GenomeNet

Database: Pfam
Entry: DUF608
LinkDB: DUF608
Original site: DUF608 
#=GF ID   DUF608
#=GF AC   PF04685.13
#=GF DE   Glycosyl-hydrolase family 116, catalytic region
#=GF AU   Mifsud W;0000-0002-9805-6461
#=GF SE   Pfam-B_5657 (release 7.5)
#=GF GA   26.30 26.30;
#=GF TC   26.30 26.30;
#=GF NC   26.20 26.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   17105727
#=GF RT   Identification of the non-lysosomal glucosylceramidase as
#=GF RT   beta-glucosidase 2.
#=GF RA   Boot RG, Verhoek M, Donker-Koopman W, Strijland A, van Marle J,
#=GF RA   Overkleeft HS, Wennekes T, Aerts JM;
#=GF RL   J Biol Chem. 2007;282:1305-1312.
#=GF RN   [2]
#=GF RM   20427274
#=GF RT   A new archaeal beta-glycosidase from Sulfolobus solfataricus:
#=GF RT   seeding a novel retaining beta-glycan-specific glycoside
#=GF RT   hydrolase family along with the human non-lysosomal
#=GF RT   glucosylceramidase GBA2.
#=GF RA   Cobucci-Ponzano B, Aurilia V, Riccio G, Henrissat B, Coutinho
#=GF RA   PM, Strazzulli A, Padula A, Corsaro MM, Pieretti G, Pocsfalvi G,
#=GF RA   Fiume I, Cannio R, Rossi M, Moracci M;
#=GF RL   J Biol Chem. 2010;285:20691-20703.
#=GF RN   [3]
#=GF RM   23332917
#=GF RT   Mutations in GBA2 cause autosomal-recessive cerebellar ataxia
#=GF RT   with spasticity.
#=GF RA   Hammer MB, Eleuch-Fayache G, Schottlaender LV, Nehdi H, Gibbs
#=GF RA   JR, Arepalli SK, Chong SB, Hernandez DG, Sailer A, Liu G, Mistry
#=GF RA   PK, Cai H, Shrader G, Sassi C, Bouhlal Y, Houlden H, Hentati F,
#=GF RA   Amouri R, Singleton AB;
#=GF RL   Am J Hum Genet. 2013;92:245-251.
#=GF DR   INTERPRO; IPR006775;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This represents a family of archaeal, bacterial and eukaryotic
#=GF CC   glycosyl hydrolases, that belong to superfamily GH116. The
#=GF CC   primary catabolic pathway for glucosylceramide is catalysis by
#=GF CC   the lysosomal enzyme glucocerebrosidase. In higher eukaryotes,
#=GF CC   glucosylceramide is the precursor of glycosphingolipids, a
#=GF CC   complex group of ubiquitous membrane lipids [1]. Mutations in
#=GF CC   the human protein cause motor-neurone defects in hereditary
#=GF CC   spastic paraplegia [3]. The catalytic nucleophile, identified in
#=GF CC   UniProtKB:Q97YG8_SULSO, is a glutamine-335, with the likely
#=GF CC   acid/base at Asp-442 and the aspartates at Asp-406 and Asp-458
#=GF CC   residues also playing a role in the catalysis of glucosides and
#=GF CC   xylosides that are beta-bound to hydrophobic groups. The family
#=GF CC   is defined as GH116, which presently includes enzymes with
#=GF CC   beta-glucosidase, EC:3.2.1.21, beta-xylosidase, EC:3.2.1.37, and
#=GF CC   glucocerebrosidase EC:3.2.1.45 activity [1,2].
#=GF SQ   1578
#=GS A0A1Q3SPS4_9CHLR/455-760    AC A0A1Q3SPS4.1
#=GS H2YFK8_CIOSA/531-805        AC H2YFK8.1
#=GS A0A0F0LCP0_9MICO/503-777    AC A0A0F0LCP0.1
#=GS A0A1J6JA08_NICAT/532-892    AC A0A1J6JA08.1
#=GS A0A0E0Q7K2_ORYRU/489-807    AC A0A0E0Q7K2.1
#=GS A0A287FHC8_HORVV/509-870    AC A0A287FHC8.1
#=GS A0A075AB10_9TREM/601-985    AC A0A075AB10.1
#=GS A0A287FH95_HORVV/178-539    AC A0A287FH95.1
#=GS H2YFL0_CIOSA/466-850        AC H2YFL0.1
#=GS A0A2I2YRQ7_GORGO/521-859    AC A0A2I2YRQ7.1
#=GS A0A1U8KA58_GOSHI/551-912    AC A0A1U8KA58.1
#=GS Q8YTA7_NOSS1/421-799        AC Q8YTA7.1
#=GS A0A1M6VDW1_9BACT/545-986    AC A0A1M6VDW1.1
#=GS A0A094KME4_ANTCR/410-775    AC A0A094KME4.1
#=GS A0A287FHC0_HORVV/52-413     AC A0A287FHC0.1
#=GS Q7XDG7_ORYSJ/557-918        AC Q7XDG7.2
#=GS A0A0F8AIP1_LARCR/578-778    AC A0A0F8AIP1.1
#=GS A0A2I4CLV0_9TELE/471-836    AC A0A2I4CLV0.1
#=GS A0A1M5D7M7_9BACE/508-705    AC A0A1M5D7M7.1
#=GS A0A182TZD0_9DIPT/367-787    AC A0A182TZD0.1
#=GS A0A0V0VDX4_9BILA/450-813    AC A0A0V0VDX4.1
#=GS A0A091TLW9_PHALP/411-661    AC A0A091TLW9.1
#=GS A0A068Y779_ECHMU/610-986    AC A0A068Y779.1
#=GS A0A1Q3BE79_CEPFO/560-921    AC A0A1Q3BE79.1
#=GS A0A1D6PRH5_MAIZE/398-758    AC A0A1D6PRH5.1
#=GS A0A1N7JN29_9RHOB/390-754    AC A0A1N7JN29.1
#=GS F4KYV6_HALH1/472-770        AC F4KYV6.1
#=GS A0A0D3GVN9_9ORYZ/529-869    AC A0A0D3GVN9.1
#=GS A0A1S3Y3D1_TOBAC/449-809    AC A0A1S3Y3D1.1
#=GS A0A1U7ZDU5_NELNU/527-887    AC A0A1U7ZDU5.1
#=GS A0A1Q3Z4M7_9RHIZ/466-776    AC A0A1Q3Z4M7.1
#=GS A0A0Q7DMQ3_9RHIZ/465-775    AC A0A0Q7DMQ3.1
#=GS A0A1V4JTG6_PATFA/428-793    AC A0A1V4JTG6.1
#=GS A0A2I4EEP9_9ROSI/380-740    AC A0A2I4EEP9.1
#=GS A0A0G8B1M5_9SYNE/436-808    AC A0A0G8B1M5.1
#=GS A0A0F0KZI6_9MICO/487-761    AC A0A0F0KZI6.1
#=GS A0A0E0HZU5_ORYNI/489-807    AC A0A0E0HZU5.1
#=GS M5T9S5_9PLAN/519-813        AC M5T9S5.1
#=GS A0A257AJT6_9ARCH/447-648    AC A0A257AJT6.1
#=GS A8X7A9_CAEBR/470-836        AC A8X7A9.1
#=GS W5MSZ8_LEPOC/470-835        AC W5MSZ8.1
#=GS T1FB65_HELRO/379-422        AC T1FB65.1
#=GS A0A0E0LQJ0_ORYPU/488-848    AC A0A0E0LQJ0.1
#=GS A0A1H4BK76_9BACT/488-777    AC A0A1H4BK76.1
#=GS A0A091S9V1_NESNO/413-778    AC A0A091S9V1.1
#=GS R9MRL3_9FIRM/461-769        AC R9MRL3.1
#=GS A0A1S3CMC1_CUCME/532-892    AC A0A1S3CMC1.1
#=GS M5TW08_9PLAN/497-819        AC M5TW08.1
#=GS A0A0E0R689_ORYRU/413-773    AC A0A0E0R689.1
#=GS A0A0V1DDK4_TRIBR/1349-1712  AC A0A0V1DDK4.1
#=GS J9P6J8_CANLF/677-1042       AC J9P6J8.1
#=GS A0A1M6VIX8_9BACT/811-958    AC A0A1M6VIX8.1
#=GS D8RWH2_SELML/488-845        AC D8RWH2.1
#=GS A0A093QRF7_PYGAD/415-780    AC A0A093QRF7.1
#=GS A0A016UZ50_9BILA/297-551    AC A0A016UZ50.1
#=GS A0A1S3CBS6_CUCME/412-772    AC A0A1S3CBS6.1
#=GS A0A1I5TG55_9BACT/644-922    AC A0A1I5TG55.1
#=GS A0A093Q5D1_9PASS/412-777    AC A0A093Q5D1.1
#=GS A0A1E5QGY6_9CYAN/424-813    AC A0A1E5QGY6.1
#=GS L8MAD3_9CYAN/422-800        AC L8MAD3.1
#=GS A0A143PGE0_9BACT/524-819    AC A0A143PGE0.1
#=GS A0A0E0F434_9ORYZ/327-682    AC A0A0E0F434.1
#=GS A0A146GGN5_9BACT/426-737    AC A0A146GGN5.1
#=GS A0A1M5BYY8_9CLOT/455-755    AC A0A1M5BYY8.1
#=GS V4M593_EUTSA/535-896        AC V4M593.1
#=GS A0A0E0Q7K3_ORYRU/489-850    AC A0A0E0Q7K3.1
#=GS G5BKZ6_HETGA/516-881        AC G5BKZ6.1
#=GS A0A1S3Y396_TOBAC/528-888    AC A0A1S3Y396.1
#=GS A3IPZ1_9CYAN/418-796        AC A3IPZ1.1
#=GS A0A287WYP7_HORVV/63-423     AC A0A287WYP7.1
#=GS A0A1I3TZH5_9BACL/453-762    AC A0A1I3TZH5.1
#=GS A0A0D7W6U1_9FLAO/392-543    AC A0A0D7W6U1.1
#=GS A0A0D2T0C9_GOSRA/722-850    AC A0A0D2T0C9.1
#=GS F1A2R6_DICPU/808-1170       AC F1A2R6.1
#=GS F4B5C4_ACIHW/332-656        AC F4B5C4.1
#=GS A0A1C2GKJ0_9SPHI/419-561    AC A0A1C2GKJ0.1
#=GS A0A0E0EYT5_9ORYZ/539-897    AC A0A0E0EYT5.1
#=GS A0A2G9RDU8_LITCT/258-412    AC A0A2G9RDU8.1
#=GS A0A1G0XCP0_9BACT/643-807    AC A0A1G0XCP0.1
#=GS I1I0F1_BRADI/509-874        AC I1I0F1.1
#=GS A0A0D9XKI8_9ORYZ/485-843    AC A0A0D9XKI8.1
#=GS A0A2A2KV75_9BILA/491-566    AC A0A2A2KV75.1
#=GS A0A287WYM2_HORVV/456-818    AC A0A287WYM2.1
#=GS A0A0E0M8M9_ORYPU/537-895    AC A0A0E0M8M9.1
#=GS A0A1U7VEG3_NICSY/528-888    AC A0A1U7VEG3.1
#=GS K7VX08_9NOST/414-790        AC K7VX08.1
#=GS A0A2C9JSR0_BIOGL/459-814    AC A0A2C9JSR0.1
#=GS A0A1M5C7G4_9THEO/448-761    AC A0A1M5C7G4.1
#=GS M0ZKD5_SOLTU/37-397         AC M0ZKD5.1
#=GS A0A0D2S0N4_GOSRA/498-859    AC A0A0D2S0N4.1
#=GS A0A0B2S4J8_GLYSO/800-893    AC A0A0B2S4J8.1
#=GS A0A287FHC2_HORVV/275-636    AC A0A287FHC2.1
#=GS A0A158QN58_HAEPC/323-691    AC A0A158QN58.1
#=GS W6RMY1_9RHIZ/279-444        AC W6RMY1.1
#=GS U9VHJ1_9CYAN/418-820        AC U9VHJ1.1
#=GS A0A164Z408_9SYNE/228-600    AC A0A164Z408.1
#=GS A0A061FKA9_THECC/524-859    AC A0A061FKA9.1
#=GS A0A1S3Y2W5_TOBAC/524-884    AC A0A1S3Y2W5.1
#=GS U5D9G1_AMBTC/567-928        AC U5D9G1.1
#=GS I1LCH2_SOYBN/534-895        AC I1LCH2.2
#=GS A0A2K5LU49_CERAT/521-886    AC A0A2K5LU49.1
#=GS K9PG07_9CYAN/416-792        AC K9PG07.1
#=GS K9Q3I4_9CYAN/418-802        AC K9Q3I4.1
#=GS A0A0E0EYT8_9ORYZ/557-794    AC A0A0E0EYT8.1
#=GS A0A0D2T0C9_GOSRA/531-724    AC A0A0D2T0C9.1
#=GS A0A1D5RQI5_WHEAT/504-865    AC A0A1D5RQI5.1
#=GS B5IN55_9CYAN/444-818        AC B5IN55.1
#=GS A0A0C2GZY7_9BILA/214-356    AC A0A0C2GZY7.1
#=GS H0YUD6_TAEGU/415-780        AC H0YUD6.1
#=GS A0A1J6JX78_NICAT/528-889    AC A0A1J6JX78.1
#=GS S8E2K0_9LAMI/507-867        AC S8E2K0.1
#=GS A0A2K1WQZ9_POPTR/527-758    AC A0A2K1WQZ9.1
#=GS W4VAH4_9FIRM/6-158          AC W4VAH4.1
#=GS A0A287FHA1_HORVV/458-819    AC A0A287FHA1.1
#=GS A0A0W8JD36_9VIBR/509-939    AC A0A0W8JD36.1
#=GS F7H1I4_CALJA/477-842        AC F7H1I4.1
#=GS A0A016UXY4_9BILA/324-578    AC A0A016UXY4.1
#=GS L8LW99_9CHRO/418-796        AC L8LW99.1
#=GS A0A1I7UT08_9PELO/458-824    AC A0A1I7UT08.1
#=GS A0A1G0SQ69_9BACT/342-521    AC A0A1G0SQ69.1
#=GS A0A286RGG5_9PLAN/710-997    AC A0A286RGG5.1
#=GS A0A1D6PRG5_MAIZE/446-777    AC A0A1D6PRG5.1
#=GS D3ER19_ATETH/418-796        AC D3ER19.1
#=GS A0A231R621_9BACL/382-757    AC A0A231R621.1
#=GS A0A1A9W0D7_9MUSC/513-944    AC A0A1A9W0D7.1
#=GS A0A261C0L2_9PELO/491-857    AC A0A261C0L2.1
#=GS A0A1U8LKY8_GOSHI/530-890    AC A0A1U8LKY8.1
#=GS A0A1U7VEJ7_NICSY/516-876    AC A0A1U7VEJ7.1
#=GS A0A0N4X7D7_HAEPC/28-171     AC A0A0N4X7D7.1
#=GS A0A2K1R4Q0_POPTR/71-428     AC A0A2K1R4Q0.1
#=GS A0A1Y0RRM8_9CYAN/441-818    AC A0A1Y0RRM8.1
#=GS A0A0E0F430_9ORYZ/413-496    AC A0A0E0F430.1
#=GS B7VTD0_VIBTL/553-986        AC B7VTD0.1
#=GS A0A1J6J3X1_NICAT/523-883    AC A0A1J6J3X1.1
#=GS A0A0B0QT92_APHFL/418-794    AC A0A0B0QT92.1
#=GS A8LAN5_FRASN/563-921        AC A8LAN5.1
#=GS A0A1D6SF05_WHEAT/465-825    AC A0A1D6SF05.1
#=GS A0A1R1CL97_9BACL/466-743    AC A0A1R1CL97.1
#=GS A0A183QX38_9TREM/1-216      AC A0A183QX38.1
#=GS A3YV91_9SYNE/439-813        AC A3YV91.1
#=GS A0A1F5A212_9BACT/504-908    AC A0A1F5A212.1
#=GS W5JIF6_ANODA/383-820        AC W5JIF6.1
#=GS K0IFG5_NITGG/141-298        AC K0IFG5.1
#=GS C3YQ20_BRAFL/520-564        AC C3YQ20.1
#=GS A0A2I0LI71_COLLI/431-796    AC A0A2I0LI71.1
#=GS A0A1U8MLX6_GOSHI/506-866    AC A0A1U8MLX6.1
#=GS U5GJP1_POPTR/555-916        AC U5GJP1.1
#=GS G0NCM7_CAEBE/474-840        AC G0NCM7.1
#=GS A0A2A2LUY0_9BILA/289-516    AC A0A2A2LUY0.1
#=GS G3WMQ4_SARHA/491-857        AC G3WMQ4.1
#=GS A0A1B6PR30_SORBI/490-850    AC A0A1B6PR30.1
#=GS A0A1F8S6F6_9CHLR/368-731    AC A0A1F8S6F6.1
#=GS A0A1S4C8G5_TOBAC/532-892    AC A0A1S4C8G5.1
#=GS A0A2H2IXP6_CAEJA/11-353     AC A0A2H2IXP6.1
#=GS B3RSC0_TRIAD/461-826        AC B3RSC0.1
#=GS A0A0D9XQQ1_9ORYZ/492-844    AC A0A0D9XQQ1.1
#=GS A0A1D5XR60_WHEAT/531-892    AC A0A1D5XR60.1
#=GS R0GUW5_9BRAS/525-885        AC R0GUW5.1
#=GS A0A258WM14_9SPHI/486-771    AC A0A258WM14.1
#=GS A0A1B6QKA4_SORBI/557-918    AC A0A1B6QKA4.1
#=GS F1MND2_BOVIN/519-884        AC F1MND2.2
#=GS A0A2I4EEN9_9ROSI/525-885    AC A0A2I4EEN9.1
#=GS F6U9S8_CIOIN/419-781        AC F6U9S8.2
#=GS A0A0K0E7Z3_STRER/572-938    AC A0A0K0E7Z3.1
#=GS A0A0E0HZU8_ORYNI/497-858    AC A0A0E0HZU8.1
#=GS V4T5D4_9ROSI/502-862        AC V4T5D4.1
#=GS A0A1F4MRV5_9BACT/355-531    AC A0A1F4MRV5.1
#=GS A0A0V1DDT3_TRIBR/1301-1664  AC A0A0V1DDT3.1
#=GS A0A1E5WEH9_9POAL/571-932    AC A0A1E5WEH9.1
#=GS A0A1U8KEI8_GOSHI/454-815    AC A0A1U8KEI8.1
#=GS F4A018_MAHA5/458-769        AC F4A018.1
#=GS G3TE96_LOXAF/513-878        AC G3TE96.1
#=GS A9B7I0_HERA2/403-763        AC A9B7I0.1
#=GS A0A0R2U1S1_9CYAN/437-708    AC A0A0R2U1S1.1
#=GS A0A1N6WPT0_9ACTN/801-1108   AC A0A1N6WPT0.1
#=GS A0A0D6AMD0_9CHRO/417-795    AC A0A0D6AMD0.1
#=GS A0A2H3Z1H8_PHODC/520-879    AC A0A2H3Z1H8.1
#=GS D8QZD7_SELML/488-845        AC D8QZD7.1
#=GS A0A0D3D5E8_BRAOL/531-892    AC A0A0D3D5E8.1
#=GS A0A0E0F433_9ORYZ/394-749    AC A0A0E0F433.1
#=GS A0A1G6UG14_9MICO/479-755    AC A0A1G6UG14.1
#=GS A0A287FHB8_HORVV/236-597    AC A0A287FHB8.1
#=GS A0A016W1E8_9BILA/192-257    AC A0A016W1E8.1
#=GS A0A183FMW1_HELBK/107-211    AC A0A183FMW1.1
#=GS A0A1B1Y3L6_9FLAO/446-777    AC A0A1B1Y3L6.1
#=GS F7H1J0_CALJA/468-833        AC F7H1J0.1
#=GS W9RAU8_9ROSA/257-617        AC W9RAU8.1
#=GS K3ZQH4_SETIT/511-872        AC K3ZQH4.1
#=GS R7ENS9_9BACE/404-778        AC R7ENS9.1
#=GS A0A172TJH0_9BACL/480-776    AC A0A172TJH0.1
#=GS A0A059ATG1_EUCGR/528-888    AC A0A059ATG1.1
#=GS A0A2B4S1T6_STYPI/901-1183   AC A0A2B4S1T6.1
#=GS A0A1Z4G148_9CYAN/424-800    AC A0A1Z4G148.1
#=GS A0A287FHD1_HORVV/509-870    AC A0A287FHD1.1
#=GS A0A0R0EM68_SOYBN/535-896    AC A0A0R0EM68.1
#=GS A0A1B1Y3E1_9FLAO/423-808    AC A0A1B1Y3E1.1
#=GS G0MUE5_CAEBE/446-810        AC G0MUE5.1
#=GS A0A0G1L4W0_9BACT/449-730    AC A0A0G1L4W0.1
#=GS A0A183I3R2_9BILA/1-51       AC A0A183I3R2.1
#=GS C9RN35_FIBSS/520-956        AC C9RN35.1
#=GS A0A1G0ZNX1_9BACT/459-759    AC A0A1G0ZNX1.1
#=GS A0A0D0LDS6_9FLAO/402-558    AC A0A0D0LDS6.1
#=GS A0A1H7Z1D7_9BACL/448-726    AC A0A1H7Z1D7.1
#=GS A0A1Q4F3H2_9SPHI/487-776    AC A0A1Q4F3H2.1
#=GS A0A0S8JJF1_9BACT/444-753    AC A0A0S8JJF1.1
#=GS A0A1B0BK61_9MUSC/11-86      AC A0A1B0BK61.1
#=GS A0A2H3ZST5_PHODC/610-863    AC A0A2H3ZST5.1
#=GS B0JQK4_MICAN/416-775        AC B0JQK4.1
#=GS K9U6E1_9CYAN/423-805        AC K9U6E1.1
#=GS A0A1U7YQF7_NELNU/563-797    AC A0A1U7YQF7.1
#=GS A0A0D9WYB5_9ORYZ/463-824    AC A0A0D9WYB5.1
#=GS A0A0V1MD17_9BILA/1309-1672  AC A0A0V1MD17.1
#=GS K9TB22_9CYAN/422-809        AC K9TB22.1
#=GS R0FI98_9BRAS/492-852        AC R0FI98.1
#=GS A0A1G7M0P8_9SPHI/415-703    AC A0A1G7M0P8.1
#=GS A0A0N4V4N8_ENTVE/454-831    AC A0A0N4V4N8.1
#=GS A0A2B4S094_STYPI/340-630    AC A0A2B4S094.1
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A0A1Y5KFV7_9BACL/450-742               ......................................................................................ksdyhaav--------...--...-.-..--..-..-..-.--..-.......--..-..----...---------------........................--.------.-.--..-----....................---.-...........-----...--...---.----.--...-.-..........................-----.-.--.-......-....-....-....-.----....-.....D...G...QMGAIV.RTYREWRLS....GD............................................................................................................TT..WLR.KL.W.PA.V.KK.ALafawasD..................N....E......H.....G.....WD....R....N....RDG.......I.....L............E............G.....A...-....-...Q....H.....H.T...L....DV..........E.-.....L.....Y.....G.......P.......N..S..Y......L..NGY...Y.QA.A...LLAAARMG....................R..AL...............................G..DGD.-..AD.Q..................YETMYR.QG.....KSWI.....DANAF.........................N...G..E......Y..Yhqlldlsdpa........................................................................................ypvdpelgeiK..Y....Q-.---....IGQGCH.IDQ...VIGQWHA.RV...A.G.LGD...........................IFER.SQVRSALASIYR.YNFA..Smreha.....................nsnrvyA.....LND.E......R..GV.L.VCTW...PR...............................gG..Q..PL......V......PVPY.AD........E.C.MTG..FEYQAASH.MI.Y..........................E.G.......L.......V.......DEGLSVVRAVRER----.....YDGVRRNP.....----..-.W..............N.....EF.ECG.sHYARAMSSYAL............................................................................................................................................................
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A0A287FHD9_HORVV/52-413                ..............................................................................................GKFLYLEG...VE...Y.F..MW..C..T..Y.DV..H.......FY..A..SFAL...LDLFPKIELSIQRDF........................AR.AVLRED.R.TR..VKFLA....................DGT.W...........GTRKV...IG...AVP.HDLG.--...A.H..........................DPWHE.L.NA.Y......N....I....H....D.TSRW....K.....D...L...NPKFVL.QVYRDFTAT....DD............................................................................................................MS..FGK.DV.W.PA.V.CT.AM......E..................Y....I......E.....Q.....FD....R....D....GDS.......M.....I............E............N.....D...G....F...P....D.....Q.T...Y....DT..........W.T.....V.....L.....G.......V.......S..A..Y......C..GCL...W.LA.A...LQAAAAMA....................R..SL...............................G..HDD.Y..AD.R..................CMVKFA.KA.....KHVF.....EAKLW.........................N...G..S......Y..F............................................................................................................N..Y....DS.GTS...ySSRSIQ.ADQ...LAGQWYT.AS...S.G.LPP...........................LFDE.DRIKCTLQKIFD.YNVM..R................................V.....KGG.R......I..GA.V.NGMH...PN................................G..K..VD......E......TCMQ.SR........E.I.WTG..VTYGLAAT.ML.L..........................H.G.......M.......E.......DQAFTTAQGIFLAGWSEe...gYGYWFQTP.....EGWT..I.D..............G.....HY.RSL..IYMRPLAIWAM............................................................................................................................................................
A0A1I7X7X7_HETBA/13-57                 ..............................................................................................GRFGYMES...WE...Y.Y..ML..N..T..Y.DV..H.......FY..A..SWAL...LENWPQLEMSIQLNF........................--.------.-.--..-----....................---.-...........-----...--...---.----.--...-.-..........................-----.-.--.-......-....-....-....-.----....-.....-...-...------.---------....--............................................................................................................--..---.--.-.--.-.--.--......-..................-....-......-.....-.....--....-....-....---.......-.....-............-............-.....-...-....-...-....-.....-.-...-....--..........-.-.....-.....-.....-.......-.......-..-..-......-..---...-.--.-...--------....................-..--...............................-..---.-..--.-..................------.--.....----.....-----.........................-...-..-......-..-............................................................................................................-..-....--.---....------.---...-------.--...-.-.---...........................----.------------.----..-................................-.....---.-......-..--.-.----...--................................-..-..--......-......----.--........-.-.---..--------.--.-..........................-.-.......-.......-.......-----------------.....--------.....----..-.-..............-.....--.---..-----------fge.........................................................................................................................................................
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