GenomeNet

Database: Pfam
Entry: Dicty_REP
LinkDB: Dicty_REP
Original site: Dicty_REP 
#=GF ID   Dicty_REP
#=GF AC   PF05086.14
#=GF DE   Dictyostelium (Slime Mold) REP protein
#=GF PI   Dict_REP; 
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_6278 (release 7.7)
#=GF GA   20.90 20.90;
#=GF TC   20.90 21.00;
#=GF NC   20.80 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10366530
#=GF RT   Mechanism of action of the Rep protein from the Dictyostelium
#=GF RT   Ddp2 plasmid family. 
#=GF RA   Shammat IM, Welker DL; 
#=GF RL   Plasmid 1999;41:248-259.
#=GF DR   INTERPRO; IPR007778;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of REP proteins from Dictyostelium (Slime
#=GF CC   molds). REP protein is likely involved in transcription
#=GF CC   regulation and control of DNA replication, specifically
#=GF CC   amplification of plasmid at low copy numbers. The formation of
#=GF CC   homomultimers may be required for their regulatory activity [1].
#=GF SQ   4
#=GS A0A4T0X4U8_9ASCO/80-192  AC A0A4T0X4U8.1
#=GS F1A0F2_DICPU/1-877       AC F1A0F2.1
#=GS F0Z7Z9_DICPU/4-179       AC F0Z7Z9.1
#=GS A0A2N5SJG4_9BASI/3-183   AC A0A2N5SJG4.1
A0A4T0X4U8_9ASCO/80-192             ilyalhslgfenyaeilriyla------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....--------------------------------------KYRIFELD.............EVEKRRAKYIARKNKLQKEKLNNSTSNTNTTTTTTTTTTTTTNTITNNNDNNDLSNSQ------------------.........--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...---------------------------------.----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------yweldsplsprssstqaspqnseil..............................................................
F1A0F2_DICPU/1-877                  ......................KELIPWDRSIDIYYKLLSTYAPVEKQQ-KSDVNIMSCYFSSDIVVLREIVKKILSSIR-----PDCFKVTNVFPKTNQ-F--LNFKNNKSFDLDSAFRYRLDAMGKNIIDDCDQAILVIDHLSRIYDSHIFSKNSLPTFKSLETLVTKYGYKISHRRFIATEWYAFLQQFKKECGGSKDFrldgEEVSKNNSPDLIGLFSFIHGVHT-NQSEEEIKISNIFSIFPFLDLEqdnvlpiytrsrpNTKSIETPSSLNKETTEITTSTPSYIRIKDIMQITTTNATATPIPTQKATKVQDKNIESIPITTPQLDKKRKAIEP.........---TPRISTRKTNSLQHVRVNSLSLK--TNNDAIEIDDEKTDIIISDKIKNIFTSIDKS--VSNASDVKSLFNMLQKKIYDSQSLYSLLLKNKSRDSVILTNETLELAEAIDYDEIHLELLTDEVYNMASVFLISKNKNIIVPTIVDTDKLGFLWIPIVDGKVSTSLYIVPNETILDTSKVKAITKFIQMIISLADIVSFLKNQRIELPLFKSVCSDLsMELDTIILRIEDLENQIEQQIHKYhsFRSRMANTESlneQSVALITSEKEKINQIRSFVDSHHYINFSRSQDpCLSLVDTRLSTLVLEYNPSTIQHIAGFFDLCSLMVSKTDISGFNLQIASIMSSFLPTNIKNLSFERETALKEKLAMTFSNSTVLNETFRIQNVKSVKRYLTISVTNKTFNACRIFAFSDVKKGFSISNLRNIFKENTKSYSRYIEYFNGTHEIFAFFAAPCIFKITNIQYSAPEIVSDRLLSRKIKSFTFRNLSPILVDIKVGQEIITSVKPDTTQNVQIESNEFEFTVSCMKFSFGTTIISKNRLNLLTDKET-EINNRKNiLLDKINKCEELKKKFIKELD------------------------------------------k......................................................................................
F0Z7Z9_DICPU/4-179                  ..........kgagslneqsva------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....----------------------------------------------.............----------------------------------------------------------------------------.........--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...----LITSEKEKINQIRSFEDSHHYINFSRSQNpCLSLVDTRLSTLVLEYNPSTIQHIAGFFDLCSLMVSKTDISGFNLQIASIMSSFLPTNIKNLSFERETALKEKLAMTFSNSTVLNETFRIQNVKSVKRYLTISVTNKTFNACRIFAFSDVKKGFSISNLNYLF---------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------y......................................................................................
A0A2N5SJG4_9BASI/3-183              ..............hplspneq------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....---------------------------------------------E.............GNEEQDNKTESEENNNNKQNQREREGKNQGITTTTTTTTTTTETPTRKRLARD-DTLKQHLNPSTRPNTNNSRSSSyhhhtpkqqT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.------------------------..----------...---------------------------------.----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------ftislsdqphliptktklltelktatqqldqnhleslmlslirelssklnqsqhdlktsqleltglknllintysvgsgeierclvr
#=GC seq_cons                       ..............p..p...t.....................................................................................................................................................................................................................................-.............tscp.cs....pcpp.phpp.p.p..p.pshhphTTTssTsT.h.Tppt.t.p.ps.p....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................a......................................................................................
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