RHOB/81-189             ............e-CAVDTSATSL..DIANIPLR.LKLDSVVAL..SEFASGCLGWT.GEAIPLRAGPQD.EAEVISVAMPGDDLVWEYE..GTn..wpEGWSFLTVY..-..RD.E.A..Q.VSLGFA..RDD..L.D..YDL.CTGLAG...........
A0A2T0RZ87_9RHOB/89-195             .............GCKVNTGGTSL..DVPMKSNL.LRLRDMPLP..ADGGWGCLGWA.GRAAPIHDGYSS.GRRVIGSIDPGDNVFFGFL..GE.....GGWSPVIVA..K.gGN.G.G..K.EILGWI..DAS..-.L..DPV.CTSEAG...........
A0A0J9EBP0_9RHOB/64-169             .............GCRVDTSAGRV..SVSLSEAR.KRLTDQPFP..SIYESACIGWR.GGPLSLFAGRGQ.DAAKMATVFDGVDLLLQYE..DA.....DGYSFVEAM..-..TE.G.E..V.VAVGWA..AIR..F.D..AAS.CEMMAG...........
A3VM20_9RHOB/56-163                 .............GCKVDTAAERI..DMPNDYMF.RKLEDLPAP..SETGSACMGWR.GPEIAVLAGHRM.DAPVVGTVRPGMDIMWDYE..SFg...pAGWEIVSVY..E.gSD.W.-..-.VGLGWV..EGP..I.D..PGH.CTQLAG...........
A0A0P1ERS7_9RHOB/78-180             .............SCKINTKDRRL..-AASLIGKlEDVDLLPTL..SEFESSCVGYT.GAPVTMTSGIGMrDSYPTGIIASGETVHFRFE..PW.....GGFEFVETD..-..--.-.-..-.SGAGWV.pEGS..I.T..PNT.CEVFAG...........
A0A1N6IC67_9RHOB/77-186             .............GCVVDSNRTSL..DIPDLDIR.RRLAVLPIR..SDGESGCIGWK.GGPVALRTGTSQ.AAEPLFTLAPGDVVLFSHEvePAg...gQTWDYVQVY..D..-E.G.V..L.LKAGWT..VIE..V.S..PAT.CEGLAG...........
A0A0P1GLR8_9RHOB/78-180             .............SCNINTKGRHL..-ASSLIGKlEDIDLLPTL..SEFESSCVGYT.GAPVTMTSGIGMrNSYPTGSITGGETVHFRFE..PW.....GGFEFVETD..-..--.-.-..-.SGTGWV.pEGA..I.T..PNS.CEVFAG...........
A0A2T6K7Z3_9RHOB/83-189             ............q-CATDTSETRL..DLEGVVDL.RRLQDLPVR..AGTQIGCVGWR.GGRVPLLAGNSD.DAPEIGQIVRGDAIGFLHE..SE.....DEWDFLTVF..W..GP.G.D..-.GQFGWT.rEDT..R.K..PEN.CAQITG...........
A0A1X4ITM9_9RHOB/89-192             .............GCKVNTGQTWL..DVPNMDGL.RRLRDMALP..DNGASACT-WA.GAPLPYYDGYSA.GAQVIGQINVGDRIGFGWI..GE.....GDWTVIAVG..-..--.-.G..Q.SVIGWVnfSNS..N.F..EQS.CADWAG...........
I7EYE6_PHAIB/81-187                 .............GCKVNTKRRQL..TLNDTHLR.RLLVNLPIR..DEFESACLGWL.GAPVPLYSGHSA.GTARIGLIQPGDVIGYSHL..PV.....GSWSYVTTH..T..SD.W.R..V.KSGGWY..DRS..A.A..PEQ.CRDFAG...........
Q1GN31_RUEST/100-202                .............SCKINTKGRHL..-ASSLVGKlDDIDLLPTL..SQFESSCVGYT.GAPVTLTSGIGMrDSYPTGTIQGGATVHFRFE..PW.....GGFEFVETE..-..--.-.-..-.TGAGWI.pEGS..V.T..PDV.CTAFAG...........
A0A2R8BGY1_9RHOB/80-186             ............q-CSVDTKSPYL..DLDDAWVR.RQLATLPIV..DDFESACLGWL.HTPEPLRSAAYD.DAPIIATILPGDNVSFGHL..PN.....RTWDYVTIS..G..PD.W.V..V.KGGGWL..KAP..G.A..EGR.CANYAG...........
A0A369QWD2_9RHOB/90-195             .............GCRVDTAATTL..DVTGMAQL.RRLVDMPLP..DNGGSACT-WA.GPEAVLHAGKGP.GTAALGRLTAGDRVGFGWI..GE.....GDWTVISAS..-..-S.G.G..P.SILGWI..DVR..A.LhfERN.CTDWAG...........
Q28KG3_JANSC/83-195                 .............NCQVDTQAGQLsgDVEPFRTRlRELVTIPVR..GDSEHGCRGYG.GPPVALHAGTSP.STTVIGTLVAAQGFSVSHI..TM....rSGWEYLEVY..D..PD.G.P..V.VAHGWTrnDLE..T.M..VAS.CTFFAG...........
A0A0B4EJS0_9RHOB/79-185             .............GCRVNNKQTHL..DMDDLFLR.YQLWDLPVR..DEFESACLGWL.GPVMGLRAGHRP.DAPLVGQIDPGDYVNYSHI..PV.....GSWTYVTTS..G..PD.W.Q..V.TSGGWL..DTS..L.F..QEQ.CQDYAG...........
A0A347UJG2_9RHOB/81-191             .............ECHVDNQRQHL..DVDLIEQR.KQMLDLPYA..TEFESACVGWL.GPALPIHNARHV.DSHVIGHLQKGDQIDFFHE..IMvdeagNDWFFITQR..-..RN.N.R..V.VGVGWV..FFG..D.D..LDK.CEMFAG...........
A0A073J2A0_9RHOB/78-182             .............GCKVDTTSRRI..ELEDLALR.RQLTVQPVL..DEFPSGCVGWT.GGQIRLHAGTST.ATQVIGSAQTGDNIYFSHS..PQ.....NGFSYVTVT..D..SA.F.V..A.KSGGWL..RDG..F.D..PAL.CTQ---n..........
Q1GFK8_RUEST/80-186                 .............GCRVDTSRSRL..DVLDLRYR.QRLVDLPVT..DGLESTCIGWR.GDPLPLRAGHGL.NTDVIGQVLPGDTLNYGHY..PV.....GGWSYVTVH..D..SD.W.H..L.KSAGWY..RVD..A.Y..PQR.CAQFAG...........
#=GC seq_cons                       .............uCpVDTspspL..DlsslthR.+pLssLPlh..sphpSuClGWp.GsslsLpuGtut.sutslGsItsGDslsaua...sh.....uuWsaVsst..t..ss.h.t..h.pusGWh..chs..h.h..ssp.CpsaAG...........
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