GenomeNet

Database: Pfam
Entry: DUF4689
LinkDB: DUF4689
Original site: DUF4689 
#=GF ID   DUF4689
#=GF AC   PF15755.7
#=GF DE   Domain of unknown function (DUF4689)
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   Jackhmmer:Q6UWD8
#=GF GA   27.00 27.00;
#=GF TC   33.00 33.00;
#=GF NC   25.30 24.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR031499;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is found in eukaryotes. Proteins in this
#=GF CC   family are typically between 202 and 224 amino acids in length.
#=GF SQ   73
#=GS G3I4J4_CRIGR/1-201        AC G3I4J4.1
#=GS H2QAV2_PANTR/1-223        AC H2QAV2.1
#=GS A0A4W2DMJ4_BOBOX/1-217    AC A0A4W2DMJ4.1
#=GS A5PKB9_BOVIN/1-217        AC A5PKB9.1
#=GS L5MJD6_MYODS/1-93         AC L5MJD6.1
#=GS A0A5J5MPB7_MUNRE/1-217    AC A0A5J5MPB7.1
#=GS L8IXN7_9CETA/102-192      AC L8IXN7.1
#=GS H0XZE3_OTOGA/1-225        AC H0XZE3.1
#=GS G3QX39_GORGO/1-223        AC G3QX39.2
#=GS A0A673TZU1_SURSU/1-223    AC A0A673TZU1.1
#=GS CP054_RAT/1-224           AC Q5BK39.1
#=GS A0A1U7UAT5_CARSF/1-221    AC A0A1U7UAT5.1
#=GS A0A2Y9EST6_PHYMC/1-223    AC A0A2Y9EST6.1
#=GS A0A484GT94_SOUCH/1-223    AC A0A484GT94.1
#=GS W5P637_SHEEP/4-117        AC W5P637.1
#=GS CP054_HUMAN/1-223         AC Q6UWD8.1
#=GS A0A2R8MFT0_CALJA/1-223    AC A0A2R8MFT0.1
#=GS H2NRX5_PONAB/1-223        AC H2NRX5.1
#=GS A0A384BLZ5_URSMA/98-148   AC A0A384BLZ5.1
#=GS A0A2F0B698_ESCRO/31-253   AC A0A2F0B698.1
#=GS A0A4X2KS28_VOMUR/38-253   AC A0A4X2KS28.1
#=GS A0A2U3Y2X2_LEPWE/1-223    AC A0A2U3Y2X2.1
#=GS A0A1S3AJX4_ERIEU/1-217    AC A0A1S3AJX4.1
#=GS A0A1A6GCH5_NEOLE/1-131    AC A0A1A6GCH5.1
#=GS A0A341BBP8_NEOAA/1-223    AC A0A341BBP8.1
#=GS A0A384AGV1_BALAS/1-223    AC A0A384AGV1.1
#=GS A0A286XQI6_CAVPO/18-240   AC A0A286XQI6.1
#=GS A0A340X1A2_LIPVE/1-223    AC A0A340X1A2.1
#=GS CP054_MOUSE/1-224         AC Q8C708.1
#=GS A0A5E4C763_MARMO/1-224    AC A0A5E4C763.1
#=GS A0A5G2QHF6_PIG/1-202      AC A0A5G2QHF6.1
#=GS A0A3Q7WEU0_URSAR/1-223    AC A0A3Q7WEU0.1
#=GS J9P8N4_CANLF/150-281      AC J9P8N4.2
#=GS V8PF27_OPHHA/379-491      AC V8PF27.1
#=GS A0A5N4CVY4_CAMDR/317-533  AC A0A5N4CVY4.1
#=GS A0A671FDJ2_RHIFE/1-223    AC A0A671FDJ2.1
#=GS G1QCE9_MYOLU/1-226        AC G1QCE9.1
#=GS L9KUH4_TUPCH/1-216        AC L9KUH4.1
#=GS L8IXN7_9CETA/1-106        AC L8IXN7.1
#=GS A0A1S3ER18_DIPOR/1-218    AC A0A1S3ER18.1
#=GS T0NR12_CAMFR/107-322      AC T0NR12.1
#=GS A0A0D9SBY8_CHLSB/1-223    AC A0A0D9SBY8.1
#=GS A0A2U4A9F6_TURTR/1-223    AC A0A2U4A9F6.1
#=GS A0A2Y9L806_ENHLU/1-229    AC A0A2Y9L806.1
#=GS A0A2Y9PAN9_DELLE/1-223    AC A0A2Y9PAN9.1
#=GS L5KJM5_PTEAL/1-223        AC L5KJM5.1
#=GS M3WH47_FELCA/1-211        AC M3WH47.2
#=GS G3W526_SARHA/1-213        AC G3W526.1
#=GS A0A643C520_BALPH/1-34     AC A0A643C520.1
#=GS A0A402FPY3_9SAUR/2-78     AC A0A402FPY3.1
#=GS A0A4U1FLC5_MONMO/1-223    AC A0A4U1FLC5.1
#=GS A0A6G1B353_CROCR/1-223    AC A0A6G1B353.1
#=GS A0A384BLZ5_URSMA/1-101    AC A0A384BLZ5.1
#=GS A0A2U3VQB7_ODORO/1-223    AC A0A2U3VQB7.1
#=GS A0A2K5XKG2_MANLE/31-216   AC A0A2K5XKG2.1
#=GS L5MIA8_MYODS/1-202        AC L5MIA8.1
#=GS A0A2K6DDL4_MACNE/1-223    AC A0A2K6DDL4.1
#=GS A0A1U7QBZ5_MESAU/1-221    AC A0A1U7QBZ5.1
#=GS G3TX68_LOXAF/1-223        AC G3TX68.1
#=GS A0A2Y9E5D7_TRIMA/1-223    AC A0A2Y9E5D7.1
#=GS F6PIS1_MONDO/1-216        AC F6PIS1.1
#=GS I3LLL0_PIG/77-296         AC I3LLL0.2
#=GS A0A2Y9I264_NEOSC/1-223    AC A0A2Y9I264.1
#=GS A0A3P4LZF6_GULGU/1-104    AC A0A3P4LZF6.1
#=GS A0A6I8N665_ORNAN/36-288   AC A0A6I8N665.1
#=GS A0A3Q7SU40_VULVU/1-223    AC A0A3Q7SU40.1
#=GS I3NCH4_ICTTR/1-224        AC I3NCH4.1
#=GS F6YLD8_HORSE/1-223        AC F6YLD8.1
#=GS F7GXS1_MACMU/1-223        AC F7GXS1.2
#=GS A0A2R8ZG09_PANPA/1-223    AC A0A2R8ZG09.1
#=GS M3Z8H5_MUSPF/1-229        AC M3Z8H5.1
#=GS K7EI61_ORNAN/17-269       AC K7EI61.1
#=GS A0A452E8F0_CAPHI/6-226    AC A0A452E8F0.1
G3I4J4_CRIGR/1-201                   ................--------------..-------MWAAFPCGPCIPIMLGLASLTAFFIITTAVLAERLFRR-PHPD.............S.SKHAPTLVWRPGGELWIEPTSSARERSE.DWYGSSIPLLMDRAPDPPTPGG............TLEGRATAPPAPSIPH..............SSPSSLVPQTPPEVPA....QSTFWRPQAQEERLHATGLVSWVEPDMSQEA..GMQ..VGSPKSWRMRQGSLE..PDWGLQPRVTLEQISAFWKREGRTSVG............................
H2QAV2_PANTR/1-223                   ................MPLTPEPPSGCVEG..PPAWEAAPWPSLPCGPCIPIMLVLATLAALFILTTAVLAERLFRRALRPD.............P.SHRAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLTDRAPEPPTQVG............TLEARATAPPAPSAPN..............SAPSNLGPQTVLEVPP....RSTFWGPQPWEGRPPTTGLVSWAEPEQRPEA..SVQ..FGSPQARRQRPGSPD..PEWGLQPRVTLEQISAFWKREGRTSVG............................
A0A4W2DMJ4_BOBOX/1-217               .......mpptpqpps--------------..-VQTEASSWAPLPCGPCIPIMVALATLAAVFLLATAVLAERLFRRSLQLD.............P.SIRAPTLVWRPGGELWIEPIGTPRERSE.DWYGSEVPLLTDRAPDPPAQGG............TLEARATAPPAPSPPH..............SPPSSLVPQTPPNART....RSTFWGPQVWEERPQAPGLVSWAEPEQRPEA..NAY..PGSPQARRVRPGSPD..LEWGLQPRVTLEQISAFWRREGRSSVG............................
A5PKB9_BOVIN/1-217                   .......mpptpqpps--------------..-VQTEASSWAPLPCGPCIPIMVALATLAAVFLLATAVLAERLFRRSLQLD.............P.SIRAPTLVWRPGGELWIEPIGTPRERSE.DWYGSEVPLLTDRAPDPPAQGG............TLEARATAPPAPSPPH..............SPPSSLVPQTPPNART....RSTFWGPQVWEERPQAPGLVSWAEPEQRPEA..NAY..PGSPQARRVRPGSPD..LEWGLQPRVTLEQISAFWRREGRSSVG............................
L5MJD6_MYODS/1-93                    ................--------------..--------------------MLGLAMLAALFLLTTAVLAERLFRRSLRPG.............P.SPHAPTLVWRPGGELWIEPTGTPRERSE.DWETET----------------............----------------..............----------------....-------------------------------..---..---------------..---------------------------ltpaqsanegsqageaalpsagaqsrin
A0A5J5MPB7_MUNRE/1-217               .......mpptpapps--------------..-GQTEASSWVPLPCGPCIPIMVALAALAAVFLLATAVLAERLFRRSLPPD.............P.SIRAPTLVWRPGGELWIEPRGTPRERSE.DWYGSEVPLLTGGAPDPPAQGG............TLEARATAPPAPSTPR..............SPASSLVPQTPPNAPT....QSTFWGPQVWEERPQAPGLVSWAEPEQRPED..SAY..PGSPQARRVRPGSPD..LEWGLQPRVTLEQISAFWRREGRSSVG............................
L8IXN7_9CETA/102-192                 ..............pd--------------..--------------------------------------------------.............-.----------------------------.----------------------............----------------..............---PSLVPQTPPNART....RSTFWGPQVWEERPQAPGLVSWAEPEQRPEA..NAY..PGSPQARRVRPGSPD..LEWGLQPRVTLEQISAFWRREGRSSVG............................
H0XZE3_OTOGA/1-225                   ................MPVTPEQPAGQAEG..PPASDAAAWPPLPCGPCIPIMVGLASLAALFILTTAVLAERLFRRALRPD.............P.GRCAPTLVWRPGGELWIEPVGTPRERSE.DWYGSAVPLLTDRAPEPPTPGG............TLEARATAPPAPSIPH..............SAPSSLGPQTPPLVPV....RSTFWGPHPWEARPPATGLVSWAEPEQSPEAetRTQ..FGSPQFQRLRAGSPE..PDWSLQPRVTLEQISAFWRREGRTSVG............................
G3QX39_GORGO/1-223                   ................MPLTPEPPSGRVEG..PPAWEAAPWPSLPCGPCIPIMLVLATLAALFILTTAVLAEHLFRRALRPD.............P.SHRAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLTDRAPEPPTQVG............TLEARATAPPAPSAPN..............SAPSNLGPQTVLEVPA....RSTFWGPQPWEGRPPATGLVSWAEPEQRPEA..SVQ..FGSPQARRQRPGSPD..PEWGLQPRVTLEQISAFWKREGRTSVG............................
A0A673TZU1_SURSU/1-223               ................MSSTPEQPSGHMEG..LSESELVTWPPLPCGPCIPIMLALAFLAALFLLTTAVLAERLFRRSLRPD.............P.NYHAPTLVWRPGGELWIEPRGTPRERSE.DWYGSAVPLLMDGAPDPPTPGG............TLEARATAPPVPTAPL..............TPPSSVVLQSPPRAPV....RSTFWGPQALEERPYAPGLVSWAEPELRPEA..SMH..LGSPQPRRQRLGSPD..PEWGLQPRVTLEQISAFWRREGRTSVG............................
CP054_RAT/1-224                      ................MPATPQQPSGHTEGltEPTSEAAMWVVIPCGPCIPIMLGLASLTAFFIITTAVLAERLFRR-PQPD.............P.SQRAPTLVWRPGGELWIEPTSSARERSE.DWYGSSIPLLMDRAPDPPTPGG............TLEGRATAPPAIPTPH..............PSPSSLVPQTPPEVPA....QSTFWRPQTQEESPYATGLVSWVGPEPMAEA..GLE..VGSPRAWRLRQGSLE..PDWSLQPRVTLEQISAFWKREGRTSVG............................
A0A1U7UAT5_CARSF/1-221               ................MPSTPQQSSGHMEG..TPTSEAASLPPLPCGPCLPIMLGLASLAALFILTTAVLAERLFRRSLRPD.............P.SHRAPALVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLMDRAPGPPTPGG............TLEARATAPPAPSTLH..............SAPSSLGPQTPPEFPA....RSTFWGPQ--EGMPPAVGQVSWAEPEQRPET..SMQ..FGSPQVQRQRPGSPV..PEWGLQPRVTLEQISAFWRRESRTSVG............................
A0A2Y9EST6_PHYMC/1-223               ................MPPTPEQPSGHMEG..PPASETSSWPPLPCGPCVPIMLALAALAAVFLLTTAVLAERLFRRSLRPD.............P.SICAPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLMDQAPDPPTQGG............ALEARVTAPPAASAPY..............SPPSSLVPQTPPNAPT....RSTFWRPQVWEERPHTPGLVSWAESEQRPEA..SAY..PGSPQARRLRPGSPD..PEWGLQPRVTLEQISAFWRREARTSVG............................
A0A484GT94_SOUCH/1-223               ................MPPTPEQPSGHMEG..PPASEASSWPPLPCGPCVPIMLALAALAAVFLLTTAVLAERLFRRSLRPD.............P.SICAPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLMDRAPDPPTQGG............ALEARVTAPPAPSAPY..............SPPSSLVPQTPPNAPT....RSTFWRPQVWEERPHTPGLVSWAEPEQRPEA..SAY..PGSPQARRLRPGSPD..PEWGLQPRVTLEQISAFWRREARTSV-s...........................
W5P637_SHEEP/4-117                   .....plpspsprdsl--------------..--------------------------------------------------.............-.----------------------------.----------------------............--APRGPAP-------..............SPPIGVARPAPPVSPSgariPSTFWGPQVWDERPQAPGLVSWAEPEQRPEA..SAY..PGSPQARRVRPGSPD..LEWGLQPRVTLEQISAFWRREGRSSVG............................
CP054_HUMAN/1-223                    ................MPLTPEPPSGRVEG..PPAWEAAPWPSLPCGPCIPIMLVLATLAALFILTTAVLAERLFRRALRPD.............P.SHRAPTLVWRPGGELWIEPMGTARERSE.DWYGSAVPLLTDRAPEPPTQVG............TLEARATAPPAPSAPN..............SAPSNLGPQTVLEVPA....RSTFWGPQPWEGRPPATGLVSWAEPEQRPEA..SVQ..FGSPQARRQRPGSPD..PEWGLQPRVTLEQISAFWKREGRTSVG............................
A0A2R8MFT0_CALJA/1-223               ..............ml--LTPEPPSGHVEG..TPTWEAAPWPLLPCGPCIPIMLALAALAALFILTTAVLAERLFRRTLHPD.............P.SHHAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLTDRAPEPPTQMG............ALEARATDPPAPSALH..............SAPSSLGPQTPPEVPA....RSTFWGPQPWERRPPTTGLVSWAEPEQRPEA..SAQ..SGSPQARRQRPGSPD..PEWGLQPRVTLEQISAFWKREGRTSVG............................
H2NRX5_PONAB/1-223                   ................MPLTPEPPSGRMEG..PPAWEAAPWPSLPCGPCIPIMLVLATLAALFILTTAVLAECLFRRTLRPD.............P.SHRAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLTDRAPEPPTQVG............TLEARATAPPASLAPN..............SAPSNLGPQTLLEVPA....RSTFWGPQPWEGRPLATGLVSWAEPEQRPEA..SVQ..FGSPQARRQRPGSPD..PEWGLQPRVTLEQISAFWKREVRTSVG............................
A0A384BLZ5_URSMA/98-148              ...............s--------------..--------------------------------------------------.............-.----------------------------.----------------------............----------------..............----------------....--------------------------ARPEA..SVP..LGSPQAQRQRLGSPD..PEWGLQPRVTLEQISAFWRREGRTSVG............................
A0A2F0B698_ESCRO/31-253              ................MPPTPEQPSGHMEG..PPASEASSWPPLPCGPCVPIMLALAALAAVLLLTTAVLAERLFRRSLRPD.............P.SICAPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLMDQAPDPPTQGG............ALEARVTAPPAPSAPY..............SPPSSLVPQAPPNAPT....HSTFWRPPVWEERPHTPGLVSWAEPEQRPEA..SAY..PGSPQARRLRPGSPD..PEWGLQPRVTLEQISAFWRREARTSVG............................
A0A4X2KS28_VOMUR/38-253              ................MSAALDQPPGQVED..PVMPQPSQWPPLLCGPCIPIMLALALVAAVFLLATAVLAERLFRRSLRSD.............P.GVQGPSLVWRPGGELWIEPSGTAHERSE.DWYGATAPLLHSHVTEPHFLGG............TLEVQATAPPIPD---..............SPLCPSAPPQAPESPA....-STFCIANTWEERPQTTGLVAWFEPQPVPEP..---..LPPPFYGIRRPRSPE..PDWGLQPRVTLEQISAFWRRENRVHGG............................
A0A2U3Y2X2_LEPWE/1-223               ................MPSTPEQPSGHTEG..LPTSELGSWPPLPCGPCIPIMLALASLSALFLLTTAVLAERLFRRSQHPD.............P.STHAPTLVWRPGGELWIEPRGTPRERSE.DWYGSAVPLLMDQAPDPPIPGG............TLEAHATAPPAPLAPL..............SPSGSLVPRTPPRAPA....RSTFWGPQALNERPCVPGLVSWAESEQRPEA..NVY..LGSPQAQRQRLGSPD..PEWGLQPRVTLEQISAFWKREGRTSVG............................
A0A1S3AJX4_ERIEU/1-217               ................MPSTAALPPGPLEG..ATAEEPEPWPPLPCGPCVPIMLALGCLAALFLVATAVLAERLFRSSLRSP.............P.GSRPPTLVWRPGGELWIEPSGSPRERSE.DWYSSAVPLLTEGSPAPPTPGG............TLEARATAPPALPAPK..............PPP------VPPKPAV....QSTFWGAQAWEERPPAPGLVSWAEPEQRLEV..GGY..VGSPPPQRLRPGSPD..VEWGLQPRVTQEQISAFWKREGRTRVG............................
A0A1A6GCH5_NEOLE/1-131               ................--------------..--------------------MLGLASLAAFFIITTAVLAERLFRR-PHPG.............P.SQHAPTLVWRPGGELWIEPTSSARERSE.DWYGSSVPLLMDRAPDPPTPGG............TLEGRATAPPVPS---..............-IPLSLVPQTPPEVPA....QSTFWRPQTQEERLHATGL------------..---..---------------..---------------------------alip........................
A0A341BBP8_NEOAA/1-223               ................MPPTPEQPSGHMEG..PPASEASSWPPLPCGPCVPIMLALAALAAVFLLTTAVLAERLFRRSLRPD.............P.SICAPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLMDRAPDPPTQGG............ALEARVTAPPAPSAPY..............SPPSSLVPQTPPNAPT....RSTFWRPQVWEERPHTPGLVSWAEPEQRPEA..SAY..PGSPQAPRLRPGSPN..PEWGLQPRVTLEQISAFWRREARTSV-s...........................
A0A384AGV1_BALAS/1-223               ................MPPTPEQPSGHMEG..PPASEASSWPPLPCGPCVPIMLALAALAAVLLLTTAVLAERLFRRSLRPD.............P.SICSPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLMDQAPDPPTQGG............ALEARVTAPPAPSAPY..............SPPSSLVPQTPPNAPT....YSTFWRPQVWEERPHTPGLVSWAEPEQRPEA..SAY..PGSPQARRLRPGSPD..PEWGLQPRVTLEQISAFWRREARTSVG............................
A0A286XQI6_CAVPO/18-240              ................MPSTSTRLTGHMEG..PPATEATFWPPLPCGPCIPILLALASLAAFFILTTAVLAERLFRRSLHPD.............P.SHRVPTLVWRPGGELWIEPAGTARERSE.DWYGCEEPLLTDRSPDFPPPGG............TLEARASAPPAPSALH..............SSPSSSVPQEHPNILA....QSTFWGPQPCGERPPTTGLVSWVGPELRPEA..TPM..LGSATAWRPRPGSPE..PDWSLQPRVTLEQIAAFWRREGRTSV-s...........................
A0A340X1A2_LIPVE/1-223               ................MPPTPEQPSGHMEG..PPASEASSWPPLPCGPCVPIMLALATLAAVFLLTTAVLAERLFRRSLRPD.............P.SICTPSLVWRPGGELWIEPTGTPRERSE.DWYGSAAPLLRDRAPDPPTQGG............ALEARVTAPPAPSAPY..............SPPSSLVPQTPPNAPT....PSTFWRPQVWEEGPHTPGLVSWAEPEQRPEA..SAY..PGSPQARRLRPGSPD..PEWGLQPRVTLEQISAFWRREAPTSV-s...........................
CP054_MOUSE/1-224                    ................MPVTPQQPSGHTEGlpEPTAEAAVWVVIPCGPCIPIMLGLASLTAFFIITTAVLAERLFRR-PQPD.............P.SQRAPTLVWRPGGELWIEPTSSARERSE.DWYGSSMPLLMDRAPGPPTPGG............TLEGRATAPPATSAPY..............SSLSSLVPQTPPEVPA....QSTFWRPQTQEERPHDTSLVSWVGSEPMPEA..GLQ..VGSPRPWRPRQGSLE..PDWGLQPRVTLEQISAFWKREGRTSVG............................
A0A5E4C763_MARMO/1-224               ................MPATRGQPSEHMEA..PSASETALWPPLPCGPCIPIMLALASLAAFFILTTAVLAERLFRRSLRAD.............PgTHHAPTLVWRPGGELWIEPTGTARERSE.DWYGAAVPLLSCRAPDPPTPGG............TLEAQASAPLAPLAPH..............SAPSSLVLQTPPEVPA....QSTFWGPQSQEERPHATGLVSWAEPELRSEV..SMQ..LGSPKAWRQRPGSPE..PDWGLQPRVTLEQISAFWRREGRTSVG............................
A0A5G2QHF6_PIG/1-202                 ................MPPTPEQPSGPMEE..PLALAASSWPPLPCGPCVPIMLVLAALAAVFLLTTAVLAERLFRRSLRPD.............P.GTLAPTLVWRPGGELWIEPTGTPRERSE.DWYGSSVPLLMDRAPDPPTLGG............TLEARATAPPAPN---..............SPRNSLVPQTPPQAPA....RSTFWRPQVWEERPGGSGQEALI-----PSG..ASS..LGSPWRRSQLSGGVKagPAWVFDP--------------------qgled.......................
A0A3Q7WEU0_URSAR/1-223               ................MPSTPQQPSGHTVG..LPAAELGSWPPLACGPCIPIMLALASLAALFLLTTAVLAERLFRRSQHPD.............P.SNHAPTLVWRPGGELWIEPRGTPRERSE.DWYGSAVPLLMDRAPDPPTPGG............TLEARATAPPAPLAPL..............SPPSSLVPRPPPRVPA....RSTFRGPQALDERPCVPGLVSWAEPEQRPEA..SVP..LGSPQAQRQRLGSPD..PEWGLQPRVTLEQISAFWRREGRTSVG............................
J9P8N4_CANLF/150-281                 ........lrglvwlc--------------..--------------------------------------------------.............-.----------------------------.------SPLAHGPAPRPSHPWG............HIGGQSHSPTCPFSPT..............HPSWLLGPHTPHRAPA....CNTFWGPQASEERPYAPGLVSWAEPEQRPEA..NMH..LGSPQAQRQRLGSPD..FEWGLQPRVTLEQISAFWRREGRTSVG............................
V8PF27_OPHHA/379-491                 avmlgpptnvemlpps--------------..------SASPLSDCGNCLLIMVSLATVAAVFIVVSAVLCERVFRGSLPQE.............-.TGAVPT-VWRQGGTLWIEPPHNNRQPDVlSRPSATVPLWIQRS--------............----------------..............----------------....-------------------------------..---..---------------..---------------------------ndwfldvspag.................
A0A5N4CVY4_CAMDR/317-533             ................MPPTPEQPSGHMQG..PPASESAFWPLLPCGPCIPIMLALAALAAIFLLTTAVLAERLFRRSLRPD.............P.STYAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLMDRDPDPPTPGG............TLEARATAPPALSTPN..............SPSSSSVPQIPPKVPA....HSTFW-------RPPASGLVSWIEPEQRPEA..SVH..LGSPQAQRQRPGSPD..PEWGLQPRLS-----------------ggvkagpawvsesqgpgg..........
A0A671FDJ2_RHIFE/1-223               ...............v-PSTPEQPSGYMEG..PSASEPGSWSPLPCGPCIPIMLALACLAALFLLTTFVLAERLFRRSLHPD.............P.SSRAPTLVWRPGGELWIEPTGTPRERSE.DWYGSVVPLMMDQAPNPPTPGG............TLEARATAPPAPSIPH..............FPPKSLAPQPPPKPQV....SSTFWGPQVWQERSHAPGLVSWAEPEQRPDA..SVY..LGSPQAQRQRPGSPD..PEWGLQPRVTLEQISAFWRRESRTSVG............................
G1QCE9_MYOLU/1-226                   ................MPWTPEQPPGHMEG..PPASESASWPPLPCGPCIPIMLALALLAALFLLTTAVLAERLFRRSLRPG.............P.SHHPPTLVWRPGGELWIEPTGTPRERSE.DWYGSEVPLLMDQAPDPPVPGG............TLEARATAPPAPPAPSt...........prSPPSFFVPQIPPQAPA....PSTFWGPQAWEGRPHAPGLVSWAEPEQRPEP..SMN..LGSPQARRQRPGSPD..PEWGLQPRVTLEDISAFWRRESRTSVG............................
L9KUH4_TUPCH/1-216                   ................MPSTPEQPSGPL--..-----DASWPQLPCGPCIPIMLALASLAALFILTTAVLAERLFRRSLRPD.............P.SLRAPTLVWRPGGELWIEPTGTARERSE.DWYGSAVPLLMDRAPDPPTPGG............TLEARATAPPAPPAPH..............SPPSSLVPQTPPEVPP....RSTFWKPQPWVEERPAAGLVSWGEPEQRPEA..HMQ..FGSPQARRQRPGSPE..PDWGLQPRVTLEQISAFWRREGRTSVG............................
L8IXN7_9CETA/1-106                   .......mpptpqpps--------------..-VQTEASSWAPLPCGPCIPIMLALATLAAVFLLATAVLAERLFRRSLQPD.............P.SIRAPTLVWRPGGELWIEPIGTPRERSE.DWYGSEVPLLTDCAPDPS----............----------------..............----------------....-------------------------------..---..---------------..---------------------------l...........................
A0A1S3ER18_DIPOR/1-218               ................MPLTPEQPLGYTED..LPMSEAALWPPLPCGPCIPIMLALASLAAFFIVTTAVLAERLFRRSLRPD.............P.HQRAPTLVWRPGGELWIEPTSTARERSE.DWYGSAVPLLMDRGLEPPAPGA............SMEARATAHPPPSAPH..............PAPGNLGGPV-----C....RGTFGEPQLWEETPTTTGLVSWIGPELRPEA..SGT..HEPPQAWRQRPGSPE..PDWSLQPRVTLEQISQFWKREGRTSVG............................
T0NR12_CAMFR/107-322                 ................MPPTPEQPSGHMQG..PPASESAFWPLLPCGPCIPIMLALAALAAIFLLTTAVLAERLFRRSLRPD.............P.STYAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLMDRDPDPPTPGG............TLEARATAPPALSTPN..............SPSSSSVPQIPPKVPA....HSTFW-------RPPASGLVSWIEPEQRPEA..SVH..LGSPQAQRQRPGSPD..PEWGLQPRVTLEQISAFWRREGRTSVG............................
A0A0D9SBY8_CHLSB/1-223               ................MPSTPEPPSGRVEG..PPTWEAAPWPSLPCGPCIPIMLALATLAALFILTTAVLSERLFRRALHPD.............P.SHHAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLTDRAPEPPTPVG............VLEARATAPHAPSAPN..............SAPSSLGPQTPPEVPA....RSTFWGPQPWEGRPPGMGLVSWAEPEQRPEA..TAQ..FGSPQVRRQRPWSPD..PEWGLQPRVTLEQISAFWKREGRTSVG............................
A0A2U4A9F6_TURTR/1-223               ................MPPTPEQPSGHMEG..PPASEASSWPPLPCGPCVPIMLALAALAAVFLLTTAVLAERLFRRSLRPD.............P.SICAPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLMDRAPDPPTQGG............ALEARVTAPPAPSAPY..............SPPSSLVPQTPPNAPT....RSTFWRPQVWEERPHTPGLVSWAEPEQRPEA..SAY..PGSPQARRLRPGSPD..PEWGLQPRVTLEQISAFWRREARTSV-s...........................
A0A2Y9L806_ENHLU/1-229               ................MPSTPEQPFGHTGG..LPAPEMGSWPPLPCGPCIPIMLALASLAALFLLTTAVLAERLFRRSQHAD.............P.SNHAPTLVWRPGGELWIEPRGTPRERSE.DWYGSAVPLLMDRAPDPPTPGG............TLEARATAPPAPFAPPtpl........aplSPPSSLGPHTPPRAPA....RSTFWGPQALDERPCAPGLVSWAEPEHRPEA..IVH..LGSPQAQRQQLGSPD..PEWGPQPRVTLEQISAFWRRESRTSVG............................
A0A2Y9PAN9_DELLE/1-223               ................MPPTPEQPSGHMEG..PPASEASSWPPLPCGPCVPIMLALAALAAVFLLTTAVLAERLFRRSLRPD.............P.SICAPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLMDRAPDPPTQGG............ALEARVTAPPAPSAPC..............SPPSSLVPQTPPNAPT....RSTFWRPQVWEERPHTPGLVSWAEPEQRPEA..SAY..PGSPQARRLRPGSPD..PEWGLQPRVTLEQISAFWRREARTSV-s...........................
L5KJM5_PTEAL/1-223                   ................MPLTPEQPSGYMEG..PPASEPASWPPLPCGPCVPIMLALASLAALFLLSTAVLAERLFRRSLRPD.............P.SHRAPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLMDQAPDPHNPRG............TLEARATAPPAPVIPH..............SPPSSLVSQPPPKAPA....RSTFWGPQAWEERLHAPGLVSWAEPEQRPEA..SVC..LGSPQTRRQRPGSPD..SEWGLQPLVTLEQISAFWRREGRTSM-d...........................
M3WH47_FELCA/1-211                   ................MPSTPEQPSGHVEG..LPESELVTWPPLPCGPCIPIMLALACLAALFLVTTAVLAERLFRRSLHPD.............P.SNRAPTLVWRPGGELWIEPRGTPRERSE.DWYGSAVPLLMDGAPDPPISGG............TLEARATAPPAPIAPL..............SPPSSLGLQSPPRAPV....RSTFWGPQALEERPYAPGLVSWAEPEQRPEA..SMH..LGSPQTRRQRLGSSD..LEWGPG---------------------tslgsests...................
G3W526_SARHA/1-213                   ................MSAALEQPP---ED..PGLPQSSPWPPLLCGPCIPIMLGLALVAAIFLLATAVLAERLYRRSLESD.............P.RVQGPSLVWRPGGELWIEPVGTPHERSE.DWYGSTAPLLHSQAPEPPILGG............TLEMRATAPPLPD---..............SSLCPLVSPQAPESPG....-STFCTANPWEERPRTTGLVGWFEPQPGPEP..---..SPPPLYSIRRPGSPE..PDWSLQPRVTLEQISAFWRRESRVHGG............................
A0A643C520_BALPH/1-34                ................MPPTPEQPSGHMEG..PPASEASSWPPLPCGPS---------------------------------.............-.----------------------------.----------------------............----------------..............----------------....-------------------------------..---..---------------..---------------------------sah.........................
A0A402FPY3_9SAUR/2-78                ......pppatvptvs--------------..------------DCGTCLLIMASLAFVAGLFMVISGILCTCLFRGSLP--.............P.EARGVPSVWRQGGSLWIEPTRNRRE---.----------------------............----------------..............----------------....-------------------------------..---..---------------..---------------------------sdvls.......................
A0A4U1FLC5_MONMO/1-223               ................MPPTPEQPSGHMEG..PPASEASSWPPLPCGPCVPIMLALAALAAVFLLTTAVLAERLFRRSLRPD.............P.SICAPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLMDRAPDPPTQGG............ALEARVTAPPAPSAPY..............SPPSSLVPQTPPNAPT....RSTFWRPQVWEERPHTPGLVSWAEPEQRPEA..SAY..PGSPQARRLRPGSPD..PEWGLQPRVTLEQISAFWRREARTSV-s...........................
A0A6G1B353_CROCR/1-223               ................MPSTPEQPSGHMEG..LPEPELVTWPPPPCGLCIPIMLGLASLAALFLLTTAVLAERLFRRSLQPD.............P.SYRAPTLVWRPGGELWIEPRGTPRERSE.DWYGSAVPLLMDGAPDPPTPGG............TLEARATAPPAPTAPL..............SPPSSLALQSPPRAPV....RSTFWGPQALEERPYTRGLVSWAEPELRPEA..SMH..LGSPQPRRQRLGSPD..PEWGLQPRVTLEEISAFWRREGRASVG............................
A0A384BLZ5_URSMA/1-101               ................MPSTPQQPSGHTVG..LPAAELGSWPPLACGPCIPIMLALASLAALFLLTTAVLAERLFRRSQHPD.............P.SNHAPTLVWRPGGELWIEPRGTPRERSE.DWYGSARP--------------............----------------..............----------------....-------------------------------..---..---------------..---------------------------............................
A0A2U3VQB7_ODORO/1-223               ................MPSTPEQPSGHTEG..LPTSELGSWPPLPCGPCIPIMLALASLAALFLLTTAVLAERLFRRSQHPD.............P.STHAPTLVWRPGGELWIEPKGTPRERSE.DWYGSAVPLLMDRAPDPPTPGG............TLEARATAPPAPLAPL..............SPSGSLVPHTPPRAPA....RSTFWGPQPWDKRPCVPGLVSWAEPEQRPEA..NVY..LGSPQAQRQRLGSPD..REWGLQPRVTLEQISAFWRREGRASVG............................
A0A2K5XKG2_MANLE/31-216              ...........xxxxx--------------..----------------------------XLFILTTAVLAERLFRRALRPD.............P.SHHAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLTDQAPEPPTPVG............VLEARATAPHAPSAPN..............SAPSSLGPQTPPEVPA....RSTFWGPQPWEGRPPGTGLVSWAEPEQRPEA..TAQ..FGSPQARRQRPRSPD..PEWGLQPRVTLEQISAFWRREGRTSVG............................
L5MIA8_MYODS/1-202                   ................-----------MEG..PPAAESASWPPLPCGPCIPIMLGLAMLAALFLLTTAVLAERLFRRSLRPG.............P.SPHAPTLVWRPGGELWIEPTGTPRERSE.DWEGS----------HPPVPGG............TLEARATAPPAPSTPH..............APPSFFVPQIPPQSPA....PSTFWGPHAWEGRPHAPGLVSWAEPEQRPEP..SMS..LGSPQARRQRPGSPD..PEWGLQPRVTLEDISAFWRRESRTSVG............................
A0A2K6DDL4_MACNE/1-223               ................MPSTPEPPSGRMEG..PPTWEAAPWPSLPCGPCIPIMLALATLAALFILTTAVLAERLFRRALRPD.............P.SHHAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLTDRAPEPPTPVG............VLEAQATAPYAPSAPN..............SAPSSLGPQTPPEVPA....RSTFWGPQPWEGRPPGTGLVSWAEPEQRPEA..RAQ..FGSPQARRQRPRSPD..PEWGLQPRVTLEQISAFWRREGRTSVG............................
A0A1U7QBZ5_MESAU/1-221               ................MPSTPGQPLGHTEG..LPESTAAE-AVLPCGPCIPIMLGLASLTAFFIITTAVLAERLFRR-PNPD.............T.RQRAPTLVWRPGGELWIEPTSSARERSE.DWYGSSMPLLMDRVPDPPTPGG............TLEGRATAPPAPSIPH..............SSPSSLVPQTPPEVSA....QSTFWRPQAQEERLDATGLASWIEPEMRQEA..GMQ..VGSPKSWRMRQGSLE..PDWGLQPRVTLEQISAFWKREGRTSVG............................
G3TX68_LOXAF/1-223                   ................MPSTPGQPTGHMEG..PPASESASWSPLPCGPCVPIMLALACLAALFLLTTAVLAERLFRRSPRLD.............P.SNRTPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLMDGAPEALNPGG............TLEARATAPSAPSAPH..............SPPSSLVFQAPPQVPA....RSTFCVPQPWEERSHNTGMVSWAEPEPRPGD..SVY..LGSPRAQRHRPGSPE..PGWGLQPLVTLEQISAFWRREGRTSVG............................
A0A2Y9E5D7_TRIMA/1-223               ................MPSTPEQPSGHMEE..TSASESASWAPLPCGPCVPIMLTLASLAALFLLTTAVLAERLFRRSLRQD.............P.SNHTPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLTDPAPETPNPGG............TLEARATAPSAPSAPY..............APPSALVSQAAPQAPV....RSTFWVPQPWEERPHNPGMVSWAEPELRPGA..SVF..LGNPQSRRQRPGSPE..PDWGLQPRVTLEQISAFWRREGRTSVG............................
F6PIS1_MONDO/1-216                   ................MSAPLEQLPGQVEN..PVMHQPSQWPPILCGPCIPIMLALALLAAIFLLATAVLAERLFRRSLRSD.............P.SVGRPSLVWRPGGELWIEPVGTPHERSE.DWYGAIAPLLHSQVTEATIPRG............TLEAQATAPPNPD---..............SPPCPSVLPWAPESPG....-STFWMANPWEERPRTTGLVGWCEPQPGPEP..---..LSSPFYGSHRPGSPE..PDWGLQPRVTLEQISAFWRRENRVGGG............................
I3LLL0_PIG/77-296                    ................MPPTPEQPSGPMEE..PLALAASSWPPLPCGPCVPIMLVLAALAAVFLLTTAVLAERLFRRSLRPD.............P.GTLAPTLVWRPGGELWIEPTGTPRERSE.DWYGSSVPLLMDRAPDPPTLGG............TLEARATAPPAPN---..............SPRNSLVPQTPPQAPA....RSTFWRPQVWEERPHAPGLVSWAEPEQRPEA..SGY..LGSPQARRQRPGSPD..PEWGLQPRVTLEEISAFWRREGRTSVG............................
A0A2Y9I264_NEOSC/1-223               ................MPSTPEQPSGHTEG..LPTSELGSWPPLPCGPCIPIMLALASLSALFLLTTAVLAERLFRRSQHPD.............P.STHAPTLVWRPGGELWIEPRGTPRERSE.DWYGSAVPLLMDQAPDPPIPGG............TLEAHATAPPAPLAPL..............SPSGSLVPRTPPRAPA....RSTFWGPQALDERPCVPGLVSWAESEQRPEA..NVY..LGSPQAQRQRLGSPD..PEWGLQPRVTLEQISAFWKREGRTSVG............................
A0A3P4LZF6_GULGU/1-104               ................MPSTPEQPFGHTEG..LPAPEMGAWPPLPCGPCIPIMLALASLAALFLLTTAVLAERLFRRSQRAD.............P.SNHAPTLVWRPGGELWIEPRGTPRERSE.DWYGSAVPLLM-----------............----------------..............----------------....-------------------------------..---..---------------..---------------------------............................
A0A6I8N665_ORNAN/36-288              ....spdpesptplpp--------------..--------LAPLPCGPCIPIMLALGSVAAFFLLSTAVLAERLFRRSLVREasassaasassaaPgSTRSAGWVWGPGGELWIEPSRTAHQRSE.DWYGAAVPLLRSQDPGLSVPGSpltqasappapwTIEARASTPPPPASPFssralsvelgprpgGSPSPPPPARPPRPPA....-STFWMPPPWEERPQEGSLVSWEEPGAPGSG..GGWggQPGPFWESPGPGSLE..PEWGLQPRVTLEQISAFWRREGRG---vg..........................
A0A3Q7SU40_VULVU/1-223               ................MSSTPEQPSGQQEG..LPVSELVPWPPLPCGPCIPIMLALASLAALFLLTTAVLAERLFRRSLHSD.............P.GNHAPTLVWRPGGELWIEPRGTARERSE.DWYGSAVPLLMDQPPDPPTPGG............TLEARATAPPVPLAPL..............TPPGSLAHHTPQRAPA....CNTFWGPQASEERPYAPGLVSWAEPEQRPEA..NMH..LGSPQAQRQRLGSPD..FEWGLQPRVTLEQISAFWRREGRTSVG............................
I3NCH4_ICTTR/1-224                   ................MPATRGQPSEHMEA..PSASETALWPPLPCGPCIPIMLALASLAAFFILTTAVLAERLFRRSLRAD.............PgTHHAPTLVWRPGGELWIEPTGTARERSE.DWYGAAVPLLSGRAPDPPTPGG............TLEAQASAPLAPLAPH..............SAPSSLVLQTPPEVPA....QSTFWGPQPQEERPHATGLVSWAEPELRSEV..SMQ..LGSPKAWRQRPGSPE..PDWGLQPRVTLEQISAFWRREGRTSVG............................
F6YLD8_HORSE/1-223                   ................MPSTPGQPSEHMEG..PPVLEAASWPPLPCGPCIPIMLALASLSALFLLTTAVLAERLFRRSPQPD.............P.RNQAPTLVWRPGGELWIEPTGTPRERSE.DWYGSAVPLLRDQAPDPPTPGG............TLEARATAPPASSAPH..............SPPRSLVPQTPPKVLA....HSTFWGPQVGEERPHAPGLVSWAEPEQGPVA..SVY..LGSPQSRRQRPGSPD..PEWGLQPRVTLEQISAFWRREGRTSVG............................
F7GXS1_MACMU/1-223                   ................MPSTPEPPSGRMEG..PPTWEAAPWPSLPCGPCIPIMLALATLAALFILTTAVLAERLFRRALRPD.............P.SHHAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLTDRAPEPPTPVG............VLEAQATAPYAPSAPN..............SAPSSLGPQTPPEVPA....RSTFWGPQPWEGRPPGTGLVSWAEPEQRPEA..RAQ..FGSPQARRQRPRSPD..PEWGLQPRVTLEQISAFWRREGRTSVG............................
A0A2R8ZG09_PANPA/1-223               ................MPLTPEPPSGRVEG..PPAWEAAPWPSLPCGPCIPIMLVLATLAALFILTTAVLAERLFRRALRPD.............P.SHRAPTLVWRPGGELWIEPMGTPRERSE.DWYGSAVPLLTDRAPEPPTQVG............TLEARATAPPAPSAPN..............SAPSNLGPQTVLEVPP....RSTFWGPQPWEGRPPTTGLVSWAEPEQRPEA..SVQ..FGSPQARRQRPGSPD..PEWGLQPRVTLEQISAFWKREGRTSVG............................
M3Z8H5_MUSPF/1-229                   ................MPSTPEQPFGHTGG..LPVPEMGSWPPLPCGPCIPIMLALASLAALFLLSTAVLAERLFRRSQHAD.............P.SHHAPTLVWRPGGELWIEPRGTPRERSE.DWYGSAVPLLMDRAPDPPTPGG............TLEARATAPPAPSAPPtpl........aplTPPSSLGPHTPPRAPV....RSTFWGPQALNERPCAPGLVSWAEPEHRPEA..TVH..LGSPQAQRQQLGSPD..LEWGPQPRVTLEQISAFWRRESRTSVG............................
K7EI61_ORNAN/17-269                  ....spdpesptplpp--------------..--------LAPLPCGPCIPIMLALGSVAAFFLLSTAVLAERLFRRSLVREasassaasassaaPgSTRSAGWVWGPGGELWIEPSRTAHQRSE.DWYGAAVPLLRSQDPGLSVPGSpltqasappapwTIEARASTPPPPASPFssralsvelgprpgGSPSPPPPARPPRPPA....-STFWMPPPWEERPQEGSLVSWEEPGAPGSG..GGWggQPGPFWESPGPGSLE..PEWGLQPRVTLEQISAFWRREGRG---vg..........................
A0A452E8F0_CAPHI/6-226               ............arqeMPPTPEPPSGQ---..---TEASSWAPLPCGPCIPIMVALATLAAVFLLATAVLAERLFRRSLRPD.............P.SIRAPTLVWRPGGELWIEPIGTPRERSE.DWYGSEVPLLTDNAPDLPAQGG............TLEARATAPPSPSAPR..............PPPSSLVSQTPANAPN....RSTFWGPQVWDERPQAPGLVSWAEPEQRPEA..SAY..PGSPQARRVRPGSPD..LEWGLQPRVTLEQISAFWRREGRSSVG............................
#=GC seq_cons                        ................MPsTP-QPoGphEG...PssEsusWPPLPCGPCIPIMLALAsLAAlFLLTTAVLAERLFRRSL+PD.............P.Sp+APTLVWRPGGELWIEPpGTPRERSE.DWYGSAVPLLhDpAP-PPs.GG............TLEARATAPPAPsuP...............SsPSSLsPQoPPpsPs....pSTFWtPQshEERP.ssGLVSWAEPEQRPEA..us...hGSPQApR.RPGSPD..PEWGLQPRVTLEQISAFWRREuRTSVG............................
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