GenomeNet

Database: Pfam
Entry: ESR1_C
LinkDB: ESR1_C
Original site: ESR1_C 
#=GF ID   ESR1_C
#=GF AC   PF12743.8
#=GF DE   Oestrogen-type nuclear receptor final C-terminal 
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Willis S
#=GF GA   22.30 22.30;
#=GF TC   23.10 45.40;
#=GF NC   22.00 22.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Estrogen_receptor
#=GF RN   [1]
#=GF RM   10751636
#=GF RT   Estrogen receptor interaction with co-activators and
#=GF RT   co-repressors.
#=GF RA   Klinge CM;
#=GF RL   Steroids. 2000;65:227-251.
#=GF RN   [2]
#=GF RM   15196329
#=GF RT   Estrogen receptor-dependent activation of AP-1 via non-genomic
#=GF RT   signalling.
#=GF RA   Bjornstrom L, Sjoberg M;
#=GF RL   Nucl Recept. 2004;2:3.
#=GF DR   INTERPRO; IPR024736;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is the very C-terminal region of a subfamily of nuclear
#=GF CC   receptors that includes oestrogen receptors and other subfamily
#=GF CC   3 group A members. The actual function of this region is not
#=GF CC   known, but the domain is absent from all the other types of
#=GF CC   nuclear receptors. Oestrogen receptors modulate AP-1-dependent
#=GF CC   transcription [1] through two distinct mechanisms: via
#=GF CC   protein-protein interactions on DNA; and via non-genomic
#=GF CC   actions. The mechanism used depends on the cellular localisation
#=GF CC   of the receptor. In addition to the more extensively studied
#=GF CC   cross-talk on DNA, additional non-genomic actions might be very
#=GF CC   important in target tissues in which membrane-associated ERs are
#=GF CC   found. These non-genomic actions probably contribute to the
#=GF CC   overall physiological responses mediated by ligand-bound ERs [2]
#=GF CC   and might possibly be mediated via this C-terminal domain.
#=GF SQ   141
#=GS A0A091G8M1_9AVES/545-588  AC A0A091G8M1.1
#=GS A0A340XBK0_LIPVE/552-595  AC A0A340XBK0.1
#=GS G1SML6_RABIT/555-598      AC G1SML6.1
#=GS F7FPN2_CALJA/552-595      AC F7FPN2.2
#=GS G1PPH0_MYOLU/508-551      AC G1PPH0.1
#=GS A0A2I3TH38_PANTR/291-334  AC A0A2I3TH38.1
#=GS A0A2Y9M1Z4_DELLE/552-595  AC A0A2Y9M1Z4.1
#=GS ESR1_TAEGU/544-587        AC Q91250.1
#=GS A0A2U4CPV3_TURTR/552-595  AC A0A2U4CPV3.1
#=GS G1NJ86_MELGA/546-589      AC G1NJ86.1
#=GS A0A1S3G0Y9_DIPOR/565-608  AC A0A1S3G0Y9.1
#=GS A0A1S3G1D4_DIPOR/563-606  AC A0A1S3G1D4.1
#=GS A0A226PW99_COLVI/585-628  AC A0A226PW99.1
#=GS F6UQ47_HORSE/552-595      AC F6UQ47.2
#=GS A0A2I3GGQ0_NOMLE/291-334  AC A0A2I3GGQ0.1
#=GS A0A452J4X0_9SAUR/546-588  AC A0A452J4X0.1
#=GS B6CK19_PAPAN/552-595      AC B6CK19.1
#=GS F7CHI9_MONDO/547-589      AC F7CHI9.1
#=GS F1MX59_BOVIN/553-596      AC F1MX59.2
#=GS M3YGE7_MUSPF/552-597      AC M3YGE7.1
#=GS ESR1_HUMAN/552-595        AC P03372.2
#=GS ESR1_HUMAN/552-595        DR PDB; 5N10 C; 584-595;
#=GS A0A2K6GAR4_PROCO/552-599  AC A0A2K6GAR4.1
#=GS K7F8W0_PELSI/547-588      AC K7F8W0.1
#=GS R0JKI0_ANAPL/546-589      AC R0JKI0.1
#=GS D0FYH4_RAT/557-600        AC D0FYH4.1
#=GS A0A2K6C4L5_MACNE/552-595  AC A0A2K6C4L5.1
#=GS A0A1S2Z9V7_ERIEU/559-601  AC A0A1S2Z9V7.1
#=GS ESR1_MOUSE/556-599        AC P19785.1
#=GS Q6W5G7_XENLA/543-585      AC Q6W5G7.1
#=GS A0A091DLG8_FUKDA/399-442  AC A0A091DLG8.1
#=GS G3WR97_SARHA/546-588      AC G3WR97.1
#=GS A0A0G2JZG2_RAT/575-618    AC A0A0G2JZG2.1
#=GS A0A2U3XWW9_LEPWE/496-539  AC A0A2U3XWW9.1
#=GS A0A2I0MUF2_COLLI/466-509  AC A0A2I0MUF2.1
#=GS A0A2K5LGU3_CERAT/552-595  AC A0A2K5LGU3.1
#=GS B6CK15_PANPA/552-595      AC B6CK15.1
#=GS ESR1_BOVIN/553-596        AC P49884.3
#=GS A0A091I716_CALAN/545-588  AC A0A091I716.1
#=GS G3GU19_CRIGR/157-200      AC G3GU19.1
#=GS A0A1U7RVZ7_ALLSI/546-587  AC A0A1U7RVZ7.1
#=GS A0A1U8DE24_ALLSI/578-619  AC A0A1U8DE24.1
#=GS F6QUN5_MACMU/552-595      AC F6QUN5.1
#=GS F7E7S3_ORNAN/300-341      AC F7E7S3.1
#=GS A0A087R654_APTFO/546-589  AC A0A087R654.1
#=GS ESR1_HORSE/551-594        AC Q9TV98.1
#=GS A0A452C5D7_BALAS/385-422  AC A0A452C5D7.1
#=GS W5NZG7_SHEEP/452-495      AC W5NZG7.1
#=GS A0A2K5RE84_CEBCA/552-595  AC A0A2K5RE84.1
#=GS A0A2K5K536_COLAP/291-334  AC A0A2K5K536.1
#=GS A0A099ZAJ2_TINGU/546-588  AC A0A099ZAJ2.1
#=GS ESR1_MESAU/552-595        AC Q9QZJ5.1
#=GS ESR1_FELCA/552-595        AC Q53AD2.1
#=GS A0A2I3NDU8_PAPAN/291-334  AC A0A2I3NDU8.1
#=GS E5L8C9_CHICK/546-589      AC E5L8C9.1
#=GS A0A452EJX7_CAPHI/553-596  AC A0A452EJX7.1
#=GS G3R2K1_GORGO/552-595      AC G3R2K1.1
#=GS A0A384CEI2_URSMA/429-472  AC A0A384CEI2.1
#=GS A0A0Q3PGC6_AMAAE/543-584  AC A0A0Q3PGC6.1
#=GS A0A2K5X1A2_MACFA/291-334  AC A0A2K5X1A2.1
#=GS ESR1_PIG/552-595          AC Q29040.1
#=GS Q25C14_XENTR/543-585      AC Q25C14.1
#=GS A0A2Y9D6T5_TRIMA/552-595  AC A0A2Y9D6T5.1
#=GS ESR1_ANOCA/306-348        AC Q9YHT3.2
#=GS A0A1S2Z9U9_ERIEU/561-603  AC A0A1S2Z9U9.1
#=GS A0A2K5LGR6_CERAT/291-334  AC A0A2K5LGR6.1
#=GS A0A2K5EHI0_AOTNA/291-334  AC A0A2K5EHI0.1
#=GS A0A3Q0EBQ7_TARSY/553-596  AC A0A3Q0EBQ7.1
#=GS H9GB48_ANOCA/599-641      AC H9GB48.2
#=GS L9LCV6_TUPCH/63-106       AC L9LCV6.1
#=GS A0A093PJD1_9PASS/546-589  AC A0A093PJD1.1
#=GS A0A2Y9L592_ENHLU/552-597  AC A0A2Y9L592.1
#=GS A0A0A0AF31_CHAVO/546-589  AC A0A0A0AF31.1
#=GS A0A2I0MUE3_COLLI/578-621  AC A0A2I0MUE3.1
#=GS A0A455BS19_PHYMC/513-556  AC A0A455BS19.1
#=GS A0A455BNS6_PHYMC/552-595  AC A0A455BNS6.1
#=GS A0A2K5K518_COLAP/552-595  AC A0A2K5K518.1
#=GS A0A091JHK4_EGRGA/299-342  AC A0A091JHK4.1
#=GS I3M8I7_ICTTR/550-593      AC I3M8I7.2
#=GS A0A0G2JXN1_RAT/1-41       AC A0A0G2JXN1.1
#=GS A0A1A6GVU5_NEOLE/103-146  AC A0A1A6GVU5.1
#=GS A0A2K6C4N1_MACNE/291-334  AC A0A2K6C4N1.1
#=GS K0I5S7_COLLI/544-587      AC K0I5S7.1
#=GS A0A2J8Q9X9_PANTR/552-595  AC A0A2J8Q9X9.1
#=GS A0A1U7Q202_MESAU/552-595  AC A0A1U7Q202.1
#=GS A0A0D9RP33_CHLSB/444-487  AC A0A0D9RP33.1
#=GS A0A3M0KNU9_HIRRU/461-504  AC A0A3M0KNU9.1
#=GS U3KCX4_FICAL/546-589      AC U3KCX4.1
#=GS A0A3Q0GNM7_ALLSI/586-627  AC A0A3Q0GNM7.1
#=GS G3TES0_LOXAF/189-232      AC G3TES0.1
#=GS A0A0G2K0D4_RAT/589-632    AC A0A0G2K0D4.1
#=GS A0A402FFH3_9SAUR/133-175  AC A0A402FFH3.1
#=GS A0A3Q2UHY1_CHICK/608-651  AC A0A3Q2UHY1.1
#=GS A0A1S2Z9W4_ERIEU/558-600  AC A0A1S2Z9W4.1
#=GS A0A218V748_9PASE/578-621  AC A0A218V748.1
#=GS Q9H2M1_HUMAN/291-334      AC Q9H2M1.1
#=GS A0A093JH47_STRCA/546-589  AC A0A093JH47.1
#=GS A0A2U3ZJE7_ODORO/554-597  AC A0A2U3ZJE7.1
#=GS A0A093G6I6_DRYPU/546-589  AC A0A093G6I6.1
#=GS G1LX33_AILME/406-449      AC G1LX33.1
#=GS A0A1U8D273_MESAU/597-640  AC A0A1U8D273.1
#=GS A0A2U3W7F4_ODORO/552-595  AC A0A2U3W7F4.1
#=GS F6QUR4_MACMU/291-334      AC F6QUR4.1
#=GS A0A2U3ZJE3_ODORO/551-594  AC A0A2U3ZJE3.1
#=GS A0A091EZL1_CORBR/546-589  AC A0A091EZL1.1
#=GS A0A2K6JSN0_RHIBE/291-334  AC A0A2K6JSN0.1
#=GS A0A4D9EP83_9SAUR/575-617  AC A0A4D9EP83.1
#=GS ESR1_CHICK/546-589        AC P06212.1
#=GS A0A2K5ZVV2_MANLE/291-334  AC A0A2K5ZVV2.1
#=GS A0A2K5REA1_CEBCA/291-334  AC A0A2K5REA1.1
#=GS A0A091V5E3_NIPNI/546-589  AC A0A091V5E3.1
#=GS F6U1C9_HORSE/565-608      AC F6U1C9.2
#=GS U3IA61_ANAPP/505-548      AC U3IA61.2
#=GS F7DPT5_CALJA/291-334      AC F7DPT5.2
#=GS H0X794_OTOGA/555-598      AC H0X794.1
#=GS A0A151NLK8_ALLMI/586-627  AC A0A151NLK8.1
#=GS F6V0I8_CANLF/553-596      AC F6V0I8.1
#=GS A0A2K6JSL4_RHIBE/552-595  AC A0A2K6JSL4.1
#=GS A0A2I2Y573_GORGO/291-334  AC A0A2I2Y573.1
#=GS G7P4Y2_MACFA/552-595      AC G7P4Y2.1
#=GS L5KFQ3_PTEAL/583-625      AC L5KFQ3.1
#=GS A0A1V4JLJ4_PATFA/544-587  AC A0A1V4JLJ4.1
#=GS U3KCX9_FICAL/544-587      AC U3KCX9.1
#=GS A0A3Q0GT86_ALLSI/585-626  AC A0A3Q0GT86.1
#=GS A0A2K5EHF1_AOTNA/552-595  AC A0A2K5EHF1.1
#=GS A0A3Q7X2Q2_URSAR/552-595  AC A0A3Q7X2Q2.1
#=GS H0VC28_CAVPO/554-596      AC H0VC28.1
#=GS G1RZN0_NOMLE/552-595      AC G1RZN0.1
#=GS A0A2I0MUE0_COLLI/577-620  AC A0A2I0MUE0.1
#=GS A0A091W4K7_OPIHO/546-589  AC A0A091W4K7.1
#=GS A0A3Q7TEZ7_VULVU/552-595  AC A0A3Q7TEZ7.1
#=GS A0A1L8G265_XENLA/543-585  AC A0A1L8G265.1
#=GS A0A2K6GAN3_PROCO/291-338  AC A0A2K6GAN3.1
#=GS ESR1_RAT/557-600          AC P06211.1
#=GS A0A3Q0E805_TARSY/479-522  AC A0A3Q0E805.1
#=GS A0A2U4CPV0_TURTR/554-597  AC A0A2U4CPV0.1
#=GS A0A2J8XAF0_PONAB/552-595  AC A0A2J8XAF0.1
#=GS A0A2Y9KRJ1_ENHLU/551-596  AC A0A2Y9KRJ1.1
#=GS M3X1F5_FELCA/552-595      AC M3X1F5.3
#=GS A0A2K5ZVU6_MANLE/552-595  AC A0A2K5ZVU6.1
#=GS H0ZLY1_TAEGU/546-589      AC H0ZLY1.1
#=GS A0A2Y9KSC8_ENHLU/554-599  AC A0A2Y9KSC8.1
A0A091G8M1_9AVES/545-588             .....PAAR..SA.APMEQENRSQLTTA-SASSHSLQSFY...InSKEEDNMQNTI....
A0A340XBK0_LIPVE/552-595             .....PANF..GS.APTEDVNQSQLATAGSTSSHSLQTYY...I.TGEAENFPTTV....
G1SML6_RABIT/555-598                 .....PANR..GG.VPMEEPAQGQLTTTSAASAHSLQTYY...I.PGEAEDFPSTI....
F7FPN2_CALJA/552-595                 .....PTNR..AG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGEAESFPTTI....
G1PPH0_MYOLU/508-551                 .....PASR..GA.APMEEPHQGQMATTGPTLPHSLPTYY...I.SGEAEGFPNTV....
A0A2I3TH38_PANTR/291-334             .....PTSR..GG.APVEETDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPATV....
A0A2Y9M1Z4_DELLE/552-595             .....PANF..GS.APTEDVNQSQLATAGSTSSHSLQTYY...I.TGEAENFPTTV....
ESR1_TAEGU/544-587                   .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTL....
A0A2U4CPV3_TURTR/552-595             .....PANF..GS.APPEDVSQSQLATAGSTSSHSLQTYY...I.TGEAENFPTTI....
G1NJ86_MELGA/546-589                 .....PAAR..SA.APMEEENQSQLTTA-PASSHSLQSFY...InSKEEESMQNTI....
A0A1S3G0Y9_DIPOR/565-608             .....PASR..QG.VAPEEPMQSQLTANGSASAHSLQTYY...I.SQEAESFSNT-m...
A0A1S3G1D4_DIPOR/563-606             .....PASR..QG.VAPEEPMQSQLTANGSASAHSLQTYY...I.SQEAESFSNT-m...
A0A226PW99_COLVI/585-628             .....PAAR..SA.APMEEENRSQLTTA-PASSHSLQSFY...IdSKEEESMQNTI....
F6UQ47_HORSE/552-595                 .....PANH..GG.APMEETNQSQLATTGSTSPHSMQTYY...I.TGEAEGFPNTI....
A0A2I3GGQ0_NOMLE/291-334             .....PASR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPATV....
A0A452J4X0_9SAUR/546-588             .....PATK..NA.PQMEEENRSQLTTA-STSSHSLQSFY...V.NREDENLQNTV....
B6CK19_PAPAN/552-595                 .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
F7CHI9_MONDO/547-589                 .....PGNR..GS.APRDEDNQNQLATA-STSSHSLQTYY...I.TRDEESFPTTI....
F1MX59_BOVIN/553-596                 .....PANF..GS.APPEDVNQSQLAPTGCTSSHSLQTYY...I.TGEAENFPSTV....
M3YGE7_MUSPF/552-597                 .....PAGRggGS.APMEEMSESQLATTGATSSHSLQAYY...I.TEEAASFPSTV....
ESR1_HUMAN/552-595                   .....PTSR..GG.ASVEETDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPATV....
#=GR ESR1_HUMAN/552-595        SS    .....XXXX..XX.XXXXXXXXXXXXXXXXXXXXXXXXXX...G.GS-GGG-----....
A0A2K6GAR4_PROCO/552-599             ptgrp----..GG.APVEEANQGQLAALGSTSSHSLQKYYattT.TGEAESFPTTA....
K7F8W0_PELSI/547-588                 ...gs---R..NA.PHVEEENQSQLTTA-STSSHSLQPFY...V.SREDENLQTTI....
R0JKI0_ANAPL/546-589                 .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTI....
D0FYH4_RAT/557-600                   .....PASR..MG.VPPEEPSQSQLTTTSSTSAHSLQTYY...I.PPEAEGFPNTI....
A0A2K6C4L5_MACNE/552-595             .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
A0A1S2Z9V7_ERIEU/559-601             .....PANR..GAaATMEEMSQGPLATN-GQASHSLQTYY...I.TGEAENFPT--i...
ESR1_MOUSE/556-599                   .....PASR..MG.VPPEEPSQTQLATTSSTSAHSLQTYY...I.PPEAEGFPNTI....
Q6W5G7_XENLA/543-585                 .....PKDK..TT.TQ-EEDSRSPPTTTVNGASPCLQPYY...T.NTEEVSLQSTV....
A0A091DLG8_FUKDA/399-442             .....PSDP..MG.GSPEEPSQSQLATMGSSSAHSLQTYY...V.PQEAEGFPNTV....
G3WR97_SARHA/546-588                 .....PGNR..GG.APMEEDNQNQLATA-STSSHSLQTYY...I.TRDEESFPTTI....
A0A0G2JZG2_RAT/575-618               .....PASR..MG.VPPEEPSQSQLTTTSSTSAHSLQTYY...I.PPEAEGFPNTI....
A0A2U3XWW9_LEPWE/496-539             .....PASR..GG.APVEEMNQSQLATTGSTSSHSLQAYY...I.TEESGSFPTTV....
A0A2I0MUF2_COLLI/466-509             .....PAAR..SA.APTEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTI....
A0A2K5LGU3_CERAT/552-595             .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
B6CK15_PANPA/552-595                 .....PTSR..GG.APVEETDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPATV....
ESR1_BOVIN/553-596                   .....PANF..GS.APPEDVNQSQLAPTGCTSSHSLQTYY...I.TGEAENFPSTV....
A0A091I716_CALAN/545-588             .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...InGKEEENMQNTV....
G3GU19_CRIGR/157-200                 .....PASR..MG.VSPEEPSQSQLTTTSSTSSHSLQTYY...I.PPEAESFPNTI....
A0A1U7RVZ7_ALLSI/546-587             .....PAAR..NA.AQVEEETR--LTTA-SASSHSLQSFY...InNREDENLQNTI....
A0A1U8DE24_ALLSI/578-619             .....PAAR..NA.AQVEEETR--LTTA-SASSHSLQSFY...InNREDENLQNTI....
F6QUN5_MACMU/552-595                 .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
F7E7S3_ORNAN/300-341                 ...pg---R..SN.APMEEETQNQLATA-STSSHSLQSYY...I.TREDENFPTTI....
A0A087R654_APTFO/546-589             .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...InSKEEETMQNTI....
ESR1_HORSE/551-594                   .....PANH..GG.APMEETNQSQLATTGSTSPHSMQTYY...I.TGEAEGFPNTI....
A0A452C5D7_BALAS/385-422             .rthg----..--.----DVNQSQLATAGSTSSHSLQTYY...I.TGEAENFPTTV....
W5NZG7_SHEEP/452-495                 .....PANF..GS.TPPEDVNQSQLATTGCTSSHSLQTYY...I.TGEAENFPSTV....
A0A2K5RE84_CEBCA/552-595             .....PTNR..TG.APMEETDQSHLATASSTSSHSLQKYY...I.TGETEGFPTTI....
A0A2K5K536_COLAP/291-334             .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
A0A099ZAJ2_TINGU/546-588             .....PAAR..SA.APMEEENRSQLTAS-SASSHSLQAFY...M.SNREENMQNTI....
ESR1_MESAU/552-595                   .....PVSR..MG.VSPEEPSQSQLTTTNSTSSHSLQTYY...I.PSEAESFPNTI....
ESR1_FELCA/552-595                   .....PANR..GG.APMEEMNQSQLATTGSTSAHSLQAYY...I.TEEAGAFPTTV....
A0A2I3NDU8_PAPAN/291-334             .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
E5L8C9_CHICK/546-589                 .....PAAR..SA.APMEEENRNQLTTA-PASSHSLQSFY...InSKEEESMQNTI....
A0A452EJX7_CAPHI/553-596             .....PANF..GS.TPPEDVNQSQLATTGCTSSHSLQTYY...I.TEEAENFPSTV....
G3R2K1_GORGO/552-595                 .....PTSR..GG.APVEETDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPATI....
A0A384CEI2_URSMA/429-472             .....PASR..GG.APVEEMNQSQLATTGSTSSHSLQAYY...I.TEEPGSFPTTV....
A0A0Q3PGC6_AMAAE/543-584             .....PAAR..SA.APMEEENRSQLTTA-SASSHSMQPFY...I.GKEEEK-----vgee
A0A2K5X1A2_MACFA/291-334             .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
ESR1_PIG/552-595                     .....PTNL..GG.PPPEDMSQSQLATSGSTPSHSLQMYY...I.TGEAENFPTTI....
Q25C14_XENTR/543-585                 .....PKDK..AT.AQ-EEDSRSPLTTTANGASPCLQPFY...T.STEEVSLQSTV....
A0A2Y9D6T5_TRIMA/552-595             .....PANH..GG.TPMEETSQNQLATMGSTSSHSLQTYY...I.TGEAESLPTTL....
ESR1_ANOCA/306-348                   .....PAAK..GS.PPSEDDPLNQLAVP-SPSMHSLLPCY...V.NKQEEGNEQE-a...
A0A1S2Z9U9_ERIEU/561-603             .....PANR..GAaATMEEMSQGPLATN-GQASHSLQTYY...I.TGEAENFPT--i...
A0A2K5LGR6_CERAT/291-334             .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
A0A2K5EHI0_AOTNA/291-334             .....PTNR..AG.APMEEMDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPTTI....
A0A3Q0EBQ7_TARSY/553-596             .....PTDH..GG.APMEEMDQSQLATMGPTSSHSLQKYY...I.TGEVEGFPPTI....
H9GB48_ANOCA/599-641                 .....PAAK..GS.PPSEDDPLNQLAVP-SPSMHSLLPCY...V.NKQEEGNEQE-a...
L9LCV6_TUPCH/63-106                  .....PAGR..AG.VPMEEMNQSQLTTTGSTSSHSLQTYY...I.TGEAESFPTTL....
A0A093PJD1_9PASS/546-589             .....PTAR..SA.APVEEENQSQLTTA-SASSHSLQSFY...VnSKEEENMQNTI....
A0A2Y9L592_ENHLU/552-597             .....PAGRggGS.APMEEMSESQLATTGATSSHSLQAYY...I.TEEPGSFPTTV....
A0A0A0AF31_CHAVO/546-589             .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTI....
A0A2I0MUE3_COLLI/578-621             .....PAAR..SA.APTEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTI....
A0A455BS19_PHYMC/513-556             .....PANF..GS.APTEDVNQSRLATAGSTSSHSLQTYY...I.TGEAENFPTTV....
A0A455BNS6_PHYMC/552-595             .....PANF..GS.APTEDVNQSRLATAGSTSSHSLQTYY...I.TGEAENFPTTV....
A0A2K5K518_COLAP/552-595             .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
A0A091JHK4_EGRGA/299-342             .....PGAR..SA.APVEEENRSQLTTA-SASSHSLQSFY...InSKEEETMQNTI....
I3M8I7_ICTTR/550-593                 .....PASR..GG.GSPEESSQSLLATTGSTSAHSLQTYY...I.PQEAEGFPNT-m...
A0A0G2JXN1_RAT/1-41                  .....---R..MG.VPPEEPSQSQLTTTSSTSAHSLQTYY...I.PPEAEGFPNTI....
A0A1A6GVU5_NEOLE/103-146             .....PASR..MG.VSPEEPSQSQLTTTSSTSAHSLQTYY...I.PPETEGFPNTI....
A0A2K6C4N1_MACNE/291-334             .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
K0I5S7_COLLI/544-587                 .....PAAR..SA.APTEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTI....
A0A2J8Q9X9_PANTR/552-595             .....PTSR..GG.APVEETDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPATV....
A0A1U7Q202_MESAU/552-595             .....PVSR..MG.VSPEEPSQSQLTTTNSTSSHSLQTYY...I.PSEAESFPNTI....
A0A0D9RP33_CHLSB/444-487             .....PASR..GG.APMEETDQSRLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
A0A3M0KNU9_HIRRU/461-504             .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...VnSKEEENMQNTI....
U3KCX4_FICAL/546-589                 .....PAAR..SA.APMEEENRGQLTTA-SAASHSLQSFY...VnSKEEENMQSTI....
A0A3Q0GNM7_ALLSI/586-627             .....PAAR..NA.AQVEEETR--LTTA-SASSHSLQSFY...InNREDENLQNTI....
G3TES0_LOXAF/189-232                 .....PTNR..GG.APMEETNQNQLATMGSTSSHSMQPYY...I.TGEAESLPTTL....
A0A0G2K0D4_RAT/589-632               .....PASR..MG.VPPEEPSQSQLTTTSSTSAHSLQTYY...I.PPEAEGFPNTI....
A0A402FFH3_9SAUR/133-175             .....-ATR..ST.PQGEEEPMNQLATT-STSTHSLQPCY...V.NKMEDENEQ--qai.
A0A3Q2UHY1_CHICK/608-651             .....PAAR..SA.APMEEENRNQLTTA-PASSHSLQSFY...InSKEEESMQNTI....
A0A1S2Z9W4_ERIEU/558-600             .....PANR..GAaATMEEMSQGPLATN-GQASHSLQTYY...I.TGEAENFPT--i...
A0A218V748_9PASE/578-621             .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTL....
Q9H2M1_HUMAN/291-334                 .....PTSR..GG.ASVEETDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPATV....
A0A093JH47_STRCA/546-589             .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...MnNREEENMQNTI....
A0A2U3ZJE7_ODORO/554-597             .....PASR..GG.APVEEMNQSQLATTGSTSSHSLQAYY...I.TEEAGSFPTTV....
A0A093G6I6_DRYPU/546-589             .....PAAR..SA.APMEEENRSQLTAA-SASSHTLQSFY...InSKEEENMQNAI....
G1LX33_AILME/406-449                 .....PASR..GG.APMEEMNQSQLATTGSTSSHSLQAYY...I.TEEPGSFPSTV....
A0A1U8D273_MESAU/597-640             .....PVSR..MG.VSPEEPSQSQLTTTNSTSSHSLQTYY...I.PSEAESFPNTI....
A0A2U3W7F4_ODORO/552-595             .....PASR..GG.APVEEMNQSQLATTGSTSSHSLQAYY...I.TEEAGSFPTTV....
F6QUR4_MACMU/291-334                 .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
A0A2U3ZJE3_ODORO/551-594             .....PASR..GG.APVEEMNQSQLATTGSTSSHSLQAYY...I.TEEAGSFPTTV....
A0A091EZL1_CORBR/546-589             .....PAAR..SA.EPMEEENRSQLTAA-SASSHSLQSFY...VnSKEEENTQNTI....
A0A2K6JSN0_RHIBE/291-334             .....PTSR..GG.APLEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
A0A4D9EP83_9SAUR/575-617             .....PAAK..NA.PQMEEENRSQLTTA-STSSHSLQTFY...V.NREDENLQNTV....
ESR1_CHICK/546-589                   .....PAAR..SA.APMEEENRNQLTTA-PASSHSLQSFY...InSKEEESMQNTI....
A0A2K5ZVV2_MANLE/291-334             .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
A0A2K5REA1_CEBCA/291-334             .....PTNR..TG.APMEETDQSHLATASSTSSHSLQKYY...I.TGETEGFPTTI....
A0A091V5E3_NIPNI/546-589             .....PASR..SA.APMEEENRSQLTTA-SASSHSLQSFY...InSKEEDNMQNTI....
F6U1C9_HORSE/565-608                 .....PANH..GG.APMEETNQSQLATTGSTSPHSMQTYY...I.TGEAEGFPNTI....
U3IA61_ANAPP/505-548                 .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTI....
F7DPT5_CALJA/291-334                 .....PTNR..AG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGEAESFPTTI....
H0X794_OTOGA/555-598                 .....PAAR..MG.VSPEEMGQSQLASTGSTSSHSLQKFY...I.TGEAESFPATI....
A0A151NLK8_ALLMI/586-627             .....PAAR..NA.AQVEEETR--LTTA-SASSHSLQSFY...InNREDENLQNTI....
F6V0I8_CANLF/553-596                 .....PASR..GG.VPMEETNQSQLATTGPTSSHSLQTYY...I.TEEAGNFPTTV....
A0A2K6JSL4_RHIBE/552-595             .....PTSR..GG.APLEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
A0A2I2Y573_GORGO/291-334             .....PTSR..GG.APVEETDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPATI....
G7P4Y2_MACFA/552-595                 .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
L5KFQ3_PTEAL/583-625                 .....-TNR..GD.TPMAETHQSHMAATAPTSSHSLQTYY...I.SGEAESFPSTI....
A0A1V4JLJ4_PATFA/544-587             .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTI....
U3KCX9_FICAL/544-587                 .....PAAR..SA.APMEEENRGQLTTA-SAASHSLQSFY...VnSKEEENMQSTI....
A0A3Q0GT86_ALLSI/585-626             .....PAAR..NA.AQVEEETR--LTTA-SASSHSLQSFY...InNREDENLQNTI....
A0A2K5EHF1_AOTNA/552-595             .....PTNR..AG.APMEEMDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPTTI....
A0A3Q7X2Q2_URSAR/552-595             .....PASR..GG.APVEEMNQSQLATTGSTSSHSLQAYY...I.TEEPGSFPTTV....
H0VC28_CAVPO/554-596                 ..snp----..MG.GSPEEPSQSQLATIGSSSAHSLQTYY...V.SQEAESFPNTI....
G1RZN0_NOMLE/552-595                 .....PASR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPATV....
A0A2I0MUE0_COLLI/577-620             .....PAAR..SA.APTEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTI....
A0A091W4K7_OPIHO/546-589             .....PPAR..SA.APMEEENRSQLTTA-PASSHSLQSFY...InSKEEENIQNTI....
A0A3Q7TEZ7_VULVU/552-595             .....PASR..GG.VPMEETNQSQLATTGPTSSHSLQMYY...I.TEEAGSFPTTV....
A0A1L8G265_XENLA/543-585             .....PKDK..TT.TQ-EEESRSPLSTTVNGASPCLQPFY...K.NTEEVGLQSTV....
A0A2K6GAN3_PROCO/291-338             ptgrp----..GG.APVEEANQGQLAALGSTSSHSLQKYYattT.TGEAESFPTTA....
ESR1_RAT/557-600                     .....PASR..MG.VPPEEPSQSQLTTTSSTSAHSLQTYY...I.PPEAEGFPNTI....
A0A3Q0E805_TARSY/479-522             .....PTDH..GG.APMEEMDQSQLATMGPTSSHSLQKYY...I.TGEVEGFPPTI....
A0A2U4CPV0_TURTR/554-597             .....PANF..GS.APPEDVSQSQLATAGSTSSHSLQTYY...I.TGEAENFPTTI....
A0A2J8XAF0_PONAB/552-595             .....PTSR..GG.APVEETDQSHLATAGSTSSHSLQKYY...I.TGEAEGFPATV....
A0A2Y9KRJ1_ENHLU/551-596             .....PAGRggGS.APMEEMSESQLATTGATSSHSLQAYY...I.TEEPGSFPTTV....
M3X1F5_FELCA/552-595                 .....PANR..GG.APMEEMNQSQLATTGSTSAHSLQAYY...I.TEEAGAFPTTV....
A0A2K5ZVU6_MANLE/552-595             .....PTSR..GG.APMEETDQSHLATAGSTSSHSLQKYY...I.TGDAEGFPATV....
H0ZLY1_TAEGU/546-589                 .....PAAR..SA.APMEEENRSQLTTA-SASSHSLQSFY...InSKEEENMQNTL....
A0A2Y9KSC8_ENHLU/554-599             .....PAGRggGS.APMEEMSESQLATTGATSSHSLQAYY...I.TEEPGSFPTTV....
#=GC SS_cons                         .....XXXX..XX.XXXXXXXXXXXXXXXXXXXXXXXXXX...G.GS-GGG-----....
#=GC seq_cons                        .....PAuR..uu.APhEEpsQSQLATsuSTSSHSLQsYY...I.otEsEuFPsTl....
//
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