#=GF ID   DX
#=GF AC   PF01666.21
#=GF DE   DX module
#=GF AU   Hutter H;
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   [1]
#=GF GA   25.00 25.00;
#=GF TC   25.20 25.20;
#=GF NC   24.90 24.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR002593;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This domain has no known function. It is found in several C.
#=GF CC   elegans proteins. The domain contains 6 conserved cysteines that
#=GF CC   probably form three disulphide bridges.
#=GF SQ   60
#=GS G0NTD7_CAEBE/166-240      AC G0NTD7.1
#=GS E3LNW1_CAERE/165-243      AC E3LNW1.1
#=GS A0A2G5UNF3_9PELO/159-231  AC A0A2G5UNF3.1
#=GS G0MUN8_CAEBE/429-512      AC G0MUN8.1
#=GS A0A2G5SGY1_9PELO/549-626  AC A0A2G5SGY1.1
#=GS A0A2G5V6V7_9PELO/589-641  AC A0A2G5V6V7.1
#=GS A0A2G5VKS6_9PELO/460-537  AC A0A2G5VKS6.1
#=GS E3MVT0_CAERE/506-583      AC E3MVT0.1
#=GS A0A261BNH1_9PELO/202-280  AC A0A261BNH1.1
#=GS Q21247_CAEEL/270-359      AC Q21247.3
#=GS G0NZ63_CAEBE/490-567      AC G0NZ63.1
#=GS A0A261BXA4_9PELO/192-266  AC A0A261BXA4.1
#=GS A0A2G5SH50_9PELO/549-626  AC A0A2G5SH50.1
#=GS G0NDI2_CAEBE/644-721      AC G0NDI2.1
#=GS A0A8R1DQ48_CAEJA/646-723  AC A0A8R1DQ48.1
#=GS G0MLF6_CAEBE/78-153       AC G0MLF6.1
#=GS Q20917_CAEEL/300-378      AC Q20917.1
#=GS G0NSK1_CAEBE/144-215      AC G0NSK1.1
#=GS A0A261APN4_9PELO/157-231  AC A0A261APN4.1
#=GS A8XGB2_CAEBR/401-478      AC A8XGB2.2
#=GS G0NAR9_CAEBE/116-186      AC G0NAR9.1
#=GS G0MS20_CAEBE/209-287      AC G0MS20.1
#=GS A0A2G5VKQ2_9PELO/457-534  AC A0A2G5VKQ2.1
#=GS A8XUA2_CAEBR/56-95        AC A8XUA2.2
#=GS A0A2G5U630_9PELO/171-245  AC A0A2G5U630.1
#=GS O01600_CAEEL/467-543      AC O01600.2
#=GS A0A8R1HIX7_CAEJA/222-300  AC A0A8R1HIX7.1
#=GS A0A2G5V734_9PELO/588-640  AC A0A2G5V734.1
#=GS A0A8R1HU98_CAEJA/111-200  AC A0A8R1HU98.1
#=GS E3M6C4_CAERE/169-243      AC E3M6C4.1
#=GS A0A2G5U6M3_9PELO/178-252  AC A0A2G5U6M3.1
#=GS A0A261BG55_9PELO/445-522  AC A0A261BG55.1
#=GS A0A2G5U626_9PELO/161-235  AC A0A2G5U626.1
#=GS G0MXQ1_CAEBE/167-241      AC G0MXQ1.1
#=GS A0A8R1E0N8_CAEJA/166-238  AC A0A8R1E0N8.1
#=GS H2L2B6_CAEEL/163-196      AC H2L2B6.1
#=GS A0A8R1DR07_CAEJA/634-711  AC A0A8R1DR07.1
#=GS A0A2G5TJX7_9PELO/148-222  AC A0A2G5TJX7.1
#=GS A0A8R1I946_CAEJA/67-141   AC A0A8R1I946.1
#=GS A0A8R1IGJ3_CAEJA/131-205  AC A0A8R1IGJ3.1
#=GS A0A2G5TJX3_9PELO/152-226  AC A0A2G5TJX3.1
#=GS E3LN37_CAERE/526-603      AC E3LN37.1
#=GS E3LUN1_CAERE/180-254      AC E3LUN1.1
#=GS A0A8R1HI25_CAEJA/176-254  AC A0A8R1HI25.1
#=GS E3LRG6_CAERE/563-638      AC E3LRG6.1
#=GS G0N4K2_CAEBE/880-936      AC G0N4K2.1
#=GS H2L2B7_CAEEL/163-237      AC H2L2B7.1
#=GS E3NNZ2_CAERE/154-228      AC E3NNZ2.1
#=GS A8XMS2_CAEBR/94-166       AC A8XMS2.1
#=GS A8X701_CAEBR/321-399      AC A8X701.2
#=GS A0A8R1HGX5_CAEJA/132-210  AC A0A8R1HGX5.1
#=GS A0A2G5TFD1_9PELO/328-406  AC A0A2G5TFD1.1
#=GS A0A8R1HU98_CAEJA/71-109   AC A0A8R1HU98.1
#=GS A0A8R1HTE7_CAEJA/73-162   AC A0A8R1HTE7.1
#=GS A8XGB0_CAEBR/445-522      AC A8XGB0.2
#=GS A0A8R1HTE7_CAEJA/33-71    AC A0A8R1HTE7.1
#=GS A0A261C0X5_9PELO/551-624  AC A0A261C0X5.1
#=GS A0A8R1IJD4_CAEJA/137-211  AC A0A8R1IJD4.1
#=GS G0NWL1_CAEBE/490-567      AC G0NWL1.1
#=GS A8WQR1_CAEBR/147-221      AC A8WQR1.2
G0NTD7_CAEBE/166-240                 ........FRTNIDCDVGDKIASKYE.FMFCHNETGNLWVM.G.KLNMNGDEVIK-HWT.....LCHLNKDCLE....GQ..VCVK..........EDICRYRCYDDP..................................
E3LNW1_CAERE/165-243                 ........YKTNQDCVTNAPIHKNQT.FGYCDPETGKVFIM.S.EMSFHNQKNKK-LNS.....FCFTGRDCGQsfgmDN..VCMR..........VSNVTLQCYINP..................................
A0A2G5UNF3_9PELO/159-231             ........FTTHRKCSEYDAPPLR--.NVFCRRDTGTWAIL.G.EFRINGTENVV-TER.....YCTMNDDCSP....ST..VCVL..........VSDAVGLCYEDP..................................
G0MUN8_CAEBE/429-512                 ........FLTNTPCDPTKPLERVYQ.WSYCDPDTEKIMIL.G.RKAPNGKMLDE-ETR.....TCL-------....--..----..........------------kvwesnepqswamitvllvcilgiiiifmcmptp
A0A2G5SGY1_9PELO/549-626             ........YYSNLTCNDTSDLPESMD.MIYCDPYRNTVTRM.T.RNDKWWSPILAAANV.....YCEKNEDCTKy..sSS.lVCVK..........EQKDLQRCYT--y.................................
A0A2G5V6V7_9PELO/589-641             ........YLTNAPCDPTKPLDIQYI.WAYCDEKEEKVMVM.G.GRNWDGKELEW-QKT.....RCDV------....--..----..........------------tv................................
A0A2G5VKS6_9PELO/460-537             ........YETEFPCNPANPIQPGFS.YAFCNADTKKLIIV.G.KYHNNGDSMTKVSGS.....KCTINADCSPd..gSS..VCVY..........ENDKNHVCYYNP..................................
E3MVT0_CAERE/506-583                 ........YHTEFPCDPKNPIPPGFS.YVFCNSDTKKLIVV.G.KFHDNGDKMTKVSGS.....KCTINADCSSd..gGS..VCVY..........ENDKNHVCYYNP..................................
A0A261BNH1_9PELO/202-280             ........YRTNQDCVTNAPIHKNTK.FGYCDPETGKVFIM.S.EMNFHNQKNKK-LNS.....FCFTGRDCGQsfgmDN..VCMR..........VSNVTLQCYINP..................................
Q21247_CAEEL/270-359                 ........YITRVQCDAKCKIPINWA.HAFCDSKLGKIVFIgT.EFIFSTKPQHDDHRKmpkprKCSINLHCTN....GD..VCVIgwir..deknKLTPSAECLPNP..................................
G0NZ63_CAEBE/490-567                 ........YRTEFPCNPDTAVPNGFS.YAFCNPEDKKLVIM.G.NFHDNGDKMTKVSGK.....KCTINADCSSd..aSS..VCIY..........ENSQSHVCYFNP..................................
A0A261BXA4_9PELO/192-266             ........YISNFSCAPGNPIPPGFQ.FAYCSKASETIAYL.G.IVDKCGHIQHIVKNS.....TCDLDTDCPL....GS..ICVR..........-TIADGVCFKDP..................................
A0A2G5SH50_9PELO/549-626             ........YYSNLTCNDTSDLPESMD.MIYCDPYRNTVTRM.T.RNDKWWSPILAAANV.....YCEKNEDCTKy..sSS.lVCVK..........EQKDLQRCYT--y.................................
G0NDI2_CAEBE/644-721                 .......y-YEDLNCTDTIDLPPKMD.MVYCDPIRHVVTRA.S.RGDWMNSRTVAAFYT.....YCSSNDNCTDi..sSS.lVCVQ..........EKDGLNRCH---sy................................
A0A8R1DQ48_CAEJA/646-723             ........FETEFPCDPKKPLPSQFA.WSFCNSETKKIIVV.G.LFHANGDKLTEKSST.....QCDVNDDCSPd..gSS..VCVY..........KTNKEHTCFYNP..................................
G0MLF6_CAEBE/78-153                  ........YETNIPCDPRQPI-RRVS.WSFCNNLTRKVILLsG.EMY---EELTKAGEN.....ECENNNNCTM...iGS..VCAWg........sVNSEKGTCIQNP..................................
Q20917_CAEEL/300-378                 ........YRTHQKCTNKTIIRDDQR.FGYCDPKTGRVFIM.S.ELNFHGQRNKE-LSS.....YCNTARDCGRsfgmDN..VCVR..........MNKETLKCFSNP..................................
G0NSK1_CAEBE/144-215                 ........YSLNVRCRNNETPPF--R.NTFCRRDTERLAIL.G.ETRVNGTKNVE-TER.....FCVSNLDCSL....DS..VCVF..........-STTIGRCLLDP..................................
A0A261APN4_9PELO/157-231             ........FQTNMDCNANEEVDQKFD.FMFCHNETGNLWVM.G.QYNVNGDEVIK-HWT.....HCNTNNDCGE....GL..VCVK..........EDLCRYRCYDDP..................................
A8XGB2_CAEBR/401-478                 ........YETEFPCNPANPIQPGFS.YAFCNADTKKLIIV.G.KFHNNGDSMTKVSGS.....KCTINADCSPd..gSS..VCVY..........ENDKNHVCYYNP..................................
G0NAR9_CAEBE/116-186                 ........YVTRVDCASFCPLPPDWL.YAFCDPITKKVAFI.GlELSYSNQKHRDYFWKde.pkYCETNESVK-....--..----..........------------sfsgvsnvi.........................
G0MS20_CAEBE/209-287                 .......h-KTNRRCTNNTVIPKNQV.YGYCDPESGKVFIM.G.QLNDKNQSNVA-LPF.....YCRSNRDCGKsfsmNK..VCVR..........MDANYLRCYHNP..................................
A0A2G5VKQ2_9PELO/457-534             ........YETEFPCNPANPIQPGFS.YAFCNADTKKLIIV.G.KYHNNGDSMTKVSGS.....KCTINADCSPd..gSS..VCVY..........ENDKNHVCYYNP..................................
A8XUA2_CAEBR/56-95                   lpllgepk------------------.--------------.-.---------CS-SDS.....DCMQDSDCYP....GY..ICVR..........-TIDEGMCFKNP..................................
A0A2G5U630_9PELO/171-245             ........FETNISCSTERRVSRQYS.FMFCDNQTGHLWFM.G.QYNVNGDEVTR-HWT.....HCQKNKDCGE....GH..VCVK..........EDLGRFRCYDDP..................................
O01600_CAEEL/467-543                 ........YLTNYPCDANKPIPSQFStYAFCDPDTNRVGIL.G.KRHLTGEERTEVKGS.....ACSSNKDCKS....GT..VCVY..........VNINKHVCYYHP..................................
A0A8R1HIX7_CAEJA/222-300             ........YRTRFKCTNSTKVPLRYK.RGYCNPKTGTIWIM.G.SVNFKGQPIKQ-LNS.....MCMANKDCGGyvghDN..VCVR..........HHKRRLYCYINP..................................
A0A2G5V734_9PELO/588-640             ........YLTNAPCDPTKPLDIQYI.WAYCDEKEEKVMVM.G.GRNWDGKELEW-QKT.....RCDV------....--..----..........------------tv................................
A0A8R1HU98_CAEJA/111-200             ........YVTRVKCNPLCKLDRKWA.WSYCDPEMRRIVFVgS.EPMYSKEKYIDYELKv..akKCRDYRSCKN....GE..ICLAteggwsekmqQLSAANECWPNP..................................
E3M6C4_CAERE/169-243                 ........FQTNMDCNANEEVDQKFD.FMFCHNDTGNLWVM.G.QYNVNGDEVIK-HWT.....HCNTNNDCGE....GL..VCVK..........EDLCRYRCYDDP..................................
A0A2G5U6M3_9PELO/178-252             ........FETNISCSTERRVSRQYS.FMFCDNQTGHLWFM.G.QYNVNGDEVTR-HWT.....HCQKNKDCGE....GH..VCVK..........EDLGRFRCYDDP..................................
A0A261BG55_9PELO/445-522             ........YHTEFPCDPKNPIPSGFS.YVFCNSDTKKLVVV.G.KFHDNGDKMTKVSGS.....KCTINADCSSd..gGS..VCVY..........ENDKNHVCYYNP..................................
A0A2G5U626_9PELO/161-235             ........FETNISCSTERRVSRQYS.FMFCDNQTGHLWFM.G.QYNVNGDEVTR-HWT.....HCQKNKDCGE....GH..VCVK..........EDLGRFRCYDDP..................................
G0MXQ1_CAEBE/167-241                 ........YTSNFSCVPGRPILPGFQ.FAFCSNISRTIAYL.G.VVDKCGQIQHISKYS.....RCQRDSDCFP....GG..VCVW..........-IVDEGTCFRNP..................................
A0A8R1E0N8_CAEJA/166-238             .....fpt----MYCDGFTDIPDHFA.FVYCDPQKQYTVRI.S.RS-DAWNQHTKATDK.....FCTTNRDCDS....TM..VCVR..........ETLDVRRCYT--y.................................
H2L2B6_CAEEL/163-196                 ........FRTNMDCFSTEKVDTKYN.FMFCHNETD-----.-.---------------.....----------....--..----..........------------dghelrl...........................
A0A8R1DR07_CAEJA/634-711             ........FETEFPCDPKKPLPSQFA.WSFCNSETKKIIVV.G.LFHANGDKLTEKSST.....QCDVNDDCSPd..gSS..VCVY..........KTNKEHTCFYNP..................................
A0A2G5TJX7_9PELO/148-222             ........YVSNFSCVPGKPLPPGFQ.FSYCSDISKTVTYL.G.VVNSCGDIQNIHKYS.....KCHRDSDCYP....GY..ICVR..........-TIVEGMCFKNP..................................
A0A8R1I946_CAEJA/67-141              ........YTSSYRCNPKELAPPGFV.FAYCSPFSSTVTYV.G.LINKCGEFQHMSANV.....KCSSSADCAS....GY..VCVR..........-MIEDGICFWDP..................................
A0A8R1IGJ3_CAEJA/131-205             ........FRTNMDCYTHQQLESRYN.FMFCHNLTGNLWVI.G.RLNVNGDEIIH-HWN.....QCEINDDCGE....GS..VCVK..........ENLCRYRCYVDP..................................
A0A2G5TJX3_9PELO/152-226             ........YVSNFSCVPGKPLPPGFQ.FSYCSDISKTVTYL.G.VVNSCGDIQNIHKYS.....KCHRDSDCYP....GY..ICVR..........-TIVEGMCFKNP..................................
E3LN37_CAERE/526-603                 ........YYSNLSCTDTFDLPDDMG.MIYCDPKRKVVTRM.T.RGDSWFGPIIAIQNM.....YCSSNKNCTEi..sDS.lVCVR..........EMNNLQRCH---ty................................
E3LUN1_CAERE/180-254                 ........YISNFSCSPGKPIPPGFQ.FAYCSKASETIAYL.G.VVDKCGRIQHIVNDS.....KCVFDFDCPP....GN..ICVR..........-TTADGVCFKDP..................................
A0A8R1HI25_CAEJA/176-254             ........YRTRFKCTNSTKVPLRYK.RGYCNPKTGTIWIM.G.SVNFKGQPIKQ-LNS.....MCMANKDCGGyvghDN..VCVR..........HHKRRLYCYINP..................................
E3LRG6_CAERE/563-638                 ........YETNASCDPTEPLDAVYQ.WAYCDEETEKIVVL.G.NRSWGGGEEVEWEMR.....RCSVNSDCGN...pKY..LCVH..........MSYGLRYC----vls...............................
G0N4K2_CAEBE/880-936                 ........FLTNTPCDPTKPLERVYQ.WSYCDPETEKIMIL.G.RKAPNGKMLEE-ETR.....TC--------....--..----..........------------lkvwesne..........................
H2L2B7_CAEEL/163-237                 ........FRTNMDCFSTEKVDTKYN.FMFCHNETGNLWVI.G.QLNLNGEEVMK-HWK.....QCDLNTDCGE....GL..VCVK..........EDLCRYRCYEDP..................................
E3NNZ2_CAERE/154-228                 ........FQTNMDCNANEEVDQKFD.FMFCHNDTGNLWVM.G.QYNVNGDEVIK-HWT.....HCNTNNDCGE....GL..VCVK..........EDLCRYRCYDDP..................................
A8XMS2_CAEBR/94-166                  ........FTTQRKCSDYDAPPLR--.NVFCRRDIGKWAIL.G.EFRVNGTENVV-PER.....YCTRNIDCSP....ST..VCVL..........VSDAIGLCYEDP..................................
A8X701_CAEBR/321-399                 ........YETNIDCTDSTVISKTLL.FGYCDPLTKKIFIM.S.EKNYEGQDNKM-LDA.....FCMSGRDCGRs..yGTenVCVR..........TSTQTPRCFINP..................................
A0A8R1HGX5_CAEJA/132-210             ........YRTRFKCTNSTKVPLRYK.RGYCNPKTGTIWIM.G.SVNFKGQPIKQ-LNS.....MCMANKDCGGyvghDN..VCVR..........HHKRRLYCYINP..................................
A0A2G5TFD1_9PELO/328-406             ........YETNLDCTDSTLIPRSLL.FGYCDPQTKKIFIM.S.EKNYEGQDNKM-LDA.....FCMSGRDCGRs..yGTenVCVR..........TSTQTPRCFINP..................................
A0A8R1HU98_CAEJA/71-109              ........YVTRVKCNPLCKLDRKWA.WSYCDPEMRRIVFV.D.---------------.....----------....--..----..........------------hsirkk............................
A0A8R1HTE7_CAEJA/73-162              ........YVTRVKCNPLCKLDRKWA.WSYCDPEMRRIVFVgS.EPMYSKEKYIDYELKv..akKCRDYRSCKN....GE..ICLAteggwsekmqQLSAANECWPNP..................................
A8XGB0_CAEBR/445-522                 ........YETEFPCNPANPIQPGFS.YAFCNADTKKLIIV.G.KFHNNGDSMTKVSGS.....KCTINADCSPd..gSS..VCVY..........ENDKNHVCYYNP..................................
A0A8R1HTE7_CAEJA/33-71               ........YVTRVKCNPLCKLDRKWA.WSYCDPEMRRIVFV.D.---------------.....----------....--..----..........------------hsirkk............................
A0A261C0X5_9PELO/551-624             ........YETNASCDPTEPLDTVYQ.WAYCDEETEKIVVI.G.NKSWDGGEELE--KR.....RCSVNSDCGN...pKY..LCVH..........MSYGLRYC----vls...............................
A0A8R1IJD4_CAEJA/137-211             ........FRTNMDCYTHQQLESRYN.FMFCHNLTGNLWVI.G.RLNVNGDEIIH-HWN.....QCEINDDCGE....GS..VCVK..........ENLCRYRCYVDP..................................
G0NWL1_CAEBE/490-567                 ........YRTEFPCNPDTAVPNGFS.YAFCNPEDKKLVIM.G.NFHDNGDKMTKVSGK.....KCTINADCSSd..aSS..VCIY..........ENSQSHVCYFNP..................................
A8WQR1_CAEBR/147-221                 ........FETNISCSTEQSVSGPYS.FMFCNNRTGHLWFM.G.QYNVNGDEVTR-HWT.....HCQFNKDCGK....GH..VCVK..........EDLARFRCYDDP..................................
#=GC seq_cons                        ........YpTshsCssspslstpas.auaCcscTp+lhlh.G.phshsGpphpc.pts.....pCphNpDCst....up..VCVh...........s.tphhCa.sP..................................
//