GenomeNet

Database: Pfam
Entry: Gp_UL130
LinkDB: Gp_UL130
Original site: Gp_UL130 
#=GF ID   Gp_UL130
#=GF AC   PF11668.10
#=GF DE   HCMV glycoprotein pUL130
#=GF AU   Pollington J;0000-0002-8158-8998
#=GF SE   Pfam-B_002736 (release 23.0)
#=GF GA   25.00 25.00;
#=GF TC   28.30 30.30;
#=GF NC   22.80 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   15956581
#=GF RT   Human cytomegalovirus UL130 protein promotes endothelial cell
#=GF RT   infection through a producer cell modification of the virion. 
#=GF RA   Patrone M, Secchi M, Fiorina L, Ierardi M, Milanesi G, Gallina
#=GF RA   A; 
#=GF RL   J Virol. 2005;79:8361-8373.
#=GF DR   INTERPRO; IPR021038;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins represents pUL130 from Human
#=GF CC   cytomegalovirus, a glycoprotein secreted from infected cells
#=GF CC   that is incorporated into the virion envelope as a Golgi-matured
#=GF CC   form. The protein promotes endothelial cell infection through a
#=GF CC   producer cell modification of the virion [1].
#=GF SQ   9
#=GS A8T7L2_HCMV/56-214      AC A8T7L2.1
#=GS A0A0K1H017_9BETA/2-85   AC A0A0K1H017.1
#=GS UL130_HCMVM/56-214      AC F5HCP3.1
#=GS UL130_HCMVM/56-214      DR PDB; 5VOC D; 56-214;
#=GS UL130_HCMVM/56-214      DR PDB; 5VOB D; 56-214;
#=GS UL130_HCMVM/56-214      DR PDB; 5VOD D; 56-214;
#=GS UL130_HCMVA/56-214      AC P16772.1
#=GS G8XT22_9BETA/21-179     AC G8XT22.1
#=GS G8XUI3_9BETA/18-181     AC G8XUI3.1
#=GS A0A0K1H080_9BETA/39-97  AC A0A0K1H080.1
#=GS G8XTI0_SCMVC/29-184     AC G8XTI0.1
#=GS Q8QRY3_9BETA/84-242     AC Q8QRY3.1
A8T7L2_HCMV/56-214                 ......................YCPFIYPSPPRSPLQFSGFQRVLTGPECRNETLYLLYNREGQTLVERSSTWVKKVIWYLSGRNQTILQRMPRTASKPSDGNVQI.SVED...AKIFGAHMVP..KQTKLLRFVVNDGTRYQMCVMKLESWAHVFRDYSVSFQVRLTFT..EAN.NQ...TY..TFCTHPNLIV...
A0A0K1H017_9BETA/2-85              ................atspat--------------------------------------------------------------------------------SMNI.TEEE...KKTFAAHMIP..MRSTTLRYIVKDGVEVEHCQMRVITWAKTEANF-ISFKVKIELS..NAY.RR...PS..SICTRPNILV...
UL130_HCMVM/56-214                 ......................YCPFLYPSPPRSPLQFSGFQRVSTGPECRNETLYLLYNREGQTLVERSSTWVKKVIWYLSGRNQTILQRMPRTASKPSDGNVQI.SVED...AKIFGAHMVP..KQTKLLRFVVNDGTRYQMCVMKLESWAHVFRDYSVSFQVRLTFT..EAN.NQ...TY..TFCTHPNLIV...
#=GR UL130_HCMVM/56-214      SS    ......................G----S------GGGEEEEEEEE--GGGTT-EEEEEEETTS-EEEEE--HHHHHHHHHHHHHT-HHHHHHHHHHHSSS------.-HHH...HHHHHHHS-S..EEEEEEEEEEEETTEEEEEEEEEEEEEEE-TTS-EEEEEEEEEE..ETT.--...TT..-SSS---B--...
UL130_HCMVA/56-214                 ......................YCPFLYPSPPRSPLQFSGFQQVSTGPECRNETLYLLYNREGQTLVERSSTWVKKVIWYLSGRNQTILQRMPQTASKPSDGNVQI.SVED...AKIFGAHMVP..KQTKLLRFVVNDGTRYQMCVMKLESWAHVFRDYSVSFQVRLTFT..EAN.NQ...TY..TFCTHPNLIV...
G8XT22_9BETA/21-179                cpihplplmhanlfvsytnyta-------------------------INCT-QKLFALHTLNNKTLIVNDSKWTRQVIAYIDGKDL-LMFRLLRNISACNNMTLSL.SQDEktlAKRIFPHPVS..KQIP-LGYRVRDGSRWTNCIFHIQTVVLMKSENNIQFQFKIELR..HAY.STqgvVS..TMCTHPY---fst
G8XUI3_9BETA/18-181                ...............dlncpsq------P-SPRTPVVYFVSHQPYTSLNCT-PSLYALRTVSNKTLIVGDSAWTRQIINYVNGRNMLMF-RLIRELVTQNN-ITQIpQHND...RTVFDRYFSNliQMITVMQYQARDALAWISCILEIQTMAMEKYDDSNTIQFRLALQvrHAHaEQ...GFksTICTHPY---fst
A0A0K1H080_9BETA/39-97             ......................FCP-MYPSPRQNFALFTSYTTHQTGPECGNTSLYIFHNKYNQYLIERPSAWSNRLAFYL-------------------------.----...----------..--------------------------------------------..---.--...--..----------r..
G8XTI0_SCMVC/29-184                .....................l-CP-VQPSPPQDIGLFRAYDIDGPKRECGNATLYILHTHFGQSLIEKPSPWVTKLVNYLSGRNHPVFQKFTKVAATPTQ-IINI.TEEE...KTTFSTHMIS..KNSKLLLYKVKDGPETHICQMRVTTWATTSRGY-ITFQAKIDLS..SAT.RK...FN..NICVRPNLL-a..
Q8QRY3_9BETA/84-242                ......................YCPLTFPSPPRRLSEFTRYHEVPGGPSCNNETLVLLYNRDGQTLIERPSPWVKKVTWYLSGRDHPVFQRFAKTASTANDGNVQI.RTDD...AKVFGSHMVP..KQTKLLRFVINDGTRYEMCIMKLETWAHVFRDYSVAFQTRLTFT..QAN.NQ...TY..SYCTHPNLLV...
#=GC SS_cons                       ......................G----S------GGGEEEEEEEE--GGGTT-EEEEEEETTS-EEEEE--HHHHHHHHHHHHHT-HHHHHHHHHHHSSS------.-HHH...HHHHHHHS-S..EEEEEEEEEEEETTEEEEEEEEEEEEEEE-TTS-EEEEEEEEEE..ETT.--...TT..-SSS---B--...
#=GC seq_cons                      .......................CP.h.PSPPps.h.Fpsapps.su.pCpNpoLYlLas+psQTLlE+sSsWs++llhYLsGRs..lh.Rh.+shupsss.slpI.o.--...tKhFusHMls..KpoplLpahVpDGscaphClM+lpoWApshp-asloFQs+lsho..pAp.pp...s...ohCTHPNll....
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