GenomeNet

Database: Pfam
Entry: DUF530
LinkDB: DUF530
Original site: DUF530 
#=GF ID   DUF530
#=GF AC   PF04409.12
#=GF DE   Protein of unknown function (DUF530)
#=GF AU   Waterfield DI;0000-0003-2885-5126
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   COG1771
#=GF GA   20.80 20.80;
#=GF TC   20.80 21.30;
#=GF NC   20.20 20.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR007503;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Family of hypothetical archaeal proteins.
#=GF SQ   61
#=GS Q2NI37_METST/1-534        AC Q2NI37.1
#=GS A0A125RCR3_9EURY/1-524    AC A0A125RCR3.1
#=GS A5UJ97_METS3/1-524        AC A5UJ97.1
#=GS A0A218P8Q0_9EURY/2-265    AC A0A218P8Q0.1
#=GS A0A160VX47_9EURY/3-261    AC A0A160VX47.1
#=GS A0A075LTW2_9EURY/2-262    AC A0A075LTW2.1
#=GS Y1110_METJA/1-133         AC Q58510.1
#=GS Q5JH83_THEKO/2-262        AC Q5JH83.1
#=GS O59210_PYRHO/3-264        AC O59210.1
#=GS W0I6J3_9EURY/2-263        AC W0I6J3.1
#=GS D3E2Q0_METRM/1-524        AC D3E2Q0.1
#=GS B6YVS7_THEON/2-261        AC B6YVS7.1
#=GS A0A165Z804_9EURY/1-522    AC A0A165Z804.1
#=GS A0A166CT68_9EURY/1-521    AC A0A166CT68.1
#=GS G0HKR8_THES4/2-266        AC G0HKR8.1
#=GS A6UUW6_META3/1-127        AC A6UUW6.1
#=GS A0A218P3R9_THECE/2-266    AC A0A218P3R9.1
#=GS A0A150JJH8_9EURY/1-189    AC A0A150JJH8.1
#=GS A0A2A2HDG4_9EURY/1-537    AC A0A2A2HDG4.1
#=GS A0A166BU97_9EURY/1-524    AC A0A166BU97.1
#=GS A0A2H9L0Z6_9ARCH/4-112    AC A0A2H9L0Z6.1
#=GS O26688_METTH/1-523        AC O26688.1
#=GS U6EDN4_9EURY/1-520        AC U6EDN4.1
#=GS F6D2K7_METPW/1-522        AC F6D2K7.1
#=GS F0T7L5_METLA/1-521        AC F0T7L5.1
#=GS R9SJH8_9EURY/1-518        AC R9SJH8.1
#=GS A0A150J0A1_9EURY/204-326  AC A0A150J0A1.1
#=GS E3GYM4_METFV/1-511        AC E3GYM4.1
#=GS A6UUW6_META3/124-482      AC A6UUW6.1
#=GS A0A1D2W9J9_9EURY/1-522    AC A0A1D2W9J9.1
#=GS D7DTU5_METV3/55-170       AC D7DTU5.1
#=GS Q8U0L0_PYRFU/3-261        AC Q8U0L0.1
#=GS C5A6R7_THEGJ/2-266        AC C5A6R7.1
#=GS A0A1J4UFL3_9ARCH/20-110   AC A0A1J4UFL3.1
#=GS A0A1Z2TMB0_9EURY/2-266    AC A0A1Z2TMB0.1
#=GS D5VU28_METIM/115-471      AC D5VU28.1
#=GS A0A100XYU5_9EURY/2-266    AC A0A100XYU5.1
#=GS Q6LYP0_METMP/1-123        AC Q6LYP0.1
#=GS D7DTU5_METV3/166-519      AC D7DTU5.1
#=GS A0A150JJH8_9EURY/231-347  AC A0A150JJH8.1
#=GS F6BA65_METIK/120-477      AC F6BA65.1
#=GS A0A150J0A1_9EURY/1-184    AC A0A150J0A1.1
#=GS A0A1D2X4J9_9EURY/1-534    AC A0A1D2X4J9.1
#=GS A0A117KQB5_9EURY/2-261    AC A0A117KQB5.1
#=GS A0A1D2WKW1_9EURY/1-524    AC A0A1D2WKW1.1
#=GS A0A1V6N2R0_9EURY/1-546    AC A0A1V6N2R0.1
#=GS A0A150J220_9EURY/1-189    AC A0A150J220.1
#=GS A0A219AMZ2_9EURY/1-518    AC A0A219AMZ2.1
#=GS A0A150J6J7_9EURY/228-380  AC A0A150J6J7.1
#=GS A0A0U3DQW0_9EURY/1-524    AC A0A0U3DQW0.1
#=GS A0A166D262_9EURY/1-522    AC A0A166D262.1
#=GS F8AGY3_PYRYC/3-261        AC F8AGY3.1
#=GS A0A2H9L0Z6_9ARCH/104-438  AC A0A2H9L0Z6.1
#=GS Q6LYP0_METMP/119-474      AC Q6LYP0.1
#=GS A0A1D3L1I3_9EURY/1-521    AC A0A1D3L1I3.1
#=GS A0A1J4UFL3_9ARCH/106-434  AC A0A1J4UFL3.1
#=GS Y1110_METJA/127-484       AC Q58510.1
#=GS D5VU28_METIM/1-120        AC D5VU28.1
#=GS C6A3G2_THESM/3-265        AC C6A3G2.1
#=GS A0A150J6J7_9EURY/1-187    AC A0A150J6J7.1
#=GS F6BA65_METIK/1-126        AC F6BA65.1
Q2NI37_METST/1-534                   .................................................................................m--SDILVTQSEKFLKTIQSKPVIAESI........EDFDSFIKIY.SYLNSNLKQLQNIRNKMEIR.GFTSPYSALKRYskgGNSSNPEIIPDDVHDQSRHAQYFRIKASNKKNILDQVKSAIASHKIAIGHLE.EYVELECKKCGQKYKK..KTLEDilvy................denevES.CKCECGS.SEFKFDSDMSGICRLELIKYLPLGGEYLLKRSQLTNYSLEAYRKIIKIMKQEKRGRVK..S..IT..V..IAKIK..D.EntGKWVSRKMNIDYADESNYELELRKRYGPNVRIELLQFHHKKPSLINDKYVQNALAIAYLHYSENIVSKKIDEIIPKHIHNMKK..IDTYNSVLNEARKDAGR..LAREAE....ERIE..LEEELTYVKLRKVNLITKDHK...LDRELKEDLNKESEIKKHYYIETPFILILWDIFKYYLTTSENRRNNYSGPFPNLRPTLDSNQIK...VFEN..iFPKDVIE...L...LQDS-GENIDTIPNMKET.........IQY.K.LDLETKRKKLHLKSNHAAYGAIALNSKS.NISLNKAADLLYV..DKDEAAKEKAALQKIE...KPS...TNKAKKFLEIIN...............................................................
A0A125RCR3_9EURY/1-524               ..................................................................................MQESVLVNRAESYLKEISNDSISLENI........EDFENFKSLY.FKLDDRLNHLQKLKDDMDAQ.GYTTPFTALNKY...GTKSVSDVVVEEVGESSRHNQIFRMKANAKKNILDRVKSAIDSHKIAIGNLN.QFGYLKCNSCYKKYTI..DEYKQ.........................ME.SKCSCGS.KGFTFKIKKEATYRVEIIPYLPLSGNYMVLRSELCGYGKESFKKVLNILKQERKGVVN..T..VS..L..VIKFR..DkN..NRLIRKNITLGSEFVNSYEEEVRRIYGTNVRIEVLRLNRTKPAIIDDKHARTALALAYVRYAEEIIENIKEDILKRNLTDFKR..LNKYFEVISEYENQTPD..YIDKYDl..dAIDS..WRKSKIEEEFIKFGYFDKFGK...MKRSLRRDLKVRDNIYKNTFVNIAATLIIWDIFRYYLTTSNNSRRIENGPFPYIRVELDREQRK...VFQM...DYTDIIE...T...LNNFTDIKIIPVPEMDLL.........LYE.K.FQFEKQIRNSNIQFNYVALGAALIYENS.NIPLENISNAFNI..NESRIKKEIKHIDHIK...NPK...SDKSKRFLELIK...............................................................
A5UJ97_METS3/1-524                   ..................................................................................MEESALVAKAEKYLKEISNDSIRLDNI........EEFENFKRLY.YKLDDRLNSLQELKESMDAQ.GYTTPFTSLNKY...GTKAIAEVSLEEMSENSRHNQMFRMKANAKKNVLDRVKSAIDAHKIAIGHLE.QCGYLKCDSCYKKYSL..SEFRL.........................KG.EKCSCGH.ENFSFKINKDATYRLEIIPYLPLSGNYLVLMSELSGYGRNSFKKVLNILKQERKGLVK..T..IS..L..VIRFR.dE.N..GRWIRKNVTLDSEYISNYEEEVRNRYGKDVRIEVLRFHRTKPAIIDDKYVRNALAISYVKYSEDIISSIKDSILKRKLSDFKR..INKYDAIRYKYENEIPG..FIEEYDi..gELES..WRQSKITEEFEKLHFIDKFGN...YNRSLKRDLKIRENIEKTIFENMAPTLMMWDIFRYYLTTSHNNRKISNGPFPYIRAELDRQQRK...VFQT...TFKKVIK...V...LNEFTDLKIISIPDMDLI.........LYE.K.FKFEKQSKNSNILFNYPALGAGLIHEHG.NIEIETIGNVLNI..NDSKIKKELKNINHIR...KPK...SAKSKKFLDLIK...............................................................
A0A218P8Q0_9EURY/2-265               ...............................................................................ttt---EELVAQVNKILDDI---GIDMDGL........FETFDIPSIS.LRLKENLSLLQELEEDLSK-.----------RV...GEA-TPSADFSDRKNRDPHIQWIYKKKRNRILALERLRSAITAHKMALALIS.ANY--TFFLGKKLITI..KELT-.........................--.---RENA.ENVKAVSNPIQLGRVEVLPYLAYSGDVLRLLSRESIAVRESFKLIKGKLR--EKGTVR..T..RG..L..RIEVEywE.N..NRLKKARLDLPTD--ADIEAELRQRYGRRFRWRVLSFVKTKGVLINNHYTVDNLALAYS------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------ildpedgakk.....................................................
A0A160VX47_9EURY/3-261               ......................................................tteeliarinktlddiaidtpglfddld---------------------------........-----VPKLF.FVFKNRLEVLKDLEEELERR.--------VGEL...GPA----PIFKDKKSKDPHLSWIYRKRHYRSLTLERLRAAITAHRMALAILD.ANYVL------RKGKV..DIPPD.........................AL.KRSDLQK.--VKAVERPVKLGRIDILPYLAYSGDVLRLLGQRGIEIREHFKLIKGKLREEGTVRKE..K..FR..I..EVEYW..E.N..GKLKKEKLDLPVD--ADIEGELRKKYGKRFRWRVLSYVKTVGVLINNHYTVDNLALAYSTL----------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------npke...........................................................
A0A075LTW2_9EURY/2-262               ..............................................................................ttte----ELISRVNLLLDDIKTNTPRLF--........--EGSVPSIV.FHLNKQLSVLEDLRHELERRvGVTAPSTYFLSR...SER---DP---NI-----H-WIYR-KKHNRVLALERIKSAIMAHKMALGHIL.A--NYSFYDGRKEIEP..KNIK-.........................DP.KKVRAIK.-------KEIVIGRLDILPHLAYSGDVLRILSQKDVVVREAFKNIKGKLR--ERGTLK..K..IGyrL..EVEYF..E.N..KKLKTTRITLPED--VDIDSELRRRYGKMVRWKVLTSVKTRGVLINNHYTVDNLALAYASLNPEK------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------alqm...........................................................
Y1110_METJA/1-133                    ...............................................................................mes--TSNLIKNANEFLDSLNEINDKLKEVvgkiknktIDKTKLSDII.LTLEKNLEILQDLKSKMEFL.EFDSPYKNVGKL...KG----GYDSEGLQEIASYSTYLRRIASEKKGILERVRHALVAHKIALAHLT.E---------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------dignin.........................................................
Q5JH83_THEKO/2-262                   ..............................................................................ttte----ELVAQVNKILDDI---GIDLGEL.......fQDFDPV-RLA.LTLNRNLSLLEELEEELERR.--------VGEG...----GPSVPMGDRKNRDPHLQWLYRKRHYRTLALERLRSAITAHKIALAILD.A-----------NYTF..KRGSS.........................EI.KATEIKD.EKVKATRKPYSIGRVEILPYLAYSGDVLKLLARESLSVRDAFKEIKGRLREQGMVKTR..S..IR..L..EVEYF..E.N..NRLKKAHVSLPAD--ADIEAELRKQFGRRFRWRVLSLVKTRGVLINNHYTVDNLALAYASFN---------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------pekgael........................................................
O59210_PYRHO/3-264                   ................................................................................tt---EELIARINKILDDIS---IDIPGL........FEDLDIPKIF.LTLKDQLESLKELEEELERR.--------VGEL...GPT----PIIKEKRSKDPHLSWIYRKRHYRILTLERLRSAITAHRIALAILN.ANYTLK------KGKS..EISPE.........................SL.KKSDLGK.--VKVIEKELQLGRVEILPYLAYSGDVLKLLGQRGIEVRESFKDIKSRLREE--GVVR..KerFR..I..EVEYW..E.E..GKLKKEKLDLPID--ADIEEELRKRFGKRFRWRVLSYIKTLGVLINNHYTVDNLALAYATY----------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------dpkrgse........................................................
W0I6J3_9EURY/2-263                   .............................................................................tttee-----LVAQVNKILDDIG---IDMAGL.......fESFD-ILSLV.FHLNRNIEILRDFEEELSRR.-----------V...GET-VPSVRGLDKKEKDPHIRWLYKKKHNRILALERLRSAIVAHKMALALIS.A--NYSFYIGNKEIDV..KTIKK.........................HE.---EL--.RRIRVVKKPVILGRLEILPHLAYSGDVLKLLGQESVEAREAFKLIKAKLR--EKGVVR..K..KS..F..RIEVEywE.S..GRLKKTRLDIPTD--ADIESELRKRFGKRFRWRVLSYVKTKGVLINNHYTVDNLALAYATF----------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------dperg..........................................................
D3E2Q0_METRM/1-524                   ..................................................................................MDESLMITESEKFLNQIEREKLDLTNLks....dfSDLESYLEVY.ELLKSNFDKLQDMKESMDER.GYTAPFRSLNRY...GSRVSEDVDYEELGELNRHNTIFRNNASAKKNSFDRVKYAIAAHRIALGNLE.EYAKIRCKDCQKSYKV..STFLE.........................NS.KTCKCGS.TDFELKVNHSGIHRLEIIPYLPLSGNYMVLLSSLSGWGRDSFRRILNILQQKRKGVVK..T..VT..P..IIRIK..E.N..GRTITKRVNLDSEFADCYEEELRRIYGKGVRIERLEFHSTKPTIVNDKYTRTNLALAYVKHAEDIVSRHEEEIFEENIKDLNN..LKTYDELIYSVNLEKPE..YMDEDD....-LDS..WREQKIQDNLLELGLMDKYGH...LDKQLKKDLKERERIKSKIFADIAPTLILWDISKYYLCTSYDRRKRYGSPFPFIRNDLDRQQRK...VFAN...PHANVVG...L...LREKEKKHMIAIDEMDLL.........LYK.K.FKLEKRIKNTNFKLNYAALGPAIVFANS.DYNIKEVSRAYKV..GEKSVKREIMNIKSFR...KPN...SKKSREFLGKIK...............................................................
B6YVS7_THEON/2-261                   ...............................................................................ttt---EELVAQVNKILDDI---GIDMDGL........FETFDVPSIS.YRLKENLSLLQELEEDLSRRvGEATP--SVGGF...DK-----------RNKDPHIQWIYKKKRNRVLALERLRSAITAHKMALALIA.A--NYTFTLGKRELSI..RELKR........................eDI.PKVKAIQ.-------KPVQLGRVEVLPYLAYSGDVLRLLARESIEVREAFKFIKGKLR--EKGTVR..T..RG..L..RIEVEywE.N..NRLKKARIDLPTD--ADIEAELRQRYGRRFRWRVLSFVKTKGVLINNHYTVDNLALAYS------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------vldpek.........................................................
A0A165Z804_9EURY/1-522               ..................................................................................MEETSLIKKAESYLNKIANKRIDLSNV........SKLDNFINIY.QSFTQSLDVLVEMKSDMEMR.GYMSPYSSLTKY...GAPMSNEVHYDELAEISRHGQSVRRCATAKKIILDRIKSAIDSHKIAIAHLE.EYALINCNSCYNEYKL..SEFLI........................lKE.KKCSCNC.SNFSISPNQNTVYRLDIIPYLPLSGNYMVLRAQLSHWGRKAYTKIVNSLSKKKKAVVK..T..VS..L..AIKYN..K.D..GRWLTKNLNLDSDYVDLYEEKIKELYGKDAKILRLNFNHSNPSIINDKHTITALALAYSQLSQEIVKKNSSSILKENISDYNS..LKSYDNIIFSIKNEQPR..FIVDEN....SLEE..WRDLKIKDSLKDKGLMDKSFK...LNPKLKKDLYSREQLENRIFSEIGNVLILWDIFKYYLTTSNDRRKRYKGLFPYLRGDIDRTQRE...VFAN...YNPKTID...L...LVKYGCEKILKIKDMDLI.........LFE.K.FKLEKKIKGLNMNFNYLFLGAALISLNS.NLDWEIIEENFNI..NSEKIKKGIEDINMIN...QPR...SDKSKKFLGLV-s..............................................................
A0A166CT68_9EURY/1-521               ..................................................................................MDESSLISKTEKYLVKIQNEKIDLESI........SKLEVFKSVY.SRFTYRLDKLQNMKGSMDAK.GYTAPYRSLSKY...GSNVSGDVAFEELNEVNRHSQYFRMKATAKKNILDRVKSAIDAHKIAIGHLD.EYAIFKCKSCSKTYRP..SKFFE.........................IN.ERCSCNC.ENFEFVINHTGVYHLEIIPYLPLSGNYMVLMLELSSWGRESFKKVLNILKQERKGVVK..T..VS..V..VIKFM..E.N..ERWIRKRVALESEHVDNYEEEIRKRYGNNVRIEFLQFHRTKPTIINDKHARTALALGYVKYSEDIINQNKAAILKERIKDVSK..LNTYDQIITEVKLEKPN..FIEGEE....SLKE..WQELESENRLKKAGFIDKNGK...LDQELLRNIGKKRAIEKNIFSDLASTLILWDIFKYYLTTSNDRRKRHGGPFPYLRGDLDRQQRK...IFEN...LNKNVVE...I...LKTMANQKILEVKNMDLL.........LHK.K.FNLEKKIKNSNIMINYTALGAAIISSNC.NIPISISADTFNV..SKDSVKKELKNIETIN...TPK...TNKSKKFLELIK...............................................................
G0HKR8_THES4/2-266                   ..............................................................................ttte----ELVAQVNKILDDI---GIDMDGL........FETFDIPSIS.FRLKENLSLLRELEDDLSRRvGETTPSAG----...---------FSDKKNKDPHIQWIYKKKRNRVLALERLRSAITAHKMALALIS.AN--YTFFMGKKLVSL..RELT-.........................--.---RENV.ERIKAVPNPVQLGRVEVLPHFAYSGDVLRLLARESVDVRESFKFIKGKLRE--KGTVRnrG..IR..I..EVEYW..E.N..NRLKKARLDLPTD--ADIEAELRQRYGRRFRWRVLSFVKTRGVLINNHYTVDNLALAYS------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------ildpengarkl....................................................
A6UUW6_META3/1-127                   ................................................................................me-DSSSLIKRCNEYLTELQQFREYLLELran..ktnIDKSTYDEIT.NKLKENLEILEDLKEKMEIC.GFDTPYMGVGTL...-----KGCDDSDIYEIKNYSSHLRRMVDEKKGALERVRYAIISHKMAIGNLS.D---------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------dag............................................................
A0A218P3R9_THECE/2-266               ..............................................................................ttte----ELVAQVNKVLDDI---GIDMDGL........FETFDVSSIS.YRLGENLSLLQGLEEELSRRvGEVTP--STGGM...GKR-----------DRDPHLQWIYKKKRNRVLALERLRAAITAHKMALALIE.ANYTF--FIGRRPISP..KELTR.........................--.--ENVG-.-DVEAVPRNVRLGRVEILPHLAYSGDVLRLLARESVDVRESFKFIKGKLR--EKGTVR..T..RG..L..RIEVEywE.N..NRLKKARIDLPAD--ADIEVELRKRYGRRLRWRVLSFVKTRGVLINNHYTVNNLALAYSV-----------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------ldpkngvekl.....................................................
A0A150JJH8_9EURY/1-189               ................................................................................ms-----LISRISSYLDTLKY-SINPEKL........RDSEYFLSTY.LKLKKDYEELISIRRKIEFL.GYQNPYFVIKGI...--K--------DAQ-----DPYFRKRAMEKKICFDNIQHAIAAHRIAIGQLV.D--AMGFEKDGIIYTG..HEAIK.........................FT.EEGGMGK.----FIFSPDGVYRLDIFKYLSFSGEYMKTLFSLSKEERENYRKIMEILGEKSKGKSS..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------tkkri..........................................................
A0A2A2HDG4_9EURY/1-537               .................................................................................m--SEFLVTQSEKFLKQIQKKPVIAESI........EDFEGFFENY.SYLKSNLKKLQITRNKMEIR.GFTSPYSALKRYgkgNSSNNGDIIPDDVYDQSRHAQYFHTKASNKKNILDQVKSAIASHKIAIGHLE.EYAQITCKKCGQKYKK..NTIEDilkyde.............deleviNH.ECSNCGS.SEFELSHNPNGIYRLELIKYLPLGGEYLLKRSQLTNYSLEAYRKIIKIMRQEKRGRVK..S..VT..V..IAKIK..D.EktGKWQSKKVNIDYADESNYELELRKRYGPNVRIELLQFHHKKPSLINDKYVQNALAIAYLQYSENIVNKEINNIIPRSISNMQR..IHTYNQLTEEARKDAGR..LAREAE....ERIE..LEEELQYVKLKKVNLMNKDHV...LDRNLQEDLKKQAEIKKHYYIETPNILILWDIFKYYLSTSETRRNNYAGPFPNLRATLDSNQLK...VFDN..vFAKDVVD...L...LKDN-DENIDVINNMKET.........MQY.K.RELENKSKNLHLKAPQQVYGAIALNNKT.NMSLNHAAELLYV..DPEEAAKEKASLQKIE...KPS...TNKAKKFLEIIN...............................................................
A0A166BU97_9EURY/1-524               ..................................................................................MEESALVVKAEKYLKKISKDEVTLDNI........DDFEVFKSLY.FKLDDRLNYLQNLKEAMDAQ.GYTTPFTSLTKY...GTKSLSEVTVEEVSENSRHNQIFRMRANAKKNILDRVKSAIDSHKIAIGHLN.QYGYVKCNSCYKKYSM..EEYKH.........................NF.GKCSCTS.ESFSFKINKEAVHRLEILPFLPLSGNYMVLMSQLSNYGRESLKMVLNILKQERKGVVK..T..IS..L..VIKFK.dE.N..KRLIRKSISLDSEYINNYEEEVRKRYGRNVRIEALRFHRTKPAIIDDKHARNALAISYVKYAESIISEIQDEIYKRKLSNFKQ..ITKYEEVILKYNNQAPD..YIDKYDv..dAIEE..WRRLQIEKNLRNLHLMDKFGN...LNRLLKRDLRIKENIQQSIFKNFAPSLILWDIFRYYLTTSKNSRKIRNGPFPYIRVELDRQQRK...IFQT...DYSKVIG...V...LNQFSDIKIIPIEEKDLL.........LYE.K.FKFEKQIKNSNIKFNNVALGAALIHLNS.DVDIEMISNAFNI..NESKIKKEIKNVDNIK...NPK...SDKSKKFLNLIK...............................................................
A0A2H9L0Z6_9ARCH/4-112               ............................................................slhlvsdannfldsvsaergda---------------------------........----------.---ANRLEKLNEFKARMIAN.GFNAPFGALMAS...AKE-AQKPGADEVADQKKHASYMRYVAKLKKFTLNRVRVAIAAHKMAQ----.----------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------aledanldemk....................................................
O26688_METTH/1-523                   ..................................................................................MNESGLIARSERFLESIKDRKVSLDDL........KSVEGFIDLY.TYLRGNLEELQDLKEAMELR.GFKYPFRSISGY...SSQYSPEI-AEDVHDIKRHAQYFRMKASTKKNLLDRVNSAISSHRIALGNLE.EYALLQCPDCSRSLRL..SEVEYqd.....................ilDG.VMCPCGS.GRMEIEFSGSAICRPEIIPHLPLSGDYMVKMSELSLWARKAFKKIMRLFKNEKKGAVR..S..AT..L..VIKVL..E.D..GRWIRRRITIDSDDN-DYERMLRQRYGPNVRIELIQFHRKKSSIINDRYTRTALALGYAGLSHDIIMDIKERVYSEKLRDYDA..VKRYRRILFEARTYSPD..LRLSED....ELQE..VRVQKMHDLLHEAGLGDSGGR...LNRELREDLEVMEEVKRELFRDVPVNLVLWDVALYYLGTSLDRRSKHAGPFPNLRPVLDRSQVR...TFDE...LSRDAVD...L...LNTCWEGGMVYIDKLGDV.........LLK.K.FEIEDKMKGLHMKPNPLAFGAAVLHMEG.EADIETCAEIFHV..RVEEVVEEKRNIENLG...KPS...TDRAKMFLNLIK...............................................................
U6EDN4_9EURY/1-520                   ..................................................................................MNESVLIGKSERFLDQIKRKEISLTDI........VSPEKFLSLY.TYLQNNLDSLHDMREIMEIK.GYTAPYRSINKY...GRPLTGETKAEDMYDISRHTQYFRMNAAAKKNILDRVKSAISSHKIAVGHLE.EFATLECSSCHKKYRG..HEIAL........................lTP.GKCECGQ.NDLKLHVNQEGVYRLGIIPFLPLSGDYMVKLSELSPRSREAFRRIVRILKQEKRGIVK..T..VS..L..IIKVM..E.D..NRWVRKRVTIDAQDDANYEKEIRSQYGPNARIEMMQFHRKKPSIINDKHMQTALSLGYVKYAENRILQFLPDLLEKTLHNKDK..VEEYQEAVEISKIKANK..Y-DTGD....DPES..LKNFYLKMELKDRGLLDKDGK...PEKTLQNDLKEKNLLEKSLFHEMPRIYILWDILRYYLTTSYDRRNKYSGPFPYLRPGLDTNQIK...AFQD...FEVEVVK...I...MQEYLSEDITYIPHMGRV.........LSK.K.FSVEKKMKGLHLQMG-PALGAALLSSEA.NIPVEKSAQLFSI..KVEDVSKGKETLSTLQ...RPT...SSRAKQFMAMMK...............................................................
F6D2K7_METPW/1-522                   ..................................................................................MNESGLIANAEKFLDGIKHERINADEI........PDFKTFMEIY.RYLKDNLDKLQDLRDTMEIK.GYKAPYRSILRY...GRQSSMEMKADDMYDISRHTHYFRMKAAAKKNILDRVKSAIASHKIALGHLE.EFAIISCSSCGKKFRG..HEISF........................iAF.KACECGC.NEFELSINKEGVYRLNIIKYLPLSGEYMVRMSELSPLGRDAFRKIVRIIKHEKRGIVK..T..LS..L..VVKVL..E.D..GKWVRKRVNLDATDQLNYEKEIRRKYGSNARIEFMQVHRKKPAIINDKHVQTAVSIAYVKLAEHNAREIFDTVLNNFISNKEK..LSFYDNALKTAKKRANR..IAEDID....DKED..LTNELLYKMLKDEKLINDKGN...RDKELEKDIKIRSKLEISLFVDMPQILILWDIIKYYLLTSYDRRSRYSGPFPNLRPSLDTNQMK...AFED...FDEFVVG...I...LRDYLAENIKYIPNIKSV.........VSK.K.FEIENKVKGLHVAINTPAAGAAILNTTG.KLSIEDSAHIFSV..NPAEVSKEVEKFKTFG...KPQ...TKKAKKFLEMVK...............................................................
F0T7L5_METLA/1-521                   ..................................................................................MNESVLIAKTEKFLDGIRRNPLKIDNI........NNFKDFINIY.HQLKNTLDDLLELRDTMEIK.GYKTPYKSLMKY...GRTSKSEMKVDDIYDVNKHTQYFRMNAAAKKNILDRVKSAIASHKIAIGHLE.EYAVFSCGNCGENING..HELET........................lVN.GNCKCGS.DQIQMKVNDQGIYRLEIINYLPLSGDYMVKMSELSPLGRDAFRRIVRSLKQEKRGIVK..T..VS..M..VIKVF..Q.G..DRWVRKRVNIDADDQMNYEREIRNKYGSDARIEFMQFHRKKPSLINDKHVQTALSIAYVRLAENKAGQVFGSVLEANITNMNK..LERYDHVLKESRELARK..LVEDPD....DIEQ..IKKEILEDRLFKEGLE-ENGK...LDKELRKDITVREKLRSEIYLEVPRILILWDILRWYITSSFDRRNKYVGPFPNIRPSLDTNQLR...AFED...FNPDVVE...I...LKGYMHEKIEYVSNMKNV.........LMK.K.FEIENKMKGLHVKTNPNAAGAALLNTEG.KLPLEAAARVFNT..DPKDVEAEITKFKTFG...KPQ...TKKAKKFLDLIK...............................................................
R9SJH8_9EURY/1-518                   ..................................................................................MDSNRLITKAEEYLKKISEEQIETSRL........SDFEYFKKTY.DNLNNHLNILQEFKETMDTQ.GYTSPYRSLSKY...GISTVADVTAEEASETHRHNQYFRLKASAKKNILDRVKSAIDAHKIALGNLE.EYGLIHCKNCNKTYRI..DNYK-.........................--.AECDCGK.TEYSFSINKNGNHRVDIIPYLPLAGDYMVKMSELTKWGRESFKKVINMLKQERKGSVK..T..VS..L..IIRYR..E.D..KKLIRKRVSLGSDYVNSYEEEIRKRYGKNVRIEALQFHRTKPAIIDDKNTRTALAIGYVKLAELIANRHKDEILKENIKDIDK..LNKYDEIVINAKTANPG..FLDETD....SIEA..WREEKIDADLKDANLKYGNGD...LNRTLEIDLRNRQLLEKSVFINIAPSLILWDIFKYYLTSSNDKRKRQSGPFPYIRSEIDRQQRK...IFQI...TFTKAIE...L...LNKKEHENILPVKEMDLI.........LHK.K.FKLEEELKNSNLKVNYQALGAAMIYNEG.TIPIEECAKSFNL..DVKDVKKESKNIENIA...KPK...NDKSKKFLELIK...............................................................
A0A150J0A1_9EURY/204-326             .........................................................fkkenpqhkrdfydetidmgrspiy---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...-------DKNIRKVL-SIAYAPFGVDAICEDIALFYLKKTYMERKVYGGPFPTIDPEPNEALLG...RFYKtvlLKEEMMN...T...LKDM--------------.........---.-.----------------------------.-------------..----------------...---...------------nlkeknslvaaisyylvsedfdk........................................
E3GYM4_METFV/1-511                   ..................................................................................MNEEGLISRTERLLSEIKKSSIKVDDL........RSYDKAFKIY.RKLKSTLNKLEKIKKTMELK.GYRSPYRSIAKY...-STYIEEPIHEEPHEMARHARYFRIKASIRKNILDRVNSAIASHKIAISNLE.EYIELKCVRCGKRFKI..YE---.........................--.-KCECNReDEYKVVPNEKGIHRIEIIPYLPLSGDYMVKISKLSNWAREAFKKIVRTLRHEKRGTIK..S..TS..L..VIRVF..D.G..KRWLRKKIVINGSFE-ECENKLRKKYGSNLRIEFMQFHRRKARIIDDRYIRNALALGYTCFCENKIEKLKNEIFNSEMKNPEY..FEEYLRIIKDVERSLLS..--LDPE....IREE..IKEEEIKKVLKEKGFLNENEE...LIKEIREDLKIKKEIE-EVFVNVPITLLLWDIANYYLCTSYDRRTKHSGPFPGLRPVLDRHQAK...IFNE...FNKKAVK...I...IKKYFMEKIEYIPNLNEI.........ILE.N.FKIERKMKGLRLKTDPFAFGAAIVNLKS.DIDIEKCSKLFST..TPKNIKREKRNIKIIT...KPS...SDKAKRFLEIVR...............................................................
A6UUW6_META3/124-482                 .............................................................................ddagn---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.--------------KNIIFFLPYGGAYKELLMQLPSIFIKSYKKILNIFELNHKGVLS..S..IT..M..SIVVI..E.N..GKRKFKRIKIEDE---DYDAYIEKHYG-DALITSLKKNYSKNKLITDSYVKKTIVLAYLLTYADDIEKEINKRLNNTLSKHQRdmIVKYLEITSNYDCEYID..-GGVIDf..rRMDEirLKKQELNEELEKCGLF-KDGK...IIDELQTALNIEKNIYDEVCYEIPIKYLSNDLFKYYLYNTPDERSR-SNMFPSILLTPAMSQLTwanMGDN..iNPKSVLDlkfL...LERELPNYKISLKNVGGValylihdwdAVK.K.YGYNKKDIESILK---------------.--DIAPLSDLM--..--SNLKEKNIDIEKIE...KYNtikKKRTKKFLNA--lsk............................................................
A0A1D2W9J9_9EURY/1-522               ..................................................................................MNESVLIARAEKFLDKIKRQRIQVEEL........RDFESFITVY.HYLKENLDELYELRDTMEIK.GYKAPYRSLIRS...SRSSITELKAEEIHDVSRQTQYFRMKAAAKKNILDRVKSSIASHKIVIGHLE.ELATITCSACKKKFKR..HEIEF........................vES.GTCSCGA.KDLILEKNDQGVYRLGTLKYLPLSGEYMVRMSDLSPMGREAFRSIVRVLKHEKRGIVK..T..VS..L..VVKVL..E.D..GRWIRKRVNMDMDDEMNYEREIRKKYGRNARIEFLQFHRKKPAIINDKQVQTALSIAYVKFAKEIVDEIMDNVMDKFLKNRNN..VEIYDNALKAASDVAGS..ITSDIE....DEED..IKNEKLNEILKENNLMDDNDI...INRQLERDLQTRNKIKRKLFVEVPRVFILWDIVRYYLTTSYDRRNKYSGPFPNLRPNLDTNQLK...AFVD...FDKQVVG...I...LKEYTDEKIEYMEDMKEV.........IAK.K.FEIENKIKGLHVKSNPPAVGAAILNITG.KLSIEVASDIFSV..DPENVKAEKEKIETFG...KPT...SKRAQKFLEMIK...............................................................
D7DTU5_METV3/55-170                  ............................................................edentlleynkpnkfknfdkyg---------------------------........-VYSSKTQLL.NDLEKNLNILESYREKMELK.GFDTPYIGVGKL..nG-G-----EEDDIYDILNYSSYLRRVVDEKKGTLERVKYAIVSHKIAIGNLQ.DD--------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------gnld...........................................................
Q8U0L0_PYRFU/3-261                   ...............................................................................tte----ELIARINKILDDIAID---TPGL.......fEDFDV-PKLI.FTFKSRLETLKELEEELERR.--------VGEL...GPT----PIIKDKKSKDPHLSWVYRKRHYRVLTLERLKSAITAHKIALSILE.ANYILKINRSEISLEA..LK-KE.........................NL.SKIKAIE.KDIK-------LGRVEILPYLAYSGDVLRILGQRGIEVREHFKFIKSKLREEGVVRKE..K..FR..I..EVEYL..E.N..GRLKKEKVELPVD--SDIEGELRKRYGRRFRWRVLSYVKTMGVLINNHYTVDNLALAYGT-----------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------lnpre..........................................................
C5A6R7_THEGJ/2-266                   ...............................................................................ttt---EELVAQVNKILDDI---GIDLGEL.......fEEFE-PVKLA.YTLARNVSLLNDLREELERRvGETAP--SL---...--------RFMDKKNRDPHLQWIYRKKHNRALALERLHSAITAHKMALALLS.A--NYTFKLGKRELKA..EELKP.........................EH.------L.PKVRTVPKPIQLGRLEVLPHLAYSGDVLRLLARESIEVREQFKLIKGKLRE--KGIVQ..T..KS..IriEVEYF..E.E..NRLKKTRLDLPAD--ADIEAELRKRFGRRFRWRILSFIKTKGVLINNHYTVDNLALAYASL----------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------dpekgaekl......................................................
A0A1J4UFL3_9ARCH/20-110              .........................................................................eigeagilr---------------------------........----------.---EENVERITRIRSEMLKF.GFDAPFSGVLAA...TAREMGEHGEREAVEQKKQSSYLKYVAKLKKFTLNRIRAAHAAHLMAL----.----------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------rmkdr..........................................................
A0A1Z2TMB0_9EURY/2-266               ...............................................................................ttt---EELVAQVNKILDDI---GIDMDGL........FETFDIPSIS.HRLRENLSLLQELEEDLSRRvGETTP--AVRGM...GKR-----------DRDPHIQWIYKKKRNRVLALERLRAAITAHKMALALIS.AN--YTFFLGKKPVTL..KELT-.........................--.---RENV.EDVEAVPRNVQIGRVEVLPYMAYSGDVLRLLARENIAVRESFKFIKGKLR--EKGTVR..T..RG..L..RIEVEywE.N..NRLKKSRLDLPAD--SDIEGELRKRYGRRFRWRVLSFVKTKGVLINNHYTVDNLSLAYSV-----------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------ldpekgaekl.....................................................
D5VU28_METIM/115-471                 ..............................................................................tddi---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.------------GNKKIVVHLPLDGSYKEKIFTLPTYLIALYKDFLDVLEPKGRGVLT..S..YT..I..SFISF..K.D..GKRSFNRVKVEDP---NYEKYLKERFG-NVIITGIKKNYSKNKLIEDQHVRKCLAISYIYAYKDEIEEEIERRLKNILNEKERriLKEYLELCKDFKDECDV..FGGILDv..rALEEkmLKELNFKKLLEERGLY-KDGE...PIEELRKAIEVKETISKEVGKDIVLRKFSEDIFKFYLYKNPDERSR-SSLFPSIITTPNISYLNw.lKLDI...DGKKVLD...IkfkLEPEFPKYNLSTKYLGGA.........ILYlL.YDWDT-VERYGFKR--------------.-KDVEDLLKKMALvePIKEMLKDKVDIKKLErfgKVK...KKKTKKFLEAL-g..............................................................
A0A100XYU5_9EURY/2-266               ...............................................................................ttt---EELVAQVNKILDDI---GIDMDGL........FETFDIPSIS.FRLKENLSLLQELEDDLSRRvGETTPSAGF---...----------SDKKNKDPHIQWIYKKKRNRVLALERLRSAITAHKMALALISaNYTFLMG---KKLVSL..RELT-.........................--.---RENV.ERIKAVPNPIQLGRVEVLPHLAYSGDVLRLLARESVDVRESFKFIKGKLRE--KGTVRnrG..IR..I..EVEYW..E.N..NRLKKARLDLPTD--ADIEAELRQRYGRRFRWRVLSFVKTRGVLINNHYTVDNLALAYS------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------ildpengarkl....................................................
Q6LYP0_METMP/1-123                   ..................................................................................MDSSVLIKECNDFLDCLSNFGKKLKDFd......sKKEDSVNAVS.ETLENNLKILENFREKMELQ.GFDTPYIGVGRLk.gG-------EDDDIYEIINYSSYLRRMVDEKKGALERVKYAIVSHKIAIGNIQ.E---------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------dmgn...........................................................
D7DTU5_METV3/166-519                 ...............................................................................dgn---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.--------------LDLICNLPYNGSYKESLLQLPHYVVKTYKKFLTILNSEGKSSLS..S..TT..L..AIVVK..E.N..GRRRFKRIKVEEE---DYEKYIRDNYG-DAIITSIKKNYTKSKLLNDQYVKKILALAYLHTYQSLIGDKILENVSKMLKMNELslIAQYKQICQNYERADCE..-GGIIDv..rQINElkFKKLQLVSKLEDCGLY-KEGK...PLKCLEKSLEVENAIFEDACLNVPLSHLSNDLLRYYLNNTADERTR-SNLFPSILVAPSKSQLAw.lRLKN...DYKKVLNyklN...LEKEFPKYDLPIKLTGGIl......lyLAY.D.WDVVESYGYSKPEIE-----SA---LKI.ICNIEEITKKLDC..EPFDIAK----LQEYN...KIK...KKKTKKFLNAL-g..............................................................
A0A150JJH8_9EURY/231-347             ......................................................................hirkvlsiayap---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------FGVDAICEDIALFYLKKTYIERKIYGGPFPTIDPEPNEALLG...KFYKtvlLKEKMMD...T...LREMNLK-----------.........---.-.----------------------------.-------------..----------------...---...------------eknslvaaisyylisedydktllyfsieknefdsaliridn......................
F6BA65_METIK/120-477                 .............................................................................ledig---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.-------------NKKIIQHLPYDGSYKISITGLSPYLINAYKEMLNILQSQGKGVVT..S..IT..L..SLIVF..K.D..GKREFKRIKIEDE---NYEDYIKKHYK-DAIITSMKRNYSKNKLIDDQYVRRVLAVGYLNAYKDDIEKVIRDKLNELLTGEQKkmLETYKKIVGVEEEEDYEggIFDMRV...lDEKK..VRELETIEKLEKEGLY-RNGR...PIEDLKIALDTEKEISKKVATEILTEQLSRDIFMYYLHKSPDERTR-SNLFPSIMTTPSKAHLK...WMKVsgiDVPKVLDlkfL...LEKELPKYNIPLKDLGGL.........VLY.LvYDWDK-VEEFKFKKK--NVE-DLL--KK.IAPIESIKDILKD..KDVD----ISKIEKYS...KVK...KEKTKKFLEAL-g..............................................................
A0A150J0A1_9EURY/1-184               ................................................................................ms-----LISRISSYLDTLKY-SVNPDKL........KDSEYFLNTY.LKIKRDYEELISIRRKIEFL.GYQNPYFVIKGL...K----------DAQ-----DPYFRKRAMEKKICFDNIQHAIAAHRVAIGQLI.D--AMGFEKEGVIYAG..HEALK.........................--.-FTEEGG.-EGKFIFSPDGVYRLEIMKYLSFSGEYMKTLFSLNKVERENYRKIMDMLGDKSK----..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------skps...........................................................
A0A1D2X4J9_9EURY/1-534               .................................................................................m--SELLVTQSEKFLKRIQRKPIIAEGI........EDFDSFIEIY.GYLKNNLYELQNLRNKMEIR.GFTSPYSALKRYgkgNNSNNPEIIPDDVYDQSRHAQYFRIKASNKKNILDQVKSAISSHKIAIGHLE.EYAEITCEKCGQKYKQ..NTIEDilte................ndikkTN.CECTCGC.HEFKFTANKSGICRLELIKYLPLGGEYLLKRSQLTNYSLEAYRKIIKTMRQEKRGRVK..S..IT..V..IAKIK..E.EktGKWISKKVNIDYADESNYELELRKRYGPNVRIELLQFHHKKPSLINDKYVQNALAIAYLQYSENIVNQKIDEIIPQHIQNMEK..INTYNKLTEEARQDACK..LAREAE....ERIE..LEEELKYVKLKKANLMNKNRE...IERELKEDLEKQEDLKKHFYIETSNTLILWDIFKYYLTTSENRRNNYSGPFPNLRPTLDSNQIK...VFNN..iFSKDVVK...L...LQDN-GENIEVIPNMKET.........IQY.K.LELETKRKKLHLKSNHAAYGAIALHKKS.NISLNKAADLLYV..DKEEAAKEKSNLRKIE...KPS...TNKAKKFLEIIN...............................................................
A0A117KQB5_9EURY/2-261               .............................................................................tttee-----LIAQINRVLDDIKTNMNRL--F........ENFDPL-YLA.FNLNRNLAFLRDLEDELSRR.VGET-----LSY...ATSSKKEV--------DPHIRRILLRNHYRMLTLERLRTAITAHKMALATIE.SN--YTFYKGKK---V..IEIKD.........................IT.NKEDLDS.--MKVSEKPIKLGRIEILPYLAYSGDVLRILSQKDTKTRDTFKEIKSKLKEKGQVQRK..G..MR..I..EVEYW..Q.G..GRLKKEKVELPLD--ADVDRELKKRFGQKFRWRLLTYVKTKGVLINSHYTIDNLALAYASL----------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------ypee...........................................................
A0A1D2WKW1_9EURY/1-524               ..................................................................................MPESVLVNKAENYLKAIANDAISLDNI........EDFEYFKDLY.FKLDDRLNFLQELKEDMDAQ.GYTTPFTSLNKY...GSKAVADIDVEEMGENSRHNKIFRMKANAKKNILDRVKSAIDSHKIAIGNLE.QFGYVKCDSCYKKYSM..SEYKQ.........................IE.GKCSCGC.TIFSFKIRKDATHRIEIIPYLPLSGNYMVLRNQLNTFGRESLKQVLNILKQERRGVVK..T..IA..L..VIRFR..DkN..NRLVRKNITLDSEYINNYEEEVRRIYGKRVRIEALRFHRTKPAIIDDKHARTALAIGYVRYSEQIIDDIKDEILKRKLSDFKR..INTYDEIFAEYENKTPN..FIDKYDl..eAIDK..WRKSQIKENFKHLGFYDKYGN...INRSLSRDLKKRENIYKNILRNIASALIIWDIFRYYITTSNNSRKIDISPFPYIRVELDREQRK...VFQT...THKKVIE...T...LNTYTNIKIIPVCEMDLL.........LHD.K.FKFEKQIKNSNIKFNHVALGAALIHENS.DIELEDISNALNI..NESKIKKEIKNIENIK...NPK...SDKSKKFLDLIK...............................................................
A0A1V6N2R0_9EURY/1-546               ..................................................................................MDESILISKAEKYLNEVQNEKISLEKI........SKLESFKSVY.SILTKRLSNLQEMREDMDLK.GYTAPYRSLNKY...GSTSSGDIAFEEMSEVNRHGQYFRMKATAKKNVLDRVKSAIDAHKIAIGHLE.EFGIFKCESCSKSYKP..SAFIElskkksannrnienienkeniskleEK.EECSCGC.NDFKFEINKTGVYRLEIIPYLPLSGNYMVLMSEMTSWGRESFKKVLSILKQERKGVVK..T..VS..A..VIKFK..E.N..DRWIRKRVSLDSEYVNSYEEEIRKEYGKNVRIEFLQFHRTKPTIINDKHARTALAIGYAKYAENIVQNNKESILKDKISNIYK..LAKYDEIVRDVKLQRPK..FVVGED....SLEE..WRRFETENRLKTVGLMSKREN...LDPQLKQDIHKRKNVEKRVFSEVASTLILWDIFKYYLTTSQDRRKRYGGPFPYLRSDIDRKQRR...IFEN...INKEVVN...I...LKNNENEKIIELNNMDLL.........LNK.K.FNLEKKIKGSNIKIDYVSLGAAIISSNC.NIPVSLSSKTFNV..TEKSVENGIKNIDTFK...KPK...SNKSKKFLEMIK...............................................................
A0A150J220_9EURY/1-189               ................................................................................ms-----LISRISSYLDTLKY-SVNPNKL........EDSGYFLSTY.LKLKKDYEELISIRRKIEFL.GYQNPYFVIKGI...--K--------DAQ-----DPYFRKRAMEKKICFDNIQHAIAAHRVAIGQLI.D--AMGFEKEGVIYTG..HEAI-.........................--.KFMEEGG.-EGKFIFSPDGVYRLEILRYLSFSGEYMKTLFSLNKEERENYRKIMDMLGDKSKS---..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------ksstkkri.......................................................
A0A219AMZ2_9EURY/1-518               ..................................................................................MDSNKLITKAENYLNNINKNPIDTNKL........NNFEYFKEVY.YKLNKQLKILQDFKETMDIQ.GYTSPYRSLSKY...GISTVGEVTAEEASETHRHNQYFRMKASNKKNILDRVKSAITSHKIALGNLE.EYGLIRCNNCGKTYRI..EELK-.........................--.DECKCGK.TDYDFYVNLTGNHRIEILPFLPMAGDYMVKISELSKWGRKSFKKVINMLKQERKGSVK..T..VT..L..QIRYK..E.N..KKTIRKKVTLDSEFVDSYEEEVRKRYGKHVRIEKLQFHRTKPAIIDDNNTRTALAIAYVKEGEIIANTYKDELLKEKIKNPDK..LRKYDEIIYNAKTANPK..FLDETD....SVED..WKDDKINEDLIKAKLKYKDGS...LNRTLNIDLKTRERIENSIFINLAPSLILWDIFKYYLTNSQDKRKRQSGPFPHIRSEIDRQQRE...IFRI...TYTQAIK...L...LNKRSNETIIPVKDMDLI.........LHK.K.FNLEYKLKNSNLKIDHYALGAAMIYKEG.KMDINLVAKSFNL..EHEKIKNEAKNIEIIT...KPK...NDKSKKFLELIK...............................................................
A0A150J6J7_9EURY/228-380             ......................................................................ydknirkvlsia---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...-------------------YAPFGVDAICEDIALFYLKKTYMERKIYGGPFPTIDPDPNEALLG...RFYKtviLKEEMMN...T...LR---DMNLKEKNSLVAA.........ISY.-.----------------------------.-------------..----------------...---...------------ylvsedyektllffsldsrelesaliraenygvipkenkyllekivqkgekkditkkfleelk
A0A0U3DQW0_9EURY/1-524               ..................................................................................MEESVLVIKAEKYLKEISNDDINIDDI........DEFENFKNLY.FKLDDRLENLKQLRRDMEVQ.GYGTPFTSLNKY...GTKSIGEVSLEEVSENSRHNQIFRNKANAKKNILDRVKSAIDSHQIALAHLD.QFGYLKCDSCYKKYSV..SEYKQ.........................LN.GKCSCKS.DSFSFKISRQNTYRIEIIPFLPLSGNYRVLMADLSKYGRNSFKKVINALKQERTGHVK..T..IS..P..LFRYK..DkN..NRWLRKRATFDSEFVDNYEEELRKKYGKNVRIEKLEFHRTRPAIIDDKHARTAVALGYVRYAERIISQIRDDILKRRLSDFKR..INIYDEIVHKYNNHTPN..YIDSFDv..aEIEK..WRADKIHEELKNLRYLDRHDE...INRSLKRDLKTRDTIEKTIFENIAPALISWDIFKYYLTTSVSNRKLTTGPFPYIRVELDRQQRK...VFAQ...RFSNVID...I...LNQFSDIKILDVDQKDLI.........LYE.K.FKFEKEMKNSNIKVNHPALGAAHLHLNS.GIDLQSISNTFNV..NESKIKKEIKNIENIK...NPK...TVKSKKFLDLIK...............................................................
A0A166D262_9EURY/1-522               ..................................................................................MDESVLIGDAEKYLKKIGNEPLDLNGI........SDLDIFKSLY.LKLSNRLDVLQSMKENMDAK.GYTAPYRALSRY...GMGNSSDVSFEEVSEVNKYGQYFRMKASAKKNILNRVKSAIDAHKIAIGNLD.EYGLITCNTCSKSYRP..SSLES.........................NGlDKCICGS.SDLYLKLKKHGICRLEILSYLPLSGNYMVLMSKLSRWGRESFKKILKNLKQEKKGSVK..T..VS..L..IIKIR..E.N..NRWISKRVNLDSEYVNSYEEKIREDYG-NVRIKHIQFHRTKPTIINDRNARTALALAYAMYSERLIKEHLDEILSIKLRDYDN..LKKYDNIIYKIGLEKPN..FLSEKD....SLDE..WRKSKIIESLQKEDLMDKNEK...LTIKLAQDKKTRKILEDKVFSNLGLTLILWDIFKYYLTKSNDRRKRHSGPFPYLRGDIDRQQRQ...IFTH...LNKQAIN...I...LKTYACEKIIEINEMDLI.........LYE.K.FKLEKQMKGLNMKINHVALGAALLLNNSnDLDISTLAYAFDL..SEKEIKTESKNLTTVS...KPR...TNKSKQFLKMIK...............................................................
F8AGY3_PYRYC/3-261                   ..............................................................................ttee-----LVARINKILDDIA---IDTPGL........FEDPDVPHIF.FTLRSRLEVLKELEEELERR.VG--DFGPIPVF...----------KDKKSKDPHLSWLYRKRHYRVLTLERLRSAITAHKIALAILE.T---------SYSFRKgrSEVEP.........................ESlKGKDLGK.--IKVVEKSPRLARVDILPYLAYSGDVLKLLGQRGLDVREHFKFIKGKLREEGTLRKE..S..FR..I..EVEYW..E.G..GKLKKERVELPVD--ADIEGELRKRFGKRFRWRVLSYVKTVGVLINNHYTVDNLALAYSS-----------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------ldpsr..........................................................
A0A2H9L0Z6_9ARCH/104-438             ...........................................................................edanlde---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.----------------MKEFLPYGGEYRKMLTKEGEYAADGYKSLLSRFEQK-RYPMK..S..AS..A..LISLM..H.D..GEEVERTVQIDAS--KNAAQTIEKMFGKSAKVKDVQLMRKAAGLIKNYSTKVALFSAACIYASKKAQ---KEALREE-RENKA..LAKYNQILREEGLCADC..TITHAD....----..-RFENVKKRMQKEGFVQKIGAdmiMDAEFEALLHRRRAQKRKDSMQMAAFFVYKILSWYYVCMHEAARKAYS-ALPSVLAEPDEAHLS...IMED...LV-----...-...------PPEYAIAHPAKT.........IWH.K.IKMEENAP----PLSSAAWGPALVCIKE.GVGASFAAKEFNV..PKEEVEGAIGIVKSL-...---...------------iekphgrgakflknlk...............................................
Q6LYP0_METMP/119-474                 .............................................................................edmgn---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.--------------KKILAHLSYDGSYKELLSKIPPFFIKSYKRILSVFETEGKGILS..S..IT..L..SLVIL..E.N..GKRKFKRIKIEEE---DYEGYIKKTFG-DAIITSIKKNYSKNKLLNDQYVKKILSLAYLSACSDEIIEKIDETLKETLSDEERciVKKYRMICSDFKSSDCE..-SGVIDv..rAMEEikLRKMNLKNDLEDRGLY-KNGK...PLKKLKESLEMEDEILENISLEVPLKILSKDLLTYYLKKSADERTR-SNQFPSILVTPSPAHLNw.lAVEN..iAPKKILDlkfL...LEKELPKYEIPIKNLGGVslyllydwnVVE.S.FEFEK-----------------------.-TEIEEILKLMAAinDVKELLKDKIDIKKFE...KYSkikKDKTKNFLNAL-g..............................................................
A0A1D3L1I3_9EURY/1-521               ..................................................................................MNESVLIAKAERFLDNIKHNRIIAEEI........SDFETFRDTY.SYLQDNLEELQDLRDTMEIK.GYKAPYRSIIRY...GGTHSTEMKAEDMYDVGRHTQYFRMRAAAKKNILDRVKSSIASHKIAIGQLE.EYAVLTCSSCGKRFRG..HEIAL.........................LK.KTCECGS.KDFTFSVNEDGVYRLNIIKYLPLSGEYMLRMADLSPMGRDAFRNIVRILKHEKRGIVK..T..LS..L..VVKVL..E.D..GKWVRKRVNIDAKDDMNYEREIRQKYGSNARIEFMQIHRKKPAIINDKQVQTALSIAYVKVAEHNARKIFDEVLKGLISDREK..LDTYDQAFEAAEKRAHR..IAEDAS....DVED..LREEFLNQALKSENLITEDGS...MDKELQKDMETRKCLEKKLFVEMPKILILWDVIRYYLLTSYDRRSKYSGPFPNLRPSLDTNQMK...AFED...FDPFTVD...I...MRSNLKENIRYIPNIKAV.........VSR.K.FEIEGKMKGLHVQMNTPASGAAILHTHG.KLSIEDAADIFSV..KPADVTAEVNKFKTFG...KPQ...TKKARKFLEMVK...............................................................
A0A1J4UFL3_9ARCH/106-434             ............................................................................rmkdre---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.----------------LGEHFPLGGDYLKRLVKGGEHAINSYKTLMDAFSEYG-SYAD..E..VL..A..SVEYF..E.G..GKKKVDSLRISHA--GNLEARVKRVYGNEAKVIGKTVVKGKASIIKNRSTKVALSCAIACFAGKGIAGMLAE------KEEGE..LKQYNEILKKNGITPNS..RLDLAD....GLLK..VKMLVSGAGLGRVGT-DGALE...LNEGLVHEINARRMSGEMLARKKSIQKLAECIFKAYVITNEQQRKS-QSPIPSIAAMPNELQLE...IVDA...-------...-...-----GGGVGGVEKPSEI.........LAK.K.LACEKESHG----MEPHAFGMGFACYEG.KMDVVECMKLFCA..GREEVEGAKL------...---...------------kvggmlsgrgekflrevk.............................................
Y1110_METJA/127-484                  ............................................................................edigni---------------------------........----------.--------------------.------------...----------------------------------------------------.----------------..-----.........................--.-------.---------------NLPPNLPLDGSYKKIMFEFPPYLVTTYKEFLDILEPKGRGILT..S..YT..I..SLIVI..D.K..GKREFKRIKVEDK---NYEKYIKEKFG-NAIITSIKRNFSKNKIIDDQYVRRVLAIGYLNTYKDEIEKAINEKIDKLLNEEEKkyLNRYLELCLLFREEADI..SGGILDvrcmEERK..LKELELKEILEKEGLY-RDGE...PIEPLKKAIKIKNELSKKISKDILIKRFSEDVFKFYLYKTPDERAR-SNLFPSIMITPQRGFLSw.mSVDG..iNCVDVLD...LkfkLEEELPKYQIPLKNIGGV.........ALY.L.IHDWDAVERFNFKKKDI---EDLLKK--.IALIEPIKEILKD..KNVD----VSKLEKFG...KVK...KEKTKKFLDLL-s..............................................................
D5VU28_METIM/1-120                   ..................................................................................MESSTIIKKVNEFLDSIKNINKEIEEA........LKKNKVDNII.KKLRENLEILHEFKAKMEFL.EFDSPYKNIVKI...KAD------SESAQEISNFSSYLRRVANEKKASLERVKHALASHKMAIAHLT.D---------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------dign...........................................................
C6A3G2_THESM/3-265                   tteeliaqinrglddirininrlfenfdprylafnlnrnlmilknmedelsrrvgeahiyvgslgkkerdphirriflrnhy---------------------------........----------.--------------------.------------...-----------------------------RMLTLERLRIAITAHKIALATID.SHYTF--YKGKKGVDI..KNIT-.........................--.NKRDLEK.--LKVAEKSIKLGRLEVLPHLAYSGDVLKILSQQDNKVRDTFKEIKSKLKEKGQIRKK..G..IR..I..EVEYW..Q.E..GRLKKERLDFPVE--ADIDSELRKRFGQKYRWRVLSYVKTKGVLITSHYTVDNIALAYAST----------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------ypkkgvk........................................................
A0A150J6J7_9EURY/1-187               ................................................................................ms-----LISKISNYLDSLN-YRIDPEKL........KDSKYFLDSY.LKLKIDYEELISIRRKIEFL.GYQNPYFVIKGI...--K--------DAQ-----DPYFRKRAMEKKICFDNVQHAIAAHRVAIGQLI.DA--MAFENNDVIYAG..HEAIK.........................-F.--IENGG.-GGKFIFNPDGVYRLEILRYLSFSGEYMKTLFSLTKLERENYRKIMDMLGDKSK----..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------skpsikk........................................................
F6BA65_METIK/1-126                   ..................................................................................MESSELIRESNEFLDNLKRLKFEIEELl.....kkKLEDSVIEEYaKKLEENLKILEELKEKMELL.GFDTPYTNVGKL...-----KGFDSDELYEIMNYTSYLRRIANEKKGVLERIRHSVVSHKIALGHLL.E---------------..-----.........................--.-------.----------------------------------------------------------..-..--..-..-----..-.-..-----------------------------------------------------------------------------------..-----------------..------....----..---------------------...----------------------------------------------------------------...----...-------...-...------------------.........---.-.----------------------------.-------------..----------------...---...------------dignk..........................................................
#=GC seq_cons                        .......................................................................................LlspspphLcplt...lphttl.........p.t.h.plh..hLpppLp.Lpphccph-hp.GhpsP..sl.th...t.........p-h.p.p.a.pahhh+tpt+t.hL-Rl+sAIsuHKhAlu.Lp.t...h....t...hp...pph.................................p.t....hph..p..thhRl-ll.aLshSGshhhhhuphs.hsR-ua+plhshLcpct+Ghlc..s..hp..l...lchh..-.s..s+hhpp+lpls.c...shEtclRcpaG.phRhchlphh+p+sslIss+ashssLuluYs.h............................................................................................................................................................................................................................................................................................................................................................
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