GenomeNet

Database: Pfam
Entry: DUF4694
LinkDB: DUF4694
Original site: DUF4694 
#=GF ID   DUF4694
#=GF AC   PF15765.7
#=GF DE   Domain of unknown function (DUF4694)
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   Jackhmmer:Q7Z2V1
#=GF GA   27.00 27.00;
#=GF TC   45.80 45.80;
#=GF NC   20.30 19.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR031520;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is found in eukaryotes. Proteins in this
#=GF CC   family are typically between 154 and 217 amino acids in length.
#=GF CC   There is a conserved SSGY sequence motif.
#=GF SQ   39
#=GS L5JPY2_PTEAL/1-55         AC L5JPY2.1
#=GS J9P7M3_CANLF/1-157        AC J9P7M3.1
#=GS A0A212CYB1_CEREH/93-248   AC A0A212CYB1.1
#=GS A0A3Q7U1D3_VULVU/26-182   AC A0A3Q7U1D3.1
#=GS A0A2Y9HWY9_NEOSC/102-258  AC A0A2Y9HWY9.1
#=GS L5M9B6_MYODS/14-171       AC L5M9B6.1
#=GS A0A2Y9RXE0_TRIMA/18-174   AC A0A2Y9RXE0.1
#=GS A0A5N4CXI1_CAMDR/1-116    AC A0A5N4CXI1.1
#=GS A0A5F5XUX6_FELCA/89-230   AC A0A5F5XUX6.1
#=GS A0A5F9ZHF3_HUMAN/1-153    AC A0A5F9ZHF3.1
#=GS A0A2I3GGE4_NOMLE/48-200   AC A0A2I3GGE4.1
#=GS A0A1U7U177_CARSF/66-192   AC A0A1U7U177.1
#=GS A0A384BN70_URSMA/83-239   AC A0A384BN70.1
#=GS A0A1U7RKJ5_MESAU/26-179   AC A0A1U7RKJ5.1
#=GS A0A452CJX7_BALAS/63-219   AC A0A452CJX7.1
#=GS A0A3Q2I1T9_HORSE/51-202   AC A0A3Q2I1T9.1
#=GS A0A2R8ZDF8_PANPA/64-216   AC A0A2R8ZDF8.1
#=GS E1BNX5_BOVIN/1-156        AC E1BNX5.2
#=GS A0A2I2YW75_GORGO/64-216   AC A0A2I2YW75.1
#=GS A0A2U3Z969_LEPWE/102-255  AC A0A2U3Z969.1
#=GS W5QBI8_SHEEP/61-221       AC W5QBI8.1
#=GS A0A2Y9L7D5_ENHLU/11-167   AC A0A2Y9L7D5.1
#=GS H2NQG5_PONAB/64-216       AC H2NQG5.1
#=GS S9XWW7_CAMFR/10-128       AC S9XWW7.1
#=GS A0A1S3ET74_DIPOR/103-257  AC A0A1S3ET74.1
#=GS A0A2K5R2S5_CEBCA/45-197   AC A0A2K5R2S5.1
#=GS TNT_HUMAN/64-216          AC Q7Z2V1.1
#=GS A0A091DR12_FUKDA/1-127    AC A0A091DR12.1
#=GS A0A4W2DP33_BOBOX/65-220   AC A0A4W2DP33.1
#=GS A0A2U3ZCJ0_ODORO/57-213   AC A0A2U3ZCJ0.1
#=GS A0A5F8A729_MACMU/1-153    AC A0A5F8A729.1
#=GS A0A2I3RAY8_PANTR/64-216   AC A0A2I3RAY8.1
#=GS A0A1A6GXB1_NEOLE/75-228   AC A0A1A6GXB1.1
#=GS L8I8Q6_9CETA/1-156        AC L8I8Q6.1
#=GS G3U887_LOXAF/48-202       AC G3U887.1
#=GS A0A3Q7XAA5_URSAR/16-172   AC A0A3Q7XAA5.1
#=GS A0A0D9SBY7_CHLSB/63-215   AC A0A0D9SBY7.1
#=GS D3Z9W1_RAT/26-176         AC D3Z9W1.1
#=GS A0A2Y9FWY6_PHYMC/64-219   AC A0A2Y9FWY6.1
L5JPY2_PTEAL/1-55                    ..........mpp----------------------..----------------.....------------------------------...----.-----RSLDQS..SDTSHRSSGYAGDEENSEVSLV.GSSRI.VRLEG.KSE---------------------.---.-------------sslpgstahsr
J9P7M3_CANLF/1-157                   .............LDKPDQLPPTFLQGRNGESAAW..NAQGQAPSLLPPSVES.....QPPTWPHHDTGATQKPLRVSGGSLRNPWSS...ESGL.LSLQQSSLGKCsdSDISLLSSGYAGDEENSEVSLL.GSTPI.LRLQR.RLLTQAGSALTSQLCAVYSPSQIG.NRL.ASQAHSVKQTGGE...........
A0A212CYB1_CEREH/93-248              .............LEKPSQLPPTFLQGRQGESPSG..EAQEPGAGLQSPSLEP.....QSPAWPSHDAEATQEPLRDSSGHLGSTVSH...DSSVlSSLLHSSLERC..IDISRLSRGYAGDEENSEVSLP.GSHQM.VRLSR.RLHTQAGGAQTNQVCAVYSPKQLK.RRL.ARQANSTSQTGRE...........
A0A3Q7U1D3_VULVU/26-182              .............LDKPDQLPPTFLQGRNGESAAW..NAQGQAPSLSPPSVES.....QPPTWPHHDTGATQKPLRVSGGGLRNPWSS...ESGL.LSLQQSSLGKCndSDISLLSSGYAGDEENSEVSLL.GSTPI.LRLQR.RLLTQAGSAPTSQLCAIYSPSQIR.NQL.ASQAHSIKQTGGE...........
A0A2Y9HWY9_NEOSC/102-258             .............LDKPDQLPPTFLEGRNGESAAW..NVQGQAPSLPAPSVEP.....QPPAWPHHDTGATQEPLRVSRGNLGNPWSS...ESGL.LSLRQSSQGKCkeSDTSLLSSGYAGDEENSEVSLV.GNTPI.LRLPR.RLHTQAGSAPRSQLCAIYAPSQIR.SQV.ASQARGSRQAGGE...........
L5M9B6_MYODS/14-171                  .........lavq----SSKQPSFAEDRKGDSCDW..NVQGQDVSLQPPYLEC.....QPPLRPCHDTGATPEPLKVPGSNLGPAWSSrssDSSL.RSVRQGSLQKG..GHISQRSSGYAGDEENSEVSLV.GGKRT.LQLSR.RLGTQAIVTQTSQLCAAYRPDQLK.SPA.ASPAPSAPQPGGE...........
A0A2Y9RXE0_TRIMA/18-174              .............LDKQIQLPSIFLQEGKGESSARdaNAQGQDPSLQSPRLEL.....QSHAWPCHNAGAPQEPQKSSYSDLGSIRTS...DSYV.SSMRHLSPEKC..SNVSLASSGYAADKENSEVSLV.DSGRV.SRLSR.RLSNQVGSTQTSHLCATYSSIQLK.SLQ.TGQADNSKQTGGE...........
A0A5N4CXI1_CAMDR/1-116               .......maapat----------------------..----------------.....-------NASGATQEPLRGFGGHLGNTWSS...GSDV.PSLRHSSREEC..SDVSRLSSGYAGDEESSEVSLL.GSRRI.VQLNR.RLHIQAGGAQTSQVCATYSPNQLK.SRL.ASQADSTVQTGGE...........
A0A5F5XUX6_FELCA/89-230              .............LDKPDPLSLTFLQGTTGQSAAW..NAQDQAPGLPSPSLEP.....QSPAWPHHDAGATQGPLRLPGSNLGNAWRR...ESDL.LSPRQSSLGTCgdSDTSLLDSGYAGDEENSEVSLV.AKRHI.VRLHR.SLNTQTDSAQSSQLSS--------.---.-------------geastsrgw..
A0A5F9ZHF3_HUMAN/1-153               .............LDKPLQLPPIFLEGEKGESSVQ..NEQEGEPSLQSPSLEL.....QSPAWPRH-AGVAQEPLKVSSSYLSDTQSS...ESHV.SSVQHPRPEEG..SHAS-LSSGYAGDKEGSDISLV.GSHRR.VRLNR.RLNTQAASNQTSQLGSIDPPSSLK.SRL.TGPAHSTKQTGG-k..........
A0A2I3GGE4_NOMLE/48-200              .............LDKPLQLPPIFLKGEKGESSVQ..NEQEGEPSPQSPSLEL.....QSPAWPHH-AGAAQEPLKVSSSNLSDTQSS...ESHV.SSVQHPRPEEG..SHAS-LSSGYAGDKDGSDISLV.GSHRR.VRLNR.RLNTQAASNQTSQLGSTDPPNSLK.SRL.TSPAHSTKQTGG-r..........
A0A1U7U177_CARSF/66-192              .............LDKSIQLPPVFLEKEKGETSAW..SAQGQEPSLESPSLQR.....PSHAQT-HHAGTSQEPLKLSCNDLGDTPSR...ESHV.SSER----EEC..SHASLLSSGYSGDEESSQVSVP.GGRRV.VRVNRrRLPIRAVSTQTS------------.---.-------------segp.......
A0A384BN70_URSMA/83-239              .............LDKPDQLPPTFLQGRNRESAAW..NVRGQAPSLPAPSVEP.....QAPERPHHDTGATQEPLKVLGGNLGSPWNS...DSSL.LSLRQSSLGKCreSVTSLVSSGYAGDEENSEVSLV.GSTPM.LRLQR.RLHTQAGSAPTSQLCAIYSPSQIR.SRL.ASQARGTKQPGGE...........
A0A1U7RKJ5_MESAU/26-179              .............LDKPIPLPPTIKV-EKGGSSVW..NAQEQRPSPSLPKLEF.....QPHVE-SSNSATIQKPLRIVYSTLGTPHSL...ESLK.KSTQHLKTEAC..SISTLSSSGYSADEESSKASLV.KSKQT.VRLTK.RLTTQVNSTQSSEQSIKSSPGALKiRRL.KSQGQDTQQAGGE...........
A0A452CJX7_BALAS/63-219              .............LEKPSQPPPASLQGRQGESPAW..NAQGQGPGLQPPSLEP.....PSPARPCNDTGATQEPLRDSGGDLGNTWSH...ESNVpPSPQHSSLERC..SDISRLSSGYAGDEESSEVSLLgGSSRI.VRLNR.SLRTQAGGAQTSQVCATYSPNQLK.SRL.ASQADSTVQTGRE...........
A0A3Q2I1T9_HORSE/51-202              .............LEKPTQVPPTLLQDRKGDAFTW..DAQSQDPSLQSPGLEP.....QPPVGLCQDARATQDPPRASRGNLGSVRSK...ESSV.TS---CSLEKC..SNVSRLSSGYAGDEENSKVSLR.GSRRI.VRLKR.RLNTQAAGAQISQPCATFSRSQLQ.SQL.ASQANSTTQTGG-k..........
A0A2R8ZDF8_PANPA/64-216              .............LDKPLQLPPIFLEGEKGESSVQ..NEQEGEPSLQSPSLEL.....QSPAWPRH-AGAAQEPLKVSSSYLSDTQSS...ESHV.SSVQHPRPEEG..SHAS-LSSGYAGDKEGSDISLV.GSHRR.VRLNR.RLNTQAASNQTSQLGSTDPPSSLK.SRL.TGPAHSTKQTGG-k..........
E1BNX5_BOVIN/1-156                   .............LEKPSQLPPTFLQGKQGESPSG..EAQETGAGLQSASLEP.....QSPAWPRHDAEATQEPLRDSSGHLGNTVSH...ESSVlSSLQHSSLEQC..IDISRLSSGYAGDEENSKVSLP.GSHQI.VRLSR.RLHTQAGGAQNSQVCAVYSPKQLK.RRL.AHQAKGTKQTGRE...........
A0A2I2YW75_GORGO/64-216              .............LDKPLQLPPIFLEGEKGESSVQ..NEQEGEPSLQSPSLEL.....QSPAWPRH-AGAAQEPLKVSSSYLSDTQSS...ESHV.SSMQHPRPEEG..SHAS-LSSGYAGDKEGSDISLV.GSHRR.VRLNR.RLNTQAASNQTSQLGSTDPPSSLK.SRL.TGPAHSTKQTGG-k..........
A0A2U3Z969_LEPWE/102-255             .............LDKPDQLPPTFLEGRNGESAAW..NVQGQAPSLPAPSVEP.....QPPAWPHHDTGATQEPLRVSRGNLGNPWSS...ESGL.LSLRQSSQGKCkaSDTSLLSSGYAGDEENSEVSLV.GNTPI.LRLPR.RLHTQAGSAPRSQLXA---PSQIR.SQV.AGQARGSRQAGGE...........
W5QBI8_SHEEP/61-221                  .............LEKPSQLPPTFLQGRQGEPPRG..EAQEAGAGLQSPSLEPqnhepQPPAWPRHDAEATQEPLRDSSGHLGNTVSH...ESSVlSSLQHSSLVQC..IDISRLSSGYAGDEENSEVSLP.GSHQI.VRLSR.RLHTQAGGAQNSQVCAIYSPKQLK.RRL.ARQAKTTKQSGRE...........
A0A2Y9L7D5_ENHLU/11-167              .............LDKPDQLPPTFLQGRNGESAAW..DVQDQAPGLPAPSVEP.....QPPAWPHHDTGATPGPLRLSGGNLGNSWNS...ESGL.LSLRQPSEGKCraSDASLLSSGYAGDKENSEVSLV.GGTPI.LRLQR.RLHAPAVSTPTSQLCAVYSPNQIR.SRL.ASRACSSKQPGAE...........
H2NQG5_PONAB/64-216                  .............LDKPLQLLPIFLEGEKGESSVQ..NEQEGEPSLQSPSLEL.....QSPSWPHH-AGAAQEPLKVSGSNLSDTQSS...ESHV.SSVQHPRPEEG..SHAS-LSSGYAGDKEGSNISLV.GSHRR.VRLNR.RLNAQAASNQTSQLGSTDPPSSLK.SRL.TGPAHSTKQTGG-k..........
S9XWW7_CAMFR/10-128                  epqgrqpglvcgp----------------------..----------------.....----------RATQEPLRGFGGHLGNTWSS...GSDV.PSLRHSSREEC..SDVSRLSSGYAGDEESSEVSLL.GSRRI.VQLNR.RLHIQAGGAQTSQVCATYSPNQLK.SRL.ASQADSTA-----ssyq.......
A0A1S3ET74_DIPOR/103-257             .............LEKSIHLSPTCPEAGKGVSSAE..NAQRQEPSLLGLSLQL.....QPHPRPRHAAD-PEEPVSVSRSTLGQSQSS...KSQV.PSTEHSTPKEC..SNTSLLSSGYSGDEESSQVGLK.SRGRSrVPLSK.RLRAQLGSTQSSQVCVVNSPRSRR.HQL.NGQGLGLKQV---ssg........
A0A2K5R2S5_CEBCA/45-197              .............LDKPLQLPPIFLKGEKGESSVR..NAQEGEPSLQSPSLEP.....RPPAWPR-SAGAAQEPRKVSSSNLSFTQSS...ESHV.SSVQHPGPEDC..SHAS-LSSGYAGDKEGSDISLV.GSRRR.VRLNR.RLNNPAPSTQTSQLGSTDSPSCLK.SRL.TGPAHSTKQTGG-q..........
TNT_HUMAN/64-216                     .............LDKPLQLPPIFLEGEKGESSVQ..NEQEGEPSLQSPSLEL.....QSPAWPRH-AGVAQEPLKVSSSYLSDTQSS...ESHV.SSVQHPRPEEG..SHAS-LSSGYAGDKEGSDISLV.GSHRR.VRLNR.RLNTQAASNQTSQLGSIDPPSSLK.SRL.TGPAHSTKQTGG-k..........
A0A091DR12_FUKDA/1-127               ...........mp------LPPIVPKAEEGGSSAC..GALGEEPSPWSPSLEL.....QPRQQPSYAA-VVRESLRVSGSTLANPRSR...QSLV.HSMLYPRLKDQ..SSSSLGSSGYAGDEESSSTSLV.RGRRI.KRLTR.RLNTQAKAPAPS------------.---.-------------klegk......
A0A4W2DP33_BOBOX/65-220              .............LEKPSQLPPTFLQGKQGESPSG..EAQETGAGLQSASLEP.....QSPAWPRHDAEATQEPLRDSSGHLGNTVSH...ESSVlSSLQHSSLEQC..IDISRLSSGYAGDEENSKVSLP.GSHQI.VRLSR.RLHTQAGGAQNSQVCAVYSPKQLK.RRL.AHQAKGTKQTGRE...........
A0A2U3ZCJ0_ODORO/57-213              .............LDKPDQLPPTFLQGRNGESAAS..NVQGQAPSLPAPSVEP.....QPLAWPHHDTGATQEPLRVSRGNLGNPWSS...ESGL.LSLRQSSQGKWkeSDTSLLSSGYAGDEENSEVSLV.ANTPN.LRLPR.RLHTQAGSAPSSQLCTIYSPSQIR.SRV.ASQACGSRQAGEE...........
A0A5F8A729_MACMU/1-153               .............LDKPLQLPPIFLKGEKGESSVR..HEEEGEPSLQSPGLEL.....QSPEWPHH-AGAAQDPLKVASSNLSDTQSS...ESHV.SSVQHPRPEEC..SHTS-LSSGYAGDKEDSGTSLA.GSHRR.VRLNR.RLNTQAASNQTSQLGSTDPLRSLK.SQL.TGPAHSTKQTGGE...........
A0A2I3RAY8_PANTR/64-216              .............LDKPLQLPPIFLEGEKGESSVQ..NEQEGEPSLQSPSLEL.....QSPAWPRH-AGAAQEPLKVSSSYLSDTQSS...ESHV.SSVQHPRPEEG..SHAS-LSSGYAGDKEGSDISLV.GSHRR.VRLNR.RLNTQAASNQTSQLGSTDPPSSLK.SRL.TGPAHSTKQTGG-k..........
A0A1A6GXB1_NEOLE/75-228              .............LDKPIPLPPAI-KAEKGGSSIW..NAEEQNPKPSLPSLEL.....QPLVG-SGRAATIQKPLRIVYSTLGTPHSI...ESLK.KSTQHFKPEAC..SISTLLSSGYAADEESSKASLD.NSKRI.VRLTK.HLTTQVDSTQSSELGITSSPSASKtRRL.NSQGQHTQQAGGE...........
L8I8Q6_9CETA/1-156                   .............LEKPSQLPPTFLQGKQGESPSG..EAQETGAGLQSASLEP.....QSPAWPRHDAEATQEPLRDSSGHLGNTVSH...ESSVlSSLQHSSLEQC..IDISRLSSGYAGDEENSKVSLP.GSHQI.VRLSR.RLHTQAGGAQNSQVCAVYSPKQLK.RRL.AHQAKGTKQTGRE...........
G3U887_LOXAF/48-202                  .............LDKQTQLASIFLQEGKGESPAW..DAQGQDPNLQSPCLEL.....QSHAWPCHNTGTPQDLLKSSCSDLRGIRSS...ESDV.SSMRHLSPGKC..SSISLASSGYVGDKENSEVSLV.GSGRV.SRLSR.GLSNQAGSTQTNHLCATYSSVQLK.GRQ.TGQANSCKQTGGE...........
A0A3Q7XAA5_URSAR/16-172              .............LDKPDQLPPTFLQGRNRESAAW..NVRGQAPSLPAPSVEP.....QAPEGPHHDTGATQEPLKVLGGNLGSPWNS...DSSL.LSLRQSSLGKCreSVTSLVSSGYAGDEENSEVSLV.GSTPM.LRLQR.RLHTQAGSAPTSQLCAIYSPSQIR.SRL.ASQARGTKQPGGE...........
A0A0D9SBY7_CHLSB/63-215              .............LDKPLQLPPIFLKGEKGESSVQ..NEEEGEPSLQSPGLEL.....QSPEWPHH-AGAAQDPLKVASSNLSDTQSS...ESHV.SSVQHPRPEEC..SHTS-LSSGYAGDKEDSSTSLA.GSHRR.VRLNR.RLNTQAASNQTSQLGSTDPLRSLK.SQL.TGPAHSTKQTGGE...........
D3Z9W1_RAT/26-176                    .............LDKPIPLPPAIKAEKRGSS-VC..NAQEQKSSSSLSSLEN.....QLHVGSCHSA-IIQKPLKIVCSTLGTPEST...ESLK.KSTQSLEPKVC..SISTLSNSGYEADEESSKDNLV.NRKQT.VRLTK.RLAARVES---SELFPVPHLSPFK.NRRpARKGQCTQKSGG-e..........
A0A2Y9FWY6_PHYMC/64-219              .............LEKPSQPPPAFLQGRQGESPAW..NAQGQGPGLQPPSLEP.....PSPAWPRNDTGATQEPLRDSGGDLGNTWSR...ESDMpPSLQHSSLERC..SDISRLSSGYAGDEENSEVSLL.GGSRI.VRLNR.RLRAQAGGHQTSQVCAIYSPNQLK.SRL.ASQADSTVQTGRE...........
#=GC seq_cons                        .............LDKP.QLPPhFLpGcpGESush..NsQtptPSLpuPSLE......QsPsWP+HsuGAsQEPL+lSuusLGsshSS...ESpV.sSlpHso.-cC..ScsShLSSGYAGDEEsS-VSLl.GS++h.VRLsR.RLpTQAuSsQTSQLsus.sPspLK.uRL.supAcuT+QoGG............
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