#=GF ID EFhand_Ca_insen
#=GF AC PF08726.10
#=GF DE Ca2+ insensitive EF hand
#=GF PI efhand_Ca_insen;
#=GF AU Mistry J;0000-0003-2479-5322
#=GF SE pdb_1h88
#=GF GA 20.80 20.80;
#=GF TC 20.80 20.80;
#=GF NC 20.70 20.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 11573089
#=GF RT Ca2+-independent binding of an EF-hand domain to a novel motif
#=GF RT in the alpha-actinin-titin complex.
#=GF RA Atkinson RA, Joseph C, Kelly G, Muskett FW, Frenkiel TA,
#=GF RA Nietlispach D, Pastore A;
#=GF RL Nat Struct Biol. 2001;8:853-857.
#=GF DR INTERPRO; IPR014837;
#=GF DR SCOP; 1h88; fa;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC EF hands are helix-loop-helix binding motifs involved in the
#=GF CC regulation of many cellular processes. EF hands usually bind to
#=GF CC Ca2+ ions which causes a major conformational change that allows
#=GF CC the protein to interact with its designated targets. This
#=GF CC domain corresponds to an EF hand which has partially or entirely
#=GF CC lost its calcium-binding properties. The calcium insensitive EF
#=GF CC hand is still able to mediate protein-protein recognition [1].
#=GF SQ 1892
#=GS T1GCF3_MEGSC/2122-2192 AC T1GCF3.1
#=GS A0A1S3M5F3_SALSA/2417-2486 AC A0A1S3M5F3.1
#=GS A0A1I8A3G2_9BILA/81-136 AC A0A1I8A3G2.1
#=GS G1T346_RABIT/2450-2519 AC G1T346.2
#=GS A0A2I4DAL0_9TELE/779-845 AC A0A2I4DAL0.1
#=GS A0A162QG52_9CRUS/825-891 AC A0A162QG52.1
#=GS A6QTN5_AJECN/536-574 AC A6QTN5.1
#=GS A0A0D7B6D0_9AGAR/555-621 AC A0A0D7B6D0.1
#=GS A0A2I2V4J9_FELCA/817-883 AC A0A2I2V4J9.1
#=GS A0A0V1P021_9BILA/2350-2417 AC A0A0V1P021.1
#=GS A0A2I2UNZ9_FELCA/844-910 AC A0A2I2UNZ9.1
#=GS G0RD66_HYPJQ/557-628 AC G0RD66.1
#=GS A0A091ITG1_CALAN/827-893 AC A0A091ITG1.1
#=GS A0A166A722_9HOMO/553-619 AC A0A166A722.1
#=GS M3X6F7_FELCA/841-907 AC M3X6F7.2
#=GS A0A2I0MNU8_COLLI/606-672 AC A0A2I0MNU8.1
#=GS A0A2A2LXT6_9BILA/2368-2438 AC A0A2A2LXT6.1
#=GS S9XHZ6_CAMFR/961-1027 AC S9XHZ6.1
#=GS A0A287A4Q7_PIG/841-907 AC A0A287A4Q7.1
#=GS A0A218VB10_9PASE/797-863 AC A0A218VB10.1
#=GS A0A287DBD5_ICTTR/2407-2476 AC A0A287DBD5.1
#=GS B6QFX9_TALMQ/554-625 AC B6QFX9.1
#=GS A0A1S3KXD9_SALSA/2439-2508 AC A0A1S3KXD9.1
#=GS A0A1S3WGD0_ERIEU/2402-2471 AC A0A1S3WGD0.1
#=GS G1S4J1_NOMLE/841-907 AC G1S4J1.3
#=GS A2QGU9_ASPNC/559-630 AC A2QGU9.1
#=GS A0A2I2YSG9_GORGO/841-907 AC A0A2I2YSG9.1
#=GS A0A287D3N7_ICTTR/863-929 AC A0A287D3N7.1
#=GS V2XQV6_MONRO/557-623 AC V2XQV6.1
#=GS A0A182VGE2_ANOME/2343-2416 AC A0A182VGE2.1
#=GS F1RUT3_PIG/777-843 AC F1RUT3.1
#=GS F6UPM7_HORSE/2391-2460 AC F6UPM7.1
#=GS F5HMN8_ANOGA/827-893 AC F5HMN8.1
#=GS A0A0V1DH61_TRIBR/2279-2348 AC A0A0V1DH61.1
#=GS F1RNB8_PIG/2324-2392 AC F1RNB8.3
#=GS B2AXE1_PODAN/819-890 AC B2AXE1.1
#=GS A0A0J6Y5M8_COCIT/559-630 AC A0A0J6Y5M8.1
#=GS G1LBL4_AILME/2400-2469 AC G1LBL4.1
#=GS A0A1W4VS21_DROFC/825-891 AC A0A1W4VS21.1
#=GS G3PEI1_GASAC/845-911 AC G3PEI1.1
#=GS U3J5Y3_ANAPL/2407-2476 AC U3J5Y3.1
#=GS A0A2K5HT55_COLAP/2294-2363 AC A0A2K5HT55.1
#=GS A0A0Q9WTR0_DROWI/827-893 AC A0A0Q9WTR0.1
#=GS A0A1S3R7B3_SALSA/826-892 AC A0A1S3R7B3.1
#=GS B3S0V2_TRIAD/810-876 AC B3S0V2.1
#=GS T0LZM9_COLGC/707-778 AC T0LZM9.1
#=GS F6QM83_ORNAN/261-306 AC F6QM83.1
#=GS A0A0D2JJ48_9EURO/569-640 AC A0A0D2JJ48.1
#=GS A0A1U7R454_MESAU/2407-2476 AC A0A1U7R454.1
#=GS A0A182QPI6_9DIPT/2343-2416 AC A0A182QPI6.2
#=GS A0A1S3DD30_DIACI/1960-2030 AC A0A1S3DD30.1
#=GS B0X640_CULQU/2341-2411 AC B0X640.1
#=GS H3C0G3_TETNG/2366-2435 AC H3C0G3.1
#=GS A0A0P5ZGU3_9CRUS/2343-2413 AC A0A0P5ZGU3.1
#=GS J9B511_WUCBA/695-761 AC J9B511.1
#=GS A0A0L0HAR8_SPIPN/578-639 AC A0A0L0HAR8.1
#=GS A0A1L9V8D4_ASPGL/559-630 AC A0A1L9V8D4.1
#=GS A0A1S3KXK2_SALSA/2423-2492 AC A0A1S3KXK2.1
#=GS G5AMB0_HETGA/863-929 AC G5AMB0.1
#=GS B7P1U8_IXOSC/2297-2367 AC B7P1U8.1
#=GS A0A151J4T0_9HYME/2362-2432 AC A0A151J4T0.1
#=GS A0A0G2ICF2_9EURO/635-706 AC A0A0G2ICF2.1
#=GS U3JFB5_FICAL/2440-2509 AC U3JFB5.1
#=GS A0A2B7XN82_9EURO/631-702 AC A0A2B7XN82.1
#=GS Q0UG56_PHANO/635-706 AC Q0UG56.1
#=GS W2SGT5_NECAM/919-985 AC W2SGT5.1
#=GS L5KU80_PTEAL/417-455 AC L5KU80.1
#=GS Q9XVU8_CAEEL/827-893 AC Q9XVU8.1
#=GS A0A088ACE3_APIME/2362-2432 AC A0A088ACE3.1
#=GS A0A1D5QZP3_MACMU/844-910 AC A0A1D5QZP3.1
#=GS A0A1E3IZB1_9TREE/662-740 AC A0A1E3IZB1.1
#=GS A0A2K5N6P9_CERAT/822-888 AC A0A2K5N6P9.1
#=GS U4LQQ6_PYROM/553-619 AC U4LQQ6.1
#=GS G0PGG9_CAEBE/854-920 AC G0PGG9.1
#=GS K7J3F4_NASVI/2350-2420 AC K7J3F4.1
#=GS F7DZI2_HORSE/809-875 AC F7DZI2.1
#=GS A0A158NIL3_ATTCE/2362-2432 AC A0A158NIL3.1
#=GS A0A1S3NQW9_SALSA/827-893 AC A0A1S3NQW9.1
#=GS A0A1J1J412_9DIPT/2353-2423 AC A0A1J1J412.1
#=GS A0A2I3GFB3_NOMLE/571-637 AC A0A2I3GFB3.1
#=GS A0A0G2K5U9_RAT/841-907 AC A0A0G2K5U9.1
#=GS A0A0A0MU58_PAPAN/861-927 AC A0A0A0MU58.2
#=GS A0A1S3G0R0_DIPOR/713-779 AC A0A1S3G0R0.1
#=GS A0A1U7SRU8_TARSY/810-876 AC A0A1U7SRU8.1
#=GS D2A2X1_TRICA/827-893 AC D2A2X1.2
#=GS A0A2I3HSR9_NOMLE/851-917 AC A0A2I3HSR9.1
#=GS T0QBC9_9STRA/816-885 AC T0QBC9.1
#=GS A0A2D0SYG2_ICTPU/2395-2464 AC A0A2D0SYG2.1
#=GS A0A286ZXS0_PIG/2320-2389 AC A0A286ZXS0.1
#=GS G3RK88_GORGO/817-883 AC G3RK88.2
#=GS H2Y432_CIOSA/598-664 AC H2Y432.1
#=GS A3KGU5_MOUSE/2387-2456 AC A3KGU5.1
#=GS A0A182H9F8_AEDAL/2343-2413 AC A0A182H9F8.1
#=GS A0A091VWV9_OPIHO/782-848 AC A0A091VWV9.1
#=GS F6WL10_CALJA/814-880 AC F6WL10.1
#=GS A0A091KV20_9GRUI/783-849 AC A0A091KV20.1
#=GS Q16EQ1_AEDAE/2343-2413 AC Q16EQ1.1
#=GS G0M7G2_CAEBE/2356-2426 AC G0M7G2.1
#=GS G2X0G5_VERDV/746-817 AC G2X0G5.1
#=GS G3W7Y5_SARHA/2348-2414 AC G3W7Y5.1
#=GS F7GNT1_CALJA/752-818 AC F7GNT1.1
#=GS A0A2I2ZSD9_GORGO/802-868 AC A0A2I2ZSD9.1
#=GS H2XNV5_CIOIN/873-923 AC H2XNV5.1
#=GS F4P7B2_BATDJ/552-613 AC F4P7B2.1
#=GS C4QKY6_SCHMA/335-404 AC C4QKY6.2
#=GS A0A2I3S7A0_PANTR/622-688 AC A0A2I3S7A0.1
#=GS A0A084WSW3_ANOSI/2339-2412 AC A0A084WSW3.1
#=GS G3VUD5_SARHA/807-873 AC G3VUD5.1
#=GS A0A1V6UPB2_9EURO/559-630 AC A0A1V6UPB2.1
#=GS G7NWN5_MACFA/783-849 AC G7NWN5.1
#=GS F4PP47_CAVFA/793-854 AC F4PP47.1
#=GS A0A2I4CQK0_9TELE/840-906 AC A0A2I4CQK0.1
#=GS A0A1I7T412_9PELO/827-893 AC A0A1I7T412.1
#=GS A0A1W4XQF4_AGRPL/2358-2428 AC A0A1W4XQF4.1
#=GS G3SM74_LOXAF/822-888 AC G3SM74.1
#=GS E9I8D6_SOLIN/2347-2417 AC E9I8D6.1
#=GS A0A1L9WGN9_ASPAC/559-630 AC A0A1L9WGN9.1
#=GS M3W4T6_FELCA/2376-2445 AC M3W4T6.2
#=GS A0A2I3HE42_NOMLE/453-519 AC A0A2I3HE42.1
#=GS A0A2I2ZUB0_GORGO/844-910 AC A0A2I2ZUB0.1
#=GS A0A1U7RUW5_ALLSI/2407-2476 AC A0A1U7RUW5.1
#=GS G3QXD1_GORGO/2402-2471 AC G3QXD1.2
#=GS B4H5R3_DROPE/225-295 AC B4H5R3.1
#=GS A0A068XSV2_HYMMI/844-910 AC A0A068XSV2.1
#=GS SPTA1_HUMAN/2350-2418 AC P02549.5
#=GS A0A0R3WDT2_TAEAS/2347-2417 AC A0A0R3WDT2.2
#=GS A0A099YXL3_TINGU/2389-2458 AC A0A099YXL3.1
#=GS G3UTU7_MELGA/821-887 AC G3UTU7.1
#=GS A0A1U7UKH2_TARSY/216-249 AC A0A1U7UKH2.1
#=GS W2SZM5_NECAM/2402-2472 AC W2SZM5.1
#=GS SPTN1_RAT/2402-2471 AC P16086.2
#=GS M2MJT8_BAUCO/555-626 AC M2MJT8.1
#=GS A0A2K5JXF2_COLAP/836-902 AC A0A2K5JXF2.1
#=GS A0A261CQN2_9PELO/2362-2432 AC A0A261CQN2.1
#=GS W5KV30_ASTMX/826-892 AC W5KV30.1
#=GS G3UR37_MELGA/622-688 AC G3UR37.1
#=GS C1GJ47_PARBD/628-699 AC C1GJ47.1
#=GS A0A158NIL4_ATTCE/2347-2417 AC A0A158NIL4.1
#=GS A0A0D2DSJ6_9EURO/569-640 AC A0A0D2DSJ6.1
#=GS A0A1D5Q1Y7_MACMU/2353-2422 AC A0A1D5Q1Y7.1
#=GS A0A091ITT8_EGRGA/782-848 AC A0A091ITT8.1
#=GS A0A0Q9WZJ5_DROMO/825-891 AC A0A0Q9WZJ5.1
#=GS A0A0N1NYH7_9EURO/569-640 AC A0A0N1NYH7.1
#=GS F1QER4_DANRE/139-205 AC F1QER4.1
#=GS A3KGU9_MOUSE/2428-2497 AC A3KGU9.2
#=GS A0A132AJL6_SARSC/794-860 AC A0A132AJL6.1
#=GS A0A1E4U0P7_PACTA/583-641 AC A0A1E4U0P7.1
#=GS A0A2I2UB74_FELCA/2435-2504 AC A0A2I2UB74.1
#=GS Q05AR8_XENTR/815-881 AC Q05AR8.1
#=GS A0A2I4DAK6_9TELE/779-845 AC A0A2I4DAK6.1
#=GS G3SYC3_LOXAF/786-852 AC G3SYC3.1
#=GS G3W7Y3_SARHA/2338-2404 AC G3W7Y3.1
#=GS A0A152A3U3_9MYCE/1213-1274 AC A0A152A3U3.1
#=GS A0A1S3M5J3_SALSA/2401-2470 AC A0A1S3M5J3.1
#=GS T1FP58_HELRO/815-881 AC T1FP58.1
#=GS A0A2I3TXD4_PANTR/2407-2476 AC A0A2I3TXD4.1
#=GS A0A1W0WJU5_HYPDU/903-969 AC A0A1W0WJU5.1
#=GS A0A093C316_TAUER/826-892 AC A0A093C316.1
#=GS A0A0F8CQE0_LARCR/852-918 AC A0A0F8CQE0.1
#=GS A1DF00_NEOFI/559-630 AC A1DF00.1
#=GS A0A1Y1XRH3_9FUNG/583-647 AC A0A1Y1XRH3.1
#=GS A0A182JZ68_9DIPT/2343-2416 AC A0A182JZ68.2
#=GS W5M0C7_LEPOC/699-765 AC W5M0C7.1
#=GS H3DJZ7_TETNG/93-160 AC H3DJZ7.1
#=GS A0A0C9X859_9AGAR/554-620 AC A0A0C9X859.1
#=GS A0A0R3P5Q6_DROPS/2354-2424 AC A0A0R3P5Q6.1
#=GS A0A091RWT0_NESNO/783-849 AC A0A091RWT0.1
#=GS A0A1S3FLH1_DIPOR/2101-2170 AC A0A1S3FLH1.1
#=GS A0A1R3RE92_ASPC5/559-630 AC A0A1R3RE92.1
#=GS T1IPX7_STRMM/884-950 AC T1IPX7.1
#=GS A0A183KLP7_9TREM/955-1024 AC A0A183KLP7.1
#=GS F7HLQ1_MACMU/2402-2471 AC F7HLQ1.2
#=GS A0A2I3LMG7_PAPAN/2387-2456 AC A0A2I3LMG7.1
#=GS A0A093FTA5_DRYPU/827-893 AC A0A093FTA5.1
#=GS A0A218UIK4_9PASE/822-888 AC A0A218UIK4.1
#=GS A0A1C1XK79_9PEZI/785-856 AC A0A1C1XK79.1
#=GS A0A0N5AEH5_9BILA/884-950 AC A0A0N5AEH5.1
#=GS G7PAK8_MACFA/874-926 AC G7PAK8.1
#=GS A0A2K5MZS2_CERAT/2331-2400 AC A0A2K5MZS2.1
#=GS F7GFZ5_CALJA/835-901 AC F7GFZ5.1
#=GS G3Q5J2_GASAC/784-850 AC G3Q5J2.1
#=GS A0A096NVR2_PAPAN/844-910 AC A0A096NVR2.1
#=GS A0A1S3FK07_DIPOR/830-896 AC A0A1S3FK07.1
#=GS A0A1D5QAI4_MACMU/2387-2456 AC A0A1D5QAI4.1
#=GS A0A1A9V2Y6_GLOAU/2619-2689 AC A0A1A9V2Y6.1
#=GS ACTN1_RAT/822-888 AC Q9Z1P2.1
#=GS H9JEK1_BOMMO/2386-2457 AC H9JEK1.1
#=GS T1ELU5_HELRO/2342-2411 AC T1ELU5.1
#=GS F1RHL9_PIG/824-890 AC F1RHL9.1
#=GS C0NNI1_AJECG/643-714 AC C0NNI1.1
#=GS H2MBY2_ORYLA/2412-2481 AC H2MBY2.1
#=GS A0A182YB86_ANOST/827-893 AC A0A182YB86.1
#=GS A0A158PIY8_ANGCS/885-951 AC A0A158PIY8.1
#=GS A0A1S3WKS2_ERIEU/2342-2410 AC A0A1S3WKS2.1
#=GS H2SFT9_TAKRU/826-892 AC H2SFT9.1
#=GS A0A091DLC8_FUKDA/2434-2503 AC A0A091DLC8.1
#=GS A0A2I2ZTW3_GORGO/438-507 AC A0A2I2ZTW3.1
#=GS G4TNT1_SERID/551-632 AC G4TNT1.1
#=GS A0A074Z746_9PEZI/556-627 AC A0A074Z746.1
#=GS A0A0V0U051_9BILA/823-889 AC A0A0V0U051.1
#=GS A0A151XDV2_9HYME/2362-2432 AC A0A151XDV2.1
#=GS A0A0Q9WTS6_DROWI/847-913 AC A0A0Q9WTS6.1
#=GS A0A183W9T4_TRIRE/113-180 AC A0A183W9T4.1
#=GS E1BFB0_BOVIN/2402-2471 AC E1BFB0.2
#=GS A0A162K3B6_9HYPO/979-1050 AC A0A162K3B6.1
#=GS H3BAS1_LATCH/809-875 AC H3BAS1.1
#=GS A0A183S417_9TREM/125-166 AC A0A183S417.1
#=GS G3QE19_GORGO/2350-2418 AC G3QE19.2
#=GS A0A093R7I8_PHACA/827-893 AC A0A093R7I8.1
#=GS A0A0B2W457_TOXCA/2320-2390 AC A0A0B2W457.1
#=GS U3JFB7_FICAL/2407-2476 AC U3JFB7.1
#=GS A0A183CR52_GLOPA/210-239 AC A0A183CR52.1
#=GS A0A151P6Y2_ALLMI/801-867 AC A0A151P6Y2.1
#=GS C4JLF0_UNCRE/565-636 AC C4JLF0.1
#=GS Q8AX99_DANRE/828-894 AC Q8AX99.1
#=GS A0A1U7S2C6_ALLSI/2382-2451 AC A0A1U7S2C6.1
#=GS F1RI39_PIG/863-929 AC F1RI39.3
#=GS H2Q1E4_PANTR/615-681 AC H2Q1E4.2
#=GS A0A1A9ZFY2_GLOPL/3730-3800 AC A0A1A9ZFY2.1
#=GS F7IE32_CALJA/812-878 AC F7IE32.1
#=GS A0A1C7LW61_GRIFR/555-594 AC A0A1C7LW61.1
#=GS A0A2I3M229_PAPAN/608-674 AC A0A2I3M229.1
#=GS I0FW14_MACMU/817-883 AC I0FW14.1
#=GS A0A1X2I3T6_9FUNG/575-641 AC A0A1X2I3T6.1
#=GS A0A0N4VFD4_ENTVE/2327-2397 AC A0A0N4VFD4.1
#=GS A0A093UTK5_TALMA/554-604 AC A0A093UTK5.1
#=GS Q6XDA1_RAT/2316-2384 AC Q6XDA1.1
#=GS A0A1U8CL70_MESAU/2382-2451 AC A0A1U8CL70.1
#=GS A0A093DNT1_9AVES/704-770 AC A0A093DNT1.1
#=GS A7T681_NEMVE/89-155 AC A7T681.1
#=GS A0A100IMX0_ASPNG/559-630 AC A0A100IMX0.1
#=GS G2QDK3_MYCTT/555-626 AC G2QDK3.1
#=GS A0A1S3AGC3_ERIEU/863-929 AC A0A1S3AGC3.1
#=GS A0A0N5CRG6_THECL/87-153 AC A0A0N5CRG6.1
#=GS G7PP89_MACFA/831-897 AC G7PP89.1
#=GS G1TQR0_RABIT/822-888 AC G1TQR0.1
#=GS H2QG89_PANTR/841-907 AC H2QG89.1
#=GS F6UPQ8_HORSE/2411-2480 AC F6UPQ8.1
#=GS T1HHH6_RHOPR/1-57 AC T1HHH6.1
#=GS A0A0L7KUI8_9NEOP/913-969 AC A0A0L7KUI8.1
#=GS I3IYH3_ORENI/829-895 AC I3IYH3.1
#=GS A0A177DJR3_ALTAL/554-625 AC A0A177DJR3.1
#=GS A0A1U7QDU1_MESAU/785-851 AC A0A1U7QDU1.1
#=GS A0A1S3NQY7_SALSA/827-893 AC A0A1S3NQY7.1
#=GS A0A1S2ZFT4_ERIEU/830-896 AC A0A1S2ZFT4.1
#=GS A0A2I2UFC8_FELCA/752-818 AC A0A2I2UFC8.1
#=GS A0A0V0UY08_9BILA/2384-2453 AC A0A0V0UY08.1
#=GS F6R1M6_HORSE/824-890 AC F6R1M6.1
#=GS A0A1A9XH10_GLOFF/851-917 AC A0A1A9XH10.1
#=GS A0A183SH17_SCHSO/723-789 AC A0A183SH17.1
#=GS H6C5Z2_EXODN/569-640 AC H6C5Z2.1
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A0A1U7UTY1_TARSY/752-818 ...............DTDTADQVIASFKVL..A.......GD...K......N.............FITAEELR...R...E..LP...P...DQA...EYCIARMAPYQ........................GPD.........--TVPGA...LDYKSFSTALYG.......................................
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A0A0M9VSB9_9HYPO/555-626 ...............DQNTAEQVFQSFREV..A.......DG...K......P.............YVTEMDLR...H...S..LV...P...DEV..iDKLLEMMPPHN........................GPDm.......sQDRGRPQ...YDYISFMEKM--ir.....................................
ACTNA_DICDI/800-861 ..............g-TDSVESTKAAFKVM..A.......ED...K......D.............FITEAQIR...A...A..IS...D...SKQ..iDYLLASMPAVE........................---.........-----GG...FDYNSFAEKLYQ.......................................
F6QQX8_MACMU/867-933 ...............ETDTAEQVVASFKIL..A.......GD...K......N.............YITPEELR...R...E..LP...A...EQA...EYCIRRMVPYK........................GSG.........--APAGA...LDYVAFSSALYG.......................................
E4USW4_ARTGP/559-630 ...............DQNTAEQVLQSFKEV..A.......DG...K......P.............YVTELDLR...H...S..LI...P...DEL..iDNLVESMPKHT........................GPDl.......lEDRDVPK...YDYMTFMEHMM-n......................................
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A0A151JNA1_9HYME/864-930 ...............DTDTAEQVIDSFRIL..A.......GD...K......P.............YILPDELR...R...E..LP...P...DQA...EYCIQRMPPYK........................GPS.........--AVPGA...LDYRSFSTALYG.......................................
W5P9P1_SHEEP/832-893 ...............ETDTAEQVVASFKIL..A.......GD...K......N.............YITAEELR...R...E..LP...A...EQA...R-----RAPDR........................GAG.........--APAGA...LDYVAFSSALYG.......................................
A0A1B9GM09_9TREE/648-707 ...............DASSPEQLREAFRGM..A.......GD...K......P.............YVTDIDFQ...Y...A..HL...P...KET..vRFLEEIMPEER........................DPA.........-------...------------eveegqdrp..............................
A0A162V9F3_PHYB8/551-615 ...............DKSTPQQLHDSFRAI..A.......AD...K......P.............YVTELDLS...M...C..LV...P...APF..iDYLKHTMPQSR........................---.........--EEPGA...LDYSSYVMQTF-i......................................
A0A1Y3BJZ7_EURMA/271-340 ...............NISTQEEMYNAFRYI..A.......ND...R......P.............YITLEEIR...A...N..IP...W...DKV...DYCIKHMKPYV........................DPK........tNCEIKDA...YDYESFIQRLF-s......................................
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A0A0J8QQZ2_COCIT/543-614 ...............DQNTAEQVFQSFREV..A.......DG...K......P.............YVTELDLR...H...S..LI...P...EDL..iDNLLQTMPKHE........................GPDl.......lEDRDLPK...YDYITFMEHMM-n......................................
A0A087TGZ7_9ARAC/2360-2429 ...............NVRSSEEVENAFRAI.tS.......GE...R......P.............YVTAEELY...A...N..LT...K...EMA...DYCLSRMKPYE........................DKS.........GRTIPGA...YDYIDFTRTLFQ.......................................
A0A1I7VXE2_LOALO/822-888 ...............DADTVEQMIESFKIL..A.......GG...K......P.............YITAEEIR...R...E..LQ...A...DQA...EYCIQRMQQFQ........................ASN.........--GPPGS...YNYVSFSKSLYN.......................................
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A0A0P8ZSY5_DROAN/2354-2424 ...............NVQSYEEIENAFRAI.tA.......AD...R......P.............YVTKEELY...C...N..LT...K...DMA...DYCVQRMKPYS........................EPR........sGQPIKDA...LDYIDFTRTLFQ.......................................
A0A1S3M5V9_SALSA/2409-2478 ...............NVKSSEEIESAFRAL.sV.......DA...K......P.............YVTKEELY...Q...N..LS...K...EQA...DYCISHMKPYL........................DSK.........GREMPSA...FDFVEFTRSLF-v......................................
A0A0S4KIF8_BODSA/105-168 .............er--ESKAEVLRAFRQL.dA.......AD...K......G.............YVAMEDIQ...Qv.aE..LL...E...QDL..tEDELREMMEFA........................HPR........sA------...------------assqpqag...............................
A0A2C9JIY1_BIOGL/819-885 ...............DTDTAEQVMQSFKIL..A.......GD...K......P.............YITAQILR...Q...E..LP...P...DQA...EYCIQRMAPYT........................GRD.........--AVPGA...LDYMSFSTALYG.......................................
H2Q0C2_PANTR/2350-2418 ...............NIKSSDEIENAFQAL..A.......EG...K......S.............YITKEDMK...Q...A..LT...P...EQV...SFCATHMQQYM........................DPR.........GRSHLSG...YDYVGFTNSCFG.......................................
A0A2D0S9K8_ICTPU/830-896 ...............ETDTAEQVVASFRIL..A.......GD...K......P.............YIMIEELR...R...E..LP...P...EQA...DYCIARMPLYT........................GPD.........--GVPGA...LDYQAFSSALYG.......................................
A0A094KLV4_9PEZI/555-626 ...............DQNTAEQVFQSFREV..A.......DG...K......P.............YVTEMDLR...H...S..LV...P...DDV..iEKLTKIIPAHK........................GPDl.......qEDRGMPQ...YDYVSFMDHL--id.....................................
A0A072Q0C1_9EURO/569-640 ...............DQNSADQVFQSFREV..A.......DG...K......P.............YVTEMDLR...H...S..LI...P...EEL..iEDLLQSMPQHK........................GPDm.......eADRNVPK...YDYISFMQGM--ig.....................................
A0A0B2VKR6_TOXCA/595-652 ...............DADTVEQMIESFKIL..S.......SG...K......P.............FITAEELR...R...E..LP...T...DQA...EYCIERMTAYR........................D--.........-------...------------gpparlecrv.............................
A0A075AC94_9TREM/544-610 ...............DEDTAEQITQSFKVL..S.......GD...K......G.............YVTADDLR...R...Y..LP...P...DDA...EYCIKRMMRAS........................GPH.........--GDSGA...LNYEQFTLEIY-g......................................
A0A1S3JQJ4_LINUN/2354-2423 ...............NVQSSKDVEEAFRAL.tS.......GD...K......P.............YITASELY...Q...N..LT...K...EQA...DYCISRMKKYQ........................DPK.........GREIMEA...YDYAEFTQSLF-v......................................
A0A182FRR1_ANOAL/827-893 ...............DTDTAEQVIDSFRIL..A.......SD...K......P.............YILPDELR...R...E..LP...P...DQA...EYCIQRMPPYK........................GPN.........--AIPGA...LDYMSFSTALYG.......................................
A0A2G5TG06_9PELO/584-650 ...............DQDTVEQMIDSFRIL..A.......SG...K......T.............FITAEELE...R...E..LP...R...DQA...AYCMARMAPSR........................EPG.........--APPRS...FDYVTFSRSLY-s......................................
A0A1U8D3B9_MESAU/590-656 ...............DTDTADQVMASFKIL..A.......GD...K......N.............YITADELR...R...E..LP...P...DQA...EYCIARMAPYS........................GPD.........--SVPGA...LDYMSFSTALYG.......................................
A0A0L1HLB4_9PLEO/521-592 ...............DQNTAEQVFESFKEV..A.......DG...K......P.............YVTELDLR...H...S..LV...P...DEV..iDDLIATMPEHK........................GPDm.......qEDREIPK...FDYITYMQRYMG.......................................
ACTN4_HUMAN/841-907 ...............DTDTADQVIASFKVL..A.......GD...K......N.............FITAEELR...R...E..LP...P...DQA...EYCIARMAPYQ........................GPD.........--AVPGA...LDYKSFSTALYG.......................................
A0A284RFX7_9AGAR/559-625 ...............DQTSPEQLREAFRGI..A.......SD...K......L.............FVTELDLR...I...A..HL...P...ASS..vDYLKEVMPIVR........................---.........NDAGEPE...YDYERWLDDVFA.......................................
A0A0V1PGG1_9BILA/847-913 ...............DMDSSEQVIESFRVL..A.......NG...K......P.............FITAEELR...H...E..LP...P...DQA...EYCVQKMPAYR........................GPG.........--APPGS...FDYVSFSHQLYG.......................................
A0A1Y2D9X0_9BASI/682-761 ............erp---TGDKVRSCFRST..A.......GG...K......P.............YITELDLR...R...L..DL...P...ASA..iKFLLERLDFYEpqvvg..............edgalDVA.........EEDQEGA...RDYEAFLRMFM-e......................................
G1NH44_MELGA/627-693 ...............DTDTADQVMASFKIL..A.......GD...K......N.............YITVDELR...R...E..LP...P...DQA...EYCIARMAPYN........................GRD.........--AVPGA...LDYMSFSTALYG.......................................
A0A1V9X8Y5_9ACAR/928-991 ..............e-LDTAEQTIDSFRIL..A.......SD...K......P.............YITADELR...R...E..LP...P...DQA...EYCIRRMKPYP........................G--.........---APGG...LDYRSFSTMLYG.......................................
A0A074WHJ4_9PEZI/556-627 ...............DQYTAEQVFESFREV..A.......DG...K......P.............YVTELDLR...H...S..LI...P...DEL..iEDLVRTMPQHN........................GPDl.......qEDRDLEK...YDYITFMQKYMG.......................................
A0A194VM43_9PEZI/555-626 ...............DQNTAEQVFQSFREV..A.......DG...K......P.............YVTEMDLR...H...S..LV...P...DEV..iEQLIEIIPPHS........................GPDm.......kDDRGQPQ...YDYIAFMEKL--is.....................................
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G3UBG5_LOXAF/2408-2477 ...............NVKSSEEIESAFRAL.sS.......EG...K......P.............YVTKEELY...Q...N..LT...R...EQA...DYCVSHMKPYV........................DSK.........GRELPTA...FDYIEFTRSLF-v......................................
A0A0D2II07_9EURO/569-640 ...............DQNSAEQVFQSFREV..A.......DG...K......P.............YVTEMDLR...H...S..LI...P...DDL..iEDLLQSMPEHT........................GPDm.......eADRDVPK...YDYITFMQGM--ig.....................................
F7I2C3_CALJA/817-883 ...............DTDTADQVMASFKIL..A.......GD...K......N.............YITVEELR...R...E..LP...P...DQA...EYCIARMAPYT........................GPD.........--SVPGA...LDYMSFSTALYG.......................................
A0A182N7R8_9DIPT/2343-2416 ...............NVQSFEEIENAFRAI.tA.......SDprpR......P.............YVTKEELY...S...N..LT...K...DMA...DYCVQRMKPYN........................DPK........tGHPVTGA...LDYVEFTRTLFQ.......................................
J9EE33_WUCBA/6-51 ...........lnil---------------..-.......--...-......-.............--------...S...N..LT...P...EQA...EYCIKRMKPYT........................DAI........sGRSMPGA...LDYEQFVHTLFQ.......................................
A0A2C5YUV8_9HYPO/713-784 ...............DQNTAEQVFQSFREV..A.......DG...K......P.............YVTEMDLR...H...S..LV...P...DEV..iDRLVEMMPPHS........................GPDm.......aSDRGRAQ...YDYISFMEKM--in.....................................
G3TMT0_LOXAF/829-895 ...............ETDTAEQVVASFKIL..A.......GD...K......S.............YITAEELR...R...E..LP...A...EQA...EYCIRRMAPYK........................GTG.........--APVGA...LDYVAFSSALYG.......................................
A0A2K5NNI8_CERAT/831-897 ...............ETDTAEQVVASFKIL..A.......GD...K......N.............YITPEELR...R...E..LP...A...EQA...EYCIRRMVPYK........................GSG.........--APAGA...LDYVAFSSALYG.......................................
G7NW99_MACFA/2375-2443 ...............NIKSSNEIENAFQAL..A.......EG...K......S.............YITKEDMK...Q...A..LT...P...EQV...SFCATHMQQYM........................DPQ.........GRSHLSG...YDYAGFTNSYFG.......................................
A0A2K5HU47_COLAP/2253-2322 ...............NVKSSEEIESAFRAL.sS.......EG...K......P.............YVTKEELY...Q...N..LT...R...EQA...DYCVSHMKPYV........................DGK.........GRELPTA...FDYVEFTRSLF-v......................................
A0A1S9DBF0_ASPOZ/559-630 ...............DQNTAEQVLQSFREV..A.......DG...K......P.............YVTELDLR...H...S..LI...P...DEV..iDHLVQTMPRHE........................VFDr.......gEDQNEPK...YDYYSFMQKMME.......................................
A0A0D1ZHZ2_9EURO/569-640 ...............DQNSAEQVFQSFREV..A.......DG...K......P.............YVTEMDLR...H...S..LI...P...DDL..iEDLLQSMPEHT........................GPDm.......eADRDVPK...YDYITFMQGM--ig.....................................
B2VU57_PYRTR/554-625 ...............DQNTAEQVFESFKEV..A.......DG...K......P.............YVTELDLR...H...S..LV...P...DEV..iEDLLSTMPEHQ........................GPDm.......qEDRDLPK...FDYITYMQRYMG.......................................
A0A066XQ25_COLSU/723-794 ...............DQNTAEQVFQSFREV..A.......DG...K......P.............YVTEMDLR...H...S..LV...P...DEV..iDKLIEIIPQHN........................GPDt.......aEDRGMPQ...YDYIAFMEKL--is.....................................
A0A1S3SYH2_SALSA/832-898 ...............DTDTADQVIASFKIL..A.......AD...K......N.............FITAEELR...R...E..LP...P...DQA...EYCIARMAPYS........................GPD.........--AKPGA...LDYMSFSTALYG.......................................
A0A0K0D413_ANGCA/247-317 ...............NIQSSEEIEMAFRAL.sK.......EF...R......P.............YVTAEELY...A...N..LT...T...EQA...EYCIKRMKPYT........................DAI........sGRSIQGG...LDYEQFVHALFQ.......................................
A0A2I4CSR1_9TELE/2409-2478 ...............NVKSSEEIESAFRAL.sT.......EN...K......P.............YVTKEELY...Q...N..LT...K...EQA...DYCLSHMKPFL........................DSK.........GREVPSA...FDFVEFTRSLF-v......................................
F6UQC4_HORSE/2414-2483 ...............NVKSSEEIESAFRAL.sS.......EG...K......P.............YVTKEELY...Q...N..LT...R...EQA...DYCVSHMKPYV........................DSK.........GRELPTA...FDYVEFTRSLF-v......................................
A0A2A2KWK7_9BILA/799-865 ...............DNDTVEQMIDSFKIL..A.......SG...K......P.............FITAEEIR...R...E..LP...S...EQA...AYCMARMAPSN........................DPS.........--APHGA...FDYVTFSRTLYG.......................................
A0A1U8CY20_MESAU/2402-2471 ...............NVKSSEEIESAFRAL.sS.......EG...K......P.............YVTKEELY...Q...N..LT...R...EQA...DYCVSHMKPYV........................DGK.........GRELPTA...FDYVEFTRSLF-v......................................
W5KA22_ASTMX/52-118 ..............e-MDTAEQVAASFRIL..A.......AD...K......P.............YILIEELR...R...E..LP...P...EQA...EYCISRMPLYA........................GPD.........--GVPGA...LDYSAFSTALYG.......................................
SPTN1_MOUSE/2402-2471 ...............NVKSSEEIESAFRAL.sS.......EG...K......P.............YVTKEELY...Q...N..LT...R...EQA...DYCVSHMKPYV........................DGK.........GRELPTA...FDYVEFTRSLF-v......................................
E2R5T9_CANLF/841-907 ...............DTDTADQVIASFKVL..A.......GD...K......N.............FITAEELR...R...E..LP...P...DQA...EYCIARMAPYQ........................GPD.........--AVPGA...LDYKSFSTALYG.......................................
A0A183QNP8_9TREM/391-458 ..............g-ADTVEQMVNSFRTL..A.......GD...T......P.............YITTEQLK...R...E..LE...P...ELA...DYCINRMKAYN........................GSG.........-VANGGA...LDYTSFAASLYG.......................................
W4Y7J3_STRPU/2314-2383 ...............NVQSKDEIENAFRAL.sA.......EG...K......P.............YVTKQELY...A...N..LQ...T...DLA...EYCILRMEPYR........................DAK.........GREVPHA...LDYGKFTNNMFQ.......................................
#=GC SS_cons ...............CSSTHHHHHHHHHHH..C.......TS...S......S.............SEEHHHHH...H...H..ST...C...CHH...HHHHCCSEEE-........................SST.........--S-TTE...EECHHHHCCCTT.......................................
#=GC seq_cons ...............DscTuEQlhsSFRhL..A.......ss...K......P.............YlTt-ELR...+...p..Ls...P...-QA...-YClp+MsPYp........................usc...........sssuA...hDYhuFopuLat.......................................
//
