GenomeNet

Database: Pfam
Entry: HMMR_C
LinkDB: HMMR_C
Original site: HMMR_C 
#=GF ID   HMMR_C
#=GF AC   PF15908.7
#=GF DE   Hyaluronan mediated motility receptor C-terminal
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:O75330
#=GF GA   28.60 28.60;
#=GF TC   28.70 28.60;
#=GF NC   28.50 28.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Coiled-coil
#=GF RN   [1]
#=GF RM   8890751
#=GF RT   The characterization of a human RHAMM cDNA: conservation of the
#=GF RT   hyaluronan-binding domains.
#=GF RA   Wang C, Entwistle J, Hou G, Li Q, Turley EA;
#=GF RL   Gene. 1996;174:299-306.
#=GF RN   [2]
#=GF RM   9601098
#=GF RT   The human hyaluronan receptor RHAMM is expressed as an
#=GF RT   intracellular protein in breast cancer cells.
#=GF RA   Assmann V, Marshall JF, Fieber C, Hofmann M, Hart IR;
#=GF RL   J Cell Sci. 1998;111:1685-1694.
#=GF RN   [3]
#=GF RM   19064580
#=GF RT   Hyaluronan-mediated motility receptor gene single nucleotide
#=GF RT   polymorphisms and risk of breast cancer.
#=GF RA   Kalmyrzaev B, Pharoah PD, Easton DF, Ponder BA, Dunning AM;
#=GF RL   Cancer Epidemiol Biomarkers Prev. 2008;17:3618-3620.
#=GF DR   INTERPRO; IPR031794;
#=GF DR   SO; 0001080; coiled_coil;
#=GF CC   HMMR_C is the C-terminal region of eukaryotic
#=GF CC   hyaluronan-mediated motility receptor proteins. The protein is
#=GF CC   functionally associated with BRCA1 and thus predicted to be a
#=GF CC   common, low-penetrance breast cancer candidate.
#=GF SQ   673
#=GS A0A553RFN5_9TELE/756-914    AC A0A553RFN5.1
#=GS G3TJ55_LOXAF/553-709        AC G3TJ55.1
#=GS A0A2K5Z7H4_MANLE/1265-1388  AC A0A2K5Z7H4.1
#=GS A0A091FMW1_9AVES/1256-1380  AC A0A091FMW1.1
#=GS A0A5N5PR30_PANHP/1252-1360  AC A0A5N5PR30.1
#=GS A0A553RFL5_9TELE/731-887    AC A0A553RFL5.1
#=GS A0A1D5P401_CHICK/1272-1396  AC A0A1D5P401.1
#=GS A0A672IH02_SALFA/1239-1313  AC A0A672IH02.1
#=GS A0A2K6TBT7_SAIBB/494-641    AC A0A2K6TBT7.1
#=GS A0A5N4CZV6_CAMDR/1169-1292  AC A0A5N4CZV6.1
#=GS L5LPJ9_MYODS/544-700        AC L5LPJ9.1
#=GS A0A484H231_SOUCH/544-700    AC A0A484H231.1
#=GS M4AGF6_XIPMA/1259-1379      AC M4AGF6.2
#=GS A0A195D361_9HYME/835-970    AC A0A195D361.1
#=GS A0A485NSJ1_LYNPA/542-698    AC A0A485NSJ1.1
#=GS A0A2Y9QSQ5_TRIMA/587-743    AC A0A2Y9QSQ5.1
#=GS A0A452QCA4_URSAM/1233-1357  AC A0A452QCA4.1
#=GS A0A3Q1G1I5_9TELE/1150-1268  AC A0A3Q1G1I5.1
#=GS A0A384D4W8_URSMA/1265-1388  AC A0A384D4W8.1
#=GS A0A3Q7RU08_VULVU/1359-1480  AC A0A3Q7RU08.1
#=GS A0A673UY92_SURSU/553-709    AC A0A673UY92.1
#=GS A0A2K6C5L0_MACNE/553-709    AC A0A2K6C5L0.1
#=GS H2MME0_ORYLA/1246-1387      AC H2MME0.2
#=GS A0A2I3HW09_NOMLE/466-622    AC A0A2I3HW09.1
#=GS A0A096M2C0_POEFO/1258-1380  AC A0A096M2C0.1
#=GS A0A5F9CMQ5_RABIT/502-658    AC A0A5F9CMQ5.1
#=GS A0A3Q7T6A9_VULVU/553-709    AC A0A3Q7T6A9.1
#=GS R4G9R9_ANOCA/559-715        AC R4G9R9.1
#=GS G3WJ93_SARHA/1257-1389      AC G3WJ93.1
#=GS A0A6Q2YAU5_ESOLU/942-1033   AC A0A6Q2YAU5.1
#=GS A0A3Q2HXE7_HORSE/1265-1388  AC A0A3Q2HXE7.1
#=GS A0A5F9D0H6_RABIT/551-657    AC A0A5F9D0H6.1
#=GS W5KEV9_ASTMX/741-895        AC W5KEV9.2
#=GS A0A4W3HT62_CALMI/684-836    AC A0A4W3HT62.1
#=GS A0A2K5LAD8_CERAT/553-709    AC A0A2K5LAD8.1
#=GS A0A3P9BKS8_9CICH/803-963    AC A0A3P9BKS8.1
#=GS A0A498NSY7_LABRO/919-1078   AC A0A498NSY7.1
#=GS A0A2I4BNF9_9TELE/1261-1384  AC A0A2I4BNF9.1
#=GS A0A668AF85_9TELE/909-1026   AC A0A668AF85.1
#=GS A0A218UFC7_9PASE/1207-1330  AC A0A218UFC7.1
#=GS A0A674E3M4_SALTR/1019-1079  AC A0A674E3M4.1
#=GS A0A0R4IPI0_DANRE/742-899    AC A0A0R4IPI0.2
#=GS A0A1Q9DID4_SYMMI/405-492    AC A0A1Q9DID4.1
#=GS A0A091SDF9_NESNO/480-610    AC A0A091SDF9.1
#=GS A0A2K6TR29_SAIBB/537-693    AC A0A2K6TR29.1
#=GS L5KHZ8_PTEAL/1265-1387      AC L5KHZ8.1
#=GS G1NW55_MYOLU/555-711        AC G1NW55.1
#=GS A0A423SVN8_PENVA/1103-1249  AC A0A423SVN8.1
#=GS A0A2R5GAS5_9STRA/1163-1272  AC A0A2R5GAS5.1
#=GS A0A2I2ZI69_GORGO/466-622    AC A0A2I2ZI69.1
#=GS A0A671Z0P9_SPAAU/869-1027   AC A0A671Z0P9.1
#=GS L8GHK3_ACACA/442-566        AC L8GHK3.1
#=GS A0A665UAU2_ECHNA/678-808    AC A0A665UAU2.1
#=GS A0A158P2D3_ATTCE/847-979    AC A0A158P2D3.1
#=GS A0A401PN40_SCYTO/1267-1416  AC A0A401PN40.1
#=GS V8NYV5_OPHHA/457-613        AC V8NYV5.1
#=GS A0A060YJ07_ONCMY/839-987    AC A0A060YJ07.1
#=GS H3AQS5_LATCH/557-711        AC H3AQS5.1
#=GS A0A4W3IA94_CALMI/1275-1414  AC A0A4W3IA94.1
#=GS A0A3S1CCX6_ELYCH/44-188     AC A0A3S1CCX6.1
#=GS W5P3X2_SHEEP/1274-1394      AC W5P3X2.1
#=GS A0A485NPR0_LYNPA/553-709    AC A0A485NPR0.1
#=GS A0A0Q3PT57_AMAAE/507-620    AC A0A0Q3PT57.1
#=GS A0A3P8ZW28_ESOLU/1215-1330  AC A0A3P8ZW28.2
#=GS H2S0G1_TAKRU/856-1017       AC H2S0G1.3
#=GS A0A091NUN5_APAVI/1263-1386  AC A0A091NUN5.1
#=GS A0A3M0J994_HIRRU/508-664    AC A0A3M0J994.1
#=GS A0A3Q2ZVJ2_KRYMA/1236-1333  AC A0A3Q2ZVJ2.1
#=GS A0A2K5EXA4_AOTNA/553-709    AC A0A2K5EXA4.1
#=GS A0A668AT42_9TELE/973-1067   AC A0A668AT42.1
#=GS A0A2Y9GN23_NEOSC/1265-1388  AC A0A2Y9GN23.1
#=GS A0A3P8XKU9_ESOLU/656-803    AC A0A3P8XKU9.1
#=GS A0A0D9RV75_CHLSB/1269-1392  AC A0A0D9RV75.1
#=GS F7BKM4_MONDO/565-719        AC F7BKM4.3
#=GS A0A2Y9FH11_PHYMC/553-709    AC A0A2Y9FH11.1
#=GS A0A2Y9LW78_DELLE/1208-1327  AC A0A2Y9LW78.1
#=GS G1LF72_AILME/676-832        AC G1LF72.1
#=GS A0A4W5JQW6_9TELE/853-1004   AC A0A4W5JQW6.1
#=GS A0A2K5EXB0_AOTNA/466-622    AC A0A2K5EXB0.1
#=GS A0A099Z9S7_TINGU/1266-1392  AC A0A099Z9S7.1
#=GS A0A2K6C5L6_MACNE/549-705    AC A0A2K6C5L6.1
#=GS A0A1S3SPG5_SALSA/1297-1411  AC A0A1S3SPG5.1
#=GS A0A5N3XVV9_MUNRE/1269-1392  AC A0A5N3XVV9.1
#=GS A0A1V9XAP5_9ACAR/883-1014   AC A0A1V9XAP5.1
#=GS H2PAZ8_PONAB/1265-1388      AC H2PAZ8.1
#=GS A0A1L8GWY2_XENLA/1013-1170  AC A0A1L8GWY2.1
#=GS A0A2Y9QG06_TRIMA/566-722    AC A0A2Y9QG06.1
#=GS A0A5C6MK63_9TELE/856-1017   AC A0A5C6MK63.1
#=GS A0A553Q7H3_9TELE/1213-1330  AC A0A553Q7H3.1
#=GS A0A493SWU0_ANAPP/528-685    AC A0A493SWU0.1
#=GS A0A4X2LWI0_VOMUR/1262-1385  AC A0A4X2LWI0.1
#=GS A0A088AT26_APIME/838-971    AC A0A088AT26.1
#=GS F1N331_BOVIN/538-646        AC F1N331.3
#=GS A0A5J5N4T4_MUNRE/538-694    AC A0A5J5N4T4.1
#=GS A0A6Q2WWH7_ESOLU/843-909    AC A0A6Q2WWH7.1
#=GS A0A1E3I0M7_9TREE/482-622    AC A0A1E3I0M7.1
#=GS W5MUN3_LEPOC/675-829        AC W5MUN3.1
#=GS A0A2Y9QKB2_TRIMA/524-704    AC A0A2Y9QKB2.1
#=GS A0A026W9A7_OOCBI/852-986    AC A0A026W9A7.1
#=GS A0A5F4CDR8_CANLF/537-693    AC A0A5F4CDR8.1
#=GS D2A2B7_TRICA/651-802        AC D2A2B7.1
#=GS S7PPV5_MYOBR/612-668        AC S7PPV5.1
#=GS A0A665WJJ3_ECHNA/852-975    AC A0A665WJJ3.1
#=GS A0A2I3SGI4_PANTR/900-1023   AC A0A2I3SGI4.1
#=GS A0A672IGW1_SALFA/1220-1294  AC A0A672IGW1.1
#=GS F1PSL9_CANLF/1263-1384      AC F1PSL9.2
#=GS G3TFD5_LOXAF/1258-1380      AC G3TFD5.1
#=GS A0A0L0D544_THETB/980-1102   AC A0A0L0D544.1
#=GS A0A674MGS1_TAKRU/962-1078   AC A0A674MGS1.1
#=GS U3IZ66_ANAPP/528-685        AC U3IZ66.2
#=GS A0A1S3GCC4_DIPOR/1187-1312  AC A0A1S3GCC4.1
#=GS F6R6N5_HORSE/551-707        AC F6R6N5.3
#=GS A0A5N4AQM1_PHOPY/440-589    AC A0A5N4AQM1.1
#=GS A0A4W6CEJ4_LATCA/879-1040   AC A0A4W6CEJ4.1
#=GS A0A4W6FKR3_LATCA/1210-1329  AC A0A4W6FKR3.1
#=GS Q5KDD5_CRYNJ/476-610        AC Q5KDD5.1
#=GS A0A672TIE2_STRHB/1265-1391  AC A0A672TIE2.1
#=GS A0A5C6NZ28_9TELE/1216-1375  AC A0A5C6NZ28.1
#=GS A0A087QH38_APTFO/1279-1405  AC A0A087QH38.1
#=GS A0A0G2K0M1_RAT/1264-1385    AC A0A0G2K0M1.1
#=GS H2LUU1_ORYLA/873-1030       AC H2LUU1.2
#=GS A0A151WU64_9HYME/838-971    AC A0A151WU64.1
#=GS A0A553NCX0_TIGCA/902-1036   AC A0A553NCX0.1
#=GS A0A2Y9QSE4_TRIMA/577-733    AC A0A2Y9QSE4.1
#=GS A0A2Y9S2C9_PHYMC/596-651    AC A0A2Y9S2C9.1
#=GS A0A669B6Q3_ORENI/934-1045   AC A0A669B6Q3.1
#=GS A0A087VHM8_BALRE/1264-1388  AC A0A087VHM8.1
#=GS A0A3Q4BG97_MOLML/1187-1282  AC A0A3Q4BG97.1
#=GS A0A0L0DF08_THETB/1322-1451  AC A0A0L0DF08.1
#=GS A0A6G0IF61_LARCR/1254-1370  AC A0A6G0IF61.1
#=GS A0A4S2JAZ7_9HYME/815-947    AC A0A4S2JAZ7.1
#=GS A0A1V9ZTX0_9STRA/140-265    AC A0A1V9ZTX0.1
#=GS A0A195BV04_9HYME/724-860    AC A0A195BV04.1
#=GS A0A0T6AYQ7_9SCAR/555-691    AC A0A0T6AYQ7.1
#=GS A0A091MAF2_CARIC/479-609    AC A0A091MAF2.1
#=GS A0A091SIR2_9GRUI/480-610    AC A0A091SIR2.1
#=GS A0A315VKM8_GAMAF/871-1031   AC A0A315VKM8.1
#=GS A0A091EBT2_CORBR/480-610    AC A0A091EBT2.1
#=GS A0A4W2IF29_BOBOX/554-710    AC A0A4W2IF29.1
#=GS A8N6T6_COPC7/506-664        AC A8N6T6.2
#=GS A0A3Q2UWB0_HAPBU/863-1024   AC A0A3Q2UWB0.1
#=GS A0A3Q4GNA5_NEOBR/1215-1317  AC A0A3Q4GNA5.1
#=GS A0A668AXC4_9TELE/980-1083   AC A0A668AXC4.1
#=GS A0A093EL47_TYTAL/480-610    AC A0A093EL47.1
#=GS S7PPV5_MYOBR/571-615        AC S7PPV5.1
#=GS A0A672IGX6_SALFA/1225-1299  AC A0A672IGX6.1
#=GS A0A087X8S8_POEFO/1268-1390  AC A0A087X8S8.2
#=GS L8GI87_ACACA/1079-1206      AC L8GI87.1
#=GS A0A665WJP9_ECHNA/900-1020   AC A0A665WJP9.1
#=GS A0A5G2QG19_PIG/535-692      AC A0A5G2QG19.1
#=GS A0A1S3RPV7_SALSA/950-1101   AC A0A1S3RPV7.1
#=GS A0A3B1K1Q5_ASTMX/1211-1321  AC A0A3B1K1Q5.1
#=GS G1MUG5_MELGA/977-1133       AC G1MUG5.2
#=GS A0A401SGU4_CHIPU/1273-1403  AC A0A401SGU4.1
#=GS A0A3Q7XU93_URSAR/552-708    AC A0A3Q7XU93.1
#=GS M3YV74_MUSPF/1264-1387      AC M3YV74.1
#=GS A0A4Z2GES8_9TELE/719-873    AC A0A4Z2GES8.1
#=GS A0A4W3IAF5_CALMI/863-974    AC A0A4W3IAF5.1
#=GS E1BC41_BOVIN/1267-1387      AC E1BC41.2
#=GS A0A099YTC9_TINGU/479-609    AC A0A099YTC9.1
#=GS A0A1S3HER9_LINUN/572-683    AC A0A1S3HER9.1
#=GS G3Q3J7_GASAC/742-900        AC G3Q3J7.1
#=GS A0A067QYP3_ZOONE/537-693    AC A0A067QYP3.1
#=GS G3H9Y8_CRIGR/488-539        AC G3H9Y8.1
#=GS A0A096N073_PAPAN/235-391    AC A0A096N073.2
#=GS A0A0D2WI30_CAPO3/1195-1321  AC A0A0D2WI30.1
#=GS A0A093FYB7_GAVST/1263-1389  AC A0A093FYB7.1
#=GS K7GSC4_PIG/551-707          AC K7GSC4.2
#=GS A0A2I0MAC3_COLLI/567-723    AC A0A2I0MAC3.1
#=GS A0A3L8SIV7_CHLGU/512-668    AC A0A3L8SIV7.1
#=GS A0A3Q3W743_MOLML/750-897    AC A0A3Q3W743.1
#=GS A0A340WBA3_LIPVE/1265-1383  AC A0A340WBA3.1
#=GS A0A226E1R3_FOLCA/1199-1328  AC A0A226E1R3.1
#=GS A0A6Q2XFH3_ESOLU/656-812    AC A0A6Q2XFH3.1
#=GS A0A383Z9D8_BALAS/554-710    AC A0A383Z9D8.1
#=GS A0A5G2RBP4_PIG/552-708      AC A0A5G2RBP4.1
#=GS A0A671G3N0_RHIFE/466-622    AC A0A671G3N0.1
#=GS T1IPJ7_STRMM/864-1007       AC T1IPJ7.1
#=GS A0A5F8HEW4_MONDO/565-719    AC A0A5F8HEW4.1
#=GS I3LED2_PIG/552-595          AC I3LED2.2
#=GS A0A3Q3RK59_9TELE/1267-1375  AC A0A3Q3RK59.1
#=GS A0A2U9CJ35_SCOMX/1257-1363  AC A0A2U9CJ35.1
#=GS A0A3Q1B8D9_AMPOC/839-1000   AC A0A3Q1B8D9.1
#=GS T0RYJ2_SAPDV/1308-1449      AC T0RYJ2.1
#=GS A0A663DW72_AQUCH/1128-1251  AC A0A663DW72.1
#=GS A0A2I3TJZ9_PANTR/466-622    AC A0A2I3TJZ9.1
#=GS A0A4W3I5B7_CALMI/905-1015   AC A0A4W3I5B7.1
#=GS A0A2K5XA99_MANLE/549-705    AC A0A2K5XA99.1
#=GS A0A3Q3MCV9_9LABR/856-1017   AC A0A3Q3MCV9.1
#=GS A0A3B1JYZ8_ASTMX/1155-1267  AC A0A3B1JYZ8.1
#=GS A0A6A4VC70_AMPAM/378-550    AC A0A6A4VC70.1
#=GS A0A452EG82_CAPHI/1222-1343  AC A0A452EG82.1
#=GS F6X1N8_ORNAN/1039-1195      AC F6X1N8.2
#=GS A0A3P8SS24_AMPPE/717-878    AC A0A3P8SS24.1
#=GS A0A091JSL4_EGRGA/480-610    AC A0A091JSL4.1
#=GS A0A2U9C8D0_SCOMX/875-1036   AC A0A2U9C8D0.1
#=GS A0A2K6PLP3_RHIRO/1264-1387  AC A0A2K6PLP3.1
#=GS H0YTB1_TAEGU/570-726        AC H0YTB1.2
#=GS A0A340X6Z2_LIPVE/553-709    AC A0A340X6Z2.1
#=GS A0A672IIU3_SALFA/1208-1268  AC A0A672IIU3.1
#=GS A0A2K5DLA3_AOTNA/223-347    AC A0A2K5DLA3.1
#=GS A0A671F8G1_RHIFE/1265-1387  AC A0A671F8G1.1
#=GS T0QKP8_SAPDV/121-252        AC T0QKP8.1
#=GS A0A673W3X5_SALTR/973-1124   AC A0A673W3X5.1
#=GS E2RJF8_CANLF/898-1018       AC E2RJF8.3
#=GS F4NZC2_BATDJ/19-162         AC F4NZC2.1
#=GS A0A643BY88_BALPH/1172-1291  AC A0A643BY88.1
#=GS A0A452IFF6_9SAUR/455-611    AC A0A452IFF6.1
#=GS A0A672JR91_SALFA/514-665    AC A0A672JR91.1
#=GS F7E7G6_XENTR/1243-1364      AC F7E7G6.3
#=GS A0A2K5KR47_CERAT/900-1023   AC A0A2K5KR47.1
#=GS A0A6A4JTK8_APOLU/792-952    AC A0A6A4JTK8.1
#=GS A0A1U8CY73_ALLSI/1273-1395  AC A0A1U8CY73.1
#=GS H2PAZ9_PONAB/1264-1387      AC H2PAZ9.1
#=GS G1QXW0_NOMLE/553-709        AC G1QXW0.1
#=GS R7T6E6_CAPTE/912-1072       AC R7T6E6.1
#=GS A0A2Y9HHL6_NEOSC/553-709    AC A0A2Y9HHL6.1
#=GS U3IZL2_ANAPP/1272-1394      AC U3IZL2.2
#=GS A0A2I2US29_FELCA/897-1020   AC A0A2I2US29.2
#=GS A0A2Y9QF65_TRIMA/1186-1309  AC A0A2Y9QF65.1
#=GS A0A287BJ51_PIG/1272-1395    AC A0A287BJ51.1
#=GS A0A2T7PNL1_POMCA/736-887    AC A0A2T7PNL1.1
#=GS A0A671Z0T9_SPAAU/672-828    AC A0A671Z0T9.1
#=GS H3DIZ8_TETNG/1253-1367      AC H3DIZ8.1
#=GS A0A2K5KR52_CERAT/877-1000   AC A0A2K5KR52.1
#=GS A0A4W5NBP2_9TELE/701-849    AC A0A4W5NBP2.1
#=GS A0A444T9T4_ARMVU/3-157      AC A0A444T9T4.1
#=GS S7QAA9_MYOBR/1197-1306      AC S7QAA9.1
#=GS H0WWR3_OTOGA/627-783        AC H0WWR3.1
#=GS A0A087X8N1_POEFO/872-1033   AC A0A087X8N1.2
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G3TJ55_LOXAF/553-709                   ........................................................fk-KQL-.EE.E.A...RK........A..G..K..E.....N...A....V......VEL......T......E......E..S.NKW...RLLY..EELYNKTK.....P.FQ.LQLD....AF.EAE..KQV......LLN.EHGA.A.........QEQ.LNK....LSDSYAKLLGHQNLKQKIKHV...VK....LK.......DENSQLKLEV..SKLRSQ..LAKKK..QSETK.LQEE.L.NKAMG..I.K.HFDPSKA..FHH..ESKEN..F..A..L..K.T..PLKEG.......................................
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