#=GF ID FimH_man-bind
#=GF AC PF09160.12
#=GF DE FimH, mannose binding
#=GF AU Sammut SJ;0000-0003-4472-904X
#=GF SE pdb_1klf
#=GF GA 25.00 25.00;
#=GF TC 25.20 26.30;
#=GF NC 20.30 21.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF CL CL0204
#=GF RN [1]
#=GF RM 12010488
#=GF RT Structural basis of tropism of Escherichia coli to the bladder
#=GF RT during urinary tract infection.
#=GF RA Hung CS, Bouckaert J, Hung D, Pinkner J, Widberg C, DeFusco A,
#=GF RA Auguste CG, Strouse R, Langermann S, Waksman G, Hultgren SJ;
#=GF RL Mol Microbiol. 2002;44:903-915.
#=GF DR INTERPRO; IPR015243;
#=GF DR SCOP; 1klf; fa;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Members of this family adopt a secondary structure consisting of
#=GF CC a beta sandwich, with nine strands arranged in two sheets in a
#=GF CC Greek key topology. They are predominantly found in bacterial
#=GF CC mannose-specific adhesins, since they are capable of binding to
#=GF CC D-mannose [1].
#=GF SQ 50
#=GS D4DZU5_SEROD/16-165 AC D4DZU5.1
#=GS K8WEF5_9GAMM/1-95 AC K8WEF5.1
#=GS A0A0J5NKQ8_PLUGE/24-170 AC A0A0J5NKQ8.1
#=GS A0A6I4L2T3_9ENTR/24-168 AC A0A6I4L2T3.1
#=GS W0LFI5_9GAMM/30-173 AC W0LFI5.1
#=GS A0A0F7HCS2_SERFO/30-173 AC A0A0F7HCS2.1
#=GS A0A248KHK6_9ENTR/25-169 AC A0A248KHK6.1
#=GS D2TJL9_CITRI/25-170 AC D2TJL9.1
#=GS J2LRJ1_KLEPN/26-170 AC J2LRJ1.1
#=GS FIMH_ECOLI/24-168 AC P08191.2
#=GS FIMH_ECOLI/24-168 DR PDB; 6YHW B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 3ZL1 B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KIU L; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AVK B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AUY A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5AB1 B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 3RFZ A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AVJ B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4W B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KIU D; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1QUN D; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1UWF A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6GTY C; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1QUN J; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2S F; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XOB G; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5JCR B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KLF H; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2S H; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XOB A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KLF D; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XOA G; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4X50 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4V A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4X A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4V C; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AUJ A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4W A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5FWR G; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4U B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AUU A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2S B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5MUC B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1QUN H; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XOB C; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4X5R C; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4V B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4CST A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5F2F A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AVH B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AV0 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5MCA A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5FWR H; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1TR7 B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AV5 C; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4X5Q A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 3ZL1 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2R B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2S D; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KIU N; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6GTY D; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XOB E; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AV5 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KIU P; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5CGB B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4T B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5AB1 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6YHW A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4X5P A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2S G; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4X5R A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4LOV A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KIU B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5FWR C; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XOD A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2R A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5FWR A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4X50 B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2S C; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 3RFZ D; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XO8 B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AVJ A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5FWR B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4J3O H; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5ABZ B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4CSS A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2S A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AVK A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4X B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KLF N; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5JCQ B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AUY B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5JCR A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KLF P; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4ATT A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6GTX A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5FX3 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6E15 H; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1QUN L; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5FS5 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AV5 D; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AV5 B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AVI B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AUU B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AV4 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 3ZL2 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AVH A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XO8 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2S I; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1TR7 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AVI A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1QUN B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6GTY A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5FWR E; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6GTX C; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 2VCO A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4U A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5MTS B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5FWR D; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6G2S E; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4T A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4Y A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KLF J; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XOA A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XOA E; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4Y B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5F3F A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XO9 A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6GTX D; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6GTY B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KLF L; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KIU J; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1QUN F; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5L4W C; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1QUN P; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5CGB A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5FWR F; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5MUC A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6GTY E; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KLF B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KIU H; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 2VCO B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4XOA C; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KIU F; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1QUN N; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5ABZ A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5MTS A; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6E14 H; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 6GTX B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 1KLF F; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4AV0 B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 4X5R B; 3-147;
#=GS FIMH_ECOLI/24-168 DR PDB; 5JCQ A; 3-147;
#=GS A0A0J8YTF1_9GAMM/23-167 AC A0A0J8YTF1.1
#=GS Q1ZU85_PHOAS/22-172 AC Q1ZU85.1
#=GS Q8XBA6_ECO57/24-168 AC Q8XBA6.1
#=GS A0A348HGN6_9GAMM/18-162 AC A0A348HGN6.1
#=GS K8W5I6_9GAMM/1-98 AC K8W5I6.1
#=GS A0A378EEZ3_KLEPR/26-170 AC A0A378EEZ3.1
#=GS A0A514EVX1_9ENTR/32-184 AC A0A514EVX1.1
#=GS B2VGL4_ERWT9/32-181 AC B2VGL4.1
#=GS A0A198GHY6_9GAMM/25-170 AC A0A198GHY6.1
#=GS W0L8D6_9GAMM/29-179 AC W0L8D6.1
#=GS B2VEY7_ERWT9/28-172 AC B2VEY7.1
#=GS A6TDM0_KLEP7/25-169 AC A6TDM0.1
#=GS A0A6I4LSG3_9ENTR/25-169 AC A0A6I4LSG3.1
#=GS Q32FX7_SHIDS/6-92 AC Q32FX7.1
#=GS A0A095UYJ3_9GAMM/25-167 AC A0A095UYJ3.1
#=GS A0A085JND3_9GAMM/26-169 AC A0A085JND3.1
#=GS A8AMS7_CITK8/25-168 AC A8AMS7.1
#=GS A0A0H2UZE2_SHIFL/1-112 AC A0A0H2UZE2.1
#=GS A0A0H3H2I8_KLEPH/26-170 AC A0A0H3H2I8.1
#=GS A0A0H2W153_SHIFL/24-168 AC A0A0H2W153.1
#=GS A0A1B7JTX7_9GAMM/31-180 AC A0A1B7JTX7.1
#=GS A0A1E7Z0K3_9GAMM/23-167 AC A0A1E7Z0K3.1
#=GS YDEQ_ECOLI/27-171 AC P77588.1
#=GS YDEQ_ECOLI/27-171 DR PDB; 6MAP B; 3-147;
#=GS YDEQ_ECOLI/27-171 DR PDB; 6MAW A; 3-147;
#=GS YDEQ_ECOLI/27-171 DR PDB; 6MAQ B; 3-147;
#=GS A0A0A2VY98_BEABA/20-162 AC A0A0A2VY98.1
#=GS A0A0L7THN9_9GAMM/40-184 AC A0A0L7THN9.1
#=GS E9CQK6_9GAMM/1-77 AC E9CQK6.1
#=GS A0A336Q1W3_CITKO/25-168 AC A0A336Q1W3.1
#=GS Q8XAX2_ECO57/27-171 AC Q8XAX2.1
#=GS A0A0J8YKK0_9GAMM/25-169 AC A0A0J8YKK0.1
#=GS A0A514EM02_9ENTR/25-169 AC A0A514EM02.1
#=GS A0A348HGN5_9GAMM/49-195 AC A0A348HGN5.1
#=GS A0A6I4L0G7_9ENTR/27-171 AC A0A6I4L0G7.1
#=GS K8WLZ7_9GAMM/22-176 AC K8WLZ7.1
#=GS A0A089Q9V9_9ENTR/18-161 AC A0A089Q9V9.1
#=GS A0A1I4X1B9_9ENTR/37-181 AC A0A1I4X1B9.1
#=GS A0A085JP12_9GAMM/30-173 AC A0A085JP12.1
#=GS A0A495RCD0_9GAMM/22-174 AC A0A495RCD0.1
#=GS A0A2G8E182_9GAMM/28-179 AC A0A2G8E182.1
#=GS A0A198GCC4_9GAMM/29-180 AC A0A198GCC4.1
#=GS W1EPQ2_KLEPN/8-112 AC W1EPQ2.1
D4DZU5_SEROD/16-165 .........CRTSDGGLIPP..GGSTTpvDVRVRIGPQLSYGKNEI...VNVS-...QVTCKND..VSSWTdylkTDSPAL.S.MN.SAIFGGI.G-...--SGMTINGRDY..PSPVSS..G.ISVVTL...TNLNSQSIAIR.V.Y.IVLNrFPT.PD..IKINKGDVIGQINFSQTND....RPN--.....--...-----cpqcgpyrwr.....
K8WEF5_9GAMM/1-95 ........m-----------..-----..-----------------...-----...-------..-----....------.L.SG.SAYSGVL.AN...FRGSLRYYGSSY..PFPLTS..P.THQHSF...PSGNYTPWNTQ.L.Y.LTPI.SSA.GG..VVLNKGARFATLVMYQVGSd..iIGGGN....vHT..vTFTW-h..............
A0A0J5NKQ8_PLUGE/24-170 .........CKILSTGQM-V..QTGSA..NLYVNLTPQIGVGQNLI...VDLTQ...EIKCKNDsaPPDID....VDHLKL.L.SG.SAYQGAL.DN...FSGAVYWVGKYY..PIPLTA..N.TPYYSI...SNTSYAPLPLK.L.Y.LTPL.GAA.GG..KLIRSGELIAVLSVYKIAT....FDGGY.....PT...TFTWN...............
A0A6I4L2T3_9ENTR/24-168 .........CKTANGTAIPI..GGGSA..NVYVNLAPAVNVGQNLV...VDLST...QIFCHND..YPETI....TDYVTL.Q.RG.SAYGGVL.SN...FSGTVKYSGSSY..PFPTTS..E.TPRVVY...NSRTDKPWPVA.L.Y.LTPV.SSA.GG..VAIKAGSLIAVLILRQTNN....YNSDD.....F-...QFVWN...............
W0LFI5_9GAMM/30-173 .........CQTAAGATIPI..GGGNA..DVYVTLSPQIGVGQNLI...VDLST...QISCRND..FPQTI....KDFVSL.Q.AG.SAYGGVL.AN...FRGSFVYGGISY..PFPTTN..E.THSIEF...KTTTMTPWPAV.L.Y.LTPI.SSA.GG..VAITSGSLIAMLNMHQTND....KGESH.....P-...-YIWR...............
A0A0F7HCS2_SERFO/30-173 .........CRTAAGATIPI..GGGSA..NVFVDLTPQIGVGQNLI...VDLSR...QISCRND..FPENR....IDYVSL.Q.RG.SAYGGVL.AS...FTGSFVYDGTSY..PFPTTS..E.TKSVVY...RTTTMTPWPAV.L.Y.LTPI.STA.GG..VAITSGSLIAVLNMHQTNN....VGESH.....S-...-YIWN...............
A0A248KHK6_9ENTR/25-169 .........CRTASGTTIPI..GGGSA..NVYVDLAPEVNVGQNLV...VDLST...QIFCHND..YPETM....TDYVTL.Q.RG.SAYGGVL.SS...FSGTVKYNGSSY..PFPTTT..E.TARLIY...NSKTDKPWPTM.L.Y.LTPI.SSA.GG..VAISAGTLIAVLILRQTNN....KNNDD.....F-...QFVWN...............
D2TJL9_CITRI/25-170 .......ct---TTGGDIGI..GGGDA..HIYVDLTPQVNVGQNLL...IDLST...QIFCHND..YPDSM....TDFVTL.T.VQ.SVYDGVL.KS...FTGTLRYDGTTY..PFPLQN..E.TREIRY...TSKKPTPWPVA.L.Y.LTPV.STA.GG..VVISAGTQIATLDLRQTNN....VNSDN.....FT...-----fkfyih.........
J2LRJ1_KLEPN/26-170 .........CKTATGATIPI..GGGSA..NVYVNLTPAVNVGQNLV...VDLST...QIFCHND..YPETI....TDYVTL.Q.RG.SAYGGVL.SS...FSGTVKYNGTSY..PFPTTT..E.TARVIY...DSRTDKPWPAV.L.Y.LTPV.STA.GG..VAITAGSLIAVLILHQTNN....YNSDS.....F-...QFIWN...............
FIMH_ECOLI/24-168 .........CKTANGTAIPI..GGGSA..NVYVNLAPVVNVGQNLV...VDLST...QIFCHND..YPETI....TDYVTL.Q.RG.SAYGGVL.SN...FSGTVKYSGSSY..PFPTTS..E.TPRVVY...NSRTDKPWPVA.L.Y.LTPV.SSA.GG..VAIKAGSLIAVLILRQTNN....YNSDD.....F-...QFVWN...............
#=GR FIMH_ECOLI/24-168 SS .........EEETTSEEEBT..TSEEE..EEEE---SBEETTSEEE...EEGGG...TEEEE-S..STTT-....-EEEEE.E.EE.EEEHHHH.HH...EEEEEEETTEEE..EESBSS..-.---EEE...-SSS-EE--EE.E.E.EEES.TTS.SE..EEE-TTSEEEEEEEEEEES....SSS-E.....E-...EEEEE...............
A0A0J8YTF1_9GAMM/23-167 .........CKTAAGATIPI..GGGNA..NVYVNLTPQVQSGGNLV...VDLAN...SIFCHND..YPASI....TDYVTL.A.SG.SSFNGVL.KN...FKGSVIYNGQNY..SFPTTR..E.TSRVLY...RSKSDTAWPAR.L.L.LTPI.STA.EG..VVVNSGSLIASLVLHQTNN....VGNDS.....Y-...YYTWN...............
Q1ZU85_PHOAS/22-172 .........CRVRATGQIISyrGAKQA..DVTVSLVPKIGAHENII...IDFSQgssEIDCKDD..LPQSL....IDIFWP.T.EG.NEFIAPE.KI...KNGSLDWWGKRY..SFPMQA..QpGNSHEI...SDGAYHPLDVK.F.T.LSPT.SNA.NG..VIIKKGQPIGYFEYHQKNR....P----.....--...-----akrskmknlr.....
Q8XBA6_ECO57/24-168 .........CKTANGTAIPI..GGGSA..NVYVNLAPAVNVGQNLV...VDLST...QIFCHND..YPETI....TDYVTL.Q.RG.SAYGGVL.SN...FSGTVKYSGSSY..PFPTTS..E.TPRVVY...NSRTDKPWPVA.L.Y.LTPV.SSA.GG..VAIKAGSLIAVLILRQTKN....YNSDD.....F-...QFVWN...............
A0A348HGN6_9GAMM/18-162 ....aglag-------TTIQ..GSSNA..TIPVPVQDTAETGQVNI...IDLAA...YIECKND..NPGTY....TDHMDM.Q.RA.ST---VLsNN...FDVRVKANGVEY..TVPFSG..S.ATVLHLpkgGSGSYAPIPLQ.I.Y.YYMKeIPG.ER..VAIKKGQVIGSIQAHKYSI....PAGGA.....P-...TFTW-t..............
K8W5I6_9GAMM/1-98 ........m-----------..-----..-----------------...-----...-------..-----....---VNM.V.NG.SAFSGLL.AK...FNGSIRYYGASY..PFPLNS..P.THQKSF...PLGNYTAWSAQ.I.Y.LTPI.STA.GG..VVINKGTHFATLVMYQAGTn..iNGGGDm...sTA...TFTWK...............
A0A378EEZ3_KLEPR/26-170 .........CKTATGATIPI..GGGSA..NVYVNLTPAVNVGQNLV...VDLST...QIFCHND..YPETI....TDYVTL.Q.RG.SAYGGVL.SS...FSGTVKYNGTSY..PFPTTT..E.TARVIY...DSRTDKPWPAV.L.Y.LTPV.STA.GG..VAITAGSLIAVLILHQTNN....YNSDS.....F-...QFIWN...............
A0A514EVX1_9ENTR/32-184 ..cmtsagp--------IYD..GGGSA..NVYVNLSPQLSSGQVLV...VNLGD...SISCRND..DPANF....WDYARI.E.AG.SSYSGVL.NS...FHGTLSYYGTSY..NLPLSS..P.TSYFQY...TWGQYQPLNLM.M.Y.LTPIgNNV.SG..TSIKQGDLITVLNLFKQAY....YSTG-.....--...-----sgaghssgntsmtwy
B2VGL4_ERWT9/32-181 .........CRNKQTGQS-L..KGGNS..SVTVPISRTLTFGEQVV...FDIGQ...YYECKND..NPGTY....SDYMET.Q.AN.ASSTTLP.TA...FDTGALINGGKY..DFPLPQvnV.FTLPKG...GDSNYHNVPIQ.V.Y.YSMK.DTP.GQ.lVKISKGQTLATLQLHKYAT....TTGGPq...dPQ...DFTWN...............
A0A198GHY6_9GAMM/25-170 .........CKVDGGQE--I..GSGNH..NIYVTLGPDVQIGRNLI...VDLSQ...HLSCYNS..YDNYS...dIDHVNL.E.PG.TRLTGPL.NR...FTGSIYWNGSTY..PLPLNT..T.TSVLHI...AEPYPQPMPMK.L.Y.LTPLnSAA.NG..VLVQAGSAIAQIKMYKIAD....LNGGD.....PR...FFTWN...............
W0L8D6_9GAMM/29-179 .......ds--TGNTLNSAS..GTATA..TVYVNLQPSITASQNLV...VDLSN...SIFCKND..NPTVR....NDHVSL.L.NG.SAYGGVL.SN...FNGTVEYYGSSY..PFPLRS..A.TSSKNF...TSGTYTKWDAK.L.Y.LTPLsSAA.SG..VVVKKNSQFASLVMFQRGSn..iVGGGN....vHT..aTFTWN...............
B2VEY7_ERWT9/28-172 .........CRTAGGVEIPI..GGGSA..NVYVNLTPSVGIGQNLV...VDLAT...QIACRND..YPSTH....TDYVSL.L.QG.SAYGGAL.KN...FKGSIIYSDSTY..PFPTTS..E.TKILTY...KSKTETPWPTK.L.Y.LTAIgSAA.DG..VAIKAGTLVAILNMHQTNN....YNESN.....S-...-YVWN...............
A6TDM0_KLEP7/25-169 .........CKTATGATIPI..GGGSA..NVYVNLTPAVNVGQNLV...VDLST...QIFCHND..YPETI....TDYVTL.Q.RG.SAYGGVL.SS...FSGTVKYNGTSY..PFPTTT..E.TARVIY...DSRTDKPWPAV.L.Y.LTPV.STA.GG..VAITAGSLIAVLILHQTNN....YNSDS.....F-...QFIWN...............
A0A6I4LSG3_9ENTR/25-169 .........CKTATGATIPI..GGGSA..NVYVNLTPAVNVGQNLV...VDLST...QIFCHND..YPETI....TDYVTL.Q.RG.SAYGGVL.SS...FSGTVKYNGTSY..PFPTTT..E.TARVVY...DSRTDKPWPTV.L.Y.LTPV.STA.GG..VAITAGSLIAVLILHQTNN....YNSDS.....F-...QFIWN...............
Q32FX7_SHIDS/6-92 ..stnwkhh-----------..-----..-----------------...-----...-------..-----....------.-.--.-------.QS...YKGSLYWNNVTY..PFPLTT..N.TNVLDI...GDKTPMPLPLK.L.Y.ITPV.GAA.GG..VVIKAGEVIARIHMYKIAT....LGSGN.....PR...NFTWN...............
A0A095UYJ3_9GAMM/25-167 ........c-QA-NGTSI-S..GSGTV..TVPVTLAPSVQSTENLV...VNLGN...SIQCKND..LPSVY....KDPIRV.G.TA.SAYAGAL.SA...FTGSITYNGDTY..SFPLPS..P.TSWVPT...PNGTYAPWNTI.L.Y.LTPT.GSA.SG..VVIQAGQIFATLQLQKEGN....PGQVS.....Q-...TITWN...............
A0A085JND3_9GAMM/26-169 .........CKTAAGVTVPA..GGGDA..NVYVTLTPSVGASSNLV...VDLSQ...SITCNDE..YPPTY....IDYVSL.Q.SG.SAFGGLL.SS...FSGTVDYNGTSY..AFPTTS..E.TAKVTY...NSKSFKSWPVK.L.N.LTPI.STA.GG..VVISSGSLIASLVLHQTNN....FSSSA.....S-...-YVWN...............
A8AMS7_CITK8/25-168 .........CKVNDTGQT-M..TSGSA..NVYVNLTPSVGVGQNLV...VDLSS...SVSCKND.sSGGSI....IDYINL.T.SG.SAFGGAL.AA...FTGSVYWAGNTY..PLPMNG..N.SSVYTI...THTDYLGLPLR.M.Y.LTAT.GAA.GG..VVINSGELIAQLNMHKVAS....--DGN.....PN...NFIWN...............
A0A0H2UZE2_SHIFL/1-112 .........-----------..-----..-----------------...--MSQ...HISCWND..YGGWY...dTDHINL.V.QG.SAFAGSL.QS...YKGSLYWNNVTY..PFPLTT..N.TNVLDI...GDKTPMPLPLK.L.Y.ITPV.GAA.GG..VVIKAGEVIARIHMYKIAT....LGSGN.....PR...NFTWN...............
A0A0H3H2I8_KLEPH/26-170 .........CKTATGATIPI..GGGSA..NVYVNLTPAVNVGQNLV...VDLST...QIFCHND..YPETI....TDYVTL.Q.RG.SAYGGVL.SS...FSGTVKYNGTSY..PFPTTT..E.TARVIY...DSRTDKPWPAV.L.Y.LTPV.STA.GG..VAITAGSLIAVLILHQTNN....YNSDS.....F-...QFIWN...............
A0A0H2W153_SHIFL/24-168 .........CKTANGTAIPI..GGGSA..NVYVNLAPVVNVGQNLV...VDLST...QIFCHND..YPETI....TDYVTL.Q.RG.SAYGGVL.SN...FSGTVKYSGSSY..PFPTTS..E.TPRVVY...NSRTDKPWPVA.L.Y.LTPV.SSA.GG..VAIKAGSLIAVLILRQTNN....YNSDD.....F-...QFVWN...............
A0A1B7JTX7_9GAMM/31-180 .......ds--TGNVLNSAS..GTATA..NVYVNLQPSVQAGQNLV...VDLSQ...SIYCKND..SPAIR....KDLVSM.I.RG.SAYGGVL.SK...FTGSLRYYGSSY..SFPLTS..P.THQQNF...SSGSYVPWNTQ.L.Y.LTPI.SAA.GG..VVINRGTLFASLVMYQIGSd..iPGGGN....iHT..aTFTWN...............
A0A1E7Z0K3_9GAMM/23-167 .krdgkpfd---------AV..GQRNI..DVTVNLSPEIIIGDVVV...FDLSD...TFTCRNT..MPKTY....VDYMLL.-.NS.ETYQTSLdES...FSSGLEVNGERY..LNPINS..A.ITVFKL...RDGNWHDLQVK.A.F.YQLMnSPG.RG..VFIKAGTLVASMQMYKWSA....-----.....--...-----paggvftanwr....
YDEQ_ECOLI/27-171 .........CNVDGGSS--I..GAGTT..SVYVNLDPVIQPGQNLV...VDLSQ...HISCWND..YGGWY...dTDHINL.V.QG.SAFAGSL.QS...YKGSLYWNNVTY..PFPLTT..N.TNVLDI...GDKTPMPLPLK.L.Y.ITPV.GAA.GG..VVIKAGEVIARIHMYKIAT....LGSGN.....PR...NFTWN...............
#=GR YDEQ_ECOLI/27-171 SS .........EEETT-S---B..SSEEE..EEEE---SB--TT--EE...EEGGG...TEEEE-S..S-TTT...T-EEEEE.-.TT.-EE-GGG.TT...SEEEEEETTEEE..EES-SS..-.---EEE...--SS-EE--EE.E.E.EE--.S-T.TE..EEE-TTSEEEEEEEEEE-S....STT--.....-E...EEEEE...............
A0A0A2VY98_BEABA/20-162 ....cqslg-------TTIS..GSGTV..TVRVNLVPSISAGQNLV...VDLSQ...SIQCKND..APSVY....LDPVRI.R.SG.SAYQGVL.SA...FRGTLGYFGVQY..PFPTTT..E.TAWVNH...TWGDYRGWQAV.L.Y.LTPI.STA.SG..VVVKANTMIAQLILEKEDS....LNGNR.....Q-...IINWN...............
A0A0L7THN9_9GAMM/40-184 ..krdgkaf--------DAV..GQRNI..DVTVNLSPEIMIGDVVI...FDLAD...YFTCMNT..IPNRY....VDYMRL.N.AG.SYNTTLD.AS...FNSGLEIKGQRY..LNPINS..S.VNVFEL...RDGNWHDLEVKaF.Y.QLKN.SPA.KG..VYIKAGAVVASMQFYKWS-....-----.....--...-----vpaggvftanwr...
E9CQK6_9GAMM/1-77 ......ilk-----------..-GGDS..SVTVPISRTVTPGEQVI...IDIGK...YYECKND..IPRYY....NDYMYT.Q.DH.ASSTTLP.PE...FETGAYINGGKY..------..-.------...-----------.-.-.----.---.--..-------------------....-----.....--...-----dpvpns.........
A0A336Q1W3_CITKO/25-168 .........CKVNDTGQT-M..TSGSA..NVYVNLTPSVGVGQNLV...VDLSS...SVSCKND.sSGGSI....IDYINL.T.SG.SAFGGAL.AA...FTGSVYWAGNTY..PLPMNG..N.SSVYTI...THTDYRGLPLR.M.Y.LTAT.GAA.GG..VVINSGELIAQLNMHKVAS....--DGN.....PN...NFIWN...............
Q8XAX2_ECO57/27-171 .........CNVDGGSS--I..GAGTT..SVYVNLDPVIQPGQNLV...VDLSQ...HISCWND..YGGWY...dTDHINL.V.QG.SAFAGSL.QS...YKGSLYWNNVTY..PFPLTT..N.TNVLDI...GDKTPMPLPLK.L.Y.ITPV.GAA.GG..VVIKAGEVIARIHMYKIAT....LGSGN.....PR...NFTWN...............
A0A0J8YKK0_9GAMM/25-169 .krdgkpfn---------AV..GQRNI..DITVNLSPEIIIGDVVV...FDLAN...YFTCKNE..LPNSY....VDYMRL.N.SG.TYQTSLD.ES...FSSGLEVNGTRY..LNPINS..P.ITVFEL...RDGNWHDLQVK.AfY.QLKN.SPG.RG..VFIKAGTVVASMQMYKWSA....-----.....--...-----paggvftanwr....
A0A514EM02_9ENTR/25-169 .........CKTATGATIPI..GGGSA..NVYVNLTPAVNVGQNLV...VDLST...QIFCHND..YPQTI....TDYVTL.Q.RG.SAYGGVL.SS...FSGTVKYNGTSY..PFPTTT..E.TSRVIY...NSTADKPWPTV.L.Y.LTPI.STA.GG..IAIASGSLIAVLILHQTNN....YNGDS.....Y-...QFVWN...............
A0A348HGN5_9GAMM/49-195 ..apnglal-------QVIK..GNSNA..TIQVPVSNTAETGQTNI...IDLSS...YIECKND..IPQSY....SDYMDL.Q.QA.TTI--LS.NN...FDVKVKARSNEY..SVPFSG..N.ANILTLprgGSGSYAPIPLQ.I.Y.YYMKeIPG.EK..VAIKKGQTIGAIRAHHHSI....PVEGD.....Y-...IFTWN...............
A0A6I4L0G7_9ENTR/27-171 .........CNVDGGSS--I..GAGTT..SVYVNLDPVIQPGQNLV...VDLSQ...HISCWND..YGGWY...dTDHINL.V.QG.SAFAGSL.QS...YKGSLYWNNVTY..PFPLTT..N.TNVLDI...GDKTPMPLPLK.L.Y.ITPV.GAA.GG..VVIKAGEVIARIHMYKIAT....LGSGN.....PR...NFTWN...............
K8WLZ7_9GAMM/22-176 .........CKTNAGQEVSS..GTQSI..N-NIPIDNDIFAVPNRInefANVND...YMTCRNE..LPSAY....VDYLNL.Q.S-.MTLGPVL.QSnpdLKAGVSVRGVRY..LAPFSG..R.DIQIFR...LTQSSESLQIK.L.Y.IQVNhKPT.PS..VLIKKGDLLMTLGLQKYAT...rVRSNN.....PIdflNFTWK...............
A0A089Q9V9_9ENTR/18-161 ....ayscn-------SIGW..NGGDA..DVNVNVSPDVNTGRNKI...VDLRS...QISCKND.sVDGGW....VDSMWLaS.NGmSLNSAIF.KD...LKGGVIISGKVY..PEPVP-..E.VEIFSL...NAQETKSLPVE.L.Y.FELT.SMG.KS..LQIRRGDRLAQIKFIQRNN....HGAQN.....Y-...-YIW-y..............
A0A1I4X1B9_9ENTR/37-181 .........CRTAAGAEIPI..GGGSA..DVYVTLAPSVGVGQNLV...VDLST...QISCRND..YPDTY....IDYVSL.M.SG.SAYGGAL.EN...FKGSIAYSDRTY..PFPTTS..E.TIKLTY...RSRTLTPWPTK.L.Y.LTAL.GNAgSG..VAIQGGSLIAKLNMSQTNN....YGDFN.....T-...-YVW-y..............
A0A085JP12_9GAMM/30-173 ........c-QA-NGTTI-N..GSGTV..TVPVTLTPSLGTTQNLV...INLGS...SIQCKND..APKQY....TDPIRV.G.TA.SAYAGAL.SS...FTGSITYNNSTY..AFPLSS..P.TPYVPT...TSGSYVAWNTI.L.Y.LSPT.GAA.SG..VVIQAGQIFASLSLQKENT....STGGV.....SQ...TIIWN...............
A0A495RCD0_9GAMM/22-174 cydlstgke---------IK..SNGTV..SVPIYINSNIVRGENIF...GNVGD...YLACQNQ..QPYFY....VDHMEL.KaNG.ITPGAAI.SH...LDNGVYINGARI..LSTNTP..K.TNIFSI...ADNNIYPLDIN.M.FfVVPN.TIG.SS..LVISPGETLMTLRLYKYST....SNSSHgyegvQE...NFTW-v..............
A0A2G8E182_9GAMM/28-179 .........CRNKQTGQQ-L..RGGDS..PVVIPLSRQITPGEVIF...IDLWK...YYECRNE..EPYFY....DDFMYL.E.DN.GISTVLN.KD...FEVGAYINGGKYdiPVPYTQ..I.FKLPWH...GDGNWHAIPFR.V.F.YK-V.SET.PGylTRISKGQEIATVRLYKYAHfkggTESDH.....PR...HFIWK...............
A0A198GCC4_9GAMM/29-180 ....ckdat---GFTLNSAS..GTATA..SVYVNLQPNLGTGQNLV...VDLSQ...SISCRND..DPTVR....NDLVNM.I.KG.SAYGGAL.SQ...FRGSLRYYGTSY..TFPLGS..P.THQQNF...TSSSYTPWNTQ.L.Y.LTPV.SAA.GG..VVINKGALFASLVMYQVGSn..iIGGGN....vHT..aTFTWN...............
W1EPQ2_KLEPN/8-112 .........CKTATGATIPI..GGGSA..NVYVNLTPAVNVGQNLV...VDLST...QIFCHND..YPETI....TDYVTL.Q.RG.SAYGGVL.SS...FSGTVKYNGTSY..PFPTTT..E.TARVIY...DSRTDKPC---.-.-.----.---.--..-------------------....-----.....--...-----gasc...........
#=GC SS_cons .........EEETTSCEEBC..TSEEE..EEEE---SBEETTSEEE...EEGGG...TEEEE-S..STTTT...T-EEEEE.E.CC.EEEHHHH.CC...CEEEEEETTEEE..EESBSS..-.---EEE...-SSS-EE--EE.E.E.EEES.TTT.TE..EEE-TTSEEEEEEEEEEES....STT-E.....EE...EEEEE...............
#=GC seq_cons .........Cpsssssph.h..GuGoA..sVaVsLsPslssGQNLV...VDLSs...pItC+ND..hPpsh....sDalsL.p.pG.SAauGlL.ss...FsGolpasGsoY..PFPhoo..p.Tshlph...sspo.pPhPsp.L.Y.LTPl.SsA.uG..VsIpuGslIAsLhhaphss....hsuss..........pFhWN...............
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