GenomeNet

Database: Pfam
Entry: FERM_F2
LinkDB: FERM_F2
Original site: FERM_F2 
#=GF ID   FERM_F2
#=GF AC   PF18377.1
#=GF DE   FERM F2 acyl-CoA binding protein-like domain
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   ECOD:EUF05222
#=GF GA   26.00 26.00;
#=GF TC   26.40 26.80;
#=GF NC   25.90 25.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   FERM_domain
#=GF RN   [1]
#=GF RM   27725180
#=GF RT   Crystal Structure of a Complex of the Intracellular Domain of
#=GF RT   Interferon lambda Receptor 1 (IFNLR1) and the FERM/SH2 Domains
#=GF RT   of Human JAK1.
#=GF RA   Zhang D, Wlodawer A, Lubkowski J;
#=GF RL   J Mol Biol. 2016;428:4651-4668.
#=GF RN   [2]
#=GF RM   27227461
#=GF RT   Crystal Structure of the FERM-SH2 Module of Human Jak2.
#=GF RA   McNally R, Toms AV, Eck MJ;
#=GF RL   PLoS One. 2016;11:e0156218.
#=GF RN   [3]
#=GF RM   28458652
#=GF RT   The Janus Kinase (JAK) FERM and SH2 Domains: Bringing
#=GF RT   Specificity to JAK-Receptor Interactions.
#=GF RA   Ferrao R, Lupardus PJ;
#=GF RL   Front Endocrinol (Lausanne). 2017;8:71.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is an F2 lobe domain consisting of an acyl-CoA binding
#=GF CC   protein fold found in FERM region of Jak-family tyrosine kinases
#=GF CC   [1]. Multidomain JAK molecules interact with receptors through
#=GF CC   their FERM and SH2-like domains, triggering a series of
#=GF CC   phosphorylation events, resulting in the activation of their
#=GF CC   kinase domains [2].  Overall, the FERM region maintains the
#=GF CC   typical three-lobed architecture, with an F1 lobe consisting of
#=GF CC   a ubiquitin-like fold, an F2 lobe consisting of an acyl-CoA
#=GF CC   binding protein fold, and an F3 lobe consisting of a
#=GF CC   pleckstrin-homology (PH) fold. JAK1 FERM-F2 domain has been
#=GF CC   shown to act as the interaction site for the IFNLR1 box1 motif
#=GF CC   (PxxLxF) of class II cytokine receptors which is essential for
#=GF CC   kinase activation [3].
#=GF SQ   484
#=GS A0A1S3KKN4_SALSA/145-275  AC A0A1S3KKN4.1
#=GS H0VSL1_CAVPO/126-245      AC H0VSL1.2
#=GS A0A087YP74_POEFO/150-269  AC A0A087YP74.2
#=GS G3WQ34_SARHA/142-261      AC G3WQ34.1
#=GS H2V1W4_TAKRU/141-260      AC H2V1W4.1
#=GS A0A0P7UXN8_9TELE/143-273  AC A0A0P7UXN8.1
#=GS S9YP10_CAMFR/140-259      AC S9YP10.1
#=GS H2VE40_TAKRU/170-237      AC H2VE40.1
#=GS H0X6H8_OTOGA/142-261      AC H0X6H8.1
#=GS A0A099ZDF1_TINGU/141-260  AC A0A099ZDF1.1
#=GS A0A2K5L3K1_CERAT/113-232  AC A0A2K5L3K1.1
#=GS A0A0D9QZJ5_CHLSB/71-190   AC A0A0D9QZJ5.1
#=GS H0V2Z6_CAVPO/142-267      AC H0V2Z6.2
#=GS E2RG40_CANLF/126-245      AC E2RG40.2
#=GS H2TCV2_TAKRU/129-248      AC H2TCV2.1
#=GS A0A099YZG4_TINGU/147-286  AC A0A099YZG4.1
#=GS A0A0P7V4D3_9TELE/149-279  AC A0A0P7V4D3.1
#=GS G5B4Y4_HETGA/142-261      AC G5B4Y4.1
#=GS G5BSN6_HETGA/315-445      AC G5BSN6.1
#=GS A0A2I3T122_PANTR/126-245  AC A0A2I3T122.1
#=GS A0A0Q3QCQ8_AMAAE/138-268  AC A0A0Q3QCQ8.1
#=GS H2PZ66_PANTR/147-277      AC H2PZ66.1
#=GS H9H0M3_MELGA/1-114        AC H9H0M3.1
#=GS A0A0Q3U4V2_AMAAE/157-287  AC A0A0Q3U4V2.1
#=GS M3XFX5_FELCA/142-261      AC M3XFX5.2
#=GS A0A0Q3V9G8_AMAAE/139-258  AC A0A0Q3V9G8.1
#=GS A0A286XLG2_CAVPO/126-245  AC A0A286XLG2.1
#=GS A0A087R0W7_APTFO/147-277  AC A0A087R0W7.1
#=GS H2VE38_TAKRU/141-267      AC H2VE38.1
#=GS Q9TTJ1_PIG/135-265        AC Q9TTJ1.1
#=GS A0A093GIU2_DRYPU/141-260  AC A0A093GIU2.1
#=GS A0A226N5B7_CALSU/160-248  AC A0A226N5B7.1
#=GS W5LAY4_ASTMX/143-262      AC W5LAY4.1
#=GS F6QBA9_CALJA/77-202       AC F6QBA9.1
#=GS K7FHA5_PELSI/71-177       AC K7FHA5.1
#=GS B0V237_DANRE/127-246      AC B0V237.1
#=GS G7PSF3_MACFA/142-261      AC G7PSF3.1
#=GS A0A087VRZ8_BALRE/147-277  AC A0A087VRZ8.1
#=GS A0A2I0LKC6_COLLI/134-253  AC A0A2I0LKC6.1
#=GS A0A2K5L3H2_CERAT/126-245  AC A0A2K5L3H2.1
#=GS E2RPW6_CANLF/142-261      AC E2RPW6.2
#=GS E1BCP6_BOVIN/142-261      AC E1BCP6.1
#=GS A0A2I3RU79_PANTR/145-275  AC A0A2I3RU79.1
#=GS U3K7L6_FICAL/140-259      AC U3K7L6.1
#=GS A0A091DWB5_FUKDA/142-261  AC A0A091DWB5.1
#=GS A0A1B0GTR9_HUMAN/142-261  AC A0A1B0GTR9.1
#=GS W4ZL99_STRPU/114-214      AC W4ZL99.1
#=GS H2NY19_PONAB/125-244      AC H2NY19.2
#=GS G3V9W2_RAT/147-277        AC G3V9W2.1
#=GS G3U3K6_LOXAF/142-261      AC G3U3K6.1
#=GS TYK2_HUMAN/141-266        AC P29597.3
#=GS TYK2_HUMAN/141-266        DR PDB; 4PO6 A; 141-266;
#=GS A0A2K5NH39_CERAT/147-277  AC A0A2K5NH39.1
#=GS G1KCE0_ANOCA/140-259      AC G1KCE0.2
#=GS M7AKN2_CHEMY/458-588      AC M7AKN2.1
#=GS W5MVJ9_LEPOC/140-259      AC W5MVJ9.1
#=GS G3HY52_CRIGR/135-265      AC G3HY52.1
#=GS A0A1D5PTI3_CHICK/1-38     AC A0A1D5PTI3.1
#=GS A0A226MYM3_COLVI/26-128   AC A0A226MYM3.1
#=GS A0A091Q3A9_LEPDC/141-260  AC A0A091Q3A9.1
#=GS A0A091RTW2_9GRUI/141-260  AC A0A091RTW2.1
#=GS W5KTR4_ASTMX/149-279      AC W5KTR4.1
#=GS A0A151N0Y0_ALLMI/138-268  AC A0A151N0Y0.1
#=GS A0A1U8CMQ3_MESAU/140-259  AC A0A1U8CMQ3.1
#=GS A0A093H4Q9_STRCA/147-277  AC A0A093H4Q9.1
#=GS A0A091PZE8_LEPDC/147-277  AC A0A091PZE8.1
#=GS W5PZ17_SHEEP/126-223      AC W5PZ17.1
#=GS JAK2_RAT/142-261          AC Q62689.1
#=GS A0A096P1L9_PAPAN/142-261  AC A0A096P1L9.2
#=GS A0A226PM45_COLVI/170-289  AC A0A226PM45.1
#=GS A0A226MI72_COLVI/130-249  AC A0A226MI72.1
#=GS H2TCV4_TAKRU/145-264      AC H2TCV4.1
#=GS A0A093FE34_GAVST/67-179   AC A0A093FE34.1
#=GS A0A1S3S4Y6_SALSA/134-264  AC A0A1S3S4Y6.1
#=GS A0A2K5IHF1_COLAP/147-277  AC A0A2K5IHF1.1
#=GS G3T029_LOXAF/142-261      AC G3T029.1
#=GS A0A0A0MVD8_PAPAN/149-268  AC A0A0A0MVD8.2
#=GS S7PNQ5_MYOBR/198-270      AC S7PNQ5.1
#=GS A0A0F8AN50_LARCR/130-249  AC A0A0F8AN50.1
#=GS G1P9Z2_MYOLU/147-277      AC G1P9Z2.1
#=GS V8NXT0_OPHHA/122-252      AC V8NXT0.1
#=GS F1NMJ9_CHICK/147-277      AC F1NMJ9.2
#=GS A0A1A6HG24_NEOLE/85-197   AC A0A1A6HG24.1
#=GS G1TCI4_RABIT/142-261      AC G1TCI4.1
#=GS A0A2I4CIS6_9TELE/131-261  AC A0A2I4CIS6.1
#=GS A0A2D0PZ34_ICTPU/133-263  AC A0A2D0PZ34.1
#=GS A0A0A0MUA2_PAPAN/141-266  AC A0A0A0MUA2.2
#=GS H2TE42_TAKRU/93-220       AC H2TE42.1
#=GS A0A2K5H7M5_COLAP/126-245  AC A0A2K5H7M5.1
#=GS J9P349_CANLF/147-277      AC J9P349.1
#=GS H0V6S7_CAVPO/147-277      AC H0V6S7.2
#=GS H0X486_OTOGA/147-277      AC H0X486.1
#=GS H2R074_PANTR/126-245      AC H2R074.1
#=GS H2QWZ4_PANTR/142-261      AC H2QWZ4.2
#=GS L5L7Y5_PTEAL/126-245      AC L5L7Y5.1
#=GS F1QPM9_DANRE/134-253      AC F1QPM9.1
#=GS A0A091DCH8_FUKDA/142-267  AC A0A091DCH8.1
#=GS G3PKV8_GASAC/130-260      AC G3PKV8.1
#=GS A0A2K5L5N3_CERAT/140-259  AC A0A2K5L5N3.1
#=GS M7B3B8_CHEMY/158-288      AC M7B3B8.1
#=GS H2TE39_TAKRU/134-264      AC H2TE39.1
#=GS A0A1S2ZMB9_ERIEU/142-261  AC A0A1S2ZMB9.1
#=GS E1BEL4_BOVIN/126-245      AC E1BEL4.1
#=GS A0A093PY01_9PASS/141-260  AC A0A093PY01.1
#=GS E9QJS1_MOUSE/172-292      AC E9QJS1.1
#=GS A0A091P2W8_APAVI/141-260  AC A0A091P2W8.1
#=GS H3B0L6_LATCH/131-251      AC H3B0L6.1
#=GS A0A096P1M0_PAPAN/142-261  AC A0A096P1M0.2
#=GS F6RE38_HORSE/141-260      AC F6RE38.1
#=GS JAK2_CHICK/140-259        AC Q75R65.1
#=GS A0A093F367_TYTAL/141-260  AC A0A093F367.1
#=GS A0A1U7STL7_TARSY/141-260  AC A0A1U7STL7.1
#=GS A0A093GHG5_DRYPU/147-277  AC A0A093GHG5.1
#=GS D2HMR9_AILME/67-186       AC D2HMR9.1
#=GS F1S818_PIG/147-277        AC F1S818.3
#=GS M7B4M9_CHEMY/226-345      AC M7B4M9.1
#=GS H3ABD2_LATCH/138-257      AC H3ABD2.1
#=GS B4MCY4_DROVI/127-235      AC B4MCY4.1
#=GS A0A287A292_PIG/141-266    AC A0A287A292.1
#=GS K1R7D2_CRAGI/67-180       AC K1R7D2.1
#=GS A0A1L8H2U7_XENLA/138-268  AC A0A1L8H2U7.1
#=GS F6WC83_HORSE/142-267      AC F6WC83.1
#=GS G1M9G8_AILME/147-277      AC G1M9G8.1
#=GS A0A1V4KQA1_PATFA/173-292  AC A0A1V4KQA1.1
#=GS A0A091TPR4_9AVES/141-260  AC A0A091TPR4.1
#=GS A0A0G2K636_RAT/126-244    AC A0A0G2K636.1
#=GS A0A091GZ50_9AVES/140-259  AC A0A091GZ50.1
#=GS F1R5C7_DANRE/145-275      AC F1R5C7.1
#=GS A0A1L8HY58_XENLA/140-259  AC A0A1L8HY58.1
#=GS A0A1S3WAF8_ERIEU/147-277  AC A0A1S3WAF8.1
#=GS F1PBD0_CANLF/146-273      AC F1PBD0.2
#=GS M3Y5N7_MUSPF/142-267      AC M3Y5N7.1
#=GS K7GSE8_PIG/126-245        AC K7GSE8.1
#=GS A0A2I4CI85_9TELE/49-168   AC A0A2I4CI85.1
#=GS H2VE41_TAKRU/141-267      AC H2VE41.1
#=GS G3VR92_SARHA/126-245      AC G3VR92.1
#=GS F1QWX8_DANRE/119-238      AC F1QWX8.1
#=GS H2VE43_TAKRU/127-253      AC H2VE43.1
#=GS JAK2_PIG/142-261          AC O19064.1
#=GS A0A096MF50_POEFO/142-261  AC A0A096MF50.1
#=GS A0A093HE63_STRCA/141-260  AC A0A093HE63.1
#=GS A0A226N5B7_CALSU/245-304  AC A0A226N5B7.1
#=GS M3WBF6_FELCA/142-267      AC M3WBF6.1
#=GS H2M2I1_ORYLA/144-274      AC H2M2I1.1
#=GS L8YCU2_TUPCH/155-213      AC L8YCU2.1
#=GS A0A2I3SYV7_PANTR/142-261  AC A0A2I3SYV7.1
#=GS A0A091TQI1_PHALP/141-260  AC A0A091TQI1.1
#=GS I3N6E8_ICTTR/147-277      AC I3N6E8.2
#=GS A0A218U7X2_9PASE/133-252  AC A0A218U7X2.1
#=GS A0A096LUR2_POEFO/129-259  AC A0A096LUR2.1
#=GS G1P7K0_MYOLU/23-142       AC G1P7K0.1
#=GS A0A093QCV4_9PASS/146-276  AC A0A093QCV4.1
#=GS A0A093CU52_TAUER/141-260  AC A0A093CU52.1
#=GS A0A2G9RUE2_LITCT/1-81     AC A0A2G9RUE2.1
#=GS H2R6D4_PANTR/141-266      AC H2R6D4.2
#=GS G7PZ76_MACFA/141-266      AC G7PZ76.1
#=GS S9X5J1_CAMFR/263-393      AC S9X5J1.1
#=GS A0A091I5H9_CALAN/141-260  AC A0A091I5H9.1
#=GS A0A091EJU9_CORBR/140-259  AC A0A091EJU9.1
#=GS G1PKC8_MYOLU/146-271      AC G1PKC8.1
#=GS A0A226F4F6_FOLCA/111-222  AC A0A226F4F6.1
#=GS A0A151ML25_ALLMI/146-209  AC A0A151ML25.1
#=GS F6TJE9_HORSE/145-216      AC F6TJE9.1
#=GS A0A087XSD4_POEFO/144-263  AC A0A087XSD4.2
#=GS S5RRC4_SALSA/134-264      AC S5RRC4.1
#=GS F6WH53_MONDO/140-259      AC F6WH53.2
#=GS A0A1S3LTU5_SALSA/1-81     AC A0A1S3LTU5.1
#=GS A0A1S3KQH9_SALSA/175-294  AC A0A1S3KQH9.1
#=GS A0A091FRB5_CORBR/95-221   AC A0A091FRB5.1
#=GS A0A226PRN9_COLVI/255-385  AC A0A226PRN9.1
#=GS W5PVH1_SHEEP/142-261      AC W5PVH1.1
#=GS A0A1U7QD80_MESAU/142-261  AC A0A1U7QD80.1
#=GS H3DMJ5_TETNG/1-92         AC H3DMJ5.1
#=GS A0A2I2V2G4_FELCA/126-245  AC A0A2I2V2G4.1
#=GS A0A1S3LVA6_SALSA/145-275  AC A0A1S3LVA6.1
#=GS K7FRF6_PELSI/170-300      AC K7FRF6.1
#=GS M3ZWG4_XIPMA/133-252      AC M3ZWG4.1
#=GS A0A0P7WCB5_9TELE/141-249  AC A0A0P7WCB5.1
#=GS F1S3L9_PIG/141-266        AC F1S3L9.2
#=GS A0A091L3K5_CATAU/38-168   AC A0A091L3K5.1
#=GS A0A2K5H7P1_COLAP/126-245  AC A0A2K5H7P1.1
#=GS A0A2K5JYV7_COLAP/142-261  AC A0A2K5JYV7.1
#=GS I3IZB2_ORENI/163-290      AC I3IZB2.1
#=GS A0A0D9R8Z9_CHLSB/140-259  AC A0A0D9R8Z9.1
#=GS G5B225_HETGA/142-267      AC G5B225.1
#=GS G3H6C9_CRIGR/142-267      AC G3H6C9.1
#=GS F6YLX1_MACMU/147-277      AC F6YLX1.2
#=GS A0A1S3PI02_SALSA/144-263  AC A0A1S3PI02.1
#=GS A0A093QW73_PHACA/141-260  AC A0A093QW73.1
#=GS H2SBF4_TAKRU/1-48         AC H2SBF4.1
#=GS A0A1U8DSZ3_ALLSI/128-247  AC A0A1U8DSZ3.1
#=GS A0A2I4BPV4_9TELE/143-273  AC A0A2I4BPV4.1
#=GS M7AIF3_CHEMY/73-192       AC M7AIF3.1
#=GS H2VE42_TAKRU/131-257      AC H2VE42.1
#=GS G3WN84_SARHA/147-277      AC G3WN84.1
#=GS A0A2K5KJN2_CERAT/141-266  AC A0A2K5KJN2.1
#=GS G1KI54_ANOCA/147-277      AC G1KI54.2
#=GS A0A091KC07_COLST/141-260  AC A0A091KC07.1
#=GS W4Z1N2_STRPU/114-214      AC W4Z1N2.1
#=GS A0A091W206_NIPNI/95-225   AC A0A091W206.1
#=GS W5L4R3_ASTMX/135-254      AC W5L4R3.1
#=GS L9KPJ3_TUPCH/142-261      AC L9KPJ3.1
#=GS I3J7Z7_ORENI/157-276      AC I3J7Z7.1
#=GS JAK1_MOUSE/147-275        AC P52332.1
#=GS A0A1U7R5X2_MESAU/147-277  AC A0A1U7R5X2.1
#=GS A0A1D5PS66_CHICK/130-249  AC A0A1D5PS66.1
#=GS F7EV03_XENTR/131-250      AC F7EV03.1
#=GS L9L1A5_TUPCH/126-228      AC L9L1A5.1
#=GS A0A1U8DCB6_ALLSI/159-289  AC A0A1U8DCB6.1
#=GS A0A1L8HXG0_XENLA/131-250  AC A0A1L8HXG0.1
#=GS A0A087XMA3_POEFO/132-259  AC A0A087XMA3.1
#=GS A0A2K5ITF8_COLAP/141-266  AC A0A2K5ITF8.1
#=GS A0A1S3QZS8_SALSA/137-267  AC A0A1S3QZS8.1
#=GS A0A091GBI7_9AVES/95-225   AC A0A091GBI7.1
#=GS A0A226MBH8_CALSU/86-216   AC A0A226MBH8.1
#=GS G1NGZ6_MELGA/147-277      AC G1NGZ6.2
#=GS H2VE39_TAKRU/150-276      AC H2VE39.1
#=GS A0A0D9S727_CHLSB/147-277  AC A0A0D9S727.1
#=GS A0A1S3QZA5_SALSA/137-267  AC A0A1S3QZA5.1
#=GS A0A0R4ICU5_DANRE/134-253  AC A0A0R4ICU5.1
#=GS F1MCX4_BOVIN/142-267      AC F1MCX4.2
#=GS K1R7W9_CRAGI/201-315      AC K1R7W9.1
#=GS H2L7P4_ORYLA/144-263      AC H2L7P4.1
#=GS A0A151NJE5_ALLMI/147-277  AC A0A151NJE5.1
#=GS L5K6W6_PTEAL/154-284      AC L5K6W6.1
#=GS A0A1S3IPL9_LINUN/104-224  AC A0A1S3IPL9.1
#=GS A0A2D0PQM4_ICTPU/131-250  AC A0A2D0PQM4.1
#=GS G3US57_MELGA/1-57         AC G3US57.1
#=GS A0A2I4AUZ4_9TELE/144-263  AC A0A2I4AUZ4.1
#=GS A0A091ULX3_NIPNI/141-260  AC A0A091ULX3.1
#=GS G1RYT5_NOMLE/146-276      AC G1RYT5.2
#=GS A0A096MCU2_POEFO/144-263  AC A0A096MCU2.1
#=GS F1S936_PIG/126-245        AC F1S936.2
#=GS F7FSX3_ORNAN/59-178       AC F7FSX3.2
#=GS A0A226MI46_CALSU/130-249  AC A0A226MI46.1
#=GS A0A2I0MG33_COLLI/140-259  AC A0A2I0MG33.1
#=GS F7GS58_MACMU/113-221      AC F7GS58.2
#=GS F6X8E5_ORNAN/132-251      AC F6X8E5.1
#=GS A0A1L8GFQ7_XENLA/133-209  AC A0A1L8GFQ7.1
#=GS I3KJT0_ORENI/144-263      AC I3KJT0.1
#=GS H2V1W5_TAKRU/141-260      AC H2V1W5.1
#=GS F1N0D6_BOVIN/147-277      AC F1N0D6.2
#=GS A0A226MYM3_COLVI/124-186  AC A0A226MYM3.1
#=GS A0A2I3LH42_PAPAN/18-91    AC A0A2I3LH42.1
#=GS JAK2_MOUSE/142-261        AC Q62120.2
#=GS A0A1S3P9N7_SALSA/144-274  AC A0A1S3P9N7.1
#=GS W5LHR3_ASTMX/138-268      AC W5LHR3.1
#=GS A0A091CUK2_FUKDA/179-309  AC A0A091CUK2.1
#=GS H9H626_MONDO/79-209       AC H9H626.1
#=GS F1LR79_RAT/126-245        AC F1LR79.2
#=GS A0A094L2N6_9AVES/67-186   AC A0A094L2N6.1
#=GS G3W042_SARHA/139-269      AC G3W042.1
#=GS A0A2I4BES6_9TELE/137-256  AC A0A2I4BES6.1
#=GS K7GME4_PIG/147-277        AC K7GME4.9
#=GS A0A2K5NHQ0_CERAT/153-283  AC A0A2K5NHQ0.1
#=GS A0A2I3RSB7_PANTR/141-266  AC A0A2I3RSB7.1
#=GS T0M5G5_CAMFR/142-267      AC T0M5G5.1
#=GS H0YE41_HUMAN/1-45         AC H0YE41.8
#=GS A0A1U7RXD8_ALLSI/147-277  AC A0A1U7RXD8.1
#=GS A0A0F8AEQ5_LARCR/116-246  AC A0A0F8AEQ5.1
#=GS B4NE99_DROWI/160-279      AC B4NE99.2
#=GS TYK2_MOUSE/144-269        AC Q9R117.3
#=GS K7G2T9_PELSI/140-259      AC K7G2T9.1
#=GS F7GT47_MACMU/142-261      AC F7GT47.1
#=GS G1MVV3_MELGA/102-232      AC G1MVV3.1
#=GS I3K428_ORENI/138-257      AC I3K428.1
#=GS F7DRD4_MACMU/141-266      AC F7DRD4.2
#=GS H2SBF2_TAKRU/157-276      AC H2SBF2.1
#=GS F6TJR2_ORNAN/67-186       AC F6TJR2.1
#=GS F7DKS0_XENTR/134-264      AC F7DKS0.1
#=GS S7MJU2_MYOBR/70-189       AC S7MJU2.1
#=GS G3IEQ4_CRIGR/132-251      AC G3IEQ4.1
#=GS G3QWD9_GORGO/142-261      AC G3QWD9.2
#=GS I3K427_ORENI/131-250      AC I3K427.1
#=GS H3C837_TETNG/27-146       AC H3C837.1
#=GS H2N755_PONAB/147-277      AC H2N755.1
#=GS A0A1U7T2Q1_TARSY/132-187  AC A0A1U7T2Q1.1
#=GS A0A2I0MC95_COLLI/147-277  AC A0A2I0MC95.1
#=GS A0A1A6GPP0_NEOLE/78-208   AC A0A1A6GPP0.1
#=GS Q9TTJ0_PIG/142-261        AC Q9TTJ0.1
#=GS JAK3_MOUSE/126-245        AC Q62137.2
#=GS F7BLR3_HORSE/1-86         AC F7BLR3.1
#=GS E9PPF2_HUMAN/141-266      AC E9PPF2.1
#=GS A0A0R4J0R7_MOUSE/126-245  AC A0A0R4J0R7.1
#=GS A0A287A997_PIG/141-266    AC A0A287A997.1
#=GS F1Q6A2_DANRE/119-238      AC F1Q6A2.2
#=GS A0A091SDR0_NESNO/146-276  AC A0A091SDR0.1
#=GS A0A1U8C602_MESAU/146-271  AC A0A1U8C602.1
#=GS S7NZR3_MYOBR/155-280      AC S7NZR3.1
#=GS G3PZA6_GASAC/146-265      AC G3PZA6.1
#=GS A0A1V4J8Q4_PATFA/135-254  AC A0A1V4J8Q4.1
#=GS A0A226NGA7_CALSU/163-293  AC A0A226NGA7.1
#=GS A0A0A0MTV7_PAPAN/141-266  AC A0A0A0MTV7.2
#=GS M3YWH9_MUSPF/126-245      AC M3YWH9.1
#=GS W5Q3B2_SHEEP/142-267      AC W5Q3B2.1
#=GS A0A093J647_EURHL/147-277  AC A0A093J647.1
#=GS G1RCI3_NOMLE/142-261      AC G1RCI3.1
#=GS H0ZIA6_TAEGU/134-264      AC H0ZIA6.1
#=GS A0A0D9R4G8_CHLSB/141-266  AC A0A0D9R4G8.1
#=GS M3ZLD9_XIPMA/144-263      AC M3ZLD9.1
#=GS A0A218UJX7_9PASE/146-276  AC A0A218UJX7.1
#=GS G3PKI3_GASAC/141-260      AC G3PKI3.1
#=GS H2TE40_TAKRU/107-237      AC H2TE40.1
#=GS A0A091USR2_NIPNI/147-277  AC A0A091USR2.1
#=GS F7CMB7_XENTR/142-272      AC F7CMB7.1
#=GS F6W791_CALJA/147-277      AC F6W791.1
#=GS A0A2K5L5K0_CERAT/142-261  AC A0A2K5L5K0.1
#=GS A0A1V4KY01_PATFA/170-300  AC A0A1V4KY01.1
#=GS A0A087VNE1_BALRE/95-225   AC A0A087VNE1.1
#=GS G3U018_LOXAF/151-281      AC G3U018.1
#=GS G7NW22_MACFA/135-265      AC G7NW22.1
#=GS G3RIC1_GORGO/126-245      AC G3RIC1.2
#=GS A0A091W7X1_NIPNI/108-227  AC A0A091W7X1.1
#=GS A0A1U7RLB6_ALLSI/140-259  AC A0A1U7RLB6.1
#=GS F7D542_ORNAN/174-247      AC F7D542.2
#=GS A0A2I4CIS9_9TELE/131-261  AC A0A2I4CIS9.1
#=GS G1SQL4_RABIT/147-277      AC G1SQL4.2
#=GS A0A1L8GLW3_XENLA/133-263  AC A0A1L8GLW3.1
#=GS A0A1S3FJH6_DIPOR/147-277  AC A0A1S3FJH6.1
#=GS JAK2_PONAB/142-261        AC Q5RB23.1
#=GS H2LQD3_ORYLA/133-254      AC H2LQD3.1
#=GS A0A087XVK1_POEFO/145-275  AC A0A087XVK1.1
#=GS S9YWR6_CAMFR/143-262      AC S9YWR6.1
#=GS L5LTA8_MYODS/142-267      AC L5LTA8.1
#=GS A0A1U7SPN9_TARSY/141-260  AC A0A1U7SPN9.1
#=GS A0JM01_XENTR/140-259      AC A0JM01.1
#=GS U3KDU1_FICAL/146-276      AC U3KDU1.1
#=GS B4JJT9_DROGR/131-253      AC B4JJT9.1
#=GS F8W4H3_DANRE/134-264      AC F8W4H3.1
#=GS F6TV83_CIOIN/137-264      AC F6TV83.2
#=GS W5MIP2_LEPOC/145-273      AC W5MIP2.1
#=GS G3P1H3_GASAC/131-250      AC G3P1H3.1
#=GS W5KTH7_ASTMX/145-279      AC W5KTH7.1
#=GS M3ZDE9_XIPMA/132-259      AC M3ZDE9.1
#=GS A0A1S3KQI9_SALSA/175-294  AC A0A1S3KQI9.1
#=GS A0A1V4KXU7_PATFA/170-300  AC A0A1V4KXU7.1
#=GS G3RK14_GORGO/147-277      AC G3RK14.1
#=GS F7DHF9_CALJA/142-261      AC F7DHF9.1
#=GS A0A1V4JXL8_PATFA/147-277  AC A0A1V4JXL8.1
#=GS A0A218VAM0_9PASE/140-259  AC A0A218VAM0.1
#=GS A0A151ML06_ALLMI/162-225  AC A0A151ML06.1
#=GS A0A2D0SYU4_ICTPU/126-245  AC A0A2D0SYU4.1
#=GS M3ZJ44_XIPMA/145-275      AC M3ZJ44.1
#=GS F7F934_MONDO/126-244      AC F7F934.1
#=GS A0A2K5IGU5_COLAP/153-283  AC A0A2K5IGU5.1
#=GS B1ASP2_MOUSE/147-277      AC B1ASP2.1
#=GS A0A091UD74_PHORB/141-260  AC A0A091UD74.1
#=GS A0A0N8K0F6_9TELE/144-263  AC A0A0N8K0F6.1
#=GS A0A093CGK4_TAUER/41-171   AC A0A093CGK4.1
#=GS H2L7P7_ORYLA/141-260      AC H2L7P7.1
#=GS H2M2B1_ORYLA/155-274      AC H2M2B1.1
#=GS G3QT84_GORGO/141-266      AC G3QT84.2
#=GS H2PS83_PONAB/142-261      AC H2PS83.1
#=GS G1KHZ7_ANOCA/140-270      AC G1KHZ7.2
#=GS A0A1S3LTD3_SALSA/140-259  AC A0A1S3LTD3.1
#=GS A0A1D2NKP5_ORCCI/91-202   AC A0A1D2NKP5.1
#=GS A0A096N179_PAPAN/146-276  AC A0A096N179.2
#=GS A0A1S3FBE8_DIPOR/143-206  AC A0A1S3FBE8.1
#=GS A0A0P7WH47_9TELE/160-258  AC A0A0P7WH47.1
#=GS A0A2I0LJ08_COLLI/171-301  AC A0A2I0LJ08.1
#=GS A0A091KK52_9GRUI/141-260  AC A0A091KK52.1
#=GS A0A1S3LTH7_SALSA/140-259  AC A0A1S3LTH7.1
#=GS K7FRH1_PELSI/148-278      AC K7FRH1.1
#=GS H2SBF3_TAKRU/89-204       AC H2SBF3.1
#=GS E9PM19_HUMAN/1-81         AC E9PM19.1
#=GS A0A1U8DDU7_ALLSI/159-276  AC A0A1U8DDU7.1
#=GS F6X395_ORNAN/38-168       AC F6X395.1
#=GS I3JQC0_ORENI/145-275      AC I3JQC0.1
#=GS H3CH80_TETNG/157-276      AC H3CH80.1
#=GS A0A1S3LUJ9_SALSA/140-259  AC A0A1S3LUJ9.1
#=GS A0A1A6HMC7_NEOLE/146-271  AC A0A1A6HMC7.1
#=GS H2TE41_TAKRU/117-251      AC H2TE41.1
#=GS A0A2I4CI67_9TELE/144-263  AC A0A2I4CI67.1
#=GS A0A096LWM8_POEFO/133-252  AC A0A096LWM8.1
#=GS A0A1U7R3C7_MESAU/146-271  AC A0A1U7R3C7.1
#=GS A0A091EVH4_CORBR/145-275  AC A0A091EVH4.1
#=GS JAK2_HUMAN/142-261        AC O60674.2
#=GS JAK2_HUMAN/142-261        DR PDB; 4Z32 F; 142-261;
#=GS JAK2_HUMAN/142-261        DR PDB; 4Z32 A; 142-261;
#=GS JAK2_HUMAN/142-261        DR PDB; 4Z32 H; 142-261;
#=GS JAK2_HUMAN/142-261        DR PDB; 4Z32 E; 142-261;
#=GS JAK2_HUMAN/142-261        DR PDB; 4Z32 B; 142-261;
#=GS JAK2_HUMAN/142-261        DR PDB; 4Z32 C; 142-261;
#=GS JAK2_HUMAN/142-261        DR PDB; 4Z32 G; 142-261;
#=GS JAK2_HUMAN/142-261        DR PDB; 4Z32 D; 142-261;
#=GS I3M210_ICTTR/155-280      AC I3M210.2
#=GS W5PK80_SHEEP/147-277      AC W5PK80.1
#=GS A0A2K5IU17_COLAP/141-266  AC A0A2K5IU17.1
#=GS A0A093QTD9_PYGAD/141-260  AC A0A093QTD9.1
#=GS A0A151M8K3_ALLMI/135-254  AC A0A151M8K3.1
#=GS A0A226MBR6_CALSU/292-422  AC A0A226MBR6.1
#=GS H3CXH8_TETNG/121-240      AC H3CXH8.1
#=GS G3TF05_LOXAF/86-207       AC G3TF05.1
#=GS A0A2D0R0L4_ICTPU/129-248  AC A0A2D0R0L4.1
#=GS A0A0N8JZU0_9TELE/110-241  AC A0A0N8JZU0.1
#=GS JAK3_HUMAN/126-245        AC P52333.2
#=GS G1T864_RABIT/139-264      AC G1T864.1
#=GS W5MIN0_LEPOC/145-277      AC W5MIN0.1
#=GS A0A2I3LGP0_PAPAN/147-277  AC A0A2I3LGP0.1
#=GS G1PL96_MYOLU/142-261      AC G1PL96.1
#=GS A0A091T8G5_PHALP/95-225   AC A0A091T8G5.1
#=GS G5E852_MOUSE/142-261      AC G5E852.1
#=GS JAK1_HUMAN/147-277        AC P23458.2
#=GS JAK1_HUMAN/147-277        DR PDB; 5IXD A; 147-277;
#=GS JAK1_HUMAN/147-277        DR PDB; 5IXI A; 147-277;
#=GS JAK1_HUMAN/147-277        DR PDB; 5L04 A; 147-277;
#=GS H2P0I2_PONAB/1-111        AC H2P0I2.1
#=GS A0A1S3WF45_ERIEU/142-267  AC A0A1S3WF45.1
#=GS W5ML83_LEPOC/152-282      AC W5ML83.1
#=GS F7B2N9_HORSE/126-244      AC F7B2N9.1
#=GS A0A091IV20_EGRGA/141-260  AC A0A091IV20.1
#=GS F6VBG6_HORSE/142-213      AC F6VBG6.1
#=GS H0X195_OTOGA/126-245      AC H0X195.1
#=GS A0A2I2UMB9_FELCA/126-245  AC A0A2I2UMB9.1
#=GS G1RNJ0_NOMLE/141-266      AC G1RNJ0.3
#=GS A0A0Q3QW93_AMAAE/125-244  AC A0A0Q3QW93.1
#=GS A0A286ZVG5_PIG/141-266    AC A0A286ZVG5.1
#=GS M3W7U9_FELCA/126-245      AC M3W7U9.2
#=GS L5L284_PTEAL/155-280      AC L5L284.1
#=GS A0A1U7S0K0_ALLSI/138-268  AC A0A1U7S0K0.1
#=GS F1PIY7_CANLF/147-277      AC F1PIY7.2
#=GS A0A2D0RWX2_ICTPU/141-271  AC A0A2D0RWX2.1
#=GS F7BLF9_HORSE/1-86         AC F7BLF9.1
#=GS A0A2K5JYU7_COLAP/142-261  AC A0A2K5JYU7.1
#=GS U3IX13_ANAPL/82-212       AC U3IX13.1
#=GS H2TCV3_TAKRU/140-259      AC H2TCV3.1
#=GS H2VE44_TAKRU/119-245      AC H2VE44.1
#=GS A0A1S3MPK9_SALSA/129-248  AC A0A1S3MPK9.1
#=GS D2GV17_AILME/126-245      AC D2GV17.1
#=GS A0A091K588_COLST/76-201   AC A0A091K588.1
#=GS A0A0F8AHG9_LARCR/147-274  AC A0A0F8AHG9.1
#=GS A0A1U7U068_TARSY/147-277  AC A0A1U7U068.1
#=GS W5M4D5_LEPOC/132-251      AC W5M4D5.1
#=GS G3H4C9_CRIGR/66-185       AC G3H4C9.1
#=GS M3VXL7_FELCA/147-277      AC M3VXL7.2
#=GS F6SFF7_CIOIN/188-291      AC F6SFF7.2
#=GS F1NQU4_CHICK/140-259      AC F1NQU4.2
#=GS J9P769_CANLF/126-245      AC J9P769.1
#=GS A0A2D0R906_ICTPU/131-261  AC A0A2D0R906.1
#=GS S7PNQ5_MYOBR/283-352      AC S7PNQ5.1
#=GS A0A091NKY1_APAVI/1-95     AC A0A091NKY1.1
#=GS F6V3I2_MONDO/137-267      AC F6V3I2.1
#=GS L5K8D1_PTEAL/140-259      AC L5K8D1.1
#=GS S7MWR8_MYOBR/162-292      AC S7MWR8.1
#=GS G1LYZ3_AILME/146-271      AC G1LYZ3.1
#=GS A0A091XF04_OPIHO/141-260  AC A0A091XF04.1
#=GS A0A1U7SIM6_TARSY/185-310  AC A0A1U7SIM6.1
#=GS A0A0A0AT86_CHAVO/141-260  AC A0A0A0AT86.1
#=GS A0A2I3MPX7_PAPAN/141-266  AC A0A2I3MPX7.1
#=GS W5L4W4_ASTMX/129-248      AC W5L4W4.1
#=GS I3MAE0_ICTTR/126-245      AC I3MAE0.2
#=GS G3STB4_LOXAF/147-271      AC G3STB4.1
#=GS A0A1A6H8C5_NEOLE/59-178   AC A0A1A6H8C5.1
#=GS JAK1_DANRE/145-275        AC O12990.1
#=GS G3QSH5_GORGO/126-245      AC G3QSH5.2
#=GS J9JIK9_PIG/142-261        AC J9JIK9.2
#=GS A0A087QSD3_APTFO/141-260  AC A0A087QSD3.1
#=GS H3DL74_TETNG/147-273      AC H3DL74.1
#=GS M3ZMT4_XIPMA/146-265      AC M3ZMT4.1
#=GS H0X425_OTOGA/141-266      AC H0X425.1
#=GS H3DDQ1_TETNG/27-146       AC H3DDQ1.1
#=GS A0A0F8C2P5_LARCR/124-243  AC A0A0F8C2P5.1
#=GS W5M4B2_LEPOC/139-258      AC W5M4B2.1
#=GS JAK3_RAT/126-245          AC Q63272.1
#=GS I3M8D2_ICTTR/142-261      AC I3M8D2.2
#=GS A0A093EPV8_GAVST/147-277  AC A0A093EPV8.1
#=GS G3PKW3_GASAC/135-265      AC G3PKW3.1
#=GS B4L4A0_DROMO/128-233      AC B4L4A0.1
#=GS A0A091I984_CALAN/146-276  AC A0A091I984.1
#=GS A0A1S3G4P2_DIPOR/126-245  AC A0A1S3G4P2.1
#=GS K7E1N4_MONDO/137-267      AC K7E1N4.1
#=GS M3XNR7_MUSPF/147-277      AC M3XNR7.1
#=GS G1R1P8_NOMLE/126-226      AC G1R1P8.3
#=GS A0A0F8AEI9_LARCR/116-246  AC A0A0F8AEI9.1
#=GS I3MJ48_ICTTR/147-277      AC I3MJ48.2
#=GS A0A2K5KJN0_CERAT/141-266  AC A0A2K5KJN0.1
#=GS A0A2I3NI09_PAPAN/142-261  AC A0A2I3NI09.1
#=GS G3NVW0_GASAC/149-279      AC G3NVW0.1
#=GS A0A1S3ADN5_ERIEU/126-245  AC A0A1S3ADN5.1
#=GS A0A2I2Y6E6_GORGO/142-261  AC A0A2I2Y6E6.1
#=GS A0A091HKF2_BUCRH/141-260  AC A0A091HKF2.1
#=GS A0A1U8D4W6_ALLSI/79-209   AC A0A1U8D4W6.1
#=GS A0A1S3P9S9_SALSA/159-289  AC A0A1S3P9S9.1
#=GS L5LC09_MYODS/92-211       AC L5LC09.1
#=GS A0A1S3KQJ9_SALSA/26-145   AC A0A1S3KQJ9.1
#=GS H0Z3Y5_TAEGU/141-260      AC H0Z3Y5.1
#=GS G3SSY6_LOXAF/149-274      AC G3SSY6.1
#=GS A0A091R6W6_MERNU/147-277  AC A0A091R6W6.1
#=GS D3ZD03_RAT/146-271        AC D3ZD03.1
#=GS A0A1D5PK82_CHICK/1-38     AC A0A1D5PK82.1
#=GS A0A087V8Q7_BALRE/67-186   AC A0A087V8Q7.1
#=GS H2LLN7_ORYLA/133-263      AC H2LLN7.1
#=GS M3Y0T4_MUSPF/140-259      AC M3Y0T4.1
#=GS U3IAY8_ANAPL/142-261      AC U3IAY8.1
#=GS A0A091GNU7_BUCRH/148-278  AC A0A091GNU7.1
#=GS U3IXD0_ANAPL/1-120        AC U3IXD0.1
A0A1S3KKN4_SALSA/145-275             ............i-PLLDAASLDYLFAQ.GQND...FQKGL.AVVRCPQSEAEQHEIEN....E..CLGMAVLAITHYAMTREI..PLSTA.SNEI...S.........Y.KRFIPEKLNRQIKQRNILTRLRINNVFKNFLN.EFN..S..RTVQDSNITLYDLKIKYLSTLESL....................................................
H0VSL1_CAVPO/126-245                 .............SSIVDLPVLEHLFAQ.HRSD...LVNGR.LAVGLSLKEQG------....E..CLSLAVLDLARMAREQGR..PLQEM.LRTV...S.........Y.KACLPHRLRDLIQGLSFVTRKRIRRTVRRALR.RVA..-..----SCQADKHSLMAKYVMDLERL....................................................
A0A087YP74_POEFO/150-269             .............SPVMDDCVMAYLFAQ.WRSD...FLNGW.VHIPVSHEAQE------....E..CLGMAVLDMMRLAKESDL..SPVDI.YNDT...S.........Y.KSFLPRCMRNRIQEYNLLTRKRIRYRFRRFIQ.QFS..-..----ECKATVCNLKLKYLMNLEML....................................................
G3WQ34_SARHA/142-261                 ............a-PLLDDFVMSYLFAQ.WRDD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDIMRIAKEKDQ..TPLAV.YNST...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARILKLKYLINLETL....................................................
H2V1W4_TAKRU/141-260                 .............SPVFDDYVMSYLFSQ.WRND...FVNGL.VKIPSSHESQE------....E..CLGMAVLDMTRTAKESQL..SPLDI.YHTM...S.........Y.KSFLPKEMRAQIQDCNFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISMESL....................................................
A0A0P7UXN8_9TELE/143-273             .............TPLLDAASLEYLFSQ.GQYD...FVKGL.APLRIPLSESEAHEIEN....E..CLGMAVLAISHYAINKSV..SLSGM.AADI...S.........Y.KKYIPESLNKTIKQRNFLTRIRINNVFKNFLN.EFN..S..KTIQDSHVTTHDLKVKYLSTLETL....................................................
S9YP10_CAMFR/140-259                 ............a-PLLDDFVMSYLFAQ.WRHD...FLHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLDI.YSSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
H2VE40_TAKRU/170-237                 ........plffl---------------.----...-----.-----------------....-..------------------..-----.---S...S.........Y.KRFIPESLNRSIKQRSFMTRIRINNVFKKFLS.EFH..Q..RTIRDSNITPYDLKIKYLATLEGL....................................................
H0X6H8_OTOGA/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVYGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A099ZDF1_TINGU/141-260             .............SPVLDDIVMSYLFAQ.WRDD...FLNGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A2K5L3K1_CERAT/113-232             .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LAVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
A0A0D9QZJ5_CHLSB/71-190              .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
H0V2Z6_CAVPO/142-267                 ............i-QVLDPASFEYLFEQ.GKYE...FVNDV.ISLWELSSEEEIHHFKN....E..SLGMAFLHLCHLAFCRNV..PLEEV.AKEI...S.........F.TRCIPSSFRQQIRQHSVLTRLRLRSVFRRFVR.TFR..-..----TAQLSRRAVMVKYLATLEHL....................................................
E2RG40_CANLF/126-245                 .............SAILDLPVLEHLFAQ.HRND...LVSGR.FSVGLSLKEQD------....E..YLSLAVLDLARMAREQAQ..QPEEL.LKTV...S.........Y.KVCLPPDLRDLIQGLSFVTRKRIRRMVRRALR.RVT..-..----ACQADRHSLMAKYIMDLERL....................................................
H2TCV2_TAKRU/129-248                 .............SPVLDHSGIAYLFAQ.LRSD...FTTGE.AGLSPPLTNQD------....E..CLGLAVLDLWRLAKEKRQ..SVKDL.CKSV...S.........Y.KSCLPKSHRADIEKRNWVERYRIRNTLKHFLK.KIG..-..----NCPVDDCNLKLMYLTEL---agi.................................................
A0A099YZG4_TINGU/147-286             .............TPILDAHSLEYIFAQ.GQYD...LVKGL.APVRDPKNDQEVHEIEN....E..CLGMAVLAISHHAIKKNM..KLPEL.PKDI...RqvritycslY.KHYIPETLNKTIRQRNFLTRIRINNVFKDFLK.EFN..N..KTICDTNVSPHDLKVKYLSTMETL....................................................
A0A0P7V4D3_9TELE/149-279             .............TPLLDGASLEYLFAQ.GQQD...FLKGL.APVRRPQDEAEVHDIEN....E..CLGMAVLAISHYAISRNL..PLSGV.ARDI...S.........Y.KKYIPESLNRSIKQRNLLTRIRINNVFKNFLN.EFN..N..KTILDSNVTAHDLKVKYLSTLETL....................................................
G5B4Y4_HETGA/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAI.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
G5BSN6_HETGA/315-445                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKV..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..TTICDSSVSTHDLKVKYLATLETL....................................................
A0A2I3T122_PANTR/126-245             .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LPMGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
A0A0Q3QCQ8_AMAAE/138-268             ............a-ALLDRASFEYLFEQ.GKYE...FINDV.ASLRELPSEQEVQRFKN....E..SLGMAVLHLSHMALRKGI..SLEEV.ARKY...S.........F.KECIPRSFCRQIQQNNFLTKFRMKKVFRKFLQ.RFQ..R..HTVGTGKLTAQDIMYKYLATLEHL....................................................
H2PZ66_PANTR/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
H9H0M3_MELGA/1-114                   ............p-------VIDYLFAQ.SRSD...FIAGR.MELALSLAGQE------....E..CLSLAVLDMLRIAKEKWQ..SPEQV.FSCI...S.........Y.KSCIPEPLRCQIQQHSFLTRKRIRRRVAQSLR.RMG..-..----GCRADGRCLKLKYLLDLERL....................................................
A0A0Q3U4V2_AMAAE/157-287             .............TPILDANSXEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.LKDM...S.........Y.KHYIPETLNXTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVTSRDLKVKYLSTMETL....................................................
M3XFX5_FELCA/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FLHGW.IKIPVTHETQE------....E..CLGMAVLDMMRLAKEKDQ..TPLDI.YSSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
A0A0Q3V9G8_AMAAE/139-258             .............SPVLDDVVMSYLFAQ.WRAD...FLDGW.VQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A286XLG2_CAVPO/126-245             .............SSIVDLPVLEHLFAQ.HRSD...LVNGR.LAVGLSLKEQG------....E..CLSLAVLDLARMAREQGR..PLQEM.LRTV...S.........Y.KACLPHRLRDLIQGLSFVTRKRIRRTVRRALR.RVA..-..----SCQADKHSLMAKYVMDLERL....................................................
A0A087R0W7_APTFO/147-277             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNM..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTIGDSSVSPRDLKVKYLSTMETL....................................................
H2VE38_TAKRU/141-267                 .............TPLLDAASLDYLFYQ.GQHS...FHKGL.VPLRKSHSDAEQHEIEN....E..CLGMAVLAITHT---TNM..SVPG-.SHDI...S.........Y.KRFIPESLNRSIKQRSFMTRIRINNVFKKFLS.EFH..Q..RTIRDSNITPYDLKIKYLATLEGL....................................................
Q9TTJ1_PIG/135-265                   .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A093GIU2_DRYPU/141-260             .............SPVLDDLVMSYLFAQ.WRAD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSM...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLENL....................................................
A0A226N5B7_CALSU/160-248             .............SPVLDDLVMSYLFAQ.WRDD...FLGGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAV.YNSV...S.........Y.KMFLPKCVRAKIQEYHILTRKRI---------.---..-..------------------------s...................................................
W5LAY4_ASTMX/143-262                 ............a-PVLDDITMAYLFAQ.WRSD...FVDGS.VSVPVSHDAQE------....E..CLGMAVLDMMRIAKEKSR..SPVDI.YNNS...S.........Y.KSFLPKGMRAHIQDYHFVTRKRIRYRFRKFIQ.QFS..-..----HCKVGLRDLKLKYLASLENL....................................................
F6QBA9_CALJA/77-202                  ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALHHGV..PLEEV.AKKT...S.........F.KDCIPHSFRRQIRQHNALTRLRLRNVFRRFLR.DFQ..-..----PGCLSQQMVMVKYLATLERL....................................................
K7FHA5_PELSI/71-177                  .............TAVLDCPTIDYLFAQ.SRSD...FISGR.MEVALSLQEQE------....E..CLSLAVLDMLRMAKERKW..SPEEI.FSCS...S.........Y.K------LRQQIQQHSFLTRKRIRRKFHKSLQ.KIS..-..-----------SCKLKYLMDLEK-r...................................................
B0V237_DANRE/127-246                 ............f-AVLDYAVIDYVFAQ.SRSD...FVTGC.GGISPALSLQQ------....E..CLGLAVLDLWRLAKERNQ..SLAEI.CNTT...S.........Y.KSCLPETHRQDIQRMNRLARYQIRKTLKRFLK.KLG..-..----KCSAGERSLKLKYLMKLSEL....................................................
G7PSF3_MACFA/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPECIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A087VRZ8_BALRE/147-277             .............TPILDASSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.PKDV...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSSRDLKVKYLSTMETL....................................................
A0A2I0LKC6_COLLI/134-253             .............SPILDYPVIDYLFAQ.SRSD...FIGGR.VAVALSLPTQE------....E..CLSLAVLDMLRIAKEEQQ..SPGQV.FSYV...S.........Y.KSCIPAPLRFQIQQHNFLTRKRIRRRFSKSLR.KIG..-..----GCQTDGRYLKLKYLLDLERL....................................................
A0A2K5L3H2_CERAT/126-245             .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LAVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
E2RPW6_CANLF/142-261                 ............a-PLLDDFVMAYLFAQ.WRHD...FLHGW.IKIPVTHETQE------....E..CLGMAVLDMMRLAKEKDQ..TPLDI.YSSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
E1BCP6_BOVIN/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FLHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKNQ..TPLDI.YSSI...S.........Y.KTFLPKCVRAKIQEYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
A0A2I3RU79_PANTR/145-275             .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
U3K7L6_FICAL/140-259                 .............SPVLDDLVMSYLFAQ.WRAD...FLDGW.VQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPMAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A091DWB5_FUKDA/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAI.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A1B0GTR9_HUMAN/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
W4ZL99_STRPU/114-214                 ...........fm--LLEENVVNYMFCQ.YRES...FLNDE.F----MGLSTE------....E..SLGLMVLDFMQHVKEDGT..SLTNL.NGRL...R.........F.GRFLPKSLNEGL---SWWDKRKLRRKVRTALT.DFR..-..------------------------ddpretfa............................................
H2NY19_PONAB/125-244                 .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMAREQSQ..RPGEL.LKTI...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
G3V9W2_RAT/147-277                   .............TPLLDASSLEYLFAQ.GQYD...LIKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
G3U3K6_LOXAF/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVCGW.IKLPVTHETQE------....E..CLGLAVLDMMRIAKEKGQ..TPLAI.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLEAL....................................................
TYK2_HUMAN/141-266                   ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSTEEEIHHFKN....E..SLGMAFLHLCHLALRHGI..PLEEV.AKKT...S.........F.KDCIPRSFRRHIRQHSALTRLRLRNVFRRFLR.DFQ..-..----PGRLSQQMVMVKYLATLERL....................................................
#=GR TYK2_HUMAN/141-266        SS    ............---S--HHHHHHHHHH.HHHH...HHTTS.S-GGG--SHHHHHHHHH....H..HHHHHHHHHHHHHHHHT-..-HHHH.HHHS...-.........G.GGSS-HHHHHHHHHS-HHHHHHHHHHHHHHHH.T--..-..----TTS--HHHHHHHHHHHHHHH....................................................
A0A2K5NH39_CERAT/147-277             .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
G1KCE0_ANOCA/140-259                 .............TPVLDDIIMSYLFAQ.WRED...FVHGW.VKMAVTHETQE------....E..CLGMAVLDIMRMAKEKDQ..TPLSI.YNSV...S.........Y.KMFLPKCIREKIQDYHILTRKRIRYRFRRFIQ.RFG..-..----QCNASARNLKLKYLINLETL....................................................
M7AKN2_CHEMY/458-588                 ............g-ALLDKSSFEYLFEQ.GKYE...FINDV.VSLKDLQSEQEIHRFKN....E..SLGMAVLHLSHMALKRGV..SLEEV.AKKT...S.........F.KGCIPRSFCRQIQQNNYLTRFRMRNVFRKFVQ.RFQ..R..HTVSAGKLTEQDVMYKYLATLENL....................................................
W5MVJ9_LEPOC/140-259                 .............SPVLDDSVMSYLFAQ.WRSD...FVDGW.VKIAISHETQE------....E..CLGMAVLDMMRIAKEKDQ..SPLDI.YNAM...S.........Y.KSFLPKDMRARIQDYHIVTRKRIRYRFRRFIQ.QFS..-..----QCKAAARDLKLKYLINLEML....................................................
G3HY52_CRIGR/135-265                 .............TPLLDASSLEYLFAQ.GQYD...LIKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRLRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A1D5PTI3_CHICK/1-38                .............---------------.----...-----.-----------------....-..------------------..-----.----...-.........-.----------------------MKNVFRKFVR.RFQ..R..HTVGAGTLTEEDVMFKYLATLELL....................................................
A0A226MYM3_COLVI/26-128              .............TAVLDRASFEYLFEQ.GKFD...FINDV.ASLTDFRTETEVQRFKN....E..SLGMAVLHLAHIALRSGR..CLQDV.ARKY...S.........F.QECIPRSFRHQIQRNSAVTRFRMRNVFRSF--.---..-..------------------------qe..................................................
A0A091Q3A9_LEPDC/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A091RTW2_9GRUI/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
W5KTR4_ASTMX/149-279                 ............a-PLLEMSSLEYLFAQ.AKCD...FVNDV.VSLDELVDEVQQTCFKN....E..SLGMAVLHLSHRALQNQS..TLQDV.AKHT...S.........F.LRCIPRSFARHIARDNFLTKFRIRRVFSEFVR.SFQ..Q..HTVGQGHLGAQEVMYKYLSTLERL....................................................
A0A151N0Y0_ALLMI/138-268             .............SALLDRASFEYLFEQ.GKFE...FVNDV.ASLQDLATEQDLHRFKN....E..SLGMAVLHLSHLALRRGL..SLEEA.AKKC...S.........F.KDCIPRSFRRQIQQSSSLTRLRLRSVFRRFVQ.HFQ..R..HTVGAGRLTEQGVMYKYLATLESL....................................................
A0A1U8CMQ3_MESAU/140-259             .............SAILDSHVLEHLFAQ.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLAQMAREQAQ..RPGEL.LKAV...S.........Y.KACLPPGLRDLIQGLSFVTRRRIRRTVLQALR.RVV..-..----ACQADRYSLMAKYILDLERL....................................................
A0A093H4Q9_STRCA/147-277             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APVRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNM..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKDFLK.EFN..N..KTICDSSVSPHDLKVKYLSTMETL....................................................
A0A091PZE8_LEPDC/147-277             .............TPILDADSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAVKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTIGDSSVSPRDLKVKYLSTMETL....................................................
W5PZ17_SHEEP/126-223                 .............SAILDLPVLEHLFAQ.HRHD...LVSGR.LRVGLSLKEQG------....E..CLSLAVLDLARMALEEAQ..RPEEL.LKTV...S.........Y.KVCLPPGLRDLIQGLSFVTRRRIRRTVRRAF-.---..-..------------------------rv..................................................
JAK2_RAT/142-261                     ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAV.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A096P1L9_PAPAN/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A226PM45_COLVI/170-289             .............SPVLDDLVMSYLFAQ.WRDD...FLGGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAV.YNSV...S.........Y.KMFLPKCVRAKIQEYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A226MI72_COLVI/130-249             .............SPVLDYPVIDYLFAQ.SRSD...FIAGR.MELALSLAGQE------....E..CLSLAVLDMLRIAKEKWQ..SPEQV.FSCI...S.........Y.KSCIPEPLRCRIQQHSFLTRKRIRRRVAQSLR.RMG..-..----GCRADGHCLKLKYLLDLERL....................................................
H2TCV4_TAKRU/145-264                 .............SPVLDHSGIAYLFAQ.LRSD...FTTGE.AGLSPPLTNQD------....E..CLGLAVLDLWRLAKEKRQ..SVKDL.CKSV...S.........Y.KSCLPKSHRADIEKRNWVERYRIRNTLKHFLK.KIG..-..----NCPVDDCNLKLMYLTEL---agi.................................................
A0A093FE34_GAVST/67-179              .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAGL-------EKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A1S3S4Y6_SALSA/134-264             .............SPLLEMTSLEYLFCQ.AKFD...FVNDV.TPMEDAQGKEELSRFKN....E..SLGMAVLHLSHQALCSGC..TLQEV.AKSV...S.........F.LRCIPRSFSKHIARDNFLTKIRIRRVFADFVR.TFQ..E..HTVDLGRLGSQEVMYKYLSTLEHL....................................................
A0A2K5IHF1_COLAP/147-277             .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
G3T029_LOXAF/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVCGW.IKLPVTHETQE------....E..CLGLAVLDMMRIAKEKGQ..TPLAI.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLEAL....................................................
A0A0A0MVD8_PAPAN/149-268             .............SALLDLPVLEHLFAQ.HRSD...LVSGR.LAVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
S7PNQ5_MYOBR/198-270                 .............SAILDLPVLEYLFAQ.HRND...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMACEQAQ..QPEDL.LKTV...R.........-.--------------------------------.---..-..------------------------qatlrplny...........................................
A0A0F8AN50_LARCR/130-249             .............SPVLDYSVIDYLFAQ.LRSD...FIASE.AGVSPPLSAQE------....E..CLNLAVLDLWRMAKERHQ..SVKEL.FKTV...S.........Y.KSCLPKSHRHDIQKRNRLDRYRIRSNMKVLLK.KLG..-..----NCSVDECSLKLMYLIEL---agi.................................................
G1P9Z2_MYOLU/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMIKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
V8NXT0_OPHHA/122-252                 .............SGILDKSSFAYLFEQ.GKYD...FINDI.ASLKDLHTEQEIHQFKN....E..SLGMAVLHLCHLALKKGI..SLEEV.AEKI...S.........F.KECIPRSFCQQIQQNNSLTKFRMKNVFKKFLQ.YFQ..Q..HTLSTGKLTEQDLMHKYLATLENL....................................................
F1NMJ9_CHICK/147-277                 .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
A0A1A6HG24_NEOLE/85-197              ......shifsve--------------D.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLAQMAREQSQ..RAGEL.LKTV...S.........Y.KTCLPPGLRDLIQGLSFVTRRRIRRTVLQALR.RVV..-..----ACQADRYSLMAKYILDLERL....................................................
G1TCI4_RABIT/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAI.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A2I4CIS6_9TELE/131-261             .............SPLLDITSLEYLFAQ.AKYE...FVNEV.AQMEDIESEEELSRFKN....E..SLGMAVLHLSHLAIQKNS..TLQEV.AKKH...S.........F.LECIPVSFAQHISRDNFLTKIRIRRVFSDFVR.TFQ..Q..HTVDIGHLGAQEIMYKYISTLEHL....................................................
A0A2D0PZ34_ICTPU/133-263             ............a-PLLEITSLEYLFAQ.AKCD...FVNDV.ISLEDVTDETELSGFKN....E..SLGMAVLHLSHKALQNGT..SLQEV.ARQT...S.........F.LRCIPRSFSRHISRDNYLTKLRIRRVFAKFVR.SFQ..Q..HTVGQGKLGAQEIMYKYLSTLERL....................................................
A0A0A0MUA2_PAPAN/141-266             ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRRGV..PLEEV.AKKT...S.........F.KDCIPLSFRRQIRQHSALTRLRLRNVFRRFLQ.DFQ..-..----PDRLSQQMVMVKYLATLERL....................................................
H2TE42_TAKRU/93-220                  ...........ls--LFDVRSLDYLFSQ.AKYE...FVNKI.VHMEDMKTEEEISSFKN....E..SLGMAVLHMSHR---LNI..ALTGK.SFSL...S.........Y.LDCIPKCFAKHISKDNFLTKIRIRRVFADFVQ.TFQ..E..HTVENGRLDTQKIMYKYISTLERL....................................................
A0A2K5H7M5_COLAP/126-245             .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
J9P349_CANLF/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
H0V6S7_CAVPO/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMRNM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
H0X486_OTOGA/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
H2R074_PANTR/126-245                 .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LPMGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
H2QWZ4_PANTR/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
L5L7Y5_PTEAL/126-245                 .............SAILDLPVLEHLFAQ.HRND...LVSGR.FHVGLGLKEQG------....E..CLSLAVLDLARMAREQAQ..RPEEL.LKTV...S.........Y.KACLPPGLRNLIQGLSFVTRRRIRRTVRQALC.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
F1QPM9_DANRE/134-253                 .............SPVLDDYVMSYLFAQ.WRSD...FVNGW.VKLSGSHENQE------....E..CLGMAVLDMMRTAKEKDC..SPLDI.YNDI...S.........Y.KSFLPKDMRERIQDYHFVTRKRIRYRFRKVVQ.QLS..-..----QCRATARDLKLKYLISLESL....................................................
A0A091DCH8_FUKDA/142-267             ............v-QILDPASFEYLFEQ.GKHD...FVNDV.VSLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCRSV..PLEEV.AKEI...S.........F.TRCIPRSFRQQIRQYNVLTQLRLRIAFHHFLR.TFQ..-..----PNHLSQQVVMVKYLATLERL....................................................
G3PKV8_GASAC/130-260                 .............SPLFEITSLEYLFFQ.AKYE...FVNEM.VQMEDVQSEEEGSRLKN....E..SLGMAVLQLSHQAMLTGC..TLQDA.ADKV...S.........F.LHCIPRSFAKQISKDNFLTKLRIRRVFREFVR.TFQ..Q..HTVDKGRLGAQEIMYRYIATLEHL....................................................
A0A2K5L5N3_CERAT/140-259             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
M7B3B8_CHEMY/158-288                 .............TPILDANSLEYLFAQ.GQYD...LVKCL.APVRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNM..KLPEL.PKDI...S.........Y.KRYIPETLNKTIRQRNILTRIRINNVFKDFLK.EFN..N..KTICDSSVSPHDLKVKYLSTMETL....................................................
H2TE39_TAKRU/134-264                 ...........ls--LFDVRSLDYLFSQ.AKYE...FVNKI.VHMEDMKTEEEISSFKN....E..SLGMAVLHMSHQALQTGS..TLQEV.AKKH...S.........Y.LDCIPKCFAKHISKDNFLTKIRIRRVFADFVQ.TFQ..E..HTVENGRLDTQKIMYKYISTLERL....................................................
A0A1S2ZMB9_ERIEU/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRLAKEKDQ..TPLDI.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIR.QFG..-..----QCKATARNLKLKYVINLEAL....................................................
E1BEL4_BOVIN/126-245                 .............SAILDLPVLEHLFAQ.HRHD...LVSGR.LRVGLSLKEQG------....E..CLSLAVLDLARMALEQAQ..RPEEL.LKTV...S.........Y.KVCLPPGLRDLIQGLSFVTRRRIRRTVCRALR.GVA..-..----TCQADRHSLMVKYIMDLERL....................................................
A0A093PY01_9PASS/141-260             .............SPVLDDLVMSYLFAQ.WRAD...FLEGW.VQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDE..TPLAI.YNSV...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
E9QJS1_MOUSE/172-292                 ....sfsihrstp--------------Q.GKHE...FMNDV.VSLRDLSSEEEIHHFKN....E..SLGMAFLHLCHLALSRGV..PLEEM.AREI...S.........F.KNCIPHSFRQHIRQHNVLTRLRLHRVFRRFLR.AFR..-..----PGHLSQQVVMVKYLATLERL....................................................
A0A091P2W8_APAVI/141-260             .............SPVLDDFVMSYLFAQ.WRDD...FLDGW.VQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLENL....................................................
H3B0L6_LATCH/131-251                 .............SAVLDYSVIDYLFAQqSRSD...FISGR.TRTTLSLQTQE------....D..CLGMAMLDMMRIAKERNK..RVKEV.FRYV...S.........Y.KSCIPENLRNEIQQHNFLTRKRIRRKFQKSLK.KIS..-..----QCKTDDCCLKLKYLIDLEEL....................................................
A0A096P1M0_PAPAN/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
F6RE38_HORSE/141-260                 ............a-PLLDDFVMSYLFAQ.WRHD...FLHGW.VKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLTI.YSSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
JAK2_CHICK/140-259                   .............SPVLDDLVMSYLFAQ.WRKD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAV.YNSV...S.........Y.KMFLPKCVRAKIQEYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A093F367_TYTAL/141-260             .............SPVLDDHVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A1U7STL7_TARSY/141-260             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRARIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A093GHG5_DRYPU/147-277             .............TPIFDASSLEYIFAQ.GQYD...LVKGL.ALIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAMKKKV..KLPEL.SKEI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICEGNVSPRDLKVKYLSTMETL....................................................
D2HMR9_AILME/67-186                  ............a-PLLDDFVMAYLFAQ.WRHD...FLHGW.IKIPVTHETQE------....E..CLGMAVLDMMRLAKEKDQ..TPLDI.YSSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
F1S818_PIG/147-277                   .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
M7B4M9_CHEMY/226-345                 .............SPVVDDLVMSYLFAQ.WRDD...FVHGW.VKVPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLESL....................................................
H3ABD2_LATCH/138-257                 .............SPVFDDAVMSYLFAQ.WRDD...FVNAW.AKMSVTHETQE------....E..CLGMAVLDMMRMAKEKDQ..SPISI.YNSI...S.........Y.KTLLPKSVRARIEDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKASARDLKLKYIINLET-f...................................................
B4MCY4_DROVI/127-235                 ............l-PVIDVHCHKYLYHQ.MRYD...MLHEQiAEIRYPEQRD-------....K..VMGLAVMDMVID-REEQL..LLAQ-.AVEK...A.........Y.KSYLPRSLWR---AHRIFVRSKIRSTFRR---.---..-..------------------------lnsnrpnvdslkwhyvhqic................................
A0A287A292_PIG/141-266               ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFQN....E..SLGMAFLHLCQLALRHGV..PLEKV.AKKI...S.........F.KDCIPRSFRRQIRQHNALTRLRLRSIFRKFLR.AFQ..-..----PGCLSQQVVMVKYLATLERL....................................................
K1R7D2_CRAGI/67-180                  .........palg-----PEILKYLYLQ.CKDD...FVKSR.LS--DI-YEQ---DIKN....EakARGYAVLSIVIASKMEEK..DCQDI.LNKQ...K.........L.EAFLPSHLVVRLWRGYQL-RKNMKTKTEEFLA.QHS..N..TKVEE-------------------llmgyikd............................................
A0A1L8H2U7_XENLA/138-268             ............g-AILDLASFEYLFEQ.GKFD...FVNDV.VSLKDFPMEQDIHRFKN....E..SLGMAVLHLSHIAIKKKV..SLEEV.AKQI...S.........F.KECIPKSFCRQIQQNNYLTKFRMKNVFKKFVR.RFH..L..HTVSPGKLTEEDIMYKYLSTLENL....................................................
F6WC83_HORSE/142-267                 ............m-QLLDSASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PVEKV.AKKI...R.........W.MEM-----------------------------.---..-..------------------------tehlgprvdlaycrafihsrdrqstkykskrfirqflteqvtfkckdlkevk
G1M9G8_AILME/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A1V4KQA1_PATFA/173-292             .............SPILDYPVIDYLFAQ.SRSD...FIGGR.VAVALSLPTQE------....E..CLSLAVLDMLRIAKEEQQ..SPGQV.FSYV...S.........Y.KSCIPAPLRFQIQQHNFLTRKRIRRRFSKSLR.KIG..-..----GCQTDGRYLKLKYLLDLERL....................................................
A0A091TPR4_9AVES/141-260             .............SPVLDDVVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQGYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A0G2K636_RAT/126-244               .............SAILDVHVLEHLFAQ.HRSD...LVSGR.LPVGLSLKDQG------....E..FLSLAVLDLAQMARKQAQ..RPGEL.LKSV...S.........Y.KACLPPSLRDLIQGQSFVTRRRIRRTVVQALP.CSS..-..-----LPSRPYALMAKYILDLERL....................................................
A0A091GZ50_9AVES/140-259             .............SPVLDDLVMSYLFAQ.WRAD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSI...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
F1R5C7_DANRE/145-275                 .............TPLLDAASLDYLFAQ.GQYD...FLRGL.SPVRPTQNDEEHHEIEN....E..CLGMAVLAITHHAKSNNL..PLSGA.GAET...S.........Y.KRFIPDSLNRTIKQRNFLTRIRISNVFKNFLN.EFN..S..KTIQDSNIGLYDLKVKYLSTLETL....................................................
A0A1L8HY58_XENLA/140-259             .............SPVLDDIVMAYLFAQ.WRDD...FVNGR.ISVPITHEAQE------....E..CLGMAVLDMMRMASEKGQ..SPLAV.YNSV...S.........Y.KKFLPKCIRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCQATARDLKLKYLINLETL....................................................
A0A1S3WAF8_ERIEU/147-277             .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMIKKV..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
F1PBD0_CANLF/146-273                 ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWDLSSEEEIHHFKN....E..SLGMAFLHLCHLALSHGI..PLEKV.AKKIrppS.........F.KDCIPRS-RLQIRRHNALTRLRLRSIFRRFVR.AFQ..-..----PGHISQQVIMVKYLATLEQL....................................................
M3Y5N7_MUSPF/142-267                 ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSGEEEIRHFKN....E..SLGMAFLHLCHLALCRGV..PLEKV.AKKI...S.........F.KDCIPRSFRLQIRRHNALTRLRLRNIFRRFVR.AFQ..-..----PGHVSQQVVMVKYLATLEQL....................................................
K7GSE8_PIG/126-245                   .............SAILDLPVLEHLFAQ.HRND...LVSGR.LPVGLGLKEQG------....E..CLSLAVLDLARMALEKAQ..RPEEL.LKIV...S.........Y.KVCLPPALRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
A0A2I4CI85_9TELE/49-168              .............SPILDDYVMSYLFSQ.WRND...FVNGF.VKISDSHETQE------....E..CLGLAVLDMTRTAKEKQL..PPLDI.YHSI...S.........Y.KSFLPKDMRAQIQDCSFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISIESL....................................................
H2VE41_TAKRU/141-267                 .............TPLLDAASLDYLFYQ.GQHS...FHKGL.VPLRKSHSDAEQHEIEN....E..CLGMAVLAITHT---TNM..SVPG-.SHDI...S.........Y.KRFIPESLNRSIKQRSFMTRIRINNVFKKFLS.EFH..Q..RTIRDSNITPYDLKIKYLATLEGL....................................................
G3VR92_SARHA/126-245                 ............n-AILDLPVLKYLFAQ.SRSD...FINGR.MNLTLNLKEQG------....E..CLSLAVLDLTRMAQEQGI..RPKEI.LRRI...S.........Y.KTCIPGSFRRLIQSLSFMTRKRYRQMVSRALQ.SVA..-..----SCQADVYSIMLKYLMDLERL....................................................
F1QWX8_DANRE/119-238                 ............a-PVCDDITTAYLCAQ.WRSD...FLSGA.VSVPVSLEFQE------....E..CLGLAVLDIMRLAKEKGK..SPVDI.YNHS...S.........Y.KSFLPKNMREHIQNQHLVTRKRIRFRFRRFLQ.QFG..-..----SCKAAPRELKLKYVVSLETL....................................................
H2VE43_TAKRU/127-253                 .............TPLLDAASLDYLFYQ.GQHS...FHKGL.VPLRKSHSDAEQHEIEN....E..CLGMAVLAITHT---TNM..SVPG-.SHDI...S.........Y.KRFIPESLNRSIKQRSFMTRIRINNVFKKFLS.EFH..Q..RTIRDSNITPYDLKIKYLATLEGL....................................................
JAK2_PIG/142-261                     ............a-PLLDDFVMSYLFAQ.WRHD...FLYGW.VKIPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLDI.YSSV...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
A0A096MF50_POEFO/142-261             ............s-LVLDYNVIDYLFAQ.LRSD...FIASE.AGIVPPLSAQE------....E..CLGLAVLDLWRMAKERRQ..TIREL.CKTV...S.........Y.KSCLPKSHRHEIQKRNRLDRFRIRNTLKRFLK.KLG..-..----KCSVDEYSLKLKYLIEL---agi.................................................
A0A093HE63_STRCA/141-260             .............SPVLDDIVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A226N5B7_CALSU/245-304             .............---------------.----...-----.-----------------....-..------------------..-----.-KRI...S.........Y.KMFLPKCVRAKIQEYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
M3WBF6_FELCA/142-267                 ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.APLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCHGI..PLEKV.AKKI...S.........F.KDCIPRSFRLQLRRHNALTRLRLRRLFRRFVR.AFQ..-..----PGHVSQPVIMVKYLATLEQL....................................................
H2M2I1_ORYLA/144-274                 .............TPLFDGGSLDYLFEQ.AKHD...FKMGM.VPLRNVQSETEQHEIEN....E..CLGMAVLAITHNALATNT..PMSTI.YRDY...S.........Y.KDFIPESLNRNIKQRNILTRVRINNVFKKFLC.DFN..N..GTVQESNITTYDLKIKYLATLEGL....................................................
L8YCU2_TUPCH/155-213                 ...........eq---------------.----...-----.-----------------....-..------------------..-----.----...V.........F.KDCIPRSFRRQIQQHNALTRLRLRSVFRKFLR.SFQ..-..----PTCLSQQVVMVKYLATLERL....................................................
A0A2I3SYV7_PANTR/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A091TQI1_PHALP/141-260             .............SPVLDDVVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
I3N6E8_ICTTR/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKV..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSPHDLKVKYLATLETL....................................................
A0A218U7X2_9PASE/133-252             .............SPVLDYPVIDYLFAQ.SRSD...FIGGR.VAVGLSLPTQE------....Q..CLSLAVLDMLRIAKEQRQ..SPAQV.CSHV...S.........Y.KSCLPAPLRSQIQQHNFVTRKRLRRRFGKSLR.RLG..-..----GCHTDGPQLKLKYLLDLERL....................................................
A0A096LUR2_POEFO/129-259             .............TPLLDVGSLEYLYFQ.CQHD...FQTGK.APLRAAQSEAEQHEIEN....E..CLGMAVLAITHYAKDIGI..PFSAA.SREM...S.........Y.KRFIPESLNSIIKQRNILTRIRISNVFKKFLA.EFN..T..QTVGESNITCYDLKIKYLATMEGL....................................................
G1P7K0_MYOLU/23-142                  .............SAILDLPVLEYLFAQ.HRND...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMACEQAQ..QPEDL.LKTV...S.........Y.KTCLPPGLRDLIQGLSFVTRRRIRRRVRQALL.RVA..-..----TCQADRHSLMAKYIMDLERL....................................................
A0A093QCV4_9PASS/146-276             .............TPILDGFSLEYIFAQ.GQYD...LVKGL.APIRDPRNEQEVHEIEN....E..CLGMAVLAISHYAINKKV..KLPEL.PKDI...S.........Y.KQYIPESLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSARDLKVKYLSTMETL....................................................
A0A093CU52_TAUER/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLNGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A2G9RUE2_LITCT/1-81                .............---------------.----...-----.-----------------....-..---MAVLDMMRIASEKEQ..SPIAI.YNAV...S.........Y.KKFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARDLKLKYLINLETL....................................................
H2R6D4_PANTR/141-266                 ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRHGI..PLQEV.AKKT...S.........F.KDCIPRSFRRHIRQHSALTRLRLRNVFRRFLR.DFQ..-..----PGRLSQQMVMVKYLATLERL....................................................
G7PZ76_MACFA/141-266                 ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PLEEV.AKKT...S.........F.KDCIPLSFRRQIRQHSALTRLRLRNVFRRFLQ.DFQ..-..----PDRLSQQMVMVKYLATLERL....................................................
S9X5J1_CAMFR/263-393                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMIKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A091I5H9_CALAN/141-260             .............SPVLDDVVMSYLFAQ.WRDD...FLDGW.IHMPVTHETQE------....E..CLGMAVLDIMRVAKEKDQ..TALAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A091EJU9_CORBR/140-259             .............SPVLDDLVMSYLFAQ.WRAD...FLDGW.VQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPMAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
G1PKC8_MYOLU/146-271                 ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PLEKV.AKKT...S.........F.KDCIPRSFRQQIRQYNAFTRLRLRIIFRRFLH.AFQ..-..----PDSLSQHVVMVKYLATLERL....................................................
A0A226F4F6_FOLCA/111-222             ...........nr---LDENAFDYTFHQ.IRHD...LLQGH.IP--DIS--QD--QVKS....E..ALGLCVTDMLRLIQEEAM..TLDYI.--EA...N.........Y.KQFIPKSIYR---QHKFFLKKKIHDTLVKLVE.RSR..-..------PQNSNYIKEQYISQVEEL....................................................
A0A151ML25_ALLMI/146-209             .............SAVLDQPVIDYLFAQ.SRSD...FLRGL.VAGVLSWQTLE------....A..CLCLAVLDMLRIAKERRQ..SLDHV.FS--...-.........-.--------------------------------.---..-..------------------------cvr.................................................
F6TJE9_HORSE/145-216                 ............m-QLLDSASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PVEKV.AKKI...-.........-.--------------------------------.---..-..------------------------rcl.................................................
A0A087XSD4_POEFO/144-263             .............SPVLDDYVMSYLFSQ.WRND...FVNGV.VTISNSHESQE------....E..CLGMAVLDMTRTAKERQM..SPLDI.YHNT...S.........Y.KSFLPKDMRNQIQDCSFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISIESL....................................................
S5RRC4_SALSA/134-264                 .............SPLLEMTSLEYLFCQ.AKFD...FVNDV.TPMEDAQGKEELSRFKN....E..SLGMAVLHLSHQALRSGC..TLQEV.AKSV...S.........F.LRCIPRSFAKHIARDNFLTKIRIRRVFADFVR.TFQ..E..HTVDVGRLGSQEVMYKYLSTLEHL....................................................
F6WH53_MONDO/140-259                 .............TPLLDDFVMSYLFAQ.WRED...FVHGW.IKVPVTHETQE------....E..CLGMAVLDIMRIAKENDQ..TPLAV.YNST...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A1S3LTU5_SALSA/1-81                .............---------------.----...-----.-----------------....-..---MAVLDMMRMAKESSQ..SPVDI.YNDT...S.........Y.KSFLPKNMRAHIQEYHFVTRKRIRHRFRKFIQ.QFS..-..----QCKATARDLKLKYLVNLETL....................................................
A0A1S3KQH9_SALSA/175-294             .............SPVLDDTVMSYLFAQ.WRSD...FVDGW.VSIPVNHEAQE------....E..CLGMAVLDMMRMAKESSQ..APVDI.FNDT...S.........Y.KSFLPKDIRARIQEYHFVTRKRIRHRFKKFIQ.QFC..-..----QCNATARDLKLKYLANLEML....................................................
A0A091FRB5_CORBR/95-221              ............g-ALLDRSSFEYLFEQ.GKFE...FINDV.ASLKDFQSEPEIQRFKN....E..SLGMAVLHLSHIAIKKGI..SLEEV.ARKY...S.........F.KDCIPRSFRRQIQQNNFLTRFRMKNVFRRFLR.HFQ..R..HTVAAGKLSERDVMYKH-------pkt.................................................
A0A226PRN9_COLVI/255-385             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
W5PVH1_SHEEP/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FLHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKNQ..TPLDI.YSSI...S.........Y.KTFLPKCVRAKIQEYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
A0A1U7QD80_MESAU/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAV.YNSV...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
H3DMJ5_TETNG/1-92                    .............---------------.----...-----.----------------N....E..SLGMALLHMSHQALQTWL..HTSSVlCFSL...S.........Y.LDCIPKCFAKHIAKDNFLTKVRIQRMFADSVR.TFQ..E..HTVDKGRLGMQKTMFKYISTLERL....................................................
A0A2I2V2G4_FELCA/126-245             .............SAILDLPVLEHLFAQ.HRND...LVSGR.LAVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..QPEEL.LKTV...S.........Y.KACLPPDLRDLIQGLSFVTRKRIRRTVRRALG.RVT..-..----ACQADRHSLMAKYIMDLERL....................................................
A0A1S3LVA6_SALSA/145-275             .............TALLEAASLKYLFAQ.GQHD...FLKGR.AAVRNSQNEEEAHCIEN....E..CLGVAVLSITHNALEKNI..SNPYL.GGQI...S.........Y.KKYIPESVNQIIKQRNFLTRVRISRVFQHFLN.EFN..N..KTVKNNKVNTHDIKVKYLATLETL....................................................
K7FRF6_PELSI/170-300                 .............TPILDANSLEYLFAQ.GQYD...LVKCL.APVRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNM..KLPEL.PKDI...S.........Y.KRYIPETLNKTIRQRNILTRIRINNVFKDFLK.EFN..N..KTICDSSVSPHDLKVKYLSTMETL....................................................
M3ZWG4_XIPMA/133-252                 ............s-LVLDYNVIDYLFAQ.LRSD...FIASE.AGIVPPLSAQE------....E..CLGLAVLDLWRMAKERRQ..TIREL.CKTV...S.........Y.KSCLPKSHRHEIQKRNRLDRFRIRNTLKRFLK.KLG..-..----KCSVDEYSLKLKYLIEL---agi.................................................
A0A0P7WCB5_9TELE/141-249             .........qita---------------.SRSD...FVNGH.AGVSPSLSAKE------....E..CLGMAVLDLWRQAKECNQ..SLKEV.CKKV...S.........Y.KSCLPESHRQDIQQLNRLARYRIRKTLKHFLN.KLG..-..----RCPAVGYSLKLKYLMEL---agv.................................................
F1S3L9_PIG/141-266                   ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFQN....E..SLGMAFLHLCQLALRHGV..PLEKV.AKKI...S.........F.KDCIPRSFRRQIRQHNALTRLRLRSIFRKFLR.AFQ..-..----PGCLSQQVVMVKYLATLERL....................................................
A0A091L3K5_CATAU/38-168              .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
A0A2K5H7P1_COLAP/126-245             .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
A0A2K5JYV7_COLAP/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
I3IZB2_ORENI/163-290                 .....fyshnvlv-----------LTNQ.AKYE...FVNEV.VQIEDVKTEEEQTRFKN....E..SLGMAVLHLSYQAIQTQS..TLQDV.ASKV...S.........F.LDCVPRSFAKHISRDNFLTKLRIQRVFKDFVR.SFQ..Q..HTVDRGKLCTEEIMYKYIATLEHL....................................................
A0A0D9R8Z9_CHLSB/140-259             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
G5B225_HETGA/142-267                 ............v-QVLDPASFEYLFEQ.GKYE...FVNDV.VSLRELSSEEEIHHFKN....E..SLGMAFLHLCHLALCRSV..PLEEV.AKEI...S.........F.TRCIPRSFRQQIRQYNMLTRLRLRSVFRRFLH.AFQ..-..----PNHLSQQVVMVKYLATLEHL....................................................
G3H6C9_CRIGR/142-267                 ............v-HLLDSASFEYLFEQ.GKYE...FMNDV.VSLRDLSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PLEEM.AREI...S.........F.KKCIPRSFRQHIRQHNALTRLRLRRVFRRFLR.AFQ..-..----PGHLSQQVVMVKYLATLERL....................................................
F6YLX1_MACMU/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A1S3PI02_SALSA/144-263             .............SPVLDDFVMAYLFAQ.WRSD...FVNGW.VKIANTHETQE------....E..CLGMAVLDMMRIAKERQM..SPLDI.YNSI...S.........Y.KSFLPKDMRAHIQDCNFVTRKRIRYRFKKFIQ.QFS..-..----QCRATARDLKLKYLINMESL....................................................
A0A093QW73_PHACA/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
H2SBF4_TAKRU/1-48                    .............---------------.----...-----.-----------------....-..------------------..-----.----...-.........-.-------MQDRIQEYNMLTRKRIRYRFCKFIQ.HFS..-..----ECKATVANLKLKYLMSLEML....................................................
A0A1U8DSZ3_ALLSI/128-247             .............STVLDQPVIDYLFAQ.SRSD...FLRGL.VAGALSWQTLE------....A..CLCLAVLDMLRIAKERRQ..SLDRV.FSCV...S.........Y.KSCLPEGLRDQIQQRGFLTRKRIRRKFGQSLR.RLG..-..----ACQTDARYLKIKYLLDLARL....................................................
A0A2I4BPV4_9TELE/143-273             ............a-PLLDIGSLDYLFAQ.AQHD...FQTGK.VPLRKAQSDSEQHEIEN....E..CLGMAVLAITHYAMFKKI..PLPTV.TREI...S.........Y.KRFIPESLNSEIRQRNILTRIRINNVFKKFLS.EFN..D..NTVKKSQIRCYDLKIKYLATLEGL....................................................
M7AIF3_CHEMY/73-192                  .............SAVLDCPTMNYLFAQ.SRSD...FISGR.MEGALSLQMQE------....E..CLSLAVLDMLRMVKERKW..SLEEI.FNSV...S.........Y.KSCIPETLRHQIQQQSFLTRKRIRRKFHKSLR.KIS..-..----GCQTDDCTLKLKYLIDLEKL....................................................
H2VE42_TAKRU/131-257                 .............TPLLDAASLDYLFYQ.GQHS...FHKGL.VPLRKSHSDAEQHEIEN....E..CLGMAVLAITHT---TNM..SVPG-.SHDI...S.........Y.KRFIPESLNRSIKQRSFMTRIRINNVFKKFLS.EFH..Q..RTIRDSNITPYDLKIKYLATLEGL....................................................
G3WN84_SARHA/147-277                 .............TPLLDANSLEYLFAQ.GQYD...LVKCL.APVRDPKTDQEVHEIEN....E..CLGMAVLAISHYAMMNNI..QLPDL.PKDV...S.........Y.KRYIPETLNKTIRQRNLLTRLRINNVFKDFLK.EFN..N..KTICDSSVTPHDLKVKYLSTLETL....................................................
A0A2K5KJN2_CERAT/141-266             ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRRGV..PLEEV.AKKT...S.........F.KDCIPLSFRRQIRQHSALTRLRLRNVFRRFLQ.DFQ..-..----PDRLSQQMVMVKYLATLERL....................................................
G1KI54_ANOCA/147-277                 .............TPLLDAFSLEYLFAQ.GQND...LVRCF.APVRDSKNDQETQEIQN....E..CLGMAVLAITHYAIKKNL..RLPEL.LRDI...S.........Y.KRYIPESLNKTIKQKNLLTRIRINNVFKDFLK.EFN..K..RTICDSSVSPHDLKVKYLSTMETL....................................................
A0A091KC07_COLST/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLEGW.VQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSI...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
W4Z1N2_STRPU/114-214                 ...........fm--LLEENVVNYMFCQ.YRES...FLNDE.F----MGLSTE------....E..SLGLMVLDFMQHVKEDGT..SLTNL.NGRL...R.........F.GRFLPKSLNEGL---SWWDKRKLRRKVRTALT.DFR..-..------------------------ddpretfa............................................
A0A091W206_NIPNI/95-225              ............g-ALLDKSSFEYLFEQ.GKFE...FINDV.ASLKDLQTEQEIQRFKN....E..SLGMAVLHLSHIAIKKGI..SLEEV.ARKY...S.........F.KDCIPRSFYRQIQQNNYLTKFRMKNVFKKFVQ.RFQ..R..HTVSTGKLTVQDIMYKYLATLEHL....................................................
W5L4R3_ASTMX/135-254                 .............SPVLDDHVMAYLFAQ.WRSD...FVNGW.VKLSSNHETQE------....E..CLGMAVLDMMRIAKEKQR..SPLDI.YNAM...S.........Y.KSFLPKDMRKQIQDYHLVTRKRIRYRFRKVVQ.QFS..-..----QCRATARDLKLKYLINLEAL....................................................
L9KPJ3_TUPCH/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVQGW.IKIPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAI.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
I3J7Z7_ORENI/157-276                 .............SPVMDDCVMAYQFFQ.WRSD...FLNGW.VDIPVSHEAQE------....E..CLGMAVLDMMRLAKERGQ..SAVDI.YNDK...S.........Y.KSFLPVSMRSRIQEYNILTRKRIRYRFRKFIQ.QFS..-..----ECKATVCNLKLKYLMSLEML....................................................
JAK1_MOUSE/147-275                   .............TPLLDASSLEYLFAQ.GQYD...LIKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSV--HDLKVKYLATLET-s...................................................
A0A1U7R5X2_MESAU/147-277             .............TPLLDASSLEYLFAQ.GQYD...LIKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRLRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A1D5PS66_CHICK/130-249             .............SPVLDYPVIDYLFAQ.SRSD...FIAGR.MELALSLAGQE------....E..CLSLAVLDMLRIAKEKWQ..SPKEV.FSCV...S.........Y.KSCIPEQLRCQIQQHSFLTRKRIRRRVAQSLR.RMG..-..----GCRVDGCCLKLKYLLDLERL....................................................
F7EV03_XENTR/131-250                 ............d-PLLSYPVIDYLFAQ.CRSD...FLSDR.MKLPTSLDMQD------....Q..CLTLAVLDMMRLTQENNK..PPKQI.LSMI...S.........Y.KQCVPQSLRQAIQKLSFFSRKRLRSRVQHSLR.KIR..-..----ACTLTDPLIKLKYLVDLEKL....................................................
L9L1A5_TUPCH/126-228                 .............SAVVDLPVLEHLFAQ.HRSD...LVSGR.LPVGLGLKEQG------....E..CLSLAVLDLARMALEQAQ..RPAEL.LKTV...S.........Y.KACLPPGLRALIEGLSFVTRKRIRRT------.---..-..------------------------afqpfgdfpeil........................................
A0A1U8DCB6_ALLSI/159-289             .............SALLDRASFEYLFEQ.GKFE...FVNDV.ASLQDLATEQDLHRFKN....E..SLGMAVLHLSHLALRRGL..SLEEA.AKKC...S.........F.KDCIPWSFRRQIQQSSSLTRLRLRSVFRRFVQ.HFQ..R..HTVGAGRLTEQGVMYKYLATLESL....................................................
A0A1L8HXG0_XENLA/131-250             ............d-PLLSYPVIDYLFAQ.CRSD...FLNDR.MHLPTSLDMQD------....Q..CLALAVLDMMRLTQENNK..TPKEI.LSMI...S.........Y.KQCVPQSLRQAIQQLSFLSRKRLRSRVQHSLR.KIR..-..----ACTLTVPLIKLKYLVDLEKL....................................................
A0A087XMA3_POEFO/132-259             .............SPLLDITSLEYLFAQ.AKHE...FVNN-.--VEEPKSDEESNRFKN....E..SLGMAVLHLSHLAMQKGL..NLQDV.AGKT...G.........F.QNCIPRTFAENISRDNFLTKIRIRRVFTEFVQ.TFQ..Q..HTVDKGQLGAHEIMYKYISTLENL....................................................
A0A2K5ITF8_COLAP/141-266             ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRRGV..PLEEV.AKKT...S.........F.KDCIPLSFRRQIRQHSALTRLRLRNVFRRFLQ.DFQ..-..----PDRLSQQMVMVKYLATLERL....................................................
A0A1S3QZS8_SALSA/137-267             ............n-PLLDTASLKYLFAQ.GQHD...FVKGW.ATLRNPQNEEEVHYIEN....E..CLGMAVLSISHHALDNNI..VIPGV.AGQI...S.........Y.KKYIPDRVNQIIKQRNFLTRLRISRVFQDFLN.DFN..N..KTVQSDNVSTHDIKVKYLATLETL....................................................
A0A091GBI7_9AVES/95-225              ............g-AVLDKSSFEYLFEQ.GKYE...FINDV.ASLKDLQTEQEIQRFKN....E..SLGMAVLHLSHMAIKKGI..SLEEV.TRKY...S.........F.KDCIPRSFYRQIQQNNHLTRFRMKNVFKKFVQ.RFQ..R..HTVNAGKLTAQDIMYKYLATLEHL....................................................
A0A226MBH8_CALSU/86-216              .............TAVLDRASFEYLFEQ.GKFD...FINDV.ASLTDFRTEAEVQRFKN....E..SLGMAVLHLAHIALRSGR..CLQDV.ARKY...S.........F.QECIPRSFRHQIQRNSAVTRFRMRNVFRRFVR.RFQ..Q..HTVGAGKLAEQDVMFKYVATLEQL....................................................
G1NGZ6_MELGA/147-277                 .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
H2VE39_TAKRU/150-276                 .............TPLLDAASLDYLFYQ.GQHS...FHKGL.VPLRKSHSDAEQHEIEN....E..CLGMAVLAITHT---TNM..SVPG-.SHDI...S.........Y.KRFIPESLNRSIKQRSFMTRIRINNVFKKFLS.EFH..Q..RTIRDSNITPYDLKIKYLATLEGL....................................................
A0A0D9S727_CHLSB/147-277             .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A1S3QZA5_SALSA/137-267             ............n-PLLDTASLKYLFAQ.GQHD...FVKGW.ATLRNPQNEEEVHYIEN....E..CLGMAVLSISHHALDNNI..VIPGV.AGQI...S.........Y.KKYIPDRVNQIIKQRNFLTRLRISRVFQDFLN.DFN..N..KTVQSDNVSTHDIKVKYLATLETL....................................................
A0A0R4ICU5_DANRE/134-253             .............SPVLDDYVMSYLFAQ.WRSD...FVNGW.VKLSGSHENQE------....E..CLGMAVLDMMRTAKEKDC..SPLDI.YNDI...S.........Y.KSFLPKDMRERIQDYHFVTRKRIRYRFRKVVQ.QLS..-..----QCRATARDLKLKYLISLESL....................................................
F1MCX4_BOVIN/142-267                 ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFQN....E..SLGMALLHLCHLALRNGV..PLEKV.AKKT...S.........F.KDCIPRSFRRQMRQHNALTRLRQRSIFRKFLR.AFQ..-..----PGCLSQQVVMVKYLATLERL....................................................
K1R7W9_CRAGI/201-315                 ..........lpa---LGLEILKYLYLQ.CKDD...FVKSR.LS--DI-YEQ---DIKN....EakARGYAVLSIVIASKMEEK..DCQDI.LNKQ...K.........L.EAFLPSHLVVRLWRGYQL-RKNMKTKTEEFLA.QHS..N..TKVEE-------------------llmgyikv............................................
H2L7P4_ORYLA/144-263                 .............SPVLDDSVMSYLFYQ.WRND...FVNGL.VKISNSHEMQE------....E..CLGMAVLDMTRTAKEKQT..SPLEI.YDTM...S.........Y.KSFLPKDIRAQIQDCSFLTRKRIRFRFKRFIQ.QFS..-..----HCRTTVWDLKLKYLISIESL....................................................
A0A151NJE5_ALLMI/147-277             .............SPILDGYSLEYLFAQ.GQHD...LVKGL.APVRDPKNDQEIHEIEN....E..CLGMAVLAISHFAINKNT..KLPDL.PKDI...S.........Y.KRYIPETLNKSIRQRNILTRIRINNVFKEFLK.EFN..N..KTICDSSVSPHDLKVKYLSTMETL....................................................
L5K6W6_PTEAL/154-284                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMIKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A1S3IPL9_LINUN/104-224             ............r----DLKAFHYYFLQ.CRHD...FVNDV.LKTRYGTTLST-----S....H..NLGLAVLDMFRVGVQNKM.tSADQV.LAKY...G.........Y.KIFLPPSSLGGF--NKLLDSVRLKKNFKDELD.KLFtdQ..SSIQAQNL--TSIKHRYLNGL---ft..................................................
A0A2D0PQM4_ICTPU/131-250             .............SPILDDHVMAYLFAQ.WRSD...FVNGW.VKLSTSHETQE------....E..CLGMAVLDMMRIAKEKQC..SPLDI.YNAI...S.........Y.KSFLPKDMRLKIQDYHFVTRKRIRYRFRKVVQ.QFS..-..----QCRATPRDLKLKYLINLEAL....................................................
G3US57_MELGA/1-57                    .............---------------.----...-----.-----------------....-..------------------..-----.----...S.........Y.KMFLPKCVRAKIQEYHILTRKRIRYRFRKFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A2I4AUZ4_9TELE/144-263             .............SPVMDDCVLSYLFAQ.WRSD...FLKTL.VEMPINHETQE------....E..CLGMAVLDIMRLAKEKDQ..SPVEV.YNTT...S.........Y.KSLLPQHVRHRIRAYNFFTRKRIRYRFKKFIQ.QFI..-..----ECKATVRNLKLKYLMSLEML....................................................
A0A091ULX3_NIPNI/141-260             .............SPVLDDVVMAYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQGYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
G1RYT5_NOMLE/146-276                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A096MCU2_POEFO/144-263             .............SPVLDDYVMSYLFSQ.WRND...FVNGV.VTISNSHESQE------....E..CLGMAVLDMTRTAKERQM..SPLDI.YHNT...S.........Y.KSFLPKDMRNQIQDCSFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISIESL....................................................
F1S936_PIG/126-245                   .............SAILDLPVLEHLFAQ.HRND...LVSGR.LPVGLGLKEQG------....E..CLSLAVLDLARMALEKAQ..RPEEL.LKIV...S.........Y.KVCLPPALRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
F7FSX3_ORNAN/59-178                  ............a-PLLDDYIMSYLFAQ.WRDD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAI.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A226MI46_CALSU/130-249             .............SPVLDYPVIDYLFAQ.SRSD...FIAGR.MELALSLAGQA------....E..CLSLAVLDMLRIAKEKWQ..SPEQV.FSCI...S.........Y.KSCIPEPLRCRIQQHSFLTRKRIRRRVAQSLR.RMG..-..----GCRADGHCLKLKYLLDLERL....................................................
A0A2I0MG33_COLLI/140-259             .............SPVLDDTVMCYLFAQ.WRDD...FLDGW.VQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
F7GS58_MACMU/113-221                 .............SAILDLPVLEHLFAQ.HRGD...LVSGR.LAVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKT-...-.........-.----P---ARLIQGPGFVTRRRFGGAVRQ---.-G-..-..RRVAACQADRHSLMAKYIMDLERL....................................................
F6X8E5_ORNAN/132-251                 .............SAILDFPVLDYLFAQ.ARSD...FVSGR.MEFSLSLKEQE------....E..CLSLAVLDLTQLAREKGQ..GPEEI.FKSV...S.........Y.KSCLPEKFRRQIQGLSFLTRKRIRKTVQQSLR.QVA..-..----GCQADGRSLKLKYLMDLERM....................................................
A0A1L8GFQ7_XENLA/133-209             .............TPLLDASSLDYLFAQ.GQYE...LVKCL.APVREPKNDQEVHEIEN....E..CLGMAVLAISHYAMKRNI..QLHDL.PKDI...-.........-.--------------------------------.---..-..------------------------glctasek............................................
I3KJT0_ORENI/144-263                 .............SPVIDDFVMSYLFFQ.WRND...YLNGL.VKISNSHETQE------....E..CLGLAVLDMTRTAKEKQL..SPLDI.YHSI...S.........Y.KSFLPKDMRAQIQDCNFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISMESL....................................................
H2V1W5_TAKRU/141-260                 .............SPVFDDYVMSYLFSQ.WRND...FVNGL.VKIPSSHESQE------....E..CLGMAVLDMTRTAKESQL..SPLDI.YHTM...S.........Y.KSFLPKEMRAQIQDCNFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISMESL....................................................
F1N0D6_BOVIN/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A226MYM3_COLVI/124-186             ............r---------------.----...-----.-----------------....-..------------------..-----.----...S.........F.QECIPRSFRHQIQRNSAVTRFRMRNVFRRFVR.RFQ..Q..HTVGAGKLAEQDVMFKYVATLEQL....................................................
A0A2I3LH42_PAPAN/18-91               ...ymkkrctfll---------------.----...-----.-----------------....-..------------------..-----.--SF...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
JAK2_MOUSE/142-261                   ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAV.YNSV...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A1S3P9N7_SALSA/144-274             .............TPLLDSASLDYLFFQ.GQND...FQKGL.AVVRSQQSEAEQHEIEN....E..CLGMAVLAITHYAMTKEI..PLSTT.SNEI...S.........Y.KRFIPESLNRSIKQRNILTRLRINNVFKNFLN.EFN..S..RTMLESNITLYDLKIKYLSTLEGL....................................................
W5LHR3_ASTMX/138-268                 .............TAVLDLPSLTYLYAQ.SQYD...FQSGL.APLRSPQSEEDTQQIEN....E..CLGMAVMAISHDAMGSQM..PTREL.TRIF...K.........Y.KNYIPLSFRQDIAQRNIFTRMRIANVFKAFLE.EFN..D..RTIQNSSVSKHYLKVKYISTLENL....................................................
A0A091CUK2_FUKDA/179-309             .............TPLLDASSLEYLFAQ.GQHD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMVKKV..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
H9H626_MONDO/79-209                  .............TPLLDAHSLEYLFAQ.GQYD...LVKCL.APVRDPKTDQEVHEIEN....E..CLGMAVLAISHYAMMKSI..QLPDL.PKDV...S.........Y.KRYIPETLNRTIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVTPHDLKVKYLSTLETL....................................................
F1LR79_RAT/126-245                   .............SAILDVHVLEHLFAQ.HRSD...LVSGR.LPVGLSLKDQG------....E..FLSLAVLDLAQMARKQAQ..RPGEL.LKSV...S.........Y.KACLPPSLRDLIQGQSFVTRRRIRRTVVQALR.RVV..-..----ACQADRYALMAKYILDLERL....................................................
A0A094L2N6_9AVES/67-186              .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
G3W042_SARHA/139-269                 ............c-ALLDKASFEYLYEQ.GKFE...FVNDV.ASLSDLHSDAEVQHFKN....E..SLGMAVLHLSHLALQRGV..PLEEV.VRKT...S.........F.KDCIPCSFSRQIQQNNSLTKFRLRNVFQKFMR.RFH..L..QTVGPGRFSEQDIMFKYLATLEQL....................................................
A0A2I4BES6_9TELE/137-256             ............n-PVLDYNVIDYLFSQ.MRSD...FVASQ.AGIAPPLSAQE------....E..CLGLAVLDLWRMAKERHQ..SVREL.CKTV...S.........Y.KSCLPKSHRLDIQKRNRLDRFRIRKSLKRFMK.KLG..-..----NCSVDVCSLKLKYLIEL---agi.................................................
K7GME4_PIG/147-277                   .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A2K5NHQ0_CERAT/153-283             .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A2I3RSB7_PANTR/141-266             ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRHGI..PLQEV.AKKT...S.........F.KDCIPRSFRRHIRQHSALTRLRLRNVFRRFLR.DFQ..-..----PGRLSQQMVMVKYLATLERL....................................................
T0M5G5_CAMFR/142-267                 ............i-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFQN....E..SLGMAFLHLCHLALRDGV..PLEKV.AKKI...S.........F.KDCIPCSFRRQIQQHNVLTRLRLRSIFRRFLR.AFQ..-..----PGCLSQQVVMVKYLATLEQL....................................................
H0YE41_HUMAN/1-45                    ............x---------------.----...-----.-----------------....-..------------------..-----.----...-.........-.-----------IRQHSALTRLRLRNVFRRFLR.DFQ..-..----PGRLSQQMVMVKYLATLERL....................................................
A0A1U7RXD8_ALLSI/147-277             .............SPILDGHSLEYLFAQ.GQHD...LVKGL.APVRDPKNDQEIHEIEN....E..CLGMAVLAISHFAINKNT..KLPDL.PKDI...S.........Y.KRYIPETLNKSIRQRNILTRIRINNVFKEFLK.EFN..N..KTICDSSVSPHDLKVKYLSTMETL....................................................
A0A0F8AEQ5_LARCR/116-246             .............SPLLEITALEYLFSQ.AKYE...FVNEV.VQMEDVQSEEELSRFKN....E..SLGMAVLHLSHQAMQTGS..TLQDV.AKKV...S.........F.LRCIPRSFAKHISKDNFLTKIRIRRVFSDFVQ.TFQ..Q..HTVDKGRLGTHEIMYKYISTLEHL....................................................
B4NE99_DROWI/160-279                 ...........rf---IDQQSFNYLYYQ.MRHD...MVHE-.-QISEIRYPDH----KN....K..VLGLAVIDMR-IDLESQP..SAAEA.IQ-R...A.........Y.KTYLPHSLWN---NHGLFTRPHIHNVFQELIA.---..-..------------------------ssldfadfkfhyissicslaptymmeqyr.......................
TYK2_MOUSE/144-269                   ............v-QLLDSASFEYLFEQ.GKHE...FMNDV.VSLRDLSSEEEIHHFKN....E..SLGMAFLHLCHLALSRGV..PLEEM.AREI...S.........F.KNCIPHSFRQHIRQHNVLTRLRLHRVFRRFLR.AFR..-..----PGHLSQQVVMVKYLATLERL....................................................
K7G2T9_PELSI/140-259                 .............SPVFDDLVMSYLFAQ.WRED...FVHGW.IKIPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAV.YNSV...S.........Y.KNFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKASARNLKLKYLINLESL....................................................
F7GT47_MACMU/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPECIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
G1MVV3_MELGA/102-232                 .............TAVLDRASFQYLFEQ.GKFD...FINDA.ASLTDFQSEQEVQRFKN....E..SLGMAVLHLCHIALRGGR..CLEEV.ARKY...S.........F.KACIPRSFRLQIQQSSAVTRLRMKNVFRKFVR.RFQ..R..HTVGAGTLTEEDVMFKYLATLELL....................................................
I3K428_ORENI/138-257                 .............SPVLNYSVIDYLFAQ.LRND...FIESK.AGVAPPLSLQE------....E..CLGLAVLDLWRMAKERNQ..SVREL.CKTV...S.........Y.KSCLPKSHRHDIQKRNRLDRYRIRNTLKRFLK.KLG..-..----NCSVDECSLKLKYLIEL---agi.................................................
F7DRD4_MACMU/141-266                 ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PLEEV.AKKT...S.........F.KDCIPLSFRRQIRQHSALTRLRLRNVFRRFLQ.DFQ..-..----PDRLSQQMVMVKYLATLERL....................................................
H2SBF2_TAKRU/157-276                 .............TPVMDDSVMAYLFLQ.WRSD...FLNGR.VNVPGSHEAQE------....E..CLGMAVLDMMRLAKETNQ..SPVSI.CSST...S.........Y.KTFLPRGMQDRIQEYNMLTRKRIRYRFCKFIQ.HFS..-..----ECKATVANLKLKYLMSLEML....................................................
F6TJR2_ORNAN/67-186                  ............a-PLLDDYIMSYLFAQ.WRDD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAI.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
F7DKS0_XENTR/134-264                 .............TPLLDASSLDYLFAQ.GQYE...LVKCL.APVREPKNDQEVHEIEN....E..CLGMAVLAISHYAIKRNI..QLPDL.PKDI...S.........Y.KKYIPETLNRTIKQRNFLTRMRINNVFKNFLK.EFN..N..KTICDSSVSPHDLKVKYLSTMETL....................................................
S7MJU2_MYOBR/70-189                  ............a-PLLDDFVMSYLFAQ.WRHD...FLHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLDV.YSSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
G3IEQ4_CRIGR/132-251                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAV.YNSV...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
G3QWD9_GORGO/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
I3K427_ORENI/131-250                 .............SPVLNYSVIDYLFAQ.LRND...FIESK.AGVAPPLSLQE------....E..CLGLAVLDLWRMAKERNQ..SVREL.CKTV...S.........Y.KSCLPKSHRHDIQKRNRLDRYRIRNTLKRFLK.KLG..-..----NCSVDECSLKLKYLIEL---agi.................................................
H3C837_TETNG/27-146                  .............SPVFDDCVMSYLFSQ.WRND...FVNGF.VKIPSSHEIQE------....E..CLGMAVLDMTRTAKERQL..SPLDI.YHTM...S.........Y.KSFLPKEIRAQIQDCNFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISMESL....................................................
H2N755_PONAB/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A1U7T2Q1_TARSY/132-187             ...........pv---------------.----...-----.-----------------....-..------------------..-----.----...-.........-.-ACLPPGLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLIAKYIMDLERL....................................................
A0A2I0MC95_COLLI/147-277             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAINKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
A0A1A6GPP0_NEOLE/78-208              .............TPLLDASSLEYLFAQ.GQYD...LIKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
Q9TTJ0_PIG/142-261                   ............a-PLLDDFVMSYLFAQ.WRHD...FLYGW.VKIPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLDI.YSSV...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
JAK3_MOUSE/126-245                   .............SAILDLHVLEHLFAQ.HRSD...LVSGR.LPVGLSMKEQG------....E..FLSLAVLDLAQMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDVIQGQNFVTRRRIRRTVVLALR.RVV..-..----ACQADRYALMAKYILDLERL....................................................
F7BLR3_HORSE/1-86                    .............---------------.----...-----.-----------------....-..---MAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSMHDLKVKYLATLETL....................................................
E9PPF2_HUMAN/141-266                 ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSTEEEIHHFKN....E..SLGMAFLHLCHLALRHGI..PLEEV.AKKT...S.........F.KDCIPRSFRRHIRQHSALTRLRLRNVFRRFLR.DFQ..-..----PGRLSQQMVMVKYLATLERL....................................................
A0A0R4J0R7_MOUSE/126-245             .............SAILDLHVLEHLFAQ.HRSD...LVSGR.LPVGLSMKEQG------....E..FLSLAVLDLAQMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDVIQGQNFVTRRRIRRTVVLALR.RVV..-..----ACQADRYALMAKYILDLERL....................................................
A0A287A997_PIG/141-266               ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFQN....E..SLGMAFLHLCQLALRHGV..PLEKV.AKKI...S.........F.KDCIPRSFRRQIRQHNALTRLRLRSIFRKFLR.AFQ..-..----PGCLSQQVVMVKYLATLERL....................................................
F1Q6A2_DANRE/119-238                 .............SPVLDDYVMSYLFAQ.WRSD...FVNGW.VKLSGSHENQE------....E..CLGMAVLDMMRTAKEKDC..SPLDI.YNDI...S.........Y.KSFLPKDMRERIQDYHFVTRKRIRYRFRKVVQ.QLS..-..----QCRATARDLKLKYLISLESL....................................................
A0A091SDR0_NESNO/146-276             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.PKDM...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVTSRDLKVKYLSTMETL....................................................
A0A1U8C602_MESAU/146-271             ............v-QLLDSASFEYLFEQ.GKHE...FMNDV.VSLRDLSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PLEEM.AREI...S.........F.KKCIPRSFRQHISQHNALTRLRLRRVFRRFLR.AFQ..-..----PDHLSQQVVMVKYLATLERL....................................................
S7NZR3_MYOBR/155-280                 ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PLEKV.AKKT...S.........F.KDCIPRSFRQQIQQYNAFTRLRLRIIFRKFLH.AFQ..-..----PDSLSQHIVMVKYLATLERL....................................................
G3PZA6_GASAC/146-265                 .............SPVMDDCIMAYQFLQ.SRSD...FLNGR.VDIPVSHEAQE------....E..CLGMAVLDMMRLAKENAQ..SPLDI.YNST...S.........Y.KSFLPRCMQSRIQEYNILTRKRIRYRFRKFIQ.QFG..-..----ECKATVCNLKLKYLMSLEML....................................................
A0A1V4J8Q4_PATFA/135-254             .............SPVLDDIVMSYLFAQ.WRDD...FLDGW.VQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A226NGA7_CALSU/163-293             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
A0A0A0MTV7_PAPAN/141-266             ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRRGV..PLEEV.AKKT...S.........F.KDCIPLSFRRQIRQHSALTRLRLRNVFRRFLQ.DFQ..-..----PDRLSQQMVMVKYLATLERL....................................................
M3YWH9_MUSPF/126-245                 .............SAVLDLPVLEHLFAQ.HRND...LVSGR.LSVGLSLKEQG------....E..CLSLAVLDLARMAREQVQ..QPEEM.LKTV...S.........Y.KVCLPPDLRDLIQGLSFVTRKRIRRTVRRALR.RVT..-..----ACQADRHSLMAKYIMDLERL....................................................
W5Q3B2_SHEEP/142-267                 ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLCELSSEEEIHHFQN....E..SLGMALLHLCHLALRSGV..PLEKV.AKKT...S.........F.KDCIPRSFRRQIRQHNVLTRVRQRSIFRKFLQ.AFQ..-..----PGCLSQQVIMVKYLATLERL....................................................
A0A093J647_EURHL/147-277             .............TPILDASSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
G1RCI3_NOMLE/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPTCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLEAL....................................................
H0ZIA6_TAEGU/134-264                 .............TPILDSDSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHDAIKKNM..KLPEL.PKDI...S.........Y.KHYIPETLNRTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICNNSVSPRDLKVKYLSTMEIL....................................................
A0A0D9R4G8_CHLSB/141-266             ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRRGV..PLEEV.AKKT...S.........F.KDCIPLSFRRQIRQHSALTRLRLWNVFRRFLQ.DFQ..-..----PDRLSQQMVMVKYLATLERL....................................................
M3ZLD9_XIPMA/144-263                 .............SPVLDDYVMTYLFSQ.WRND...FVNGV.VMISDSHESQE------....E..CLGMAVLDMTRTAKERQM..SPLDI.YHNT...S.........Y.KSFLPKDMRNQIQDCSFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISIESL....................................................
A0A218UJX7_9PASE/146-276             .............TPILDSDSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHDAIKKNM..KLPEL.PKDI...S.........Y.KHYIPETLNRTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICNNSVSPRDLKVKYLSTMEIL....................................................
G3PKI3_GASAC/141-260                 .............SPVLDDFVMSYLFSQ.WRND...FINGR.VKVPNSHETQE------....E..CLGMAVLDMTRTAKERQM..SPLDI.YHTT...S.........Y.KSFLPKDMSAQIKDCNFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISMESL....................................................
H2TE40_TAKRU/107-237                 ...........ls--LFDVRSLDYLFSQ.AKYE...FVNKI.VHMEDMKTEEEISSFKN....E..SLGMAVLHMSHQALQTGS..TLQEV.AKKH...S.........Y.LDCIPKCFAKHISKDNFLTKIRIRRVFADFVQ.TFQ..E..HTVENGRLDTQKIMYKYISTLERL....................................................
A0A091USR2_NIPNI/147-277             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDEEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
F7CMB7_XENTR/142-272                 ............g-AILDLASFEYLFEQ.GKFD...FVNDV.VSLKDFSMEQDIHRFKN....E..SLGMAVLHLSHIAIKKKV..SLEEV.AKQI...S.........F.KECIPKSFCRQIQQNNYLTKFRMKNVFKKFVR.RFH..L..HTVSPGKLNEEDIMYKYLSTLENL....................................................
F6W791_CALJA/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A2K5L5K0_CERAT/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A1V4KY01_PATFA/170-300             ............g-ALLDKSSFEYLFEQ.GKYD...FINDV.APLRDAQGEQELQRFKN....E..CLGMAVLHLSHVALTRGL..SLEDV.ARKY...S.........F.KNCIPRSFRRQLQQNSYLTRFRLKSVFRRFVR.RFQ..R..HTVGAGRLTAQDVMYKYLATLEQL....................................................
A0A087VNE1_BALRE/95-225              ............g-ALLDKSSFEYLFEQ.GKFE...FINDV.ASLKDLQTEQEIQRFKN....E..SLGMAVLHLSHIAIKKGI..SLEEV.ARKY...S.........F.KDCIPRSFYRQIQQNNYLTKFRMKNVFKKFVQ.RFQ..R..HTVSTGKLTVQDIMYKYLATLEHL....................................................
G3U018_LOXAF/151-281                 ............l-PLLKAESPEVVFVQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
G7NW22_MACFA/135-265                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
G3RIC1_GORGO/126-245                 .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
A0A091W7X1_NIPNI/108-227             .............SPVLDYPVIDYLFAQ.SRSD...FIGGR.VAVALSLPTQE------....E..CLSLAVLDMLRIAKEKRQ..SPDEV.FSHV...S.........Y.KSCIPEPLRCQIQQHSFLTRKRIRRRFSKSLR.KIG..-..----GCQTDGCYLKLKYLLDLERL....................................................
A0A1U7RLB6_ALLSI/140-259             .............SPVLDDLVMSYLFAQ.WRDD...FVDGW.IKMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHFLTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
F7D542_ORNAN/174-247                 ...........eg--LLDQASFEYLFEQ.GKFD...FVNDV.VSLWEQPSEAEVCRFKN....E..SLGMAVLHLAHLALRQGV..PIWDV.AKTT...R.........F.L-------------------------------.---..-..------------------------rg..................................................
A0A2I4CIS9_9TELE/131-261             .............SPLLDITSLEYLFAQ.AKYE...FVNEV.AQMEDIESEEELSRFKN....E..SLGMAVLHLSHLAIQKNS..TLQEV.AKKH...S.........F.LECIPVSFAQHISRDNFLTKIRIRRVFSDFVR.TFQ..Q..HTVDIGHLGAQEIMYKYISTLEHL....................................................
G1SQL4_RABIT/147-277                 .............TPLLDANSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMRKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A1L8GLW3_XENLA/133-263             .............TPLLDASSLDYLFAQ.GQYE...LVKCL.APVREPKNDQEVHEIEN....E..CLGMAVLAISHYAMKRNI..QLPDL.PRDI...S.........Y.KKYIPETLNRTIKQRNFLTRMRINNVFKNFLK.EFN..N..KTLCDSSVSPHDLKVKYLSTMETL....................................................
A0A1S3FJH6_DIPOR/147-277             .............TPLLDASSLEYLFAQ.GQYD...LIKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMIKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
JAK2_PONAB/142-261                   ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
H2LQD3_ORYLA/133-254                 .............SPVLDYNVIDYLFAQ.VKYK...VIYLI.DPVCQE-------KIIV....R..CLTFSLVTSSKLQKLNNQ..IVDII.SNQIlffS.........Y.KSCLPKSHRHDIQKRNRLDRYRIRNTLKRFLK.KLG..-..----NCSVDECSLKIKYLMEL---agi.................................................
A0A087XVK1_POEFO/145-275             .............TPLLDVGSLEYLYFQ.CQHD...FQTGK.APLRAAQSEAEQHEIEN....E..CLGMAVLAITHYAKDIGI..PFSAA.SREM...S.........Y.KRFIPESLNSIIKQRNILTRIRISNVFKKFLA.EFN..T..QTVGESNITCYDLKIKYLATMEGL....................................................
S9YWR6_CAMFR/143-262                 ............c-AILDLPVLEHLFAQ.HRND...LVSGC.LPVGLSLKEQG------....E..CLSLAVLDLARMALEQAQ..RPEEL.LKTI...S.........Y.KVCLPPGLRDLIQGLSFVTRKRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
L5LTA8_MYODS/142-267                 ............v-QLLDAASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PLEKV.AKKT...S.........F.KDCIPRSFRQQIRQYNAFTRLRLRIIFRKFLH.AFQ..-..----PDSLSQQVIMVKYLATLERL....................................................
A0A1U7SPN9_TARSY/141-260             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRARIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0JM01_XENTR/140-259                 .............SPVLDDVVMAYLFAQ.WRDD...FVNGR.ITVPITHEAQE------....E..CLGMAVLDMMRMASEKGQ..SPLAV.YNSV...S.........Y.KKFLPKCIRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARDLKLKYLINLETL....................................................
U3KDU1_FICAL/146-276                 .............TPILDANSLEYIFAQ.GQYD...LVKGL.APVREPRSEQEGHEIEN....E..CLGMAVLAISHDAIKKNV..KLPEL.PKDI...S.........Y.KHYIPESLNRTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICNNSVSPRDLKVKYLSTMEIL....................................................
B4JJT9_DROGR/131-253                 ...........sa---IDAQCQNYLYHQ.MRYD...MLHEQ.INEIRYPEH------KD....K..VMGLAVMDMIIDKDEKQL..QAEAI.EK--...A.........Y.KSYLPHTLWR---AHRIFVRPKIRRSFRQMSRdQFN..C..DTLKWH------------------yvhqichlaptylteqfkatv...............................
F8W4H3_DANRE/134-264                 .............SHLLELSALEYLFAQ.AKYD...FVNDL.VPLNAVSGEEEIGRYQN....E..CLGMAVLHLSYTALQTGS..SLQDV.AKQT...S.........F.LRCIPLSFSRHIAKQNILTRFRIRRVFAHFVN.TFQ..Q..HTVGVGKLGSQEVMYKYLSTLERL....................................................
F6TV83_CIOIN/137-264                 ............k-PVMSDQVIEYLFYQ.CRDD...FLNS-.----SEKDTAEMSDPLG....A..SLGVAVLDMLRLAREMDC..DLSCI.KSQV...S.........F.KKLLPRACRANLSKMNFCNRYRVERRFMYYLR.HFS..PvcRTWLASQCSPAYFYSKYIRNLEL-i...................................................
W5MIP2_LEPOC/145-273                 .............TPLLDAASLEYLFAQ.GQYD...FLKGL.APVRSPQNENETHDIEN....E..CLGMAVLAITHHTMRK--..SMAGS.AGET...S.........Y.KKYIPETLNKAIKQRNFLTRIRINNVFKSFLN.EFN..N..KTVTDSNVTMHDLKVKYLSTLETL....................................................
G3P1H3_GASAC/131-250                 .............SPVFDCSVIDYLFSQ.LRSD...FIACE.AGVCPPLSAQE------....E..CLGLAVLDLWRMAKERHQ..SVKEL.CMTV...S.........Y.KSCLPMSHREDIQRRNRLDRYRIRNTLKRFLK.KLG..-..----SCSIDECSLKLKYLIEL---agi.................................................
W5KTH7_ASTMX/145-279                 .............TPLLDAASLDYLFAQ.GQYSeyrLQSLS.APAISVHSHNE--SIPNpfafT..SLSAITIHACSINLLLTG..SPSG-.SVTC...S.........Y.KRFIPESLNRTIKQRNFLTRLRISNVFKNFLN.EFN..S..KTIKDSNISLYDLKVKYLSTLETL....................................................
M3ZDE9_XIPMA/132-259                 .............SPLLDITSLEYLFAQ.AKHE...FVNN-.--VEEPKSDVENNRFKN....E..SLGMAVLHLSHLAMQKGL..NLQEV.AGKI...G.........F.QNCIPRTFAENISRDNFLTKIRIRRVFTEFVQ.TFQ..Q..HTVDKGQLGAHEIMYKYISTLENL....................................................
A0A1S3KQI9_SALSA/175-294             .............SPVLDDTVMSYLFAQ.WRSD...FVDGW.VSIPVNHEAQE------....E..CLGMAVLDMMRMAKESSQ..APVDI.FNDT...S.........Y.KSFLPKDIRARIQEYHFVTRKRIRHRFKKFIQ.QFC..-..----QCNATARDLKLKYLANLEML....................................................
A0A1V4KXU7_PATFA/170-300             ............g-ALLDKSSFEYLFEQ.GKYD...FINDV.APLRDAQGEQELQRFKN....E..CLGMAVLHLSHVALTRGL..SLEDV.ARKY...S.........F.KNCIPRSFRRQLQQNSYLTRFRLKSVFRRFVR.RFQ..R..HTVGAGRLTAQDVMYKYLATLEQL....................................................
G3RK14_GORGO/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
F7DHF9_CALJA/142-261                 ............a-PLLDDCVMSYLFSQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A1V4JXL8_PATFA/147-277             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAINKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
A0A218VAM0_9PASE/140-259             .............SPVLDDLVMSYLFAQ.WRAD...FLDGW.VQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPMAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A151ML06_ALLMI/162-225             .............SAVLDQPVIDYLFAQ.SRSD...FLRGL.VAGVLSWQTLE------....A..CLCLAVLDMLRIAKERRQ..SLDHV.FS--...-.........-.--------------------------------.---..-..------------------------cvr.................................................
A0A2D0SYU4_ICTPU/126-245             ............a-PVFDDVTTAYLFAQ.WRSD...FVDGS.VSIPVTHDAQE------....E..CLGLAVLDMMRIAKEKGC..SPIKI.YHDY...S.........Y.KSFLPKAIRAHIQRYHIVTRKRIRYRFRRFVE.RLR..-..----LCRAPVTELMLKYVASLEVL....................................................
M3ZJ44_XIPMA/145-275                 .............TPLLDVGSLEYLYFQ.CQHD...FQTGK.APLRAAQSEAEQHEIEN....E..CLGMAVLAITHYAKNFDI..PFSAA.SREM...S.........Y.KRFIPESLNSNIKQRNILTRIRISNVFKKFLA.EFN..T..QTVGESNITCYDLKIKYLATMEGL....................................................
F7F934_MONDO/126-244                 ............n-AILDFPVLEYLFAQ.SRND...FISGR.MNLTLNLKEQG------....E..CLSLAVLDLTRMDKEQGL..TLRA-.FSSL...S.........Y.KACIPASFRRLIQSLSFMTRKRYRQMVRRALQ.RVA..-..----SCQADVHFIMLKYLMDLERL....................................................
A0A2K5IGU5_COLAP/153-283             .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
B1ASP2_MOUSE/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LIKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A091UD74_PHORB/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A0N8K0F6_9TELE/144-263             .............TPVLDDSVMAYLFAQ.WRSD...FVSGS.IDVAVNHEAQE------....E..CLGMAVLDMMRIAKEKDL..SPLDI.YNDM...S.........Y.KSFLPKDMRARIQDYHIVTRKRIRYRFKKFIQ.QFS..-..----QCKATARDLKLKYLMNLEAL....................................................
A0A093CGK4_TAUER/41-171              .............TPILDASSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKDM..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
H2L7P7_ORYLA/141-260                 .............SPVLDDSVMSYLFYQ.WRND...FVNGL.VKISNSHEMQE------....E..CLGMAVLDMTRTAKEKQT..SPLEI.YDTM...S.........Y.KSFLPKDIRAQIQDCSFLTRKRIRFRFKRFIQ.QFS..-..----HCRTTVWDLKLKYLISIESL....................................................
H2M2B1_ORYLA/155-274                 .............SPVMDDCVMAYLFSQ.WRND...FLNGW.VHIPVSHEAQE------....E..CLGMAVLDMMRLAKENGQ..SPVDI.YNDT...S.........Y.KSFLPRSMRGRIQEYNLLTRKRIRFRFRRFIQ.QFG..-..----ECKATICNLKLKYLMNLEML....................................................
G3QT84_GORGO/141-266                 ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRHGI..PLEEV.AKKT...S.........F.KDCIPRSFRRHIRQHSALTRLRLRNVFRRFLR.DFQ..-..----PGRLSQQMVMVKYLATLERL....................................................
H2PS83_PONAB/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
G1KHZ7_ANOCA/140-270                 .............SAILDKSSFEYLFEQ.GKYD...FINDV.ASLKDLRTEQEIHQFKN....E..SLGMAVLHLCHIALKSGL..SLEEV.AQRT...S.........F.KECIPRSFCRQIQQNNYLTKFRIRNVFRRFLQ.RFQ..R..HTMSTGKLTEQDIMHKYLATLENL....................................................
A0A1S3LTD3_SALSA/140-259             .............SPVFDDTVMSYLFAQ.WRSD...FVHSW.VIIPVNHEAQE------....E..CLGMAVLDMMRMAKESSQ..SPVDI.YNDT...S.........Y.KSFLPKNMRAHIQEYHFVTRKRIRHRFRKFIQ.QFS..-..----QCKATARDLKLKYLVNLETL....................................................
A0A1D2NKP5_ORCCI/91-202              ............q----DPNAFDYTFHQ.IRHD...VLHGD.IP--EILLEQR----KS....E..ALGLCVTDMLRTILEDGV..AQSF-.-VEN...N.........Y.RQYIPKFIYK---YPPFFLKKRIHENLTRLVS.QAQ..-..----GYHTNTKFIKEQYISHLEE-i...................................................
A0A096N179_PAPAN/146-276             .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A1S3FBE8_DIPOR/143-206             ......vrdyfip---------------.----...-----.-----------------....-..------------------..-----.----...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYVINLETL....................................................
A0A0P7WH47_9TELE/160-258             .............SPVLDDCVMEYLFAQ.V---...-----.---AISHETLE------....E..CLGMAVLDIMRVAKENE-..-----.----...N.........Y.KSFLPQNVRACIQDYHFVTRKRIRYRFRKFVE.QLN..-..----LCKVTARDLKLKYLINLESL....................................................
A0A2I0LJ08_COLLI/171-301             ............g-AVLDKSSFEYLFEQ.GKYD...FINDV.APLRDAQGEQELQRFKN....E..CLGMAVLHLSHVALTRGL..SLEDV.ARSY...S.........F.KNCIPRSFRRQIQQNNYLTRFRLKNVFRRFVQ.HFQ..R..HTVGAGRLTAQDVMYKYLATLEQL....................................................
A0A091KK52_9GRUI/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLNGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A1S3LTH7_SALSA/140-259             .............SPVFDDTVMSYLFAQ.WRSD...FVHSW.VIIPVNHEAQE------....E..CLGMAVLDMMRMAKESSQ..SPVDI.YNDT...S.........Y.KSFLPKNMRAHIQEYHFVTRKRIRHRFRKFIQ.QFS..-..----QCKATARDLKLKYLVNLETL....................................................
K7FRH1_PELSI/148-278                 .............TPILDANSLEYLFAQ.GQYD...LVKCL.APVRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNM..KLPEL.PKDI...S.........Y.KRYIPETLNKTIRQRNILTRIRINNVFKDFLK.EFN..N..KTICDSSVSPHDLKVKYLSTMETL....................................................
H2SBF3_TAKRU/89-204                  .............TPVMDDSVMAYLFLQ.WRSD...FLNGR.VNVPGSHEAQE------....E..CLGMAVLDICSSTS---L..SLPP-.NDTS...S.........Y.KTFLPRGMQDRIQEYNMLTRKRIRYRFCKFIQ.HFS..-..----ECKATVANLKLKYLMSLEML....................................................
E9PM19_HUMAN/1-81                    .............---------------.----...-----.-----------------....-..---MAFLHLCHLALRHGI..PLEEV.AKKT...S.........F.KDCIPRSFRRHIRQHSALTRLRLRNVFRRFLR.DFQ..-..----PGRLSQQMVMVKYLATLERL....................................................
A0A1U8DDU7_ALLSI/159-276             .............SALLDRASFEYLFEQ.----...-----.----DLATEQDLHRFKN....E..SLGMAVLHLSHLALRRGL..SLEEA.AKKC...S.........F.KDCIPWSFRRQIQQSSSLTRLRLRSVFRRFVQ.HFQ..R..HTVGAGRLTEQGVMYKYLATLESL....................................................
F6X395_ORNAN/38-168                  .............TPLLDANSLEYLFAQ.PLQG...ERRPH.PPARSPGWIQEVHEIEN....E..CLGMAVLAISHYAKKKNV..QLPEL.SKDI...S.........Y.KRYIPETLNRTIRQRNMLTRMRINNVFKDFLK.EFN..N..KTICDSSVSAHDLKVKYLSTLETL....................................................
I3JQC0_ORENI/145-275                 .............TPLLDADSLTYLFTQ.SQND...FQTGV.VPLRSPQSEAEQHEIEN....E..CLGMAVLAITHYAMNEKM..PLSTA.SHEI...S.........Y.KRFIPDSLNRNIKQRNILTRIRINNVFKKFLT.EFN..S..RTVKDSNITTYDLKIKYLATLEGL....................................................
H3CH80_TETNG/157-276                 .............SPVMDDDVMAYLFSQ.WRSD...FLSGR.VPVPGSHEAQE------....E..CLGMAVLDMMRLAREQGQ..SPGSI.CSST...S.........Y.KAFLPRCMRERIREYNFVTRKRIRYRFHRFIQ.QFG..-..----ECKVAVGNLKLKYLMSLEML....................................................
A0A1S3LUJ9_SALSA/140-259             .............SPVFDDTVMSYLFAQ.WRSD...FVHSW.VIIPVNHEAQE------....E..CLGMAVLDMMRMAKESSQ..SPVDI.YNDT...S.........Y.KSFLPKNMRAHIQEYHFVTRKRIRHRFRKFIQ.QFS..-..----QCKATARDLKLKYLVNLETL....................................................
A0A1A6HMC7_NEOLE/146-271             ............v-QLLDSASFEYLFEQ.GKHE...FMNDV.VSLRDLSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PLEEM.AREI...S.........F.KNCIPRSFRQHIRQHNALTRLRLRRVFRRFLR.AFQ..-..----PGHLSQQVVMVKYLATLERL....................................................
H2TE41_TAKRU/117-251                 vllhtnsislfys---------HYLTAF.AKYE...FVNKI.VHMEDMKTEEEISSFKN....E..SLGMAVLHMSHQALQTGS..TLQEV.AKKH...S.........Y.LDCIPKCFAKHISKDNFLTKIRIRRVFADFVQ.TFQ..E..HTVENGRLDTQKIMYKYISTLERL....................................................
A0A2I4CI67_9TELE/144-263             .............SPILDDYVMSYLFSQ.WRND...FVNGF.VKISDSHETQE------....E..CLGLAVLDMTRTAKEKQL..PPLDI.YHSI...S.........Y.KSFLPKDMRAQIQDCSFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISIESL....................................................
A0A096LWM8_POEFO/133-252             ............s-LVLDYNVIDYLFAQ.LRSD...FIASE.AGIVPPLSAQE------....E..CLGLAVLDLWRMAKERRQ..TIREL.CKTV...S.........Y.KSCLPKSHRHEIQKRNRLDRFRIRNTLKRFLK.KLG..-..----KCSVDEYSLKLKYLIEL---agi.................................................
A0A1U7R3C7_MESAU/146-271             ............v-QLLDSASFEYLFEQ.GKHE...FMNDV.VSLRDLSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PLEEM.AREI...S.........F.KKCIPRSFRQHISQHNALTRLRLRRVFRRFLR.AFQ..-..----PDHLSQQVVMVKYLATLERL....................................................
A0A091EVH4_CORBR/145-275             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNEQEVHEIEN....E..CLGMAVLAISHDAIKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICNNSVSPRDLKVKYLSTMEIL....................................................
JAK2_HUMAN/142-261                   ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
#=GR JAK2_HUMAN/142-261        SS    ............B--SS-HHHHHHHHHH.HHHH...HHTTS.S----SHHHHH------....H..HHHHHHHHHHHHHHHTT-..-HHHH.HTTS...-.........G.GGGS-HHHHHHHHTS-HHHHHHHHHHHHHHHH.HTT..-..----T----HHHHHHHHHHHHHHH....................................................
I3M210_ICTTR/155-280                 ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.VSLWELSSEEEIHHFKN....E..SLGMAFLHLSHLALQRGV..PLEEV.AKEI...S.........F.KDCIPLSFRQQIRQHNALTRLRLRNVFRKFLH.AFQ..-..----PGHLSQQMVMVKYIATLEHL....................................................
W5PK80_SHEEP/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKV..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A2K5IU17_COLAP/141-266             ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRRGV..PLEEV.AKKT...S.........F.KDCIPLSFRRQIRQHSALTRLRLRNVFRRFLQ.DFQ..-..----PDRLSQQMVMVKYLATLERL....................................................
A0A093QTD9_PYGAD/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A151M8K3_ALLMI/135-254             .............SPVLDDLVMSYLFAQ.WRDD...FVDGW.IKMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHFLTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A226MBR6_CALSU/292-422             .............TAVLDRASFEYLFEQ.GKFD...FINDV.ASLTDFRTEAEVQRFKN....E..SLGMAVLHLAHIALRSGR..CLQDV.ARKY...S.........F.QECIPRSFRHQIQRNSAVTRFRMRNVFRRFVR.RFQ..Q..HTVGAGKLAEQDVMFKYVATLEQL....................................................
H3CXH8_TETNG/121-240                 .............SPVLDHSGIAYLFAQ.LRTD...FTSSE.AGLSPPLTTQD------....E..CLGLAVLDLWRLAKEQQS..SVKDL.CKSV...S.........Y.KSCLPKSHRVDIEKRNWVERFRIRNTLKHFLK.KFG..-..----SCAVDDCNLKLMYLTAL---agi.................................................
G3TF05_LOXAF/86-207                  .............SAILDLPVLEHLFAQ.HRSD...LVSGH.LPVGLSLKEQG------....E..CLSLAVLDLTRMAKEQAH..RPEKL.LKKVr.rS.........Y.KTCLPPGLRDLIQGLSFVTRKRIRRTVLLALR.RVA..-..----ACQADRQSLMAKYIMDLQRL....................................................
A0A2D0R0L4_ICTPU/129-248             ............c-AVLDYSVIDYLFAQ.SRSD...FVSGC.GGVRPPVSAIQ------....E..CLDLAVLDLWSQAKEKNH..SVKEV.CKTI...S.........Y.KSCLPETHREEIQRMTRLARYQIRKNLKHFLK.KLG..-..----RCSAGERSLKLKYLMELS--sv..................................................
A0A0N8JZU0_9TELE/110-241             .............TPLLEQPCLEYLFAQ.AKFD...FVNDV.ASLDEVQEEQELSRFKS....E..CLGMAVLHLCQQALQSGC..TLQDM.AKKT...R.........QdDSCIPRSFAMQIQRDNFLTKVRIRRVFSQFVR.SFQ..L..HTVGTGRLTQQDIMYKYVATLEHL....................................................
JAK3_HUMAN/126-245                   .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
G1T864_RABIT/139-264                 ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEETHHFKN....E..SLGMAFLHLCHLALCRGV..PLEEV.ARKT...S.........F.KDCIPRSFRQQIHQHNALTRLRLRNVFRRFLR.AFQ..-..----PGRLSQQAVMVKYLATLERL....................................................
W5MIN0_LEPOC/145-277                 .............TPLLDAASLEYLFAQ.GQYD...FLKGL.APVRSPQNENETHDIEN....E..CLGMAVLAITHHTMRKSMagSAGET.RKQI...N.........Y.KKYIPETLNKAIKQRNFLTRIRINNVFKSFLN.EFN..N..KTVTDSNVTMHDLKVKYLSTLETL....................................................
A0A2I3LGP0_PAPAN/147-277             .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
G1PL96_MYOLU/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FLHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLDV.YSSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
A0A091T8G5_PHALP/95-225              ............g-ALLDKSSFEYLFEQ.GKFE...FINDV.ASLKDLQTEQEIQRFKN....E..SLGMAVLHLSHIAIKKGI..SLEEV.ARKY...S.........F.KDCIPRSFYRQIQQNNYLTKFRMKNIFKKFVQ.HFQ..R..HTVSTGKLTVQDIMYKYLATLEHL....................................................
G5E852_MOUSE/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAV.YNSV...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
JAK1_HUMAN/147-277                   .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
#=GR JAK1_HUMAN/147-277        SS    .............B-SEEHHHHHHHHHH.HHHH...HHTTS.S-B---SSHHHHHHHHH....H..HHHHHHHHHHHHHHHTT-..STTT-.----...-.........G.GGGS-HHHHHHHHTS-HHHHHHHHHHHHHHHH.HHH..H..THHHHTT--HHHHHHHHHHHHHHH....................................................
H2P0I2_PONAB/1-111                   ............g---------------.-KHE...FVNDV.ASLWDLSSEEEIHHFKN....E..SLGMAFLHLCHLALRHGI..SLEEV.AKKT...S.........F.KDCIPRSFRRHIQQHSALTRLRLRNVFRRFLR.DFQ..-..----PGRLSQQMVMVKYLATLERL....................................................
A0A1S3WF45_ERIEU/142-267             ...........lq--LLDPASFEYLFEQ.GKHE...FVNDV.VSLDELSSEEELHHFKN....E..SLGMAFLHLCHLALRRGI..PLQEV.ARKT...S.........F.LDCIPRSFRRQIRQHNPLVRLRLRTIFLRFIC.TFP..-..----RERLALPVVQAKYLATLERL....................................................
W5ML83_LEPOC/152-282                 .............SPLLDQPSLEYLFAQ.GKHD...FVNDA.VSLQDIRTEAELSRFKN....E..SLGMAVLHLSSVALQSER..SLEEV.AKEL...S.........F.MRCIPKSFSRQIQQNNYLTKLRIRGVFKQFVK.GFH..Q..HTISKGKLGPQDIMYKYLSTLENL....................................................
F7B2N9_HORSE/126-244                 .............SAILDLPVLEHLFAQ.HRND...LLSGR.LPVGLGLKEQG------....E..CLSLAVLDLARMAREQAQ..RPEEL.LKTV...S.........Y.KACLPPGLRDLIQGLSFVTRKRIRRTVRRALR.RVV..-..----ACQADRHSLMAW--------allkita.............................................
A0A091IV20_EGRGA/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQGYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
F6VBG6_HORSE/142-213                 ............m-QLLDSASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCRGV..PVEKV.AKKI...-.........-.--------------------------------.---..-..------------------------rcl.................................................
H0X195_OTOGA/126-245                 .............SAILDLPVLEHLFAQ.HRSD...LVNGH.LPVGLSLKEQG------....E..CLSLAVLDLARMVHEQAK..RPAEL.LKTI...S.........Y.KTCLPPALREMIQGLSFVTRRRIRRTVSRALR.RVA..-..----ACQADRHSLMAKYIMDLDRL....................................................
A0A2I2UMB9_FELCA/126-245             .............SAILDLPVLEHLFAQ.HRND...LVSGR.LAVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..QPEEL.LKTV...S.........Y.KACLPPDLRDLIQGLSFVTRKRIRRTVRRALG.RVT..-..----ACQADRHSLMAKYIMDLERL....................................................
G1RNJ0_NOMLE/141-266                 ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRHGI..PLEEV.AKKT...S.........F.KDCIPRSFRRHIRQHSALTRLRLRNVFRRFLR.DFQ..-..----PGRLSQQMVMVKYLATLERL....................................................
A0A0Q3QW93_AMAAE/125-244             .............SPVLDYPVIDYLFAQ.SRSD...FIGGR.MAVALSLPQQE------....E..CLGLAVLDMLRIAKEKHQ..SPSEV.FSHV...S.........Y.KSCIPAPLRCQIQQHSFLTRKRIRHRFSKSLR.KLG..-..----GCQPDXCCLKLKYLLDLERL....................................................
A0A286ZVG5_PIG/141-266               ............v-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFQN....E..SLGMAFLHLCQLALRHGV..PLEKV.AKKI...S.........F.KDCIPRSFRRQIRQHNALTRLRLRSIFRKFLR.AFQ..-..----PGCLSQQVVMVKYLATLERL....................................................
M3W7U9_FELCA/126-245                 .............SAILDLPVLEHLFAQ.HRND...LVSGR.LAVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..QPEEL.LKTV...S.........Y.KACLPPDLRDLIQGLSFVTRKRIRRTVRRALG.RVT..-..----ACQADRHSLMAKYIMDLERL....................................................
L5L284_PTEAL/155-280                 ...........mr--LLDPASFEYLFEQ.GKHE...FVNDV.ASLWDLSNEEEIHHFKN....E..SLGMAFLHLCHLAVCLGV..PLKKV.ARKI...S.........F.KDCIPRSFRQQIQQHNAFTQLRLWIIFHKFLW.AFQ..-..----PGHLSQQVIMVKYLATLERL....................................................
A0A1U7S0K0_ALLSI/138-268             .............SALLDRASFEYLFEQ.GKFE...FVNDV.ASLQDLATEQDLHRFKN....E..SLGMAVLHLSHLALRRGL..SLEEA.AKKC...S.........F.KDCIPWSFRRQIQQSSSLTRLRLRSVFRRFVQ.HFQ..R..HTVGAGRLTEQGVMYKYLATLESL....................................................
F1PIY7_CANLF/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A2D0RWX2_ICTPU/141-271             .............TPLLDAASLDYLFAQ.GQYD...FLRGL.APVRTPQSDMELHEIEN....E..CLGMAVLAITHHAKSNNL..PLSGS.GAET...S.........Y.KRFIPESLNRTIKQRSFLTRMRISNVFKNFLN.EFN..S..KTIRDSNITLYDLKVKYLSTLETL....................................................
F7BLF9_HORSE/1-86                    .............---------------.----...-----.-----------------....-..---MAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSMHDLKVKYLATLETL....................................................
A0A2K5JYU7_COLAP/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
U3IX13_ANAPL/82-212                  ............g-AVLDKASFEYLFEQ.GKSE...FINDV.ASLRDLQTEQEIQRFKN....E..SLGMAVLHLSHIAIKKGI..SLEEV.ARKY...S.........F.KDCIPRSFYRQIQQNNYLTKFRMKTVFKKFVQ.RFQ..R..HTVSAGKLTEQDIMYKYLATLEHL....................................................
H2TCV3_TAKRU/140-259                 .............SPVLDHSGIAYLFAQ.LRSD...FTTGE.AGLSPPLTNQD------....E..CLGLAVLDLWRLAKEKRQ..SVKDL.CKSV...S.........Y.KSCLPKSHRADIEKRNWVERYRIRNTLKHFLK.KIG..-..----NCPVDDCNLKLMYLTEL---agi.................................................
H2VE44_TAKRU/119-245                 .............TPLLDAASLDYLFYQ.GQHS...FHKGL.VPLRKSHSDAEQHEIEN....E..CLGMAVLAITHT---TNM..SVPG-.SHDI...S.........Y.KRFIPESLNRSIKQRSFMTRIRINNVFKKFLS.EFH..Q..RTIRDSNITPYDLKIKYLATLEGL....................................................
A0A1S3MPK9_SALSA/129-248             .............SAVLDYCVIDYLFAQ.SRSD...FVAGQ.AGVSPPLSVQE------....E..CLGLAVLDLWRLAKEHNQ..SVREV.CKNV...S.........Y.KSCLPETHRQEIQQLSRLARYRIRNTLKRFLK.KLG..-..----RCSVGERSLKLKYLMEL---agv.................................................
D2GV17_AILME/126-245                 .............SAILDLPVLEHLFAQ.HRND...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..QPEEL.LKTV...S.........Y.KVCLPPDLRDLIQGLSFVTRKRIRRTVRRALR.RVT..-..----ACQADRHSLMAKYIMDLERL....................................................
A0A091K588_COLST/76-201              .............TPILDASSLEYIFAQ.V---...--RGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAINKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVTPRDLKVKYLSTMETL....................................................
A0A0F8AHG9_LARCR/147-274             .............TPLLDAASLNYLFSQ.GQHD...FQKGV.VPLRISQSEAEQHEIEN....E..CLGMAVLAITHYDMNKDM..GTS--.-NEN...S.........Y.KRFIPESLNRNIKQRNFLTRIRISNVFKKFLN.EFN..R..RTVKDSNITPYDLKIKYLATLEGL....................................................
A0A1U7U068_TARSY/147-277             .............TPLLDANSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMRKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
W5M4D5_LEPOC/132-251                 .............TAVLDYSVIDYLFAQ.TRCD...LVAGQ.AGLSPPLSAQE------....E..CLGLAVLDLWRLAKESNK..SLKEI.CKKV...S.........Y.KSCLPETHRQEIQQLSRLARYRIRKTLKRFLR.RIG..-..----RCPVGSHSLKLKYLIELEA-v...................................................
G3H4C9_CRIGR/66-185                  .............SAILDLHVLEHLFAQ.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLAQMARERAQ..RPGEL.LKAV...S.........Y.KACLPPALRDLIQGLSFVTRRRIRRTVLQALR.RVV..-..----ACQADRCSLMAKYILALEX-x...................................................
M3VXL7_FELCA/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
F6SFF7_CIOIN/188-291                 ..........qep------SVFNYLFHQ.TRHD...FIQHG.---TWKQHKIDAKTFES....S..PLTLAVIDLLHLSFLLRK..NPKEV.LNAI...D.........V.SNLLPKSLQHNLDKQWFIEKYKWKFMAQKRLA.HLL..K..ET----------------------f...................................................
F1NQU4_CHICK/140-259                 .............SPVLDDLVMSYLFAQ.WRKD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAV.YNSV...S.........Y.KMFLPKCVRAKIQEYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
J9P769_CANLF/126-245                 .............SAILDLPVLEHLFAQ.HRND...LVSGR.FSVGLSLKEQD------....E..YLSLAVLDLARMAREQAQ..QPEEL.LKTV...S.........Y.KVCLPPDLRDLIQGLSFVTRKRIRRMVRRALR.RVT..-..----ACQADRHSLMAKYIMDLERL....................................................
A0A2D0R906_ICTPU/131-261             .............TALLDSQSLTYLYAQ.SQYD...FQSAS.VALRDFQSEEEAQHVEN....E..CLGMAVMAISHEAMGKNL..PAREL.AKKF...K.........Y.KNYIPVSLNQLISQRNLLIRLRISNVFRSFLE.EFN..D..NTVLNSNVSKHDLKVKYISTLETL....................................................
S7PNQ5_MYOBR/283-352                 ..dsfphrqstpp---------------.----...-----.-----------------....-..------------------..-----.--TH...S.........Y.KTCLPPGLRDLIQGLSFVTRRRIRRRVRQALL.RVA..-..----TCQADRHSLMAKYIMDLERL....................................................
A0A091NKY1_APAVI/1-95                .............---------------.----...-----.------------HEIEN....E..CLGMAVLAISHYAIKKDV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
F6V3I2_MONDO/137-267                 ............c-ALLDKASFEYLFEQ.GKFE...FVNDV.ASLWDLHSEAEIHHFKN....E..SLGMAVLHLSHLALQRGI..PLEEV.VRKT...S.........F.KDCIPRSFSRQIQQNNFLTKFRLRTVFQKFMR.RFH..L..QTVGPGHLSKQNIMFKYLATLEQL....................................................
L5K8D1_PTEAL/140-259                 ............a-PLLDDFVMSYLFAQ.WRHD...FLHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLDI.YSSV...S.........Y.KTFLPKCVRAKIQEYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
S7MWR8_MYOBR/162-292                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMIKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
G1LYZ3_AILME/146-271                 ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALCHGV..PLEKV.AKKI...S.........F.KDCIPRSFRQQIRRHNALTRLRLRNIFRRFVR.AFQ..-..----PGHVSQQVIMVKYLATLEQL....................................................
A0A091XF04_OPIHO/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDE..TPLAI.YNSV...S.........Y.KQFLPKCVRAKIQEYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A1U7SIM6_TARSY/185-310             ............m-QLLDSASFEYLFEQ.GKHE...FVNDV.ASLSELSSEEEIHHFKN....E..SLGMAFLHLCHLALHRGV..PLEEV.AKKI...S.........F.KDCIPRSFRLQIRQHSTLTRLRLRSMFRSFLR.AFQ..-..----PGRLSQQVVMVKYLATLERL....................................................
A0A0A0AT86_CHAVO/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A2I3MPX7_PAPAN/141-266             ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRRGV..PLEEV.AKKT...S.........F.KDCIPLSFRRQIRQHSALTRLRLRNVFRRFLQ.DFQ..-..----PDRLSQQMVMVKYLATLERL....................................................
W5L4W4_ASTMX/129-248                 ............c-AVLDYCVIDYLFAQ.SRSD...FVSGR.GGVNPPLGAMQ------....E..CLGLAVLDLWRQAKERNR..SPREV.CKTV...S.........Y.KSCLPKTHREDIQRMSRLARYQIRKTLKRFLQ.KLG..-..----QCSAGERSLKLKYLMELS--av..................................................
I3MAE0_ICTTR/126-245                 .............SAILDLPVLEHLFAQ.HRSD...LLSGR.LHVGLSLQEQG------....E..CLSLAVLDVARMACEQGQ..RPAQL.LKTV...S.........Y.KACLPPGLRDLIQGLSFVTRRRIRTTVRCALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
G3STB4_LOXAF/147-271                 ............q--FLDPASFEYIFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALHRGV..SLEEV.AKKI...S.........F.KDCIPRSFRSQIQQHNALTRLRLRSIFHKFLR.AFQ..-..----PSHLSQQLVMVKYLATLERL....................................................
A0A1A6H8C5_NEOLE/59-178              ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLAV.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
JAK1_DANRE/145-275                   .............TPLLDAASLDYLFAQ.GQYD...FLRGL.SPVRPTQTDEEHHEIEN....E..CLGMAVLAITHHAKSNNL..PLSGA.GAET...S.........Y.KRFIPDSLNRTIKQRNFLTRIRISNVFKNFLN.EFN..S..KTIQDSNIGLYDLKVKYLSTLETL....................................................
G3QSH5_GORGO/126-245                 .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRRRIRRTVRRALR.RVA..-..----ACQADRHSLMAKYIMDLERL....................................................
J9JIK9_PIG/142-261                   ............a-PLLDDFVMSYLFAQ.WRHD...FLYGW.VKIPVTHETQE------....E..CLGMAVLDMMRIAKEKDQ..TPLDI.YSSV...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
A0A087QSD3_APTFO/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
H3DL74_TETNG/147-273                 .............TPLLDAASLEYLFYQ.GQHS...FHKGL.VPVRKSHSDTEQHEIEN....E..CLGMAVLAITHTT---NV..GAPG-.SHDI...S.........Y.KRFIPETLNRSIKQRSFLTRIRINNVFKKFLS.EFH..Q..RTVRDSNITPYDLKIKYLATLEGL....................................................
M3ZMT4_XIPMA/146-265                 .............SPVMDDCVMAYLFAQ.WRSD...FLNGW.VHIPVSHESQE------....E..CLGMAVLDMMRLAKESNL..SPVDI.YNDT...S.........Y.KSFLPRCMRNRIQEYNLLTRKRIRYRFRRFIQ.QFS..-..----ECKATVCNLKLKYLMNLEML....................................................
H0X425_OTOGA/141-266                 ............v-QLLDPASFEYLFEQ.GKYE...FVNDV.VSLWELSSEEEIHHFKN....E..SLGMAFLHLCQLALHHGV..SLEEV.AKKI...S.........F.KDCIPCSFRRQIRQHNMLTRLRLRNVFRKFIK.AFQ..-..----PGVLSQQVVMVKYLATLERL....................................................
H3DDQ1_TETNG/27-146                  .............SPVFDDCVMSYLFSQ.WRND...FVNGF.VKIPSSHEIQE------....E..CLGMAVLDMTRTAKERQL..SPLDI.YHTM...S.........Y.KSFLPKEIRAQIQDCNFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTVRDLKLKYLISMESL....................................................
A0A0F8C2P5_LARCR/124-243             .............SPVLDDFVMSYLFSQ.WRND...FVNGL.VKIPNSHETQE------....E..CLGMAVLDMTRTAKEKHL..SPLDI.YHTI...S.........Y.KSFLPKDMRAQIEDCNFLTRKRIRFRFKRFIQ.QFS..-..----QCRTTARDLKLKYLISMESL....................................................
W5M4B2_LEPOC/139-258                 .............TAVLDYSVIDYLFAQ.TRCD...LVAGQ.AGLSPPLSAQE------....E..CLGLAVLDLWRLAKESNK..SLKEI.CKKV...S.........Y.KSCLPETHRQEIQQLSRLARYRIRKTLKRFLR.RIG..-..----RCPVGSHSLKLKYLIELEA-v...................................................
JAK3_RAT/126-245                     .............SAILDVHVLEHLFAQ.HRSD...LVSGR.LPVGLSLKDQG------....E..FLSLAVLDLAQMARKQAQ..RPGEL.LKSV...S.........Y.KACLPPSLRDLIQGQSFVTRRRIRRTVVQALA.PCS..-..----SLPSRPYALMAKYILDLERL....................................................
I3M8D2_ICTTR/142-261                 ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A093EPV8_GAVST/147-277             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKMV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDGSVSPRDLKVKYLSTMETL....................................................
G3PKW3_GASAC/135-265                 .............SPLFEITSLEYLFFQ.AKYE...FVNEM.VQMEDVQSEEEGSRLKN....E..SLGMAVLQLSHQAMLTGC..TLQDA.ADKV...S.........F.LHCIPRSFAKQISKDNFLTKLRIRRVFREFVR.TFQ..Q..HTVDKGRLGAQEIMYRYIATLEHL....................................................
B4L4A0_DROMO/128-233                 ............l-PVIDVHCHKYLYHQ.MRYD...MLHEE.IN--EIRYPEH----KD....K..VMGLAVMDMLIDKEEQQL..IAQDV.EK--...A.........Y.KSYLPRSLWR---AHRIFVRSKIRSTFRR---.---..-..------------------------lssdppnvdslkwhyvh...................................
A0A091I984_CALAN/146-276             .............TPILDANSLEYIFAQ.GQYD...FVKGL.APVRDAQNEQEGHEIEN....E..CLGMAVLAICHDAIKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKIIRQRNFLTRIRINNVFRHFLK.EFN..N..KTICNNTVSSRDLKVKYLSTMETL....................................................
A0A1S3G4P2_DIPOR/126-245             ............g-AVFDLRVLEHLFAQ.HRGD...LVAGR.LAVGLGLRDQG------....E..CLSLAVLDLARLCRERAQ..RPREL.LRTV...S.........Y.KACLPPGLRGLIQGLSFVTRKRIRRTVRRALR.RVA..-..----ASQADRHSLLAKYIMDLERL....................................................
K7E1N4_MONDO/137-267                 ............c-ALLDKASFEYLFEQ.GKFE...FVNDV.ASLWDLHSEAEIHHFKN....E..SLGMAVLHLSHLALQRGI..PLEEV.VRKT...S.........F.KDCIPRSFSRQIQQNNFLTKFRLRTVFQKFMR.RFH..L..QTVGPGHLSKQNIMFKYLATLEQL....................................................
M3XNR7_MUSPF/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
G1R1P8_NOMLE/126-226                 .............SAILDLPVLEHLFAQ.HRSD...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMAREQAQ..RPGEL.LKTV...S.........Y.KACLPPSLRDLIQGLSFVTRKRIRRTVR----.---..-..------------------------vlqpfcdf............................................
A0A0F8AEI9_LARCR/116-246             .............SPLLEITALEYLFSQ.AKYE...FVNEV.VQMEDVQSEEELSRFKN....E..SLGMAVLHLSHQAMQTGS..TLQDV.AKKV...S.........F.LRCIPRSFAKHISKDNFLTKIRIRRVFSDFVQ.TFQ..Q..HTVDKGRLGTHEIMYKYISTLEHL....................................................
I3MJ48_ICTTR/147-277                 .............TPLLDASSLEYLFAQ.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKV..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSPHDLKVKYLATLETL....................................................
A0A2K5KJN0_CERAT/141-266             ............m-QLLDPASFEYLFEQ.GKHE...FVNDV.ASLWELSSEEEIHHFKN....E..SLGMAFLHLCHLALRRGV..PLEEV.AKKT...S.........F.KDCIPLSFRRQIRQHSALTRLRLRNVFRRFLQ.DFQ..-..----PDRLSQQMVMVKYLATLERL....................................................
A0A2I3NI09_PAPAN/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
G3NVW0_GASAC/149-279                 .............TPLLDAASLDYLFAQ.GQHD...FQTGL.VPLRASSSEAEQHEIEN....E..CLGMAVLAITHYTTNMDM..TLTTA.ANES...S.........Y.KRFIPESLNRNIKQRNFLTRIRINNVFKKFLS.EFN..R..RTIKDSKITPYDLKIKYLATLEGL....................................................
A0A1S3ADN5_ERIEU/126-245             ............g-AFLDLPVLRHLFAQ.LRSD...LVSGH.LAMGLSLKEQG------....E..CLSLAVLDLACLARERGL..RPAEL.LRTI...S.........Y.KDCLPPSLRELIQGLSFVTRRRIRRTVERALH.KVV..-..----GCQAEAPALMAKFVMDLQRL....................................................
A0A2I2Y6E6_GORGO/142-261             ............a-PLLDDFVMSYLFAQ.WRHD...FVHGW.IKVPVTHETQE------....E..CLGMAVLDMMRIAKENDQ..TPLAI.YNSI...S.........Y.KTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQ.QFS..-..----QCKATARNLKLKYLINLETL....................................................
A0A091HKF2_BUCRH/141-260             .............SPVLDDLVMSYLFAQ.WRDD...FLNGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A1U8D4W6_ALLSI/79-209              .............SALLDRASFEYLFEQ.GKFE...FVNDV.ASLQDLATEQDLHRFKN....E..SLGMAVLHLSHLALRRGL..SLEEA.AKKC...S.........F.KDCIPWSFRRQIQQSSSLTRLRLRSVFRRFVQ.HFQ..R..HTVGAGRLTEQGVMYKYLATLESL....................................................
A0A1S3P9S9_SALSA/159-289             .............TPLLDSASLDYLFFQ.GQND...FQKGL.AVVRSQQSEAEQHEIEN....E..CLGMAVLAITHYAMTKEI..PLSTT.SNEI...S.........Y.KRFIPESLNRSIKQRNILTRLRINNVFKNFLN.EFN..S..RTMLESNITLYDLKIKYLSTLEGL....................................................
L5LC09_MYODS/92-211                  .............SAILDLPVLEYLFAQ.HRND...LVSGR.LPVGLSLKEQG------....E..CLSLAVLDLARMACEQAQ..QPEDL.LKTV...S.........Y.KTCLPPGLRDLIQGLSFVTRRRIRRRVRQALL.RVA..-..----TCQADRHSLMAKYIMDLERL....................................................
A0A1S3KQJ9_SALSA/26-145              .............SPVLDDTVMSYLFAQ.WRSD...FVDGW.VSIPVNHEAQE------....E..CLGMAVLDMMRMAKESSQ..APVDI.FNDT...S.........Y.KSFLPKDIRARIQEYHFVTRKRIRHRFKKFIQ.QFC..-..----QCNATARDLKLKYLANLEML....................................................
H0Z3Y5_TAEGU/141-260                 .............SPVLDDLVMSYLFAQ.WRTD...FLDGW.VQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPMAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
G3SSY6_LOXAF/149-274                 .......nliavl-----------LFLV.GQYD...LVKCL.APIRDPKTEQDGHDIEN....E..CLGMAVLAISHYAMMKKM..QLPEL.PKDI...S.........Y.KRYIPETLNKSIRQRNLLTRMRINNVFKDFLK.EFN..N..KTICDSSVSTHDLKVKYLATLETL....................................................
A0A091R6W6_MERNU/147-277             .............TPILDANSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIKKNV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSNVSPRDLKVKYLSTMETL....................................................
D3ZD03_RAT/146-271                   ............v-QLLDSASFEYLFEQ.GKHE...FMNDV.VSLRDLSSEEEIHHFKN....E..SLGMAFLHLCHLALNRGV..PLEEM.AREI...S.........F.KNCIPHSFRQHIRQHNVLTRLRLRRVFRRFLQ.AFQ..-..----PGHLSQQVVMVKYLATLERL....................................................
A0A1D5PK82_CHICK/1-38                .............---------------.----...-----.-----------------....-..------------------..-----.----...-.........-.----------------------MKNVFRKFVR.RFQ..R..HTVGAGTLTEEDVMFKYLATLELL....................................................
A0A087V8Q7_BALRE/67-186              .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKEKDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
H2LLN7_ORYLA/133-263                 .............STLLDITSLEYLFAQ.AKHE...FVNEV.VEMKEVQNEEERSQFKN....E..SLGMAVLHLSHLAIETNS..TLPAV.ARKV...S.........F.LQCIPRSFAKNISNDNFLTKIRIRTVFAEFVR.SFQ..Q..HTVDSRKVTPQEIMYKYISTLEQL....................................................
M3Y0T4_MUSPF/140-259                 .............TPLLDDFVMAYLFAQ.WRHD...FLHGW.IKIPVTHETQE------....E..CLGMAVLDMMRLAKEKDQ..TPLDI.YSSI...S.........Y.KTFLPKCVRAKIQDYHILTRKRIRYRFRRFIE.QFS..-..----HCKATARNLKLKYLINLETL....................................................
U3IAY8_ANAPL/142-261                 .............SPVLDDLVMSYLFAQ.WRDD...FLDGW.IQMPVTHETQE------....E..CLGMAVLDMMRVAKERDQ..TPLAI.YNSV...S.........Y.KMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQ.QFG..-..----QCKATARNLKLKYLINLETL....................................................
A0A091GNU7_BUCRH/148-278             .............TPILDASSLEYIFAQ.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAIEKDV..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDTKVSPRDLKVKYLSTMETL....................................................
U3IXD0_ANAPL/1-120                   ............l------------LVK.GQYD...LVKGL.APIRDPKNDQEVHEIEN....E..CLGMAVLAISHYAINKKL..KLPEL.PKDI...S.........Y.KHYIPETLNKTIRQRNFLTRIRINNVFKHFLK.EFN..N..KTICDSSVSPRDLKVKYLSTMETL....................................................
#=GC SS_cons                         ............BB-SCEHHHHHHHHHH.HHHH...HHTTS.S-CGGSCSHHHHHHHHH....H..HHHHHHHHHHHHHHHTT-..SHHHH.HCCS...-.........G.GGGS-HHHHHHHHTS-HHHHHHHHHHHHHHHH.HCC..H..THHHTTT--HHHHHHHHHHHHHHH....................................................
#=GC seq_cons                        .............oPlLDssshcYLFAQ.t+pD...FVpsh.ssl.sspppQE..........E..CLGMAVLcls+hAhc+s...s..-l.hcsl...S.........Y.KphlPcslRppIpphshLTRhRIRphF++Flp.pFs.........pspsos+sLKlKYLhsLEpL....................................................
//
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