GenomeNet

Database: Pfam
Entry: HHH_3
LinkDB: HHH_3
Original site: HHH_3 
#=GF ID   HHH_3
#=GF AC   PF12836.8
#=GF DE   Helix-hairpin-helix motif
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Jackhmmer:Q182I3
#=GF GA   27.00 27.00;
#=GF TC   27.00 27.00;
#=GF NC   26.90 26.90;
#=GF BM   hmmbuild --amino HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   8692686
#=GF RT   The helix-hairpin-helix DNA-binding motif: a structural basis
#=GF RT   for non-sequence-specific recognition of DNA. 
#=GF RA   Doherty AJ, Serpell LC, Ponting CP; 
#=GF RL   Nucleic Acids Res 1996;24:2488-2497.
#=GF RN   [2]
#=GF RM   18439896
#=GF RT   Structural biochemistry of a bacterial checkpoint protein
#=GF RT   reveals diadenylate cyclase activity regulated by DNA
#=GF RT   recombination intermediates. 
#=GF RA   Witte G, Hartung S, Buttner K, Hopfner KP; 
#=GF RL   Mol Cell. 2008;30:167-178.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   The HhH domain is a short DNA-binding domain [2].
#=GF SQ   13736
#=GS E0NNI7_9FIRM/128-191        AC E0NNI7.1
#=GS A0A0K1R8Z5_9CORY/140-204    AC A0A0K1R8Z5.1
#=GS A0A445GK99_GLYSO/642-696    AC A0A445GK99.1
#=GS K9QM97_NOSS7/479-541        AC K9QM97.1
#=GS A0A1G6VH31_9PSEU/111-174    AC A0A1G6VH31.1
#=GS M9M3J0_PAEPP/504-568        AC M9M3J0.1
#=GS F7YU91_9THEM/46-108         AC F7YU91.1
#=GS C4GM10_9NEIS/39-101         AC C4GM10.1
#=GS A0A1B1FY34_9BACT/62-125     AC A0A1B1FY34.1
#=GS A0A1H3YGJ5_9DELT/26-88      AC A0A1H3YGJ5.1
#=GS A0A1H5B8S0_9ACTN/169-233    AC A0A1H5B8S0.1
#=GS A0A3A9Z3I5_9ACTN/222-285    AC A0A3A9Z3I5.1
#=GS D2TLR8_CITRI/58-123         AC D2TLR8.1
#=GS U2CNF6_9CLOT/479-543        AC U2CNF6.1
#=GS A0A411X6L3_9BURK/503-567    AC A0A411X6L3.1
#=GS A0A1U7CQ87_9BACT/702-766    AC A0A1U7CQ87.1
#=GS A0A316B9J3_9BACT/95-157     AC A0A316B9J3.1
#=GS A0A2H5AYF9_9ACTN/215-278    AC A0A2H5AYF9.1
#=GS A0A371PFC8_9BACL/513-577    AC A0A371PFC8.1
#=GS A0A0A0A571_CHAVO/128-191    AC A0A0A0A571.1
#=GS A4X5M0_SALTO/493-557        AC A4X5M0.1
#=GS A0A1T1HG91_OCELI/489-553    AC A0A1T1HG91.1
#=GS A0A371PE58_9BACL/250-313    AC A0A371PE58.1
#=GS A0A2P8HMM3_9BACT/65-128     AC A0A2P8HMM3.1
#=GS A0A0W7WIZ3_9RHOB/490-554    AC A0A0W7WIZ3.1
#=GS A0A0R2JYW3_9LACO/510-574    AC A0A0R2JYW3.1
#=GS A0A2S6FZF5_9CLOT/483-547    AC A0A2S6FZF5.1
#=GS A0A268E191_9BACI/485-549    AC A0A268E191.1
#=GS M3C7V8_STRMB/91-155         AC M3C7V8.1
#=GS Q12QB3_SHEDO/422-482        AC Q12QB3.1
#=GS A0A088EX58_9SPHI/57-120     AC A0A088EX58.1
#=GS R9KEQ2_9FIRM/144-208        AC R9KEQ2.1
#=GS A0A1P8JWP2_9BURK/507-571    AC A0A1P8JWP2.1
#=GS A0A498CWS4_9FIRM/60-123     AC A0A498CWS4.1
#=GS A0A0Q8V1L2_9MICO/147-210    AC A0A0Q8V1L2.1
#=GS A0A2U1K4Q1_9BACI/139-203    AC A0A2U1K4Q1.1
#=GS A0A1D2NCU1_ORCCI/211-272    AC A0A1D2NCU1.1
#=GS A0A1W6SST4_9PROT/19-81      AC A0A1W6SST4.1
#=GS S6AG06_SULDS/502-566        AC S6AG06.1
#=GS A0A2U1T3D7_9MICO/108-171    AC A0A2U1T3D7.1
#=GS A0A3D9KH01_9BACL/492-556    AC A0A3D9KH01.1
#=GS F0P038_WEEVC/167-229        AC F0P038.1
#=GS F9DB68_9BACT/200-255        AC F9DB68.1
#=GS A0A1B8WRE5_9BACI/225-288    AC A0A1B8WRE5.1
#=GS Q9RXU9_DEIRA/62-122         AC Q9RXU9.1
#=GS A0A0R2F9Y7_9LACO/150-214    AC A0A0R2F9Y7.1
#=GS A0A1H4LS38_9FLAO/229-293    AC A0A1H4LS38.1
#=GS A0A1H0S0V1_9CLOT/168-232    AC A0A1H0S0V1.1
#=GS A0A1P9X2G4_9BACT/59-122     AC A0A1P9X2G4.1
#=GS A0A2Y9ERN6_PHYMC/602-657    AC A0A2Y9ERN6.1
#=GS C6W497_DYAFD/475-539        AC C6W497.1
#=GS B3QUX6_CHLT3/486-550        AC B3QUX6.1
#=GS A0A2A3AFB3_9MICC/270-334    AC A0A2A3AFB3.1
#=GS A0A179SY29_9BACI/486-550    AC A0A179SY29.1
#=GS A0A1M6HUT2_9FLAO/162-220    AC A0A1M6HUT2.1
#=GS A0A1C6UGZ5_9ACTN/508-572    AC A0A1C6UGZ5.1
#=GS A0A2P8G4E7_9BACL/482-546    AC A0A2P8G4E7.1
#=GS A0A3D9SZS3_9ACTN/501-565    AC A0A3D9SZS3.1
#=GS A0A177I9S8_9CORY/479-543    AC A0A177I9S8.1
#=GS G2IZF9_PSEUL/17-81          AC G2IZF9.1
#=GS A0A1R4HHP7_9GAMM/16-80      AC A0A1R4HHP7.1
#=GS A0A495BVA8_9BACT/42-102     AC A0A495BVA8.1
#=GS Y0KGN4_9PROT/17-81          AC Y0KGN4.1
#=GS A0A174HDN8_9BACE/86-149     AC A0A174HDN8.1
#=GS A0A0K0GEF4_9FIRM/139-202    AC A0A0K0GEF4.1
#=GS W2USR3_9FLAO/478-542        AC W2USR3.1
#=GS R6EFJ8_9BACE/172-234        AC R6EFJ8.1
#=GS A0A1G8SF24_9FIRM/127-191    AC A0A1G8SF24.1
#=GS A0A1H7ZUK7_9PAST/492-556    AC A0A1H7ZUK7.1
#=GS R6E7Q7_9BACT/248-312        AC R6E7Q7.1
#=GS L8XYF8_9GAMM/20-84          AC L8XYF8.1
#=GS A0A0M3T5G1_9MICC/178-241    AC A0A0M3T5G1.1
#=GS A0A1W7D170_9ACTN/291-354    AC A0A1W7D170.1
#=GS A0A091D7X8_FUKDA/35-99      AC A0A091D7X8.1
#=GS R5FHL1_9BACT/53-116         AC R5FHL1.1
#=GS A0A1H4DUX7_9GAMM/482-546    AC A0A1H4DUX7.1
#=GS A0A0P1MG42_9BACT/50-107     AC A0A0P1MG42.1
#=GS C0GIG1_9FIRM/481-545        AC C0GIG1.1
#=GS D8G3J6_9CYAN/100-164        AC D8G3J6.1
#=GS A0A410GBV8_9BURK/512-576    AC A0A410GBV8.1
#=GS R5K1F4_9CLOT/479-543        AC R5K1F4.1
#=GS A0A1M4T6G5_9FIRM/484-548    AC A0A1M4T6G5.1
#=GS A0A4U8UFV0_9HELI/15-76      AC A0A4U8UFV0.1
#=GS L0FTR4_ECHVK/98-159         AC L0FTR4.1
#=GS A0A3P1SUM6_9BACT/166-225    AC A0A3P1SUM6.1
#=GS A0A2T2YJ77_9BACT/481-545    AC A0A2T2YJ77.1
#=GS A0A2W1N062_9FLAO/137-197    AC A0A2W1N062.1
#=GS A0A3P5X8F7_9MICC/184-246    AC A0A3P5X8F7.1
#=GS B2JF13_PARP8/17-80          AC B2JF13.1
#=GS A0A078KWD3_9GAMM/488-552    AC A0A078KWD3.1
#=GS A0A1E4V553_9PSED/39-103     AC A0A1E4V553.1
#=GS A0A0N9UQP4_SPHMC/46-100     AC A0A0N9UQP4.1
#=GS R6QAI8_9FIRM/87-150         AC R6QAI8.1
#=GS I3Y531_THIV6/488-552        AC I3Y531.1
#=GS F2BGU8_9NEIS/20-82          AC F2BGU8.1
#=GS H1HLN5_9BACT/63-125         AC H1HLN5.1
#=GS K9ECY4_9ACTO/281-345        AC K9ECY4.1
#=GS A0A101UGD3_9ACTN/498-562    AC A0A101UGD3.1
#=GS A0A370DFA1_9GAMM/21-86      AC A0A370DFA1.1
#=GS A0A239U167_9STAP/161-225    AC A0A239U167.1
#=GS T2KN76_FORAG/202-264        AC T2KN76.1
#=GS R6Q770_9FIRM/476-540        AC R6Q770.1
#=GS A0A1U7QEG9_MESAU/586-641    AC A0A1U7QEG9.1
#=GS A0A0L6TDX7_9BURK/541-605    AC A0A0L6TDX7.1
#=GS F4PFV7_BATDJ/363-421        AC F4PFV7.1
#=GS A0A0A2UUQ3_9BACI/125-189    AC A0A0A2UUQ3.1
#=GS A0A2P8CJE8_9BACT/242-303    AC A0A2P8CJE8.1
#=GS A0A257L7G4_9BACT/172-236    AC A0A257L7G4.1
#=GS A0A1G9LBY8_9BACT/237-290    AC A0A1G9LBY8.1
#=GS A0A1V4I935_9FIRM/477-541    AC A0A1V4I935.1
#=GS A0A374TBK1_9BACT/79-142     AC A0A374TBK1.1
#=GS A0A0M9ZI62_9ACTN/516-580    AC A0A0M9ZI62.1
#=GS A0A1J0A4X4_9ENTE/139-203    AC A0A1J0A4X4.1
#=GS A0A176TA08_9FLAO/230-293    AC A0A176TA08.1
#=GS U7UHJ3_9FIRM/473-537        AC U7UHJ3.1
#=GS K9UMM2_CHAP6/99-162         AC K9UMM2.1
#=GS A0A3N4MDW0_9BACT/477-541    AC A0A3N4MDW0.1
#=GS R6DSF6_9FIRM/153-217        AC R6DSF6.1
#=GS M5EGN7_9FIRM/511-575        AC M5EGN7.1
#=GS A0A1C5GC75_9ACTN/495-559    AC A0A1C5GC75.1
#=GS A0A0M2VDB4_9GAMM/489-553    AC A0A0M2VDB4.1
#=GS S2E7F5_9BACT/99-162         AC S2E7F5.1
#=GS F8A1S5_CELGA/214-276        AC F8A1S5.1
#=GS A0A1Z4JM33_LEPBY/46-108     AC A0A1Z4JM33.1
#=GS A0A177NXI3_9RHIZ/50-109     AC A0A177NXI3.1
#=GS G2SRN3_LACRR/488-552        AC G2SRN3.1
#=GS A0A3Q1JLC2_ANATE/718-782    AC A0A3Q1JLC2.1
#=GS A0A1S3Q087_SALSA/124-187    AC A0A1S3Q087.1
#=GS A0A1I5S025_9BACT/84-144     AC A0A1I5S025.1
#=GS A0A239DH92_9ACTN/137-198    AC A0A239DH92.1
#=GS A0A1E5LHW4_9BACI/129-193    AC A0A1E5LHW4.1
#=GS R6YYF6_9BACE/80-143         AC R6YYF6.1
#=GS A0A2U3W5K3_ODORO/713-777    AC A0A2U3W5K3.1
#=GS A0A202DFB4_9ARCH/460-518    AC A0A202DFB4.1
#=GS A0A2U8W7G0_9RHIZ/188-246    AC A0A2U8W7G0.1
#=GS A0A1I3BMG5_9LACT/355-413    AC A0A1I3BMG5.1
#=GS A0A1T5KEC3_9BACT/483-547    AC A0A1T5KEC3.1
#=GS A0A268JDM9_9BACI/340-396    AC A0A268JDM9.1
#=GS A0A430KNS8_9GAMM/24-87      AC A0A430KNS8.1
#=GS A0A2T6F5E5_9BURK/20-80      AC A0A2T6F5E5.1
#=GS A0A327X0X2_9BACT/480-544    AC A0A327X0X2.1
#=GS F0T7A7_METLA/305-360        AC F0T7A7.1
#=GS Q63S13_BURPS/18-80          AC Q63S13.1
#=GS T0CY92_ALIAG/209-273        AC T0CY92.1
#=GS A0A0F4KRB9_9LACO/144-208    AC A0A0F4KRB9.1
#=GS A0A096MGI4_POEFO/562-616    AC A0A096MGI4.1
#=GS A0A3S3P8Q1_9MICO/127-191    AC A0A3S3P8Q1.1
#=GS A0A172TJ53_9BACL/512-576    AC A0A172TJ53.1
#=GS A0A1C2HEC4_9RHOB/488-552    AC A0A1C2HEC4.1
#=GS A0A365SK42_9PSED/90-161     AC A0A365SK42.1
#=GS A0A2A2EK15_9BIFI/165-228    AC A0A2A2EK15.1
#=GS G7MBF3_9CLOT/482-546        AC G7MBF3.1
#=GS R5NZM8_9BACT/180-234        AC R5NZM8.1
#=GS A0A1S9MEH7_9MICC/508-572    AC A0A1S9MEH7.1
#=GS A0A2C1K8W4_9BACI/486-550    AC A0A2C1K8W4.1
#=GS A0A0Q6RBK3_9MICO/91-155     AC A0A0Q6RBK3.1
#=GS K9SP46_9SYNE/56-118         AC K9SP46.1
#=GS G5JT55_STRCG/151-215        AC G5JT55.1
#=GS A0A2A5RKX8_9LACT/476-540    AC A0A2A5RKX8.1
#=GS A0A024QF87_9BACI/487-551    AC A0A024QF87.1
#=GS A0A0Q5W2X3_9RHIZ/496-560    AC A0A0Q5W2X3.1
#=GS A0A0E0HFJ7_ORYNI/521-575    AC A0A0E0HFJ7.1
#=GS A0A224X5X9_9LACT/477-541    AC A0A224X5X9.1
#=GS A0A257IQJ2_9BACT/178-240    AC A0A257IQJ2.1
#=GS A0A1K1RM68_9FLAO/220-283    AC A0A1K1RM68.1
#=GS A0A399D3P1_9BACT/304-367    AC A0A399D3P1.1
#=GS A0A1D2IHZ6_9ACTN/255-318    AC A0A1D2IHZ6.1
#=GS A0A2R5FT82_NOSCO/112-176    AC A0A2R5FT82.1
#=GS A0A4D6HFT8_9EURY/522-565    AC A0A4D6HFT8.1
#=GS R7FJH6_9CLOT/490-554        AC R7FJH6.1
#=GS I2F2U0_9BACT/119-181        AC I2F2U0.1
#=GS A0A1F1EE23_9PORP/44-106     AC A0A1F1EE23.1
#=GS I4D204_DESAJ/481-545        AC I4D204.1
#=GS A0A1C0A9H6_9FIRM/175-235    AC A0A1C0A9H6.1
#=GS A0A1W2BSU4_9SPHI/477-541    AC A0A1W2BSU4.1
#=GS C4XJK5_DESMR/43-103         AC C4XJK5.1
#=GS A0A2U1JHD1_9FLAO/157-221    AC A0A2U1JHD1.1
#=GS A0A2N7UQK0_9GAMM/28-92      AC A0A2N7UQK0.1
#=GS G2E5I6_9GAMM/488-552        AC G2E5I6.1
#=GS A0A3M2ME15_9ACTN/275-339    AC A0A3M2ME15.1
#=GS A0A220S0U0_9NEIS/480-544    AC A0A220S0U0.1
#=GS A0A238Z1I7_9RHOB/489-553    AC A0A238Z1I7.1
#=GS A0A256BHG9_9CYAN/488-552    AC A0A256BHG9.1
#=GS A0A1G6RKB6_9BACT/481-545    AC A0A1G6RKB6.1
#=GS A0A0B2A632_9MICO/144-208    AC A0A0B2A632.1
#=GS A9NGM9_ACHLI/101-164        AC A9NGM9.1
#=GS F7C632_HORSE/604-659        AC F7C632.2
#=GS A0A371PMQ5_9BACL/121-185    AC A0A371PMQ5.1
#=GS R6SDV5_9BACE/84-145         AC R6SDV5.1
#=GS D4W1D5_9FIRM/127-191        AC D4W1D5.1
#=GS A0A1D6MC28_MAIZE/624-687    AC A0A1D6MC28.1
#=GS A0A2A2S4H2_9SPHI/208-272    AC A0A2A2S4H2.1
#=GS W5WI43_9PSEU/490-554        AC W5WI43.1
#=GS A0A060LSZ3_9BACI/173-230    AC A0A060LSZ3.1
#=GS R6AQK4_9BACT/228-291        AC R6AQK4.1
#=GS A0A2D0NFM9_9BACT/155-217    AC A0A2D0NFM9.1
#=GS Q1YPV7_9GAMM/39-104         AC Q1YPV7.1
#=GS W7ZFS1_9BACI/141-205        AC W7ZFS1.1
#=GS C4FEZ1_9BIFI/152-216        AC C4FEZ1.1
#=GS A8FFE5_BACP2/143-207        AC A8FFE5.1
#=GS A0A1H1ZKW2_9BACL/248-311    AC A0A1H1ZKW2.1
#=GS A0A1H3W8F2_9GAMM/56-121     AC A0A1H3W8F2.1
#=GS A0A3R9PB49_9BACI/137-201    AC A0A3R9PB49.1
#=GS A0A0U5B1L7_9BACL/482-546    AC A0A0U5B1L7.1
#=GS A0A2P6C333_9BACT/76-139     AC A0A2P6C333.1
#=GS A0A1N6FQ29_9PROT/503-567    AC A0A1N6FQ29.1
#=GS A0A0D8CSM4_9GAMM/488-552    AC A0A0D8CSM4.1
#=GS A0A1E3XEA4_9BACT/32-94      AC A0A1E3XEA4.1
#=GS A0A1W2D3Y1_9RHIZ/492-556    AC A0A1W2D3Y1.1
#=GS A0A124DZ29_9MYCO/206-269    AC A0A124DZ29.1
#=GS A0A444YXI1_ARAHY/563-617    AC A0A444YXI1.1
#=GS D6GT18_FILAD/154-218        AC D6GT18.1
#=GS A0A1T0B3D3_9PAST/491-555    AC A0A1T0B3D3.1
#=GS A0A117QKQ3_9ACTN/310-373    AC A0A117QKQ3.1
#=GS A0A2S9IIE2_9GAMM/56-120     AC A0A2S9IIE2.1
#=GS A0A0P7C4Y7_9BACT/179-243    AC A0A0P7C4Y7.1
#=GS K6TU84_9CLOT/482-546        AC K6TU84.1
#=GS A0A416RCQ8_9FIRM/70-133     AC A0A416RCQ8.1
#=GS A6VTC2_MARMS/489-553        AC A6VTC2.1
#=GS E1R7P2_SEDSS/500-564        AC E1R7P2.1
#=GS B1C0Z1_9FIRM/1-48           AC B1C0Z1.1
#=GS A0A0R2LTD4_9LACO/163-226    AC A0A0R2LTD4.1
#=GS A0A1M7P702_9BACT/480-544    AC A0A1M7P702.1
#=GS I4BLI3_MYCCN/227-291        AC I4BLI3.1
#=GS R6Y8E4_9BACT/211-273        AC R6Y8E4.1
#=GS A0A1E8GLS6_9LACT/162-226    AC A0A1E8GLS6.1
#=GS Q8YSV5_NOSS1/38-101         AC Q8YSV5.1
#=GS K0JSC6_SACES/172-236        AC K0JSC6.1
#=GS A0A1G7DL22_9FLAO/478-542    AC A0A1G7DL22.1
#=GS A0A0N0CYH8_9BACT/79-141     AC A0A0N0CYH8.1
#=GS A0A178UBX1_ARATH/645-698    AC A0A178UBX1.1
#=GS A0A255Z9Y3_9FLAO/243-305    AC A0A255Z9Y3.1
#=GS A0A0S4KWM1_9BACT/46-105     AC A0A0S4KWM1.1
#=GS G2KV00_LACSM/492-556        AC G2KV00.1
#=GS A0A1H8EFV4_9RHOB/489-553    AC A0A1H8EFV4.1
#=GS B1Y2N3_LEPCP/18-76          AC B1Y2N3.1
#=GS A0A2A2ALE6_9BURK/511-575    AC A0A2A2ALE6.1
#=GS A0A2I2YSQ9_GORGO/595-650    AC A0A2I2YSQ9.1
#=GS A0A1L7CXL5_9CORY/478-542    AC A0A1L7CXL5.1
#=GS I3MBP6_ICTTR/134-196        AC I3MBP6.2
#=GS A0A318F1W4_9ACTN/261-324    AC A0A318F1W4.1
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#=GS A0A1I3SZM6_9ALTE/491-555    AC A0A1I3SZM6.1
#=GS B7GFP8_ANOFW/492-556        AC B7GFP8.1
#=GS R6BZN4_9CLOT/186-250        AC R6BZN4.1
#=GS V5XMK4_ENTMU/123-187        AC V5XMK4.1
#=GS R5NRV2_9FIRM/481-545        AC R5NRV2.1
#=GS F6CXG0_MARPP/29-93          AC F6CXG0.1
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#=GS G8AQ49_AZOBR/490-554        AC G8AQ49.1
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